Kanei-Ishii C, Nomura T, Takagi T, Watanabe N, Nakayama KI, Ishii S

Fbxw7 acts as an E3 ubiquitin ligase that targets c-Myb for nemo-like kinase (NLK)-induced degradation.

J Biol Chem 283:30540-8 (2008)
DOI:10.1074/jbc.M804340200

[hsa:55294]

Inuzuka H, Shaik S, Onoyama I, Gao D, Tseng A, Maser RS, Zhai B, Wan L, Gutierrez A, Lau AW, Xiao Y, Christie AL, Aster J, Settleman J, Gygi SP, Kung AL, Look T, Nakayama KI, DePinho RA, Wei W

SCFFBW7 regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction.

Nature 471:104-9 (2011)
DOI:10.1038/nature09732

[hsa:55294] [mmu:50754]

Strohmaier H, Spruck CH, Kaiser P, Won KA, Sangfelt O, Reed SI

Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line.

Nature 413:316-22 (2001)
DOI:10.1038/35095076

[hsa:55294]