KEGG Orthology (KO) - Ictalurus punctatus (channel catfish)

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     KO
 09100 Metabolism
 
   09101 Carbohydrate metabolism
 
   09102 Energy metabolism
 
   09103 Lipid metabolism
     00061 Fatty acid biosynthesis [PATH:ipu00061]
     00062 Fatty acid elongation [PATH:ipu00062]
     00071 Fatty acid degradation [PATH:ipu00071]
     00072 Synthesis and degradation of ketone bodies [PATH:ipu00072]
     00073 Cutin, suberine and wax biosynthesis
     00100 Steroid biosynthesis [PATH:ipu00100]
     00120 Primary bile acid biosynthesis [PATH:ipu00120]
     00121 Secondary bile acid biosynthesis
     00140 Steroid hormone biosynthesis [PATH:ipu00140]
     00561 Glycerolipid metabolism [PATH:ipu00561]
     00564 Glycerophospholipid metabolism [PATH:ipu00564]
     00565 Ether lipid metabolism [PATH:ipu00565]
     00600 Sphingolipid metabolism [PATH:ipu00600]
     00590 Arachidonic acid metabolism [PATH:ipu00590]
       108263034 pla2g12b; phospholipase A2 group XIIB
       108277191 group 3 secretory phospholipase A2-like
       108255707 group 3 secretory phospholipase A2-like
       108263807 Pla2g12a; group XIIA secretory phospholipase A2-like
       108264938 acidic phospholipase A2 1-like
       108277361 pla2g1b; phospholipase A2 group IB
       108258821 group 10 secretory phospholipase A2-like
       108256767 group 10 secretory phospholipase A2-like
       108278205 uncharacterized LOC108278205
       108277761 pla2g4a; phospholipase A2 group IVA
       108257972 cytosolic phospholipase A2-like
       108269587 cytosolic phospholipase A2 zeta-like
       108270284 cytosolic phospholipase A2 zeta-like
       108270285 cytosolic phospholipase A2 zeta-like
       108259399 pla2g6; phospholipase A2 group VI
       108257774 phospholipase B1
       108269596 phospholipase B1
       108269896 phospholipase B1
       108257913 phospholipase B1
       108269055 HRAS-like suppressor 3
       108255976 prostaglandin G/H synthase 1-like
       108277762 prostaglandin G/H synthase 2-like
       108257974 PTGS2; prostaglandin G/H synthase 2-like
       108277763 prostaglandin G/H synthase 2-like
       108259917 ptges; prostaglandin E synthase
       108265283 ptges2; prostaglandin E synthase 2
       100528333 ptges3; prostaglandin E synthase 3
       108279390 carbonyl reductase [NADPH] 1-like
       108258607 cbr1; carbonyl reductase 1
       108254989 fam213b; family with sequence similarity 213 member B
       108264404 tbxas1; thromboxane A synthase 1
       108276825 lcn2; lipocalin 2
       100528611 gst28; glutathione S-transferase class-mu 28 kda isozyme
       108271893 prostacyclin synthase-like
       108272147 ptgis; prostaglandin I2 synthase
       108263823 alox5; arachidonate 5-lipoxygenase
       108279936 lta4h; leukotriene A4 hydrolase
       108274321 CYP4F66; docosahexaenoic acid omega-hydroxylase CYP4F3-like
       108268577 ltc4s; leukotriene C4 synthase
       108277203 gamma-glutamyltranspeptidase 1-like
       108277204 gamma-glutamyltransferase 5-like
       108257088 gamma-glutamyltranspeptidase 1-like
       108264900 gamma-glutamyltranspeptidase 1-like
       108264903 gamma-glutamyltranspeptidase 1-like
       108264906 gamma-glutamyltranspeptidase 1-like
       108264907 gamma-glutamyltransferase 5-like
       108273566 glutathione peroxidase 6-like
       108255192 glutathione peroxidase 1-like
       108264935 gpx8; glutathione peroxidase 8 (putative)
       108269632 gpx2; glutathione peroxidase 2
       100528471 gpx1; glutathione peroxidase 1
       108276007 gpx7; glutathione peroxidase 7
       108274952 gpx3; glutathione peroxidase 3
       108257767 cytochrome P450 2J2-like
       108262960 cytochrome P450 2U1
       108270338 ephx2; epoxide hydrolase 2
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16343 PLA2G6; calcium-independent phospholipase A2 [EC:3.1.1.4]
K14621 PLB1; phospholipase B1, membrane-associated [EC:3.1.1.4 3.1.1.5]
K14621 PLB1; phospholipase B1, membrane-associated [EC:3.1.1.4 3.1.1.5]
K14621 PLB1; phospholipase B1, membrane-associated [EC:3.1.1.4 3.1.1.5]
K14621 PLB1; phospholipase B1, membrane-associated [EC:3.1.1.4 3.1.1.5]
K16817 PLA2G16; HRAS-like suppressor 3 [EC:3.1.1.32 3.1.1.4]
K00509 PTGS1; prostaglandin-endoperoxide synthase 1 [EC:1.14.99.1]
K11987 PTGS2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K11987 PTGS2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K11987 PTGS2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K15729 PTGES; microsomal prostaglandin-E synthase 1 [EC:5.3.99.3]
K05309 PTGES2; microsomal prostaglandin-E synthase 2 [EC:5.3.99.3]
K15730 PTGES3; cytosolic prostaglandin-E synthase [EC:5.3.99.3]
K00079 CBR1; carbonyl reductase 1 [EC:1.1.1.184 1.1.1.189 1.1.1.197]
K00079 CBR1; carbonyl reductase 1 [EC:1.1.1.184 1.1.1.189 1.1.1.197]
K15717 PRXL2B; prostamide/prostaglandin F2alpha synthase [EC:1.11.1.20]
K01832 TBXAS1; thromboxane-A synthase [EC:5.3.99.5]
K01830 PTGDS; prostaglandin-H2 D-isomerase [EC:5.3.99.2]
K04097 HPGDS; prostaglandin-H2 D-isomerase / glutathione transferase [EC:5.3.99.2 2.5.1.18]
K01831 PTGIS; prostacyclin synthase [EC:5.3.99.4]
K01831 PTGIS; prostacyclin synthase [EC:5.3.99.4]
K00461 ALOX5; arachidonate 5-lipoxygenase [EC:1.13.11.34]
K01254 LTA4H; leukotriene-A4 hydrolase [EC:3.3.2.6]
K17726 CYP4F2_3; phylloquinone omega-hydroxylase / docosahexaenoic acid omega-hydroxylase / leukotriene-B4 20-monooxygenase [EC:1.14.14.78 1.14.14.79 1.14.14.94]
K00807 LTC4S; leukotriene-C4 synthase [EC:4.4.1.20]
K18592 GGT1_5; gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14]
K18592 GGT1_5; gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14]
K18592 GGT1_5; gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14]
K18592 GGT1_5; gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14]
K18592 GGT1_5; gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14]
K18592 GGT1_5; gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14]
K18592 GGT1_5; gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14]
K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
K07418 CYP2J; cytochrome P450 family 2 subfamily J [EC:1.14.14.1 1.14.14.73 1.14.14.74 1.14.14.75]
K07422 CYP2U1; cytochrome P450 family 2 subfamily U polypeptide 1
K08726 EPHX2; soluble epoxide hydrolase / lipid-phosphate phosphatase [EC:3.3.2.10 3.1.3.76]
     00591 Linoleic acid metabolism [PATH:ipu00591]
     00592 alpha-Linolenic acid metabolism [PATH:ipu00592]
     01040 Biosynthesis of unsaturated fatty acids [PATH:ipu01040]
 
