KEGG   PATHWAY: gmu04010
Entry
gmu04010                    Pathway                                
Name
MAPK signaling pathway - Girardinichthys multiradiatus (darkedged splitfin)
Description
The mitogen-activated protein kinase (MAPK) cascade is a highly conserved module that is involved in various cellular functions, including cell proliferation, differentiation and migration. Mammals express at least four distinctly regulated groups of MAPKs, extracellular signal-related kinases (ERK)-1/2, Jun amino-terminal kinases (JNK1/2/3), p38 proteins (p38alpha/beta/gamma/delta) and ERK5, that are activated by specific MAPKKs: MEK1/2 for ERK1/2, MKK3/6 for the p38, MKK4/7 (JNKK1/2) for the JNKs, and MEK5 for ERK5. Each MAPKK, however, can be activated by more than one MAPKKK, increasing the complexity and diversity of MAPK signalling. Presumably each MAPKKK confers responsiveness to distinct stimuli. For example, activation of ERK1/2 by growth factors depends on the MAPKKK c-Raf, but other MAPKKKs may activate ERK1/2 in response to pro-inflammatory stimuli.
Class
Environmental Information Processing; Signal transduction
Pathway map
gmu04010  MAPK signaling pathway
gmu04010

Other DBs
GO: 0000165
Organism
Girardinichthys multiradiatus (darkedged splitfin) [GN:gmu]
Gene
124864229  voltage-dependent P/Q-type calcium channel subunit alpha-1A-like [KO:K04344]
124862209  voltage-dependent P/Q-type calcium channel subunit alpha-1A-like [KO:K04344]
124868854  cacna1ab; calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, b isoform X1 [KO:K04344]
124877319  cacna1ba; calcium channel, voltage-dependent, N type, alpha 1B subunit, a [KO:K04849]
124872479  cacna1bb; voltage-dependent N-type calcium channel subunit alpha-1B [KO:K04849]
124882886  cacna1c; voltage-dependent L-type calcium channel subunit alpha-1C [KO:K04850]
124856470  cacna1da; calcium channel, voltage-dependent, L type, alpha 1D subunit, a [KO:K04851]
124869361  cacna1db; voltage-dependent L-type calcium channel subunit alpha-1D [KO:K04851]
124869796  voltage-dependent R-type calcium channel subunit alpha-1E-like isoform X1 [KO:K04852]
124873256  voltage-dependent R-type calcium channel subunit alpha-1E [KO:K04852]
124867625  cacna1fa; LOW QUALITY PROTEIN: voltage-dependent L-type calcium channel subunit alpha-1D [KO:K04853]
124868417  cacna1fb; calcium channel, voltage-dependent, L type, alpha 1F subunit isoform X1 [KO:K04853]
124875310  cacna1g; voltage-dependent T-type calcium channel subunit alpha-1G isoform X1 [KO:K04854]
124864225  voltage-dependent T-type calcium channel subunit alpha-1H-like [KO:K04855]
124862289  voltage-dependent T-type calcium channel subunit alpha-1H-like isoform X1 [KO:K04855]
124863112  voltage-dependent T-type calcium channel subunit alpha-1I-like [KO:K04856]
124884180  voltage-dependent T-type calcium channel subunit alpha-1H-like isoform X1 [KO:K04856]
124864946  voltage-dependent T-type calcium channel subunit alpha-1I-like [KO:K04856]
124867723  voltage-dependent T-type calcium channel subunit alpha-1I-like [KO:K04856]
124869521  dihydropyridine-sensitive L-type skeletal muscle calcium channel subunit alpha-1-like [KO:K04857]
124856582  voltage-dependent calcium channel subunit alpha-2/delta-1 [KO:K04858]
124882862  voltage-dependent calcium channel subunit alpha-2/delta-1-like isoform X1 [KO:K04858]
124856417  cacna2d2a; voltage-dependent calcium channel subunit alpha-2/delta-2a isoform X1 [KO:K04859]
124856889  cacna2d2b; voltage-dependent calcium channel subunit alpha-2/delta-2b isoform X1 [KO:K04859]
124856095  voltage-dependent calcium channel subunit alpha-2/delta-3-like isoform X1 [KO:K04860]
124872364  cacna2d3a; voltage-dependent calcium channel subunit alpha-2/delta-3 isoform X1 [KO:K04860]
124880417  voltage-dependent calcium channel subunit alpha-2/delta-4-like isoform X1 [KO:K04861]
124882654  cacna2d4a; voltage-dependent calcium channel subunit alpha-2/delta-4 isoform X1 [KO:K04861]
124862971  voltage-dependent L-type calcium channel subunit beta-1-like isoform X1 [KO:K04862]
124864790  voltage-dependent L-type calcium channel subunit beta-1-like isoform X1 [KO:K04862]
124857852  cacnb2a; voltage-dependent L-type calcium channel subunit beta-2a isoform X1 [KO:K04863]
124874440  cacnb3a; voltage-dependent L-type calcium channel subunit beta-3a isoform X1 [KO:K04864]
124874636  cacnb3b; voltage-dependent L-type calcium channel subunit beta-4 [KO:K04864]
124871371  cacnb4a; voltage-dependent L-type calcium channel subunit beta-4a isoform X1 [KO:K04865]
124861210  voltage-dependent L-type calcium channel subunit beta-4-like isoform X1 [KO:K04865]
124863179  voltage-dependent calcium channel gamma-1 subunit-like [KO:K04866]
124864625  voltage-dependent calcium channel gamma-1 subunit-like [KO:K04866]
124867833  voltage-dependent calcium channel gamma-1 subunit-like [KO:K04866]
124863749  voltage-dependent calcium channel gamma-2 subunit [KO:K04867]
124862256  voltage-dependent calcium channel gamma-2 subunit [KO:K04867]
124869086  voltage-dependent calcium channel gamma-2 subunit-like [KO:K04867]
124863167  voltage-dependent calcium channel gamma-3 subunit-like [KO:K04868]
