KEGG   PATHWAY: oke04010
Entry
oke04010                    Pathway                                
Name
MAPK signaling pathway - Oncorhynchus keta (chum salmon)
Description
The mitogen-activated protein kinase (MAPK) cascade is a highly conserved module that is involved in various cellular functions, including cell proliferation, differentiation and migration. Mammals express at least four distinctly regulated groups of MAPKs, extracellular signal-related kinases (ERK)-1/2, Jun amino-terminal kinases (JNK1/2/3), p38 proteins (p38alpha/beta/gamma/delta) and ERK5, that are activated by specific MAPKKs: MEK1/2 for ERK1/2, MKK3/6 for the p38, MKK4/7 (JNKK1/2) for the JNKs, and MEK5 for ERK5. Each MAPKK, however, can be activated by more than one MAPKKK, increasing the complexity and diversity of MAPK signalling. Presumably each MAPKKK confers responsiveness to distinct stimuli. For example, activation of ERK1/2 by growth factors depends on the MAPKKK c-Raf, but other MAPKKKs may activate ERK1/2 in response to pro-inflammatory stimuli.
Class
Environmental Information Processing; Signal transduction
Pathway map
oke04010  MAPK signaling pathway
oke04010

Other DBs
GO: 0000165
Organism
Oncorhynchus keta (chum salmon) [GN:oke]
Gene
118374962  LOW QUALITY PROTEIN: voltage-dependent P/Q-type calcium channel subunit alpha-1A-like [KO:K04344]
118375936  voltage-dependent P/Q-type calcium channel subunit alpha-1A-like isoform X1 [KO:K04344]
118394045  voltage-dependent N-type calcium channel subunit alpha-1B-like [KO:K04849]
118385587  voltage-dependent N-type calcium channel subunit alpha-1B-like [KO:K04849]
118388078  voltage-dependent N-type calcium channel subunit alpha-1B-like isoform X1 [KO:K04849]
118357836  voltage-dependent N-type calcium channel subunit alpha-1B-like isoform X1 [KO:K04849]
127925063  cacna1c; voltage-dependent L-type calcium channel subunit alpha-1C isoform X1 [KO:K04850]
118377279  voltage-dependent L-type calcium channel subunit alpha-1D-like isoform X1 [KO:K04851]
118361111  voltage-dependent L-type calcium channel subunit alpha-1D-like isoform X1 [KO:K04851]
118372828  voltage-dependent L-type calcium channel subunit alpha-1D isoform X1 [KO:K04851]
118395224  voltage-dependent R-type calcium channel subunit alpha-1E-like [KO:K04852]
118391197  voltage-dependent R-type calcium channel subunit alpha-1E isoform X2 [KO:K04852]
118359124  voltage-dependent R-type calcium channel subunit alpha-1E-like [KO:K04852]
118401978  voltage-dependent R-type calcium channel subunit alpha-1E-like isoform X1 [KO:K04852]
118359894  voltage-dependent L-type calcium channel subunit alpha-1F-like [KO:K04853]
118360554  voltage-dependent L-type calcium channel subunit alpha-1D-like [KO:K04853]
118379413  cacna1fb; calcium channel, voltage-dependent, L type, alpha 1F subunit [KO:K04853]
118357736  cacna1g; LOW QUALITY PROTEIN: voltage-dependent T-type calcium channel subunit alpha-1G [KO:K04854]
127925623  LOW QUALITY PROTEIN: voltage-dependent T-type calcium channel subunit alpha-1I-like [KO:K04855]
127925625  LOW QUALITY PROTEIN: voltage-dependent T-type calcium channel subunit alpha-1I-like [KO:K04855]
118382482  voltage-dependent T-type calcium channel subunit alpha-1I-like [KO:K04856]
118381309  voltage-dependent T-type calcium channel subunit alpha-1I-like [KO:K04856]
118360125  dihydropyridine-sensitive L-type skeletal muscle calcium channel subunit alpha-1-like isoform X1 [KO:K04857]
118389361  dihydropyridine-sensitive L-type skeletal muscle calcium channel subunit alpha-1-like [KO:K04857]
118399696  dihydropyridine-sensitive L-type skeletal muscle calcium channel subunit alpha-1-like [KO:K04857]
118401180  LOW QUALITY PROTEIN: voltage-dependent calcium channel subunit alpha-2/delta-1 [KO:K04858]
118396257  voltage-dependent calcium channel subunit alpha-2/delta-1-like isoform X1 [KO:K04858]
118388289  voltage-dependent calcium channel subunit alpha-2/delta-2-like isoform X1 [KO:K04859]
118389044  LOW QUALITY PROTEIN: voltage-dependent calcium channel subunit alpha-2/delta-2-like [KO:K04859]
118399834  voltage-dependent calcium channel subunit alpha-2/delta-2-like isoform X1 [KO:K04859]
118380031  cacna2d3a; voltage-dependent calcium channel subunit alpha-2/delta-3 [KO:K04860]
118372827  voltage-dependent calcium channel subunit alpha-2/delta-3 [KO:K04860]
118374132  voltage-dependent calcium channel subunit alpha-2/delta-3-like [KO:K04860]
118358776  voltage-dependent calcium channel subunit alpha-2/delta-4-like isoform X1 [KO:K04861]
127925440  voltage-dependent calcium channel subunit alpha-2/delta-4-like [KO:K04861]
118396491  voltage-dependent calcium channel subunit alpha-2/delta-4-like [KO:K04861]
118365240  voltage-dependent L-type calcium channel subunit beta-1 isoform X1 [KO:K04862]
118361508  voltage-dependent L-type calcium channel subunit beta-2-like isoform X1 [KO:K04863]
118373708  cacnb2a; voltage-dependent L-type calcium channel subunit beta-2a isoform X1 [KO:K04863]
118360140  voltage-dependent L-type calcium channel subunit beta-4 isoform X2 [KO:K04864]
118360441  cacnb3a; voltage-dependent L-type calcium channel subunit beta-3a [KO:K04864]
118372730  voltage-dependent L-type calcium channel subunit beta-4-like [KO:K04864]
118386349  voltage-dependent L-type calcium channel subunit beta-4-like isoform X1 [KO:K04865]
118379658  voltage-dependent L-type calcium channel subunit beta-4-like [KO:K04865]
118366917  voltage-dependent L-type calcium channel subunit beta-4 isoform X1 [KO:K04865]
118370366  voltage-dependent calcium channel gamma-1 subunit-like [KO:K04866]
118364981  voltage-dependent calcium channel gamma-1 subunit-like [KO:K04866]
118389192  voltage-dependent calcium channel gamma-1 subunit-like [KO:K04866]
127920539  voltage-dependent calcium channel gamma-1 subunit-like [KO:K04866]
118365651  voltage-dependent calcium channel gamma-2 subunit-like [KO:K04867]
118371515  voltage-dependent calcium channel gamma-2 subunit [KO:K04867]
127932393  voltage-dependent calcium channel gamma-2 subunit-like [KO:K04867]
127926083  voltage-dependent calcium channel gamma-3 subunit-like [KO:K04868]
127921868  voltage-dependent calcium channel gamma-3 subunit-like [KO:K04868]
118380888  cacng4b; calcium channel, voltage-dependent, gamma subunit 4b [KO:K04869]
118364709  voltage-dependent calcium channel gamma-4 subunit-like [KO:K04869]
118389580  voltage-dependent calcium channel gamma-4 subunit-like isoform X1 [KO:K04869]
118371475  voltage-dependent calcium channel gamma-5 subunit-like isoform X1 [KO:K04870]
118382274  cacng5b; voltage-dependent calcium channel gamma-5 subunit isoform X1 [KO:K04870]
118364708  voltage-dependent calcium channel gamma-5 subunit [KO:K04870]
118363017  voltage-dependent calcium channel gamma-6 subunit-like [KO:K04871]
118398226  voltage-dependent calcium channel gamma-6 subunit-like [KO:K04871]
118399042  voltage-dependent calcium channel gamma-6 subunit-like [KO:K04871]
118380954  voltage-dependent calcium channel gamma-7 subunit-like [KO:K04872]
127915258  voltage-dependent calcium channel gamma-7 subunit-like [KO:K04872]
118398227  voltage-dependent calcium channel gamma-7 subunit-like [KO:K04872]
118399269  voltage-dependent calcium channel gamma-7 subunit-like [KO:K04872]
118361861  voltage-dependent calcium channel gamma-4 subunit-like [KO:K04873]
118374043  voltage-dependent calcium channel gamma-4 subunit-like [KO:K04873]
118397756  voltage-dependent calcium channel gamma-4 subunit-like [KO:K04873]
118399270  voltage-dependent calcium channel gamma-4 subunit-like isoform X1 [KO:K04873]
118401987  cAMP-dependent protein kinase catalytic subunit beta isoform X1 [KO:K04345] [EC:2.7.11.11]
118386773  prkacba; protein kinase, cAMP-dependent, catalytic, beta a isoform X1 [KO:K04345] [EC:2.7.11.11]
