KEGG   PATHWAY: lroh04810
Entry
lroh04810                   Pathway                                
Name
Regulation of actin cytoskeleton - Labeo rohita (rohu)
Class
Cellular Processes; Cell motility
Pathway map
lroh04810  Regulation of actin cytoskeleton
lroh04810

Other DBs
GO: 0030036
Organism
Labeo rohita (rohu) [GN:lroh]
Gene
127172286  lpar1; lysophosphatidic acid receptor 1 [KO:K04289]
127163985  lpar2b; lysophosphatidic acid receptor 2b isoform X1 [KO:K04291]
127163222  lpar2a; lysophosphatidic acid receptor 2a [KO:K04291]
127159146  lpar4; lysophosphatidic acid receptor 4 [KO:K04275]
127153474  cxcl12b; chemokine (C-X-C motif) ligand 12b (stromal cell-derived factor 1) [KO:K10031]
127174727  cxcl12a; chemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1) [KO:K10031]
127171224  cxcr4b; C-X-C chemokine receptor type 4b [KO:K04189]
127166295  cxcr4a; C-X-C chemokine receptor type 4a [KO:K04189]
127168348  f2; prothrombin [KO:K01313] [EC:3.4.21.5]
127164683  f2r; proteinase-activated receptor 1 [KO:K03914]
127151989  proteinase-activated receptor 1-like isoform X1 [KO:K03914]
127151993  proteinase-activated receptor 1-like [KO:K03914]
127151994  proteinase-activated receptor 1-like [KO:K03914]
127151996  proteinase-activated receptor 1-like isoform X1 [KO:K03914]
127152188  proteinase-activated receptor 1-like [KO:K03914]
127152190  proteinase-activated receptor 1-like [KO:K03914]
127152191  proteinase-activated receptor 1-like [KO:K03914]
127152192  proteinase-activated receptor 1-like [KO:K03914]
127152193  proteinase-activated receptor 1-like [KO:K03914]
127163542  insulin [KO:K04526]
127176089  insb; preproinsulin b [KO:K04526]
127164980  ins; insulin [KO:K04526]
127175864  egf; pro-epidermal growth factor [KO:K04357]
127176456  fgf1a; putative fibroblast growth factor 1 [KO:K18496]
127152732  fgf1b; fibroblast growth factor 1b [KO:K18496]
127176164  fgf2; fibroblast growth factor 2 [KO:K18497]
127175796  fgf24; fibroblast growth factor 24 isoform X1 [KO:K04358]
127175978  fgf18a; fibroblast growth factor 18a isoform X1 [KO:K04358]
127153769  fgf22; fibroblast growth factor 22 [KO:K04358]
127176067  fgf20b; fibroblast growth factor 20b [KO:K04358]
127164486  fgf6b; fibroblast growth factor 6b [KO:K04358]
127176482  fgf16; fibroblast growth factor 16 [KO:K04358]
127164903  fgf5; fibroblast growth factor 5 [KO:K04358]
127165580  fgf10b; fibroblast growth factor 10b [KO:K04358]
127171948  fgf8b; fibroblast growth factor 8b isoform X1 [KO:K04358]
127156481  fgf6a; fibroblast growth factor 6a [KO:K04358]
127172475  fgf18b; fibroblast growth factor 18b [KO:K04358]
127157456  fgf7; fibroblast growth factor 7 [KO:K04358]
127168077  fgf20a; fibroblast growth factor 20a [KO:K04358]
127168485  fgf4; fibroblast growth factor 4 [KO:K04358]
127152264  fgf10a; fibroblast growth factor 10a [KO:K04358]
127168576  fgf3; fibroblast growth factor 3 [KO:K04358]
127174689  fgf8a; LOW QUALITY PROTEIN: fibroblast growth factor 8 [KO:K04358]
127169363  fgf17; fibroblast growth factor 17 isoform X1 [KO:K04358]
127167790  fgf19; fibroblast growth factor 19 [KO:K22603]
127163180  fgf21; fibroblast growth factor 21 [KO:K22429]
127164405  fgf23; fibroblast growth factor 23 [KO:K22428]