124864081  voltage-dependent calcium channel gamma-3 subunit-like [KO:K04868]
124868864  cacng3a; voltage-dependent calcium channel gamma-3 subunit [KO:K04868]
124863101  voltage-dependent calcium channel gamma-4 subunit-like [KO:K04869]
124864560  voltage-dependent calcium channel gamma-4 subunit-like [KO:K04869]
124869117  cacng4b; calcium channel, voltage-dependent, gamma subunit 4b [KO:K04869]
124863221  voltage-dependent calcium channel gamma-5 subunit-like [KO:K04870]
124864789  voltage-dependent calcium channel gamma-5 subunit-like [KO:K04870]
124869119  voltage-dependent calcium channel gamma-5 subunit [KO:K04870]
124879023  voltage-dependent calcium channel gamma-6 subunit-like [KO:K04871]
124866257  cacng6b; voltage-dependent calcium channel gamma-6 subunit isoform X1 [KO:K04871]
124864343  cacng7b; voltage-dependent calcium channel gamma-7 subunit [KO:K04872]
124879579  cacng7a; calcium channel, voltage-dependent, gamma subunit 7a isoform X1 [KO:K04872]
124878749  voltage-dependent calcium channel gamma-4 subunit-like [KO:K04873]
124866183  cacng8b; voltage-dependent calcium channel gamma-4 subunit [KO:K04873]
124862895  cAMP-dependent protein kinase catalytic subunit alpha-like [KO:K04345] [EC:2.7.11.11]
124870299  prkacbb; protein kinase, cAMP-dependent, catalytic, beta b isoform X1 [KO:K04345] [EC:2.7.11.11]
124864749  cAMP-dependent protein kinase catalytic subunit alpha isoform X1 [KO:K04345] [EC:2.7.11.11]
124873964  prkacba; protein kinase, cAMP-dependent, catalytic, beta a isoform X1 [KO:K04345] [EC:2.7.11.11]
124869187  cAMP-dependent protein kinase catalytic subunit alpha-like [KO:K04345] [EC:2.7.11.11]
124862966  protein kinase C alpha type-like isoform X1 [KO:K02677] [EC:2.7.11.13]
124864797  protein kinase C alpha type-like isoform X1 [KO:K02677] [EC:2.7.11.13]
124867838  protein kinase C alpha type isoform X1 [KO:K02677] [EC:2.7.11.13]
124862727  protein kinase C beta type-like isoform X1 [KO:K19662] [EC:2.7.11.13]
124864744  protein kinase C beta type isoform X1 [KO:K19662] [EC:2.7.11.13]
124868119  protein kinase C beta type-like isoform X1 [KO:K19662] [EC:2.7.11.13]
124866124  prkcg; protein kinase C gamma type [KO:K19663] [EC:2.7.11.13]
124868741  gna12a; guanine nucleotide-binding protein subunit alpha-12a isoform X1 [KO:K04346]
124870546  gng12a; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12a isoform X1 [KO:K04347]
124864654  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7-like [KO:K04347]
124873390  gng12b; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 isoform X1 [KO:K04347]
124862323  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7-like [KO:K04347]
124876425  ppp3ca; serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X1 [KO:K04348] [EC:3.1.3.16]
124877765  ppp3cca; protein phosphatase 3, catalytic subunit, gamma isozyme, a isoform X1 [KO:K04348] [EC:3.1.3.16]
124872173  serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform-like isoform X1 [KO:K04348] [EC:3.1.3.16]
124880271  serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X1 [KO:K04348] [EC:3.1.3.16]
124860843  ppp3cb; serine/threonine-protein phosphatase 2B catalytic subunit beta isoform isoform X1 [KO:K04348] [EC:3.1.3.16]
124859160  ppp3r1a; calcineurin subunit B type 1 [KO:K06268]
124869025  ppp3r1b; calcineurin subunit B type 1b [KO:K06268]
124856944  rasgrf1; ras-specific guanine nucleotide-releasing factor 1 [KO:K04349]
124867205  ras-specific guanine nucleotide-releasing factor 1-like [KO:K04349]
124877720  rasgrf2b; ras-specific guanine nucleotide-releasing factor 2 isoform X1 [KO:K12326]
124872078  rasgrf2a; ras-specific guanine nucleotide-releasing factor 2 [KO:K12326]
124855519  RAS guanyl-releasing protein 1-like isoform X1 [KO:K04350]
124883903  rasgrp4; RAS guanyl-releasing protein 4 [KO:K04350]
124880556  RAS guanyl-releasing protein 2-like isoform X1 [KO:K12361]
124859535  rasgrp3; ras guanyl-releasing protein 3 isoform X1 [KO:K12362]
124860141  rapgef2b; rap guanine nucleotide exchange factor 2 [KO:K08018]
124883857  nf1a; neurofibromin isoform X1 [KO:K08052]
124877788  rasa1a; ras GTPase-activating protein 1 [KO:K04352]
124883928  rasa2; ras GTPase-activating protein 2 [KO:K08053]
124856820  ras-related protein Rap-1A [KO:K04353]
124875123  ras-related protein Rap-1b [KO:K04353]
124882697  ras-related protein Rap-1b [KO:K07836]
124860567  egf; pro-epidermal growth factor [KO:K04357]
124856394  tgfa; protransforming growth factor alpha [KO:K08774]
124877462  proepiregulin-like [KO:K09784]
124876079  putative fibroblast growth factor 1 [KO:K18496]
124860400  fgf1a; putative fibroblast growth factor 1 [KO:K18496]
124859969  fgf2; fibroblast growth factor 2 [KO:K18497]
124878304  fgf10b; fibroblast growth factor 10b [KO:K04358]
124878354  fgf5; fibroblast growth factor 5 [KO:K04358]
124878372  fgf17; fibroblast growth factor 17 [KO:K04358]
124866643  fgf4; fibroblast growth factor 4 [KO:K04358]
124872739  fgf10a; fibroblast growth factor 10a [KO:K04358]
124859436  fgf8a; fibroblast growth factor 8 isoform X1 [KO:K04358]
124879774  fibroblast growth factor 4-like [KO:K04358]
124859958  fgf16; fibroblast growth factor 16 [KO:K04358]
124859959  fgf24; fibroblast growth factor 24 [KO:K04358]
