KEGG   ORTHOLOGY: K04353
Entry
K04353                      KO                                     

Name
RAP1A
Definition
Ras-related protein Rap-1A
Pathway
ko04010  MAPK signaling pathway
ko04014  Ras signaling pathway
ko04015  Rap1 signaling pathway
ko04024  cAMP signaling pathway
ko04062  Chemokine signaling pathway
ko04510  Focal adhesion
ko04530  Tight junction
ko04611  Platelet activation
ko04670  Leukocyte transendothelial migration
ko04720  Long-term potentiation
ko04722  Neurotrophin signaling pathway
ko04934  Cushing syndrome
ko04972  Pancreatic secretion
ko05211  Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K04353  RAP1A; Ras-related protein Rap-1A
   04014 Ras signaling pathway
    K04353  RAP1A; Ras-related protein Rap-1A
   04015 Rap1 signaling pathway
    K04353  RAP1A; Ras-related protein Rap-1A
   04024 cAMP signaling pathway
    K04353  RAP1A; Ras-related protein Rap-1A
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K04353  RAP1A; Ras-related protein Rap-1A
   04530 Tight junction
    K04353  RAP1A; Ras-related protein Rap-1A
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    K04353  RAP1A; Ras-related protein Rap-1A
   04670 Leukocyte transendothelial migration
    K04353  RAP1A; Ras-related protein Rap-1A
   04062 Chemokine signaling pathway
    K04353  RAP1A; Ras-related protein Rap-1A
  09154 Digestive system
   04972 Pancreatic secretion
    K04353  RAP1A; Ras-related protein Rap-1A
  09156 Nervous system
   04720 Long-term potentiation
    K04353  RAP1A; Ras-related protein Rap-1A
   04722 Neurotrophin signaling pathway
    K04353  RAP1A; Ras-related protein Rap-1A
 09160 Human Diseases
  09162 Cancer: specific types
   05211 Renal cell carcinoma
    K04353  RAP1A; Ras-related protein Rap-1A
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    K04353  RAP1A; Ras-related protein Rap-1A
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04031 GTP-binding proteins
    K04353  RAP1A; Ras-related protein Rap-1A
GTP-binding proteins [BR:ko04031]
 Small (monomeric) G-proteins
  Ras Family
   Rap [OT]
    K04353  RAP1A; Ras-related protein Rap-1A
Genes
HSA: 5906(RAP1A)
PTR: 469408(RAP1A)
PPS: 100980934(RAP1A)
GGO: 101125618(RAP1A)
PON: 100433839(RAP1A)
NLE: 100603891(RAP1A)
MCC: 704404(RAP1A)
MCF: 102144586(RAP1A)
CSAB: 103224221(RAP1A)
RRO: 104658932(RAP1A)
RBB: 108525739 108528085(RAP1A)
CJC: 100393183(RAP1A)
SBQ: 101048450(RAP1A)
MMU: 109905(Rap1a)
MCAL: 110290796(Rap1a)
MPAH: 110319932(Rap1a)
RNO: 295347(Rap1a)
MUN: 110549551(Rap1a)
CGE: 100751497(Rap1a)
NGI: 103734905(Rap1a)
HGL: 101698757(Rap1a)
CCAN: 109695156(Rap1a)
