KEGG   PATHWAY: mleu05169
Entry
mleu05169                   Pathway                                
Name
Epstein-Barr virus infection - Mandrillus leucophaeus (drill)
Description
Epstein-Barr virus (EBV) is a gamma-herpes virus that widely infects human populations predominantly at an early age but remains mostly asymptomatic. EBV has been linked to a wide spectrum of human malignancies, including nasopharyngeal carcinoma and other hematologic cancers, like Hodgkin's lymphoma, Burkitt's lymphoma (BL), B-cell immunoblastic lymphoma in HIV patients, and posttransplant-associated lymphoproliferative diseases.  EBV has the unique ability to establish life-long latent infection in primary human B lymphocytes. During latent infection, EBV expresses a small subset of genes, including 6 nuclear antigens (EBNA-1, -2, -3A, -3B, -3C, and -LP), 3 latent membrane proteins (LMP-1, -2A, and -2B), 2 small noncoding RNAs (EBER-1 and 2). On the basis of these latent gene expression, three different latency patterns associated with the types of cancers are recognized.
Class
Human Diseases; Infectious disease: viral
Pathway map
mleu05169  Epstein-Barr virus infection
mleu05169

Organism
Mandrillus leucophaeus (drill) [GN:mleu]
Gene
105529635  CR2; complement receptor type 2 isoform X1 [KO:K04012]
105541382  CD19; B-lymphocyte antigen CD19 isoform X1 [KO:K06465]
105540228  HLA class II histocompatibility antigen, DP beta 1 chain isoform X1 [KO:K06752]
105540229  HLA class II histocompatibility antigen, DP alpha 1 chain-like [KO:K06752]
105540230  LOW QUALITY PROTEIN: RLA class II histocompatibility antigen, DP alpha-1 chain-like [KO:K06752]
105553177  HLA class II histocompatibility antigen, DQ alpha 1 chain isoform X1 [KO:K06752]
105540670  HLA class II histocompatibility antigen, DQ beta 1 chain isoform X1 [KO:K06752]
105536146  HLA class II histocompatibility antigen, DRB1-15 beta chain isoform X1 [KO:K06752]
105536147  HLA class II histocompatibility antigen, DRB1-4 beta chain-like [KO:K06752]
105536148  HLA class II histocompatibility antigen, DR beta 3 chain-like [KO:K06752]
105536618  mamu class II histocompatibility antigen, DR alpha chain isoform X1 [KO:K06752]
105537163  HLA class II histocompatibility antigen, DP beta 1 chain-like [KO:K06752]
105537709  HLA class II histocompatibility antigen, DQ alpha 2 chain [KO:K06752]
105537711  HLA class II histocompatibility antigen, DRB1-1 beta chain isoform X1 [KO:K06752]
105537712  HLA class II histocompatibility antigen, DQ beta 1 chain-like [KO:K06752]
105531108  HLA class II histocompatibility antigen, DP alpha 1 chain [KO:K06752]
105531110  HLA class II histocompatibility antigen, DO alpha chain isoform X1 [KO:K06752]
105531112  HLA class II histocompatibility antigen, DM beta chain isoform X1 [KO:K06752]
105531113  HLA class II histocompatibility antigen, DM alpha chain isoform X1 [KO:K06752]
105531120  HLA class II histocompatibility antigen, DO beta chain [KO:K06752]
105531121  HLA class II histocompatibility antigen, DP alpha 1 chain-like [KO:K06752]
105531455  TLR2; toll-like receptor 2 [KO:K10159]
105553429  MYD88; myeloid differentiation primary response protein MyD88 isoform X1 [KO:K04729]
105553446  IRAK4; interleukin-1 receptor-associated kinase 4 isoform X1 [KO:K04733] [EC:2.7.11.1]
105555370  IRAK1; interleukin-1 receptor-associated kinase 1 [KO:K04730] [EC:2.7.11.1]
105534673  TRAF6; TNF receptor-associated factor 6 [KO:K03175] [EC:2.3.2.27]
