KEGG   PATHWAY: rno05132
Entry
rno05132                    Pathway                                
Name
Salmonella infection - Rattus norvegicus (rat)
Description
Salmonella infection usually presents as a self-limiting gastroenteritis or the more severe typhoid fever and bacteremia. The common disease-causing Salmonella species in human is a single species, Salmonella enterica, which has numerous serovars.
Following intestinal colonization Salmonella inject effector proteins into the host cells using a type III secretion system (T3SS), T3SS1. Then a small group of effector proteins induce rearrangement of the actin cytoskeleton resulting in membrane ruffles and rapid internalization of the bacteria.The T3SS2 is responsible for translocating effector proteins that direct Salmonella-containing vacuole (SCV) maturation. The majority of the bacteria are known to survive and replicate in SCV.
Class
Human Diseases; Infectious disease: bacterial
Pathway map
rno05132  Salmonella infection
rno05132

Disease
H00111  Typhoid fever
Organism
Rattus norvegicus (rat) [GN:rno]
Gene
100361457  Actg1l1; actin, gamma 1 propeptide-like [KO:K05692]
100361891  Rab5al1; ras-related protein Rab-5A [KO:K07887]
102551431  [KO:K05759]
108349792  Gapdhl2; glyceraldehyde-3-phosphate dehydrogenase-like [KO:K00134] [EC:1.2.1.12]
108352954  Gapdhl3; glyceraldehyde-3-phosphate dehydrogenase-like [KO:K00134] [EC:1.2.1.12]
114495  Map2k6; dual specificity mitogen-activated protein kinase kinase 6 [KO:K04433] [EC:2.7.12.2]
114555  Casp4; caspase 4 [KO:K04394] [EC:3.4.22.57 3.4.22.64]
116484  Txn1; thioredoxin [KO:K03671]
116502  Bak1; bcl-2 homologous antagonist/killer [KO:K14021]
116554  Mapk8; mitogen-activated protein kinase 8 [KO:K04440] [EC:2.7.11.24]
116590  Mapk1; mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
116654  Exoc4; exocyst complex component 4 [KO:K06111]
116659  Dync1i2; cytoplasmic dynein 1 intermediate chain 2 isoform 2 [KO:K10415]
116691  Cyth1; cytohesin-1 [KO:K18441]
116692  Cyth2; cytohesin-2 isoform 1 [KO:K18441]
116693  Cyth3; cytohesin-3 [KO:K18441]
116720  Pik3c2g; phosphatidylinositol 3-kinase C2 domain-containing subunit gamma [KO:K00923] [EC:2.7.1.154]
117273  Rhoa; transforming protein RhoA [KO:K04513]
117550  Kif5b; kinesin-1 heavy chain [KO:K10396] [EC:5.6.1.3]
120096209  [KO:K00134] [EC:1.2.1.12]
120098222  [KO:K05692]
120099910  [KO:K08738]
120101714  [KO:K00134] [EC:1.2.1.12]
134480667  [KO:K00134] [EC:1.2.1.12]
134480898  [KO:K00134] [EC:1.2.1.12]
134483684  [KO:K00134] [EC:1.2.1.12]
134484121  [KO:K00922] [EC:2.7.1.153]
134486952  [KO:K00134] [EC:1.2.1.12]
134487102  [KO:K00134] [EC:1.2.1.12]
140654  Rps3; small ribosomal subunit protein uS3 [KO:K02985]
140734  Dynll2; dynein light chain 2, cytoplasmic [KO:K10418]
161452  Lef1; lymphoid enhancer-binding factor 1 [KO:K04492]
170714  Dynlrb1; dynein light chain roadblock-type 1 [KO:K10419]
170851  Map2k1; dual specificity mitogen-activated protein kinase kinase 1 [KO:K04368] [EC:2.7.12.2]
170911  Pik3ca; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