OCU: 100351588(RAP1A)
TUP: 102475072(RAP1A)
CFA: 483225(RAP1A)
VVP: 112907935(RAP1A)
AML: 100471801(RAP1A)
UMR: 103675043(RAP1A)
UAH: 113244427(RAP1A)
ORO: 101375466(RAP1A)
ELK: 111143648
FCA: 101094942(RAP1A)
PTG: 102963243(RAP1A)
PPAD: 109272045(RAP1A)
AJU: 106969628(RAP1A)
BTA: 282031(RAP1A)
BOM: 102286224(RAP1A)
BIU: 109555931(RAP1A)
BBUB: 102394947(RAP1A)
CHX: 102176930(RAP1A)
OAS: 101115080(RAP1A)
SSC: 100153199(RAP1A)
CFR: 102516450(RAP1A)
CDK: 105102039(RAP1A)
BACU: 103017880(RAP1A)
LVE: 103069239(RAP1A)
OOR: 101287340(RAP1A)
DLE: 111180034(RAP1A)
PCAD: 102985661(RAP1A)
ECB: 100049912 100058930(RAP1A)
EPZ: 103547802(RAP1A)
EAI: 106828599(RAP1A)
MYB: 102258771(RAP1A)
MYD: 102774675(RAP1A)
MNA: 107545324(RAP1A)
HAI: 109373546(RAP1A)
DRO: 112313714(RAP1A)
PALE: 102879271(RAP1A)
RAY: 107499843(RAP1A)
MJV: 108395546(RAP1A)
LAV: 100676220(RAP1A)
TMU: 101352801
MDO: 100033128(RAP1A)
SHR: 100935403(RAP1A)
PCW: 110218764(RAP1A)
OAA: 100076731(RAP1A)
GGA: 419867(RAP1A)
MGP: 100151696(RAP1A)
CJO: 107324916(RAP1A)
NMEL: 110388047(RAP1A)
APLA: 101800296(RAP1A)
ACYG: 106041314(RAP1A)
TGU: 100151697(RAP1A)
LSR: 110475399(RAP1A)
SCAN: 103823268(RAP1A)
GFR: 102036447(RAP1A)
FAB: 101806584(RAP1A)
PHI: 102112636(RAP1A)
PMAJ: 107214847(RAP1A)
CCAE: 111939824(RAP1A)
CCW: 104692321(RAP1A)
ETL: 114063112(RAP1A)
FPG: 101924077(RAP1A)
FCH: 102052801(RAP1A)
CLV: 102089030(RAP1A)
EGZ: 104126794(RAP1A)
NNI: 104010315(RAP1A)
ACUN: 113488776(RAP1A)
PADL: 103923560(RAP1A)
AAM: 106485263(RAP1A)
ASN: 102385556(RAP1A)
AMJ: 102571106(RAP1A)
PSS: 102461781(RAP1A)
CMY: 102948045(RAP1A)
CPIC: 101952443(RAP1A)
ACS: 100556443(rap1a)
PVT: 110072354(RAP1A)
PBI: 103065471(RAP1A)
PMUR: 107292543(RAP1A)
TSR: 106550518
PMUA: 114599364(RAP1A)
GJA: 107112269(RAP1A)
XLA: 414290(rap1a) 779127(rap1a.L) 780738
XTR: 100124947(rap1a)
NPR: 108789680(RAP1A)
DRE: 406714(rap1ab) 415242(rap1aa)
IPU: 108255244(rap1b) 108265690(rap1a)
PHYP: 113526347(rap1a) 113538035
AMEX: 103022868 103047011(rap1a)
EEE: 113572077(rap1a) 113586523
NCC: 104961557
CSEM: 103385603 103386699(rap1a)
SASA: 106566052(RAP1A) 106567206(RAP1B) 106572472(RAP1B) 106582744(RAP1B)
ELS: 105022336(rap1b) 105023688(rap1a)
SFM: 108928254(rap1a) 108930477
PKI: 111839862 111851087(rap1a)
LCM: 102354992(RAP1A)
CMK: 103182425(rap1a)
RTP: 109939006(rap1b)
CIN: 445785(rap1b)
APLC: 110982135
DME: Dmel_CG1956(Rap1)
DER: 6546030
DSE: 6610415
DSI: Dsimw501_GD13432(Dsim_R)
DAN: 6507581
DSR: 110177618
DPE: 6595862
DMN: 108152172
DWI: 6645841
DAZ: 108612588
DNV: 115564307
DHE: 111596946
DVI: 6622391
MDE: 101892158
AAG: 5571900
AME: 413246
BIM: 100747441
BTER: 100642405
