KEGG   PATHWAY: msam04010
Entry
msam04010                   Pathway                                
Name
MAPK signaling pathway - Micropterus salmoides (largemouth bass)
Description
The mitogen-activated protein kinase (MAPK) cascade is a highly conserved module that is involved in various cellular functions, including cell proliferation, differentiation and migration. Mammals express at least four distinctly regulated groups of MAPKs, extracellular signal-related kinases (ERK)-1/2, Jun amino-terminal kinases (JNK1/2/3), p38 proteins (p38alpha/beta/gamma/delta) and ERK5, that are activated by specific MAPKKs: MEK1/2 for ERK1/2, MKK3/6 for the p38, MKK4/7 (JNKK1/2) for the JNKs, and MEK5 for ERK5. Each MAPKK, however, can be activated by more than one MAPKKK, increasing the complexity and diversity of MAPK signalling. Presumably each MAPKKK confers responsiveness to distinct stimuli. For example, activation of ERK1/2 by growth factors depends on the MAPKKK c-Raf, but other MAPKKKs may activate ERK1/2 in response to pro-inflammatory stimuli.
Class
Environmental Information Processing; Signal transduction
Pathway map
msam04010  MAPK signaling pathway
msam04010

Other DBs
GO: 0000165
Organism
Micropterus salmoides (largemouth bass) [GN:msam]
Gene
119898592  cacna1ab; calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, b isoform X1 [KO:K04344]
119887893  cacna1aa; LOW QUALITY PROTEIN: voltage-dependent P/Q-type calcium channel subunit alpha-1A [KO:K04344]
119892109  cacna1ba; calcium channel, voltage-dependent, N type, alpha 1B subunit, a [KO:K04849]
119914522  cacna1bb; voltage-dependent N-type calcium channel subunit alpha-1B isoform X1 [KO:K04849]
119918210  cacna1c; voltage-dependent L-type calcium channel subunit alpha-1C isoform X1 [KO:K04850]
119905703  cacna1db; voltage-dependent L-type calcium channel subunit alpha-1D [KO:K04851]
119886716  cacna1da; calcium channel, voltage-dependent, L type, alpha 1D subunit, a [KO:K04851]
119900716  voltage-dependent R-type calcium channel subunit alpha-1E isoform X1 [KO:K04852]
119902018  cacna1eb; voltage-dependent R-type calcium channel subunit alpha-1E isoform X1 [KO:K04852]
119905055  cacna1fb; calcium channel, voltage-dependent, L type, alpha 1F subunit [KO:K04853]
119905094  cacna1fa; voltage-dependent L-type calcium channel subunit alpha-1D [KO:K04853]
119916493  cacna1g; voltage-dependent T-type calcium channel subunit alpha-1G [KO:K04854]
119886016  cacna1ha; voltage-dependent T-type calcium channel subunit alpha-1I [KO:K04855]
119882485  voltage-dependent T-type calcium channel subunit alpha-1H-like [KO:K04856]
119898797  voltage-dependent T-type calcium channel subunit alpha-1I-like [KO:K04856]
119888036  cacna1ia; voltage-dependent T-type calcium channel subunit alpha-1I isoform X1 [KO:K04856]
119905492  dihydropyridine-sensitive L-type skeletal muscle calcium channel subunit alpha-1-like [KO:K04857]
119886874  dihydropyridine-sensitive L-type skeletal muscle calcium channel subunit alpha-1-like [KO:K04857]
119918165  cacna2d1a; voltage-dependent calcium channel subunit alpha-2/delta-1a isoform X1 [KO:K04858]
119894006  voltage-dependent calcium channel subunit alpha-2/delta-1 isoform X1 [KO:K04858]
119886343  cacna2d2a; voltage-dependent calcium channel subunit alpha-2/delta-2a isoform X1 [KO:K04859]
119886678  voltage-dependent calcium channel subunit alpha-2/delta-2-like isoform X1 [KO:K04859]
119906003  cacna2d3a; voltage-dependent calcium channel subunit alpha-2/delta-3 isoform X1 [KO:K04860]
119886958  voltage-dependent calcium channel subunit alpha-2/delta-3-like isoform X1 [KO:K04860]
119917948  cacna2d4a; voltage-dependent calcium channel subunit alpha-2/delta-4 isoform X1 [KO:K04861]
119884490  LOW QUALITY PROTEIN: voltage-dependent calcium channel subunit alpha-2/delta-4-like [KO:K04861]
119893321  voltage-dependent calcium channel subunit alpha-2/delta-4-like [KO:K04861]
119893031  cacnb1; voltage-dependent L-type calcium channel subunit beta-1 isoform X1 [KO:K04862]
119910985  cacnb2a; voltage-dependent L-type calcium channel subunit beta-2a isoform X1 [KO:K04863]
119901900  cacnb2b; voltage-dependent L-type calcium channel subunit beta-2b isoform X1 [KO:K04863]
119905280  voltage-dependent L-type calcium channel subunit beta-3-like isoform X1 [KO:K04864]
119905505  cacnb3b; voltage-dependent L-type calcium channel subunit beta-4 isoform X1 [KO:K04864]
119904440  cacnb4a; voltage-dependent L-type calcium channel subunit beta-4a isoform X1 [KO:K04865]
119903240  voltage-dependent L-type calcium channel subunit beta-4-like isoform X1 [KO:K04865]
119899349  cacng1a; calcium channel, voltage-dependent, gamma subunit 1a [KO:K04866]
119888717  cacng1b; voltage-dependent calcium channel gamma-1 subunit [KO:K04866]
119898613  voltage-dependent calcium channel gamma-2 subunit-like [KO:K04867]
119894177  cacng2a; calcium channel, voltage-dependent, gamma subunit 2a [KO:K04867]
119885901  cacng3b; voltage-dependent calcium channel gamma-3 subunit [KO:K04868]
119899346  voltage-dependent calcium channel gamma-4 subunit-like isoform X1 [KO:K04869]
119888728  cacng4b; calcium channel, voltage-dependent, gamma subunit 4b [KO:K04869]
