| D00059 |
Levodopa (JP18/USP/INN); Dopar (TN) |
(P) unclassified |
| D00107 |
Tacrolimus (USP/INN); Tacrolimus hydrate (JP18); Prograf (TN); Protopic (TN) |
(CI) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D00118 |
Naproxen (JP18/USP/INN); Naprosyn (TN) |
(P) unclassified |
| D00136 |
Haloperidol (JP18/USP/INN); Haldol (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D00140 |
Erythromycin (JP18/USP/INN); Akne-mycin (TN); Eryc (TN); Erygel (TN); Pce (TN); Staticin (TN); T-stat (TN) |
(P) unclassified |
| D00151 |
Mefenamic acid (JP18/USP/INN); Ponstel (TN) |
(P) Enzyme: CYP2C9 / CYP induction: CYP2C9 |
| D00184 |
Cyclosporine (USP); Ciclosporin (JP18); Gengraf (TN); Neoral (TN); Restasis (TN); Sandimmune (TN) |
(CI) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 / CYP induction: CYP3A4 |
| D00211 |
Rifampin (USP); Rifampicin (JP18/INN); Rifadin (TN); Rimactane (TN) |
(P) CYP induction: CYP3A4 |
| D00218 |
Acetazolamide (JP18/USP/INN); Diamox (TN) |
(P) unclassified |
| D00228 |
Amoxapine (JP18/USP/INN); Asendin (TN) |
(P) unclassified |
| D00241 |
Baclofen (JP18/USP/INN); Kemstro (TN); Lioresal (TN) |
(P) unclassified |
| D00253 |
Carbidopa hydrate and levodopa; Parcopa (TN); Sinemet (TN) |
(P) unclassified |
| D00283 |
Clozapine (JAN/USP/INN); Clozaril (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D00292 |
Dexamethasone (JP18/USP/INN); Decadron (TN); Maxidex (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D00293 |
Diazepam (JP18/USP/INN); Diastat (TN); Valium (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D00294 |
Diazoxide (JAN/USP/INN); Hyperstat (TN); Proglycem (TN) |
(P) unclassified |
| D00298 |
Digoxin (JP18/USP); Lanoxicaps (TN); Lanoxin (TN) |
(P) unclassified |
| D00302 |
Dipyridamole (JP18/USP/INN); Persantine (TN) |
(P) unclassified |
| D00319 |
Felodipine (JP18/USP/INN); Plendil (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D00320 |
Fentanyl (JAN/USP/INN); Duragesic (TN); Subsys (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D00331 |
Furosemide (JP18/USP/INN); Frusemide; Lasix (TN) |
(P) unclassified |
| D00346 |
Isoniazid (JP18/USP/INN); Laniazid (TN) |
(P) unclassified |
| D00350 |
Itraconazole (JP18/USP); Itrizole (TN); Sporanox (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 / CYP induction: CYP3A4 |
| D00382 |
Torsemide (USP); Torasemide (JAN/INN); Demadex (TN); Luprac (TN) |
(P) Enzyme: CYP2C9 / CYP induction: CYP2C9 |
| D00383 |
Trandolapril (JAN/USP/INN); Mavik (TN) |
(P) unclassified |
| D00387 |
Triazolam (JP18/USP/INN); Halcion (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D00405 |
Methyldopa (USP); Methyldopa hydrate (JP18); Aldomet (TN) |
(P) unclassified |
| D00420 |
Mitotane (JAN/USP/INN); Lysodren (TN) |
(P) unclassified |
| D00426 |
Risperidone (JP18/USP/INN); Risperdal (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D00432 |
Nadolol (JP18/USP/INN); Corgard (TN) |
(P) unclassified |
| D00435 |
Nevirapine (JAN/USP/INN); Viramune (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D00437 |
Nifedipine (JP18/USP/INN); Adalat (TN); Afeditab CR (TN); Procardia (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D00443 |
Spironolactone (JP18/USP/INN); Aldactone (TN) |
(P) unclassified |
| D00458 |
Quetiapine fumarate (JP18/USP); Seroquel (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D00479 |
Prochlorperazine maleate (JP18/USP); Compazine (TN) |
(P) unclassified |
| D00480 |
Promethazine hydrochloride (JP18/USP); Phenergan (TN); Promethegan (TN) |
(P) unclassified |
| D00503 |
Perphenazine (JP18/USP/INN); Trilafon (TN) |
(P) unclassified |
| D00506 |
Phenobarbital (JP18/USP/INN); Luminal (TN) |
(P) CYP induction: CYP2C9 |
| D00512 |
Phenytoin (JP18/USP/INN); Dilantin (TN) |
(P) Enzyme: CYP2C9 / CYP induction: CYP2C9 |
| D00515 |
Nitroglycerin (JP18/USP); Glyceryl trinitrate; Minitran (TN); Nitro-bid (TN); Nitro-dur (TN); Nitromist (TN); Transderm-nitro (TN) |
(P) unclassified |
| D00537 |
Topiramate (JAN/USP/INN); Topamax (TN); Trokendi xr (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D00547 |
