KEGG   PATHWAY: mmma05022
Entry
mmma05022                   Pathway                                
Name
Pathways of neurodegeneration - multiple diseases - Marmota marmota marmota (Alpine marmot)
Description
Neurodegeneration is generally defined as progressive, irreversible loss of neurons, which may affect either the peripheral or central nervous system (CNS). Neurodegenerative diseases (NDs) include highly debilitating illnesses, such as Alzheimer (AD), Parkinson disease (PD), amyotrophic lateral sclerosis, Huntington disease, spinocerebellar ataxias, and prion diseases (PrD). The hallmark event, which is thought to be at the root of these diseases, is the progressive accumulation of misfolded protein aggregates. Major basic processes include abnormal protein dynamics due to deficiency of the ubiquitin-proteosome-autophagy system, oxidative stress and free radical formation, endoplasmic reticulum stress, mitochondrial dysfunction and (secondary) disruptions of axonal transport.
Class
Human Diseases; Neurodegenerative disease
Pathway map
mmma05022  Pathways of neurodegeneration - multiple diseases
mmma05022

Organism
Marmota marmota marmota (Alpine marmot) [GN:mmma]
Gene
107136416  amyloid-beta precursor protein isoform X1 [KO:K04520]
107160525  Mapt; microtubule-associated protein tau isoform X2 [KO:K04380]
107141208  Snca; alpha-synuclein [KO:K04528]
107155506  TAR DNA-binding protein 43 isoform X1 [KO:K23600]
107146978  Fus; RNA-binding protein FUS isoform X3 [KO:K13098]
107136431  Sod1; superoxide dismutase [Cu-Zn] isoform X2 [KO:K04565] [EC:1.15.1.1]
107149756  superoxide dismutase [Cu-Zn]-like [KO:K04565] [EC:1.15.1.1]
107146896  Atxn2l; ataxin-2-like protein isoform X3 [KO:K23625]
107156439  Atxn2; ataxin-2 isoform X7 [KO:K23625]
107139096  Htt; huntingtin isoform X1 [KO:K04533]
107150929  Atxn1l; ataxin-1-like [KO:K23616]
107149271  Atxn1; ataxin-1 [KO:K23616]
107149959  Atxn3; ataxin-3 isoform X1 [KO:K11863] [EC:3.4.22.-]
107139756  major prion protein [KO:K05634]
107135940  Chrm1; muscarinic acetylcholine receptor M1 [KO:K04129]
107150312  Chrm3; muscarinic acetylcholine receptor M3 [KO:K04131]
107137816  Chrm5; muscarinic acetylcholine receptor M5 [KO:K04133]
107156988  Sptbn2; spectrin beta chain, non-erythrocytic 2 isoform X2 [KO:K23932]
107156011  Grm1; metabotropic glutamate receptor 1 [KO:K04603]
107135439  Grm5; metabotropic glutamate receptor 5 isoform X1 [KO:K04604]
107148216  guanine nucleotide-binding protein G(q) subunit alpha [KO:K04634]
107153167  Prkn; E3 ubiquitin-protein ligase parkin isoform X1 [KO:K04556] [EC:2.3.2.31]
107135966  Plcb3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 isoform X1 [KO:K05858] [EC:3.1.4.11]
107138232  Plcb2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X1 [KO:K05858] [EC:3.1.4.11]
107145524  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X3 [KO:K05858] [EC:3.1.4.11]
107145453  Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 [KO:K05858] [EC:3.1.4.11]
107138082  Plcg1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [KO:K01116] [EC:3.1.4.11]
107158309  Prkca; protein kinase C alpha type [KO:K02677] [EC:2.7.11.13]
107146552  Prkcb; protein kinase C beta type isoform X1 [KO:K19662] [EC:2.7.11.13]
107158898  Prkcg; protein kinase C gamma type [KO:K19663] [EC:2.7.11.13]
107136740  Trpc3; short transient receptor potential channel 3 isoform X3 [KO:K04966]
107147834  Sigmar1; sigma non-opioid intracellular receptor 1 isoform X1 [KO:K20719]
107150041  Itpr1; inositol 1,4,5-trisphosphate receptor type 1 isoform X11 [KO:K04958]
107152732  Itpr2; inositol 1,4,5-trisphosphate receptor type 2 isoform X2 [KO:K04959]
107143606  Itpr3; inositol 1,4,5-trisphosphate receptor type 3 isoform X1 [KO:K04960]
107151657  Ryr1; LOW QUALITY PROTEIN: ryanodine receptor 1 [KO:K04961]
107157936  Ryr2; ryanodine receptor 2 [KO:K04962]
107137664  Ryr3; ryanodine receptor 3 [KO:K04963]
107159414  Pdyn; proenkephalin-B [KO:K15840]
107157969  Dlg4; disks large homolog 4 isoform X1 [KO:K11828]
107159190  Grin1; glutamate receptor ionotropic, NMDA 1 isoform X1 [KO:K05208]
107146628  Grin2a; glutamate receptor ionotropic, NMDA 2A [KO:K05209]
107152685  Grin2b; glutamate receptor ionotropic, NMDA 2B [KO:K05210]
107157872  Grin2c; glutamate receptor ionotropic, NMDA 2C [KO:K05211]
107151575  Grin2d; glutamate receptor ionotropic, NMDA 2D [KO:K05212]
107148089  Gria1; glutamate receptor 1 isoform X1 [KO:K05197]
107141203  Gria2; glutamate receptor 2 isoform X4 [KO:K05198]
107153037  Gria3; glutamate receptor 3 [KO:K05199]
107145895  Gria4; glutamate receptor 4 isoform X2 [KO:K05200]
107159103  Cacna1b; LOW QUALITY PROTEIN: voltage-dependent N-type calcium channel subunit alpha-1B [KO:K04849]
107154890  Cacna1c; voltage-dependent L-type calcium channel subunit alpha-1C isoform X1 [KO:K04850]
107149619  Cacna1d; voltage-dependent L-type calcium channel subunit alpha-1D isoform X1 [KO:K04851]