119899345  voltage-dependent calcium channel gamma-5 subunit [KO:K04870]
119889234  cacng5b; voltage-dependent calcium channel gamma-5 subunit [KO:K04870]
119897493  cacng6b; voltage-dependent calcium channel gamma-6 subunit [KO:K04871]
119908171  voltage-dependent calcium channel gamma-6 subunit-like [KO:K04871]
119897495  cacng7b; voltage-dependent calcium channel gamma-7 subunit [KO:K04872]
119908169  voltage-dependent calcium channel gamma-7 subunit-like [KO:K04872]
119897494  cacng8b; voltage-dependent calcium channel gamma-4 subunit [KO:K04873]
119908130  voltage-dependent calcium channel gamma-4 subunit-like [KO:K04873]
119896511  prkacaa; protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a isoform X1 [KO:K04345] [EC:2.7.11.11]
119899469  prkacab; cAMP-dependent protein kinase catalytic subunit alpha isoform X1 [KO:K04345] [EC:2.7.11.11]
119900632  prkacba; protein kinase, cAMP-dependent, catalytic, beta a isoform X1 [KO:K04345] [EC:2.7.11.11]
119902028  prkacbb; protein kinase, cAMP-dependent, catalytic, beta b [KO:K04345] [EC:2.7.11.11]
119899340  protein kinase C alpha type-like isoform X1 [KO:K02677] [EC:2.7.11.13]
119889216  si:ch73-374l24.1; protein kinase C alpha type isoform X1 [KO:K02677] [EC:2.7.11.13]
119898769  protein kinase C beta type-like isoform X1 [KO:K19662] [EC:2.7.11.13]
119885905  prkcbb; protein kinase C beta type isoform X1 [KO:K19662] [EC:2.7.11.13]
119897496  prkcg; protein kinase C gamma type [KO:K19663] [EC:2.7.11.13]
119898751  gna12a; guanine nucleotide-binding protein subunit alpha-12a [KO:K04346]
119898752  guanine nucleotide-binding protein subunit alpha-12 [KO:K04346]
119901217  si:dkey-44g17.6; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 [KO:K04347]
119888289  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7-like [KO:K04347]
119902266  gng12a; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12a [KO:K04347]
119911555  serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X1 [KO:K04348] [EC:3.1.3.16]
119892413  ppp3cca; protein phosphatase 3, catalytic subunit, gamma isozyme, a isoform X1 [KO:K04348] [EC:3.1.3.16]
119894974  ppp3ca; serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X1 [KO:K04348] [EC:3.1.3.16]
119914377  ppp3ccb; protein phosphatase 3, catalytic subunit, gamma isozyme, b isoform X1 [KO:K04348] [EC:3.1.3.16]
119889209  ppp3cb; serine/threonine-protein phosphatase 2B catalytic subunit beta isoform isoform X1 [KO:K04348] [EC:3.1.3.16]
119917717  calcineurin subunit B type 1-like [KO:K06268]
119915078  ppp3r1b; calcineurin subunit B type 1b [KO:K06268]
119890553  ras-specific guanine nucleotide-releasing factor 1-like isoform X1 [KO:K04349]
119894351  rasgrf1; ras-specific guanine nucleotide-releasing factor 1 [KO:K04349]
119891634  rasgrf2b; ras-specific guanine nucleotide-releasing factor 2 isoform X1 [KO:K12326]
119914532  rasgrf2a; ras-specific guanine nucleotide-releasing factor 2 isoform X1 [KO:K12326]
119883549  rasgrp4; RAS guanyl-releasing protein 4 isoform X1 [KO:K04350]
119910297  RAS guanyl-releasing protein 1-like [KO:K04350]
119912454  RAS guanyl-releasing protein 2-like isoform X1 [KO:K12361]
119917380  rasgrp3; ras guanyl-releasing protein 3 isoform X1 [KO:K12362]
119888255  rapgef2; rap guanine nucleotide exchange factor 2 isoform X1 [KO:K08018]
119883190  nf1a; LOW QUALITY PROTEIN: neurofibromin [KO:K08052]
119891428  rasa1a; ras GTPase-activating protein 1 [KO:K04352]
119882876  rasa2; ras GTPase-activating protein 2 [KO:K08053]
119905851  ras-related protein Rap-1A [KO:K04353]
119885910  ras-related protein Rap-1A-like [KO:K04353]
119895189  ras-related protein Rap-1b [KO:K07836]
119888559  egf; pro-epidermal growth factor [KO:K04357]
119884981  serine-rich adhesin for platelets-like isoform X1 [KO:K08774]
119886804  tgfa; protransforming growth factor alpha isoform X1 [KO:K08774]
119892240  proepiregulin-like [KO:K09784]
119891216  areg; proheparin-binding EGF-like growth factor [KO:K09782]
119889029  putative fibroblast growth factor 1 [KO:K18496]
119895886  putative fibroblast growth factor 1 isoform X1 [KO:K18496]
119889114  fgf2; fibroblast growth factor 2 [KO:K18497]
119882059  LOW QUALITY PROTEIN: fibroblast growth factor 7-like [KO:K04358]
119903502  fgf9; fibroblast growth factor 4A [KO:K04358]
119890485  fgf4; fibroblast growth factor 4 [KO:K04358]
119890560  fgf3; fibroblast growth factor 3 [KO:K04358]
119890793  fgf7; fibroblast growth factor 7 [KO:K04358]
119916885  fgf8a; fibroblast growth factor 8 [KO:K04358]
119891173  fgf10b; fibroblast growth factor 10b [KO:K04358]
119891640  fgf17; fibroblast growth factor 17 isoform X1 [KO:K04358]
119898562  fgf8b; fibroblast growth factor 8b [KO:K04358]
119892186  fgf5; fibroblast growth factor 5 [KO:K04358]
119918424  fibroblast growth factor 6-like [KO:K04358]
119899385  fibroblast growth factor 20-like [KO:K04358]
119893584  fgf6a; fibroblast growth factor 6a [KO:K04358]
119900909  fgf22; fibroblast growth factor 22 [KO:K04358]
119889001  fgf20b; fibroblast growth factor 20b [KO:K04358]
119889133  fgf24; fibroblast growth factor 24 isoform X1 [KO:K04358]
119889152  fgf18a; fibroblast growth factor 18a isoform X1 [KO:K04358]
119889336  fibroblast growth factor 4A-like [KO:K04358]
