KEGG   ORTHOLOGY: K04650
Entry
K04650                      KO                                     

Name
NCOR1, N-CoR
Definition
nuclear receptor co-repressor 1
Pathway
ko01522  Endocrine resistance
ko04919  Thyroid hormone signaling pathway
ko05202  Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    K04650  NCOR1, N-CoR; nuclear receptor co-repressor 1
 09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    K04650  NCOR1, N-CoR; nuclear receptor co-repressor 1
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    K04650  NCOR1, N-CoR; nuclear receptor co-repressor 1
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins
    K04650  NCOR1, N-CoR; nuclear receptor co-repressor 1
Protein phosphatases and associated proteins [BR:ko01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     K04650  NCOR1, N-CoR; nuclear receptor co-repressor 1
Genes
HSA: 9611(NCOR1)
PTR: 468370(NCOR1)
GGO: 101148051(NCOR1)
PON: 100449226(NCOR1)
NLE: 100598888(NCOR1)
MCC: 696351(NCOR1)
MCF: 101925549(NCOR1)
CSAB: 103242451(NCOR1)
RRO: 104681440(NCOR1)
RBB: 108522162(NCOR1)
CJC: 100414861(NCOR1)
SBQ: 101045587(NCOR1)
MMU: 20185(Ncor1)
MCAL: 110305303(Ncor1)
MPAH: 110331333(Ncor1)
RNO: 54299(Ncor1)
MUN: 110549803(Ncor1)
CGE: 100760832(Ncor1)
NGI: 103726371(Ncor1)
HGL: 101715929(Ncor1)
CCAN: 109699495(Ncor1)
OCU: 100354310(NCOR1)
TUP: 102486196(NCOR1)
CFA: 479515(NCOR1)
VVP: 112924930(NCOR1)
AML: 100482935(NCOR1)
UAH: 113271257(NCOR1)
ORO: 101372646(NCOR1)
ELK: 111139473
FCA: 101095293(NCOR1)
PTG: 102951947(NCOR1)
PPAD: 109245811(NCOR1)
AJU: 106981419(NCOR1)
BTA: 507663(NCOR1)
BOM: 102267545(NCOR1)
BIU: 109573398(NCOR1)
BBUB: 102399672(NCOR1)
CHX: 102188080(NCOR1)
OAS: 101117774(NCOR1)
SSC: 100628075(NCOR1)
CFR: 102518187(NCOR1)
CDK: 105085104(NCOR1)
BACU: 102997482(NCOR1)
LVE: 103077563(NCOR1)
OOR: 101286859(NCOR1)
DLE: 111167742(NCOR1)
PCAD: 102986914(NCOR1)
ECB: 100063285(NCOR1)
EPZ: 103560478(NCOR1)
EAI: 106838856(NCOR1)
MYB: 102249238(NCOR1)
MYD: 102765108(NCOR1)
MNA: 107524503(NCOR1)
HAI: 109382177
DRO: 112308471(NCOR1)
PALE: 102894128(NCOR1)
RAY: 107511056(NCOR1)
MJV: 108403991(NCOR1)
LAV: 100669709(NCOR1)
TMU: 101359018
MDO: 100014037(NCOR1)
SHR: 100914315(NCOR1)
PCW: 110222197(NCOR1)
OAA: 100076684(NCOR1)
GGA: 417598(NCOR1)
CJO: 107322409(NCOR1)
NMEL: 110407628(NCOR1)
APLA: 101799868(NCOR1)
ACYG: 106045767(NCOR1)
TGU: 100230035(NCOR1)
LSR: 110467691(NCOR1)
SCAN: 103820146(NCOR1)
GFR: 102041117(NCOR1)
FAB: 101806968(NCOR1)
PHI: 102107181(NCOR1)
PMAJ: 107212775(NCOR1)
CCAE: 111937795(NCOR1)
CCW: 104691036(NCOR1)
ETL: 114061257(NCOR1)
FPG: 101912637(NCOR1)
FCH: 102047526(NCOR1)
CLV: 102095752(NCOR1)
EGZ: 104121909(NCOR1)
NNI: 104012186(NCOR1)
ACUN: 113487111(NCOR1)
PADL: 103920797(NCOR1)
AAM: 106493755(NCOR1)
ASN: 102368392(NCOR1)
AMJ: 102560876(NCOR1)
PSS: 102448548(NCOR1)
CMY: 102936803(NCOR1)
CPIC: 101947868(NCOR1)
PVT: 110087388(NCOR1)
PBI: 103050724(NCOR1)
PMUA: 114585390(NCOR1)
GJA: 107119554(NCOR1)
XLA: 108707936(ncor1.L) 398304(ncor1.S)
XTR: 613105(ncor1)
DRE: 393246(ncor1)
CCAR: 109072913
IPU: 108259869(ncor1)
PHYP: 113531303
AMEX: 103035566(ncor1)
EEE: 113589990(ncor1)
TRU: 101063896(ncor1)
LCO: 104923453(ncor1)
MZE: 101469949(ncor1)
ONL: 100702761(ncor1)
OLA: 105355657(ncor1)
XMA: 102229406(ncor1)
XCO: 114152811(ncor1)
PRET: 103476039(ncor1)
CVG: 107091737(ncor1)
NFU: 107386639(ncor1)
KMR: 108233829(ncor1)
ALIM: 106525394(ncor1)
AOCE: 111575203(ncor1)
CSEM: 103394907(ncor1)
POV: 109628545(ncor1)
LCF: 108893218(ncor1)
SDU: 111222173(ncor1)
SLAL: 111663916(ncor1)
HCQ: 109531079(ncor1)
BPEC: 110165109(ncor1)
MALB: 109960446(ncor1)
SASA: 106567980(ncor1)
OTW: 112257859
SALP: 111980519
ELS: 105027552(ncor1)
SFM: 108936158(ncor1)
PKI: 111854760(ncor1)
LCM: 102367610(NCOR1)
BFO: 118426390
CIN: 100177691
DME: Dmel_CG4013(Smr)
DER: 6551120
DSI: Dsimw501_GD15920(Dsim_GD15920)
DPE: 6603228
DMN: 108165262
DAZ: 108618339
DNV: 108655912
DHE: 111602422
AAG: 110679171
AME: 724535
BIM: 100743966
BTER: 100643368
CCAL: 108628027
NVI: 100122466
BMY: Bm1_08775
HMG: 101236675
 » show all
Reference
PMID:9724795
  Authors
Wang J, Hoshino T, Redner RL, Kajigaya S, Liu JM
  Title
ETO, fusion partner in t(8;21) acute myeloid leukemia, represses transcription by interaction with the human N-CoR/mSin3/HDAC1 complex.
  Journal
Proc Natl Acad Sci U S A 95:10860-5 (1998)
DOI:10.1073/pnas.95.18.10860
  Sequence
[hsa:9611]
Reference
  Authors
Hayakawa T, Nakayama J
  Title
Physiological roles of class I HDAC complex and histone demethylase.
  Journal
J Biomed Biotechnol 2011:129383 (2011)
DOI:10.1155/2011/129383
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