105538854  TAB1; TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 [KO:K04403]
105528775  TAB2; TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 [KO:K04404]
105542756  MAP3K7; mitogen-activated protein kinase kinase kinase 7 isoform X1 [KO:K04427] [EC:2.7.11.25]
105537745  CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [KO:K04467] [EC:2.7.11.10]
105554929  IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [KO:K07209] [EC:2.7.11.10]
105534277  IKBKG; LOW QUALITY PROTEIN: NF-kappa-B essential modulator [KO:K07210]
105550156  NFKBIA; NF-kappa-B inhibitor alpha isoform X1 [KO:K04734]
105548314  NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1 [KO:K02580]
105528449  RELA; transcription factor p65 isoform X1 [KO:K04735]
105554159  TNF; tumor necrosis factor [KO:K03156]
105534984  IL6; interleukin-6 isoform X1 [KO:K05405]
105539630  DDX58; probable ATP-dependent RNA helicase DDX58 [KO:K12646] [EC:5.6.2.6]
105535879  MAVS; mitochondrial antiviral-signaling protein isoform X1 [KO:K12648]
105547858  TRAF3; TNF receptor-associated factor 3 isoform X1 [KO:K03174]
105534224  TBK1; serine/threonine-protein kinase TBK1 [KO:K05410] [EC:2.7.11.10]
105554628  IKBKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [KO:K07211] [EC:2.7.11.10]
105549339  IRF7; interferon regulatory factor 7 isoform X1 [KO:K09447]
105528977  IRF3; interferon regulatory factor 3 isoform X1 [KO:K05411]
105533798  interferon alpha-1/13 [KO:K05414]
105533799  IFNA8; interferon alpha-8 [KO:K05414]
105533800  IFNA2; interferon alpha-2 [KO:K05414]
105537891  IFNA6; interferon alpha-6 [KO:K05414]
105537892  interferon alpha-14 [KO:K05414]
105537894  interferon alpha-17 isoform X1 [KO:K05414]
105545746  IFNB1; interferon beta [KO:K05415]
105546382  interferon alpha/beta receptor 1-like [KO:K05130]
105553144  IFNAR1; interferon alpha/beta receptor 1 [KO:K05130]
105546376  IFNAR2; interferon alpha/beta receptor 2 [KO:K05131]
105543512  JAK1; tyrosine-protein kinase JAK1 [KO:K11217] [EC:2.7.10.2]
105549798  TYK2; non-receptor tyrosine-protein kinase TYK2 isoform X1 [KO:K11219] [EC:2.7.10.2]
105535217  STAT1; signal transducer and activator of transcription 1-alpha/beta isoform X1 [KO:K11220]
105529948  STAT2; signal transducer and activator of transcription 2 isoform X1 [KO:K11221]
105532728  IRF9; interferon regulatory factor 9 [KO:K04693]
105530227  EIF2AK2; interferon-induced, double-stranded RNA-activated protein kinase isoform X1 [KO:K16195] [EC:2.7.11.1]
105552284  OAS1; 2'-5'-oligoadenylate synthase 1 isoform X1 [KO:K14216] [EC:2.7.7.84]
105552285  OAS3; 2'-5'-oligoadenylate synthase 3 [KO:K14216] [EC:2.7.7.84]
105552286  OAS2; 2'-5'-oligoadenylate synthase 2 [KO:K14216] [EC:2.7.7.84]
105529115  CXCL10; C-X-C motif chemokine 10 [KO:K12671]
105555167  ISG15; ubiquitin-like protein ISG15 [KO:K12159]
105552455  FAS; tumor necrosis factor receptor superfamily member 6 isoform X1 [KO:K04390]
105544509  FAS-associated death domain protein [KO:K02373]
105544531  FAS-associated death domain protein-like [KO:K02373]
105535422  CASP8; caspase-8 isoform X1 [KO:K04398] [EC:3.4.22.61]
105542917  BID; BH3-interacting domain death agonist isoform X1 [KO:K04726]
105540034  BCL2L11; bcl-2-like protein 11 isoform X1 [KO:K16341]
105535165  BCL2; apoptosis regulator Bcl-2 isoform X1 [KO:K02161]
105539167  BAX; apoptosis regulator BAX isoform X1 [KO:K02159]
105544178  BAK1; bcl-2 homologous antagonist/killer isoform X1 [KO:K14021]