119915029  fgf10a; fibroblast growth factor 10a [KO:K04358]
119889410  fgf16; fibroblast growth factor 16 isoform X1 [KO:K04358]
119890789  fgf19; fibroblast growth factor 19 [KO:K22603]
119916362  fgf21; fibroblast growth factor 21 [KO:K22429]
119918427  fgf23; fibroblast growth factor 23 [KO:K22428]
119893583  uncharacterized protein LOC119893583 [KO:K22428]
119906156  ngfa; neurotrophin-7 [KO:K02582]
119886942  ngfb; nerve growth factor [KO:K02582]
119889767  bdnf; brain-derived neurotrophic factor isoform X1 [KO:K04355]
119918506  ntf3; neurotrophin-3 [KO:K04356]
119894945  ins; insulin [KO:K04526]
119888918  insb; preproinsulin b [KO:K04526]
119917907  igf1; insulin-like growth factor I [KO:K05459]
119905971  insulin-like growth factor I [KO:K05459]
119893407  igf2b; insulin-like growth factor 2b [KO:K13769]
119898647  platelet-derived growth factor subunit A-like [KO:K04359]
119889692  pdgfab; platelet-derived growth factor alpha polypeptide b [KO:K04359]
119898635  si:ch211-79m20.1; G-box-binding factor isoform X1 [KO:K17386]
119883119  pdgfd; platelet-derived growth factor D [KO:K05450]
119889019  pdgfc; platelet-derived growth factor C isoform X1 [KO:K05450]
119918363  uncharacterized protein LOC119918363 [KO:K05461]
119919143  uncharacterized protein LOC119919143 [KO:K05461]
119893866  kitlga; kit ligand a [KO:K05461]
119896891  vegfaa; vascular endothelial growth factor A-A isoform X1 [KO:K05448]
119884033  vascular endothelial growth factor A-A-like isoform X1 [KO:K05448]
119908556  vegfab; vascular endothelial growth factor Ab isoform X1 [KO:K05448]
119888221  vegfba; vascular endothelial growth factor A [KO:K05448]
119910658  pgfb; placenta growth factor [KO:K16859]
119908452  vascular endothelial growth factor A-like [KO:K16859]
119890242  vegfd; vascular endothelial growth factor D isoform X1 [KO:K05449]
119904020  vascular endothelial growth factor C-like isoform X1 [KO:K05449]
119899827  vegfc; vascular endothelial growth factor C [KO:K05449]
119918297  hgfa; hepatocyte growth factor a isoform X1 [KO:K05460]
119893453  LOW QUALITY PROTEIN: hepatocyte growth factor [KO:K05460]
119885606  angpt4; angiopoietin-1 [KO:K05465]
119907392  angpt1; angiopoietin-1 [KO:K05465]
119882191  angiopoietin-2-like [KO:K05466]
119917231  angpt2a; angiopoietin-2a [KO:K05466]
119907918  angpt2b; angiopoietin-2b isoform X1 [KO:K05466]
119911013  efna2a; ephrin-A2 [KO:K05462]
119897591  efna1b; ephrin-A1b [KO:K05462]
119897592  efna3b; ephrin-A3b [KO:K05462]
119897593  si:dkey-246i14.3; ephrin-A4 [KO:K05462]
119891993  efna5b; ephrin-A5b isoform X1 [KO:K05462]
119907427  efna3a; ephrin-A3 [KO:K05462]
119907454  efna1a; ephrin-A1a isoform X1 [KO:K05462]
119914459  ephrin-A5b-like [KO:K05462]
119888878  ephrin-A2-like isoform X1 [KO:K05462]
119889221  ephrin-A2-like [KO:K05462]
119891118  glial cell line-derived neurotrophic factor-like [KO:K05452]
119914515  gdnfa; glial cell line-derived neurotrophic factor [KO:K05452]
119901848  neurturin-like [KO:K25414]
119902259  uncharacterized protein LOC119902259 [KO:K25415]
119887725  persephin-like [KO:K25416]
119898759  persephin-like [KO:K25416]
119913984  melanoma receptor tyrosine-protein kinase-like [KO:K04361] [EC:2.7.10.1]
119901961  egfra; epidermal growth factor receptor [KO:K04361] [EC:2.7.10.1]
119915537  erbb2; receptor tyrosine-protein kinase erbB-2 isoform X1 [KO:K05083] [EC:2.7.10.1]
119906034  erbb3b; receptor tyrosine-protein kinase erbB-3b [KO:K05084] [EC:2.7.10.1]
119886809  erbb3a; receptor tyrosine-protein kinase erbB-3a [KO:K05084] [EC:2.7.10.1]
119903962  erbb4b; receptor tyrosine-protein kinase erbB-4 isoform X1 [KO:K05085] [EC:2.7.10.1]
119904608  receptor tyrosine-protein kinase erbB-4-like isoform X1 [KO:K05085] [EC:2.7.10.1]
119891967  fgfr1a; fibroblast growth factor receptor 1-A isoform X1 [KO:K04362] [EC:2.7.10.1]
119914512  LOW QUALITY PROTEIN: fibroblast growth factor receptor 1-A-like [KO:K04362] [EC:2.7.10.1]
119916902  fgfr2; fibroblast growth factor receptor 2 isoform X1 [KO:K05093] [EC:2.7.10.1]
119910102  fgfr3; LOW QUALITY PROTEIN: fibroblast growth factor receptor 3 [KO:K05094] [EC:2.7.10.1]
119895152  fgfr4; fibroblast growth factor receptor 4 isoform X1 [KO:K05095] [EC:2.7.10.1]
119916226  ngfrb; nerve growth factor receptor b [KO:K02583]
119897709  nradd; tumor necrosis factor receptor superfamily member 16 [KO:K02583]
119893437  ngfra; tumor necrosis factor receptor superfamily member 16 [KO:K02583]
119897108  ntrk1; high affinity nerve growth factor receptor [KO:K03176] [EC:2.7.10.1]
119892041  ntrk2a; neurotrophic tyrosine kinase, receptor, type 2a isoform X1 [KO:K04360] [EC:2.7.10.1]
119914353  ntrk2b; neurotrophic tyrosine kinase, receptor, type 2b isoform X1 [KO:K04360] [EC:2.7.10.1]
119901871  insra; insulin receptor a isoform X1 [KO:K04527] [EC:2.7.10.1]
119900689  insulin receptor-like [KO:K04527] [EC:2.7.10.1]
119894125  igf1ra; insulin-like growth factor 1a receptor [KO:K05087] [EC:2.7.10.1]
119889848  igf1rb; insulin-like growth factor 1b receptor [KO:K05087] [EC:2.7.10.1]
119901064  pdgfra; platelet-derived growth factor receptor alpha [KO:K04363] [EC:2.7.10.1]