118394782  prkacbb; protein kinase, cAMP-dependent, catalytic, beta b [KO:K04345] [EC:2.7.11.11]
118374464  prkacaa; protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a [KO:K04345] [EC:2.7.11.11]
118384731  cAMP-dependent protein kinase catalytic subunit alpha [KO:K04345] [EC:2.7.11.11]
118381223  cAMP-dependent protein kinase catalytic subunit alpha-like [KO:K04345] [EC:2.7.11.11]
127928727  protein kinase C alpha type-like isoform X1 [KO:K02677] [EC:2.7.11.13]
118364978  protein kinase C alpha type [KO:K02677] [EC:2.7.11.13]
118371476  protein kinase C alpha type isoform X1 [KO:K02677] [EC:2.7.11.13]
127929301  protein kinase C beta type-like [KO:K19662] [EC:2.7.11.13]
127921846  LOW QUALITY PROTEIN: protein kinase C beta type-like [KO:K19662] [EC:2.7.11.13]
127914344  protein kinase C alpha type-like [KO:K19663] [EC:2.7.11.13]
118379399  protein kinase C alpha type-like [KO:K19663] [EC:2.7.11.13]
127921912  LOW QUALITY PROTEIN: guanine nucleotide-binding protein subunit alpha-12-like [KO:K04346]
118393174  gng12b; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 [KO:K04347]
118402392  gng12a; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12a [KO:K04347]
118394491  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12-like [KO:K04347]
118374835  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12-like [KO:K04347]
118358986  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12-like [KO:K04347]
118368726  protein phosphatase 3 catalytic subunit alpha isoform X1 [KO:K04348] [EC:3.1.3.16]
118393418  serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform-like isoform X1 [KO:K04348] [EC:3.1.3.16]
118373527  ppp3cb; serine/threonine-protein phosphatase 2B catalytic subunit beta isoform isoform X1 [KO:K04348] [EC:3.1.3.16]
118391463  serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform-like isoform X1 [KO:K04348] [EC:3.1.3.16]
118377937  protein phosphatase 3 catalytic subunit alpha-like isoform X1 [KO:K04348] [EC:3.1.3.16]
118387772  protein phosphatase 3 catalytic subunit alpha isoform X1 [KO:K04348] [EC:3.1.3.16]
118390486  ppp3ca; serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X1 [KO:K04348] [EC:3.1.3.16]
118358498  serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform-like isoform X1 [KO:K04348] [EC:3.1.3.16]
118391962  protein phosphatase 3 catalytic subunit alpha isoform X3 [KO:K04348] [EC:3.1.3.16]
118382807  calcineurin subunit B type 1 isoform X1 [KO:K06268]
118389158  calcineurin subunit B type 1 isoform X1 [KO:K06268]
118368823  ppp3r1a; calcineurin subunit B type 1 [KO:K06268]
118376159  calcineurin subunit B type 1-like isoform X1 [KO:K06268]
127911337  calcineurin subunit B type 1-like isoform X1 [KO:K06268]
118401210  ras-specific guanine nucleotide-releasing factor 1-like [KO:K04349]
118396738  rasgrf1; ras-specific guanine nucleotide-releasing factor 1 [KO:K04349]
118393568  rasgrf2b; ras-specific guanine nucleotide-releasing factor 2 [KO:K12326]
118388121  ras-specific guanine nucleotide-releasing factor 2-like isoform X1 [KO:K12326]
118362474  RAS guanyl-releasing protein 1-like [KO:K04350]
118368321  LOW QUALITY PROTEIN: RAS guanyl-releasing protein 1-like [KO:K04350]
118381424  rasgrp4; LOW QUALITY PROTEIN: RAS guanyl-releasing protein 4 [KO:K04350]
118368668  RAS guanyl-releasing protein 2-like isoform X3 [KO:K12361]
118384993  rasgrp2; RAS guanyl-releasing protein 2 [KO:K12361]
118392700  RAS guanyl-releasing protein 2-like isoform X1 [KO:K12361]
118369668  rasgrp3; ras guanyl-releasing protein 3 [KO:K12362]
118400476  ras guanyl-releasing protein 3-like [KO:K12362]
118375339  rap guanine nucleotide exchange factor 2-like isoform X1 [KO:K08018]
118363598  rap guanine nucleotide exchange factor 2 isoform X1 [KO:K08018]
118394968  neurofibromin-like isoform X1 [KO:K08052]
118375292  neurofibromin-like isoform X1 [KO:K08052]
127908714  neurofibromin-like [KO:K08052]
118390277  nf1b; neurofibromin isoform X1 [KO:K08052]
118391349  neurofibromin-like [KO:K08052]
118373138  ras GTPase-activating protein 1-like isoform X1 [KO:K04352]
118358029  ras GTPase-activating protein 1-like isoform X1 [KO:K04352]
118397315  ras GTPase-activating protein 2-like isoform X1 [KO:K08053]
118383491  ras GTPase-activating protein 2-like isoform X1 [KO:K08053]
118359921  ras-related protein Rap-1b [KO:K04353]
118360805  ras-related protein Rap-1A-like [KO:K04353]
118388258  ras-related protein Rap-1A-like [KO:K04353]
118399980  ras-related protein Rap-1A-like [KO:K04353]
127927760  ras-related protein Rap-1b-like [KO:K07836]
127927765  ras-related protein Rap-1b [KO:K07836]
118363115  egf; pro-epidermal growth factor [KO:K04357]
118388782  protransforming growth factor alpha-like [KO:K08774]
118400480  protransforming growth factor alpha-like [KO:K08774]
118381988  LOW QUALITY PROTEIN: proepiregulin-like [KO:K09784]
118389805  putative fibroblast growth factor 1 [KO:K18496]
118381612  putative fibroblast growth factor 1 isoform X1 [KO:K18496]
118363560  fgf2; fibroblast growth factor 2 [KO:K18497]
118378991  fibroblast growth factor 2-like isoform X1 [KO:K18497]
118358680  fibroblast growth factor 10-like [KO:K04358]
127925505  fibroblast growth factor 20-like [KO:K04358]
118369630  fgf8a; fibroblast growth factor 8 isoform X1 [KO:K04358]
118385979  fibroblast growth factor 18-like isoform X1 [KO:K04358]
118393709  fgf3; fibroblast growth factor 3 isoform X5 [KO:K04358]
118393710  fibroblast growth factor 4B-like isoform X1 [KO:K04358]
118393996  fgf7; fibroblast growth factor 7 isoform X1 [KO:K04358]
118391710  LOW QUALITY PROTEIN: fibroblast growth factor 18-like [KO:K04358]
118378547  fgf16; fibroblast growth factor 16 [KO:K04358]
118362739  fibroblast growth factor 3-like [KO:K04358]
118387750  fgf10a; fibroblast growth factor 10a [KO:K04358]
118395857  fibroblast growth factor 6-like [KO:K04358]
118363289  fgf20b; fibroblast growth factor 20b [KO:K04358]
118363399  fibroblast growth factor 18-like isoform X1 [KO:K04358]
118363564  fibroblast growth factor 18-like isoform X1 [KO:K04358]
118394095  fibroblast growth factor 10-like [KO:K04358]
127907404  fibroblast growth factor 5-like [KO:K04358]
118366486  fgf9; fibroblast growth factor 4A [KO:K04358]
118375643  fgf17; fibroblast growth factor 17 [KO:K04358]
118397824  fibroblast growth factor 3-like [KO:K04358]
118397825  fibroblast growth factor 4B-like [KO:K04358]
118376501  fibroblast growth factor 8-like isoform X1 [KO:K04358]
118366322  fibroblast growth factor 4B-like [KO:K04358]
118389414  fgf8b; fibroblast growth factor 8b [KO:K04358]
118389455  fibroblast growth factor 10-like [KO:K04358]
118358164  fibroblast growth factor 4B-like [KO:K04358]
118358177  fibroblast growth factor 17-like isoform X1 [KO:K04358]
118379041  fibroblast growth factor 5 [KO:K04358]
118379077  fgf24; fibroblast growth factor 24 isoform X1 [KO:K04358]
118380498  fibroblast growth factor 20 [KO:K04358]
118377190  fibroblast growth factor 8b-like [KO:K04358]
118391723  fibroblast growth factor 10-like [KO:K04358]
118392459  fibroblast growth factor 4B-like [KO:K04358]
118400946  fibroblast growth factor 3-like [KO:K04358]
118400947  fibroblast growth factor 4B-like [KO:K04358]
118401042  fibroblast growth factor 6-like [KO:K04358]
118357881  fibroblast growth factor 5-like [KO:K04358]
118381936  fgf18a; fibroblast growth factor 18a isoform X1 [KO:K04358]
118394297  fgf19; fibroblast growth factor 19 [KO:K22603]
118363311  fgf21; fibroblast growth factor 21 [KO:K22429]
118395856  fibroblast growth factor 23-like [KO:K22428]
118365891  fibroblast growth factor 23-like [KO:K22428]
118392458  fibroblast growth factor 23-like [KO:K22428]
118401041  fibroblast growth factor 23-like [KO:K22428]