127156480  uncharacterized protein LOC127156480 [KO:K22428]
127162991  pdgfbb; uncharacterized protein pdgfbb [KO:K04359]
127153154  pdgfaa; platelet-derived growth factor alpha polypeptide a isoform X1 [KO:K04359]
127163317  pdgfab; platelet-derived growth factor alpha polypeptide b isoform X1 [KO:K04359]
127153680  si:ch211-79m20.1; uncharacterized protein si:ch211-79m20.1 [KO:K17386]
127176608  pdgfc; platelet-derived growth factor C [KO:K05450]
127177739  pdgfd; platelet-derived growth factor D isoform X1 [KO:K05450]
127176285  egfra; epidermal growth factor receptor [KO:K04361] [EC:2.7.10.1]
127156110  epidermal growth factor receptor [KO:K04361] [EC:2.7.10.1]
127172252  fgfr1b; LOW QUALITY PROTEIN: fibroblast growth factor receptor 1b [KO:K04362] [EC:2.7.10.1]
127169481  fgfr1a; fibroblast growth factor receptor 1-A isoform X1 [KO:K04362] [EC:2.7.10.1]
127175355  fgfr2; fibroblast growth factor receptor 2 isoform X1 [KO:K05093] [EC:2.7.10.1]
127175122  fgfr3; LOW QUALITY PROTEIN: fibroblast growth factor receptor 3 [KO:K05094] [EC:2.7.10.1]
127152664  fgfr4; fibroblast growth factor receptor 4 [KO:K05095] [EC:2.7.10.1]
127183147  pdgfra; platelet-derived growth factor receptor alpha [KO:K04363] [EC:2.7.10.1]
127176102  pdgfrb; platelet-derived growth factor receptor beta [KO:K05089] [EC:2.7.10.1]
127170881  fn1a; LOW QUALITY PROTEIN: fibronectin 1a [KO:K05717]
127160000  itga1; integrin alpha-1 [KO:K06480]
127172447  itga2.2; integrin alpha-2 [KO:K06481]
127155505  itga2b; integrin alpha-IIb [KO:K06476]
127173940  itga3b; integrin alpha-3b isoform X1 [KO:K06482]
127163042  itga3a; integrin alpha-3 [KO:K06482]
127170405  itga4; integrin alpha-4 [KO:K06483]
127154577  itga5; integrin alpha-5 [KO:K06484]
127170731  itga6a; integrin alpha-6 isoform X1 [KO:K06485]
127176579  itga6l; LOW QUALITY PROTEIN: integrin alpha-6 [KO:K06485]
127168635  itga6b; integrin alpha-6b [KO:K06485]
127173364  itga7; integrin alpha-7 isoform X1 [KO:K06583]
127178218  itga8; integrin alpha-8 [KO:K06584]
127175258  itga9; integrin alpha-9 [KO:K06585]
127178896  itga10; integrin alpha-10 [KO:K06586]
127157132  itga11b; integrin alpha-11 [KO:K06587]
127169002  itga11a; LOW QUALITY PROTEIN: integrin alpha-11a [KO:K06587]
127170570  itgav; integrin alpha-V [KO:K06487]
127170715  integrin alpha-L-like isoform X1 [KO:K05718]
127170786  zmp:0000001082; LOW QUALITY PROTEIN: integrin alpha-D [KO:K05718]
127158770  integrin alpha-L [KO:K05718]
127161238  integrin alpha-L-like [KO:K05718]
127173805  LOW QUALITY PROTEIN: integrin alpha-X-like [KO:K06461]
127160516  LOW QUALITY PROTEIN: integrin alpha-M-like [KO:K06461]
127159242  integrin alpha-X-like isoform X1 [KO:K06462]
127173648  integrin alpha-X [KO:K06462]
127176995  itgae.2; LOW QUALITY PROTEIN: integrin alpha-E [KO:K06524]
127175891  integrin beta-1 isoform X1 [KO:K05719]
127155652  itgb1a; integrin beta-1a isoform X1 [KO:K05719]
127170701  itgb2; LOW QUALITY PROTEIN: integrin beta-2 [KO:K06464]
127173872  itgb3b; LOW QUALITY PROTEIN: integrin beta-3b [KO:K06493]
127163361  itgb3a; integrin beta-3a [KO:K06493]
127169510  itgb4; integrin beta-4 isoform X1 [KO:K06525]
127170828  itgb5; integrin beta-5 [KO:K06588]
127173525  itgb6; integrin beta-6 [KO:K06589]