171041  Klc1; kinesin light chain 1 isoform C [KO:K10407]
171436  Mk1; Mk1 protein [KO:K05759]
171455  Exoc2; exocyst complex component 2 [KO:K17637]
171549  Klc3; kinesin light chain 3 [KO:K10407]
191568  Naip6; NLR family, apoptosis inhibitory protein 6 [KO:K12807]
191572  Ahnak; neuroblast differentiation-associated protein AHNAK isoform 1 [KO:K23934]
192181  Podxl; podocalyxin precursor [KO:K06817]
24185  Akt1; RAC-alpha serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
24224  Bcl2; apoptosis regulator Bcl-2 [KO:K02161]
24383  Gapdh; glyceraldehyde-3-phosphate dehydrogenase [KO:K00134] [EC:1.2.1.12]
24494  Il1b; interleukin-1 beta [KO:K04519]
24498  Il6; interleukin-6 precursor [KO:K05405]
24516  Jun; transcription factor Jun [KO:K04448]
24577  Myc; myc proto-oncogene protein [KO:K04377]
24584  Myl11; myosin regulatory light chain 11 [KO:K12758]
246118  Tubb3; tubulin beta-3 chain [KO:K07375]
246240  Ripk3; receptor-interacting serine/threonine-protein kinase 3 [KO:K08847] [EC:2.7.11.1]
246756  Tradd; tumor necrosis factor receptor type 1-associated DEATH domain protein [KO:K03171]
246775  Tnfsf10; tumor necrosis factor ligand superfamily member 10 [KO:K04721]
24699  Ptprc; receptor-type tyrosine-protein phosphatase C isoform 4 precursor [KO:K06478] [EC:3.1.3.48]
24703  Raf1; RAF proto-oncogene serine/threonine-protein kinase [KO:K04366] [EC:2.7.11.1]
24835  Tnf; tumor necrosis factor [KO:K03156]
24887  Bax; apoptosis regulator BAX [KO:K02159]
25166  Casp1; caspase-1 [KO:K01370] [EC:3.4.22.36]
25233  Akt2; RAC-beta serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
25272  Mapk10; mitogen-activated protein kinase 10 isoform 2 [KO:K04440] [EC:2.7.11.24]
252902  Dync1li1; cytoplasmic dynein 1 light intermediate chain 1 [KO:K10416]
25309  Cycs; cytochrome c, somatic [KO:K08738]
25310  Cyct; cytochrome c, testis-specific [KO:K08738]
25402  Casp3; caspase-3 [KO:K02187] [EC:3.4.22.56]
25493  Nfkbia; NF-kappa-B inhibitor alpha [KO:K04734]
25537  Rock2; rho-associated protein kinase 2 [KO:K17388] [EC:2.7.11.39]
25625  Tnfrsf1a; tumor necrosis factor receptor superfamily member 1A precursor [KO:K03158]
25751  Dnm2; dynamin-2 [KO:K23484]
266610  Fadd; FAS-associated death domain protein [KO:K02373]
282817  Pycard; apoptosis-associated speck-like protein containing a CARD [KO:K12799]
287280  Skp1; S-phase kinase-associated protein 1 [KO:K03094]
287362  Nlrp3; NACHT, LRR and PYD domains-containing protein 3 [KO:K12800]
287398  Map2k4; dual specificity mitogen-activated protein kinase kinase 4 [KO:K04430] [EC:2.7.12.2]
287531  Rilp; rab-interacting lysosomal protein [KO:K13883]
287709  Rab5c; ras-related protein Rab-5C [KO:K07889]
287876  Actg1; actin, cytoplasmic 2 [KO:K05692]
288064  Kpna1; importin subunit alpha-5 [KO:K23940]
288669  Arpc3; actin-related protein 2/3 complex subunit 3 [KO:K05756]
288779  Rab5b; ras-related protein Rab-5B [KO:K07888]
289021  Pik3c2b; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta [KO:K00923] [EC:2.7.1.154]
289312  Acbd3; Golgi resident protein GCP60 [KO:K23935]
