KEGG Orthology (KO) - Homo sapiens (human)

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     KO
 09100 Metabolism
 
 09120 Genetic Information Processing
 
 09130 Environmental Information Processing
 
 09140 Cellular Processes
 
 09150 Organismal Systems
 
 09160 Human Diseases
 
   09161 Cancer: overview
 
   09162 Cancer: specific types
 
   09163 Immune disease
 
   09164 Neurodegenerative disease
 
   09165 Substance dependence
 
   09166 Cardiovascular disease
 
   09167 Endocrine and metabolic disease
 
   09171 Infectious disease: bacterial
     05110 Vibrio cholerae infection [PATH:hsa05110]
     05120 Epithelial cell signaling in Helicobacter pylori infection [PATH:hsa05120]
     05130 Pathogenic Escherichia coli infection [PATH:hsa05130]
     05132 Salmonella infection [PATH:hsa05132]
     05131 Shigellosis [PATH:hsa05131]
     05135 Yersinia infection [PATH:hsa05135]
       2335 FN1; fibronectin 1
       3676 ITGA4; integrin subunit alpha 4
       3678 ITGA5; integrin subunit alpha 5
       3688 ITGB1; integrin subunit beta 1
       391 RHOG; ras homolog family member G
       6714 SRC; SRC proto-oncogene, non-receptor tyrosine kinase
       5747 PTK2; protein tyrosine kinase 2
       2185 PTK2B; protein tyrosine kinase 2 beta
       1398 CRK; CRK proto-oncogene, adaptor protein
       1399 CRKL; CRK like proto-oncogene, adaptor protein
       9564 BCAR1; BCAR1 scaffold protein, Cas family member
       9844 ELMO1; engulfment and cell motility 1
       63916 ELMO2; engulfment and cell motility 2
       1793 DOCK1; dedicator of cytokinesis 1
       102723407 IGH; immunoglobulin heavy variable 4-38-2-like
       2212 FCGR2A; Fc fragment of IgG receptor IIa
       5879 RAC1; Rac family small GTPase 1
       5880 RAC2; Rac family small GTPase 2
       5881 RAC3; Rac family small GTPase 3
       23396 PIP5K1C; phosphatidylinositol-4-phosphate 5-kinase type 1 gamma
       8394 PIP5K1A; phosphatidylinositol-4-phosphate 5-kinase type 1 alpha
       8395 PIP5K1B; phosphatidylinositol-4-phosphate 5-kinase type 1 beta
       382 ARF6; ADP ribosylation factor 6
       8976 WASL; WASP like actin nucleation promoting factor
       10097 ACTR2; actin related protein 2
       57180 ACTR3B; actin related protein 3B
       653857 ACTR3C; actin related protein 3C
       10096 ACTR3; actin related protein 3
       10095 ARPC1B; actin related protein 2/3 complex subunit 1B
       10552 ARPC1A; actin related protein 2/3 complex subunit 1A
       10109 ARPC2; actin related protein 2/3 complex subunit 2
       10094 ARPC3; actin related protein 2/3 complex subunit 3
       10093 ARPC4; actin related protein 2/3 complex subunit 4
       10092 ARPC5; actin related protein 2/3 complex subunit 5
       81873 ARPC5L; actin related protein 2/3 complex subunit 5 like
       71 ACTG1; actin gamma 1
       60 ACTB; actin beta
       147179 WIPF2; WAS/WASL interacting protein family member 2
       7456 WIPF1; WAS/WASL interacting protein family member 1
       644150 WIPF3; WAS/WASL interacting protein family member 3
       10458 BAIAP2; BAR/IMD domain containing adaptor protein 2
       10163 WASF2; WASP family member 2
       5829 PXN; paxillin
       9815 GIT2; GIT ArfGAP 2
       8874 ARHGEF7; Rho guanine nucleotide exchange factor 7
       998 CDC42; cell division cycle 42
       7454 WAS; WASP actin nucleation promoting factor
       2776 GNAQ; G protein subunit alpha q
       23365 ARHGEF12; Rho guanine nucleotide exchange factor 12
       9138 ARHGEF1; Rho guanine nucleotide exchange factor 1
       64283 ARHGEF28; Rho guanine nucleotide exchange factor 28
       387 RHOA; ras homolog family member A
       6093 ROCK1; Rho associated coiled-coil containing protein kinase 1
       9475 ROCK2; Rho associated coiled-coil containing protein kinase 2
       2533 FYB1; FYN binding protein 1
       8935 SKAP2; src kinase associated phosphoprotein 2
       114548 NLRP3; NLR family pyrin domain containing 3
       58484 NLRC4; NLR family CARD domain containing 4
       5585 PKN1; protein kinase N1
       5586 PKN2; protein kinase N2
       6197 RPS6KA3; ribosomal protein S6 kinase A3
       6195 RPS6KA1; ribosomal protein S6 kinase A1
       6196 RPS6KA2; ribosomal protein S6 kinase A2
       27330 RPS6KA6; ribosomal protein S6 kinase A6
       4210 MEFV; MEFV innate immuity regulator, pyrin
       3984 LIMK1; LIM domain kinase 1
       29108 PYCARD; PYD and CARD domain containing
