KEGG ORTHOLOGY: K13184

ORTHOLOGY: K13184

Entry

K13184                      KO

Symbol

DHX9

Name

ATP-dependent RNA/DNA helicase DHX9 [EC:5.6.2.6 5.6.2.4]

Disease

H00773

Autosomal dominant intellectual developmental disorder

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03041 Spliceosome
    K13184  DHX9; ATP-dependent RNA/DNA helicase DHX9
   03012 Translation factors
    K13184  DHX9; ATP-dependent RNA/DNA helicase DHX9
Enzymes [BR:ko01000]
5. Isomerases
  5.6  Isomerases altering macromolecular conformation
   5.6.2  Enzymes altering nucleic acid conformation
    5.6.2.4  DNA 3'-5' helicase
     K13184  DHX9; ATP-dependent RNA/DNA helicase DHX9
    5.6.2.6  RNA 3'-5' helicase
     K13184  DHX9; ATP-dependent RNA/DNA helicase DHX9
Spliceosome [BR:ko03041]
Other splicing related proteins
  Spliceosome associated proteins (SAPs)
   RNA helicase-like proteins
    K13184  DHX9; ATP-dependent RNA/DNA helicase DHX9
Translation factors [BR:ko03012]
Eukaryotic type
  Initiation factors
   Initiation associated factors
    K13184  DHX9; ATP-dependent RNA/DNA helicase DHX9

Other DBs

GO:	0033679 0034458 0043138

Genes

HSA:	1660(DHX9)

PTR:	457568(DHX9)

PPS:	100978418(DHX9)

GGO:	101125860(DHX9)

PON:	100449914(DHX9)

PPYG:

129016263(DHX9)

NLE:	100605661(DHX9)

HMH:	116458009(DHX9)

SSYN:

129458024(DHX9)

MCC:	715453(DHX9)

MCF:	102114768(DHX9)

MTHB:

126940300

MNI:	105484560(DHX9)

CSAB:

103230463(DHX9)

CATY:

105580344(DHX9)

PANU:

101011597(DHX9)

TGE:	112613082(DHX9)

MLEU:

105550419(DHX9)

RRO:	104666794(DHX9)

RBB:	108512716(DHX9)

TFN:	117076846(DHX9)

PTEH:

111536954(DHX9)

CANG:

105501959 105511895(DHX9)

CJC:	100403386(DHX9)

SBQ:	101043193(DHX9)

CIMI:

108301348(DHX9)

ANAN:

105711702(DHX9)

CSYR:

103276963(DHX9)

MMUR:

105855076(DHX9)

LCAT:

123627025(DHX9)

PCOQ:

105806789(DHX9)

OGA:	100953959(DHX9)

MMU:	13211(Dhx9)

MCAL:

110293208(Dhx9)

MPAH:

110322028(Dhx9)

RNO:	304859(Dhx9)

MCOC:

116101269(Dhx9)

ANU:	117716340(Dhx9)

ASYL:

127697188(Dhx9)

MUN:	110546188(Dhx9)

CGE:	100765632(Dhx9)

MAUA:

101831128(Dhx9)

PROB:

127223409(Dhx9)

PMAV:

102913082(Dhx9)

MORG:

121455375(Dhx9)

MFOT:

126497359

AAMP:

119827135(Dhx9)

NGI:	103739764 103745457

HGL:	101721209(Dhx9)

CPOC:

100726314(Dhx9)

CCAN:

109690267(Dhx9)

DORD:

105985243(Dhx9)

DSP:	122103668(Dhx9)

DMER:

138835771(Dhx9)

PLOP:

125359163(Dhx9)

NCAR:

124961973

MMMA:

107147315(Dhx9)

ITI:	101968295(Dhx9)

OCU:

100354085

OPI:

101519658

OCZ:	121159896(DHX9)

TUP:	102498283(DHX9)

GVR:	103610982(DHX9)

CFA:	480032(DHX9)

CLUD:

112648471(DHX9)

VVP:	112921806(DHX9)

VLG:	121494231(DHX9)