289337  Tlr5; toll-like receptor 5 [KO:K10168]
289759  Myl7; myosin regulatory light chain 2, atrial isoform [KO:K12754]
289820  Actr2; actin-related protein 2 [KO:K17260]
290019  Cycsl3; cytochrome c, somatic-like [KO:K08738]
290604  Gapdhl10; glyceraldehyde-3-phosphate dehydrogenase-like [KO:K00134] [EC:1.2.1.12]
290798  Dctn6; dynactin subunit 6 [KO:K10428]
291081  Tubb2b; tubulin beta-2B chain [KO:K07375]
291287  Tubal3; tubulin alpha chain-like 3 [KO:K07374]
29167  Dctn1; dynactin subunit 1 [KO:K04648]
291964  Fhod1; FH1/FH2 domain-containing protein 1 [KO:K23938]
29197  Il18; interleukin-18 [KO:K05482]
29213  Tubb4a; tubulin beta-4A chain [KO:K07375]
29214  Tubb5; tubulin beta-5 chain [KO:K07375]
29260  Tlr4; toll-like receptor 4 precursor [KO:K10160]
29355  Pkn1; serine/threonine-protein kinase N1 [KO:K06071] [EC:2.7.11.13]
293621  Hras; GTPase HRas [KO:K02833]
293860  Flna; filamin-A [KO:K04437]
294010  Actr1a; alpha-centractin [KO:K16575]
29414  Akt3; RAC-gamma serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
29431  Pak1; serine/threonine-protein kinase PAK 1 [KO:K04409] [EC:2.7.11.1]
29433  Pak3; serine/threonine-protein kinase PAK 3 [KO:K05733] [EC:2.7.11.1]
29448  Rab7a; ras-related protein Rab-7a [KO:K07897]
294691  Naip5; baculoviral IAP repeat-containing protein 1f isoform X2 [KO:K12807]
29489  Dync1h1; cytoplasmic dynein 1 heavy chain 1 [KO:K10413]
29513  Mapk13; mitogen-activated protein kinase 13 [KO:K04441] [EC:2.7.11.24]
295423  Gapdhl9; glyceraldehyde-3-phosphate dehydrogenase-like [KO:K00134] [EC:1.2.1.12]
29564  Dync1i1; cytoplasmic dynein 1 intermediate chain 1 [KO:K10415]
296083  Vps18; vacuolar protein sorting-associated protein 18 homolog [KO:K20181]
296159  Vps16; vacuolar protein sorting-associated protein 16 homolog [KO:K20180]
296313  Myl9; myosin regulatory light polypeptide 9 [KO:K12755]
296554  Tubb4b; tubulin beta-4B chain [KO:K07375]
296710  Arpc5l; actin-related protein 2/3 complex subunit 5-like protein [KO:K05754]
297173  RSA-14-44; ras homolog gene family, member A [KO:K04513]
297518  Arpc4; actin-related protein 2/3 complex subunit 4 [KO:K05755]
298767  Dync2li1; cytoplasmic dynein 2 light intermediate chain 1 [KO:K10417]
298784  Nlrc4; NLR family CARD domain-containing protein 4 [KO:K12805]
298947  Pik3cg; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform [KO:K21289] [EC:2.7.1.153]
299121  Actr10; actin-related protein 10 [KO:K16576]
299145  Rhoj; rho-related GTP-binding protein RhoJ [KO:K07864]
299331  Hsp90aa1; heat shock protein HSP 90-alpha [KO:K04079]
299850  Dctn2; dynactin subunit 2 [KO:K10424]
300177  Irak4; interleukin-1 receptor-associated kinase 4 [KO:K04733] [EC:2.7.11.1]
300218  Tuba1c; tubulin alpha-1C chain [KO:K07374]
300724  Fbxo22; F-box only protein 22 [KO:K10302]
301059  Myd88; myeloid differentiation primary response protein MyD88 [KO:K04729]
301085  Fyco1; FYVE and coiled-coil domain-containing protein 1 [KO:K21954]
301252  Hsp90ab1; heat shock protein HSP 90-beta [KO:K04079]
301511  Arpc2; actin-related protein 2/3 complex subunit 2 [KO:K05758]
