KEGG   PATHWAY: sspl03015
Entry
sspl03015                   Pathway                                
Name
mRNA surveillance pathway - Salvia splendens (scarlet sage)
Description
The mRNA surveillance pathway is a quality control mechanism that detects and degrades abnormal mRNAs. These pathways include nonsense-mediated mRNA decay (NMD), nonstop mRNA decay (NSD), and no-go decay (NGD). NMD is a mechanism that eliminates mRNAs containing premature translation-termination codons (PTCs). In vertebrates, PTCs trigger efficient NMD when located upstream of an exon junction complex (EJC). Upf3, together with Upf1 and Upf2, may signal the presence of the PTC to the 5'end of the transcript, resulting in decapping and rapid exonucleolytic digestion of the mRNA. In the NSD pathway, which targets mRNAs lacking termination codons, the ribosome is believed to translate through the 3' untranslated region and stall at the end of the poly(A) tail. NSD involves an eRF3-like protein, Ski7p, which is hypothesized to bind the empty A site of the ribosome and recruit the exosome to degrade the mRNA from the 3' end. NGD targets mRNAs with stalls in translation elongation for endonucleolytic cleavage in a process involving the Dom34 and Hbs1 proteins.
Class
Genetic Information Processing; Translation
Pathway map
sspl03015  mRNA surveillance pathway
sspl03015

Other DBs
GO: 0071028
Organism
Salvia splendens (scarlet sage) [GN:sspl]
Gene
121759271  nuclear cap-binding protein subunit 1-like [KO:K12882]
121755245  nuclear cap-binding protein subunit 1-like [KO:K12882]
121759094  nuclear cap-binding protein subunit 2-like [KO:K12883]
121793171  nuclear cap-binding protein subunit 2-like [KO:K12883]
121780470  nuclear cap-binding protein subunit 2-like [KO:K12883]
121783082  nuclear cap-binding protein subunit 2-like [KO:K12883]
121758872  regulator of nonsense transcripts UPF3-like isoform X1 [KO:K14328]
121805826  regulator of nonsense transcripts UPF3-like isoform X1 [KO:K14328]
121808386  regulator of nonsense transcripts UPF3-like isoform X1 [KO:K14328]
121755296  regulator of nonsense transcripts UPF3-like isoform X1 [KO:K14328]
121755355  regulator of nonsense transcripts UPF3-like [KO:K14328]
121748351  RNA-binding protein Y14A-like [KO:K12876]
121762345  RNA-binding protein Y14A-like [KO:K12876]
121751844  RNA-binding protein Y14A-like [KO:K12876]
121796975  RNA-binding protein Y14A-like [KO:K12876]
121741148  protein mago nashi homolog [KO:K12877]
121742933  protein mago nashi homolog [KO:K12877]
121756854  eukaryotic initiation factor 4A-3-like [KO:K13025] [EC:5.6.2.7]
121779636  eukaryotic initiation factor 4A-3-like [KO:K13025] [EC:5.6.2.7]
121766593  eukaryotic initiation factor 4A-3-like [KO:K13025] [EC:5.6.2.7]
121753724  eukaryotic initiation factor 4A-3-like [KO:K13025] [EC:5.6.2.7]
121782557  eukaryotic initiation factor 4A-3 [KO:K13025] [EC:5.6.2.7]
121788644  histone deacetylase complex subunit SAP18-like [KO:K14324]
121792760  histone deacetylase complex subunit SAP18-like [KO:K14324]
121753669  histone deacetylase complex subunit SAP18-like [KO:K14324]
121759296  pinin-like [KO:K13114]
121804752  pinin-like [KO:K13114]
121808461  pinin-like [KO:K13114]
121755846  pinin-like [KO:K13114]
121785058  actin cytoskeleton-regulatory complex protein PAN1-like [KO:K12875]
121787410  histone-lysine N-methyltransferase SETD1B-like [KO:K12875]