127912331  neurotrophin-7-like [KO:K02582]
127912332  LOW QUALITY PROTEIN: neurotrophin-7-like [KO:K02582]
127913048  ngfa; neurotrophin-7 [KO:K02582]
118389443  nerve growth factor-like [KO:K02582]
118399735  ngfb; nerve growth factor [KO:K02582]
118379730  LOW QUALITY PROTEIN: neurotrophin-7-like [KO:K02582]
118393975  brain-derived neurotrophic factor [KO:K04355]
118362595  brain-derived neurotrophic factor-like isoform X2 [KO:K04355]
118383328  neurotrophin-3 [KO:K04356]
127924284  neurotrophin-3-like [KO:K04356]
127913761  insulin-like [KO:K04526]
118390715  insulin-like [KO:K04526]
118391666  insulin [KO:K04526]
118366328  insulin-like growth factor I isoform X1 [KO:K05459]
118392473  insulin-like growth factor I isoform X1 [KO:K05459]
118396286  igf2b; insulin-like growth factor 2b [KO:K13769]
118382497  platelet-derived growth factor subunit A-like [KO:K04359]
127931935  platelet-derived growth factor subunit A-like [KO:K04359]
118382184  platelet-derived growth factor subunit A-like isoform X1 [KO:K04359]
127929712  si:ch211-79m20.1; LOW QUALITY PROTEIN: involucrin [KO:K17386]
118363593  platelet-derived growth factor C-like isoform X1 [KO:K05450]
118373507  platelet-derived growth factor D-like [KO:K05450]
118379632  platelet-derived growth factor C-like [KO:K05450]
118394494  pdgfd; platelet-derived growth factor D isoform X1 [KO:K05450]
118388828  uncharacterized protein LOC118388828 isoform X1 [KO:K05453]
118400500  csf1a; macrophage colony-stimulating factor 1a isoform X1 [KO:K05453]
118395956  kitlga; kit ligand a [KO:K05461]
118365893  uncharacterized protein LOC118365893 [KO:K05461]
118400963  kit ligand-like [KO:K05461]
118386986  vegfab; vascular endothelial growth factor Ab isoform X1 [KO:K05448]
118363266  vascular endothelial growth factor A-like [KO:K05448]
118364172  vascular endothelial growth factor A-A-like isoform X2 [KO:K05448]
118398575  vascular endothelial growth factor A-A-like isoform X1 [KO:K05448]
118367252  vascular endothelial growth factor A-A isoform X1 [KO:K05448]
118381165  vascular endothelial growth factor A [KO:K05448]
118362518  placenta growth factor-like [KO:K16859]
118398429  vascular endothelial growth factor A-like isoform X1 [KO:K16859]
118368282  placenta growth factor-like [KO:K16859]
118363022  vascular endothelial growth factor C-like isoform X1 [KO:K05449]
118395490  vascular endothelial growth factor C-like [KO:K05449]
118390548  vascular endothelial growth factor C-like [KO:K05449]
127916815  LOW QUALITY PROTEIN: vascular endothelial growth factor D-like [KO:K05449]
127916818  vascular endothelial growth factor D-like [KO:K05449]
118384943  vascular endothelial growth factor C-like isoform X1 [KO:K05449]
118401177  hepatocyte growth factor [KO:K05460]
118396152  hepatocyte growth factor-like [KO:K05460]
118377125  hgfa; hepatocyte growth factor a [KO:K05460]
118381973  angiopoietin-1-like [KO:K05465]
118398282  angiopoietin-1-like isoform X1 [KO:K05465]
118399206  angiopoietin-1-like isoform X1 [KO:K05465]
118402754  angiopoietin-2-like [KO:K05466]
118398292  angiopoietin-2-like [KO:K05466]
127909123  angpt2b; angiopoietin-2b [KO:K05466]
118385337  ephrin-A5-like isoform X1 [KO:K05462]
118382269  ephrin-A3-like [KO:K05462]
118394103  ephrin-A5b-like isoform X1 [KO:K05462]
127928113  ephrin-A3-like [KO:K05462]
118379472  ephrin-A1-like [KO:K05462]
118387500  ephrin-A5-like isoform X1 [KO:K05462]
127914047  ephrin-A2-like [KO:K05462]
118377353  si:dkey-246i14.3; ephrin-A4 isoform X1 [KO:K05462]
118398357  ephrin-A3-like isoform X1 [KO:K05462]
127932291  ephrin-A2-like [KO:K05462]
118399103  ephrin-A3-like isoform X1 [KO:K05462]
118399104  ephrin-A1-like [KO:K05462]
127916726  ephrin-A2-like [KO:K05462]
118379060  ephrin-A1-like [KO:K05462]
118358541  ephrin-A5 isoform X1 [KO:K05462]
118380130  ephrin-A2-like [KO:K05462]
118394128  gdnfb; glial cell line-derived neurotrophic factor [KO:K05452]
118387712  gdnfa; glial cell line-derived neurotrophic factor [KO:K05452]
118391716  glial cell line-derived neurotrophic factor-like [KO:K05452]
118401404  neurturin-like [KO:K25414]
118388977  neurturin-like isoform X2 [KO:K25414]
118378601  neurturin-like [KO:K25414]
118402395  artemin-like [KO:K25415]
118395184  artemin [KO:K25415]
118393229  neurturin isoform X1 [KO:K25415]
127932365  persephin [KO:K25416]
118361762  melanoma receptor tyrosine-protein kinase-like isoform X1 [KO:K04361] [EC:2.7.10.1]
118370654  melanoma receptor tyrosine-protein kinase-like [KO:K04361] [EC:2.7.10.1]
118394834  epidermal growth factor receptor-like isoform X1 [KO:K04361] [EC:2.7.10.1]
118401938  epidermal growth factor receptor-like [KO:K04361] [EC:2.7.10.1]
118364277  erbb2; receptor tyrosine-protein kinase erbB-2 [KO:K05083] [EC:2.7.10.1]
118360338  receptor tyrosine-protein kinase erbB-3-like [KO:K05084] [EC:2.7.10.1]
118360519  LOW QUALITY PROTEIN: receptor tyrosine-protein kinase erbB-3-like [KO:K05084] [EC:2.7.10.1]
118388575  receptor tyrosine-protein kinase erbB-3-like isoform X1 [KO:K05084] [EC:2.7.10.1]
118400304  receptor tyrosine-protein kinase erbB-3-like [KO:K05084] [EC:2.7.10.1]
118366646  receptor tyrosine-protein kinase erbB-4-like isoform X1 [KO:K05085] [EC:2.7.10.1]
118386327  receptor tyrosine-protein kinase erbB-4-like isoform X1 [KO:K05085] [EC:2.7.10.1]
127916785  receptor tyrosine-protein kinase erbB-4-like isoform X1 [KO:K05085] [EC:2.7.10.1]
118393173  fibroblast growth factor receptor 1-A-like isoform X1 [KO:K04362] [EC:2.7.10.1]
118385446  fgfr1b; fibroblast growth factor receptor 1b isoform X1 [KO:K04362] [EC:2.7.10.1]
118374923  fibroblast growth factor receptor 1-A-like isoform X1 [KO:K04362] [EC:2.7.10.1]
118358309  fgfr1a; fibroblast growth factor receptor 1-A isoform X1 [KO:K04362] [EC:2.7.10.1]
118363645  fibroblast growth factor receptor 2-like isoform X1 [KO:K05093] [EC:2.7.10.1]
118369377  fibroblast growth factor receptor 2-like isoform X1 [KO:K05093] [EC:2.7.10.1]
118369015  fgfr3; LOW QUALITY PROTEIN: fibroblast growth factor receptor 3 [KO:K05094] [EC:2.7.10.1]
118390046  fibroblast growth factor receptor 4-like [KO:K05095] [EC:2.7.10.1]
118391122  fibroblast growth factor receptor 4 [KO:K05095] [EC:2.7.10.1]
118375905  tumor necrosis factor receptor superfamily member 16-like [KO:K02583]
118370909  tumor necrosis factor receptor superfamily member 16 [KO:K02583]
118364413  ngfrb; nerve growth factor receptor b [KO:K02583]
118381620  nradd; tumor necrosis factor receptor superfamily member 16 [KO:K02583]
118364403  high affinity nerve growth factor receptor-like [KO:K03176] [EC:2.7.10.1]
118367456  high affinity nerve growth factor receptor [KO:K03176] [EC:2.7.10.1]
118391497  BDNF/NT-3 growth factors receptor-like [KO:K04360] [EC:2.7.10.1]
118388023  BDNF/NT-3 growth factors receptor-like [KO:K04360] [EC:2.7.10.1]
118392951  ntrk2a; neurotrophic tyrosine kinase, receptor, type 2a [KO:K04360] [EC:2.7.10.1]
118358081  BDNF/NT-3 growth factors receptor-like isoform X1 [KO:K04360] [EC:2.7.10.1]
118394862  insulin receptor-like [KO:K04527] [EC:2.7.10.1]
118377063  insulin receptor-like [KO:K04527] [EC:2.7.10.1]
118358912  insulin receptor-like [KO:K04527] [EC:2.7.10.1]
118402477  insulin receptor-like [KO:K04527] [EC:2.7.10.1]
118401242  insulin-like growth factor 1 receptor [KO:K05087] [EC:2.7.10.1]
118396693  igf1ra; insulin-like growth factor 1a receptor [KO:K05087] [EC:2.7.10.1]
118358652  pdgfra; platelet-derived growth factor receptor alpha [KO:K04363] [EC:2.7.10.1]
118380692  platelet-derived growth factor receptor alpha-like [KO:K04363] [EC:2.7.10.1]
118383741  platelet-derived growth factor receptor beta-like isoform X1 [KO:K05089] [EC:2.7.10.1]
118376080  pdgfrb; platelet-derived growth factor receptor beta isoform X1 [KO:K05089] [EC:2.7.10.1]