       834 CASP1; caspase 1
       3606 IL18; interleukin 18
       3553 IL1B; interleukin 1 beta
       7099 TLR4; toll like receptor 4
       4615 MYD88; MYD88 innate immune signal transduction adaptor
       51135 IRAK4; interleukin 1 receptor associated kinase 4
       3654 IRAK1; interleukin 1 receptor associated kinase 1
       7189 TRAF6; TNF receptor associated factor 6
       7186 TRAF2; TNF receptor associated factor 2
       10454 TAB1; TGF-beta activated kinase 1 (MAP3K7) binding protein 1
       23118 TAB2; TGF-beta activated kinase 1 (MAP3K7) binding protein 2
       6885 MAP3K7; mitogen-activated protein kinase kinase kinase 7
       8517 IKBKG; inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
       1147 CHUK; component of inhibitor of nuclear factor kappa B kinase complex
       3551 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
       4792 NFKBIA; NFKB inhibitor alpha
       4790 NFKB1; nuclear factor kappa B subunit 1
       5970 RELA; RELA proto-oncogene, NF-kB subunit
       5604 MAP2K1; mitogen-activated protein kinase kinase 1
       5605 MAP2K2; mitogen-activated protein kinase kinase 2
       5594 MAPK1; mitogen-activated protein kinase 1
       5595 MAPK3; mitogen-activated protein kinase 3
       5606 MAP2K3; mitogen-activated protein kinase kinase 3
       5608 MAP2K6; mitogen-activated protein kinase kinase 6
       5600 MAPK11; mitogen-activated protein kinase 11
       6300 MAPK12; mitogen-activated protein kinase 12
       5603 MAPK13; mitogen-activated protein kinase 13
       1432 MAPK14; mitogen-activated protein kinase 14
       6416 MAP2K4; mitogen-activated protein kinase kinase 4
       5609 MAP2K7; mitogen-activated protein kinase kinase 7
       5599 MAPK8; mitogen-activated protein kinase 8
       5602 MAPK10; mitogen-activated protein kinase 10
       5601 MAPK9; mitogen-activated protein kinase 9
       2353 FOS; Fos proto-oncogene, AP-1 transcription factor subunit
       3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit
       148022 TICAM1; toll like receptor adaptor molecule 1
       29110 TBK1; TANK binding kinase 1
       3661 IRF3; interferon regulatory factor 3
       7124 TNF; tumor necrosis factor
       3569 IL6; interleukin 6
       3576 CXCL8; C-X-C motif chemokine ligand 8
       3456 IFNB1; interferon beta 1
       5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
       5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
       5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
       5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
       5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
       8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
       207 AKT1; AKT serine/threonine kinase 1
       208 AKT2; AKT serine/threonine kinase 2
       10000 AKT3; AKT serine/threonine kinase 3
       2932 GSK3B; glycogen synthase kinase 3 beta
       6347 CCL2; C-C motif chemokine ligand 2
       920 CD4; CD4 molecule
       925 CD8A; CD8a molecule
       926 CD8B; CD8b molecule
       927 CD8B2; CD8b2 molecule
       3932 LCK; LCK proto-oncogene, Src family tyrosine kinase
       7535 ZAP70; zeta chain of T cell receptor associated protein kinase 70
       27040 LAT; linker for activation of T cells
       3937 LCP2; lymphocyte cytosolic protein 2
       10451 VAV3; vav guanine nucleotide exchange factor 3
       7409 VAV1; vav guanine nucleotide exchange factor 1
       7410 VAV2; vav guanine nucleotide exchange factor 2
       5335 PLCG1; phospholipase C gamma 1
       4772 NFATC1; nuclear factor of activated T cells 1
       4773 NFATC2; nuclear factor of activated T cells 2
       4775 NFATC3; nuclear factor of activated T cells 3
       3558 IL2; interleukin 2
       3586 IL10; interleukin 10
K05717 FN1; fibronectin 1
K06483 ITGA4; integrin alpha 4
K06484 ITGA5; integrin alpha 5
K05719 ITGB1; integrin beta 1
K07863 RHOG; Ras homolog gene family, member G
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
K05871 PTK2B; focal adhesion kinase 2 [EC:2.7.10.2]
K04438 CRK; C-crk adapter molecule crk
K04438 CRK; C-crk adapter molecule crk
K05726 BCAR1; breast cancer anti-estrogen resistance 1
K12366 ELMO1; engulfment and cell motility protein 1
K18985 ELMO2; engulfment and cell motility protein 2
K13708 DOCK1; dedicator of cytokinesis protein 1
K06856 IGH; immunoglobulin heavy chain
K06472 FCGR2A; low affinity immunoglobulin gamma Fc receptor II-a