CCAL: 108628416
OBB: 114877648
SOC: 105197651
MPHA: 105834702
AEC: 105152361
ACEP: 105626421
PBAR: 105431454
VEM: 105562403
HST: 105187881
DQU: 106748251
CFO: 105257324
LHU: 105667796
PGC: 109860604
OBO: 105286800
PCF: 106786548
NVI: 100117170
CSOL: 105362693
MDL: 103568558
TCA: 658243
DPA: 109533808
ATD: 109602368
NVL: 108560620
BMOR: 692519(Ras3)
BMAN: 114253491
PMAC: 106712843
PRAP: 111000490
HAW: 110375343
TNL: 113497012
PXY: 105387719
API: 100166893
DNX: 107165088
AGS: 114120531
RMD: 113556321
BTAB: 109038859
CLEC: 106666901
ZNE: 110835691
TUT: 107362689
DPTE: 113795806
PTEP: 107449408
CEL: CELE_C27B7.8(rap-1)
BMY: Bm1_39445
PCAN: 112572369
OBI: 106872353
SHX: MS3_03938
PDAM: 113665889
SPIS: 111340737
DGT: 114521782
TASA: A1Q1_04105
DDI: DDB_G0272857(rapB)
DPP: DICPUDRAFT_26434(rapB)
DFA: DFA_02753
EHI: EHI_004860(203.t00010) EHI_049030 EHI_058090(179.t00009) EHI_101260(5.t00090)
 » show all
Reference
PMID:2642744
  Authors
Kitayama H, Sugimoto Y, Matsuzaki T, Ikawa Y, Noda M
  Title
A ras-related gene with transformation suppressor activity.
  Journal
Cell 56:77-84 (1989)
DOI:10.1016/0092-8674(89)90985-9
  Sequence
[hsa:5906]
LinkDB

KEGG   ORTHOLOGY: K07836
Entry
K07836                      KO                                     

Name
RAP1B
Definition
Ras-related protein Rap-1B
Pathway
ko04010  MAPK signaling pathway
ko04014  Ras signaling pathway
ko04015  Rap1 signaling pathway
ko04024  cAMP signaling pathway
ko04062  Chemokine signaling pathway
ko04510  Focal adhesion
ko04611  Platelet activation
ko04670  Leukocyte transendothelial migration
ko04720  Long-term potentiation
ko04722  Neurotrophin signaling pathway
ko04934  Cushing syndrome
ko04972  Pancreatic secretion
ko05211  Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K07836  RAP1B; Ras-related protein Rap-1B
   04014 Ras signaling pathway
    K07836  RAP1B; Ras-related protein Rap-1B
   04015 Rap1 signaling pathway
    K07836  RAP1B; Ras-related protein Rap-1B
   04024 cAMP signaling pathway
    K07836  RAP1B; Ras-related protein Rap-1B
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K07836  RAP1B; Ras-related protein Rap-1B
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    K07836  RAP1B; Ras-related protein Rap-1B
   04670 Leukocyte transendothelial migration
    K07836  RAP1B; Ras-related protein Rap-1B
   04062 Chemokine signaling pathway
    K07836  RAP1B; Ras-related protein Rap-1B
  09154 Digestive system
   04972 Pancreatic secretion
    K07836  RAP1B; Ras-related protein Rap-1B
  09156 Nervous system
   04720 Long-term potentiation
    K07836  RAP1B; Ras-related protein Rap-1B