303200  Map2k3; dual specificity mitogen-activated protein kinase kinase 3 [KO:K04432] [EC:2.7.12.2]
303448  Gapdhl6; similar to glyceraldehyde-3-phosphate dehydrogenase [KO:K00134] [EC:1.2.1.12]
303584  Plekhm1; pleckstrin homology domain-containing family M member 1 [KO:K23282]
305341  Rhoh; rho-related GTP-binding protein RhoH [KO:K07873]
305353  Tlr6; toll-like receptor 6 [KO:K10169]
306886  Ripk1; receptor-interacting serine/threonine-protein kinase 1 [KO:K02861] [EC:2.7.11.1]
306991  Vps41; vacuolar protein sorting-associated protein 41 homolog [KO:K20184]
307351  Tubb6; tubulin beta-6 chain [KO:K07375]
308267  Tab2; TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 [KO:K04404]
308666  Cyfip1; cytoplasmic FMR1-interacting protein 1 [KO:K05749]
308875  Rhog; rho-related GTP-binding protein RhoG [KO:K07863]
308961  Dctn5; dynactin subunit 5 [KO:K10427]
309159  Klc2; kinesin light chain 2 [KO:K10407]
309165  Rela; transcription factor p65 [KO:K04735]
309295  Ikbkg; NF-kappa-B essential modulator [KO:K07210]
309361  Chuk; inhibitor of nuclear factor kappa-B kinase subunit alpha [KO:K04467] [EC:2.7.11.10]
309798  Gcc2; GRIP and coiled-coil domain-containing protein 2 [KO:K20282]
310097  Snx18; sorting nexin-18 [KO:K17923]
310460  Arhgef26; Rho guanine nucleotide exchange factor 26 [KO:K13744]
310553  Tlr2; toll-like receptor 2 precursor [KO:K10159]
311024  Kif5c; kinesin heavy chain isoform 5C [KO:K10396] [EC:5.6.1.3]
311245  Traf6; TNF receptor-associated factor 6 [KO:K03175] [EC:2.3.2.27]
311786  Traf2; TNF receptor-associated factor 2 [KO:K03173] [EC:2.3.2.27]
312451  Tcf7l1; transcription factor 7-like 1 [KO:K04490]
312689  M6pr; cation-dependent mannose-6-phosphate receptor precursor [KO:K10089]
313121  Map3k7; mitogen-activated protein kinase kinase kinase 7 [KO:K04427] [EC:2.7.11.25]
313667  Plekhm2; pleckstrin homology domain-containing family M member 2 [KO:K15348]
314322  Fos; protein c-Fos [KO:K04379]
314478  Ahnak2; protein AHNAK2 isoform X1 [KO:K23934]
314906  Kif5a; kinesin heavy chain isoform 5A [KO:K10396] [EC:5.6.1.3]
315084  Gsdmd; gasdermin-D [KO:K20917]
315139  Tab1; TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 [KO:K04403]
315348  Nckap1l; nck-associated protein 1-like isoform 2 [KO:K05750]
315600  Vps11; vacuolar protein sorting-associated protein 11 homolog [KO:K20179]
315696  Snx33; sorting nexin-33 [KO:K17923]
315840  Myo6; myosin VI [KO:K10358]
316226  Klc4; kinesin light chain 4 [KO:K10407]
316333  Actr1b; beta-centractin [KO:K16575]
316531  Tuba4a; tubulin alpha-4A chain [KO:K07374]
317546  Tab3; TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 isoform X1 [KO:K12793]
338457  Tlr9; toll-like receptor 9 precursor [KO:K10161]
360854  Arpc5; actin-related protein 2/3 complex subunit 5 [KO:K05754]
361055  Kpna3; importin subunit alpha-4 [KO:K23583]
361251  Elmo1; engulfment and cell motility protein 1 [KO:K12366]
361415  Dynlrb2; dynein light chain roadblock-type 2 [KO:K10419]
361568  Rras; ras-related protein R-Ras [KO:K07829]