NPO:	129505938(DHX9)

AML:	100474564(DHX9)

UMR:	103672417(DHX9)

UAH:	113262730(DHX9)

UAR:	123801322(DHX9)

ELK:

111150713

LLV:

125085819

MPUF:

101683526(DHX9)

MNP:	132025445(DHX9)

MLK:	131815304(DHX9)

NVS:	122918604(DHX9)

ORO:	101383458(DHX9)

EJU:	114222836(DHX9)

ZCA:	113933062(DHX9)

MLX:	118014364(DHX9)

NSU:	110574112(DHX9)

LWW:	102749115(DHX9)

FCA:	101090831(DHX9)

PYU:	121011669(DHX9)

PCOO:

112857629(DHX9)

PBG:	122476227(DHX9)

PVIV:

125154998(DHX9)

LRUF:

124510145

LGF:	123584939(DHX9)

AJU:

106966731

PTG:	102965367(DHX9)

PPAD:

109253988(DHX9)

PUC:

125925787

PLEZ:

122211421(DHX9)

HHV:	120245833(DHX9)

BTA:	281115(DHX9)

BOM:	102271217(DHX9)

BIU:	109570443(DHX9)

BBUB:

102392694(DHX9)

BBIS:

104998087(DHX9)

CHX:	102169501(DHX9)

OAS:	101105091(DHX9)

BTAX:

128061189(DHX9)

CSUM:

138090415(DHX9)

ODA:	120880478(DHX9)

CCAD:

122451875(DHX9)

MREE:

136168553(DHX9)

OVR:	110140179(DHX9)

MBEZ:

129551307(DHX9)

SSC:	100514066(DHX9)

CFR:	102512094(DHX9)

CBAI:

105069028(DHX9)

CDK:	105096231(DHX9)

VPC:	102539843(DHX9)

BACU:

103004297(DHX9)

BMUS:

118894373(DHX9)

LVE:	103089502(DHX9)

OOR:	101281914(DHX9)

LALB:

132510175(DHX9)

GMF:	115848431(DHX9)

DDP:	132440094(DHX9)

DLE:	111184632(DHX9)

PCAD:

102981205(DHX9)

PSIU:

116756635(DHX9)

PPHC:

136120222(DHX9)

NASI:

112391150(DHX9)

ECB:	100055171(DHX9)

EPZ:	103551987(DHX9)

EAI:	106847449(DHX9)

MYB:	102240793(DHX9)

MYD:	102757745(DHX9)

MMYO:

118673645(DHX9)

MLF:	102437387(DHX9)

MDT:	132220417(DHX9)

MYUM:

138996295(DHX9)

PKL:	118721250(DHX9)

EFUS:

103290014(DHX9)

MNA:	107546276(DHX9)

DRO:	112297938(DHX9)

SHON:

118979226(DHX9)

AJM:	119049612(DHX9)

PDIC:

114511841(DHX9)

PHAS:

123818332(DHX9)

MMF:	118637071(DHX9)

PPAM:

129081989(DHX9)

HAI:	109379166(DHX9) 109390504

RFQ:	117014868(DHX9)

PALE:

102892574(DHX9)

PGIG:

120617581(DHX9)

PVP:	105292828(DHX9)

RAY:	107511290(DHX9)

MJV:	108401388(DHX9)

TOD:	119241201(DHX9)

SARA:

101548508(DHX9)

SFUM:

130017430(DHX9)

SETR:

126013354(DHX9)

LAV:	100661912(DHX9)

TMU:

101359794

ETF:	101651279(DHX9)

DNM:	101443151(DHX9)

MDO:	100018144(DHX9)

GAS:	123243715(DHX9)

SHR:	100918214(DHX9)

AFZ:

127562817

PCW:	110206840(DHX9)

TVP:	118846158(DHX9)

PBRV:

138150977(DHX9)

MLAO:

141512870(DHX9)

OAA:	100085716(DHX9)

TACU:

119938784(DHX9)

TGU:	100224822(DHX9)

LSR:	110467801(DHX9)

SCAN:

103814819(DHX9)