124867365  fgf3; fibroblast growth factor 3 [KO:K04358]
124867394  fgf7; fibroblast growth factor 7 [KO:K04358]
124860129  fgf18a; fibroblast growth factor 18a isoform X1 [KO:K04358]
124860337  fgf20b; fibroblast growth factor 20b [KO:K04358]
124873990  fgf22; fibroblast growth factor 22 [KO:K04358]
124867871  fgf8b; fibroblast growth factor 8b [KO:K04358]
124861226  fibroblast growth factor 4B-like isoform X1 [KO:K04358]
124868764  fibroblast growth factor 20-like [KO:K04358]
124882677  fibroblast growth factor 6-like [KO:K04358]
124867273  fgf19; fibroblast growth factor 19 [KO:K22603]
124874935  fgf21; fibroblast growth factor 21 [KO:K22429]
124882673  fgf23; fibroblast growth factor 23 [KO:K22428]
124857129  ngfb; nerve growth factor [KO:K02582]
124865727  ngfa; neurotrophin-7 [KO:K02582]
124866445  bdnf; brain-derived neurotrophic factor isoform X1 [KO:K04355]
124882762  ntf3; neurotrophin-3 isoform X1 [KO:K04356]
124860812  insb; preproinsulin b [KO:K04526]
124875874  ins; insulin isoform X1 [KO:K04526]
124876646  igf3; insulin-like growth factor 3 [KO:K05459]
124883008  igf1; insulin-like growth factor I isoform X1 [KO:K05459]
124856566  igf2b; insulin-like growth factor 2b [KO:K13769]
124863463  platelet-derived growth factor subunit A-like isoform X1 [KO:K04359]
124863714  platelet-derived growth factor subunit A-like isoform X1 [KO:K04359]
124867911  platelet-derived growth factor subunit A-like [KO:K04359]
124869167  si:ch211-79m20.1; uncharacterized protein si:ch211-79m20.1 [KO:K17386]
124883537  pdgfd; platelet-derived growth factor D [KO:K05450]
124859797  pdgfc; platelet-derived growth factor C [KO:K05450]
124883160  uncharacterized protein LOC124883160 isoform X1 [KO:K05461]
124859373  kitlga; kit ligand a isoform X1 [KO:K05461]
124860596  vegfba; vascular endothelial growth factor B isoform X1 [KO:K05448]
124882425  vegfab; vascular endothelial growth factor Ab isoform X1 [KO:K05448]
124856012  pgfb; placenta growth factor isoform X1 [KO:K16859]
124882351  pgfa; vascular endothelial growth factor A isoform X1 [KO:K16859]
124867445  vegfd; vascular endothelial growth factor D [KO:K05449]
124867938  vegfc; vascular endothelial growth factor C isoform X1 [KO:K05449]
124861298  vascular endothelial growth factor C-like [KO:K05449]
124857843  hepatocyte growth factor [KO:K05460]
124882706  hgfa; hepatocyte growth factor a isoform X1 [KO:K05460]
124857045  angpt4; angiopoietin-1 [KO:K05465]
124879037  angpt2b; angiopoietin-2b [KO:K05466]
124859454  angpt2a; angiopoietin-2a [KO:K05466]
124855994  efna2a; ephrin-A2 isoform X1 [KO:K05462]
124877152  efna5b; ephrin-A5b isoform X1 [KO:K05462]
124865438  efna3b; ephrin-A3b isoform X1 [KO:K05462]
124872422  ephrin-A5b-like isoform X1 [KO:K05462]
124878872  efna3a; ephrin-A3 isoform X1 [KO:K05462]
124866348  si:dkey-246i14.3; ephrin-A4 [KO:K05462]
124879961  ephrin-A1-like isoform X1 [KO:K05462]
124873943  ephrin-A2-like [KO:K05462]
124862626  efna1b; ephrin-A1b [KO:K05462]
124878290  glial cell line-derived neurotrophic factor-like [KO:K05452]
124872813  gdnfa; glial cell line-derived neurotrophic factor [KO:K05452]
124870027  neurturin-like [KO:K25414]
124870440  glial cell line-derived neurotrophic factor [KO:K25415]
124868622  persephin [KO:K25416]
124858134  melanoma receptor tyrosine-protein kinase-like isoform X1 [KO:K04361] [EC:2.7.10.1]
124869445  egfra; epidermal growth factor receptor [KO:K04361] [EC:2.7.10.1]
124875242  erbb2; receptor tyrosine-protein kinase erbB-2 [KO:K05083] [EC:2.7.10.1]
124857405  erbb3a; receptor tyrosine-protein kinase erbB-3a isoform X1 [KO:K05084] [EC:2.7.10.1]
124874066  erbb3b; receptor tyrosine-protein kinase erbB-3b isoform X1 [KO:K05084] [EC:2.7.10.1]
124871474  receptor tyrosine-protein kinase erbB-4-like [KO:K05085] [EC:2.7.10.1]
124861969  receptor tyrosine-protein kinase erbB-4-like [KO:K05085] [EC:2.7.10.1]
124877368  fgfr1a; fibroblast growth factor receptor 1-A isoform X1 [KO:K04362] [EC:2.7.10.1]
124883651  si:ch211-167j9.5; tyrosine kinase receptor Cad96Ca [KO:K05093] [EC:2.7.10.1]
124859662  fgfr2; fibroblast growth factor receptor 2 isoform X1 [KO:K05093] [EC:2.7.10.1]
124855142  fgfr3; fibroblast growth factor receptor 3 isoform X1 [KO:K05094] [EC:2.7.10.1]
124876448  fgfr4; fibroblast growth factor receptor 4 [KO:K05095] [EC:2.7.10.1]
124863115  tumor necrosis factor receptor superfamily member 16-like [KO:K02583]
124865036  tumor necrosis factor receptor superfamily member 16-like [KO:K02583]
124866368  nradd; tumor necrosis factor receptor superfamily member 16 [KO:K02583]
124875531  ngfrb; nerve growth factor receptor b [KO:K02583]
124865367  ntrk1; high affinity nerve growth factor receptor isoform X1 [KO:K03176] [EC:2.7.10.1]
124878106  ntrk2a; neurotrophic tyrosine kinase, receptor, type 2a isoform X1 [KO:K04360] [EC:2.7.10.1]
124872807  ntrk2b; neurotrophic tyrosine kinase, receptor, type 2b [KO:K04360] [EC:2.7.10.1]
124869846  insra; insulin receptor a [KO:K04527] [EC:2.7.10.1]
124874283  insrb; insulin receptor b [KO:K04527] [EC:2.7.10.1]
124885065  igf1ra; insulin-like growth factor 1a receptor [KO:K05087] [EC:2.7.10.1]
124866795  insulin-like growth factor 1 receptor [KO:K05087] [EC:2.7.10.1]