361632  Pik3c2a; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha [KO:K00923] [EC:2.7.1.154]
361959  Kpna4; importin subunit alpha-3 [KO:K23583]
362199  Vps39; vam6/Vps39-like protein [KO:K20183]
362271  Elmo2; engulfment and cell motility protein 2 [KO:K18985]
362273  Cse1l; exportin-2 [KO:K18423]
362298  Actr3b; actin-related protein 3B [KO:K18584]
362491  Ripk2; receptor-interacting serine/threonine-protein kinase 2 [KO:K08846] [EC:2.7.11.1]
362504  Dctn3; dynactin subunit 3 [KO:K10425]
362862  Hsp90b1; endoplasmin precursor [KO:K09487]
363448  Dynlt3; dynein light chain Tctex-type 3 [KO:K10420]
363520  Irak1; interleukin-1 receptor-associated kinase 1 [KO:K04730] [EC:2.7.11.1]
363595  Tcf7; transcription factor 7 [KO:K02620]
363855  Map2k7; dual specificity mitogen-activated protein kinase kinase 7 isoform 1 [KO:K04431] [EC:2.7.12.2]
363875  Rac1; ras-related C3 botulinum toxin substrate 1 [KO:K04392]
363925  Myl2; myosin regulatory light chain 2, ventricular/cardiac muscle isoform [KO:K10351]
366508  Pik3cd; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform [KO:K00922] [EC:2.7.1.153]
367149  Bax-ps1; apoptosis regulator BAX-like [KO:K02159]
367858  Hrasl1; HRas proto-oncogene, GTPase like 1 [KO:K02833]
367915  Rab9b; ras-related protein Rab-9B [KO:K07900]
448830  Ly96; lymphocyte antigen 96 precursor [KO:K05400]
494222  Pfn4; profilin-4 [KO:K05759]
498234  Arl8a; ADP-ribosylation factor-like protein 8A [KO:K07955]
498736  Tubb2a; tubulin beta-2A chain [KO:K07375]
498977  Dctn3l1; dynactin 3-like 1 [KO:K10425]
499803  Rps3l1; small ribosomal subunit protein uS3-like [KO:K02985]
500133  Nod1; nucleotide-binding oligomerization domain-containing protein 1 [KO:K08727]
500282  Arl8b; ADP-ribosylation factor-like protein 8B [KO:K07955]
500319  Tuba3a; tubulin alpha-3 chain [KO:K07374]
500363  Tuba3b; tubulin alpha-3 chain [KO:K07374]
500377  Tuba8; tubulin alpha-8 chain [KO:K07374]
500906  Cyth4; cytohesin-4 isoform 2 [KO:K18441]
500929  Tuba1b; tubulin alpha-1B chain [KO:K07374]
501203  Myl12a; myosin regulatory light chain RLC-A [KO:K12757]
501831  Myl10; myosin regulatory light chain 10 [KO:K12756]
501854  Rab7b; ras-related protein Rab-7b [KO:K07898]
50658  Mapk9; mitogen-activated protein kinase 9 isoform 2 [KO:K04440] [EC:2.7.11.24]
50685  Myl12b; myosin regulatory light chain 12B [KO:K12757]
50689  Mapk3; mitogen-activated protein kinase 3 [KO:K04371] [EC:2.7.11.24]
54227  Arpc1b; actin-related protein 2/3 complex subunit 1B [KO:K05757]
56611  Anxa2; annexin A2 [KO:K17092]
58823  Nckap1; nck-associated protein 1 [KO:K05750]
58945  Dynll1; dynein light chain 1, cytoplasmic [KO:K10418]
58960  Map2k2; dual specificity mitogen-activated protein kinase kinase 2 [KO:K04369] [EC:2.7.12.2]
60350  Cd14; monocyte differentiation antigen CD14 precursor [KO:K04391]
60352  Mapk12; mitogen-activated protein kinase 12 [KO:K04441] [EC:2.7.11.24]
60371  Birc2; baculoviral IAP repeat-containing protein 2 [KO:K16060]
60627  Exoc5; exocyst complex component 5 [KO:K19984]
64026  Casp7; caspase-7 [KO:K04397] [EC:3.4.22.60]
64044  Casp8; caspase-8 [KO:K04398] [EC:3.4.22.61]