Sevoflurane (JP18/USAN/INN); Ultane (TN) |
(P) unclassified |
| D00549 |
Propofol (JAN/USP/INN); Diprivan (TN) |
(P) unclassified |
| D00550 |
Midazolam (JAN/USP/INN); Dormicum (TN); Buccolam (TN); Nayzilam (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D00554 |
Ethinyl estradiol (USP); Ethinylestradiol (JP18/INN); Estinyl (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 / CYP induction: CYP3A4 |
| D00563 |
Mirtazapine (JAN/USP/INN); Remeron (TN); Reflex (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D00599 |
Carteolol hydrochloride (JP18/USP); Cartrol (TN); Ocupress (TN) |
(P) unclassified |
| D00606 |
Guanfacine hydrochloride (JAN/USP); Intuniv (TN); Tenex (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D00608 |
Doxazosin mesylate (USP); Doxazosin mesilate (JP18); Cardura (TN) |
(P) unclassified |
| D00609 |
Prazosin hydrochloride (JP18/USP); Minipress (TN) |
(P) unclassified |
| D00615 |
Amlodipine besylate (USP); Amlodipine besilate (JP18); Norvasc (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D00616 |
Diltiazem hydrochloride (JP18/USP); Cardizem (TN); Cartia XT (TN); Dilacor XR (TN); Dilt-CD (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D00617 |
Nicardipine hydrochloride (JP18/USAN); Cardene (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D00619 |
Verapamil hydrochloride (JP18/USP); Calan (TN); Covera-hs (TN); Vasolan (TN); Verelan (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 / CYP induction: CYP3A4 |
| D00629 |
Nitrendipine (JP18/USAN/INN); Baypress (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D00634 |
Bisoprolol fumarate (JP18/USP); Zebeta (TN) |
(P) unclassified |
| D00636 |
Amiodarone hydrochloride (JP18/USP); Ancaron (TN); Cordarone (TN); Nexterone (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D00658 |
Trichlormethiazide (JP18/USP/INN); Naqua (TN) |
(P) unclassified |
| D00678 |
Ondansetron hydrochloride hydrate (JAN/USP); Ondansetron hydrochloride; Ondansetron hydrochloride dihydrate; Zofran (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D00701 |
Phenobarbital sodium (JAN/USP/INN); Luminal sodium (TN) |
(P) CYP induction: CYP2C9 |
| D00713 |
Thiamylal sodium (JP18); Surital (TN) |
(P) unclassified |
| D00714 |
Thiopental sodium (JP18/USP/INN); Pentothal (TN) |
(P) unclassified |
| D00762 |
Metyrosine (USP); Metirosine (JAN/INN); Demser (TN) |
(P) unclassified |
| D00776 |
Tizanidine hydrochloride (JP18/USP); Zanaflex (TN) |
(P) unclassified |
| D00789 |
Chlorpromazine hydrochloride (JP18/USP); Sonazine (TN) |
(P) unclassified |
| D00793 |
Fluphenazine decanoate (JAN/USP); Prolixin decanoate (TN) |
(P) unclassified |
| D00809 |
Amitriptyline hydrochloride (JP18/USP); Elavil (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D00811 |
Clomipramine hydrochloride (JP18/USP); Anafranil (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D00815 |
Imipramine hydrochloride (JP18/USP); Tofranil (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D00820 |
Trazodone hydrochloride (JAN/USP); Desyrel (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D00831 |
Mefloquine hydrochloride (JP18/USP); Lariam (TN) |
(P) unclassified |
| D00836 |
Buprenorphine hydrochloride (JP18/USP); Buprenex (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D00904 |
Diclofenac sodium (JP18/USP); Solaraze (TN); Voltaren (TN) |
(P) Enzyme: CYP2C9 / CYP induction: CYP2C9 |
| D00961 |
Bicalutamide (JP18/USP/INN); Casodex (TN) |
(P) CYP inhibition: CYP3A4 |
| D00964 |
Letrozole (JAN/USP/INN); Femara (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D00969 |
Meloxicam (JAN/USP/INN); Mobic (TN) |
(P) Enzyme: CYP2C9 / CYP induction: CYP2C9 |
| D00975 |
Dexamethasone sodium phosphate (JAN/USP); Dalalone (TN); Maxidex (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D00987 |
Cabergoline (JP18/USP/INN); Cabaser (TN); Dostinex (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D01024 |
Tamsulosin hydrochloride (JP18/USP); Flomax (TN); Harnal (TN) |
(P) unclassified |
| D01061 |
Irinotecan hydrochloride (USP); Irinotecan hydrochloride hydrate (JP18); Irinotecan hydrochloride trihydrate; CPT 11; CPT-11; Campto (TN); Camptosar (TN); Onivyde (TN) |