121756564  serine/arginine-rich splicing factor SR45-like isoform X1 [KO:K14325]
121744923  serine/arginine-rich splicing factor SR45-like [KO:K14325]
121758787  serine/arginine-rich splicing factor SR45-like isoform X1 [KO:K14325]
121741698  serine/arginine-rich splicing factor SR45-like [KO:K14325]
121744720  THO complex subunit 4A-like [KO:K12881]
121760838  THO complex subunit 4A-like [KO:K12881]
121788841  THO complex subunit 4D-like [KO:K12881]
121775437  THO complex subunit 4D-like [KO:K12881]
121777742  THO complex subunit 4D-like [KO:K12881]
121741987  THO complex subunit 4A-like [KO:K12881]
121742175  THO complex subunit 4A-like [KO:K12881]
121768472  THO complex subunit 4D-like isoform X1 [KO:K12881]
121799034  DEAD-box ATP-dependent RNA helicase 38-like [KO:K18655] [EC:5.6.2.7]
121765043  DEAD-box ATP-dependent RNA helicase 38-like [KO:K18655] [EC:5.6.2.7]
121797254  DEAD-box ATP-dependent RNA helicase 38-like [KO:K18655] [EC:5.6.2.7]
121797256  DEAD-box ATP-dependent RNA helicase 38-like [KO:K18655] [EC:5.6.2.7]
121805553  protein GLE1-like isoform X1 [KO:K18723]
121807471  protein GLE1-like isoform X1 [KO:K18723]
121785448  DEAD-box ATP-dependent RNA helicase 15-like [KO:K12812] [EC:5.6.2.7]
121748168  DEAD-box ATP-dependent RNA helicase 15-like [KO:K12812] [EC:5.6.2.7]
121791213  DEAD-box ATP-dependent RNA helicase 15-like [KO:K12812] [EC:5.6.2.7]
121804458  DEAD-box ATP-dependent RNA helicase 15-like [KO:K12812] [EC:5.6.2.7]
121779931  DEAD-box ATP-dependent RNA helicase 15 [KO:K12812] [EC:5.6.2.7]
121752369  DEAD-box ATP-dependent RNA helicase 15-like [KO:K12812] [EC:5.6.2.7]
121782562  DEAD-box ATP-dependent RNA helicase 15 [KO:K12812] [EC:5.6.2.7]
121809583  DEAD-box ATP-dependent RNA helicase 15-like [KO:K12812] [EC:5.6.2.7]
121744762  partner of Y14 and mago-like [KO:K14294]
121741236  partner of Y14 and mago-like [KO:K14294]
121749590  serine/arginine repetitive matrix protein 1-like isoform X1 [KO:K13171]
121752304  serine/arginine repetitive matrix protein 1-like [KO:K13171]
121785309  mRNA cap guanine-N7 methyltransferase 1-like [KO:K00565] [EC:2.1.1.56]
121785921  mRNA cap guanine-N7 methyltransferase 1-like [KO:K00565] [EC:2.1.1.56]
121778661  mRNA cap guanine-N7 methyltransferase 2-like [KO:K00565] [EC:2.1.1.56]
121780976  mRNA cap guanine-N7 methyltransferase 2-like isoform X1 [KO:K00565] [EC:2.1.1.56]
121787423  transcription initiation factor TFIID subunit 15b [KO:K13098]
121748595  transcription initiation factor TFIID subunit 15b-like [KO:K13098]
121784989  polyadenylate-binding protein 2-like isoform X1 [KO:K14396]
121811456  polyadenylate-binding protein 1-like [KO:K14396]
121744593  polyadenylate-binding protein 1 [KO:K14396]
121800200  polyadenylate-binding protein 1-like [KO:K14396]
121787488  polyadenylate-binding protein 2-like [KO:K14396]
121787505  polyadenylate-binding protein 2-like [KO:K14396]
121763597  polyadenylate-binding protein 2-like isoform X1 [KO:K14396]
121797314  polyadenylate-binding protein 1-like [KO:K14396]
121801356  pre-mRNA cleavage factor Im 25 kDa subunit 2 [KO:K14397]
121804779  pre-mRNA cleavage factor Im 25 kDa subunit 1-like isoform X1 [KO:K14397]
121751052  pre-mRNA cleavage factor Im 25 kDa subunit 1-like isoform X1 [KO:K14397]
121805807  pre-mRNA cleavage factor Im 25 kDa subunit 2-like [KO:K14397]
121794684  pre-mRNA cleavage factor Im 25 kDa subunit 2 [KO:K14397]