124873707  pdgfra; platelet-derived growth factor receptor alpha [KO:K04363] [EC:2.7.10.1]
124876578  platelet-derived growth factor receptor beta-like [KO:K05089] [EC:2.7.10.1]
124860432  pdgfrb; platelet-derived growth factor receptor beta [KO:K05089] [EC:2.7.10.1]
124876382  csf1rb; macrophage colony-stimulating factor 1 receptor 2 [KO:K05090] [EC:2.7.10.1]
124860904  csf1ra; macrophage colony-stimulating factor 1 receptor [KO:K05090] [EC:2.7.10.1]
124874526  kita; mast/stem cell growth factor receptor kita isoform X1 [KO:K05091] [EC:2.7.10.1]
124868634  kitb; KIT proto-oncogene, receptor tyrosine kinase b isoform X1 [KO:K05091] [EC:2.7.10.1]
124857939  flt3; receptor-type tyrosine-protein kinase FLT3 [KO:K05092] [EC:2.7.10.1]
124858000  flt1; vascular endothelial growth factor receptor 1 isoform X1 [KO:K05096] [EC:2.7.10.1]
124860351  kdrl; vascular endothelial growth factor receptor kdr-like isoform X1 [KO:K05096] [EC:2.7.10.1]
124860198  flt4; vascular endothelial growth factor receptor 3 [KO:K05097] [EC:2.7.10.1]
124874157  kdr; vascular endothelial growth factor receptor 2 [KO:K05098] [EC:2.7.10.1]
124858154  met; hepatocyte growth factor receptor isoform X1 [KO:K05099] [EC:2.7.10.1]
124857252  epha2a; ephrin type-A receptor 2a [KO:K05103] [EC:2.7.10.1]
124872475  epha2b; ephrin type-A receptor 2 [KO:K05103] [EC:2.7.10.1]
124858614  ret; proto-oncogene tyrosine-protein kinase receptor Ret [KO:K05126] [EC:2.7.10.1]
124863357  growth factor receptor-bound protein 2 [KO:K04364]
124863971  growth factor receptor-bound protein 2 [KO:K04364]
124868143  son of sevenless homolog 1-like isoform X1 [KO:K03099]
124855236  sos2; son of sevenless homolog 2 [KO:K03099]
124882413  GTPase HRas [KO:K02833]
124863530  GTPase KRas-like isoform X1 [KO:K07827]
124864335  GTPase KRas-like isoform X1 [KO:K07827]
124879131  kras; GTPase KRas isoform X1 [KO:K07827]
124862859  ras-related protein R-Ras2-like [KO:K07830]
124864555  ras-related protein R-Ras2-like [KO:K07830]
124866950  rras2; ras-related protein R-Ras2 [KO:K07830]
124871430  mrasa; ras-related protein M-Ras [KO:K07831]
124878222  araf; serine/threonine-protein kinase A-Raf [KO:K08845] [EC:2.7.11.1]
124883025  braf; serine/threonine-protein kinase B-raf isoform X1 [KO:K04365] [EC:2.7.11.1]
124866030  raf1a; raf-1 proto-oncogene, serine/threonine kinase a isoform X1 [KO:K04366] [EC:2.7.11.1]
124856513  map2k1; dual specificity mitogen-activated protein kinase kinase 1 [KO:K04368] [EC:2.7.12.2]
124874089  map2k2a; dual specificity mitogen-activated protein kinase kinase 2a [KO:K04369] [EC:2.7.12.2]
124884896  lamtor3; ragulator complex protein LAMTOR3 [KO:K04370]
124863274  mitogen-activated protein kinase 1-like [KO:K04371] [EC:2.7.11.24]
124864295  mitogen-activated protein kinase 1-like [KO:K04371] [EC:2.7.11.24]
124877799  mapk1; mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
124873971  mknk2b; MAP kinase-interacting serine/threonine-protein kinase 2b [KO:K04372] [EC:2.7.11.1]
124874316  mknk1; MAP kinase-interacting serine/threonine-protein kinase 1 [KO:K04372] [EC:2.7.11.1]
124855459  rps6ka1; ribosomal protein S6 kinase alpha-1 isoform X1 [KO:K04373] [EC:2.7.11.1]
124858144  rps6ka3b; ribosomal protein S6 kinase alpha-3 isoform X1 [KO:K04373] [EC:2.7.11.1]
124860006  rps6kal; ribosomal protein S6 kinase alpha-6 [KO:K04373] [EC:2.7.11.1]
124867611  rps6ka2; ribosomal protein S6 kinase alpha-2 [KO:K04373] [EC:2.7.11.1]
124863824  cyclic AMP-dependent transcription factor ATF-4-like [KO:K04374]
124869150  atf4a; cyclic AMP-dependent transcription factor ATF-4 [KO:K04374]
124868529  elk1; ETS domain-containing protein Elk-1 isoform X1 [KO:K04375]
124857059  elk4; ETS domain-containing protein Elk-4 isoform X1 [KO:K04376]
124869726  transcriptional regulator Myc-B-like [KO:K04377]
124858439  myca; transcriptional regulator Myc-A isoform X1 [KO:K04377]
124856963  mych; myelocytomatosis oncogene homolog [KO:K04377]
124858656  srfb; serum response factor b isoform X1 [KO:K04378]
124869151  serum response factor-like isoform X1 [KO:K04378]
124884856  fosaa; protein c-Fos isoform X1 [KO:K04379]
124881577  protein c-Fos-like [KO:K04379]
124881628  protein c-Fos-like isoform X1 [KO:K04379]
124863694  microtubule-associated protein tau-like [KO:K04380]
124874943  microtubule-associated protein tau-like isoform X1 [KO:K04380]
124862214  microtubule-associated protein tau-like [KO:K04380]
124878785  stathmin-like [KO:K04381]
124865886  stmn1b; stathmin 1b [KO:K04381]
124874186  pla2g4ab; cytosolic phospholipase A2 [KO:K16342] [EC:3.1.1.4]
124879956  tnfa; tumor necrosis factor a (TNF superfamily, member 2) isoform X1 [KO:K03156]
124877334  interleukin-1 beta-like [KO:K04519]
124877353  interleukin-1 beta-like [KO:K04519]
124884769  tgfb1a; transforming growth factor, beta 1a [KO:K13375]
124860909  tgfb5; transforming growth factor beta-2 proprotein [KO:K13376]
124882556  transforming growth factor beta-3 proprotein-like [KO:K13377]
124855346  tgfb3; transforming growth factor beta-3 proprotein [KO:K13377]
124862998  si:ch211-112c15.8; tumor necrosis factor receptor superfamily member 1A isoform X1 [KO:K03158]