118390546  platelet-derived growth factor receptor beta-like isoform X1 [KO:K05089] [EC:2.7.10.1]
118363376  macrophage colony-stimulating factor 1 receptor 1-like isoform X1 [KO:K05090] [EC:2.7.10.1]
118385739  macrophage colony-stimulating factor 1 receptor 1 [KO:K05090] [EC:2.7.10.1]
118376065  macrophage colony-stimulating factor 1 receptor 1-like isoform X1 [KO:K05090] [EC:2.7.10.1]
118390547  macrophage colony-stimulating factor 1 receptor 1-like isoform X1 [KO:K05090] [EC:2.7.10.1]
118358651  kita; mast/stem cell growth factor receptor kita isoform X1 [KO:K05091] [EC:2.7.10.1]
118392541  mast/stem cell growth factor receptor Kit-like isoform X1 [KO:K05091] [EC:2.7.10.1]
127923922  mast/stem cell growth factor receptor kita-like [KO:K05091] [EC:2.7.10.1]
118372534  flt3; receptor-type tyrosine-protein kinase FLT3 isoform X1 [KO:K05092] [EC:2.7.10.1]
118378053  receptor-type tyrosine-protein kinase FLT3-like isoform X1 [KO:K05092] [EC:2.7.10.1]
118377338  vascular endothelial growth factor receptor kdr-like [KO:K05096] [EC:2.7.10.1]
118363440  vascular endothelial growth factor receptor kdr-like [KO:K05096] [EC:2.7.10.1]
118378058  vascular endothelial growth factor receptor 1-like isoform X1 [KO:K05096] [EC:2.7.10.1]
127913784  LOW QUALITY PROTEIN: vascular endothelial growth factor receptor 3-like [KO:K05097] [EC:2.7.10.1]
127929754  vascular endothelial growth factor receptor 3-like [KO:K05097] [EC:2.7.10.1]
118359034  kdr; vascular endothelial growth factor receptor 2 isoform X1 [KO:K05098] [EC:2.7.10.1]
118370727  met; hepatocyte growth factor receptor [KO:K05099] [EC:2.7.10.1]
118400969  hepatocyte growth factor receptor-like [KO:K05099] [EC:2.7.10.1]
118381796  tek; tyrosine-protein kinase receptor Tie-2 isoform X1 [KO:K05121] [EC:2.7.10.1]
118360952  ephrin type-A receptor 2-like [KO:K05103] [EC:2.7.10.1]
118388281  ephrin type-A receptor 2-like isoform X1 [KO:K05103] [EC:2.7.10.1]
118399999  ephrin type-A receptor 2-like isoform X1 [KO:K05103] [EC:2.7.10.1]
118359779  epha2b; ephrin type-A receptor 2 [KO:K05103] [EC:2.7.10.1]
118369505  proto-oncogene tyrosine-protein kinase receptor Ret [KO:K05126] [EC:2.7.10.1]
118402076  proto-oncogene tyrosine-protein kinase receptor Ret-like [KO:K05126] [EC:2.7.10.1]
118365702  growth factor receptor-bound protein 2-like [KO:K04364]
118389304  growth factor receptor-bound protein 2-like [KO:K04364]
118365576  growth factor receptor-bound protein 2 [KO:K04364]
118384680  growth factor receptor-bound protein 2 [KO:K04364]
118378050  sos2; son of sevenless homolog 2 [KO:K03099]
118389101  son of sevenless homolog 1-like isoform X1 [KO:K03099]
118365065  son of sevenless homolog 1-like isoform X5 [KO:K03099]
127915780  son of sevenless homolog 2-like [KO:K03099]
118370933  GTPase HRas [KO:K02833]
118395741  GTPase HRas [KO:K02833]
118401106  GTPase KRas isoform X1 [KO:K07827]
118395795  kras; GTPase KRas isoform X1 [KO:K07827]
118380185  zgc:55558; GTPase KRas [KO:K07827]
118358954  ras-related protein R-Ras-like isoform X1 [KO:K07830]
118362605  ras-related protein R-Ras2 [KO:K07830]
118371439  rras2; ras-related protein R-Ras2 [KO:K07830]
118384254  rras; ras-related protein R-Ras [KO:K07830]
118370204  ras-related protein M-Ras isoform X1 [KO:K07831]
118386376  mrasa; ras-related protein M-Ras [KO:K07831]
118366973  ras-related protein M-Ras-like [KO:K07831]
118393428  araf; serine/threonine-protein kinase A-Raf [KO:K08845] [EC:2.7.11.1]
118358512  serine/threonine-protein kinase A-Raf-like isoform X1 [KO:K08845] [EC:2.7.11.1]
127926940  LOW QUALITY PROTEIN: serine/threonine-protein kinase B-raf-like [KO:K04365] [EC:2.7.11.1]
127923762  serine/threonine-protein kinase B-raf-like [KO:K04365] [EC:2.7.11.1]
118361399  raf1a; raf-1 proto-oncogene, serine/threonine kinase a isoform X1 [KO:K04366] [EC:2.7.11.1]
118359627  RAF proto-oncogene serine/threonine-protein kinase [KO:K04366] [EC:2.7.11.1]
118359232  dual specificity mitogen-activated protein kinase kinase 2-like [KO:K04369] [EC:2.7.12.2]
118401816  map2k2b; dual specificity mitogen-activated protein kinase kinase 2b [KO:K04369] [EC:2.7.12.2]
118389751  dual specificity mitogen-activated protein kinase kinase 2 [KO:K04369] [EC:2.7.12.2]
118380828  mitogen-activated protein kinase 1-like isoform X1 [KO:K04371] [EC:2.7.11.24]
127907089  mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
118358931  mitogen-activated protein kinase 1-like [KO:K04371] [EC:2.7.11.24]
118384271  mitogen-activated protein kinase 1-like [KO:K04371] [EC:2.7.11.24]
118359178  MAP kinase-interacting serine/threonine-protein kinase 2-like [KO:K04372] [EC:2.7.11.1]
118401648  MAP kinase-interacting serine/threonine-protein kinase 2-like isoform X1 [KO:K04372] [EC:2.7.11.1]
118401533  mknk1; MAP kinase-interacting serine/threonine-protein kinase 1 isoform X1 [KO:K04372] [EC:2.7.11.1]
118390487  MAP kinase-interacting serine/threonine-protein kinase 2-like isoform X1 [KO:K04372] [EC:2.7.11.1]
127919292  MAP kinase-interacting serine/threonine-protein kinase 2-like [KO:K04372] [EC:2.7.11.1]
118368535  ribosomal protein S6 kinase alpha-1 isoform X1 [KO:K04373] [EC:2.7.11.1]
118385041  ribosomal protein S6 kinase alpha-3 isoform X1 [KO:K04373] [EC:2.7.11.1]
118361182  ribosomal protein S6 kinase alpha-3 isoform X1 [KO:K04373] [EC:2.7.11.1]
118362266  ribosomal protein S6 kinase 2 alpha-like isoform X1 [KO:K04373] [EC:2.7.11.1]
118375534  rps6kal; ribosomal protein S6 kinase alpha-6 [KO:K04373] [EC:2.7.11.1]
118398234  ribosomal protein S6 kinase alpha-2 isoform X1 [KO:K04373] [EC:2.7.11.1]
118390450  ribosomal protein S6 kinase alpha-3-like [KO:K04373] [EC:2.7.11.1]
118380004  ribosomal protein S6 kinase alpha-3-like isoform X1 [KO:K04373] [EC:2.7.11.1]
118357689  ribosomal protein S6 kinase alpha-2 [KO:K04373] [EC:2.7.11.1]
118374235  atf4a; cyclic AMP-dependent transcription factor ATF-4 [KO:K04374]
118365155  cyclic AMP-dependent transcription factor ATF-4-like [KO:K04374]
118384372  cyclic AMP-dependent transcription factor ATF-4-like isoform X1 [KO:K04374]
118359562  elk1; ETS domain-containing protein Elk-1 isoform X1 [KO:K04375]
118388509  ETS domain-containing protein Elk-4 isoform X1 [KO:K04376]
118400255  ETS domain-containing protein Elk-4-like isoform X2 [KO:K04376]
118370058  transcriptional regulator Myc-2-like [KO:K04377]
118388909  mych; myelocytomatosis oncogene homolog [KO:K04377]
118402411  transcriptional regulator Myc-B [KO:K04377]
118361486  transcriptional regulator Myc-like [KO:K04377]
118373368  transcriptional regulator Myc [KO:K04377]
118402412  serum response factor-like isoform X1 [KO:K04378]
118389094  serum response factor isoform X1 [KO:K04378]
118365059  serum response factor-like isoform X1 [KO:K04378]
127919863  serum response factor-like [KO:K04378]
118369242  fosaa; protein c-Fos isoform X2 [KO:K04379]
118362495  protein c-Fos-like isoform X1 [KO:K04379]
118376443  fosab; v-fos FBJ murine osteosarcoma viral oncogene homolog Ab [KO:K04379]
118376444  protein c-Fos-like [KO:K04379]
118382833  protein c-Fos-like [KO:K04379]
118382832  protein c-Fos-like [KO:K04379]
118365168  microtubule-associated protein tau-like isoform X1 [KO:K04380]
118365200  mapta; microtubule-associated protein tau isoform X1 [KO:K04380]
118384392  microtubule-associated protein tau isoform X1 [KO:K04380]
118371160  stathmin-like [KO:K04381]
118364165  stathmin-like [KO:K04381]
118399480  stathmin-like [KO:K04381]
118367241  stmn1b; stathmin 1b [KO:K04381]
118368882  cytosolic phospholipase A2 gamma-like [KO:K16342] [EC:3.1.1.4]
118368884  cytosolic phospholipase A2 zeta-like [KO:K16342] [EC:3.1.1.4]
118369656  cytosolic phospholipase A2 zeta-like [KO:K16342] [EC:3.1.1.4]
118394538  cytosolic phospholipase A2-like isoform X1 [KO:K16342] [EC:3.1.1.4]