121808665  pre-mRNA cleavage factor Im 25 kDa subunit 1-like isoform X1 [KO:K14397]
121809995  pre-mRNA cleavage factor Im 25 kDa subunit 2-like [KO:K14397]
121801836  cleavage and polyadenylation specificity factor subunit 6-like [KO:K14398]
121801837  cleavage and polyadenylation specificity factor subunit 6-like [KO:K14398]
121748569  cleavage and polyadenylation specificity factor subunit 6-like [KO:K14398]
121789472  cleavage and polyadenylation specificity factor subunit 6-like [KO:K14398]
121804021  cleavage and polyadenylation specificity factor subunit 6-like [KO:K14398]
121752239  cleavage and polyadenylation specificity factor subunit 6-like [KO:K14398]
121752321  cleavage and polyadenylation specificity factor subunit 6-like isoform X1 [KO:K14398]
121808497  cleavage and polyadenylation specificity factor subunit 6-like [KO:K14398]
121810021  cleavage and polyadenylation specificity factor subunit 6-like [KO:K14398]
121756471  nuclear poly(A) polymerase 1-like [KO:K14376] [EC:2.7.7.19]
121771274  nuclear poly(A) polymerase 4-like [KO:K14376] [EC:2.7.7.19]
121771812  nuclear poly(A) polymerase 1-like [KO:K14376] [EC:2.7.7.19]
121767489  nuclear poly(A) polymerase 4-like isoform X1 [KO:K14376] [EC:2.7.7.19]
121768337  nuclear poly(A) polymerase 1-like [KO:K14376] [EC:2.7.7.19]
121797805  nuclear poly(A) polymerase 4-like isoform X1 [KO:K14376] [EC:2.7.7.19]
121805268  protein CLP1 homolog [KO:K14399] [EC:2.7.1.78]
121809714  protein CLP1 homolog [KO:K14399] [EC:2.7.1.78]
121786275  uncharacterized protein LOC121786275 isoform X1 [KO:K14400]
121758847  polyadenylation and cleavage factor homolog 4-like [KO:K14400]
121746888  uncharacterized protein LOC121746888 [KO:K14400]
121762592  uncharacterized protein LOC121762592 isoform X1 [KO:K14400]
121805759  polyadenylation and cleavage factor homolog 4-like isoform X1 [KO:K14400]
121765016  uncharacterized protein LOC121765016 [KO:K14400]
121754877  polyadenylation and cleavage factor homolog 4-like [KO:K14400]
121755578  polyadenylation and cleavage factor homolog 4-like [KO:K14400]
121802041  cleavage and polyadenylation specificity factor subunit 1-like isoform X1 [KO:K14401]
121779976  cleavage and polyadenylation specificity factor subunit 1-like isoform X1 [KO:K14401]
121802454  cleavage and polyadenylation specificity factor subunit 2-like [KO:K14402]
121806732  cleavage and polyadenylation specificity factor subunit 2-like [KO:K14402]
121772208  cleavage and polyadenylation specificity factor subunit 3-I-like [KO:K14403] [EC:3.1.27.-]
121769003  cleavage and polyadenylation specificity factor subunit 3-I-like [KO:K14403] [EC:3.1.27.-]
121788587  uncharacterized protein LOC121788587 [KO:K14404]
121804538  30-kDa cleavage and polyadenylation specificity factor 30-like [KO:K14404]
121778293  uncharacterized protein LOC121778293 [KO:K14404]
121781117  GATA zinc finger domain-containing protein 14-like [KO:K14404]
121808140  30-kDa cleavage and polyadenylation specificity factor 30-like [KO:K14404]
121805529  flowering time control protein FY-like isoform X1 [KO:K15542]
121809420  flowering time control protein FY-like [KO:K15542]
121770888  protein ANTHESIS POMOTING FACTOR 1-like isoform X1 [KO:K14962]
121778172  protein ANTHESIS POMOTING FACTOR 1-like [KO:K14962]
121780859  protein ANTHESIS POMOTING FACTOR 1-like [KO:K14962]