107159825  Cacna1f; voltage-dependent L-type calcium channel subunit alpha-1F isoform X1 [KO:K04853]
107140653  Cacna1s; voltage-dependent L-type calcium channel subunit alpha-1S [KO:K04857]
107147036  Stx1a; syntaxin-1A [KO:K04560]
107148489  CHRNA7-FAM7A fusion protein isoform X1 [KO:K04809]
107146890  Atp2a1; sarcoplasmic/endoplasmic reticulum calcium ATPase 1 [KO:K05853] [EC:7.2.2.10]
107159393  Atp2a3; sarcoplasmic/endoplasmic reticulum calcium ATPase 3 isoform X2 [KO:K05853] [EC:7.2.2.10]
107156426  Atp2a2; sarcoplasmic/endoplasmic reticulum calcium ATPase 2 [KO:K05853] [EC:7.2.2.10]
107148860  Psen1; presenilin-1 isoform X1 [KO:K04505] [EC:3.4.23.-]
107140486  Psen2; presenilin-2 isoform X1 [KO:K04522] [EC:3.4.23.-]
107142897  Derl1; derlin-1 [KO:K11519]
107133752  LOW QUALITY PROTEIN: transitional endoplasmic reticulum ATPase-like [KO:K13525]
107145357  Uba52; ubiquitin-60S ribosomal protein L40 isoform X1 [KO:K02927]
107137278  Rps27a; ubiquitin-40S ribosomal protein S27a [KO:K02977]
107142203  ubiquitin-40S ribosomal protein S27a-like [KO:K02977]
107143733  ubiquitin-40S ribosomal protein S27a-like [KO:K02977]
107147107  Psma6; proteasome subunit alpha type-6 [KO:K02730] [EC:3.4.25.1]
107146203  Psma2; proteasome subunit alpha type-2 [KO:K02726] [EC:3.4.25.1]
107137908  Psma4; proteasome subunit alpha type-4 [KO:K02728] [EC:3.4.25.1]
107136437  Psma7; proteasome subunit alpha type-7 [KO:K02731] [EC:3.4.25.1]
107139410  Psma8; proteasome subunit alpha-type 8 isoform X2 [KO:K02731] [EC:3.4.25.1]
107134499  proteasome subunit alpha type-7-like [KO:K02731] [EC:3.4.25.1]
107158620  Psma5; proteasome subunit alpha type-5 isoform X1 [KO:K02729] [EC:3.4.25.1]
107135668  Psma1; proteasome subunit alpha type-1 isoform X1 [KO:K02725] [EC:3.4.25.1]
107138315  Psma3; proteasome subunit alpha type-3 isoform X1 [KO:K02727] [EC:3.4.25.1]
107152020  proteasome subunit beta type-6-like [KO:K02738] [EC:3.4.25.1]
107159412  Psmb6; proteasome subunit beta type-6 [KO:K02738] [EC:3.4.25.1]
107152100  Psmb7; proteasome subunit beta type-7 [KO:K02739] [EC:3.4.25.1]
107160021  Psmb3; proteasome subunit beta type-3 [KO:K02735] [EC:3.4.25.1]
107141960  Psmb2; proteasome subunit beta type-2 isoform X1 [KO:K02734] [EC:3.4.25.1]
107148113  Psmb5; proteasome subunit beta type-5 [KO:K02737] [EC:3.4.25.1]
107137384  proteasome subunit beta type-1 [KO:K02732] [EC:3.4.25.1]
107153084  Psmb1; LOW QUALITY PROTEIN: proteasome subunit beta type-1 [KO:K02732] [EC:3.4.25.1]
107156804  Psmb4; proteasome subunit beta type-4 [KO:K02736] [EC:3.4.25.1]
107152391  26S proteasome regulatory subunit 7-like [KO:K03061]
107149837  Psmc1; 26S proteasome regulatory subunit 4 [KO:K03062]
107142327  LOW QUALITY PROTEIN: 26S proteasome regulatory subunit 4-like [KO:K03062]
107151465  Psmc4; 26S proteasome regulatory subunit 6B [KO:K03063]
107138279  Psmc6; 26S proteasome regulatory subunit 10B [KO:K03064]
107135815  Psmc3; 26S proteasome regulatory subunit 6A isoform X1 [KO:K03065]
107158336  Psmc5; 26S proteasome regulatory subunit 8 isoform X1 [KO:K03066]
107154323  Psmd2; 26S proteasome non-ATPase regulatory subunit 2 [KO:K03028]
107138782  Psmd1; 26S proteasome non-ATPase regulatory subunit 1 [KO:K03032]
107150628  Psmd3; 26S proteasome non-ATPase regulatory subunit 3 [KO:K03033]
107156410  Psmd9; 26S proteasome non-ATPase regulatory subunit 9 isoform X3 [KO:K06693]
107158356  Psmd12; 26S proteasome non-ATPase regulatory subunit 12 [KO:K03035]
107155158  Psmd11; 26S proteasome non-ATPase regulatory subunit 11 isoform X1 [KO:K03036]
107149672  Psmd6; 26S proteasome non-ATPase regulatory subunit 6 isoform X2 [KO:K03037]
107150939  Psmd7; 26S proteasome non-ATPase regulatory subunit 7 [KO:K03038]
107157120  Psmd13; 26S proteasome non-ATPase regulatory subunit 13 [KO:K03039]
107156810  Psmd4; 26S proteasome non-ATPase regulatory subunit 4 isoform X1 [KO:K03029]
107136883  Psmd14; 26S proteasome non-ATPase regulatory subunit 14 isoform X1 [KO:K03030]
107142356  26S proteasome non-ATPase regulatory subunit 8 [KO:K03031]
107151495  Psmd8; 26S proteasome non-ATPase regulatory subunit 8 [KO:K03031]
107136373  Adrm1; proteasomal ubiquitin receptor ADRM1 isoform X1 [KO:K06691]
125611362  Sem1; 26S proteasome complex subunit SEM1 [KO:K10881]
107139207  Uchl1; ubiquitin carboxyl-terminal hydrolase isozyme L1 isoform X2 [KO:K05611] [EC:3.4.19.12]
107144321  Uba1; ubiquitin-like modifier-activating enzyme 1 [KO:K03178] [EC:6.2.1.45]
107133779  LOW QUALITY PROTEIN: ubiquitin-like modifier-activating enzyme 1 [KO:K03178] [EC:6.2.1.45]
107143469  Uba7; ubiquitin-like modifier-activating enzyme 7 isoform X1 [KO:K10698] [EC:6.2.1.45]
107154681  Ube2l3; ubiquitin-conjugating enzyme E2 L3 isoform X1 [KO:K04552] [EC:2.3.2.23]
107135840  Ube2l6; ubiquitin/ISG15-conjugating enzyme E2 L6 isoform X2 [KO:K04553] [EC:2.3.2.23]
107155599  Ube2j2; ubiquitin-conjugating enzyme E2 J2 [KO:K04554] [EC:2.3.2.23]
107153778  Ube2j1; ubiquitin-conjugating enzyme E2 J1 [KO:K10578] [EC:2.3.2.23]