PMOA:

120510478(DHX9)

OTC:	121344600(DHX9)

PRUF:

121360086(DHX9)

ATRC:

139594209(DHX9)

GFR:	102043898(DHX9)

FAB:	101809675(DHX9)

OMA:	130255995(DHX9)

PHI:	102100700(DHX9)

PMAJ:

107207917(DHX9)

CCAE:

111932556(DHX9)

CCW:	104693623(DHX9)

CBRC:

103617141(DHX9)

ACOE:

138114395(DHX9)

ETL:	114061934(DHX9)

ZAB:	102074281(DHX9)

ZLE:	135450810(DHX9)

ACHL:

103810768(DHX9)

SVG:	106859444(DHX9)

MMEA:

130581545(DHX9)

HRT:	120756541(DHX9)

SATI:

136364672(DHX9)

CFAI:

136294481(DHX9)

CCIC:

134046494(DHX9)

FPG:	101917500(DHX9)

FCH:	102056504(DHX9)

CCRI:

104159234(DHX9)

NNT:	104406630(DHX9)

SHAB:

115612234(DHX9)

ACUN:

113482954(DHX9)

SURA:

141946751(DHX9)

TALA:

104357429(DHX9)

ACHC:

115349467(DHX9)

HALD:

104318637(DHX9)

HLE:	104840051(DHX9)

AGEN:

126041989

HHAR:

128148156(DHX9)

GCL:

127019311

CSTI:

104555566(DHX9)

LDI:	104339752(DHX9)

MNB:	103771031(DHX9)

DPUB:

104308021(DHX9)

PPUS:

135177711(DHX9)

AVIT:

104269277(DHX9)

BRHI:

104493655(DHX9)

EGZ:	118452687(DHX9)

NNI:	104011353(DHX9)

PCRI:

104030473(DHX9)

PCAO:

104052782(DHX9)

PADL:

103917508(DHX9)

AFOR:

103896124(DHX9)

FGA:	104081417(DHX9)

CBOR:

142085167(DHX9)

GSTE:

104263404(DHX9)

CBOY:

140654530(DHX9)

MAME:

142412494(DHX9)

CLV:	102093789(DHX9)

CNIC:

135996783(DHX9)

MUI:	104543307(DHX9)

PGUU:

104471003(DHX9)

PLET:

104617714(DHX9)

EHS:	104511442(DHX9)

CMAC:

104484948(DHX9)

CUCA:

104058597(DHX9)

TEO:	104373153(DHX9)

BREG:

104632171(DHX9)

GAME:

129209190(DHX9)

OHA:	104334021(DHX9)

ACAR:

104519982(DHX9)

CPEA:

104386145(DHX9)

CVF:	104293440(DHX9)

RTD:	128913501(DHX9)

CRID:

134519156(DHX9)

LMIC:

141747258(DHX9)

AAM:	106495747(DHX9)

AROW:

112964308(DHX9)

NPD:	112951537(DHX9)

TGT:	104566579(DHX9)

DNE:	112983719(DHX9)

SCAM:

104142714(DHX9)

ASN:	102368130(DHX9)

AMJ:	102560403(DHX9)

CPOO:

109307194(DHX9)

GGN:	109286936(DHX9)

PSS:	102462609(DHX9)

CIZ:	142017482(DHX9)

CMY:	102943778(DHX9)

CCAY:

125641014(DHX9)

LKP:	140915943(DHX9)

DCC:	119860062(DHX9)

CPIC:

101937344(DHX9)

TST:	117881373(DHX9)

CABI:

116824278(DHX9)

MRV:	120370169(DHX9) 120394265

ACS:	100559537(dhx9)

ASAO:

132774396(DHX9)

PVT:	110077050(DHX9)

SUND:

121928876(DHX9)

PBI:	103052673(DHX9)

PMUR:

107284978(DHX9)

CTIG:

120314960(DHX9)

TSR:	106542744(DHX9)

PGUT:

117661124(DHX9)

PCAE:

139314934(DHX9)

APRI:

131195944(DHX9)