(P) unclassified |
| D01104 |
Barnidipine hydrochloride (JAN); Hypoca (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D01107 |
Milnacipran hydrochloride (JAN/USAN); Savella (TN); Toledomin (TN) |
(P) unclassified |
| D01115 |
Eplerenone (JP18/USAN/INN); Inspra (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D01145 |
Azelnidipine (JP18/INN); Calblock (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D01164 |
Aripiprazole (JP18/USP/INN); Abilify (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D01176 |
Blonanserin (JAN/INN); AD 5423 |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D01179 |
Duloxetine hydrochloride (JAN/USP); Cymbalta (TN); Yentreve (TN) |
(P) unclassified |
| D01196 |
Acetazolamide sodium (JAN); Diamox (TN) |
(P) unclassified |
| D01213 |
Tolvaptan (JP18/USAN/INN); Samsca (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D01240 |
Deslanoside (JP18/USP/INN); Cedilanid-d (TN) |
(P) unclassified |
| D01253 |
Clobazam (JAN/USAN/INN); Mystan (TN); Onfi (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D01302 |
Hydralazine hydrochloride (JP18/USP); Apresoline (TN) |
(P) unclassified |
| D01321 |
Zotepine (JAN/INN); Setous (TN) |
(P) unclassified |
| D01323 |
Azosemide (JP18/USAN/INN); Diart (TN) |
(P) unclassified |
| D01333 |
Urapidil (JP18/INN); Ebrantil (TN) |
(P) unclassified |
| D01358 |
Mianserin hydrochloride (JAN/USAN); Tetramide (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D01361 |
Erythromycin ethylsuccinate (JP18/USP); E.E.S. (TN); Eryped (TN); Erythrocin W (TN) |
(P) unclassified |
| D01372 |
Zopiclone (JP18/INN); Amoban (TN); Zopiclone (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D01399 |
Fentanyl citrate (JP18/USP); Abstral (TN); Fentora (TN); Lazanda (TN); Oralet (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D01418 |
Tamibarotene (JAN/USAN/INN); Am 80; Amnoid (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D01469 |
Amosulalol hydrochloride (JP18); Lowgan (TN) |
(P) unclassified |
| D01485 |
Propericiazine (JAN); Periciazine; Neuleptil (TN) |
(P) unclassified |
| D01546 |
Dothiepin hydrochloride (USAN); Dosulepin hydrochloride (JAN); Dosulepin (TN) |
(P) unclassified |
| D01549 |
Imidapril hydrochloride (JP18); Tanatril (TN) |
(P) unclassified |
| D01551 |
Beraprost sodium (JP18/USAN); Procylin (TN) |
(P) unclassified |
| D01553 |
Manidipine hydrochloride (JP18); Manidipine dihydrochloride; Calslot (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D01604 |
Efonidipine hydrochloride ethanolate (JAN); Efonidipine hydrochloride ethanol; Efonidipine hydrochloride; NZ 105 ethanolate; Landel (TN) |
(P) unclassified |
| D01674 |
Naftopidil (JP18/INN); Flivas (TN) |
(P) unclassified |
| D01691 |
Nipradilol (JAN/INN); Hypadil (TN) |
(P) unclassified |
| D01709 |
Loxoprofen sodium hydrate (JP18); Lorfenamin (TN); Loxonin (TN) |
(P) unclassified |
| D01741 |
Celiprolol hydrochloride (JAN/USAN); Selectol (TN) |
(P) unclassified |
| D01744 |
Brotizolam (JP18/USAN/INN); Lendormin (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D01877 |
Mefruside (JP18/USAN/INN); Baycaron (TN) |
(P) unclassified |
| D01887 |
Bunazosin hydrochloride (JP18); Detantol (TN) |
(P) unclassified |
| D01898 |
Haloperidol decanoate (JAN/USP); Halomonth (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D01902 |
Fonazine mesylate (USAN); Dimetotiazine mesilate (JAN); Banistyl (TN) |
(P) unclassified |
| D01908 |
Nilvadipine (JP18/USAN/INN); Nivadil (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D01943 |
Canrenoate potassium (USAN); Potassium canrenoate (JP18); Soldactone (TN) |
(P) unclassified |
| D01965 |
Silodosin (JP18/INN); KMD 3213; Rapaflo (TN); Urief (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D01977 |
Gefitinib (JP18/USAN/INN); Iressa (TN) |
(P) unclassified |
| D02002 |
Isoniazid sodium methanesulfonate hydrate (JAN); Isoniazid sodium methanesulfonate monohydrate; Isoniazid sodium methanesulfonate; IHMS; Neoiscotin (TN) |
(P) unclassified |
| D02008 |