121769388  protein ANTHESIS POMOTING FACTOR 1-like [KO:K14962]
121798814  serine/threonine-protein phosphatase PP1 isozyme 9-like isoform X1 [KO:K06269] [EC:3.1.3.16]
121798929  serine/threonine-protein phosphatase PP1 isozyme 9 [KO:K06269] [EC:3.1.3.16]
121745196  serine/threonine-protein phosphatase PP1 isozyme 2-like [KO:K06269] [EC:3.1.3.16]
121746418  serine/threonine-protein phosphatase PP1 isozyme 2-like [KO:K06269] [EC:3.1.3.16]
121787815  serine/threonine-protein phosphatase PP1 isozyme 2 [KO:K06269] [EC:3.1.3.16]
121762115  serine/threonine-protein phosphatase PP1 isozyme 3-like [KO:K06269] [EC:3.1.3.16]
121749124  serine/threonine-protein phosphatase PP1 isozyme 9-like [KO:K06269] [EC:3.1.3.16]
121804598  serine/threonine-protein phosphatase PP1 isozyme 3-like [KO:K06269] [EC:3.1.3.16]
121805219  serine/threonine-protein phosphatase PP1-like [KO:K06269] [EC:3.1.3.16]
121764936  serine/threonine-protein phosphatase PP1 isozyme 9-like [KO:K06269] [EC:3.1.3.16]
121765499  serine/threonine-protein phosphatase PP1 [KO:K06269] [EC:3.1.3.16]
121752495  serine/threonine-protein phosphatase PP1 isozyme 2-like [KO:K06269] [EC:3.1.3.16]
121807558  serine/threonine-protein phosphatase PP1-like [KO:K06269] [EC:3.1.3.16]
121741484  serine/threonine-protein phosphatase PP1 isozyme 2-like [KO:K06269] [EC:3.1.3.16]
121795255  serine/threonine-protein phosphatase PP1 isozyme 9-like [KO:K06269] [EC:3.1.3.16]
121795257  serine/threonine-protein phosphatase PP1 isozyme 9-like [KO:K06269] [EC:3.1.3.16]
121742077  serine/threonine-protein phosphatase PP1 isozyme 2-like [KO:K06269] [EC:3.1.3.16]
121808443  serine/threonine-protein phosphatase PP1 isozyme 3-like [KO:K06269] [EC:3.1.3.16]
121796704  serine/threonine-protein phosphatase PP1 isozyme 9-like [KO:K06269] [EC:3.1.3.16]
121743173  serine/threonine-protein phosphatase PP1 isozyme 2-like [KO:K06269] [EC:3.1.3.16]
121746931  RNA polymerase II subunit A C-terminal domain phosphatase SSU72-like [KO:K15544] [EC:3.1.3.16]
121752089  RNA polymerase II subunit A C-terminal domain phosphatase SSU72-like [KO:K15544] [EC:3.1.3.16]
121786098  cleavage stimulation factor subunit 50-like isoform X1 [KO:K14406]
121748807  cleavage stimulation factor subunit 50-like isoform X1 [KO:K14406]
121772146  cleavage stimulating factor 64-like [KO:K14407]
121777648  cleavage stimulating factor 64-like isoform X1 [KO:K14407]
121768953  cleavage stimulating factor 64-like [KO:K14407]
121788022  cleavage stimulation factor subunit 77-like [KO:K14408]
121742273  cleavage stimulation factor subunit 77-like isoform X1 [KO:K14408]
121758371  uncharacterized protein LOC121758371 isoform X1 [KO:K06100]
121806866  symplekin-like isoform X1 [KO:K06100]
121795614  uncharacterized protein LOC121795614 isoform X1 [KO:K06100]
121754949  uncharacterized protein LOC121754949 [KO:K06100]
121756349  heterogeneous nuclear ribonucleoprotein 1-like [KO:K14411]
121756350  heterogeneous nuclear ribonucleoprotein 1-like [KO:K14411]
121798659  heterogeneous nuclear ribonucleoprotein 1-like [KO:K14411]
121811648  heterogeneous nuclear ribonucleoprotein 1-like [KO:K14411]
121756851  heterogeneous nuclear ribonucleoprotein 1-like [KO:K14411]
121757100  heterogeneous nuclear ribonucleoprotein 1-like [KO:K14411]
121745621  heterogeneous nuclear ribonucleoprotein 1-like [KO:K14411]
121801125  heterogeneous nuclear ribonucleoprotein 1-like [KO:K14411]