105533249  cytochrome c-like [KO:K08738]
105553485  cytochrome c [KO:K08738]
105553918  cytochrome c-like [KO:K08738]
105549520  cytochrome c-like [KO:K08738]
105548296  APAF1; apoptotic protease-activating factor 1 isoform X1 [KO:K02084]
105549432  CASP9; caspase-9 isoform X1 [KO:K04399] [EC:3.4.22.62]
105552669  caspase-3-like [KO:K02187] [EC:3.4.22.56]
105553959  CASP3; caspase-3 [KO:K02187] [EC:3.4.22.56]
105533563  uncharacterized protein LOC105533563 [KO:K10785]
105546604  uncharacterized protein LOC105546604 [KO:K10785]
105546662  uncharacterized protein LOC105546662 [KO:K10785]
105546668  uncharacterized protein LOC105546668 [KO:K10785]
105528216  CD3E; T-cell surface glycoprotein CD3 epsilon chain [KO:K06451]
105528218  CD3G; LOW QUALITY PROTEIN: T-cell surface glycoprotein CD3 gamma chain [KO:K06452]
105528217  CD3D; T-cell surface glycoprotein CD3 delta chain isoform X1 [KO:K06450]
105539575  CD247; T-cell surface glycoprotein CD3 zeta chain isoform X1 [KO:K06453]
105543319  PSMC2; 26S protease regulatory subunit 7 [KO:K03061]
105535289  PSMC1; 26S protease regulatory subunit 4 isoform X1 [KO:K03062]
105542428  PSMC4; 26S protease regulatory subunit 6B isoform X1 [KO:K03063]
105553601  PSMC6; 26S protease regulatory subunit 10B [KO:K03064]
105554823  PSMC3; 26S protease regulatory subunit 6A isoform X1 [KO:K03065]
105551722  PSMC5; 26S protease regulatory subunit 8 isoform X1 [KO:K03066]
105541024  PSMD2; 26S proteasome non-ATPase regulatory subunit 2 [KO:K03028]
105552414  PSMD1; 26S proteasome non-ATPase regulatory subunit 1 isoform X1 [KO:K03032]
105553052  PSMD3; 26S proteasome non-ATPase regulatory subunit 3 [KO:K03033]
105553193  PSMD12; 26S proteasome non-ATPase regulatory subunit 12 isoform X1 [KO:K03035]
105548703  PSMD11; 26S proteasome non-ATPase regulatory subunit 11 [KO:K03036]
105539886  PSMD6; LOW QUALITY PROTEIN: 26S proteasome non-ATPase regulatory subunit 6 [KO:K03037]
105537186  PSMD7; 26S proteasome non-ATPase regulatory subunit 7 [KO:K03038]
105530811  PSMD13; 26S proteasome non-ATPase regulatory subunit 13 [KO:K03039]
105534732  PSMD4; 26S proteasome non-ATPase regulatory subunit 4 [KO:K03029]
105547714  PSMD14; 26S proteasome non-ATPase regulatory subunit 14 [KO:K03030]
105534582  PSMD8; 26S proteasome non-ATPase regulatory subunit 8 isoform X1 [KO:K03031]
105548358  ADRM1; proteasomal ubiquitin receptor ADRM1 isoform X1 [KO:K06691]
105535576  SHFM1; 26S proteasome complex subunit DSS1 isoform X1 [KO:K10881]
105531118  TAP1; LOW QUALITY PROTEIN: antigen peptide transporter 1 [KO:K05653] [EC:7.4.2.14]
105531116  TAP2; antigen peptide transporter 2 [KO:K05654] [EC:7.4.2.14]
105544168  TAPBP; tapasin isoform X1 [KO:K08058]
105549349  PDIA3; protein disulfide-isomerase A3 [KO:K08056] [EC:5.3.4.1]
105534939  LOW QUALITY PROTEIN: calreticulin-like [KO:K08057]
105550058  CALR; calreticulin [KO:K08057]
105533269  class I histocompatibility antigen, Gogo-OKO alpha chain [KO:K06751]
105540194  LOW QUALITY PROTEIN: HLA class I histocompatibility antigen, B-67 alpha chain-like [KO:K06751]
105553110  LOW QUALITY PROTEIN: patr class I histocompatibility antigen, alpha chain E [KO:K06751]
105533649  LOW QUALITY PROTEIN: HLA class I histocompatibility antigen, A-30 alpha chain-like [KO:K06751]
105533654  LOW QUALITY PROTEIN: HLA class I histocompatibility antigen, A-30 alpha chain-like [KO:K06751]
105541160  LOW QUALITY PROTEIN: HLA class I histocompatibility antigen, A-11 alpha chain-like [KO:K06751]