124866320  tnfrsf1a; tumor necrosis factor receptor superfamily member 1A [KO:K03158]
124871075  interleukin-1 receptor type 1 isoform X1 [KO:K04386]
124884583  interleukin-1 receptor accessory protein [KO:K04723]
124858107  tgfbr1b; TGF-beta receptor type-1b isoform X1 [KO:K04674] [EC:2.7.11.30]
124871723  tgfbr2l; TGF-beta receptor type-2 [KO:K04388] [EC:2.7.11.30]
124865875  tgfbr2b; TGF-beta receptor type-2 isoform X1 [KO:K04388] [EC:2.7.11.30]
124879943  TGF-beta receptor type-2-like [KO:K04388] [EC:2.7.11.30]
124860047  cd40lg; CD40 ligand [KO:K04389]
124874253  faslg; tumor necrosis factor ligand superfamily member 6 [KO:K04389]
124858714  tumor necrosis factor receptor superfamily member 6-like [KO:K04390]
124863148  ras-related C3 botulinum toxin substrate 1 [KO:K04392]
124864617  ras-related C3 botulinum toxin substrate 1-like [KO:K04392]
124874627  ras-related C3 botulinum toxin substrate 1-like [KO:K04392]
124875407  ras-related C3 botulinum toxin substrate 1-like [KO:K04392]
124869199  rac2; ras-related C3 botulinum toxin substrate 2 [KO:K07860]
124875062  rac3b; ras-related C3 botulinum toxin substrate 3b isoform X1 [KO:K07861]
124856632  cell division control protein 42 homolog [KO:K04393]
124865607  cell division control protein 42 homolog [KO:K04393]
124865608  cell division control protein 42 homolog [KO:K04393]
124879429  cell division control protein 42 homolog [KO:K04393]
124867548  cell division control protein 42 homolog isoform X1 [KO:K04393]
124866713  tradd; tumor necrosis factor receptor type 1-associated DEATH domain protein isoform X1 [KO:K03171]
124860636  caspase-3-like [KO:K02187] [EC:3.4.22.56]
124868646  casp3a; caspase-3a isoform X1 [KO:K02187] [EC:3.4.22.56]
124878632  TNF receptor-associated factor 2-like isoform X1 [KO:K03173] [EC:2.3.2.27]
124872818  TNF receptor-associated factor 2-like [KO:K03173] [EC:2.3.2.27]
124872824  traf2b; TNF receptor-associated factor 2 isoform X1 [KO:K03173] [EC:2.3.2.27]
124879571  daxx; death domain-associated protein 6 isoform X1 [KO:K02308]
124857967  myd88; myeloid differentiation primary response protein MyD88 [KO:K04729]
124875456  irak1; interleukin-1 receptor-associated kinase 1 isoform X1 [KO:K04730] [EC:2.7.11.1]
124884703  irak4; interleukin-1 receptor-associated kinase 4 isoform X1 [KO:K04733] [EC:2.7.11.1]
124866796  traf6; TNF receptor-associated factor 6 isoform X1 [KO:K03175] [EC:2.3.2.27]
124878122  gadd45ga; growth arrest and DNA-damage-inducible, gamma a [KO:K04402]
124872760  growth arrest and DNA damage-inducible protein GADD45 gamma-like [KO:K04402]
124874088  gadd45ab; growth arrest and DNA-damage-inducible, alpha, b [KO:K04402]
124874093  gadd45ba; growth arrest and DNA-damage-inducible, beta a [KO:K04402]
124855275  growth arrest and DNA damage-inducible protein GADD45 beta-like [KO:K04402]
124869433  gadd45aa; growth arrest and DNA-damage-inducible, alpha, a isoform X1 [KO:K04402]
124869146  tab1; TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 isoform X1 [KO:K04403]
124881924  tab2; TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 isoform X1 [KO:K04404]
124880454  ecsit; evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial [KO:K04405]
124858809  mitogen-activated protein kinase kinase kinase kinase 3-like [KO:K04406] [EC:2.7.11.1]
124871084  map4k4; traf2 and NCK-interacting protein kinase [KO:K04407] [EC:2.7.11.1]
124860117  si:zfos-2326c3.2; mitogen-activated protein kinase kinase kinase kinase 4 isoform X1 [KO:K04407] [EC:2.7.11.1]
124861334  mitogen-activated protein kinase kinase kinase kinase 4-like isoform X1 [KO:K04407] [EC:2.7.11.1]
124855774  serine/threonine-protein kinase PAK 2-like [KO:K04410] [EC:2.7.11.1]
124873465  pak2b; serine/threonine-protein kinase PAK 2b [KO:K04410] [EC:2.7.11.1]
124857302  serine/threonine-protein kinase 4-like isoform X1 [KO:K04411]
124878985  stk3; serine/threonine-protein kinase 3 [KO:K04412]
124880536  map4k2; mitogen-activated protein kinase kinase kinase kinase 2 isoform X1 [KO:K04414] [EC:2.7.11.1]
124857687  map3k8; mitogen-activated protein kinase kinase kinase 8 [KO:K04415] [EC:2.7.11.25]
124880274  mitogen-activated protein kinase kinase kinase 11 [KO:K04419] [EC:2.7.11.25]
124861929  map3k2; mitogen-activated protein kinase kinase kinase 2 [KO:K04420] [EC:2.7.11.25]
124863354  mitogen-activated protein kinase kinase kinase 3-like [KO:K04421] [EC:2.7.11.25]
124864760  mitogen-activated protein kinase kinase kinase 3-like [KO:K04421] [EC:2.7.11.25]
124858048  map3k22; mitogen-activated protein kinase kinase kinase 22 [KO:K04421] [EC:2.7.11.25]
124855259  map3k9; mitogen-activated protein kinase kinase kinase 9 isoform X1 [KO:K04417] [EC:2.7.11.25]
124883831  map3k10; mitogen-activated protein kinase kinase kinase 10 [KO:K04418] [EC:2.7.11.25]
124859216  map3k21; mitogen-activated protein kinase kinase kinase 21 isoform X1 [KO:K17534] [EC:2.7.11.25]
124856295  mitogen-activated protein kinase kinase kinase 12-like [KO:K04423] [EC:2.7.11.25]
124865267  map3k12; mitogen-activated protein kinase kinase kinase 12 [KO:K04423] [EC:2.7.11.25]
124871422  si:ch211-45c16.2; mitogen-activated protein kinase kinase kinase 13 [KO:K04422] [EC:2.7.11.25]