Tadalafil (JAN/USP/INN); Adcirca (TN); Cialis (TN); Zalutia (TN) |
(CI,P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D02009 |
Erythromycin lactobionate (JP18/USP); Erythrocin (TN) |
(P) unclassified |
| D02022 |
Prochlorperazine mesilate (JAN); Prochlorperazine dimethanesulfonate; Novamin (TN) |
(P) unclassified |
| D02034 |
Setiptiline maleate (JAN); Tecipul (TN) |
(P) unclassified |
| D02037 |
Perphenazine maleate (JP18); PZC (TN) |
(P) unclassified |
| D02076 |
Brimonidine tartrate (JAN/USAN); Alphagan (TN) |
(P) unclassified |
| D02103 |
Phenytoin sodium (USP); Phenytoin sodium for injection (JP18); Aleviatin (TN); Dilantin (TN) |
(P) Enzyme: CYP2C9 / CYP induction: CYP2C9 |
| D02135 |
Levodopa and benserazide hydrochloride; Madopar (TN) |
(P) unclassified |
| D02163 |
Fluphenazine maleate (JAN); Flumezin (TN) |
(P) unclassified |
| D02184 |
Erythromycin stearate (JP18/USP); Bristamycin (TN) |
(P) unclassified |
| D02229 |
Sildenafil citrate (JAN/USP); Revatio (TN); Viagra (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D02245 |
Trimeprazine tartrate (USP); Alimemazine tartrate (JP18); Alimezine (TN) |
(P) unclassified |
| D02248 |
Levomepromazine maleate (JP18/USAN); Hirnamin (TN) |
(P) unclassified |
| D02342 |
Bisoprolol (JAN/USAN/INN) |
(P) unclassified |
| D02372 |
Perospirone hydrochloride hydrate (JAN); Lullan (TN) |
(P) unclassified |
| D02408 |
Trimipramine maleate (JAN/USP); Surmontil (TN) |
(P) unclassified |
| D02484 |
Artemether and lumefantrine; Coartem (TN) |
(P) unclassified |
| D02540 |
Garenoxacin mesylate (USAN); Garenoxacin mesilate hydrate (JAN) |
(P) unclassified |
| D02587 |
Metildigoxin (JP18); Lanirapid (TN) |
(P) unclassified |
| D02624 |
Eszopiclone (JAN/USP/INN); Estorra (TN); Lunesta (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D02633 |
Lomerizine hydrochloride (JAN); Terranas (TN) |
(P) unclassified |
| D02691 |
Somatropin (USP/INN); Somatropin (genetical recombination) (JAN); Human growth hormone (JAN); Asellacrin (TN); Humatrope (TN); Nutropin (TN); Omnitrope (TN) |
(P) unclassified |
| D02732 |
Pranlukast hydrate (JP18); Onon (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D02802 |
Alemtuzumab (USAN/INN); Alemtuzumab (genetical recombination) (JAN); Campath (TN); Lemtrada (TN) |
(P) unclassified |
| D02968 |
Aprepitant (JAN/USP/INN); Aponvie (TN); Emend (TN); Cinvanti (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 / CYP induction: CYP3A4 CYP2C9 |
| D02994 |
Rituximab (USAN/INN); Rituximab (genetical recombination) (JAN); Rituximab (genetical recombination) [Rituximab biosimilar 1] (JAN); Rituximab (genetical recombination) [Rituximab biosimilar 2] (JAN); Rituximab-abbs; Rituximab-pvvr; Rituximab-arrx; Rituxan (TN); Riabni (TN); Truximab (TN) |
(P) unclassified |
| D02995 |
Asenapine maleate (JAN/USAN); Saphris (TN) |
(P) unclassified |
| D03106 |
Bexarotene (JAN/USAN/INN); Targretin (TN) |
(P) unclassified |
| D03150 |
Bortezomib (JAN/USAN/INN); Velcade (TN) |
(P) unclassified |
| D03218 |
Axitinib (JAN/USAN); Inlyta (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D03260 |
Vardenafil hydrochloride hydrate (JAN); Vardenafil monohydrochloride trihydrate; Levitra (TN); Staxyn (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D03290 |
Promethazine methylenedisalicylate (JAN); Pyrethia (TN) |
(P) unclassified |
| D03658 |
Dasatinib (JAN/INN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D03669 |
Deferasirox (JAN/USAN/INN); Exjade (TN); Jadenu (TN) |
(P) CYP induction: CYP3A4 |
| D03799 |
Dienogest (JAN/USAN/INN); Endometrion (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D03917 |
Drospirenone (JAN/USP/INN); Slynd (TN); Slinda (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D04023 |
Erlotinib hydrochloride (JAN/USAN); Tarceva (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D04024 |
Lapatinib ditosylate (USAN); Lapatinib tosilate hydrate (JAN); Lapatinib ditosylate monohydrate; Tykerb (TN); Tyverb (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D04034 |
Chlorpromazine phenolphthalinate (JAN); Wintermin (TN) |
(P) unclassified |
| D04038 |