105554853  patr class I histocompatibility antigen, A-126 alpha chain-like isoform X1 [KO:K06751]
105535298  mamu class I histocompatibility antigen, alpha chain F isoform X1 [KO:K06751]
105536048  HLA class I histocompatibility antigen, B-14 alpha chain isoform X1 [KO:K06751]
105550871  HLA class I histocompatibility antigen, B-14 alpha chain-like [KO:K06751]
105550892  LOW QUALITY PROTEIN: uncharacterized protein LOC105550892 [KO:K06751]
105548183  B2M; beta-2-microglobulin isoform X1 [KO:K08055]
105545356  SNW1; SNW domain-containing protein 1 isoform X1 [KO:K06063]
105554108  SIN3A; paired amphipathic helix protein Sin3a isoform X1 [KO:K11644]
105532430  HDAC2; histone deacetylase 2 isoform X1 [KO:K06067] [EC:3.5.1.98]
105535063  HDAC1; histone deacetylase 1 isoform X1 [KO:K06067] [EC:3.5.1.98]
105545851  NCOR2; nuclear receptor corepressor 2 [KO:K06065]
105540574  SAP30L; histone deacetylase complex subunit SAP30L [KO:K19202]
105543903  SAP30; histone deacetylase complex subunit SAP30 isoform X1 [KO:K19202]
105548051  CIR1; corepressor interacting with RBPJ 1 [KO:K06066]
105552087  RBPJL; recombining binding protein suppressor of hairless-like protein isoform X1 [KO:K06053]
105528556  RBPJ; recombining binding protein suppressor of hairless isoform X1 [KO:K06053]
105540665  HES1; transcription factor HES-1 [KO:K06054]
105541135  FCER2; low affinity immunoglobulin epsilon Fc receptor isoform X1 [KO:K06468]
105538109  RUNX3; runt-related transcription factor 3 isoform X1 [KO:K09279]
105537628  MYC; myc proto-oncogene protein [KO:K04377]
105542598  USP7; ubiquitin carboxyl-terminal hydrolase 7 isoform X1 [KO:K11838] [EC:3.4.19.12]
105537114  MDM2; E3 ubiquitin-protein ligase Mdm2 isoform X1 [KO:K06643] [EC:2.3.2.27]
105549866  TP53; cellular tumor antigen p53 isoform X1 [KO:K04451]
105544234  CDKN1A; LOW QUALITY PROTEIN: cyclin-dependent kinase inhibitor 1 [KO:K06625]
105551969  GADD45B; growth arrest and DNA damage-inducible protein GADD45 beta isoform X1 [KO:K04402]
105535934  GADD45G; growth arrest and DNA damage-inducible protein GADD45 gamma [KO:K04402]
105550104  GADD45A; growth arrest and DNA damage-inducible protein GADD45 alpha isoform X1 [KO:K04402]
105554817  DDB2; DNA damage-binding protein 2 isoform X1 [KO:K10140]
105551317  POLK; DNA polymerase kappa [KO:K03511] [EC:2.7.7.7]
105536404  TRAF5; TNF receptor-associated factor 5 [KO:K09849]
105539923  PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
105552763  PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
105549588  PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform [KO:K00922] [EC:2.7.1.153]
105547376  PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta [KO:K02649]
105543389  PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
105531763  PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1 [KO:K02649]
105540494  AKT3; RAC-gamma serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
105541755  AKT1; RAC-alpha serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
105542359  AKT2; RAC-beta serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
105543832  MAP3K14; mitogen-activated protein kinase kinase kinase 14 [KO:K04466] [EC:2.7.11.25]
105535885  RELB; transcription factor RelB [KO:K09253]
105537783  NFKB2; nuclear factor NF-kappa-B p100 subunit isoform X1 [KO:K04469]
105551442  TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein [KO:K03171]
105534635  NFKBIB; NF-kappa-B inhibitor beta [KO:K02581]