119918588  LOW QUALITY PROTEIN: platelet-derived growth factor receptor beta-like [KO:K05089] [EC:2.7.10.1]
119888610  pdgfrb; platelet-derived growth factor receptor beta [KO:K05089] [EC:2.7.10.1]
119895825  platelet-derived growth factor receptor beta-like [KO:K05089] [EC:2.7.10.1]
119918589  macrophage colony-stimulating factor 1 receptor 1-like [KO:K05090] [EC:2.7.10.1]
119895082  csf1rb; macrophage colony-stimulating factor 1 receptor 2 [KO:K05090] [EC:2.7.10.1]
119888609  LOW QUALITY PROTEIN: macrophage colony-stimulating factor 1 receptor 1-like [KO:K05090] [EC:2.7.10.1]
119899140  kitb; KIT proto-oncogene, receptor tyrosine kinase b isoform X1 [KO:K05091] [EC:2.7.10.1]
119901063  kita; mast/stem cell growth factor receptor kita isoform X1 [KO:K05091] [EC:2.7.10.1]
119887189  receptor-type tyrosine-protein kinase FLT3-like [KO:K05092] [EC:2.7.10.1]
119909737  flt3; LOW QUALITY PROTEIN: receptor-type tyrosine-protein kinase FLT3 [KO:K05092] [EC:2.7.10.1]
119888301  kdrl; vascular endothelial growth factor receptor kdr-like [KO:K05096] [EC:2.7.10.1]
119909684  flt1; vascular endothelial growth factor receptor 1 isoform X1 [KO:K05096] [EC:2.7.10.1]
119888532  vascular endothelial growth factor receptor 3-like [KO:K05097] [EC:2.7.10.1]
119889380  flt4; LOW QUALITY PROTEIN: vascular endothelial growth factor receptor 3 [KO:K05097] [EC:2.7.10.1]
119901062  kdr; vascular endothelial growth factor receptor 2 isoform X1 [KO:K05098] [EC:2.7.10.1]
119894195  met; hepatocyte growth factor receptor [KO:K05099] [EC:2.7.10.1]
119905887  epha2b; ephrin type-A receptor 2 isoform X1 [KO:K05103] [EC:2.7.10.1]
119886539  epha2a; ephrin type-A receptor 2a [KO:K05103] [EC:2.7.10.1]
119917613  ret; proto-oncogene tyrosine-protein kinase receptor Ret isoform X1 [KO:K05126] [EC:2.7.10.1]
119883760  grb2b; growth factor receptor-bound protein 2b [KO:K04364]
119899870  son of sevenless homolog 1-like isoform X1 [KO:K03099]
119910225  sos2; son of sevenless homolog 2 [KO:K03099]
119893575  hrasb; HRas proto-oncogene, GTPase b [KO:K02833]
119893343  kras; GTPase KRas [KO:K07827]
119886647  zgc:55558 [KO:K07827]
119890240  rras2; ras-related protein R-Ras2 isoform X1 [KO:K07830]
119919084  rras; ras-related protein R-Ras [KO:K07830]
119903871  si:ch73-116o1.2; ras-related protein M-Ras [KO:K07831]
119891482  araf; serine/threonine-protein kinase A-Raf [KO:K08845] [EC:2.7.11.1]
119882013  LOW QUALITY PROTEIN: serine/threonine-protein kinase B-raf-like [KO:K04365] [EC:2.7.11.1]
119917992  braf; LOW QUALITY PROTEIN: serine/threonine-protein kinase B-raf [KO:K04365] [EC:2.7.11.1]
119905315  raf1a; raf-1 proto-oncogene, serine/threonine kinase a isoform X1 [KO:K04366] [EC:2.7.11.1]
119893612  map2k1; dual specificity mitogen-activated protein kinase kinase 1 isoform X1 [KO:K04368] [EC:2.7.12.2]
119900881  map2k2a; LOW QUALITY PROTEIN: dual specificity mitogen-activated protein kinase kinase 2a [KO:K04369] [EC:2.7.12.2]
119902918  map2k2b; dual specificity mitogen-activated protein kinase kinase 2b [KO:K04369] [EC:2.7.12.2]
119910200  lamtor3; ragulator complex protein LAMTOR3 [KO:K04370]
119891295  mapk1; mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
119886325  mapk3; mitogen-activated protein kinase 3 [KO:K04371] [EC:2.7.11.24]
119900448  mknk2b; MAP kinase-interacting serine/threonine-protein kinase 2b [KO:K04372] [EC:2.7.11.1]
119900821  mknk1; MAP kinase-interacting serine/threonine-protein kinase 1 [KO:K04372] [EC:2.7.11.1]
119910514  ribosomal protein S6 kinase alpha-1 isoform X1 [KO:K04373] [EC:2.7.11.1]
119890805  ribosomal protein S6 kinase alpha-2-like [KO:K04373] [EC:2.7.11.1]
119884830  ribosomal protein S6 kinase alpha-3-like [KO:K04373] [EC:2.7.11.1]
119888396  rps6kal; ribosomal protein S6 kinase alpha-6 isoform X1 [KO:K04373] [EC:2.7.11.1]
119898630  atf4a; cyclic AMP-dependent transcription factor ATF-4 isoform X1 [KO:K04374]
119885408  atf4b; activating transcription factor 4b [KO:K04374]
119905054  elk1; LOW QUALITY PROTEIN: ETS domain-containing protein Elk-1 [KO:K04375]
119885667  elk4; ETS domain-containing protein Elk-4 [KO:K04376]
119882023  mych; myelocytomatosis oncogene homolog [KO:K04377]
119911475  myca; transcriptional regulator Myc-A [KO:K04377]
119902666  transcriptional regulator Myc-1-like [KO:K04377]
119917728  srfb; serum response factor b isoform X1 [KO:K04378]
119899886  serum response factor-like isoform X1 [KO:K04378]
119908415  proto-oncogene c-Fos-like [KO:K04379]
119909126  proto-oncogene c-Fos-like [KO:K04379]
119909776  fosaa; proto-oncogene c-Fos [KO:K04379]
119916108  mapta; microtubule-associated protein tau [KO:K04380]
119896120  maptb; microtubule-associated protein tau [KO:K04380]
119897808  stmn1b; stathmin 1b [KO:K04381]
119907835  stmn1a; stathmin 1a [KO:K04381]
119882257  cytosolic phospholipase A2 gamma-like isoform X1 [KO:K16342] [EC:3.1.1.4]
119900432  pla2g4ab; cytosolic phospholipase A2 [KO:K16342] [EC:3.1.1.4]
119896422  cytosolic phospholipase A2 gamma-like [KO:K16342] [EC:3.1.1.4]
119897144  tumor necrosis factor-like [KO:K03156]
119906688  tnfa; tumor necrosis factor a (TNF superfamily, member 2) [KO:K03156]
119882881  tgfb1a; transforming growth factor, beta 1a [KO:K13375]
119896887  tgfb2; transforming growth factor beta-2 proprotein [KO:K13376]