Perphenazine fendizoate (JAN); PZC (TN) |
(P) unclassified |
| D04046 |
Salicylamide, acetaminophen, anhydrous caffeine and promethazine methylenedisalicylate; PL (TN) |
(P) unclassified |
| D04463 |
Norgestrel and ethinylestradiol tablets (JP18); Low-ogestrel (TN); Planovar (TN) |
(P) Enzyme: CYP3A4 CYP2C9 / CYP induction: CYP2C9 CYP3A4 |
| D04482 |
Ethinylestradiol and levonorgestrel; Ange (TN); Levora (TN); Lo/ovral (TN); Seasonique (TN); Triphasil-21 (TN); Trivora (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D04483 |
Ethinylestradiol and norethisterone; Norethindrone and ethinyl estradiol; Synphase T28 (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D04484 |
Desogestrel and ethinylestradiol; Marvelon21 (TN); Ortho-cept (TN) |
(P) Enzyme: CYP3A4 CYP2C9 / CYP induction: CYP2C9 CYP3A4 |
| D04641 |
Istradefylline (JAN/USAN/INN); Nourianz (TN); Nouriast (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 / CYP induction: CYP3A4 |
| D04666 |
Lanreotide acetate (JAN/USAN); Somatuline (TN) |
(P) unclassified |
| D04768 |
Lonafarnib (JAN/USAN/INN); Zokinvy (TN) |
(P) unclassified |
| D04820 |
Lurasidone hydrochloride (JAN/USAN); SM 13496; Latuda (TN) |
(CI,P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D04859 |
Maribavir (JAN/USAN/INN); Camvia (TN); Livtencity (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D04965 |
Perphenazine hydrochloride; Perphenazine dihydrochloride; PZC intramuscular injection (TN) |
(P) unclassified |
| D05177 |
Nitisinone (JAN/USAN/INN); Orfadin (TN) |
(P) CYP inhibition: CYP2C9 |
| D05339 |
Paliperidone (JAN/USP/INN); Invega (TN) |
(P) unclassified |
| D05340 |
Paliperidone palmitate (JAN/USAN); Xeplion (TN); Trevicta (TN); Invega sustenna (TN); Invega trinza (TN) |
(P) unclassified |
| D05380 |
Pazopanib hydrochloride (JAN/USAN); Votrient (TN) |
(P) unclassified |
| D05462 |
Oxycodone hydrochloride hydrate (JP18) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D05775 |
Rufinamide (JAN/USP/INN); Banzel (TN) |
(P) unclassified |
| D06068 |
Temsirolimus (JAN/USAN/INN); Torisel (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D06199 |
Trabectedin (JAN/USAN/INN); Yondelis (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D06272 |
Sorafenib tosylate (USAN); Sorafenib tosilate (JAN); Nexavar (TN) |
(P) unclassified |
| D06402 |
Sunitinib malate (JAN/USAN); Sutent (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D06407 |
Vandetanib (JAN/USAN/INN); Caprelsa (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D06413 |
Nilotinib hydrochloride hydrate (JAN); Nilotinib monohydrochloride monohydrate; Tasigna (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D06414 |
Dasatinib (USAN); Dasatinib hydrate (JAN); Sprycel (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D06478 |
Darunavir ethanolate (JAN); Prezista (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 / CYP induction: CYP3A4 |
| D06597 |
Fosaprepitant dimeglumine (USAN); Fosaprepitant meglumine (JAN); Proemend (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 / CYP induction: CYP3A4 CYP2C9 |
| D07132 |
Buprenorphine (JAN/INN); Temgesic (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D07569 |
Candesartan cilexetil and anmlodipine besylate (JP18); Unisia (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D07583 |
Phenytoin and phenobarbital; Aleviatin with phenobarbital (TN) |
(P) Enzyme: CYP2C9 / CYP induction: CYP2C9 |
| D07595 |
Fosphenytoin sodium hydrate (JAN); Fostoin (TN) |
(P) Enzyme: CYP2C9 / CYP induction: CYP2C9 CYP3A4 |
| D08095 |
Ivabradine hydrochloride (JAN/USAN); Ivabrandine hydrochloride; Corlanor (TN); Corlentor (TN); Coralan (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D08488 |
Amlodipine besilate and atorvastatin calcium; Caduet (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D08575 |
Tetrabenazine (JAN/INN); Nitoman (TN); Xenazine (TN) |
(P) unclassified |
| D08768 |
Promethazine hibenzate; Hiberna (TN) |
(P) unclassified |
| D08856 |
Anamorelin hydrochloride (JAN/USAN); Adlumiz (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D08860 |