118386613  pla2g4ab; cytosolic phospholipase A2 [KO:K16342] [EC:3.1.1.4]
118358888  cytosolic phospholipase A2-like [KO:K16342] [EC:3.1.1.4]
118400532  cytosolic phospholipase A2 zeta-like isoform X1 [KO:K16342] [EC:3.1.1.4]
118367411  tumor necrosis factor [KO:K03156]
118378789  tumor necrosis factor-like [KO:K03156]
118380315  tumor necrosis factor [KO:K03156]
118393554  interleukin-1 beta [KO:K04519]
118373089  interleukin-1 beta-like [KO:K04519]
118375506  il1b; interleukin-1 beta [KO:K04519]
127911767  interleukin-1 beta-like isoform X1 [KO:K04519]
127911768  interleukin-1 beta-like [KO:K04519]
127911769  interleukin-1 beta-like [KO:K04519]
118385063  transforming growth factor beta-1 proprotein isoform X1 [KO:K13375]
118390427  transforming growth factor beta-1 proprotein-like [KO:K13375]
118381881  tgfb1a; transforming growth factor, beta 1a [KO:K13375]
118364018  transforming growth factor beta-2 proprotein-like [KO:K13376]
118367254  transforming growth factor beta-2 proprotein-like [KO:K13376]
118381108  tgfb5; transforming growth factor beta-2 proprotein isoform X1 [KO:K13376]
118362491  tgfb3; transforming growth factor beta-3 proprotein [KO:K13377]
118397920  transforming growth factor beta-3 proprotein-like isoform X1 [KO:K13377]
118368308  transforming growth factor beta-3 proprotein-like [KO:K13377]
118373947  tumor necrosis factor receptor superfamily member 1A isoform X1 [KO:K03158]
118367899  tumor necrosis factor receptor superfamily member 1A-like [KO:K03158]
118366861  interleukin-1 receptor type 1-like [KO:K04386]
118366014  interleukin-1 receptor accessory protein [KO:K04723]
118402047  TGF-beta receptor type-1-like isoform X1 [KO:K04674] [EC:2.7.11.30]
118371655  TGF-beta receptor type-1-like isoform X1 [KO:K04674] [EC:2.7.11.30]
118394719  TGF-beta receptor type-1 isoform X1 [KO:K04674] [EC:2.7.11.30]
118371754  TGF-beta receptor type-1 isoform X1 [KO:K04674] [EC:2.7.11.30]
118386321  TGF-beta receptor type-2-like isoform X1 [KO:K04388] [EC:2.7.11.30]
118398317  TGF-beta receptor type-2-like [KO:K04388] [EC:2.7.11.30]
118399140  TGF-beta receptor type-2-like isoform X1 [KO:K04388] [EC:2.7.11.30]
118366880  TGF-beta receptor type-2 isoform X1 [KO:K04388] [EC:2.7.11.30]
118372136  CD40 ligand-like [KO:K04389]
118376928  CD40 ligand-like isoform X1 [KO:K04389]
118358720  tumor necrosis factor ligand superfamily member 6-like [KO:K04389]
118391875  tumor necrosis factor ligand superfamily member 6-like [KO:K04389]
118369720  tumor necrosis factor receptor superfamily member 6-like isoform X1 [KO:K04390]
118400188  tumor necrosis factor receptor superfamily member 6-like isoform X1 [KO:K04390]
118402918  ras-related C3 botulinum toxin substrate 1 [KO:K04392]
118372953  ras-related C3 botulinum toxin substrate 1 [KO:K04392]
118375816  ras-related C3 botulinum toxin substrate 1-like isoform X1 [KO:K04392]
118375264  ras-related C3 botulinum toxin substrate 2 [KO:K07860]
118365648  ras-related C3 botulinum toxin substrate 2 isoform X1 [KO:K07860]
118380868  ras-related C3 botulinum toxin substrate 2-like isoform X1 [KO:K07860]
118402919  rac3b; ras-related C3 botulinum toxin substrate 3b isoform X1 [KO:K07861]
118370992  ras-related C3 botulinum toxin substrate 3-like isoform X2 [KO:K07861]
127930267  ras-related C3 botulinum toxin substrate 3-like [KO:K07861]
118359862  cell division control protein 42 homolog isoform X1 [KO:K04393]
118360867  cell division control protein 42 homolog isoform X1 [KO:K04393]
118367889  cell division control protein 42 homolog [KO:K04393]
118388502  cell division control protein 42 homolog isoform X2 [KO:K04393]
118374223  cell division control protein 42 homolog [KO:K04393]
118398211  cell division control protein 42 homolog [KO:K04393]
118399284  cell division control protein 42 homolog [KO:K04393]
118400245  cell division control protein 42 homolog isoform X2 [KO:K04393]
118393895  tumor necrosis factor receptor type 1-associated DEATH domain protein [KO:K03171]
118359756  tumor necrosis factor receptor type 1-associated DEATH domain protein-like [KO:K03171]
118393409  caspase-3-like [KO:K02187] [EC:3.4.22.56]
118395316  casp3a; caspase-3a [KO:K02187] [EC:3.4.22.56]
118362899  caspase-3-like [KO:K02187] [EC:3.4.22.56]
118363298  casp3b; caspase-3b isoform X1 [KO:K02187] [EC:3.4.22.56]
118385316  TNF receptor-associated factor 2-like isoform X1 [KO:K03173] [EC:2.3.2.27]
118385484  TNF receptor-associated factor 2-like [KO:K03173] [EC:2.3.2.27]
118393434  TNF receptor-associated factor 2-like isoform X1 [KO:K03173] [EC:2.3.2.27]
118387519  traf2b; TNF receptor-associated factor 2 isoform X1 [KO:K03173] [EC:2.3.2.27]
118379005  TNF receptor-associated factor 2-like isoform X1 [KO:K03173] [EC:2.3.2.27]
118398192  death domain-associated protein 6-like isoform X1 [KO:K02308]
118399298  daxx; death domain-associated protein 6 isoform X2 [KO:K02308]
127916490  myd88; myeloid differentiation primary response protein MyD88 [KO:K04729]
118377759  irak1; interleukin-1 receptor-associated kinase 1 [KO:K04730] [EC:2.7.11.1]
118396543  interleukin-1 receptor-associated kinase 4-like [KO:K04733] [EC:2.7.11.1]
118381203  traf6; TNF receptor-associated factor 6 [KO:K03175] [EC:2.3.2.27]
118385340  growth arrest and DNA damage-inducible protein GADD45 gamma-like [KO:K04402]
118385341  growth arrest and DNA damage-inducible protein GADD45 gamma-like [KO:K04402]
118393171  growth arrest and DNA damage-inducible protein GADD45 alpha-like [KO:K04402]
118393486  gadd45ga; growth arrest and DNA-damage-inducible, gamma a [KO:K04402]
118402391  gadd45aa; growth arrest and DNA-damage-inducible, alpha, a isoform X1 [KO:K04402]
118394493  growth arrest and DNA damage-inducible protein GADD45 alpha-like isoform X1 [KO:K04402]
118387498  growth arrest and DNA damage-inducible protein GADD45 gamma-like [KO:K04402]
118387893  growth arrest and DNA damage-inducible protein GADD45 beta-like [KO:K04402]
118387999  growth arrest and DNA damage-inducible protein GADD45 gamma-like [KO:K04402]
118397597  growth arrest and DNA damage-inducible protein GADD45 beta-like [KO:K04402]
118358540  growth arrest and DNA damage-inducible protein GADD45 gamma-like [KO:K04402]
118358984  growth arrest and DNA damage-inducible protein GADD45 alpha [KO:K04402]
118381064  tab1; LOW QUALITY PROTEIN: TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 [KO:K04403]
118386818  tab2; TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 isoform X1 [KO:K04404]
118398736  TGF-beta-activated kinase 1 and MAP3K7-binding protein 2-like isoform X4 [KO:K04404]
118368653  evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial isoform X1 [KO:K04405]
118389102  mitogen-activated protein kinase kinase kinase kinase 3-like isoform X1 [KO:K04406] [EC:2.7.11.1]
118378972  mitogen-activated protein kinase kinase kinase kinase 3-like [KO:K04406] [EC:2.7.11.1]
118399112  mitogen-activated protein kinase kinase kinase kinase 3-like isoform X3 [KO:K04406] [EC:2.7.11.1]
118386305  mitogen-activated protein kinase kinase kinase kinase 4-like isoform X1 [KO:K04407] [EC:2.7.11.1]
118363328  mitogen-activated protein kinase kinase kinase kinase 4 isoform X1 [KO:K04407] [EC:2.7.11.1]
118363185  mitogen-activated protein kinase kinase kinase kinase 4-like [KO:K04407] [EC:2.7.11.1]
118376579  mitogen-activated protein kinase kinase kinase kinase 4-like isoform X1 [KO:K04407] [EC:2.7.11.1]
118366857  mitogen-activated protein kinase kinase kinase kinase 4-like isoform X1 [KO:K04407] [EC:2.7.11.1]
118375194  mitogen-activated protein kinase kinase kinase kinase 4-like isoform X1 [KO:K04407] [EC:2.7.11.1]
118396013  pak1; serine/threonine-protein kinase PAK 1 isoform X1 [KO:K04409] [EC:2.7.11.1]
118396850  serine/threonine-protein kinase PAK 1-like [KO:K04409] [EC:2.7.11.1]