119889077  tgfb5; transforming growth factor beta-2 proprotein [KO:K13376]
119910740  tgfb3; transforming growth factor beta-3 proprotein [KO:K13377]
119909133  transforming growth factor beta-3 proprotein-like [KO:K13377]
119897443  tnfrsf1a; tumor necrosis factor receptor superfamily member 1A isoform X1 [KO:K03158]
119904455  interleukin-1 receptor type 1-like [KO:K04386]
119882583  interleukin-1 receptor accessory protein [KO:K04723]
119905834  tgfbr1b; TGF-beta receptor type-1b [KO:K04674] [EC:2.7.11.30]
119903766  tgfbr2l; TGF-beta receptor type-2 isoform X1 [KO:K04388] [EC:2.7.11.30]
119898112  tgfbr2b; TGF-beta receptor type-2 [KO:K04388] [EC:2.7.11.30]
119907257  TGF-beta receptor type-2-like [KO:K04388] [EC:2.7.11.30]
119901000  faslg; tumor necrosis factor ligand superfamily member 6 [KO:K04389]
119888531  cd40lg; CD40 ligand [KO:K04389]
119904788  tumor necrosis factor receptor superfamily member 6-like [KO:K04390]
119917367  tumor necrosis factor receptor superfamily member 6-like [KO:K04390]
119889305  rac1b; ras-related C3 botulinum toxin substrate 1b [KO:K04392]
119915421  ras-related C3 botulinum toxin substrate 1 [KO:K04392]
119898608  rac2; ras-related C3 botulinum toxin substrate 2 [KO:K07860]
119915443  rac3b; ras-related C3 botulinum toxin substrate 3b isoform X1 [KO:K07861]
119897425  cdc42l; cell division cycle 42, like [KO:K04393]
119905238  cell division control protein 42 homolog isoform X1 [KO:K04393]
119885487  cell division control protein 42 homolog [KO:K04393]
119907070  cell division control protein 42 homolog [KO:K04393]
119890025  tradd; tumor necrosis factor receptor type 1-associated DEATH domain protein [KO:K03171]
119898808  casp3a; caspase-3a [KO:K02187] [EC:3.4.22.56]
119888653  caspase-3-like [KO:K02187] [EC:3.4.22.56]
119892126  TNF receptor-associated factor 2-like isoform X1 [KO:K03173] [EC:2.3.2.27]
119914658  TNF receptor-associated factor 2-like [KO:K03173] [EC:2.3.2.27]
119914703  traf2b; TNF receptor-associated factor 2 [KO:K03173] [EC:2.3.2.27]
119906993  daxx; death domain-associated protein 6 [KO:K02308]
119910303  myd88; myeloid differentiation primary response protein MyD88 [KO:K04729]
119905524  irak1; interleukin-1 receptor-associated kinase 1 isoform X1 [KO:K04730] [EC:2.7.11.1]
119893462  irak4; interleukin-1 receptor-associated kinase 4 [KO:K04733] [EC:2.7.11.1]
119889757  traf6; TNF receptor-associated factor 6 [KO:K03175] [EC:2.3.2.27]
119910438  growth arrest and DNA damage-inducible protein GADD45 beta-like [KO:K04402]
119892201  gadd45ga; growth arrest and DNA-damage-inducible, gamma a [KO:K04402]
119901218  gadd45ab; growth arrest and DNA-damage-inducible, alpha, b [KO:K04402]
119902265  gadd45aa; growth arrest and DNA-damage-inducible, alpha, a [KO:K04402]
119888990  growth arrest and DNA damage-inducible protein GADD45 beta-like [KO:K04402]
119915100  gadd45gb.1; growth arrest and DNA-damage-inducible, gamma b, tandem duplicate 1 [KO:K04402]
119915101  growth arrest and DNA damage-inducible protein GADD45 gamma-like [KO:K04402]
119898614  tab1; TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 isoform X1 [KO:K04403]
119908779  tab2; TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 isoform X1 [KO:K04404]
119912843  ecsit; evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial [KO:K04405]
119917079  mitogen-activated protein kinase kinase kinase kinase 3-like isoform X1 [KO:K04406] [EC:2.7.11.1]
119899874  mitogen-activated protein kinase kinase kinase kinase 3-like isoform X1 [KO:K04406] [EC:2.7.11.1]
119904449  mitogen-activated protein kinase kinase kinase kinase 4-like isoform X1 [KO:K04407] [EC:2.7.11.1]
119888226  si:zfos-2326c3.2; mitogen-activated protein kinase kinase kinase kinase 4 isoform X1 [KO:K04407] [EC:2.7.11.1]
119902815  mitogen-activated protein kinase kinase kinase kinase 4-like isoform X1 [KO:K04407] [EC:2.7.11.1]
119883141  pak1; serine/threonine-protein kinase PAK 1 [KO:K04409] [EC:2.7.11.1]
119910844  serine/threonine-protein kinase PAK 2-like [KO:K04410] [EC:2.7.11.1]
119901041  pak2b; serine/threonine-protein kinase PAK 2b [KO:K04410] [EC:2.7.11.1]
119885604  serine/threonine-protein kinase 4-like [KO:K04411]
119907170  stk3; serine/threonine-protein kinase 3 [KO:K04412]
119911801  map4k2; mitogen-activated protein kinase kinase kinase kinase 2 isoform X1 [KO:K04414] [EC:2.7.11.1]
119906521  map3k8; mitogen-activated protein kinase kinase kinase 8 isoform X1 [KO:K04415] [EC:2.7.11.25]
119913424  mitogen-activated protein kinase kinase kinase 11 [KO:K04419] [EC:2.7.11.25]
119900363  map3k2; mitogen-activated protein kinase kinase kinase 2 [KO:K04420] [EC:2.7.11.25]
119893582  map3k3; mitogen-activated protein kinase kinase kinase 3 [KO:K04421] [EC:2.7.11.25]
119910267  map3k22; mitogen-activated protein kinase kinase kinase 22 [KO:K04421] [EC:2.7.11.25]
119887743  map3k9; mitogen-activated protein kinase kinase kinase 9 [KO:K04417] [EC:2.7.11.25]
119882953  map3k10; mitogen-activated protein kinase kinase kinase 10 [KO:K04418] [EC:2.7.11.25]
119916821  map3k21; mitogen-activated protein kinase kinase kinase 21 isoform X1 [KO:K17534] [EC:2.7.11.25]