Apremilast (JAN/USAN); Otezla (TN) |
(P) unclassified |
| D08923 |
Fesoterodine fumarate (JAN/USAN); Toviaz (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D09017 |
Ticagrelor (JAN/USAN/INN); Brilinta (TN) |
(CI,P) unclassified |
| D09033 |
Voclosporin (JAN/USAN/INN); Lupkynis (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D09321 |
Obinutuzumab (USAN/INN); Obinutuzumab (genetical recombination) (JAN); Gazyva (TN) |
(P) unclassified |
| D09348 |
Fostamatinib disodium (USAN); Fostamatinib sodium hydrate (JAN); Fostamatinib disodium hexahydrate; Tavalisse (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D09572 |
Riociguat (JAN/USAN/INN); Adempas (TN) |
(P) unclassified |
| D09594 |
Olmesartan medoxomil and azelnidipine; Rezaltas (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D09638 |
Lomitapide mesylate (USAN); Lomitapide mesilate (JAN); Juxtapid (TN); Lojuxta (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D09701 |
Abiraterone acetate (JAN/USP); Zytiga (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D09728 |
Bosutinib hydrate (JAN); Bosutinib monohydrate; Bosulif (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D09730 |
Olaparib (JAN/USAN/INN); Lynparza (TN) |
(P) unclassified |
| D09731 |
Crizotinib (JAN/USAN/INN); Xalkori (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D09741 |
Drospirenone and ethinylestradiol; Drospirenone and ethinylestradiol betadex; Angeliq (TN); Yaz (TN); Flexyess (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D09743 |
Telmisartan and amlodipine besilate (JP18); Telmisartan and amlodipine besylate; Micamlo (TN); Twynsta (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D09745 |
Valsartan and amlodipine besilate; Exforge (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D09783 |
Tofacitinib citrate (JAN/USAN); Tasocitinib citrate; Xeljanz (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D09799 |
Carotegrast methyl (JAN); Carogra (TN) |
(P) CYP inhibition: CYP3A4 |
| D09873 |
Bedaquiline fumarate (JAN/USAN); Sirturo (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D09894 |
Eliglustat tartrate (JAN/USAN); Eliglustat hemitartrate; Cerdelga (TN) |
(P) unclassified |
| D09920 |
Lenvatinib mesylate (USAN); Lenvatinib mesilate (JAN); Lenvima (TN) |
(P) unclassified |
| D09951 |
Ponatinib hydrochloride (JAN/USAN); Iclusig (TN) |
(P) unclassified |
| D09956 |
Quizartinib dihydrochloride (USAN); Quizartinib hydrochloride (JAN); Vanflyta (TN) |
(P) unclassified |
| D09960 |
Ruxolitinib phosphate (JAN/USAN); Jakafi (TN); Jakavi (TN); Opzelura (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D09996 |
Vemurafenib (JAN/USAN/INN); Zelboraf (TN) |
(P) CYP inhibition: CYP2C9 / CYP induction: CYP3A4 |
| D10003 |
Hemin (JAN); Normosang (TN); Panhematin (TN) |
(P) CYP induction: CYP3A4 |
| D10024 |
Selumetinib sulfate (JAN/USAN); Koselugo (TN) |
(P) Enzyme: CYP2C9 CYP3A4 / CYP induction: CYP2C9 CYP3A4 |
| D10082 |
Suvorexant (JAN/USAN); MK-4305; Belsomra (TN) |
(P) unclassified |
| D10095 |
Cabozantinib s-malate (USAN); Cabozantinib malate (JAN); Cometriq (TN); Cabometyx (TN) |
(P) unclassified |
| D10104 |
Dabrafenib mesylate (USAN); Dabrafenib mesilate (JAN); Tafinlar (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 CYP2C9 |
| D10131 |
Ixazomib citrate (JAN/USAN); Ninlaro (TN) |
(P) unclassified |
| D10135 |
Macitentan (JAN/USAN); Opsumit (TN) |
(CI,P) Enzyme: CYP3A4 / Target: EDNRA EDNRB / CYP induction: CYP3A4 |
| D10137 |
Regorafenib hydrate (JAN); Stivarga (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D10161 |
Sarilumab (USAN); Sarilumab (genetical receombination) (JAN); Kevzara (TN) |
(P) unclassified |
| D10185 |
Vortioxetine hydrobromide (JAN/USAN); Brintellix (TN); Trintellix (TN) |
(P) Enzyme: CYP2C9 / CYP induction: CYP2C9 |
| D10218 |
Enzalutamide (JAN/USAN); Xtandi (TN) |
(P) unclassified |
| D10223 |
Ibrutinib (JAN/USAN); Imbruvica (TN) |
(P) unclassified |
| D10243 |
Irbesartan and amlodipine besilate (JP18); Aimix (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D10293 |
Carbidopa, levodopa and entacapone; Stalevo (TN) |