121747618  heterogeneous nuclear ribonucleoprotein 1-like isoform X1 [KO:K14411]
121774878  DAZ-associated protein 1-like isoform X1 [KO:K14411]
121775101  RNA-binding protein Musashi homolog 2-like [KO:K14411]
121762318  heterogeneous nuclear ribonucleoprotein 1-like [KO:K14411]
121777132  RNA-binding protein Musashi homolog 2-like [KO:K14411]
121763219  heterogeneous nuclear ribonucleoprotein 1-like [KO:K14411]
121777649  heterogeneous nuclear ribonucleoprotein 1-like [KO:K14411]
121804910  heterogeneous nuclear ribonucleoprotein 1-like [KO:K14411]
121805769  heterogeneous nuclear ribonucleoprotein 1-like [KO:K14411]
121752489  heterogeneous nuclear ribonucleoprotein 1-like [KO:K14411]
121766272  heterogeneous nuclear ribonucleoprotein 1-like [KO:K14411]
121794402  heterogeneous nuclear ribonucleoprotein 1-like isoform X1 [KO:K14411]
121742188  heterogeneous nuclear ribonucleoprotein 1-like [KO:K14411]
121754219  heterogeneous nuclear ribonucleoprotein 1-like [KO:K14411]
121755031  heterogeneous nuclear ribonucleoprotein 1-like [KO:K14411]
121809700  heterogeneous nuclear ribonucleoprotein 1-like [KO:K14411]
121743512  heterogeneous nuclear ribonucleoprotein 1-like [KO:K14411]
121783576  heterogeneous nuclear ribonucleoprotein 1-like [KO:K14411]
121744569  polyadenylate-binding protein 2-like [KO:K13126]
121756458  polyadenylate-binding protein 8-like [KO:K13126]
121756459  polyadenylate-binding protein 2-like [KO:K13126]
121769562  polyadenylate-binding protein 8-like isoform X1 [KO:K13126]
121758681  polyadenylate-binding protein 8-like [KO:K13126]
121785949  polyadenylate-binding protein 7-like [KO:K13126]
121759323  polyadenylate-binding protein 2-like [KO:K13126]
121759366  polyadenylate-binding protein 8-like [KO:K13126]
121747667  polyadenylate-binding protein 7-like isoform X1 [KO:K13126]
121761080  polyadenylate-binding protein 5-like [KO:K13126]
121788552  polyadenylate-binding protein 8-like [KO:K13126]
121763075  30S ribosomal protein 2, chloroplastic-like [KO:K13126]
121763265  30S ribosomal protein 2, chloroplastic-like [KO:K13126]
121763403  polyadenylate-binding protein 7-like [KO:K13126]
121766084  polyadenylate-binding protein 5-like [KO:K13126]
121794250  polyadenylate-binding protein 4-like [KO:K13126]
121741779  polyadenylate-binding protein 2-like [KO:K13126]
121808048  polyadenylate-binding protein 2-like isoform X1 [KO:K13126]
121797743  polyadenylate-binding protein 6-like isoform X1 [KO:K13126]
121809985  uncharacterized protein LOC121809985 isoform X1 [KO:K13126]
121798873  eukaryotic peptide chain release factor subunit 1-3-like [KO:K03265]
121801809  eukaryotic peptide chain release factor subunit 1-3-like [KO:K03265]
121762054  eukaryotic peptide chain release factor subunit 1-3 [KO:K03265]
121749419  eukaryotic peptide chain release factor subunit 1-3-like [KO:K03265]
121792361  eukaryotic peptide chain release factor subunit 1-3-like [KO:K03265]
121806420  eukaryotic peptide chain release factor subunit 1-3-like [KO:K03265]
121795321  eukaryotic peptide chain release factor subunit 1-3-like [KO:K03265]
121782523  eukaryotic peptide chain release factor subunit 1-3-like [KO:K03265]
121799765  eukaryotic peptide chain release factor GTP-binding subunit ERF3A-like isoform X1 [KO:K03267]
121796048  eukaryotic peptide chain release factor GTP-binding subunit ERF3A-like isoform X1 [KO:K03267]