124869998  probable serine/threonine-protein kinase roco7 [KO:K04424] [EC:2.7.11.25]
124871582  zak; mitogen-activated protein kinase kinase kinase 20 [KO:K04424] [EC:2.7.11.25]
124882075  map3k5; mitogen-activated protein kinase kinase kinase 5 [KO:K04426] [EC:2.7.11.25]
124862290  si:ch211-1i11.3; mitogen-activated protein kinase kinase kinase 5 [KO:K04426] [EC:2.7.11.25]
124855438  mitogen-activated protein kinase kinase kinase 7-like isoform X1 [KO:K04427] [EC:2.7.11.25]
124881860  map3k7; mitogen-activated protein kinase kinase kinase 7 isoform X1 [KO:K04427] [EC:2.7.11.25]
124859256  map3k4; mitogen-activated protein kinase kinase kinase 4 isoform X1 [KO:K04428] [EC:2.7.11.25]
124876087  taok1b; serine/threonine-protein kinase TAO1 [KO:K04429] [EC:2.7.11.1]
124863905  serine/threonine-protein kinase TAO2-like isoform X1 [KO:K04429] [EC:2.7.11.1]
124884091  taok1a; serine/threonine-protein kinase TAO1 [KO:K04429] [EC:2.7.11.1]
124877996  taok3a; serine/threonine-protein kinase TAO3 isoform X1 [KO:K04429] [EC:2.7.11.1]
124872066  taok3b; serine/threonine-protein kinase TAO3 [KO:K04429] [EC:2.7.11.1]
124874948  taok2b; serine/threonine-protein kinase TAO2 isoform X1 [KO:K04429] [EC:2.7.11.1]
124862413  serine/threonine-protein kinase TAO2-like isoform X1 [KO:K04429] [EC:2.7.11.1]
124862979  dual specificity mitogen-activated protein kinase kinase 4-like isoform X1 [KO:K04430] [EC:2.7.12.2]
124864757  dual specificity mitogen-activated protein kinase kinase 4-like isoform X1 [KO:K04430] [EC:2.7.12.2]
124875573  map2k4b; dual specificity mitogen-activated protein kinase kinase 4b isoform X1 [KO:K04430] [EC:2.7.12.2]
124868478  map2k7; dual specificity mitogen-activated protein kinase kinase 7 isoform X1 [KO:K04431] [EC:2.7.12.2]
124862863  dual specificity mitogen-activated protein kinase kinase 6-like [KO:K04433] [EC:2.7.12.2]
124864761  dual specificity mitogen-activated protein kinase kinase 6-like isoform X1 [KO:K04433] [EC:2.7.12.2]
124875121  map2k6; dual specificity mitogen-activated protein kinase kinase 6 [KO:K04433] [EC:2.7.12.2]
124867257  C-Jun-amino-terminal kinase-interacting protein 1-like isoform X1 [KO:K04434]
124855152  C-Jun-amino-terminal kinase-interacting protein 1-like [KO:K04434]
124881828  mapk8ip2; C-Jun-amino-terminal kinase-interacting protein 2 isoform X1 [KO:K04435]
124863202  LOW QUALITY PROTEIN: C-Jun-amino-terminal kinase-interacting protein 3-like [KO:K04436]
124864123  C-Jun-amino-terminal kinase-interacting protein 3-like isoform X1 [KO:K04436]
124875603  flna; filamin-A isoform X1 [KO:K04437]
124876940  adapter molecule crk-like [KO:K04438]
124884098  crk; adapter molecule crk [KO:K04438]
124872914  crkl; crk-like protein isoform X1 [KO:K04438]
124876273  arrestin red cell [KO:K04439]
124884170  arrb1; beta-arrestin-1 [KO:K04439]
124872468  mapk10; mitogen-activated protein kinase 10 isoform X1 [KO:K04440] [EC:2.7.11.24]
124859135  mapk8a; mitogen-activated protein kinase 8 [KO:K04440] [EC:2.7.11.24]
124860150  mapk9; mitogen-activated protein kinase 9 isoform X1 [KO:K04440] [EC:2.7.11.24]
124875307  mapk8b; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
124857113  mapk14b; mitogen-activated protein kinase 14B isoform X1 [KO:K04441] [EC:2.7.11.24]
124871744  zgc:171775; STKc_p38 domain-containing protein [KO:K04441] [EC:2.7.11.24]
124872081  mapk13; mitogen-activated protein kinase 13 [KO:K04441] [EC:2.7.11.24]
124858438  mapk12a; mitogen-activated protein kinase 12 isoform X1 [KO:K04441] [EC:2.7.11.24]
124868188  mapk14a; mitogen-activated protein kinase 14A [KO:K04441] [EC:2.7.11.24]
124882732  mitogen-activated protein kinase 12-like [KO:K04441] [EC:2.7.11.24]
124882947  mapk11; mitogen-activated protein kinase 11 isoform X1 [KO:K04441] [EC:2.7.11.24]
124878519  mapkapk5; MAP kinase-activated protein kinase 5 isoform X1 [KO:K04442] [EC:2.7.11.1]
124857538  mapkapk2a; MAP kinase-activated protein kinase 2 [KO:K04443] [EC:2.7.11.1]
124856272  MAP kinase-activated protein kinase 2-like [KO:K04444] [EC:2.7.11.1]
124857349  mapkapk3; MAP kinase-activated protein kinase 3 [KO:K04444] [EC:2.7.11.1]
124855541  rps6ka5; ribosomal protein S6 kinase alpha-5 [KO:K04445] [EC:2.7.11.1]
124875940  rps6ka4; ribosomal protein S6 kinase alpha-4 [KO:K16510] [EC:2.7.11.1]
124855992  cdc25b; M-phase inducer phosphatase 2 [KO:K05866] [EC:3.1.3.48]
124864120  nuclear factor of activated T-cells, cytoplasmic 1-like isoform X1 [KO:K04446]
124879442  nfatc1; nuclear factor of activated T-cells, cytoplasmic 1 isoform X1 [KO:K04446]
124858913  nuclear factor of activated T-cells, cytoplasmic 3-like [KO:K17333]
124867144  nfatc3a; nuclear factor of activated T-cells, cytoplasmic 3 [KO:K17333]
124870122  transcription factor Jun-like [KO:K04448]
124873148  june; junE proto-oncogene, AP-1 transcription factor subunit [KO:K04448]
124873314  jun; transcription factor AP-1 [KO:K04448]
124869702  transcription factor JunD-like [KO:K04449]
124873689  transcription factor JunD-like [KO:K04449]
124871553  atf2; cyclic AMP-dependent transcription factor ATF-2 isoform X1 [KO:K04450]
124880555  tp53; cellular tumor antigen p53 [KO:K04451]
124856910  ddit3; DNA damage-inducible transcript 3 protein [KO:K04452]
124855516  protein max-like isoform X1 [KO:K04453]