(P) CYP inhibition: CYP2C9 |
| D10298 |
Brimonidine tartrate and timolol maleate; Combigan (TN); Aibeta (TN) |
(P) unclassified |
| D10309 |
Brexpiprazole (JAN/USAN/INN); Rexulti (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D10372 |
Palbociclib (JAN/USAN); Ibrance (TN) |
(P) unclassified |
| D10450 |
Alectinib hydrochloride (JAN); Alecensa (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D10452 |
Cabazitaxel acetonate (JAN); Cabazitaxel acetone; Jevtana (TN) |
(P) unclassified |
| D10466 |
Vonoprazan fumarate (JAN/USAN); Takecab (TN); Voquezna (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D10478 |
Naldemedine tosylate (JAN/USAN); Naldemedine tosilate; Symproic (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D10480 |
Irbesartan and trichlormethiazide; Irtra (TN) |
(P) Enzyme: CYP2C9 / CYP induction: CYP2C9 |
| D10516 |
Aripiprazole hydrate (JAN); Aripiprazole monohydrate; Abilify maintena (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D10524 |
Azilsartan and amlodipine besilate; Zacras (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D10551 |
Ceritinib (JAN/USAN/INN); Zykadia (TN) |
(P) CYP inhibition: CYP2C9 |
| D10564 |
Amenamevir (JAN/INN); Amenalief (TN) |
(P) unclassified |
| D10566 |
Pasireotide pamoate (JAN); Signifor lar (TN) |
(P) unclassified |
| D10633 |
Finerenone (JAN/USAN/INN); Kerendia (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D10643 |
Isavuconazonium sulfate (JAN/USAN); Cresemba (TN) |
(P) unclassified |
| D10679 |
Venetoclax (JAN/USAN/INN); Venclexta (TN) |
(P) unclassified |
| D10688 |
Abemaciclib (JAN/USAN/INN); Verzenio (TN) |
(P) unclassified |
| D10711 |
Pemafibrate (JAN); Parmodia (TN) |
(P) Enzyme: CYP2C9 / CYP induction: CYP2C9 |
| D10762 |
Fosravuconazole L-lysine ethanolate (JAN) |
(P) unclassified |
| D10766 |
Osimertinib mesylate (USAN); Osimertinib mesilate (JAN); Tagrisso (TN) |
(P) unclassified |
| D10774 |
Vonoprazan, amoxicillin and metronidazole; Vonopion (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D10775 |
Vonoprazan, amoxicillin and clarithromycin; Vonosap (TN); Voquenza (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 / CYP induction: CYP3A4 |
| D10780 |
Perampanel hydrate (JAN); Fycompa (TN) |
(P) unclassified |
| D10800 |
Gilteritinib fumarate (JAN/USAN); Xospata (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D10801 |
Letermovir (JAN/USAN/INN); Prevymis (TN) |
(P) CYP induction: CYP2C9 |
| D10805 |
Telmisartan, amlodipine and hydrochlorothiazide; Micatrio (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D10832 |
Darunavir and cobicistat; Prezcobix (TN); Rezolsta (TN) |
(P) unclassified |
| D10854 |
Brinzolamide and brimonidine tartrate; Simbrinza (TN); Ailamide (TN) |
(P) unclassified |
| D10866 |
Brigatinib (JAN/USAN); Alunbrig (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D10889 |
Momelotinib hydrochloride hydrate (JAN); Momelotinib dihydrochloride monohydrate; Ojjaara (TN); Omjjara (TN) |
(P) Enzyme: CYP2C9 CYP3A4 / CYP induction: CYP2C9 CYP3A4 |
| D10891 |
Capmatinib hydrochloride (USAN); Capmatinib hydrochloride hydrate (JAN); Tabrecta (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D10892 |
Esaxerenone (JAN/INN) |
(P) unclassified |
| D10893 |
Acalabrutinib (JAN/USAN/INN); Calquence (TN) |
(P) unclassified |
| D10926 |
Entrectinib (JAN/USAN/INN); Rozlytrek (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D10927 |
Erdafitinib (JAN/USAN/INN); Balversa (TN) |
(P) Enzyme: CYP2C9 CYP3A4 / CYP induction: CYP2C9 CYP3A4 |
| D10990 |
Somatrogon (USAN/INN); Somatrogon (genetical recombination) (JAN); Somatrogon-ghla; Ngenla (TN) |
(P) unclassified |
| D10999 |
Valbenazine tosylate (USAN); Valbenazine tosilate (JAN); Valbenazine ditosylate; Ingrezza (TN); Dysval (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D11012 |
Lorlatinib (JAN/USAN/INN); Lorbrena (TN) |
(P) unclassified |
| D11022 |
Lemborexant (JAN/USAN/INN); Dayvigo (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D11040 |
Apalutamide (JAN/INN); Erleada (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D11045 |