119904911  map3k12; mitogen-activated protein kinase kinase kinase 12 [KO:K04423] [EC:2.7.11.25]
119885810  mitogen-activated protein kinase kinase kinase 12-like isoform X1 [KO:K04423] [EC:2.7.11.25]
119904001  si:ch211-45c16.2; LOW QUALITY PROTEIN: mitogen-activated protein kinase kinase kinase 13 [KO:K04422] [EC:2.7.11.25]
119904106  zak; mitogen-activated protein kinase kinase kinase 20 isoform X1 [KO:K04424] [EC:2.7.11.25]
119902201  mitogen-activated protein kinase kinase kinase 7-like [KO:K04424] [EC:2.7.11.25]
119897276  si:ch211-1i11.3; mitogen-activated protein kinase kinase kinase 5 isoform X1 [KO:K04426] [EC:2.7.11.25]
119909551  map3k5; mitogen-activated protein kinase kinase kinase 5 isoform X1 [KO:K04426] [EC:2.7.11.25]
119911008  mitogen-activated protein kinase kinase kinase 7-like [KO:K04427] [EC:2.7.11.25]
119908660  map3k7; mitogen-activated protein kinase kinase kinase 7 isoform X1 [KO:K04427] [EC:2.7.11.25]
119917295  map3k4; mitogen-activated protein kinase kinase kinase 4 isoform X1 [KO:K04428] [EC:2.7.11.25]
119882378  taok1a; serine/threonine-protein kinase TAO1 [KO:K04429] [EC:2.7.11.1]
119916245  taok2b; serine/threonine-protein kinase TAO2 isoform X1 [KO:K04429] [EC:2.7.11.1]
119891103  taok3a; serine/threonine-protein kinase TAO3 isoform X1 [KO:K04429] [EC:2.7.11.1]
119894923  taok1b; LOW QUALITY PROTEIN: serine/threonine-protein kinase TAO1 [KO:K04429] [EC:2.7.11.1]
119895278  taok2a; serine/threonine-protein kinase TAO2 isoform X1 [KO:K04429] [EC:2.7.11.1]
119914381  taok3b; serine/threonine-protein kinase TAO3 [KO:K04429] [EC:2.7.11.1]
119894592  dual specificity mitogen-activated protein kinase kinase 4-like isoform X1 [KO:K04430] [EC:2.7.12.2]
119915646  map2k4b; dual specificity mitogen-activated protein kinase kinase 4b isoform X1 [KO:K04430] [EC:2.7.12.2]
119899297  map2k7; dual specificity mitogen-activated protein kinase kinase 7 isoform X1 [KO:K04431] [EC:2.7.12.2]
119890456  dual specificity mitogen-activated protein kinase kinase 6-like [KO:K04433] [EC:2.7.12.2]
119915650  map2k6; dual specificity mitogen-activated protein kinase kinase 6 isoform X1 [KO:K04433] [EC:2.7.12.2]
119890605  C-Jun-amino-terminal kinase-interacting protein 1-like [KO:K04434]
119890838  mapk8ip1b; C-Jun-amino-terminal kinase-interacting protein 1 [KO:K04434]
119893932  C-Jun-amino-terminal kinase-interacting protein 1-like isoform X1 [KO:K04434]
119893769  mapk8ip2; LOW QUALITY PROTEIN: C-Jun-amino-terminal kinase-interacting protein 2 [KO:K04435]
119886424  mapk8ip3; C-Jun-amino-terminal kinase-interacting protein 3 isoform X1 [KO:K04436]
119905764  flna; filamin-A isoform X1 [KO:K04437]
119883403  crk; adapter molecule crk isoform X1 [KO:K04438]
119895044  adapter molecule crk-like [KO:K04438]
119914247  crkl; crk-like protein [KO:K04438]
119911316  arrestin red cell-like [KO:K04439]
119883599  arrb1; beta-arrestin-1 isoform X1 [KO:K04439]
119895627  arrestin red cell isoform X1 [KO:K04439]
119917030  mapk8a; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
119888580  mapk9; mitogen-activated protein kinase 9 isoform X1 [KO:K04440] [EC:2.7.11.24]
119915031  mapk10; mitogen-activated protein kinase 10 isoform X1 [KO:K04440] [EC:2.7.11.24]
119915573  mapk8b; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
119891584  zgc:171775; STKc_p38 domain-containing protein [KO:K04441] [EC:2.7.11.24]
119905572  mapk14a; mitogen-activated protein kinase 14A isoform X1 [KO:K04441] [EC:2.7.11.24]
119918284  mapk11; mitogen-activated protein kinase 11 [KO:K04441] [EC:2.7.11.24]
119906000  mapk13; mitogen-activated protein kinase 13 [KO:K04441] [EC:2.7.11.24]
119918532  mitogen-activated protein kinase 12-like isoform X1 [KO:K04441] [EC:2.7.11.24]
119886184  mapk14b; mitogen-activated protein kinase 14B isoform X1 [KO:K04441] [EC:2.7.11.24]
119915355  mapk12a; mitogen-activated protein kinase 12 [KO:K04441] [EC:2.7.11.24]
119891311  mapkapk5; MAP kinase-activated protein kinase 5 [KO:K04442] [EC:2.7.11.1]
119905857  MAP kinase-activated protein kinase 2-like isoform X1 [KO:K04443] [EC:2.7.11.1]
119885911  mapkapk2a; MAP kinase-activated protein kinase 2 [KO:K04443] [EC:2.7.11.1]
119918257  MAP kinase-activated protein kinase 3-like [KO:K04444] [EC:2.7.11.1]
119885927  MAP kinase-activated protein kinase 2-like isoform X1 [KO:K04444] [EC:2.7.11.1]
119885965  mapkapk3; MAP kinase-activated protein kinase 3 [KO:K04444] [EC:2.7.11.1]
119910207  rps6ka5; ribosomal protein S6 kinase alpha-5 [KO:K04445] [EC:2.7.11.1]
119894762  rps6ka4; LOW QUALITY PROTEIN: ribosomal protein S6 kinase alpha-4 [KO:K16510] [EC:2.7.11.1]
119910142  cdc25b; M-phase inducer phosphatase 2 [KO:K05866] [EC:3.1.3.48]
119897990  nuclear factor of activated T-cells, cytoplasmic 1-like isoform X1 [KO:K04446]
119907292  nfatc1; nuclear factor of activated T-cells, cytoplasmic 1 isoform X1 [KO:K04446]
119889787  nfatc3a; nuclear factor of activated T-cells, cytoplasmic 3 isoform X1 [KO:K17333]
119901002  jun; transcription factor AP-1 isoform X1 [KO:K04448]
119902398  transcription factor AP-1-like [KO:K04448]
119915034  june; junE proto-oncogene, AP-1 transcription factor subunit [KO:K04448]
119900496  transcription factor jun-D-like [KO:K04449]