   04722 Neurotrophin signaling pathway
    K07836  RAP1B; Ras-related protein Rap-1B
 09160 Human Diseases
  09162 Cancer: specific types
   05211 Renal cell carcinoma
    K07836  RAP1B; Ras-related protein Rap-1B
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    K07836  RAP1B; Ras-related protein Rap-1B
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K07836  RAP1B; Ras-related protein Rap-1B
   04031 GTP-binding proteins
    K07836  RAP1B; Ras-related protein Rap-1B
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   K07836  RAP1B; Ras-related protein Rap-1B
  Exosomal proteins of other body fluids (saliva and urine)
   K07836  RAP1B; Ras-related protein Rap-1B
  Exosomal proteins of colorectal cancer cells
   K07836  RAP1B; Ras-related protein Rap-1B
GTP-binding proteins [BR:ko04031]
 Small (monomeric) G-proteins
  Ras Family
   Rap [OT]
    K07836  RAP1B; Ras-related protein Rap-1B
Genes
HSA: 5908(RAP1B)
PTR: 452065(RAP1B)
PPS: 100995578(RAP1B)
GGO: 101125880(RAP1B)
PON: 100171907(RAP1B)
NLE: 100593411(RAP1B)
MCC: 693750 718171(RAP1B)
MCF: 102133022(RAP1B)
CSAB: 103215555 103238680(RAP1B)
RRO: 104658672(RAP1B)
RBB: 108532250(RAP1B)
CJC: 100411763 100413220(RAP1B)
SBQ: 101036065(RAP1B)
MMU: 215449(Rap1b)
MCAL: 110303320(Rap1b)
MPAH: 110326460(Rap1b)
RNO: 171337(Rap1b)
MUN: 110562243(Rap1b)
CGE: 100769542(Rap1b)
NGI: 103745076(Rap1b)
HGL: 101714409 101726671(Rap1b)
CCAN: 109699305
OCU: 100339891(RAP1B)
TUP: 102472381(RAP1B)
CFA: 608981(RAP1B)
VVP: 112922290(RAP1B)
AML: 100480240(RAP1B)
UMR: 103656863(RAP1B) 103659828
UAH: 113256300(RAP1B)
ORO: 101383971(RAP1B)
ELK: 111141969
FCA: 101095993(RAP1B)
PTG: 102965011(RAP1B)
PPAD: 109259557 109270479(RAP1B)
AJU: 106966345(RAP1B)
BTA: 327708(RAP1B) 789148
BIU: 109559248(RAP1B)
BBUB: 102400135(RAP1B)
CHX: 102174543(RAP1B)
OAS: 101106317(RAP1B) 114113232
SSC: 100152555(RAP1B)
CFR: 102524037(RAP1B)
CDK: 105101089(RAP1B)
BACU: 103018737 103019004(RAP1B)
LVE: 103083426(RAP1B) 103088976
OOR: 101284281(RAP1B)
DLE: 111173766(RAP1B)
PCAD: 102980344(RAP1B)
ECB: 100052025(RAP1B)
EPZ: 103558687(RAP1B)
EAI: 106843586(RAP1B)
MYB: 102254910(RAP1B)
MYD: 102772411(RAP1B)
MNA: 107526932(RAP1B)
HAI: 109381707(RAP1B)
DRO: 112318977(RAP1B)
PALE: 102883778(RAP1B)
RAY: 107512678(RAP1B)
MJV: 108407356
LAV: 100665185(RAP1B)
TMU: 101348129
MDO: 100014092(RAP1B)
SHR: 100920135(RAP1B)
PCW: 110211041(RAP1B)
OAA: 100079331(RAP1B)
GGA: 417840(RAP1B)
MGP: 100543810(RAP1B)
CJO: 107310547(RAP1B)
NMEL: 110392786(RAP1B)
APLA: 101789925(RAP1B)
ACYG: 106046993(RAP1B)
TGU: 100223739(RAP1B)
LSR: 110477997(RAP1B)
SCAN: 103813454(RAP1B)
GFR: 102042554(RAP1B)