127167365  itgb7; LOW QUALITY PROTEIN: integrin beta-7 [KO:K06590]
127182080  itgb8; integrin beta-8 isoform X1 [KO:K06591]
127153892  kng1; kininogen-1 [KO:K03898]
127179759  bdkrb1; B1 bradykinin receptor [KO:K03916]
127179760  bdkrb2; B2 bradykinin receptor [KO:K03916]
127183370  si:dkey-63b1.1; B2 bradykinin receptor [KO:K03916]
127175822  chrm1a; muscarinic acetylcholine receptor M1 [KO:K04129]
127164971  chrm1b; muscarinic acetylcholine receptor M1 [KO:K04129]
127164446  chrm2a; muscarinic acetylcholine receptor M2a [KO:K04130]
127157024  chrm2b; muscarinic acetylcholine receptor M2 [KO:K04130]
127180206  chrm3a; muscarinic acetylcholine receptor M3 [KO:K04131]
127174619  chrm3b; muscarinic acetylcholine receptor M3 [KO:K04131]
127156396  chrm4b; muscarinic acetylcholine receptor M4 [KO:K04132]
127168231  chrm4a; muscarinic acetylcholine receptor M4 [KO:K04132]
127180109  chrm5a; muscarinic acetylcholine receptor M5a [KO:K04133]
127183503  chrm5b; muscarinic acetylcholine receptor M5b [KO:K04133]
127165210  c5; complement C5 [KO:K03994]
127152155  c6; complement component C6 [KO:K03995]
127152341  c7b; complement component 7b [KO:K03996]
127169644  c7a; complement component C7 [KO:K03996]
127176063  c8a; complement component C8 alpha chain [KO:K03997]
127176073  complement component C8 beta chain isoform X1 [KO:K03998]
127155593  c8g; complement component C8 gamma chain [KO:K03999]
127165780  c9; complement component C9 [KO:K04000]
127160470  gna12a; guanine nucleotide-binding protein subunit alpha-12a [KO:K04346]
127158773  gna13b; guanine nucleotide-binding protein subunit alpha-13b [KO:K04639]
127174542  gna13a; guanine nucleotide-binding protein subunit alpha-13a [KO:K04639]
127166739  gng12b; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 [KO:K04347]
127152626  gng12a; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12a [KO:K04347]
127169559  fgd1; LOW QUALITY PROTEIN: FYVE, RhoGEF and PH domain-containing protein 1 [KO:K05720]
127170022  fgd; faciogenital dysplasia isoform X1 [KO:K05722]
127178815  ptk2ab; focal adhesion kinase 1 isoform X1 [KO:K05725] [EC:2.7.10.2]
127181451  ptk2aa; protein tyrosine kinase 2aa isoform X1 [KO:K05725] [EC:2.7.10.2]
127180490  bcar1; LOW QUALITY PROTEIN: breast cancer anti-estrogen resistance protein 1 [KO:K05726]
127177264  crk; adapter molecule crk [KO:K04438]
127152559  crkl; crk-like protein [KO:K04438]
127173764  dock1; dedicator of cytokinesis protein 1 isoform X1 [KO:K13708]
127154786  src; proto-oncogene tyrosine-protein kinase Src isoform X1 [KO:K05704] [EC:2.7.10.2]
127172877  sos1; LOW QUALITY PROTEIN: son of sevenless homolog 1 [KO:K03099]
127174997  sos2; son of sevenless homolog 2 [KO:K03099]
127156808  hrasa; HRas proto-oncogene, GTPase a [KO:K02833]
127168650  hrasb; HRas proto-oncogene, GTPase b [KO:K02833]
127156990  kras; GTPase KRas isoform X1 [KO:K07827]
127160738  zgc:55558; GTPase KRas [KO:K07827]
127169998  nras; GTPase NRas [KO:K07828]
127163541  rras; ras-related protein R-Ras [KO:K07830]
127168689  rras2; ras-related protein R-Ras2 [KO:K07830]
127153332  mrasb; ras-related protein M-Ras [KO:K07831]
127170844  mrasa; ras-related protein M-Ras [KO:K07831]