119902229  jund; transcription factor jun-D [KO:K04449]
119904115  atf2; cyclic AMP-dependent transcription factor ATF-2 [KO:K04450]
119911875  tp53; cellular tumor antigen p53 [KO:K04451]
119886641  ddit3; DNA damage-inducible transcript 3 protein [KO:K04452]
119903309  protein max-like isoform X1 [KO:K04453]
119910476  protein max-like isoform X1 [KO:K04453]
119908498  max; protein max isoform X1 [KO:K04453]
119891760  mef2cb; myocyte enhancer factor 2cb isoform X1 [KO:K04454]
119914508  mef2ca; myocyte enhancer factor 2ca isoform X1 [KO:K04454]
119914382  heat shock protein beta-1-like [KO:K04455]
119895871  hspb1; heat shock protein beta-1 [KO:K04455]
119896812  RAC-gamma serine/threonine-protein kinase-like [KO:K04456] [EC:2.7.11.1]
119910551  akt1; RAC-alpha serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
119882692  akt2; RAC-beta serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
119916983  akt3a; RAC-gamma serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
119898122  akt3b; RAC-gamma serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
119895081  RAC-beta serine/threonine-protein kinase-like [KO:K04456] [EC:2.7.11.1]
119882304  ppm1na; LOW QUALITY PROTEIN: protein phosphatase, Mg2+/Mn2+ dependent, 1Na (putative) [KO:K04457] [EC:3.1.3.16]
119917775  protein phosphatase 1A-like [KO:K04457] [EC:3.1.3.16]
119909977  ppm1aa; protein phosphatase 1A [KO:K04457] [EC:3.1.3.16]
119883764  receptor-type tyrosine-protein phosphatase R-like [KO:K04458] [EC:3.1.3.48]
119895011  ptprr; receptor-type tyrosine-protein phosphatase R [KO:K04458] [EC:3.1.3.48]
119893264  tyrosine-protein phosphatase non-receptor type 5-like [KO:K18018] [EC:3.1.3.48]
119906029  tyrosine-protein phosphatase non-receptor type 7-like [KO:K18019] [EC:3.1.3.48]
119889382  dusp1; dual specificity protein phosphatase 1 [KO:K21278] [EC:3.1.3.16 3.1.3.48]
119882215  dual specificity protein phosphatase 4-like [KO:K04459] [EC:3.1.3.16 3.1.3.48]
119891139  dusp2; dual specificity protein phosphatase 2 [KO:K04459] [EC:3.1.3.16 3.1.3.48]
119905567  dual specificity protein phosphatase 7-like [KO:K04459] [EC:3.1.3.16 3.1.3.48]
119884876  dual specificity protein phosphatase 5-like [KO:K04459] [EC:3.1.3.16 3.1.3.48]
119899414  dusp5; dual specificity protein phosphatase 5 [KO:K04459] [EC:3.1.3.16 3.1.3.48]
119919068  si:ch211-195b15.8; probable dual specificity protein phosphatase DDB_G0281963 [KO:K04459] [EC:3.1.3.16 3.1.3.48]
119893263  dusp8a; LOW QUALITY PROTEIN: dual specificity protein phosphatase 8a [KO:K04459] [EC:3.1.3.16 3.1.3.48]
119885998  dusp7; dual specificity protein phosphatase 7 [KO:K04459] [EC:3.1.3.16 3.1.3.48]
119901576  dusp16; dual specificity protein phosphatase 16 [KO:K04459] [EC:3.1.3.16 3.1.3.48]
119909773  dual specificity protein phosphatase 4-like [KO:K04459] [EC:3.1.3.16 3.1.3.48]
119893643  dusp6; dual specificity protein phosphatase 6 [KO:K21946] [EC:3.1.3.16 3.1.3.48]
119893006  dusp10; dual specificity protein phosphatase 10 [KO:K20216] [EC:3.1.3.16 3.1.3.48]
119882442  dual specificity protein phosphatase 3-like isoform X1 [KO:K17614] [EC:3.1.3.16 3.1.3.48]
119916311  dusp3a; dual specificity protein phosphatase 3 [KO:K17614] [EC:3.1.3.16 3.1.3.48]
119882897  ppp5c; serine/threonine-protein phosphatase 5 [KO:K04460] [EC:3.1.3.16]
119916370  ppm1bb; protein phosphatase 1bb isoform X1 [KO:K04461] [EC:3.1.3.16]
119916874  ppm1ba; protein phosphatase 1B [KO:K04461] [EC:3.1.3.16]
119918819  protein phosphatase 1B-like [KO:K04461] [EC:3.1.3.16]
119896543  heat shock 70 kDa protein 1 [KO:K03283]
119883053  hspa8b; LOW QUALITY PROTEIN: heat shock protein family A (Hsp70) member 8b [KO:K03283]
119898309  hsc70; heat shock cognate 71 kDa protein isoform X1 [KO:K03283]
119905855  hspa1b; heat shock 70 kDa protein 1B [KO:K03283]
119895269  heat shock 70 kDa protein 1-like [KO:K03283]
119895311  heat shock 70 kDa protein 1-like [KO:K03283]
119895319  heat shock 70 kDa protein 1-like [KO:K03283]
119895682  heat shock cognate 71 kDa protein [KO:K03283]
119895688  heat shock cognate 71 kDa protein-like [KO:K03283]
119883057  mecom; histone-lysine N-methyltransferase MECOM isoform X1 [KO:K04462] [EC:2.1.1.367]
119890174  map2k5; dual specificity mitogen-activated protein kinase kinase 5 isoform X1 [KO:K04463] [EC:2.7.12.2]
119915935  mapk7; mitogen-activated protein kinase 7 [KO:K04464] [EC:2.7.11.24]
119906135  nr4a1; nuclear receptor subfamily 4 group A member 1 [KO:K04465]
119886035  probable nuclear hormone receptor HR38 [KO:K04465]
119916377  uncharacterized protein LOC119916377 [KO:K04466] [EC:2.7.11.25]
119891999  map3k14a; mitogen-activated protein kinase kinase kinase 14 [KO:K04466] [EC:2.7.11.25]
119917364  inhibitor of nuclear factor kappa-B kinase subunit alpha-like isoform X1 [KO:K04467] [EC:2.7.11.10]
119915458  inhibitor of nuclear factor kappa-B kinase subunit alpha-like isoform X1 [KO:K04467] [EC:2.7.11.10]
119891193  ikbkb; inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1 [KO:K07209] [EC:2.7.11.10]
119905773  NF-kappa-B essential modulator-like [KO:K07210]
119919380  NF-kappa-B essential modulator-like [KO:K07210]
119883124  nlk2; serine/threonine-protein kinase NLK isoform X1 [KO:K04468] [EC:2.7.11.24]