Darolutamide (JAN/USAN/INN); Nebeqa (TN) |
(P) unclassified |
| D11048 |
Upadacitinib hydrate (JAN); Upadacitinib hemihydrate; Rinvoq (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D11053 |
Encorafenib (JAN/USAN/INN); Braftovi (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D11070 |
Tirabrutinib hydrochloride (JAN/USAN); Velexbru (TN) |
(P) unclassified |
| D11072 |
Siponimod fumarate (USAN); Siponimod fumaric acid (JAN); Mayzent (TN) |
(P) Enzyme: CYP2C9 / CYP induction: CYP2C9 |
| D11090 |
Ivosidenib (JAN/USAN/INN); Tibsovo (TN) |
(P) unclassified |
| D11093 |
Avacopan (JAN/USAN/INN); Tavneos (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D11138 |
Larotrectinib sulfate (JAN/USAN); Vitrakvi (TN) |
(P) unclassified |
| D11190 |
Vosoritide (USAN/INN); Vosoritide (genetical recombination) (JAN); Voxzogo (TN) |
(P) unclassified |
| D11194 |
Somapacitan (USAN/INN); Somapacitan (genetical recombination) (JAN); Somapacitan-beco; Sogroya (TN) |
(P) unclassified |
| D11370 |
Fosnetupitant chloride hydrochloride (JAN/USAN); Arokaris (TN) |
(P) unclassified |
| D11371 |
Capivasertib (JAN/USAN); Truqap (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D11382 |
Darunavir, cobicistat, emtricitabine and tenofovir alafenamide; Symtuza (TN) |
(P) unclassified |
| D11400 |
Abrocitinib (JAN/USAN); Cibinqo (TN) |
(P) Enzyme: CYP2C9 / CYP induction: CYP2C9 |
| D11404 |
Asciminib hydrochloride (JAN/USAN); Scemblix (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D11417 |
Pemigatinib (JAN/USAN/INN); Pemazyre (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D11422 |
Zanubrutinib (JAN/USAN/INN); Brukinsa (TN) |
(P) unclassified |
| D11454 |
Repotrectinib (JAN/USAN); Augtyro (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D11485 |
Tazemetostat hydrobromide (JAN/USAN); Tazverik (TN) |
(P) unclassified |
| D11557 |
Tecovirimat hydrate (JAN); Tecovirimat monohydrate; Tpoxx (TN); Tepoxx (TN) |
(P) unclassified |
| D11659 |
Tolvaptan sodium phosphate (JAN); Samtasu (TN) |
(P) unclassified |
| D11662 |
Valemetostat tosilate (JAN); Valemetostat tosylate; Ezharmia (TN) |
(P) unclassified |
| D11674 |
Berotralstat hydrochloride (JAN/USAN); Orladeyo (TN) |
(P) CYP inhibition: CYP3A4 |
| D11713 |
Selpercatinib (JAN/USAN/INN); Retevmo (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D11725 |
Futibatinib (JAN/USAN/INN); Lytgobi (TN) |
(P) unclassified |
| D11804 |
Aspirin and vonoprazan; Cabpirin (TN) |
(P) unclassified |
| D11816 |
Belumosudil mesylate (USAN); Belumosudil mesilate (JAN); Rezurock (TN) |
(P) unclassified |
| D11887 |
Daridorexant hydrochloride (JAN/USAN); Quviviq (TN) |
(P) unclassified |
| D11920 |
Pimitespib (JAN); Jeselhy (TN) |
(P) unclassified |
| D11970 |
Ritlecitinib tosylate (USAN); Ritlecitinib tosilate (JAN); Litfulo (TN) |
(P) unclassified |
| D11977 |
Fruquintinib (JAN/USAN); Fruzaqla (TN) |
(P) Enzyme: CYP2C9 / CYP induction: CYP2C9 |
| D12047 |
Drospirenone and estetrol; Nextstellis (TN); Drovelis (TN); Lydisilka (TN); Alyssa (TN) |
(P) unclassified |
| D12050 |
Pirtobrutinib (JAN/USAN); Jaypirca (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D12055 |
Sotorasib (JAN/USAN); Lumakras (TN) |
(P) unclassified |
| D12245 |
Lazertinib mesylate (USAN); Lazertinib mesilate hydrate (JAN); Lazcluze (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D12252 |
Iptacopan hydrochloride (USAN); Iptacopan hydrochloride hydrate (JAN); Iptacopan hydrochloride monohydrate; Fabhalta (TN) |
(P) unclassified |
| D12265 |
Mavacamten (JAN/USAN/INN); Camzyos (TN) |
(P) Enzyme: CYP2C9 / CYP induction: CYP2C9 |
| D12311 |
Bortezomib hydrate (JAN) |
(P) unclassified |
| D12353 |
Ensitrelvir fumarate (USAN); Ensitrelvir fumaric acid (JAN); Xocova (TN) |
(P) unclassified |
| D12437 |
Ripasudil hydrochloride and brimonidine tartrate; Gla-alpha (TN) |
(P) unclassified |
| D12494 |
Foslevodopa and foscarbidopa; Vyalev (TN) |
(P) unclassified |
| D12586 |
Mifepristone and misoprostol; Mefeego (TN) |
(CI,P) unclassified |
| D12963 |
Macitentan and tadalafil; Opsynvi (TN); Yuvanci (TN) |
(CI,P) Enzyme: CYP2C9 / CYP induction: CYP2C9 |