127175802  arhgef6; rho guanine nucleotide exchange factor 6 isoform X1 [KO:K05729]
127154480  pik3cd; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform [KO:K00922] [EC:2.7.1.153]
127177108  pik3cb; LOW QUALITY PROTEIN: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
127172737  pik3ca; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
127162255  zgc:158659; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
127176088  pik3r2; phosphatidylinositol 3-kinase regulatory subunit beta [KO:K02649]
127164849  pik3r1; LOW QUALITY PROTEIN: phosphatidylinositol 3-kinase regulatory subunit alpha [KO:K02649]
127166520  pik3r3b; phosphoinositide-3-kinase, regulatory subunit 3b (gamma) isoform X1 [KO:K02649]
127164113  proto-oncogene vav-like isoform X1 [KO:K05730]
127155509  guanine nucleotide exchange factor VAV3 isoform X1 [KO:K05730]
127179977  vav3b; guanine nucleotide exchange factor VAV3b isoform X1 [KO:K05730]
127153056  vav2; guanine nucleotide exchange factor VAV2 isoform X1 [KO:K05730]
127172545  tiam1a; rho guanine nucleotide exchange factor TIAM1 [KO:K05731]
127165632  araf; serine/threonine-protein kinase A-Raf [KO:K08845] [EC:2.7.11.1]
127163979  braf; serine/threonine-protein kinase B-raf isoform X1 [KO:K04365] [EC:2.7.11.1]
127154571  raf1a; raf-1 proto-oncogene, serine/threonine kinase a isoform X1 [KO:K04366] [EC:2.7.11.1]
127172884  raf1b; RAF proto-oncogene serine/threonine-protein kinase [KO:K04366] [EC:2.7.11.1]
127177092  mos; proto-oncogene serine/threonine-protein kinase mos [KO:K04367] [EC:2.7.11.1]
127180735  map2k1; LOW QUALITY PROTEIN: dual specificity mitogen-activated protein kinase kinase 1 [KO:K04368] [EC:2.7.12.2]
127153291  map2k2b; dual specificity mitogen-activated protein kinase kinase 2b [KO:K04369] [EC:2.7.12.2]
127153476  map2k2a; dual specificity mitogen-activated protein kinase kinase 2a [KO:K04369] [EC:2.7.12.2]
127164820  mapk1; mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
127162808  mapk3; mitogen-activated protein kinase 3 [KO:K04371] [EC:2.7.11.24]
127171830  akt2l; v-akt murine thymoma viral oncogene homolog 2, like [KO:K04456] [EC:2.7.11.1]
127168081  akt3b; RAC-gamma serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
127179883  akt1; RAC-alpha serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
127151836  RAC-alpha serine/threonine-protein kinase-like [KO:K04456] [EC:2.7.11.1]
127180526  akt2; RAC-beta serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
127174741  akt3a; RAC-gamma serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
127176043  si:dkey-27i16.2; regulator of cell cycle RGCC-like [KO:K26108]
127170982  rgcc; regulator of cell cycle RGCC [KO:K26108]
127177982  arhgef1b; rho guanine nucleotide exchange factor 1b isoform X1 [KO:K12330]
127165067  arhgef12b; rho guanine nucleotide exchange factor 12 isoform X1 [KO:K07532]
127177304  arhgef12a; LOW QUALITY PROTEIN: rho guanine nucleotide exchange factor 12 [KO:K07532]
127164967  arhgap35b; rho GTPase-activating protein 35 [KO:K05732]
127177429  arhgap35a; rho GTPase-activating protein 35 isoform X1 [KO:K05732]
127154872  rhoac; rho-related GTP-binding protein RhoA-C [KO:K04513]
127166810  rhoca; ras homolog family member Ca [KO:K04513]