64158  Tuba1a; tubulin alpha-1A chain [KO:K07374]
64303  Pfn1; profilin-1 [KO:K05759]
64310  Arf1; ADP-ribosylation factor 1 [KO:K07937]
64373  Rhob; rho-related GTP-binding protein RhoB [KO:K07856]
64465  Cdc42; cell division control protein 42 homolog [KO:K04393]
64632  Exoc7; exocyst complex component 7 [KO:K07195]
64633  Rab5a; ras-related protein Rab-5A [KO:K07887]
65052  Pik3c3; phosphatidylinositol 3-kinase catalytic subunit type 3 [KO:K00914] [EC:2.7.1.137]
65081  Vps33a; vacuolar protein sorting-associated protein 33A [KO:K20182]
65209  Dync2h1; cytoplasmic dynein 2 heavy chain 1 [KO:K10414]
679312  Tubb1; tubulin beta-1 chain isoform X1 [KO:K07375]
679794  Cycsl1; cytochrome c, somatic-like [KO:K08738]
679869  Tcf7l2; transcription factor 7-like 2 [KO:K04491]
679934  Brk1; protein BRICK1 [KO:K05752]
680127  Tirap; toll/interleukin-1 receptor domain-containing adapter protein [KO:K05403]
681314  [KO:K02159]
682507  Wasl; actin nucleation-promoting factor WASL [KO:K23612]
682937  Wasf3; WASP family member 3 [KO:K06083]
683687  Snx9; sorting nexin-9 [KO:K17923]
685936  Pfn3; profilin-3 [KO:K05759]
689314  Mapk11; mitogen-activated protein kinase 11 [KO:K04441] [EC:2.7.11.24]
690675  Cycsl2; cytochrome c, somatic-like [KO:K08738]
690743  Mlkl; mixed lineage kinase domain-like protein [KO:K08849] [EC:2.7.11.1]
78971  Birc3; baculoviral IAP repeat-containing protein 3 [KO:K16060]
79119  Arf2; ADP-ribosylation factor 2 [KO:K07937]
79121  Arf6; ADP-ribosylation factor 6 [KO:K07941]
79249  Abi1; abl interactor 1 [KO:K23649]
79462  Txn2; thioredoxin, mitochondrial precursor [KO:K03671]
81531  Pfn2; profilin-2 [KO:K05759]
81649  Mapk14; mitogen-activated protein kinase 14 [KO:K04441] [EC:2.7.11.24]
81655  Dync1li2; cytoplasmic dynein 1 light intermediate chain 2 isoform 2 [KO:K10416]
81732  Actr3; actin-related protein 3 [KO:K18584]
81736  Nfkb1; nuclear factor NF-kappa-B p105 subunit isoform 2 [KO:K02580]
81757  Rala; ras-related protein Ral-A [KO:K07834]
81778  S100a10; protein S100-A10 [KO:K17274]
81822  Actb; actin, cytoplasmic 1 [KO:K05692]
81824  Arpc1a; actin-related protein 2/3 complex subunit 1A [KO:K05757]
83462  Dynlt1; dynein light chain Tctex-type 1 [KO:K10420]
84351  Ikbkb; inhibitor of nuclear factor kappa-B kinase subunit beta [KO:K07209] [EC:2.7.11.10]
84353  Ctnnb1; catenin beta-1 [KO:K02105]
84428  Dctn4; dynactin subunit 4 [KO:K10426]
84589  Rab9a; ras-related protein Rab-9A [KO:K07899]
85243  Pik3cb; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
Compound
C00338  Lipopolysaccharide
C01194  1-Phosphatidyl-D-myo-inositol
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C11554  1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
Reference
PMID:28875943
  Authors
Bernal-Bayard J, Ramos-Morales F
  Title
Molecular Mechanisms Used by Salmonella to Evade the Immune System.
  Journal
Curr Issues Mol Biol 25:133-168 (2018)
DOI:10.21775/cimb.025.133
Reference
PMID:28848711
  Authors
Hume PJ, Singh V, Davidson AC, Koronakis V
  Title
Swiss Army Pathogen: The Salmonella Entry Toolkit.