124882029  max; protein max isoform X1 [KO:K04453]
124877644  mef2cb; myocyte enhancer factor 2cb isoform X1 [KO:K04454]
124872611  mef2ca; myocyte enhancer factor 2ca isoform X1 [KO:K04454]
124872781  heat shock protein beta-1-like [KO:K04455]
124875937  hspb1; heat shock protein beta-1 [KO:K04455]
124883780  akt2; RAC-beta serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
124858601  RAC-gamma serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
124867765  akt3b; RAC-gamma serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
124855241  akt1; RAC-alpha serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
124883698  ppm1na; protein phosphatase, Mg2+/Mn2+ dependent, 1Na (putative) [KO:K04457] [EC:3.1.3.16]
124855317  ppm1aa; protein phosphatase 1A [KO:K04457] [EC:3.1.3.16]
124875928  ppm1nb; protein phosphatase, Mg2+/Mn2+ dependent, 1Nb (putative) [KO:K04457] [EC:3.1.3.16]
124883084  ptprr; receptor-type tyrosine-protein phosphatase R [KO:K04458] [EC:3.1.3.48]
124857975  ptpn5; tyrosine-protein phosphatase non-receptor type 5 [KO:K18018] [EC:3.1.3.48]
124875334  tyrosine-protein phosphatase non-receptor type 7-like isoform X1 [KO:K18019] [EC:3.1.3.48]
124859767  dusp1; dual specificity protein phosphatase 1 [KO:K21278] [EC:3.1.3.16 3.1.3.48]
124862854  probable dual specificity protein phosphatase DDB_G0281963 [KO:K04459] [EC:3.1.3.16 3.1.3.48]
124883141  dusp16; dual specificity protein phosphatase 16 [KO:K04459] [EC:3.1.3.16 3.1.3.48]
124855917  dusp8a; dual specificity protein phosphatase 8 isoform X1 [KO:K04459] [EC:3.1.3.16 3.1.3.48]
124876785  dual specificity protein phosphatase 7-like [KO:K04459] [EC:3.1.3.16 3.1.3.48]
124857024  dusp7; dual specificity protein phosphatase 7 [KO:K04459] [EC:3.1.3.16 3.1.3.48]
124864549  probable dual specificity protein phosphatase DDB_G0281963 [KO:K04459] [EC:3.1.3.16 3.1.3.48]
124878024  dusp2; dual specificity protein phosphatase 2 [KO:K04459] [EC:3.1.3.16 3.1.3.48]
124872442  dusp4; dual specificity protein phosphatase 4 [KO:K04459] [EC:3.1.3.16 3.1.3.48]
124867694  dusp5; dual specificity protein phosphatase 5 [KO:K04459] [EC:3.1.3.16 3.1.3.48]
124860055  dusp6; dual specificity protein phosphatase 6 [KO:K21946] [EC:3.1.3.16 3.1.3.48]
124882247  dusp10; dual specificity protein phosphatase 10 [KO:K20216] [EC:3.1.3.16 3.1.3.48]
124862846  dual specificity protein phosphatase 3-like [KO:K17614] [EC:3.1.3.16 3.1.3.48]
124864206  dual specificity protein phosphatase 3-like [KO:K17614] [EC:3.1.3.16 3.1.3.48]
124875424  dusp3a; dual specificity protein phosphatase 3 [KO:K17614] [EC:3.1.3.16 3.1.3.48]
124883597  ppp5c; serine/threonine-protein phosphatase 5 isoform X1 [KO:K04460] [EC:3.1.3.16]
124859043  ppm1ba; protein phosphatase 1B isoform X1 [KO:K04461] [EC:3.1.3.16]
124875125  ppm1bb; protein phosphatase 1bb isoform X1 [KO:K04461] [EC:3.1.3.16]
124862837  heat shock 70 kDa protein 1-like [KO:K03283]
124876141  hspa8; LOW QUALITY PROTEIN: heat shock cognate 71 kDa protein [KO:K03283]
124863906  heat shock 70 kDa protein 1 [KO:K03283]
124884258  hspa8b; heat shock protein family A (Hsp70) member 8b [KO:K03283]
124864112  heat shock 70 kDa protein 1 [KO:K03283]
124864317  heat shock 70 kDa protein 1-like [KO:K03283]
124864443  heat shock 70 kDa protein 1-like [KO:K03283]
124864584  hsc70; heat shock cognate 71 kDa protein [KO:K03283]
124864516  hspa1b; LOW QUALITY PROTEIN: heat shock 70 kDa protein-like [KO:K03283]
124862415  heat shock 70 kDa protein 1 [KO:K03283]
124862599  heat shock 70 kDa protein 1 [KO:K03283]
124883767  mecom; histone-lysine N-methyltransferase MECOM isoform X1 [KO:K04462] [EC:2.1.1.367]
124866462  map2k5; dual specificity mitogen-activated protein kinase kinase 5 [KO:K04463] [EC:2.7.12.2]
124874783  mapk7; mitogen-activated protein kinase 7 isoform X1 [KO:K04464] [EC:2.7.11.24]
124856205  probable nuclear hormone receptor HR38 [KO:K04465]
124871988  nr4a1; nuclear receptor subfamily 4 group A member 1 [KO:K04465]
124863966  mitogen-activated protein kinase kinase kinase 14-like [KO:K04466] [EC:2.7.11.25]
124874891  mitogen-activated protein kinase kinase kinase 14 isoform X1 [KO:K04466] [EC:2.7.11.25]
124862201  mitogen-activated protein kinase kinase kinase 14-like [KO:K04466] [EC:2.7.11.25]
124858595  inhibitor of nuclear factor kappa-B kinase subunit alpha-like [KO:K04467] [EC:2.7.11.10]
124875252  inhibitor of nuclear factor kappa-B kinase subunit alpha-like [KO:K04467] [EC:2.7.11.10]
124877211  ikbkb; inhibitor of nuclear factor kappa-B kinase subunit beta [KO:K07209] [EC:2.7.11.10]
124876519  ikbkg; NF-kappa-B essential modulator isoform X1 [KO:K07210]
124862839  serine/threonine-protein kinase NLK2-like [KO:K04468] [EC:2.7.11.24]
124864339  serine/threonine-protein kinase NLK2-like [KO:K04468] [EC:2.7.11.24]
124860291  nfkb1; nuclear factor NF-kappa-B p105 subunit isoform X1 [KO:K02580]
124858799  nfkb2; nuclear factor NF-kappa-B p100 subunit [KO:K04469]
124880275  rela; transcription factor p65 isoform X1 [KO:K04735]
124883822  relb; transcription factor RelB homolog isoform X1 [KO:K09253]
Compound
C00076  Calcium cation
C00165  Diacylglycerol
C00338  Lipopolysaccharide
C00575  3',5'-Cyclic AMP