127157396  rho-related GTP-binding protein RhoA-B-like isoform X1 [KO:K04513]
127169411  rhoaa; rho-related GTP-binding protein RhoA-A [KO:K04513]
127169606  rhoab; rho-related GTP-binding protein RhoA-B [KO:K04513]
127164254  ras-related C3 botulinum toxin substrate 1 [KO:K04392]
127178200  ras-related C3 botulinum toxin substrate 1-like [KO:K04392]
127158366  ras-related C3 botulinum toxin substrate 1 [KO:K04392]
127174083  rac1a; ras-related C3 botulinum toxin substrate 1 [KO:K04392]
127168243  ras-related C3 botulinum toxin substrate 1-like [KO:K04392]
127162984  rac1b; ras-related C3 botulinum toxin substrate 1b [KO:K04392]
127163181  rac2; ras-related C3 botulinum toxin substrate 2 [KO:K07860]
127174070  rac3b; ras-related C3 botulinum toxin substrate 3b [KO:K07861]
127163279  rac3a; ras-related C3 botulinum toxin substrate 3a [KO:K07861]
127154286  cdc42l2; cell division cycle 42 like 2 [KO:K04393]
127178154  cdc42l; cell division cycle 42, like [KO:K04393]
127173196  cdc42; cell division control protein 42 homolog isoform X1 [KO:K04393]
127180889  pak1; serine/threonine-protein kinase PAK 1 [KO:K04409] [EC:2.7.11.1]
127153773  pak2b; serine/threonine-protein kinase PAK 2b isoform X1 [KO:K04410] [EC:2.7.11.1]
127178121  pak2a; serine/threonine-protein kinase PAK 2a [KO:K04410] [EC:2.7.11.1]
127162623  serine/threonine-protein kinase PAK 3 isoform X1 [KO:K05733] [EC:2.7.11.1]
127176800  pak4; serine/threonine-protein kinase PAK 4 [KO:K05734] [EC:2.7.11.1]
127183356  pak5; serine/threonine-protein kinase PAK 5 isoform X1 [KO:K05736] [EC:2.7.11.1]
127179937  serine/threonine-protein kinase PAK 6 [KO:K05735] [EC:2.7.11.1]
127182619  pak6b; serine/threonine-protein kinase PAK 6b [KO:K05735] [EC:2.7.11.1]
127171155  arhgef7a; rho guanine nucleotide exchange factor 7a isoform X1 [KO:K13710]
127168093  arhgef7b; rho guanine nucleotide exchange factor 7b isoform X1 [KO:K13710]
127177099  git1; ARF GTPase-activating protein GIT1 isoform X1 [KO:K05737]
127175390  rock1; rho-associated protein kinase 1 isoform X1 [KO:K04514] [EC:2.7.11.1]
127175639  rock2a; rho-associated protein kinase 2 isoform X1 [KO:K17388] [EC:2.7.11.1]
127183479  rock2b; rho-associated protein kinase 2b isoform X1 [KO:K17388] [EC:2.7.11.1]
127155714  LOW QUALITY PROTEIN: myosin light chain kinase, smooth muscle-like [KO:K00907] [EC:2.7.11.18]
127170918  mylka; myosin light chain kinase, smooth muscle isoform X1 [KO:K00907] [EC:2.7.11.18]
127155333  mylk2; myosin light chain kinase 2, skeletal/cardiac muscle [KO:K00907] [EC:2.7.11.18]
127156493  mylk5; myosin light chain kinase, smooth muscle isoform X1 [KO:K00907] [EC:2.7.11.18]
127167115  mylkb; myosin light chain kinase, smooth muscle [KO:K00907] [EC:2.7.11.18]
127173158  mylk4a; myosin light chain kinase 2, skeletal/cardiac muscle isoform X1 [KO:K00907] [EC:2.7.11.18]
127168742  mylk3; myosin light chain kinase 3 isoform X1 [KO:K00907] [EC:2.7.11.18]
127183053  mylk4b; myosin light chain kinase 2, skeletal/cardiac muscle isoform X1 [KO:K00907] [EC:2.7.11.18]
127165713  ppp1cc; serine/threonine-protein phosphatase PP1-gamma catalytic subunit A [KO:K06269] [EC:3.1.3.16]
127156016  ppp1caa; protein phosphatase 1, catalytic subunit, alpha isozyme a [KO:K06269] [EC:3.1.3.16]