107136543  Ube2g2; ubiquitin-conjugating enzyme E2 G2 isoform X1 [KO:K04555] [EC:2.3.2.23]
107159323  Ube2g1; ubiquitin-conjugating enzyme E2 G1 [KO:K10575] [EC:2.3.2.23]
107156181  ubiquitin-conjugating enzyme E2 G1 [KO:K10575] [EC:2.3.2.23]
107144509  Gpr37; prosaposin receptor GPR37 [KO:K04243]
107154720  Septin5; septin-5 isoform X1 [KO:K04557]
107143175  synphilin-1 isoform X1 [KO:K04558]
107152089  Hspa5; endoplasmic reticulum chaperone BiP [KO:K09490] [EC:3.6.4.10]
107137813  Vapb; vesicle-associated membrane protein-associated protein B/C [KO:K10707]
107147457  Atf6; cyclic AMP-dependent transcription factor ATF-6 alpha isoform X2 [KO:K09054]
107140132  Ddit3; DNA damage-inducible transcript 3 protein [KO:K04452]
107137367  DNA damage-inducible transcript 3 protein-like [KO:K04452]
107154590  Xbp1; LOW QUALITY PROTEIN: X-box-binding protein 1 [KO:K09027]
107158342  Ern1; serine/threonine-protein kinase/endoribonuclease IRE1 [KO:K08852] [EC:2.7.11.1 3.1.26.-]
107159171  Traf2; TNF receptor-associated factor 2 isoform X2 [KO:K03173] [EC:2.3.2.27]
107155636  Map3k5; mitogen-activated protein kinase kinase kinase 5 isoform X1 [KO:K04426] [EC:2.7.11.25]
107157355  Map2k7; dual specificity mitogen-activated protein kinase kinase 7 isoform X1 [KO:K04431] [EC:2.7.12.2]
107159793  Mapk9; mitogen-activated protein kinase 9 isoform X1 [KO:K04440] [EC:2.7.11.24]
107153372  Mapk8; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
107153644  Mapk10; mitogen-activated protein kinase 10 isoform X1 [KO:K04440] [EC:2.7.11.24]
107144171  LOW QUALITY PROTEIN: mitogen-activated protein kinase 8-like [KO:K04440] [EC:2.7.11.24]
107151641  Map3k10; mitogen-activated protein kinase kinase kinase 10 [KO:K04418] [EC:2.7.11.25]
107159738  Eif2ak3; eukaryotic translation initiation factor 2-alpha kinase 3 [KO:K08860] [EC:2.7.11.1]
107146232  Eif2s1; eukaryotic translation initiation factor 2 subunit 1 [KO:K03237]
107155865  Atf4; cyclic AMP-dependent transcription factor ATF-4 [KO:K04374]
107146304  Slc6a3; sodium-dependent dopamine transporter [KO:K05036]
107142167  Pink1; serine/threonine-protein kinase PINK1, mitochondrial isoform X1 [KO:K05688] [EC:2.7.11.1]
107156880  Ndufv1; NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial [KO:K03942] [EC:7.1.1.2]
107139635  Ndufv2; NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial [KO:K03943] [EC:7.1.1.2]
107136511  Ndufv3; NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial isoform X1 [KO:K03944]
107152995  Ndufa1; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 [KO:K03945]
107146270  NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1-like [KO:K03945]
107141755  Ndufa2; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 [KO:K03946]
107158928  Ndufa3; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 [KO:K03947]
107144474  Ndufa4; cytochrome c oxidase subunit NDUFA4 [KO:K03948]
107140143  Ndufa4l2; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2 isoform X1 [KO:K03948]
107144505  Ndufa5; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 [KO:K03949]
107155829  Ndufa6; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 [KO:K03950]
107157374  Ndufa7; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 [KO:K03951]
107152121  Ndufa8; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 [KO:K03952]
107154983  Ndufa9; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial [KO:K03953]
107138852  Ndufa10; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial [KO:K03954]
107146550  Ndufab1; acyl carrier protein, mitochondrial [KO:K03955]
107157461  Ndufa11; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 [KO:K03956]
107140004  Ndufa12; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 isoform X1 [KO:K11352]
107145383  Ndufa13; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 [KO:K11353]
107144262  NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 [KO:K03957]
107149970  Ndufb1; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 [KO:K03957]
107149001  Ndufb2; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial isoform X2 [KO:K03958]
107138601  Ndufb3; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 [KO:K03959]
107151079  NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3-like [KO:K03959]
107143262  Ndufb4; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 [KO:K03960]
107152489  NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4-like [KO:K03960]
107149458  Ndufb5; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial [KO:K03961]
107147859  Ndufb6; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 [KO:K03962]
107145272  Ndufb7; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 [KO:K03963]
107149806  Ndufb8; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial isoform X1 [KO:K03964]
107142910  Ndufb9; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 isoform X1 [KO:K03965]
107146729  Ndufb10; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 [KO:K03966]