  Journal
Front Cell Infect Microbiol 7:348 (2017)
DOI:10.3389/fcimb.2017.00348
Reference
PMID:31402916
  Authors
Wemyss MA, Pearson JS
  Title
Host Cell Death Responses to Non-typhoidal Salmonella Infection.
  Journal
Front Immunol 10:1758 (2019)
DOI:10.3389/fimmu.2019.01758
Reference
PMID:27974148
  Authors
Bierschenk D, Boucher D, Schroder K
  Title
Salmonella-induced inflammasome activation in humans.
  Journal
Mol Immunol 86:38-43 (2017)
DOI:10.1016/j.molimm.2016.11.009
Reference
PMID:29477730
  Authors
Pinaud L, Sansonetti PJ, Phalipon A
  Title
Host Cell Targeting by Enteropathogenic Bacteria T3SS Effectors.
  Journal
Trends Microbiol 26:266-283 (2018)
DOI:10.1016/j.tim.2018.01.010
Reference
PMID:25749450
  Authors
LaRock DL, Chaudhary A, Miller SI
  Title
Salmonellae interactions with host processes.
  Journal
Nat Rev Microbiol 13:191-205 (2015)
DOI:10.1038/nrmicro3420
Reference
PMID:17983751
  Authors
Ramsden AE, Holden DW, Mota LJ
  Title
Membrane dynamics and spatial distribution of Salmonella-containing vacuoles.
  Journal
Trends Microbiol 15:516-24 (2007)
DOI:10.1016/j.tim.2007.10.002
Reference
PMID:22702524
  Authors
van der Heijden J, Finlay BB
  Title
Type III effector-mediated processes in Salmonella infection.
  Journal
Future Microbiol 7:685-703 (2012)
DOI:10.2217/fmb.12.49
Reference
PMID:27222578
  Authors
Galan JE
  Title
Typhoid toxin provides a window into typhoid fever and the biology of Salmonella Typhi.
  Journal
Proc Natl Acad Sci U S A 113:6338-44 (2016)
DOI:10.1073/pnas.1606335113
Reference
PMID:19157959
  Authors
McGhie EJ, Brawn LC, Hume PJ, Humphreys D, Koronakis V
  Title
Salmonella takes control: effector-driven manipulation of the host.
  Journal
Curr Opin Microbiol 12:117-24 (2009)
DOI:10.1016/j.mib.2008.12.001
Reference
PMID:12675800
  Authors
Miao EA, Brittnacher M, Haraga A, Jeng RL, Welch MD, Miller SI
  Title
Salmonella effectors translocated across the vacuolar membrane interact with the actin cytoskeleton.
  Journal
Mol Microbiol 48:401-15 (2003)
DOI:10.1046/j.1365-2958.2003.t01-1-03456.x
Reference
PMID:17074883
  Authors
Patel JC, Galan JE
  Title
Differential activation and function of Rho GTPases during Salmonella-host cell interactions.
  Journal
J Cell Biol 175:453-63 (2006)
DOI:10.1083/jcb.200605144
Reference
PMID:18411289
  Authors
Wasylnka JA, Bakowski MA, Szeto J, Ohlson MB, Trimble WS, Miller SI, Brumell JH
  Title
Role for myosin II in regulating positioning of Salmonella-containing vacuoles and intracellular replication.
  Journal
Infect Immun 76:2722-35 (2008)
DOI:10.1128/IAI.00152-08
Reference
PMID:10499590
  Authors
Fu Y, Galan JE
  Title
A salmonella protein antagonizes Rac-1 and Cdc42 to mediate host-cell recovery after bacterial invasion.
  Journal
Nature 401:293-7 (1999)
DOI:10.1038/45829
Related
pathway
rno04010  MAPK signaling pathway
rno04064  NF-kappa B signaling pathway
rno04210  Apoptosis
rno04217  Necroptosis
rno04621  NOD-like receptor signaling pathway
KO pathway
ko05132   

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