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
K07941 ARF6; ADP-ribosylation factor 6
K23612 WASL; neural Wiskott-Aldrich syndrome protein
K17260 ACTR2; actin-related protein 2
K18584 ACTR3; actin-related protein 3
K18584 ACTR3; actin-related protein 3
K18584 ACTR3; actin-related protein 3
K05757 ARPC1A_B; actin related protein 2/3 complex, subunit 1A/1B
K05757 ARPC1A_B; actin related protein 2/3 complex, subunit 1A/1B
K05758 ARPC2; actin related protein 2/3 complex, subunit 2
K05756 ARPC3; actin related protein 2/3 complex, subunit 3
K05755 ARPC4; actin related protein 2/3 complex, subunit 4
K05754 ARPC5; actin related protein 2/3 complex, subunit 5
K05754 ARPC5; actin related protein 2/3 complex, subunit 5
K05692 ACTB_G1; actin beta/gamma 1
K05692 ACTB_G1; actin beta/gamma 1
K19475 WIPF; WAS/WASL-interacting protein
K19475 WIPF; WAS/WASL-interacting protein
K19475 WIPF; WAS/WASL-interacting protein
K05627 BAIAP2; BAI1-associated protein 2
K05748 WASF2; WAS protein family, member 2
K05760 PXN; paxillin
K12487 GIT2; G protein-coupled receptor kinase interactor 2
K13710 ARHGEF7; Rho guanine nucleotide exchange factor 7
K04393 CDC42; cell division control protein 42
K05747 WAS; Wiskott-Aldrich syndrome protein
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K07532 ARHGEF12; Rho guanine nucleotide exchange factor 12
K12330 ARHGEF1; Rho guanine nucleotide exchange factor 1
K21072 ARHGEF28; A-kinase anchor protein 28
K04513 RHOA; Ras homolog gene family, member A
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K17698 FYB; FYN binding protein
K23471 SKAP2; src kinase-associated phosphoprotein 2
K12800 NLRP3; NACHT, LRR and PYD domains-containing protein 3
K12805 NLRC4; NLR family CARD domain-containing protein 4
K06071 PKN1; serine/threonine-protein kinase N1 [EC:2.7.11.13]
K23691 PKN2; serine/threonine-protein kinase N2 [EC:2.7.11.13]
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K12803 MEFV; pyrin
K05743 LIMK1; LIM domain kinase 1 [EC:2.7.11.1]
K12799 PYCARD; apoptosis-associated speck-like protein containing a CARD
K01370 CASP1; caspase 1 [EC:3.4.22.36]
K05482 IL18; interleukin 18
K04519 IL1B; interleukin 1 beta
K10160 TLR4; toll-like receptor 4
K04729 MYD88; myeloid differentiation primary response protein MyD88
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K04403 MAP3K7IP1; TAK1-binding protein 1
K04404 MAP3K7IP2; TAK1-binding protein 2
K04427 MAP3K7; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04432 MAP2K3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04430 MAP2K4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04379 FOS; proto-oncogene protein c-fos
K04448 JUN; transcription factor AP-1
K05842 TRIF; toll-like receptor adapter molecule 1
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K05411 IRF3; interferon regulatory factor 3
K03156 TNF; tumor necrosis factor superfamily, member 2
K05405 IL6; interleukin 6
K10030 IL8; interleukin 8
K05415 IFNB; interferon beta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K14624 CCL2; C-C motif chemokine 2
K06454 CD4; T-cell surface glycoprotein CD4
K06458 CD8A; T-cell surface glycoprotein CD8 alpha chain
K06459 CD8B; T-cell surface glycoprotein CD8 beta chain
K06459 CD8B; T-cell surface glycoprotein CD8 beta chain
K05856 LCK; lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2]
K07360 ZAP70; tyrosine-protein kinase ZAP-70 [EC:2.7.10.2]
K07362 LAT; linker for activation of T cells
K07361 LCP2; lymphocyte cytosolic protein 2
K05730 VAV; guanine nucleotide exchange factor VAV
K05730 VAV; guanine nucleotide exchange factor VAV
K05730 VAV; guanine nucleotide exchange factor VAV
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K04446 NFATC1; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3; nuclear factor of activated T-cells, cytoplasmic 3
K05429 IL2; interleukin 2
K05443 IL10; interleukin 10
     05133 Pertussis [PATH:hsa05133]
     05134 Legionellosis [PATH:hsa05134]
     05150 Staphylococcus aureus infection [PATH:hsa05150]
     05152 Tuberculosis [PATH:hsa05152]
     05100 Bacterial invasion of epithelial cells [PATH:hsa05100]
 
   09172 Infectious disease: viral
 
   09174 Infectious disease: parasitic
 
   09175 Drug resistance: antimicrobial
 
   09176 Drug resistance: antineoplastic
 
 09180 Brite Hierarchies
 
 09190 Not Included in Pathway or Brite

[ KO | BRITE | KEGG2 | KEGG ]
Last updated: December 4, 2020