FAB: 101812484(RAP1B)
PHI: 102099438(RAP1B)
PMAJ: 107204636(RAP1B)
CCAE: 111932715(RAP1B)
CCW: 104698372(RAP1B)
ETL: 114062143(RAP1B)
FPG: 101924298(RAP1B)
FCH: 102047995(RAP1B)
CLV: 102083646(RAP1B)
EGZ: 104132908(RAP1B)
NNI: 104011007(RAP1B)
ACUN: 113487398(RAP1B)
PADL: 103919959(RAP1B)
AAM: 106488632(RAP1B)
ASN: 102382819(RAP1B)
AMJ: 102561548(RAP1B)
PSS: 102444055(RAP1B)
CMY: 102947916(RAP1B)
CPIC: 101935007(RAP1B)
ACS: 100553457(rap1b)
PVT: 110075099(RAP1B)
PBI: 103064511(RAP1B)
PMUR: 107284411(RAP1B)
TSR: 106545246(RAP1B)
PMUA: 114605252(RAP1B)
GJA: 107105721(RAP1B)
XLA: 108713157 379883(rap1b.L)
XTR: 493557(rap1b)
NPR: 108804561(RAP1B)
DRE: 321107(rap1b)
SRX: 107725524 107732995(rap1b)
SGH: 107553881(rap1b)
CCAR: 109067672 109072174(rap1b)
IPU: 100528315(rap1b)
PHYP: 113532015(rap1b)
AMEX: 103035254(rap1b)
EEE: 113572528(rap1b)
TRU: 101070080
LCO: 104935802(rap1b)
MZE: 101471329
ONL: 100707998(rap1b)
OLA: 101172864
XMA: 102223832
XCO: 114161580
PRET: 103459326(rap1b)
CVG: 107089072(rap1b)
NFU: 107387503(rap1b)
AOCE: 111586839
CSEM: 103382506
LCF: 108901386(rap1b)
SDU: 111225046(rap1b)
SLAL: 111661323
HCQ: 109532657(rap1b)
BPEC: 110161898(rap1b)
MALB: 109974612
SASA: 106576640 106593497(RAP1B)
ELS: 105017798(rap1b)
SFM: 108920959 108936546(rap1b)
PKI: 111844324 111851234(rap1b)
LCM: 102354357(RAP1B)
CMK: 103186117(rap1b)
RTP: 109924294
CIN: 100182890
SKO: 102804872
PTEP: 107455620
TSP: Tsp_02666
MYI: 110443111
SHX: MS3_01653
AQU: 105313915
SCE: YGR152C(RSR1)
ERC: Ecym_1407
KMX: KLMA_60196(RSR1)
NCS: NCAS_0A01890(NCAS0A01890)
NDI: NDAI_0D03820(NDAI0D03820)
TPF: TPHA_0K01820(TPHA0K01820)
TBL: TBLA_0B00370(TBLA0B00370)
TDL: TDEL_0F02770(TDEL0F02770)
KAF: KAFR_0F03670(KAFR0F03670)
CAL: CAALFM_CR02140WA(RSR1)
CDU: CD36_27060(RSR1)
SLB: AWJ20_3825(RSR1)
SMP: SMAC_09077(putative krev1)
MGR: MGG_02727
TRE: TRIREDRAFT_76880(rsr1)
MAW: MAC_00973
MAJ: MAA_10959
CMT: CCM_00788
BFU: BCIN_08g02920(Bcrsr1)
MBE: MBM_09336
ANG: ANI_1_524064(An07g04240)
ABE: ARB_00736
TVE: TRV_08011
PTE: PTT_20340
DDI: DDB_G0291237(rapA)
DPP: DICPUDRAFT_59134(rapA)
DFA: DFA_03257 DFA_12095(rapA)
 » show all
Reference
  Authors
Zwartkruis FJ, Bos JL
  Title
Ras and Rap1: two highly related small GTPases with distinct function.
  Journal
Exp Cell Res 253:157-65 (1999)
DOI:10.1006/excr.1999.4695
Reference
PMID:3137530
  Authors
Pizon V, Lerosey I, Chardin P, Tavitian A
  Title
Nucleotide sequence of a human cDNA encoding a ras-related protein (rap1B).
  Journal
Nucleic Acids Res 16:7719 (1988)
DOI:10.1093/nar/16.15.7719
  Sequence
[hsa:5908]
LinkDB

DBGET integrated database retrieval system