121747967  regulator of nonsense transcripts UPF2-like [KO:K14327]
121751974  regulator of nonsense transcripts UPF2-like [KO:K14327]
121805101  uncharacterized protein LOC121805101 isoform X1 [KO:K08873] [EC:2.7.11.1]
121807786  serine/threonine-protein kinase SMG1-like isoform X1 [KO:K08873] [EC:2.7.11.1]
121747764  protein SMG7-like [KO:K14409]
121747827  protein SMG7-like isoform X1 [KO:K14409]
121751827  protein SMG7-like [KO:K14409]
121752203  protein SMG7-like [KO:K14409]
121743906  serine/threonine-protein phosphatase PP2A-2 catalytic subunit-like [KO:K04382] [EC:3.1.3.16]
121756462  serine/threonine-protein phosphatase PP2A-2 catalytic subunit-like [KO:K04382] [EC:3.1.3.16]
121798156  serine/threonine-protein phosphatase PP2A-2 catalytic subunit [KO:K04382] [EC:3.1.3.16]
121756972  serine/threonine-protein phosphatase PP2A-2 catalytic subunit-like [KO:K04382] [EC:3.1.3.16]
121772339  serine/threonine-protein phosphatase PP2A catalytic subunit [KO:K04382] [EC:3.1.3.16]
121774746  serine/threonine-protein phosphatase PP2A-2 catalytic subunit-like [KO:K04382] [EC:3.1.3.16]
121762073  serine/threonine-protein phosphatase PP2A-2 catalytic subunit-like [KO:K04382] [EC:3.1.3.16]
121777313  serine/threonine-protein phosphatase PP2A-2 catalytic subunit-like [KO:K04382] [EC:3.1.3.16]
121805256  serine/threonine-protein phosphatase PP2A-2 catalytic subunit [KO:K04382] [EC:3.1.3.16]
121765825  serine/threonine-protein phosphatase PP2A-2 catalytic subunit-like [KO:K04382] [EC:3.1.3.16]
121794775  serine/threonine-protein phosphatase PP2A-2 catalytic subunit [KO:K04382] [EC:3.1.3.16]
121741914  serine/threonine-protein phosphatase PP2A-2 catalytic subunit-like [KO:K04382] [EC:3.1.3.16]
121808582  serine/threonine-protein phosphatase PP2A-2 catalytic subunit-like [KO:K04382] [EC:3.1.3.16]
121755475  serine/threonine-protein phosphatase PP2A-2 catalytic subunit-like [KO:K04382] [EC:3.1.3.16]
121769009  serine/threonine-protein phosphatase PP2A-2 catalytic subunit-like [KO:K04382] [EC:3.1.3.16]
121772062  serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform-like isoform X1 [KO:K03456]
121748427  serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform-like [KO:K03456]
121750086  serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform-like [KO:K03456]
121780455  serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform [KO:K03456]
121783054  serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform-like [KO:K03456]
121769362  serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform-like isoform X1 [KO:K03456]
121784987  serine/threonine protein phosphatase 2A 55 kDa regulatory subunit B beta isoform-like isoform X1 [KO:K04354]
121744726  serine/threonine protein phosphatase 2A 55 kDa regulatory subunit B beta isoform-like isoform X1 [KO:K04354]
121772232  serine/threonine protein phosphatase 2A 55 kDa regulatory subunit B beta isoform-like [KO:K04354]
121787584  serine/threonine protein phosphatase 2A 55 kDa regulatory subunit B beta isoform-like [KO:K04354]
121779997  serine/threonine protein phosphatase 2A 55 kDa regulatory subunit B beta isoform-like isoform X1 [KO:K04354]
121794223  serine/threonine protein phosphatase 2A 55 kDa regulatory subunit B beta isoform-like [KO:K04354]
121741736  serine/threonine protein phosphatase 2A 55 kDa regulatory subunit B beta isoform-like isoform X1 [KO:K04354]