105544355  NFKBIE; LOW QUALITY PROTEIN: NF-kappa-B inhibitor epsilon [KO:K05872]
105528792  MAP2K4; dual specificity mitogen-activated protein kinase kinase 4 isoform X1 [KO:K04430] [EC:2.7.12.2]
105541149  MAP2K7; dual specificity mitogen-activated protein kinase kinase 7 [KO:K04431] [EC:2.7.12.2]
105547365  MAPK8; mitogen-activated protein kinase 8 [KO:K04440] [EC:2.7.11.24]
105554734  MAPK10; mitogen-activated protein kinase 10 isoform X1 [KO:K04440] [EC:2.7.11.24]
105537274  MAPK9; mitogen-activated protein kinase 9 isoform X1 [KO:K04440] [EC:2.7.11.24]
105543266  TRAF2; TNF receptor-associated factor 2 [KO:K03173] [EC:2.3.2.27]
105542896  RIPK1; receptor-interacting serine/threonine-protein kinase 1 [KO:K02861] [EC:2.7.11.1]
105554627  MAP2K3; dual specificity mitogen-activated protein kinase kinase 3 isoform X1 [KO:K04432] [EC:2.7.12.2]
105544191  MAP2K6; dual specificity mitogen-activated protein kinase kinase 6 [KO:K04433] [EC:2.7.12.2]
105543603  MAPK11; mitogen-activated protein kinase 11 [KO:K04441] [EC:2.7.11.24]
105543619  MAPK12; mitogen-activated protein kinase 12 [KO:K04441] [EC:2.7.11.24]
105544221  MAPK14; mitogen-activated protein kinase 14 isoform X1 [KO:K04441] [EC:2.7.11.24]
105544400  MAPK13; mitogen-activated protein kinase 13 [KO:K04441] [EC:2.7.11.24]
105534921  JUN; transcription factor AP-1 [KO:K04448]
105553792  ENTPD1; ectonucleoside triphosphate diphosphohydrolase 1 isoform X1 [KO:K01510] [EC:3.6.1.5]
105542665  ENTPD3; ectonucleoside triphosphate diphosphohydrolase 3 isoform X1 [KO:K01510] [EC:3.6.1.5]
105543296  ENTPD8; ectonucleoside triphosphate diphosphohydrolase 8 isoform X1 [KO:K01510] [EC:3.6.1.5]
105542289  CD40; tumor necrosis factor receptor superfamily member 5 isoform X1 [KO:K03160]
105528692  CD44; CD44 antigen isoform X1 [KO:K06256]
105541493  ITGAL; integrin alpha-L [KO:K05718]
105554377  CD58; lymphocyte function-associated antigen 3 isoform X1 [KO:K06492]
105549786  ICAM1; intercellular adhesion molecule 1 isoform X1 [KO:K06490]
105530523  VIM; vimentin isoform X1 [KO:K07606]
105538539  TNFAIP3; tumor necrosis factor alpha-induced protein 3 isoform X1 [KO:K11859] [EC:3.4.19.12]
105547548  JAK3; tyrosine-protein kinase JAK3 [KO:K11218] [EC:2.7.10.2]
105552958  STAT3; signal transducer and activator of transcription 3 [KO:K04692]
105552072  LYN; tyrosine-protein kinase Lyn [KO:K05854] [EC:2.7.10.2]
105547549  SYK; tyrosine-protein kinase SYK [KO:K05855] [EC:2.7.10.2]
105544312  NEDD4; E3 ubiquitin-protein ligase NEDD4 [KO:K10591] [EC:2.3.2.26]
105551438  RAC1; ras-related C3 botulinum toxin substrate 1 [KO:K04392]
105546567  ras-related protein Rac1-like [KO:K04392]
105532929  putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8 [KO:K06856]
105532934  uncharacterized protein LOC105532934 [KO:K06856]
105535254  putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8 [KO:K06856]
105535256  LOW QUALITY PROTEIN: uncharacterized protein LOC105535256 [KO:K06856]
105548664  putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8 [KO:K06856]
105536925  putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8 [KO:K06856]
105537275  putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8 [KO:K06856]
105537413  uncharacterized protein LOC105537413 [KO:K06856]
105538227  putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8 [KO:K06856]
105528165  BTK; tyrosine-protein kinase BTK isoform X1 [KO:K07370] [EC:2.7.10.2]
105553912  BLNK; B-cell linker protein isoform X1 [KO:K07371]