119895293  nlk1; nemo-like kinase, type 1 [KO:K04468] [EC:2.7.11.24]
119888973  nfkb1; nuclear factor NF-kappa-B p105 subunit isoform X1 [KO:K02580]
119911340  nuclear factor NF-kappa-B p100 subunit-like isoform X1 [KO:K04469]
119911844  rela; transcription factor p65 isoform X1 [KO:K04735]
119882344  relb; transcription factor RelB isoform X1 [KO:K09253]
119916740  transcription factor RelB-like isoform X1 [KO:K09253]
Compound
C00076  Calcium cation
C00165  Diacylglycerol
C00338  Lipopolysaccharide
C00575  3',5'-Cyclic AMP
C01245  D-myo-Inositol 1,4,5-trisphosphate
Reference
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MAP kinases.
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Chem Rev 101:2449-76 (2001)
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MAPK pathways in radiation responses.
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Trk receptors: roles in neuronal signal transduction.
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Annu Rev Biochem 72:609-42 (2003)
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Reference
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Harper SJ, LoGrasso P.
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Signalling for survival and death in neurones: the role of stress-activated kinases, JNK and p38.
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Cell Signal 13:299-310 (2001)
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Reference
PMID:12390245
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Takeda K, Ichijo H
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Neuronal p38 MAPK signalling: an emerging regulator of cell fate and function in the nervous system.
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Genes Cells 7:1099-111 (2002)
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Reference
PMID:14597384
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Yang SH, Sharrocks AD, Whitmarsh AJ.
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Transcriptional regulation by the MAP kinase signaling cascades.
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Gene 320:3-21 (2003)
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Reference
PMID:12566928
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Zhu X, Lee HG, Raina AK, Perry G, Smith MA.
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The role of mitogen-activated protein kinase pathways in Alzheimer's disease.
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Neurosignals 11:270-81 (2002)
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Reference
PMID:12849693
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Cho H, Lee J, Kwak NJ, Lee KH, Rha S, Kim YH, Cho YY, Yang KH, Kim K, Lim Y.
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Silica induces nuclear factor-kappaB activation through TAK1 and NIK in Rat2 cell line.
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Toxicol Lett 143:323-30 (2003)
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Reference
PMID:20602996
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Lemmon MA, Schlessinger J
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Cell signaling by receptor tyrosine kinases.
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Cell 141:1117-34 (2010)
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Reference
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Skaper SD
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The neurotrophin family of neurotrophic factors: an overview.
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Methods Mol Biol 846:1-12 (2012)
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Reference
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Chu WM
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Tumor necrosis factor.
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Cancer Lett 328:222-5 (2013)
DOI:10.1016/j.canlet.2012.10.014
Reference
PMID:22296764
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Newton K, Dixit VM
  Title
Signaling in innate immunity and inflammation.
  Journal
Cold Spring Harb Perspect Biol 4:a006049 (2012)
DOI:10.1101/cshperspect.a006049
Reference
PMID:19483709
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Gaestel M, Kotlyarov A, Kracht M
  Title
Targeting innate immunity protein kinase signalling in inflammation.
  Journal
Nat Rev Drug Discov 8:480-99 (2009)
DOI:10.1038/nrd2829
Reference
PMID:23664135
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Ajibade AA, Wang HY, Wang RF
  Title
Cell type-specific function of TAK1 in innate immune signaling.
  Journal
Trends Immunol 34:307-16 (2013)
DOI:10.1016/j.it.2013.03.007
Reference
PMID:24892271
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Turner MD, Nedjai B, Hurst T, Pennington DJ
  Title
Cytokines and chemokines: At the crossroads of cell signalling and inflammatory disease.
  Journal
Biochim Biophys Acta 1843:2563-2582 (2014)
DOI:10.1016/j.bbamcr.2014.05.014
Related
pathway
msam04070  Phosphatidylinositol signaling system
msam04110  Cell cycle
msam04115  p53 signaling pathway
msam04210  Apoptosis
msam04310  Wnt signaling pathway
KO pathway
ko04010   
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