PTEX:

113438071(DHX9)

NSS:	113413173(DHX9)

VKO:	123027875(DHX9)

PMUA:

114598506(DHX9)

PRAF:

128415197(DHX9)

ZVI:	118088549(DHX9)

HCG:	128323909(DHX9)

GJA:	107121030(DHX9)

STOW:

125425029(DHX9)

EMC:	129330067(DHX9)

XLA:	108715635 447207(dhx9.L)

XTR:	733723(dhx9)

NPR:	108803295(DHX9)

RTEM:

120945826(DHX9)

ACAT:

141103594(DHX9)

PADS:

140336572(DHX9)

BBUF:

120978612(DHX9)

BGAR:

122943399(DHX9)

DTC:	141085773(DHX9)

PWL:	138293059(DHX9)

MUO:	115471684(DHX9)

GSH:	117346497(DHX9)

DRE:	568043(dhx9)

SRX:	107722046 107726925(dhx9)

SANH:

107658362(dhx9)

SGH:	107563559(dhx9)

CCAR:

109059012 109108367

CAUA:

113045435 113119096

CGIB:

127951241 128030998

PTET:

122325004(dhx9)

LROH:

127178040(dhx9)

GRF:	141343093(dhx9)

OMC:	131531303(dhx9)

PPRM:

120465098(dhx9)

RKG:	130071570(dhx9)

MAMB:

125250657(dhx9)

CIDE:

127505216

CERY:

137003419(dhx9)

MASI:

127441378 127442215

TROS:

130554983(dhx9)

TDW:	130418278(dhx9)

MANU:

129441989(dhx9)

PDAB:

135767042(dhx9)

IPU:

108267335

IFU:	128609470(dhx9)

PHYP:

113540379(dhx9)

SMEO:

124387779(dhx9)

TFD:	113644111(dhx9)

TVC:	132848317(dhx9)

CGAR:

128530316(dhx9)

NGRA:

132892684(dhx9)

TRN:	134312192(dhx9)

AMEX:

103039545(dhx9)

CMAO:

118825672(dhx9)

EEE:	113578222(dhx9)

CHAR:

105898736(dhx9)

SPIL:

134071153(dhx9)

ASAD:

121718804(dhx9)

TRU:	101061920(dhx9)

TFS:	130538361(dhx9)

TNG:	GSTEN00003947G001 GSTEN00007419G001

LCO:	104937397(dhx9)

TBEN:

117498836

PGEO:

117443363(dhx9)

EMAC:

134866009(dhx9)

ELY:	117271972(dhx9)

EFO:	125902867(dhx9)

PLEP:

121951150(dhx9)

SLUC:

116056371(dhx9)

PFLV:

114566054(dhx9)

PPUG:

119208999(dhx9)

AFB:	129113256(dhx9)

CLUM:

117746422(dhx9)

PSWI:

130190888(dhx9)

CANA:

137779542(dhx9)

CVE:	137884327(dhx9)

MSAM:

119902727 119902728(dhx9)

SCHU:

122886827(dhx9)

CUD:	121520344(dhx9)

SPUL:

138611656(dhx9)

LMIX:

132979588(dhx9)

HTC:	141803948(dhx9)

ALAT:

119010639(dhx9)

ASTR:

137612898(dhx9)

MZE:	101477935(dhx9)

ONL:	100697569(dhx9)

OAU:	116314199(dhx9)

OLA:	101156199(dhx9)

OML:	112144396(dhx9)

CSAI:

133452151(dhx9)

XMA:	102220466(dhx9)

XCO:	114145973(dhx9)

XHE:	116720922(dhx9)

PRET:

103479954(dhx9)

PFOR:

103156146(dhx9)

PLAI:

106961305(dhx9)

PMEI:

106923904(dhx9)

GAF:	122841661(dhx9)

PPRL:

129352680(dhx9)

CVG:	107102515(dhx9)

CTUL:

119773161(dhx9)

GMU:	124870154 124870468(dhx9)

NFU:	107383679(dhx9)

KMR:	108228505(dhx9)