127179450  ppp1cb; serine/threonine-protein phosphatase PP1-beta catalytic subunit [KO:K06269] [EC:3.1.3.16]
127168285  serine/threonine-protein phosphatase PP1-beta catalytic subunit [KO:K06269] [EC:3.1.3.16]
127174333  ppp1cab; protein phosphatase 1, catalytic subunit, alpha isozyme b [KO:K06269] [EC:3.1.3.16]
127163965  ppp1r12a; protein phosphatase 1 regulatory subunit 12A isoform X1 [KO:K06270]
127156342  zmp:0000001167; protein phosphatase 1 regulatory subunit 12A isoform X1 [KO:K06270]
127154606  protein phosphatase 1 regulatory subunit 12B isoform X1 [KO:K12329]
127166724  ppp1r12c; protein phosphatase 1 regulatory subunit 12C [KO:K17457]
127170142  myl2b; myosin, light chain 2b, regulatory, cardiac, slow [KO:K10351]
127165543  myl2a; myosin regulatory light chain 2a [KO:K10351]
127169668  myl7; myosin regulatory light chain 2, atrial isoform [KO:K12754]
127154432  myl9a; myosin regulatory light polypeptide 9 isoform X1 [KO:K12755]
127166623  myl9b; myosin regulatory light polypeptide 9b [KO:K12755]
127172130  myl10; myosin regulatory light chain 10 [KO:K12756]
127168615  myl12.1; myosin, light chain 12, genome duplicate 1 [KO:K12757]
127183079  myl12.2; myosin, light chain 12, genome duplicate 2 [KO:K12757]
127173696  mylpfb; myosin regulatory light chain 2, skeletal muscle [KO:K12758]
127163283  mylpfa; myosin regulatory light chain 11 [KO:K12758]
127166705  myh9a; myosin-9a [KO:K10352]
127166922  myh11a; myosin-11a isoform X1 [KO:K10352]
127166957  myh10; myosin-10 isoform X1 [KO:K10352]
127163351  myosin-9 isoform X1 [KO:K10352]
127175882  protein diaphanous homolog 1 isoform X1 [KO:K05740]
127182141  slc9a1b; sodium/hydrogen exchanger 1b isoform X1 [KO:K05742]
127178372  slc9a1a; sodium/hydrogen exchanger 1 isoform X1 [KO:K05742]
127169818  pip5k1bb; phosphatidylinositol 4-phosphate 5-kinase type-1 beta [KO:K00889] [EC:2.7.1.68]
127181997  pip5k1aa; phosphatidylinositol-4-phosphate 5-kinase, type I, alpha, a isoform X1 [KO:K00889] [EC:2.7.1.68]
127154013  pip5k1ca; phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform X1 [KO:K00889] [EC:2.7.1.68]
127172275  pip5k1ba; phosphatidylinositol-4-phosphate 5-kinase, type I, beta a isoform X1 [KO:K00889] [EC:2.7.1.68]
127178390  pip5k1ab; phosphatidylinositol 4-phosphate 5-kinase type-1 alpha isoform X1 [KO:K00889] [EC:2.7.1.68]
127178528  pip5k1cb; phosphatidylinositol-4-phosphate 5-kinase, type I, gamma b isoform X1 [KO:K00889] [EC:2.7.1.68]
127154758  pip4k2ca; phosphatidylinositol 5-phosphate 4-kinase type-2 gamma [KO:K00920] [EC:2.7.1.149]
127155704  pip4k2aa; phosphatidylinositol 5-phosphate 4-kinase type-2 alpha [KO:K00920] [EC:2.7.1.149]
127161287  pip4k2cb; phosphatidylinositol 5-phosphate 4-kinase type-2 gamma isoform X1 [KO:K00920] [EC:2.7.1.149]
127180668  pip4k2ab; phosphatidylinositol 5-phosphate 4-kinase type-2 alpha isoform X1 [KO:K00920] [EC:2.7.1.149]
127170850  pikfyve; 1-phosphatidylinositol 3-phosphate 5-kinase isoform X1 [KO:K00921] [EC:2.7.1.150]
127157580  limk1a; LIM domain kinase 1a [KO:K05743] [EC:2.7.11.1]
127152882  limk1b; LOW QUALITY PROTEIN: LIM domain kinase 1 [KO:K05743] [EC:2.7.11.1]
127165434  limk2; LIM domain kinase 2 [KO:K05744] [EC:2.7.11.1]