107138463  Ndufb11; LOW QUALITY PROTEIN: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial [KO:K11351]
107135241  NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial [KO:K11351]
107138634  Ndufs1; NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial isoform X1 [KO:K03934] [EC:7.1.1.2]
107147471  Ndufs2; NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial [KO:K03935] [EC:7.1.1.2]
107135819  Ndufs3; NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial [KO:K03936] [EC:7.1.1.2]
107151897  Ndufs4; NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial [KO:K03937]
107144351  NADH dehydrogenase [ubiquinone] iron-sulfur protein 5-like [KO:K03938]
107141924  Ndufs5; NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 [KO:K03938]
107146364  Ndufs6; NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial [KO:K03939]
107157247  Ndufs7; NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial isoform X1 [KO:K03940] [EC:7.1.1.2]
107157021  Ndufs8; NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial isoform X1 [KO:K03941] [EC:7.1.1.2]
107136771  Ndufc1; NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial [KO:K03967]
107135475  Ndufc2; NADH dehydrogenase [ubiquinone] 1 subunit C2 [KO:K03968]
107146296  Sdha; succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial [KO:K00234] [EC:1.3.5.1]
107141579  Sdhb; succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial [KO:K00235] [EC:1.3.5.1]
107147466  Sdhc; succinate dehydrogenase cytochrome b560 subunit, mitochondrial isoform X1 [KO:K00236]
107145856  Sdhd; succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial [KO:K00237]
107150640  succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial-like [KO:K00237]
107151812  LOW QUALITY PROTEIN: succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial-like [KO:K00237]
107149921  LOW QUALITY PROTEIN: cytochrome b-c1 complex subunit Rieske, mitochondrial-like [KO:K00411] [EC:7.1.1.8]
107143017  cytochrome c1, heme protein, mitochondrial [KO:K00413]
107143515  cytochrome b-c1 complex subunit 1, mitochondrial [KO:K00414]
107146855  cytochrome b-c1 complex subunit 2, mitochondrial [KO:K00415]
107141806  cytochrome b-c1 complex subunit 6, mitochondrial isoform X1 [KO:K00416]
107142519  cytochrome b-c1 complex subunit 7 isoform X1 [KO:K00417]
107148123  cytochrome b-c1 complex subunit 8 [KO:K00418]
107154580  cytochrome b-c1 complex subunit 9 [KO:K00419]
107157256  cytochrome b-c1 complex subunit 10 [KO:K00420]
107150843  cytochrome c oxidase subunit 4 isoform 1, mitochondrial isoform X2 [KO:K02263]
107134718  cytochrome c oxidase subunit 4 isoform 2, mitochondrial-like [KO:K02263]
107159065  cytochrome c oxidase subunit 4 isoform 2, mitochondrial [KO:K02263]
107137948  cytochrome c oxidase subunit 5A, mitochondrial [KO:K02264]
107154122  cytochrome c oxidase subunit 5B, mitochondrial [KO:K02265]
107148749  LOW QUALITY PROTEIN: cytochrome c oxidase subunit 5B, mitochondrial-like [KO:K02265]
107146984  cytochrome c oxidase subunit 6A2, mitochondrial [KO:K02266]
107158712  cytochrome c oxidase subunit 6A1, mitochondrial [KO:K02266]
107147180  cytochrome c oxidase subunit 6B1-like [KO:K02267]
107158929  cytochrome c oxidase subunit 6B2 [KO:K02267]
107151834  cytochrome c oxidase subunit 6B1 [KO:K02267]
107142829  cytochrome c oxidase subunit 6C [KO:K02268]
107137328  cytochrome c oxidase subunit 7A-related protein, mitochondrial [KO:K02270]
107137972  cytochrome c oxidase subunit 7A-related protein, mitochondrial [KO:K02270]
107149546  cytochrome c oxidase subunit 7A-related protein, mitochondrial-like [KO:K02270]
107151835  cytochrome c oxidase subunit 7A1, mitochondrial [KO:K02270]
107153341  cytochrome c oxidase subunit 7A2, mitochondrial isoform X2 [KO:K02270]
107134143  cytochrome c oxidase subunit 7A2, mitochondrial-like [KO:K02270]
107160422  cytochrome c oxidase subunit 7A-related protein, mitochondrial-like [KO:K02270]
107138951  cytochrome c oxidase subunit 7B2, mitochondrial [KO:K02271]
107159289  cytochrome c oxidase subunit 7B, mitochondrial [KO:K02271]
107152336  cytochrome c oxidase subunit 7C, mitochondrial [KO:K02272]
107135954  cytochrome c oxidase subunit 8A, mitochondrial [KO:K02273]
107157121  cytochrome c oxidase subunit 8B, mitochondrial-like [KO:K02273]
107139527  Atp5f1a; ATP synthase subunit alpha, mitochondrial [KO:K02132]
107140159  Atp5f1b; ATP synthase subunit beta, mitochondrial [KO:K02133] [EC:7.1.2.2]
107150226  Atp5f1c; ATP synthase subunit gamma, mitochondrial isoform X1 [KO:K02136]
107157405  Atp5f1d; ATP synthase subunit delta, mitochondrial [KO:K02134]
107148314  LOW QUALITY PROTEIN: ATP synthase subunit epsilon, mitochondrial-like [KO:K02135]
107138216  Atp5f1e; ATP synthase subunit epsilon, mitochondrial [KO:K02135]
107156135  Atp5pb; ATP synthase F(0) complex subunit B1, mitochondrial [KO:K02127]
107136940  Atp5mc3; ATP synthase F(0) complex subunit C3, mitochondrial [KO:K02128]