121782628  serine/threonine protein phosphatase 2A 55 kDa regulatory subunit B beta isoform-like isoform X1 [KO:K04354]
121768377  serine/threonine protein phosphatase 2A 55 kDa regulatory subunit B beta isoform-like [KO:K04354]
121797790  serine/threonine protein phosphatase 2A 55 kDa regulatory subunit B beta isoform-like [KO:K04354]
121799012  probable serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit TON2 isoform X1 [KO:K11583]
121745405  serine/threonine protein phosphatase 2A regulatory subunit B''beta-like [KO:K11583]
121762144  serine/threonine protein phosphatase 2A regulatory subunit B''beta-like [KO:K11583]
121749252  probable serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit TON2 [KO:K11583]
121749636  serine/threonine protein phosphatase 2A regulatory subunit B''beta-like [KO:K11583]
121792385  serine/threonine protein phosphatase 2A regulatory subunit B''beta-like isoform X1 [KO:K11583]
121765104  probable serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit TON2 [KO:K11583]
121765140  serine/threonine protein phosphatase 2A regulatory subunit B''beta-like [KO:K11583]
121795350  probable serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit TON2 [KO:K11583]
121742095  serine/threonine protein phosphatase 2A regulatory subunit B''beta-like [KO:K11583]
121743894  serine/threonine protein phosphatase 2A 57 kDa regulatory subunit B' kappa isoform-like [KO:K11584]
121784836  serine/threonine protein phosphatase 2A 57 kDa regulatory subunit B' kappa isoform-like [KO:K11584]
121756857  serine/threonine protein phosphatase 2A 59 kDa regulatory subunit B' gamma isoform-like [KO:K11584]
121745541  serine/threonine protein phosphatase 2A 57 kDa regulatory subunit B' kappa isoform-like [KO:K11584]
121746923  serine/threonine protein phosphatase 2A 57 kDa regulatory subunit B' beta isoform-like [KO:K11584]
121746926  serine/threonine protein phosphatase 2A 57 kDa regulatory subunit B' theta isoform-like [KO:K11584]
121788034  serine/threonine protein phosphatase 2A 57 kDa regulatory subunit B' beta isoform-like [KO:K11584]
121801841  serine/threonine protein phosphatase 2A 57 kDa regulatory subunit B' theta isoform-like [KO:K11584]
121747839  serine/threonine protein phosphatase 2A 57 kDa regulatory subunit B' beta isoform-like [KO:K11584]
121748222  serine/threonine protein phosphatase 2A 57 kDa regulatory subunit B' kappa isoform-like [KO:K11584]
121761251  serine/threonine protein phosphatase 2A 57 kDa regulatory subunit B' beta isoform-like [KO:K11584]
121775177  serine/threonine protein phosphatase 2A 57 kDa regulatory subunit B' theta isoform-like [KO:K11584]
121788739  serine/threonine protein phosphatase 2A 57 kDa regulatory subunit B' beta isoform-like [KO:K11584]
121789696  serine/threonine protein phosphatase 2A 57 kDa regulatory subunit B' kappa isoform-like [KO:K11584]
121748836  serine/threonine protein phosphatase 2A 57 kDa regulatory subunit B' beta isoform-like [KO:K11584]
121748841  serine/threonine protein phosphatase 2A 57 kDa regulatory subunit B' beta isoform-like [KO:K11584]
121762607  serine/threonine protein phosphatase 2A 57 kDa regulatory subunit B' beta isoform-like [KO:K11584]
121790928  serine/threonine protein phosphatase 2A 57 kDa regulatory subunit B' theta isoform-like [KO:K11584]