127176522  diaph2; protein diaphanous homolog 2 isoform X1 [KO:K05745]
127173477  diaph3; protein diaphanous homolog 3 [KO:K05745]
127178019  zgc:158689; brain-specific angiogenesis inhibitor 1-associated protein 2 [KO:K05627]
127174005  baiap2b; brain-specific angiogenesis inhibitor 1-associated protein 2 isoform X1 [KO:K05627]
127163214  baiap2a; brain-specific angiogenesis inhibitor 1-associated protein 2a isoform X1 [KO:K05627]
127164375  waslb; WASP like actin nucleation promoting factor b isoform X1 [KO:K23612]
127156491  wasla; WASP like actin nucleation promoting factor a isoform X1 [KO:K23612]
127182149  wasf2; wiskott-Aldrich syndrome protein family member 2 [KO:K05748]
127175966  cyfip2; cytoplasmic FMR1-interacting protein 2 isoform X1 [KO:K05749]
127166676  cyfip1; cytoplasmic FMR1-interacting protein 1 homolog [KO:K05749]
127170598  nckap1; nck-associated protein 1 isoform X1 [KO:K05750]
127173529  nckap1l; nck-associated protein 1-like [KO:K05750]
127170601  abi2a; abl interactor 2a isoform X1 [KO:K05751]
127166570  abi2b; abl interactor 2b isoform X1 [KO:K05751]
127172992  brk1; probable protein BRICK1 [KO:K05752]
127182622  wasf1; actin-binding protein WASF1 isoform X1 [KO:K05753]
127168026  zgc:101810; actin-related protein 2 [KO:K17260]
127174872  actr2b; actin-related protein 2-B [KO:K17260]
127183134  actr2a; actin-related protein 2-A [KO:K17260]
127155699  actr3b; actin-related protein 3B isoform X1 [KO:K18584]
127157239  actr3; actin-related protein 3 [KO:K18584]
127156406  zgc:86896; actin-related protein 2/3 complex subunit 1A-A [KO:K05757]
127162688  arpc1a; actin-related protein 2/3 complex subunit 1A [KO:K05757]
127162689  arpc1b; actin-related protein 2/3 complex subunit 1B [KO:K05757]
127171178  arpc2; actin-related protein 2/3 complex subunit 2 [KO:K05758]
127152653  arpc3; actin-related protein 2/3 complex subunit 3 [KO:K05756]
127167186  arpc4; actin-related protein 2/3 complex subunit 4 [KO:K05755]
127173336  arpc4l; actin related protein 2/3 complex, subunit 4, like [KO:K05755]
127170279  arpc5la; actin related protein 2/3 complex, subunit 5-like, a [KO:K05754]
127165620  arpc5lb; actin related protein 2/3 complex, subunit 5-like, b isoform X1 [KO:K05754]
127179829  arpc5a; actin-related protein 2/3 complex subunit 5a [KO:K05754]
127151794  arpc5b; actin-related protein 2/3 complex subunit 5b [KO:K05754]
127157202  actb1; actin, cytoplasmic 1 [KO:K05692]
127158359  actb2; actin, cytoplasmic 2 [KO:K05692]
127153716  profilin-2 isoform X1 [KO:K05759]
127180084  pfn4; profilin-4 isoform X1 [KO:K05759]
127162272  pfn1; profilin-1 [KO:K05759]
127182819  pfn2a; profilin 2a isoform X1 [KO:K05759]
127170116  pxnb; NAC-alpha domain-containing protein 1 isoform X1 [KO:K05760]
127179755  ezra; ezrin a isoform X1 [KO:K08007]
127182746  ezrb; ezrin b [KO:K08007]
127153612  radixin [KO:K05762]
127176408  msnb; moesin b isoform X1 [KO:K05763]
127165037  msna; moesin a isoform X1 [KO:K05763]
127176575  tmsb2; thymosin beta [KO:K05764]
127171007  tmsb4x; thymosin beta-4 [KO:K05764]
127152395  tmsb; thymosin beta [KO:K05764]
127176127  cfl1; cofilin-1 [KO:K05765]
127180209  cfl2; cofilin-2 [KO:K05765]
127174859  cfl1l; non-muscle cofilin 1-like [KO:K05765]