107150479  Atp5mc1; ATP synthase F(0) complex subunit C1, mitochondrial isoform X2 [KO:K02128]
107148754  Atp5mc2; ATP synthase F(0) complex subunit C2, mitochondrial [KO:K02128]
107152831  LOW QUALITY PROTEIN: ATP synthase F(0) complex subunit C3, mitochondrial-like [KO:K02128]
107147554  ATP synthase F(0) complex subunit C3, mitochondrial-like [KO:K02128]
107143163  ATP synthase F(0) complex subunit C2, mitochondrial [KO:K02128]
125613532  ATP synthase F(0) complex subunit C1, mitochondrial-like [KO:K02128]
107157798  Atp5pd; ATP synthase subunit d, mitochondrial [KO:K02138]
107136450  Atp5po; ATP synthase subunit O, mitochondrial isoform X1 [KO:K02137]
107136415  Atp5pf; ATP synthase-coupling factor 6, mitochondrial isoform X1 [KO:K02131]
107139463  Bcl2; apoptosis regulator Bcl-2 isoform X1 [KO:K02161]
107146908  LOW QUALITY PROTEIN: voltage-dependent anion-selective channel protein 1-like [KO:K05862]
107148006  Vdac1; voltage-dependent anion-selective channel protein 1 [KO:K05862]
107151364  Tomm40; mitochondrial import receptor subunit TOM40 homolog isoform X2 [KO:K11518]
107147469  Tomm40l; mitochondrial import receptor subunit TOM40B isoform X2 [KO:K11518]
107154744  Mcu; calcium uniporter protein, mitochondrial [KO:K20858]
107137302  Calm2; calmodulin-2 isoform X1 [KO:K02183]
107149860  Calm1; calmodulin-1 [KO:K02183]
107150315  calmodulin-like [KO:K02183]
107150317  calmodulin-like protein 3 [KO:K02183]
107151326  Calm3; calmodulin-3 [KO:K02183]
107137985  Calml4; LOW QUALITY PROTEIN: calmodulin-like protein 4 [KO:K02183]
107153315  calmodulin-like [KO:K02183]
107155450  Calml6; calmodulin-like protein 6 [KO:K02183]
107141348  Ppp3ca; protein phosphatase 3 catalytic subunit alpha isoform X1 [KO:K04348] [EC:3.1.3.16]
107153931  Ppp3cc; serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform isoform X1 [KO:K04348] [EC:3.1.3.16]
107154781  Ppp3cb; serine/threonine-protein phosphatase 2B catalytic subunit beta isoform isoform X1 [KO:K04348] [EC:3.1.3.16]
107137223  Ppp3r1; calcineurin subunit B type 1 [KO:K06268]
107147622  Ppp3r2; calcineurin subunit B type 2 [KO:K06268]
107135974  Bad; bcl2-associated agonist of cell death [KO:K02158]
107147374  Faslg; tumor necrosis factor ligand superfamily member 6 [KO:K04389]
107153328  Fas; tumor necrosis factor receptor superfamily member 6 [KO:K04390]
107157044  Fadd; FAS-associated death domain protein [KO:K02373]
107138607  Casp8; caspase-8 isoform X1 [KO:K04398] [EC:3.4.22.61]
107155037  Bid; BH3-interacting domain death agonist isoform X1 [KO:K04726]
107151268  Bax; apoptosis regulator BAX isoform X1 [KO:K02159]
107143808  Bak1; bcl-2 homologous antagonist/killer [KO:K14021]
107148551  Lrrk2; leucine-rich repeat serine/threonine-protein kinase 2 isoform X1 [KO:K08844] [EC:2.7.11.1]
107154234  Htra2; serine protease HTRA2, mitochondrial isoform X1 [KO:K08669] [EC:3.4.21.108]
107146489  Trap1; heat shock protein 75 kDa, mitochondrial [KO:K09488]
107159648  Vdac3; voltage-dependent anion-selective channel protein 3 isoform X1 [KO:K15041]
107136662  Slc25a31; ADP/ATP translocase 4 [KO:K05863]
107142667  Slc25a4; ADP/ATP translocase 1 [KO:K05863]
107153003  Slc25a5; ADP/ATP translocase 2 [KO:K05863]
107158131  Ppif; peptidyl-prolyl cis-trans isomerase F, mitochondrial [KO:K09565] [EC:5.2.1.8]
107146118  cytochrome c, somatic [KO:K08738]
125618140  LOW QUALITY PROTEIN: cytochrome c, testis-specific-like [KO:K08738]
107161017  cytochrome c, somatic [KO:K08738]
107149067  cytochrome c, somatic-like [KO:K08738]
107135575  cytochrome c, somatic-like [KO:K08738]
107151095  cytochrome c, somatic-like [KO:K08738]
107136200  cytochrome c, somatic-like [KO:K08738]
107139684  Apaf1; LOW QUALITY PROTEIN: apoptotic protease-activating factor 1 [KO:K02084]
107142215  Casp9; caspase-9 [KO:K04399] [EC:3.4.22.62]
107142678  Casp3; caspase-3 isoform X1 [KO:K02187] [EC:3.4.22.56]
107158031  caspase-3-like [KO:K02187] [EC:3.4.22.56]
107147046  Hip1; huntingtin-interacting protein 1 isoform X1 [KO:K04559]
107136338  Ift57; intraflagellar transport protein 57 homolog [KO:K04638]
107159874  Hsd17b10; 3-hydroxyacyl-CoA dehydrogenase type-2 [KO:K08683] [EC:1.1.1.35 1.1.1.178]
107141293  Ppid; peptidyl-prolyl cis-trans isomerase D [KO:K05864] [EC:5.2.1.8]
107154087  peptidyl-prolyl cis-trans isomerase D [KO:K05864] [EC:5.2.1.8]
107155537  Park7; Parkinson disease protein 7 isoform X1 [KO:K05687] [EC:3.5.1.124]
107143681  bcl-2-like protein 1 [KO:K04570]
107139077  Bcl2l1; bcl-2-like protein 1 isoform X1 [KO:K04570]
107142240  LOW QUALITY PROTEIN: bcl-2-like protein 1 [KO:K04570]
107153030  bcl-2-like protein 1 [KO:K04570]
107149462  Mfn1; mitofusin-1 [KO:K21356] [EC:3.6.5.-]
107155488  Mfn2; mitofusin-2 [KO:K06030] [EC:3.6.5.-]
107140452  Optn; optineurin isoform X1 [KO:K19946]
107159781  Sqstm1; sequestosome-1 isoform X1 [KO:K14381]
107151330  LOW QUALITY PROTEIN: microtubule-associated proteins 1A/1B light chain 3B-like [KO:K10435]