121777464  serine/threonine protein phosphatase 2A 57 kDa regulatory subunit B' theta isoform-like [KO:K11584]
121750896  serine/threonine protein phosphatase 2A 57 kDa regulatory subunit B' theta isoform-like [KO:K11584]
121778287  serine/threonine protein phosphatase 2A 57 kDa regulatory subunit B' theta isoform-like [KO:K11584]
121805483  serine/threonine protein phosphatase 2A 57 kDa regulatory subunit B' theta isoform-like [KO:K11584]
121751925  serine/threonine protein phosphatase 2A 57 kDa regulatory subunit B' kappa isoform-like [KO:K11584]
121764948  serine/threonine protein phosphatase 2A 57 kDa regulatory subunit B' beta isoform-like [KO:K11584]
121765288  serine/threonine protein phosphatase 2A 57 kDa regulatory subunit B' beta isoform-like [KO:K11584]
121779490  serine/threonine protein phosphatase 2A 57 kDa regulatory subunit B' kappa isoform-like [KO:K11584]
121779641  serine/threonine protein phosphatase 2A 57 kDa regulatory subunit B' beta isoform-like [KO:K11584]
121794522  serine/threonine protein phosphatase 2A 57 kDa regulatory subunit B' theta isoform-like [KO:K11584]
121807476  serine/threonine protein phosphatase 2A 57 kDa regulatory subunit B' alpha isoform-like [KO:K11584]
121753071  serine/threonine protein phosphatase 2A 57 kDa regulatory subunit B' beta isoform-like [KO:K11584]
121782162  serine/threonine protein phosphatase 2A 57 kDa regulatory subunit B' kappa isoform-like [KO:K11584]
121782221  serine/threonine protein phosphatase 2A 57 kDa regulatory subunit B' beta isoform-like [KO:K11584]
121782416  serine/threonine protein phosphatase 2A 57 kDa regulatory subunit B' theta isoform-like [KO:K11584]
121809260  serine/threonine protein phosphatase 2A 57 kDa regulatory subunit B' theta isoform-like [KO:K11584]
121809263  serine/threonine protein phosphatase 2A 57 kDa regulatory subunit B' theta isoform-like [KO:K11584]
121742576  serine/threonine protein phosphatase 2A 57 kDa regulatory subunit B' kappa isoform-like [KO:K11584]
121809384  serine/threonine protein phosphatase 2A 57 kDa regulatory subunit B' theta isoform-like [KO:K11584]
121805084  HBS1-like protein isoform X1 [KO:K14416]
121806250  HBS1-like protein isoform X1 [KO:K14416]
121775041  protein PELOTA 1-like [KO:K06965]
Reference
PMID:15040442
  Authors
Maquat LE
  Title
Nonsense-mediated mRNA decay: splicing, translation and mRNP dynamics.
  Journal
Nat Rev Mol Cell Biol 5:89-99 (2004)
DOI:10.1038/nrm1310
Reference
PMID:16723977
  Authors
Amrani N, Sachs MS, Jacobson A
  Title
Early nonsense: mRNA decay solves a translational problem.
  Journal
Nat Rev Mol Cell Biol 7:415-25 (2006)
DOI:10.1038/nrm1942
Reference
PMID:17183357
  Authors
Eulalio A, Behm-Ansmant I, Izaurralde E
  Title
P bodies: at the crossroads of post-transcriptional pathways.
  Journal
Nat Rev Mol Cell Biol 8:9-22 (2007)
DOI:10.1038/nrm2080
Reference
PMID:18158581
  Authors
Mandel CR, Bai Y, Tong L
  Title
Protein factors in pre-mRNA 3'-end processing.
  Journal
Cell Mol Life Sci 65:1099-122 (2008)
DOI:10.1007/s00018-007-7474-3
Reference
PMID:16715045
  Authors
Clement SL, Lykke-Andersen J
  Title
No mercy for messages that mess with the ribosome.
  Journal
Nat Struct Mol Biol 13:299-301 (2006)
DOI:10.1038/nsmb0406-299
Related
pathway
sspl03013  Nucleocytoplasmic transport
sspl03018  RNA degradation
sspl03040  Spliceosome
KO pathway
ko03015   
LinkDB

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