ALIM:

106531542(dhx9)

NWH:	119415274(dhx9)

AOCE:

111571295(dhx9)

EJA:	138210855(dhx9)

BFRE:

138635401(dhx9)

MCEP:

125010887(dhx9)

CSEM:

103398898(dhx9)

POV:

109645768

SSEN:

122769156(dhx9)

SSOE:

131463809(dhx9)

HHIP:

117778603(dhx9)

HSP:	118117819(dhx9)

PPLT:

128454398(dhx9)

SMAU:

118310324(dhx9)

LCF:

108884873

SDU:	111231763(dhx9)

SLAL:

111649848(dhx9)

XGL:	120800178(dhx9)

HCQ:	109518912(dhx9)

SSCV:

125985445(dhx9)

SBIA:

133510652(dhx9)

PEE:	133411291(dhx9)

PTAO:

133488732(dhx9)

BPEC:

110166492(dhx9)

ENY:	140355882(dhx9)

MALB:

109973975(dhx9)

BSPL:

114844117(dhx9)

SJO:	128368627(dhx9)

SSCO:

133977159(dhx9)

TTY:	137194793(dhx9)

GMH:	115548556(dhx9)

SASA:

106569111 106599428(dhx9)

STRU:

115169789(dhx9)

OTW:

112226963

OMY:	110508753(dhx9)

OGO:

124041881

ONE:	115103108(dhx9)

OKI:	109871641(dhx9)

OKE:	118394629(dhx9)

OMM:

135558678

OCLA:

139376062

SALP:

111956997 111979152(dhx9)

SNH:	120020373(dhx9) 120055562

SFON:

129824006(dhx9)

CCLU:

121580901

ELS:	105018131(dhx9)

OEP:	134036330(dhx9)

SFM:	108935240(dhx9)

PKI:	111838960(dhx9)

AANG:

118230751(dhx9)

AROT:

135256519(dhx9)

CCOG:

133129549(dhx9)

LOC:	102694228(dhx9)

PSPA:

121326942(dhx9)

ARUT:

117411153 117417314(dhx9)

PSEX:

120514238(dhx9)

LCM:	102363284(DHX9)

CMK:	103179991(dhx9)

RTP:	109935354(dhx9)

CPLA:

122554463(dhx9)

CPUN:

140479666(dhx9)

HOC:	132819036(dhx9)

SCAU:

119964222(dhx9)

LERI:

129701135(dhx9)

HAKA:

140737106(dhx9)

PMRN:

116958233(DHX9)

BFO:

BBEL:

CIN:

SCLV:

SPU:

LVG:

AJJ:

APLC:

ARUN:

AAMU:

AFIL:

AJC:

SKO:

PFLL:

DME:	Dmel_CG11680(mle)

DER:

6542908

DSE:

6619142

DSI:	Dsimw501_GD10344(Dsim_GD10344)

DYA:	Dyak_GE19435

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI19596

DAZ:

108616832

DNV:

108654219

DHE:

111603406

DVI:	6635863(mle)

CCAT:

BOD:

BDR:

RZE:

AOQ:

ALUD:

TDA:

MDE:

SCAC:

LCQ:

LSQ:

CVJ:	135954687(mle)

GFS:	119643076 119645233

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AMAP:

AFUN:

AMOU:

AMRS:

AALI:

ADAR:

ACOS:

AAG:

AALB:

ASUA:

CPII:

CBRI:

CNS:

BCOO:

LLL:

PPAP:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BHUN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

ACOC:

MZT:	108723608(mle)

CCOA:

TCZ:

TSEP:

PBAR:

VEM:

COBS:

139108525(Mle)

TLN:	139810382(Mle)

HST:

DQU:

CFO:

FEX:

PMEC:

138936023(Mle)

LHU:	105674126(mle)

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:	122498541 122505505

LBD:	127285885 127288303

MDL:

103575106

CGLO:

123267389

CTYP:

141527863(Mle)

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

DSM:

NPT:	124212855(mle)

NFB:

NLO:

NVG:

AROA:

TCA:

TMOL:

138139995(mle)

DPA:

109535712

ESIM:

136416546(mle)

EFOR:

136343935(mle)

SOY:

115879845

RFG:	143199030(mle)

AGRG:

ATD:

CSET:

HAXR:

AGB:	108910818 108913786

LDC:

DVV:

NVL:

APLN:

PPYR:

OTU:

BMOR:

100101216(MLE)

BMAN:

114247315

MSEX:

115442824

DPL:	KGM_206766

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

BPHI:

137926089(mle)

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:	113494800 113506242

SLIU:

111357090

OFU:	114361915 114363460

ONU:

ATRA:

GMW:

PGW:

LGLY:

CSTB:

CFUM:

141442502(mle)

CFEL:

113364189

CCRN:

123295354

API:	100160936 100161984 100162500

DNX:	107167339 107170739

AGS:	114123995 114133120

RMD:	113552689 113557401 113559265

ACOO:

126835468 126836272 126837860

DVT:	126894756 126900538

BTAB:

109037862

DCI:

103505705

CLEC:

106661902

HHAL:

106683885(mle)

NLU:	111043256 111063275

LDA:	142323964(mle)

HVI:

124362103

MQU:	128993822 128993827

PHU:	Phum_PHUM607970

FOC:

TPAL:

ZNE:

CSEC:

PAME:

138712559(mle)

SGRE:

126365821

BROR:

134540891

IEL:

124154148

HAMR:

139690340(mle)

FCD:

110842998

DPX:	DAPPUDRAFT_347560(MLE)

DMK:

116930319

DPZ:

124349338

AFRA:

136030870

PVM:	113802200(mle)

PJA:

PCHN:

PMOO:

HAME:

PCLA:

123769469(mle)

CQD:	128699963(mle) 128699969

PTRU:

123519470

ESN:

126981818

MNZ:

135222312

MRJ:	136841834 136841835

PORN:

139758047(mle)

HAZT:

108674879

OOT:	143027726(mle)

EAF:

111710977

LSM:	121114701(mle)

TCF:

PPOI:

ISC:

DSV:

DALB:

135896228(mle)

RSAN:

RMP:

VDE:

VJA:

TUT:

DPTE:

DFR:

CSCU:

CVS:	136978960(mle)

PTEP:

ABRU:

UDV:

SDM:

LPOL:

CEL:	CELE_T07D4.3(rha-1)

CBR:	CBG_03202(Cbr-rha-1)

CRQ:	GCK72_005620

HRO:	HELRODRAFT_64508

LGI:	LOTGIDRAFT_116243

PVUL:

PCAN:

LSAX:

BARL:

BGT:

GAE:

HRF:

HRJ:

HASI:

HCRA:

CRG:

CANU:

CVN:

OED:

PMAX:

AIRR:

YBA:

MCAF:

MMER:

RPHI:

DPOL:

OBI:

OSN:

LJP:

LAK:

SMM:	Smp_035030

SHX:	MS3_00005873(DHX9_2)

OVI:	T265_09022

EGL:

LLON:

NVE:

EPA:

ATEN:

ADF:	107327845 107353748

AMIL:

MCAZ:

MFOO:

PDAM:

SPIS:

DGT:

XEN:

HMG:

HSY:

RES:

TAD:	TRIADDRAFT_20896

PFP:	PFL1_04663

MSYM:

MSY001_2136

» show all

Reference

PMID:19229320

Authors

Sadler AJ, Latchoumanin O, Hawkes D, Mak J, Williams BR

Title

An antiviral response directed by PKR phosphorylation of the RNA helicase A.

Journal

PLoS Pathog 5:e1000311 (2009)
DOI:10.1371/journal.ppat.1000311

Sequence

[hsa:1660]

Reference

PMID:9111062

Authors

Zhang S, Grosse F

Title

Domain structure of human nuclear DNA helicase II (RNA helicase A).

Journal

J Biol Chem 272:11487-94 (1997)
DOI:10.1074/jbc.272.17.11487

LinkDB

DBGET integrated database retrieval system