107140355  Map1lc3c; microtubule-associated proteins 1A/1B light chain 3C [KO:K10435]
107134511  Map1lc3a; microtubule-associated proteins 1A/1B light chain 3A [KO:K10435]
107151029  Map1lc3b; microtubule-associated proteins 1A/1B light chain 3B [KO:K10435]
107140093  Tbk1; serine/threonine-protein kinase TBK1 [KO:K05410] [EC:2.7.11.10]
107136882  Tank; TRAF family member-associated NF-kappa-B activator isoform X5 [KO:K12650]
107152302  Wdr41; WD repeat-containing protein 41 [KO:K23610]
107157191  Smcr8; guanine nucleotide exchange protein SMCR8 [KO:K23611]
107145041  Rab8a; ras-related protein Rab-8A [KO:K07901]
107160951  Rab39b; ras-related protein Rab-39B [KO:K07925]
107136983  Rab1a; LOW QUALITY PROTEIN: ras-related protein Rab-1A [KO:K07874]
107155502  Mtor; serine/threonine-protein kinase mTOR [KO:K07203] [EC:2.7.11.1]
107159067  Ulk1; serine/threonine-protein kinase ULK1 isoform X1 [KO:K21357] [EC:2.7.11.1]
107160172  Ulk2; serine/threonine-protein kinase ULK2 isoform X1 [KO:K08269] [EC:2.7.11.1]
107148648  Atg101; autophagy-related protein 101 [KO:K19730]
107135797  Atg13; autophagy-related protein 13 isoform X1 [KO:K08331]
107142384  Rb1cc1; RB1-inducible coiled-coil protein 1 isoform X1 [KO:K17589]
107135795  Ambra1; activating molecule in BECN1-regulated autophagy protein 1 isoform X1 [KO:K17985]
107150548  Becn1; beclin-1 isoform X1 [KO:K08334]
107140265  Becn2; beclin-2 [KO:K08334]
107143405  Pik3r4; phosphoinositide 3-kinase regulatory subunit 4 isoform X2 [KO:K08333] [EC:2.7.11.1]
107138297  Atg14; beclin 1-associated autophagy-related key regulator [KO:K17889]
107158234  Nrbf2; nuclear receptor-binding factor 2 isoform X1 [KO:K21246]
107139532  Pik3c3; LOW QUALITY PROTEIN: phosphatidylinositol 3-kinase catalytic subunit type 3 [KO:K00914] [EC:2.7.1.137]
107150385  Atg2b; autophagy-related protein 2 homolog B isoform X1 [KO:K17906]
107135989  Atg2a; autophagy-related protein 2 homolog A [KO:K17906]
107158368  Wipi1; WD repeat domain phosphoinositide-interacting protein 1 [KO:K17908]
107155980  Wipi2; WD repeat domain phosphoinositide-interacting protein 2 isoform X3 [KO:K17908]
107148832  Zfyve1; zinc finger FYVE domain-containing protein 1 [KO:K17603]
107138614  Als2; alsin isoform X1 [KO:K04575]
107149587  Rab5a; ras-related protein Rab-5A isoform X1 [KO:K07887]
107155970  Rac1; ras-related C3 botulinum toxin substrate 1 isoform X2 [KO:K04392]
107136394  Chmp2b; charged multivesicular body protein 2b [KO:K12192]
107154459  Fig4; polyphosphoinositide phosphatase isoform X1 [KO:K22913] [EC:3.1.3.-]
107137632  Spg11; spatacsin [KO:K19026]
107143715  Tnf; tumor necrosis factor [KO:K03156]
107154973  Tnfrsf1a; tumor necrosis factor receptor superfamily member 1A [KO:K03158]
107155486  Tnfrsf1b; tumor necrosis factor receptor superfamily member 1B [KO:K05141]
107143785  Daxx; death domain-associated protein 6 [KO:K02308]
107157178  dual specificity mitogen-activated protein kinase kinase 3 isoform X1 [KO:K04432] [EC:2.7.12.2]
107157181  Map2k6; dual specificity mitogen-activated protein kinase kinase 6 isoform X2 [KO:K04433] [EC:2.7.12.2]
107143838  Mapk14; mitogen-activated protein kinase 14 isoform X1 [KO:K04441] [EC:2.7.11.24]
107143841  Mapk13; mitogen-activated protein kinase 13 isoform X3 [KO:K04441] [EC:2.7.11.24]
107134469  mitogen-activated protein kinase 12 isoform X1 [KO:K04441] [EC:2.7.11.24]
107134485  mitogen-activated protein kinase 11 [KO:K04441] [EC:2.7.11.24]
107160230  mitogen-activated protein kinase 12-like isoform X1 [KO:K04441] [EC:2.7.11.24]
107156451  Nos1; LOW QUALITY PROTEIN: nitric oxide synthase, brain [KO:K13240] [EC:1.14.13.39]
107156986  Ccs; copper chaperone for superoxide dismutase [KO:K04569]
107143484  Gpx1; glutathione peroxidase 1 [KO:K00432] [EC:1.11.1.9]
107148105  Gpx3; glutathione peroxidase 3 [KO:K00432] [EC:1.11.1.9]
107141762  Gpx7; glutathione peroxidase 7 [KO:K00432] [EC:1.11.1.9]
107151887  Gpx8; probable glutathione peroxidase 8 isoform X2 [KO:K00432] [EC:1.11.1.9]
107160503  Gpx5; epididymal secretory glutathione peroxidase [KO:K00432] [EC:1.11.1.9]
107160504  Gpx6; glutathione peroxidase 6 [KO:K00432] [EC:1.11.1.9]
107146162  Gpx2; glutathione peroxidase 2 [KO:K00432] [EC:1.11.1.9]
107135748  Cat; catalase [KO:K03781] [EC:1.11.1.6]
107148602  Prph; peripherin isoform X1 [KO:K07607]
107153847  Nefl; neurofilament light polypeptide [KO:K04572]
107153848  Nefm; neurofilament medium polypeptide isoform X1 [KO:K04573]
107154504  Nefh; neurofilament heavy polypeptide isoform X1 [KO:K04574]
107140127  Kif5a; kinesin heavy chain isoform X2 [KO:K10396]
107140244  Kif5b; kinesin-1 heavy chain [KO:K10396]
107136617  Kif5c; LOW QUALITY PROTEIN: kinesin heavy chain [KO:K10396]
107151611  Klc3; kinesin light chain 3 [KO:K10407]
107143933  Klc4; kinesin light chain 4 isoform X1 [KO:K10407]
107150940  Klc1; kinesin light chain 1 isoform X1 [KO:K10407]
107156961  Klc2; kinesin light chain 2 isoform X1 [KO:K10407]