105546817  PLCG2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 [KO:K05859] [EC:3.1.4.11]
105555423  SKP2; S-phase kinase-associated protein 2 isoform X1 [KO:K03875]
105549206  CDKN1B; cyclin-dependent kinase inhibitor 1B isoform X1 [KO:K06624]
105544506  CCND1; G1/S-specific cyclin-D1 [KO:K04503]
105551132  CCND2; G1/S-specific cyclin-D2 isoform X1 [KO:K10151]
105544297  CCND3; G1/S-specific cyclin-D3 isoform X1 [KO:K10152]
105545589  CDK4; cyclin-dependent kinase 4 isoform X1 [KO:K02089] [EC:2.7.11.22]
105552568  CDK6; cyclin-dependent kinase 6 [KO:K02091] [EC:2.7.11.22]
105551507  CCNA2; cyclin-A2 [KO:K06627]
105548801  CCNA1; cyclin-A1 [KO:K06627]
105538723  CCNE2; G1/S-specific cyclin-E2 isoform X1 [KO:K06626]
105550361  CCNE1; G1/S-specific cyclin-E1 isoform X1 [KO:K06626]
105531943  CDK2; cyclin-dependent kinase 2 isoform X1 [KO:K02206] [EC:2.7.11.22]
105552849  RB1; retinoblastoma-associated protein [KO:K06618]
105528432  E2F1; transcription factor E2F1 [KO:K17454]
105538086  E2F2; transcription factor E2F2 [KO:K09389]
105552485  E2F3; transcription factor E2F3 [KO:K06620]
Compound
C00076  Calcium cation
C01245  D-myo-Inositol 1,4,5-trisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
Reference
PMID:15510157
  Authors
Young LS, Rickinson AB.
  Title
Epstein-Barr virus: 40 years on.
  Journal
Nat Rev Cancer 4:757-68 (2004)
DOI:10.1038/nrc1452
Reference
PMID:21372216
  Authors
Saha A, Robertson ES
  Title
Epstein-Barr virus-associated B-cell lymphomas: pathogenesis and clinical outcomes.
  Journal
Clin Cancer Res 17:3056-63 (2011)
DOI:10.1158/1078-0432.CCR-10-2578
Reference
PMID:21429244
  Authors
Ning S
  Title
Innate immune modulation in EBV infection.
  Journal
Herpesviridae 2:1 (2011)
DOI:10.1186/2042-4280-2-1
Reference
PMID:28408983
  Authors
Stanfield BA, Luftig MA
  Title
Recent advances in understanding Epstein-Barr virus.
  Journal
F1000Res 6:386 (2017)
DOI:10.12688/f1000research.10591.1
Reference
PMID:24586164
  Authors
van Gent M, Braem SG, de Jong A, Delagic N, Peeters JG, Boer IG, Moynagh PN, Kremmer E, Wiertz EJ, Ovaa H, Griffin BD, Ressing ME
  Title
Epstein-Barr virus large tegument protein BPLF1 contributes to innate immune evasion through interference with toll-like receptor signaling.
  Journal
PLoS Pathog 10:e1003960 (2014)
DOI:10.1371/journal.ppat.1003960
Reference
PMID:23850008
  Authors
Rajsbaum R, Garcia-Sastre A
  Title
Viral evasion mechanisms of early antiviral responses involving regulation of ubiquitin pathways.
  Journal
Trends Microbiol 21:421-9 (2013)
DOI:10.1016/j.tim.2013.06.006
Reference
PMID:25704559
  Authors
Hoffmann HH, Schneider WM, Rice CM
  Title
Interferons and viruses: an evolutionary arms race of molecular interactions.
  Journal
Trends Immunol 36:124-38 (2015)
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PLoS Pathog 7:e1001275 (2011)
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Related
pathway
mleu03050  Proteasome
mleu04010  MAPK signaling pathway
mleu04020  Calcium signaling pathway
mleu04064  NF-kappa B signaling pathway
mleu04110  Cell cycle
mleu04115  p53 signaling pathway
mleu04210  Apoptosis
mleu04612  Antigen processing and presentation
mleu04620  Toll-like receptor signaling pathway
mleu04622  RIG-I-like receptor signaling pathway
mleu04630  JAK-STAT signaling pathway
mleu04662  B cell receptor signaling pathway
KO pathway
ko05169   
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