118363198  serine/threonine-protein kinase PAK 2-like [KO:K04410] [EC:2.7.11.1]
118363874  serine/threonine-protein kinase PAK 2-like isoform X1 [KO:K04410] [EC:2.7.11.1]
118390612  pak2b; serine/threonine-protein kinase PAK 2b isoform X1 [KO:K04410] [EC:2.7.11.1]
118359160  serine/threonine-protein kinase PAK 2 isoform X2 [KO:K04410] [EC:2.7.11.1]
118370032  serine/threonine-protein kinase 4-like isoform X1 [KO:K04411]
118375478  serine/threonine-protein kinase 3 [KO:K04412]
118374322  serine/threonine-protein kinase 3 [KO:K04412]
118391892  mitogen-activated protein kinase kinase kinase kinase 2 isoform X1 [KO:K04414] [EC:2.7.11.1]
118369146  mitogen-activated protein kinase kinase kinase kinase 2-like isoform X1 [KO:K04414] [EC:2.7.11.1]
118390541  mitogen-activated protein kinase kinase kinase kinase 2-like [KO:K04414] [EC:2.7.11.1]
118384955  mitogen-activated protein kinase kinase kinase kinase 2-like [KO:K04414] [EC:2.7.11.1]
118361568  mitogen-activated protein kinase kinase kinase 8-like [KO:K04415] [EC:2.7.11.25]
118374792  LOW QUALITY PROTEIN: mitogen-activated protein kinase kinase kinase 8-like [KO:K04415] [EC:2.7.11.25]
118385561  mitogen-activated protein kinase kinase kinase 1-like isoform X1 [KO:K04416] [EC:2.7.11.25]
118387265  mitogen-activated protein kinase kinase kinase 1 isoform X1 [KO:K04416] [EC:2.7.11.25]
118368669  mitogen-activated protein kinase kinase kinase 11-like [KO:K04419] [EC:2.7.11.25]
118391901  mitogen-activated protein kinase kinase kinase 11 [KO:K04419] [EC:2.7.11.25]
118363754  mitogen-activated protein kinase kinase kinase 2-like [KO:K04420] [EC:2.7.11.25]
118370219  mitogen-activated protein kinase kinase kinase 2-like [KO:K04420] [EC:2.7.11.25]
118374908  map3k3; mitogen-activated protein kinase kinase kinase 3 isoform X1 [KO:K04421] [EC:2.7.11.25]
118377367  mitogen-activated protein kinase kinase kinase 3-like [KO:K04421] [EC:2.7.11.25]
118382476  mitogen-activated protein kinase kinase kinase 3-like [KO:K04421] [EC:2.7.11.25]
118362010  map3k9; mitogen-activated protein kinase kinase kinase 9 [KO:K04417] [EC:2.7.11.25]
118397116  mitogen-activated protein kinase kinase kinase 10-like [KO:K04418] [EC:2.7.11.25]
118357376  map3k10; mitogen-activated protein kinase kinase kinase 10 [KO:K04418] [EC:2.7.11.25]
118402838  map3k21; mitogen-activated protein kinase kinase kinase 21 isoform X1 [KO:K17534] [EC:2.7.11.25]
118371014  mitogen-activated protein kinase kinase kinase 21-like isoform X1 [KO:K17534] [EC:2.7.11.25]
118361354  map3k12; mitogen-activated protein kinase kinase kinase 12 [KO:K04423] [EC:2.7.11.25]
118380936  mitogen-activated protein kinase kinase kinase 12-like isoform X1 [KO:K04423] [EC:2.7.11.25]
118359678  mitogen-activated protein kinase kinase kinase 12-like isoform X1 [KO:K04423] [EC:2.7.11.25]
118375196  si:ch211-45c16.2; mitogen-activated protein kinase kinase kinase 13 [KO:K04422] [EC:2.7.11.25]
118386047  mitogen-activated protein kinase kinase kinase 20-like isoform X2 [KO:K04424] [EC:2.7.11.25]
118395070  mitogen-activated protein kinase kinase kinase 20-like [KO:K04424] [EC:2.7.11.25]
118367065  mitogen-activated protein kinase kinase kinase 20-like isoform X1 [KO:K04424] [EC:2.7.11.25]
118402499  mitogen-activated protein kinase kinase kinase 20-like [KO:K04424] [EC:2.7.11.25]
118386825  mitogen-activated protein kinase kinase kinase 5-like isoform X1 [KO:K04426] [EC:2.7.11.25]
118364282  mitogen-activated protein kinase kinase kinase 5-like [KO:K04426] [EC:2.7.11.25]
118367356  mitogen-activated protein kinase kinase kinase 5-like [KO:K04426] [EC:2.7.11.25]
118398724  mitogen-activated protein kinase kinase kinase 5-like [KO:K04426] [EC:2.7.11.25]
118386791  mitogen-activated protein kinase kinase kinase 7-like isoform X7 [KO:K04427] [EC:2.7.11.25]
118362329  mitogen-activated protein kinase kinase kinase 7-like [KO:K04427] [EC:2.7.11.25]
118368467  mitogen-activated protein kinase kinase kinase 7-like [KO:K04427] [EC:2.7.11.25]
118396657  mitogen-activated protein kinase kinase kinase 4-like isoform X1 [KO:K04428] [EC:2.7.11.25]
118402794  LOW QUALITY PROTEIN: mitogen-activated protein kinase kinase kinase 4-like [KO:K04428] [EC:2.7.11.25]
118358640  serine/threonine-protein kinase TAO2-like isoform X1 [KO:K04429] [EC:2.7.11.1]
118362429  serine/threonine-protein kinase TAO1 [KO:K04429] [EC:2.7.11.1]
118387679  serine/threonine-protein kinase TAO3-like [KO:K04429] [EC:2.7.11.1]
118384312  serine/threonine-protein kinase TAO2-like isoform X1 [KO:K04429] [EC:2.7.11.1]
118393537  taok3a; serine/threonine-protein kinase TAO3 [KO:K04429] [EC:2.7.11.1]
118363806  taok2b; serine/threonine-protein kinase TAO2 isoform X1 [KO:K04429] [EC:2.7.11.1]
118371706  serine/threonine-protein kinase TAO1 [KO:K04429] [EC:2.7.11.1]
118391409  serine/threonine-protein kinase TAO3-like [KO:K04429] [EC:2.7.11.1]
118384906  LOW QUALITY PROTEIN: serine/threonine-protein kinase TAO1-like [KO:K04429] [EC:2.7.11.1]
118371984  serine/threonine-protein kinase TAO3-like isoform X1 [KO:K04429] [EC:2.7.11.1]
118368781  dual specificity mitogen-activated protein kinase kinase 4-like isoform X1 [KO:K04430] [EC:2.7.12.2]
118365629  dual specificity mitogen-activated protein kinase kinase 4 isoform X1 [KO:K04430] [EC:2.7.12.2]
118357393  map2k4b; dual specificity mitogen-activated protein kinase kinase 4b isoform X1 [KO:K04430] [EC:2.7.12.2]
118384713  dual specificity mitogen-activated protein kinase kinase 4-like isoform X1 [KO:K04430] [EC:2.7.12.2]
118364866  dual specificity mitogen-activated protein kinase kinase 7-like isoform X1 [KO:K04431] [EC:2.7.12.2]
118374394  dual specificity mitogen-activated protein kinase kinase 7-like isoform X1 [KO:K04431] [EC:2.7.12.2]
118375502  dual specificity mitogen-activated protein kinase kinase 6 [KO:K04433] [EC:2.7.12.2]
118397477  dual specificity mitogen-activated protein kinase kinase 6 isoform X1 [KO:K04433] [EC:2.7.12.2]
118394119  C-Jun-amino-terminal kinase-interacting protein 1-like isoform X1 [KO:K04434]
118400813  C-Jun-amino-terminal kinase-interacting protein 1-like [KO:K04434]
118401151  C-Jun-amino-terminal kinase-interacting protein 2-like isoform X1 [KO:K04435]
118395711  mapk8ip2; C-Jun-amino-terminal kinase-interacting protein 2 isoform X1 [KO:K04435]
118384115  mapk8ip3; C-Jun-amino-terminal kinase-interacting protein 3 isoform X1 [KO:K04436]
118358962  C-Jun-amino-terminal kinase-interacting protein 3-like isoform X1 [KO:K04436]
118376088  flna; filamin-A isoform X1 [KO:K04437]
118385353  crk-like protein [KO:K04438]
118387488  crk-like protein [KO:K04438]
118397229  adapter molecule crk-like [KO:K04438]
118389911  adapter molecule crk-like [KO:K04438]
118390947  adapter molecule crk-like [KO:K04438]
118384947  adapter molecule crk-like [KO:K04438]
118383979  arrestin red cell-like [KO:K04439]
118390144  arrestin red cell [KO:K04439]
118376321  arrestin red cell-like isoform X1 [KO:K04439]
118391215  arrestin red cell isoform X1 [KO:K04439]
118381477  arrb1; beta-arrestin-1 isoform X1 [KO:K04439]
118369466  mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
118402372  mitogen-activated protein kinase 8-like isoform X1 [KO:K04440] [EC:2.7.11.24]
118373295  mitogen-activated protein kinase 10-like isoform X1 [KO:K04440] [EC:2.7.11.24]
118387819  mitogen-activated protein kinase 10 isoform X1 [KO:K04440] [EC:2.7.11.24]
118385734  mapk9; mitogen-activated protein kinase 9 [KO:K04440] [EC:2.7.11.24]
118375883  mitogen-activated protein kinase 9-like isoform X1 [KO:K04440] [EC:2.7.11.24]
118367713  mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
118357754  mitogen-activated protein kinase 8-like isoform X1 [KO:K04440] [EC:2.7.11.24]
118360165  mitogen-activated protein kinase 14A isoform X1 [KO:K04441] [EC:2.7.11.24]