107138719  tubulin alpha-4A chain [KO:K07374]
107138722  tubulin alpha-1D chain isoform X1 [KO:K07374]
107134536  tubulin alpha-1B chain-like [KO:K07374]
107140681  tubulin alpha-8 chain isoform X1 [KO:K07374]
107141892  tubulin alpha-1C chain-like isoform X1 [KO:K07374]
107148600  Tuba1a; tubulin alpha-1A chain [KO:K07374]
107148601  tubulin alpha-1C chain [KO:K07374]
107150280  Tubal3; tubulin alpha chain-like 3 [KO:K07374]
107154571  tubulin alpha-8 chain-like [KO:K07374]
107154692  tubulin alpha-3 chain [KO:K07374]
107154696  tubulin alpha-3 chain [KO:K07374]
107155040  Tuba8; tubulin alpha-8 chain isoform X1 [KO:K07374]
107149203  Tubb2a; tubulin beta-2A chain [KO:K07375]
107149205  tubulin beta-2B chain [KO:K07375]
107137659  Tubb1; tubulin beta-1 chain isoform X1 [KO:K07375]
107150800  Tubb3; tubulin beta-3 chain [KO:K07375]
107134810  uncharacterized protein D806_0078-like [KO:K07375]
107159219  Tubb4b; tubulin beta-4B chain [KO:K07375]
107159459  tubulin beta-5 chain [KO:K07375]
107160457  Tubb; tubulin beta chain [KO:K07375]
107146111  tubulin beta chain-like [KO:K07375]
107146249  tubulin beta-2A chain-like isoform X1 [KO:K07375]
107157327  Tubb4a; tubulin beta-4A chain [KO:K07375]
107136282  Gsk3b; glycogen synthase kinase-3 beta isoform X1 [KO:K03083] [EC:2.7.11.26]
107144817  Csnk2a2; casein kinase II subunit alpha' [KO:K03097] [EC:2.7.11.1]
107139161  Csnk2a1; casein kinase II subunit alpha isoform X1 [KO:K03097] [EC:2.7.11.1]
107143723  Csnk2b; casein kinase II subunit beta isoform X2 [KO:K03115]
107134338  Bdnf; brain-derived neurotrophic factor isoform X1 [KO:K04355]
107154215  Dctn1; dynactin subunit 1 isoform X11 [KO:K04648]
107140131  Dctn2; dynactin subunit 2 isoform X3 [KO:K10424]
107147836  Dctn3; dynactin subunit 3 isoform X1 [KO:K10425]
107142840  Dctn4; dynactin subunit 4 isoform X2 [KO:K10426]
107146869  Dctn5; dynactin subunit 5 isoform X1 [KO:K10427]
107156464  dynactin subunit 6-like [KO:K10428]
107155357  Dctn6; dynactin subunit 6 isoform X1 [KO:K10428]
107149838  Actr1a; alpha-centractin [KO:K16575]
107154121  Actr1b; beta-centractin [KO:K16575]
107138311  Actr10; actin-related protein 10 isoform X1 [KO:K16576]
107150588  Hap1; huntingtin-associated protein 1 isoform X1 [KO:K04647]
107149705  Dnah1; dynein axonemal heavy chain 1 isoform X2 [KO:K10408]
107143624  Dnah8; dynein axonemal heavy chain 8 [KO:K10408]
107158049  Dnah9; dynein axonemal heavy chain 9 isoform X1 [KO:K10408]
107138353  Dnah7; dynein axonemal heavy chain 7 isoform X1 [KO:K10408]
107140282  Dnah14; dynein axonemal heavy chain 14 [KO:K10408]
107146320  Dnah5; dynein axonemal heavy chain 5 isoform X1 [KO:K10408]
107154254  Dnah6; dynein axonemal heavy chain 6 isoform X1 [KO:K10408]
107156340  Dnah10; dynein axonemal heavy chain 10 isoform X1 [KO:K10408]
107147153  Dnah3; dynein axonemal heavy chain 3 isoform X1 [KO:K10408]
107157847  Dnah17; dynein axonemal heavy chain 17 [KO:K10408]
107158008  Dnah2; dynein axonemal heavy chain 2 isoform X1 [KO:K10408]
107152632  Dnah11; dynein axonemal heavy chain 11 isoform X1 [KO:K10408]
107149695  Dnah12; dynein axonemal heavy chain 12 [KO:K10408]
107141508  Dnali1; axonemal dynein light intermediate polypeptide 1 [KO:K10410]
107147649  Dnai1; dynein axonemal intermediate chain 1 isoform X1 [KO:K10409]
107157219  Dnai2; dynein axonemal intermediate chain 2 isoform X2 [KO:K11143]
107148964  Dnal1; dynein axonemal light chain 1 [KO:K10411]
107139854  Dnal4; dynein axonemal light chain 4 [KO:K10412]
107141405  Camk2d; calcium/calmodulin-dependent protein kinase type II subunit delta isoform X9 [KO:K04515] [EC:2.7.11.17]
107142680  Camk2a; calcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1 [KO:K04515] [EC:2.7.11.17]
107146068  Camk2b; calcium/calmodulin-dependent protein kinase type II subunit beta isoform X1 [KO:K04515] [EC:2.7.11.17]
107158156  Camk2g; calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X1 [KO:K04515] [EC:2.7.11.17]
107136010  Capn1; calpain-1 catalytic subunit isoform X1 [KO:K01367] [EC:3.4.22.52]
107140516  Capn2; calpain-2 catalytic subunit [KO:K03853] [EC:3.4.22.53]
107155303  Cdk5r1; cyclin-dependent kinase 5 activator 1 [KO:K11716]
107148934  Cdk5; cyclin-dependent kinase 5 [KO:K02090] [EC:2.7.11.22]
107149904  Casp7; caspase-7 isoform X3 [KO:K04397] [EC:3.4.22.60]
107141168  Dkk2; dickkopf-related protein 2 [KO:K02165]
107159636  Dkk4; dickkopf-related protein 4 [KO:K02165]
107153348  Dkk1; dickkopf-related protein 1 [KO:K02165]
107148723  Wnt1; proto-oncogene Wnt-1 [KO:K03209]
107144491  Wnt2; protein Wnt-2 [KO:K00182]
107156150  Wnt2b; protein Wnt-2b [KO:K00182]
107160515  Wnt3; proto-oncogene Wnt-3 [KO:K00312]
107153302  Wnt3a; protein Wnt-3a [KO:K00312]
107142152  Wnt4; protein Wnt-4 [KO:K00408]
107149617  Wnt5a; LOW QUALITY PROTEIN: protein Wnt-5a [KO:K00444]
107155012  Wnt5b; protein Wnt-5b isoform X3 [KO:K00444]
107138480  Wnt6; protein Wnt-6 [KO:K00445]