C01245  D-myo-Inositol 1,4,5-trisphosphate
Reference
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Chen Z, Gibson TB, Robinson F, Silvestro L, Pearson G, Xu B, Wright A, Vanderbilt C, Cobb MH.
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MAP kinases.
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Chem Rev 101:2449-76 (2001)
DOI:10.1021/cr000241p
Reference
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Tanoue T, Nishida E.
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Docking interactions in the mitogen-activated protein kinase cascades.
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Pharmacol Ther 93:193-202 (2002)
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PMID:12947395
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Dent P, Yacoub A, Fisher PB, Hagan MP, Grant S.
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MAPK pathways in radiation responses.
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Oncogene 22:5885-96 (2003)
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Reference
PMID:12676795
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Huang EJ, Reichardt LF.
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Trk receptors: roles in neuronal signal transduction.
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Annu Rev Biochem 72:609-42 (2003)
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Reference
PMID:11369511
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Harper SJ, LoGrasso P.
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Signalling for survival and death in neurones: the role of stress-activated kinases, JNK and p38.
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Cell Signal 13:299-310 (2001)
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Reference
PMID:12390245
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Takeda K, Ichijo H
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Neuronal p38 MAPK signalling: an emerging regulator of cell fate and function in the nervous system.
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Genes Cells 7:1099-111 (2002)
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Reference
PMID:14597384
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Yang SH, Sharrocks AD, Whitmarsh AJ.
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Transcriptional regulation by the MAP kinase signaling cascades.
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Gene 320:3-21 (2003)
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Reference
PMID:12566928
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Zhu X, Lee HG, Raina AK, Perry G, Smith MA.
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The role of mitogen-activated protein kinase pathways in Alzheimer's disease.
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Neurosignals 11:270-81 (2002)
DOI:10.1159/000067426
Reference
PMID:12849693
  Authors
Cho H, Lee J, Kwak NJ, Lee KH, Rha S, Kim YH, Cho YY, Yang KH, Kim K, Lim Y.
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Silica induces nuclear factor-kappaB activation through TAK1 and NIK in Rat2 cell line.
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Toxicol Lett 143:323-30 (2003)
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Reference
PMID:20602996
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Lemmon MA, Schlessinger J
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Cell signaling by receptor tyrosine kinases.
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Cell 141:1117-34 (2010)
DOI:10.1016/j.cell.2010.06.011
Reference
PMID:22367796
  Authors
Skaper SD
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The neurotrophin family of neurotrophic factors: an overview.
  Journal
Methods Mol Biol 846:1-12 (2012)
DOI:10.1007/978-1-61779-536-7_1
Reference
PMID:23085193
  Authors
Chu WM
  Title
Tumor necrosis factor.
  Journal
Cancer Lett 328:222-5 (2013)
DOI:10.1016/j.canlet.2012.10.014
Reference
PMID:22296764
  Authors
Newton K, Dixit VM
  Title
Signaling in innate immunity and inflammation.
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Cold Spring Harb Perspect Biol 4:a006049 (2012)
DOI:10.1101/cshperspect.a006049
Reference
PMID:19483709
  Authors
Gaestel M, Kotlyarov A, Kracht M
  Title
Targeting innate immunity protein kinase signalling in inflammation.
  Journal
Nat Rev Drug Discov 8:480-99 (2009)
DOI:10.1038/nrd2829
Reference
PMID:23664135
  Authors
Ajibade AA, Wang HY, Wang RF
  Title
Cell type-specific function of TAK1 in innate immune signaling.
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Trends Immunol 34:307-16 (2013)
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PMID:24892271
  Authors
Turner MD, Nedjai B, Hurst T, Pennington DJ
  Title
Cytokines and chemokines: At the crossroads of cell signalling and inflammatory disease.
  Journal
Biochim Biophys Acta 1843:2563-2582 (2014)
DOI:10.1016/j.bbamcr.2014.05.014
Related
pathway
gmu04070  Phosphatidylinositol signaling system
gmu04110  Cell cycle
gmu04115  p53 signaling pathway
gmu04210  Apoptosis
gmu04310  Wnt signaling pathway
KO pathway
ko04010   
LinkDB

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