118360174  mitogen-activated protein kinase 14A-like isoform X1 [KO:K04441] [EC:2.7.11.24]
118401077  mapk12a; mitogen-activated protein kinase 12 isoform X1 [KO:K04441] [EC:2.7.11.24]
118360604  mitogen-activated protein kinase 14A-like [KO:K04441] [EC:2.7.11.24]
118361231  mapk13; mitogen-activated protein kinase 13 [KO:K04441] [EC:2.7.11.24]
118373032  mitogen-activated protein kinase 14A-like isoform X1 [KO:K04441] [EC:2.7.11.24]
118395817  mitogen-activated protein kinase 12-like [KO:K04441] [EC:2.7.11.24]
118365973  mitogen-activated protein kinase 11-like [KO:K04441] [EC:2.7.11.24]
118389610  mitogen-activated protein kinase 14A-like [KO:K04441] [EC:2.7.11.24]
118366309  mitogen-activated protein kinase 12-like isoform X1 [KO:K04441] [EC:2.7.11.24]
118399916  mitogen-activated protein kinase 14A-like isoform X1 [KO:K04441] [EC:2.7.11.24]
118392440  mitogen-activated protein kinase 12-like isoform X1 [KO:K04441] [EC:2.7.11.24]
118392441  mitogen-activated protein kinase 11 [KO:K04441] [EC:2.7.11.24]
118370857  MAP kinase-activated protein kinase 5-like isoform X1 [KO:K04442] [EC:2.7.11.1]
118357987  MAP kinase-activated protein kinase 5 isoform X1 [KO:K04442] [EC:2.7.11.1]
118361436  MAP kinase-activated protein kinase 2-like [KO:K04443] [EC:2.7.11.1]
118380621  MAP kinase-activated protein kinase 2-like isoform X1 [KO:K04443] [EC:2.7.11.1]
118359606  MAP kinase-activated protein kinase 2-like [KO:K04443] [EC:2.7.11.1]
118388406  MAP kinase-activated protein kinase 2 [KO:K04444] [EC:2.7.11.1]
118388595  MAP kinase-activated protein kinase 2-like [KO:K04444] [EC:2.7.11.1]
118400142  MAP kinase-activated protein kinase 2-like [KO:K04444] [EC:2.7.11.1]
118399776  MAP kinase-activated protein kinase 2-like isoform X1 [KO:K04444] [EC:2.7.11.1]
118362867  rps6ka5; ribosomal protein S6 kinase alpha-5 isoform X1 [KO:K04445] [EC:2.7.11.1]
118378685  ribosomal protein S6 kinase alpha-5-like isoform X1 [KO:K04445] [EC:2.7.11.1]
118385091  ribosomal protein S6 kinase alpha-4-like [KO:K16510] [EC:2.7.11.1]
118390384  LOW QUALITY PROTEIN: ribosomal protein S6 kinase alpha-4-like [KO:K16510] [EC:2.7.11.1]
118378734  cdc25b; LOW QUALITY PROTEIN: M-phase inducer phosphatase 2 [KO:K05866] [EC:3.1.3.48]
118380261  M-phase inducer phosphatase 2-like isoform X1 [KO:K05866] [EC:3.1.3.48]
118364026  nuclear factor of activated T-cells, cytoplasmic 1-like isoform X1 [KO:K04446]
118367295  nuclear factor of activated T-cells, cytoplasmic 1-like isoform X1 [KO:K04446]
118375190  nuclear factor of activated T-cells, cytoplasmic 1-like isoform X2 [KO:K04446]
118399170  nfatc1; nuclear factor of activated T-cells, cytoplasmic 1 [KO:K04446]
118372868  nuclear factor of activated T-cells, cytoplasmic 3-like isoform X1 [KO:K17333]
127913234  nuclear factor of activated T-cells, cytoplasmic 3-like isoform X1 [KO:K17333]
118395918  nuclear factor of activated T-cells, cytoplasmic 3-like [KO:K17333]
118400993  nuclear factor of activated T-cells, cytoplasmic 3-like [KO:K17333]
118387243  transcription factor Jun-like [KO:K04448]
118391743  june; junE proto-oncogene, AP-1 transcription factor subunit [KO:K04448]
118394851  transcription factor Jun-like [KO:K04448]
118375408  transcription factor Jun-like [KO:K04448]
118359083  jun; transcription factor AP-1 isoform X1 [KO:K04448]
118391906  transcription factor Jun-like [KO:K04448]
118401470  transcription factor JunD-like [KO:K04449]
118402280  transcription factor JunD-like [KO:K04449]
118394505  transcription factor JunD-like [KO:K04449]
118388206  transcription factor JunD-like [KO:K04449]
118367052  atf2; cyclic AMP-dependent transcription factor ATF-2 isoform X1 [KO:K04450]
118368687  LOW QUALITY PROTEIN: cellular tumor antigen p53-like [KO:K04451]
118390576  tp53; cellular tumor antigen p53 [KO:K04451]
118391918  cellular tumor antigen p53-like isoform X1 [KO:K04451]
118378334  DNA damage-inducible transcript 3 protein-like [KO:K04452]
118379213  ddit3; DNA damage-inducible transcript 3 protein isoform X1 [KO:K04452]
118362464  protein max-like isoform X1 [KO:K04453]
118377164  max; protein max isoform X1 [KO:K04453]
118374180  protein max-like [KO:K04453]
118368336  protein max-like isoform X1 [KO:K04453]
118394027  myocyte-specific enhancer factor 2C-like isoform X1 [KO:K04454]
118371062  mef2ca; myocyte enhancer factor 2ca isoform X1 [KO:K04454]
118388068  myocyte-specific enhancer factor 2C-like isoform X1 [KO:K04454]
118358034  myocyte-specific enhancer factor 2C-like isoform X1 [KO:K04454]
118387685  heat shock protein beta-1-like [KO:K04455]
118376682  LOW QUALITY PROTEIN: heat shock protein beta-1-like [KO:K04455]
118391010  heat shock protein beta-1 [KO:K04455]
118391712  heat shock protein beta-1-like [KO:K04455]
118362163  akt1; RAC-alpha serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
118386979  RAC-alpha serine/threonine-protein kinase-like isoform X1 [KO:K04456] [EC:2.7.11.1]
118385730  RAC-beta serine/threonine-protein kinase-like [KO:K04456] [EC:2.7.11.1]
118364993  RAC-gamma serine/threonine-protein kinase-like [KO:K04456] [EC:2.7.11.1]
118389183  RAC-gamma serine/threonine-protein kinase-like [KO:K04456] [EC:2.7.11.1]
118397568  akt2; RAC-beta serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
118398585  RAC-alpha serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
118390569  RAC-beta serine/threonine-protein kinase-like [KO:K04456] [EC:2.7.11.1]
118391055  RAC-beta serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
118368360  RAC-alpha serine/threonine-protein kinase-like isoform X1 [KO:K04456] [EC:2.7.11.1]
118402823  akt3a; RAC-gamma serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
118362571  protein phosphatase 1A isoform X1 [KO:K04457] [EC:3.1.3.16]
118397132  ppm1na; protein phosphatase, Mg2+/Mn2+ dependent, 1Na (putative) [KO:K04457] [EC:3.1.3.16]
118395346  protein phosphatase 1A-like [KO:K04457] [EC:3.1.3.16]
118390232  ppm1nb; protein phosphatase, Mg2+/Mn2+ dependent, 1Nb (putative) [KO:K04457] [EC:3.1.3.16]
118398553  ppm1ab; protein phosphatase, Mg2+/Mn2+ dependent, 1Ab [KO:K04457] [EC:3.1.3.16]
118391294  protein phosphatase 1A-like [KO:K04457] [EC:3.1.3.16]
118368238  protein phosphatase 1A-like isoform X1 [KO:K04457] [EC:3.1.3.16]
118383133  ptprr; receptor-type tyrosine-protein phosphatase R isoform X1 [KO:K04458] [EC:3.1.3.48]
118358784  tyrosine-protein phosphatase non-receptor type 5-like [KO:K18018] [EC:3.1.3.48]
118396109  tyrosine-protein phosphatase non-receptor type 5 [KO:K18018] [EC:3.1.3.48]
118375450  tyrosine-protein phosphatase non-receptor type 7-like isoform X1 [KO:K18019] [EC:3.1.3.48]
118361027  tyrosine-protein phosphatase non-receptor type 7-like isoform X1 [KO:K18019] [EC:3.1.3.48]
127929767  dusp1; dual specificity protein phosphatase 1 [KO:K21278] [EC:3.1.3.16 3.1.3.48]
118380385  dual specificity protein phosphatase 1 [KO:K21278] [EC:3.1.3.16 3.1.3.48]
118361392  dual specificity protein phosphatase 7-like [KO:K04459] [EC:3.1.3.16 3.1.3.48]
118371100  dual specificity protein phosphatase 4-like [KO:K04459] [EC:3.1.3.16 3.1.3.48]
118371721  dusp2; dual specificity protein phosphatase 2 [KO:K04459] [EC:3.1.3.16 3.1.3.48]
118387758  dual specificity protein phosphatase 4-like [KO:K04459] [EC:3.1.3.16 3.1.3.48]
118396450  dual specificity protein phosphatase 8-like isoform X1 [KO:K04459] [EC:3.1.3.16 3.1.3.48]
118389594  dual specificity protein phosphatase 7-like [KO:K04459] [EC:3.1.3.16 3.1.3.48]
118372914  dusp5; dual specificity protein phosphatase 5 [KO:K04459] [EC:3.1.3.16 3.1.3.48]
118379285  dual specificity protein phosphatase 7-like [KO:K04459] [EC:3.1.3.16 3.1.3.48]
118359333  dual specificity protein phosphatase 8-like isoform X1 [KO:K04459] [EC:3.1.3.16 3.1.3.48]