107150185  protein Wnt-7a [KO:K00572]
107155744  Wnt7b; protein Wnt-7b [KO:K00572]
107141176  Wnt8a; protein Wnt-8a [KO:K00714]
107149946  Wnt8b; protein Wnt-8b [KO:K00714]
107160533  Wnt9b; protein Wnt-9b [KO:K01064]
107153234  Wnt9a; protein Wnt-9a isoform X1 [KO:K01064]
107138402  Wnt10a; protein Wnt-10a [KO:K01357]
107148595  Wnt10b; protein Wnt-10b isoform X1 [KO:K01357]
107135499  Wnt11; protein Wnt-11 isoform X1 [KO:K01384]
107144604  Wnt16; protein Wnt-16 [KO:K01558]
107138616  Fzd7; frizzled-7 [KO:K02432]
107156284  Fzd1; frizzled-1 [KO:K02432]
107150685  Fzd2; frizzled-2 [KO:K02235]
107153882  Fzd3; frizzled-3 [KO:K02329]
107156646  Fzd4; frizzled-4 [KO:K02354]
107140236  uncharacterized protein LOC107140236 [KO:K02375]
107142849  Fzd6; frizzled-6 isoform X1 [KO:K02376]
107147043  Fzd9; frizzled-9 [KO:K02842]
107159092  Fzd10; frizzled-10 [KO:K02842]
107152668  Lrp6; low-density lipoprotein receptor-related protein 6 isoform X1 [KO:K03068]
107157026  Lrp5; low-density lipoprotein receptor-related protein 5 isoform X2 [KO:K03068]
107139865  Csnk1e; casein kinase I isoform X1 [KO:K08960] [EC:2.7.11.1]
107155457  Dvl1; segment polarity protein dishevelled homolog DVL-1 [KO:K02353]
107154316  Dvl3; segment polarity protein dishevelled homolog DVL-3 [KO:K02353]
107157968  Dvl2; segment polarity protein dishevelled homolog DVL-2 isoform X1 [KO:K02353]
107149936  Frat1; LOW QUALITY PROTEIN: proto-oncogene FRAT1 [KO:K03069]
107149939  Frat2; GSK-3-binding protein FRAT2 [KO:K03096]
107146791  Axin1; axin-1 isoform X1 [KO:K02157]
107158361  Axin2; axin-2 isoform X1 [KO:K04385]
107141069  Apc; adenomatous polyposis coli protein isoform X6 [KO:K02085]
107157407  Apc2; LOW QUALITY PROTEIN: adenomatous polyposis coli protein 2 [KO:K02085]
107145471  Ctnnb1; catenin beta-1 [KO:K02105]
107142599  Csnk1a1; casein kinase I isoform X4 [KO:K08957] [EC:2.7.11.1]
107142608  casein kinase I-like [KO:K08957] [EC:2.7.11.1]
107143760  Ager; advanced glycosylation end product-specific receptor isoform X1 [KO:K19722]
107157108  Hras; GTPase HRas isoform X1 [KO:K02833]
107152729  Kras; GTPase KRas isoform X1 [KO:K07827]
107156178  Nras; GTPase NRas [KO:K07828]
107144326  Araf; serine/threonine-protein kinase A-Raf isoform X1 [KO:K08845] [EC:2.7.11.1]
107149118  Braf; serine/threonine-protein kinase B-raf isoform X7 [KO:K04365] [EC:2.7.11.1]
107150090  Raf1; RAF proto-oncogene serine/threonine-protein kinase isoform X2 [KO:K04366] [EC:2.7.11.1]
107138000  Map2k1; dual specificity mitogen-activated protein kinase kinase 1 isoform X1 [KO:K04368] [EC:2.7.12.2]
107157283  Map2k2; dual specificity mitogen-activated protein kinase kinase 2 [KO:K04369] [EC:2.7.12.2]
107146562  Mapk3; mitogen-activated protein kinase 3 [KO:K04371] [EC:2.7.11.24]
107154676  Mapk1; mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
107156226  Nox1; NADPH oxidase 1 [KO:K08008]
107144192  LOW QUALITY PROTEIN: cytochrome b-245 heavy chain [KO:K21421] [EC:1.-.-.-]
107135438  Nox4; NADPH oxidase 4 isoform X1 [KO:K21423] [EC:1.6.3.-]
107156942  Rela; transcription factor p65 [KO:K04735]
107141352  Nfkb1; nuclear factor NF-kappa-B p105 subunit isoform X1 [KO:K02580]
107155278  Nos2; nitric oxide synthase, inducible isoform X2 [KO:K13241] [EC:1.14.13.39]
107147540  Ptgs2; prostaglandin G/H synthase 2 [KO:K11987] [EC:1.14.99.1]
107146026  Il6; interleukin-6 [KO:K05405]
107154163  Il1a; interleukin-1 alpha [KO:K04383]
107154164  Il1b; interleukin-1 beta [KO:K04519]
107158610  Csf1; macrophage colony-stimulating factor 1 [KO:K05453]
Compound
C00001  H2O
C00002  ATP
C00008  ADP
C00009  Orthophosphate
C00012  Peptide
C00013  Diphosphate
C00017  Protein
C00020  AMP
C00025  L-Glutamate
C00027  Hydrogen peroxide
C00062  L-Arginine
C00070  Copper
C00076  Calcium cation
C00165  Diacylglycerol
C00533  Nitric oxide
C00704  Superoxide
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01330  Sodium cation
C01996  Acetylcholine
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C04599  1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
C07593  Rotenone
C11310  1-Methyl-4-phenylpyridinium
C15231  Maneb
C16514  Amyloid beta protein 40
C16515  Amyloid beta protein 42
C16844  Hydroxyl radical
C16845  Peroxynitrite
C21011  [Protein]-N(epsilon)-(carboxymethyl)lysine
C21012  [Protein]-N(epsilon)-(carboxyethyl)lysine
C21013  [Protein]-pyrraline
C21014  [Protein]-pentosidine
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Related
pathway
mmma00190  Oxidative phosphorylation
mmma03050  Proteasome
mmma04020  Calcium signaling pathway
mmma04120  Ubiquitin mediated proteolysis
mmma04137  Mitophagy - animal
mmma04140  Autophagy - animal
mmma04141  Protein processing in endoplasmic reticulum
mmma04142  Lysosome
mmma04210  Apoptosis
mmma04310  Wnt signaling pathway
mmma04724  Glutamatergic synapse
mmma04933  AGE-RAGE signaling pathway in diabetic complications
KO pathway
ko05022   
LinkDB

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