127176159  si:ch211-203d1.3; protein phosphatase Slingshot homolog 3 [KO:K05766] [EC:3.1.3.16 3.1.3.48]
127164962  ssh1a; protein phosphatase Slingshot homolog 1 isoform X1 [KO:K05766] [EC:3.1.3.16 3.1.3.48]
127177096  ssh2a; protein phosphatase Slingshot homolog 2 isoform X1 [KO:K05766] [EC:3.1.3.16 3.1.3.48]
127165595  ssh1b; protein phosphatase Slingshot homolog 1 [KO:K05766] [EC:3.1.3.16 3.1.3.48]
127152396  ssh2b; protein phosphatase Slingshot homolog 2b isoform X1 [KO:K05766] [EC:3.1.3.16 3.1.3.48]
127173669  vclb; vinculin b [KO:K05700]
127174878  vcla; vinculin a isoform X1 [KO:K05700]
127168354  iqgap1; ras GTPase-activating-like protein IQGAP1 [KO:K16848]
127165208  iqgap2; ras GTPase-activating-like protein IQGAP2 [KO:K05767]
127178155  iqgap3; ras GTPase-activating-like protein IQGAP3 [KO:K05767]
127176168  scinlb; LOW QUALITY PROTEIN: scinderin like b [KO:K05768]
127164940  gsnb; gelsolin b isoform X1 [KO:K05768]
127158676  scinla; scinderin like a [KO:K05768]
127152118  gsna; gelsolin a isoform X1 [KO:K05768]
127181767  scin; adseverin isoform X1 [KO:K05768]
127175692  actn1; alpha-actinin-1 isoform X1 [KO:K05699]
127176897  actn4; alpha-actinin-4 isoform X1 [KO:K05699]
127171793  apc; adenomatous polyposis coli protein isoform X1 [KO:K02085]
127172975  apc2; LOW QUALITY PROTEIN: adenomatous polyposis coli protein 2 [KO:K02085]
127155759  spata13; spermatogenesis-associated protein 13 [KO:K05769]
127179927  arhgef4; uncharacterized protein arhgef4 isoform X1 [KO:K05769]
Compound
C00681  1-Acyl-sn-glycerol 3-phosphate
C01996  Acetylcholine
C04637  1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C11554  1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
Reference
PMID:14744429
  Authors
Burridge K, Wennerberg K.
  Title
Rho and Rac take center stage.
  Journal
Cell 116:167-79 (2004)
DOI:10.1016/S0092-8674(04)00003-0
Reference
PMID:11082269
  Authors
Schmitz AA, Govek EE, Bottner B, Van Aelst L.
  Title
Rho GTPases: signaling, migration, and invasion.
  Journal
Exp Cell Res 261:1-12 (2000)
DOI:10.1006/excr.2000.5049
Reference
PMID:11152757
  Authors
Takai Y, Sasaki T, Matozaki T.
  Title
Small GTP-binding proteins.
  Journal
Physiol Rev 81:153-208 (2001)
DOI:10.1152/physrev.2001.81.1.153
Reference
PMID:12700767
  Authors
Pollard TD.
  Title
The cytoskeleton, cellular motility and the reductionist agenda.
  Journal
Nature 422:741-5 (2003)
DOI:10.1038/nature01598
Reference
PMID:14657486
  Authors
Ridley AJ, Schwartz MA, Burridge K, Firtel RA, Ginsberg MH, Borisy G, Parsons JT, Horwitz AR.
  Title
Cell migration: integrating signals from front to back.
  Journal
Science 302:1704-9 (2003)
DOI:10.1126/science.1092053
Reference
PMID:11082272
  Authors
Sastry SK, Burridge K.
  Title
Focal adhesions: a nexus for intracellular signaling and cytoskeletal dynamics.
  Journal
Exp Cell Res 261:25-36 (2000)
DOI:10.1006/excr.2000.5043
Reference
PMID:10574699
  Authors
Fukata M, Nakagawa M, Kuroda S, Kaibuchi K.
  Title
Cell adhesion and Rho small GTPases.
  Journal
J Cell Sci 112 ( Pt 24):4491-500 (1999)
Related
pathway
lroh04010  MAPK signaling pathway
lroh04510  Focal adhesion
lroh04520  Adherens junction
KO pathway
ko04810   
LinkDB

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