118359634  dual specificity protein phosphatase 7-like [KO:K04459] [EC:3.1.3.16 3.1.3.48]
118395955  dusp6; dual specificity protein phosphatase 6 [KO:K21946] [EC:3.1.3.16 3.1.3.48]
118400964  dual specificity protein phosphatase 6-like [KO:K21946] [EC:3.1.3.16 3.1.3.48]
118386657  dual specificity protein phosphatase 10-like isoform X1 [KO:K20216] [EC:3.1.3.16 3.1.3.48]
118372430  dual specificity protein phosphatase 10-like [KO:K20216] [EC:3.1.3.16 3.1.3.48]
118357560  dual specificity protein phosphatase 3-like [KO:K17614] [EC:3.1.3.16 3.1.3.48]
118367169  dual specificity protein phosphatase 3-like [KO:K17614] [EC:3.1.3.16 3.1.3.48]
118358975  dual specificity protein phosphatase 3-like [KO:K17614] [EC:3.1.3.16 3.1.3.48]
118397598  serine/threonine-protein phosphatase 5-like [KO:K04460] [EC:3.1.3.16]
118376752  serine/threonine-protein phosphatase 5-like [KO:K04460] [EC:3.1.3.16]
118402817  ppm1ba; protein phosphatase 1B isoform X1 [KO:K04461] [EC:3.1.3.16]
118374115  protein phosphatase 1B-like [KO:K04461] [EC:3.1.3.16]
118357451  protein phosphatase 1B-like isoform X1 [KO:K04461] [EC:3.1.3.16]
118370457  heat shock 70 kDa protein-like [KO:K03283]
118390988  heat shock cognate 70 kDa protein-like [KO:K03283]
127914483  heat shock 70 kDa protein [KO:K03283]
118376275  heat shock 70 kDa protein [KO:K03283]
118365263  LOW QUALITY PROTEIN: heat shock 70 kDa protein [KO:K03283]
118373839  hsc70; heat shock cognate 71 kDa protein [KO:K03283]
118397471  heat shock cognate 70 kDa protein-like [KO:K03283]
118389953  heat shock cognate 70 kDa protein [KO:K03283]
118380972  hspa1b; heat shock 70 kDa protein-like [KO:K03283]
118359484  heat shock cognate 70 kDa protein-like isoform X1 [KO:K03283]
127931225  histone-lysine N-methyltransferase MECOM-like isoform X1 [KO:K04462] [EC:2.1.1.367]
118371328  histone-lysine N-methyltransferase MECOM isoform X1 [KO:K04462] [EC:2.1.1.367]
127920187  map2k5; LOW QUALITY PROTEIN: dual specificity mitogen-activated protein kinase kinase 5 [KO:K04463] [EC:2.7.12.2]
118366739  mapk7; mitogen-activated protein kinase 7 isoform X1 [KO:K04464] [EC:2.7.11.24]
118360783  probable nuclear hormone receptor HR38 [KO:K04465]
118388715  nuclear receptor subfamily 4 group A member 1-like [KO:K04465]
118400421  nuclear receptor subfamily 4 group A member 1-like [KO:K04465]
118359477  probable nuclear hormone receptor HR38 isoform X1 [KO:K04465]
118375729  mitogen-activated protein kinase kinase kinase 14-like isoform X2 [KO:K04466] [EC:2.7.11.25]
118367281  uncharacterized protein LOC118367281 isoform X1 [KO:K04466] [EC:2.7.11.25]
118384507  map3k14a; mitogen-activated protein kinase kinase kinase 14 isoform X1 [KO:K04466] [EC:2.7.11.25]
118363556  inhibitor of nuclear factor kappa-B kinase subunit alpha-like isoform X1 [KO:K04467] [EC:2.7.11.10]
118366609  inhibitor of nuclear factor kappa-B kinase subunit alpha-like isoform X1 [KO:K04467] [EC:2.7.11.10]
118357674  inhibitor of nuclear factor kappa-B kinase subunit alpha-like [KO:K04467] [EC:2.7.11.10]
118371603  ikbkb; LOW QUALITY PROTEIN: inhibitor of nuclear factor kappa-B kinase subunit beta [KO:K07209] [EC:2.7.11.10]
118379875  NF-kappa-B essential modulator-like [KO:K07210]
118376297  LOW QUALITY PROTEIN: NF-kappa-B essential modulator-like [KO:K07210]
118394472  serine/threonine-protein kinase NLK [KO:K04468] [EC:2.7.11.24]
118396878  serine/threonine-protein kinase NLK-like [KO:K04468] [EC:2.7.11.24]
118358915  serine/threonine-protein kinase NLK2-like [KO:K04468] [EC:2.7.11.24]
118384308  serine/threonine-protein kinase NLK2-like [KO:K04468] [EC:2.7.11.24]
118363406  nuclear factor NF-kappa-B p105 subunit-like [KO:K02580]
118376596  nuclear factor NF-kappa-B p105 subunit-like isoform X2 [KO:K02580]
118369397  nuclear factor NF-kappa-B p100 subunit-like isoform X1 [KO:K04469]
118400985  nuclear factor NF-kappa-B p100 subunit-like [KO:K04469]
118368674  transcription factor p65-like isoform X1 [KO:K04735]
118391902  putative transcription factor p65 homolog isoform X1 [KO:K04735]
118397123  transcription factor RelB isoform X3 [KO:K09253]
118386036  transcription factor RelB-like isoform X1 [KO:K09253]
Compound
C00076  Calcium cation
C00165  Diacylglycerol
C00338  Lipopolysaccharide
C00575  3',5'-Cyclic AMP
C01245  D-myo-Inositol 1,4,5-trisphosphate
Reference
PMID:11749383
  Authors
Chen Z, Gibson TB, Robinson F, Silvestro L, Pearson G, Xu B, Wright A, Vanderbilt C, Cobb MH.
  Title
MAP kinases.
  Journal
Chem Rev 101:2449-76 (2001)
DOI:10.1021/cr000241p
Reference
PMID:12191611
  Authors
Tanoue T, Nishida E.
  Title
Docking interactions in the mitogen-activated protein kinase cascades.
  Journal
Pharmacol Ther 93:193-202 (2002)
DOI:10.1016/S0163-7258(02)00188-2
Reference
PMID:12947395
  Authors
Dent P, Yacoub A, Fisher PB, Hagan MP, Grant S.
  Title
MAPK pathways in radiation responses.
  Journal
Oncogene 22:5885-96 (2003)
DOI:10.1038/sj.onc.1206701
Reference
PMID:12676795
  Authors
Huang EJ, Reichardt LF.
  Title
Trk receptors: roles in neuronal signal transduction.
  Journal
Annu Rev Biochem 72:609-42 (2003)
DOI:10.1146/annurev.biochem.72.121801.161629
Reference
PMID:11369511
  Authors
Harper SJ, LoGrasso P.
  Title
Signalling for survival and death in neurones: the role of stress-activated kinases, JNK and p38.
  Journal
Cell Signal 13:299-310 (2001)
DOI:10.1016/S0898-6568(01)00148-6
Reference
PMID:12390245
  Authors
Takeda K, Ichijo H
  Title
Neuronal p38 MAPK signalling: an emerging regulator of cell fate and function in the nervous system.
  Journal
Genes Cells 7:1099-111 (2002)
DOI:10.1046/j.1365-2443.2002.00591.x
Reference
PMID:14597384
  Authors
Yang SH, Sharrocks AD, Whitmarsh AJ.
  Title
Transcriptional regulation by the MAP kinase signaling cascades.
  Journal
Gene 320:3-21 (2003)
DOI:10.1016/S0378-1119(03)00816-3
Reference
PMID:12566928
  Authors
Zhu X, Lee HG, Raina AK, Perry G, Smith MA.
  Title
The role of mitogen-activated protein kinase pathways in Alzheimer's disease.
  Journal
Neurosignals 11:270-81 (2002)
DOI:10.1159/000067426
Reference
PMID:12849693
  Authors
Cho H, Lee J, Kwak NJ, Lee KH, Rha S, Kim YH, Cho YY, Yang KH, Kim K, Lim Y.
  Title
Silica induces nuclear factor-kappaB activation through TAK1 and NIK in Rat2 cell line.
  Journal
Toxicol Lett 143:323-30 (2003)
DOI:10.1016/S0378-4274(03)00193-0
Reference
PMID:20602996
  Authors
Lemmon MA, Schlessinger J
  Title
Cell signaling by receptor tyrosine kinases.
  Journal
Cell 141:1117-34 (2010)
DOI:10.1016/j.cell.2010.06.011
Reference
PMID:22367796
  Authors
Skaper SD
  Title
The neurotrophin family of neurotrophic factors: an overview.
  Journal
Methods Mol Biol 846:1-12 (2012)
DOI:10.1007/978-1-61779-536-7_1
Reference
PMID:23085193
  Authors
Chu WM
  Title
Tumor necrosis factor.
  Journal
Cancer Lett 328:222-5 (2013)
DOI:10.1016/j.canlet.2012.10.014
Reference
PMID:22296764
  Authors
Newton K, Dixit VM
  Title
Signaling in innate immunity and inflammation.
  Journal
Cold Spring Harb Perspect Biol 4:a006049 (2012)
DOI:10.1101/cshperspect.a006049
Reference
PMID:19483709
  Authors
Gaestel M, Kotlyarov A, Kracht M
  Title
Targeting innate immunity protein kinase signalling in inflammation.
  Journal
Nat Rev Drug Discov 8:480-99 (2009)
DOI:10.1038/nrd2829
Reference
PMID:23664135
  Authors
Ajibade AA, Wang HY, Wang RF
  Title
Cell type-specific function of TAK1 in innate immune signaling.
  Journal
Trends Immunol 34:307-16 (2013)
DOI:10.1016/j.it.2013.03.007
Reference
PMID:24892271
  Authors
Turner MD, Nedjai B, Hurst T, Pennington DJ
  Title
Cytokines and chemokines: At the crossroads of cell signalling and inflammatory disease.
  Journal
Biochim Biophys Acta 1843:2563-2582 (2014)
DOI:10.1016/j.bbamcr.2014.05.014
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