   09104 Nucleotide metabolism
 
   09105 Amino acid metabolism
 
   09106 Metabolism of other amino acids
 
   09107 Glycan biosynthesis and metabolism
 
   09108 Metabolism of cofactors and vitamins
 
   09109 Metabolism of terpenoids and polyketides
 
   09110 Biosynthesis of other secondary metabolites
 
   09111 Xenobiotics biodegradation and metabolism
 
   09112 Not included in regular maps
 
 09120 Genetic Information Processing
 
 09130 Environmental Information Processing
 
   09131 Membrane transport
 
   09132 Signal transduction
     02020 Two-component system
     04014 Ras signaling pathway
     04015 Rap1 signaling pathway
     04010 MAPK signaling pathway [PATH:ipu04010]
     04013 MAPK signaling pathway - fly
     04016 MAPK signaling pathway - plant
     04011 MAPK signaling pathway - yeast
     04012 ErbB signaling pathway [PATH:ipu04012]
     04310 Wnt signaling pathway [PATH:ipu04310]
     04330 Notch signaling pathway [PATH:ipu04330]
     04340 Hedgehog signaling pathway [PATH:ipu04340]
     04341 Hedgehog signaling pathway - fly
     04350 TGF-beta signaling pathway [PATH:ipu04350]
     04390 Hippo signaling pathway
     04391 Hippo signaling pathway - fly
     04392 Hippo signaling pathway - multiple species
     04370 VEGF signaling pathway [PATH:ipu04370]
       108268977 vascular endothelial growth factor A-like
       108279200 vascular endothelial growth factor A-like
       108280002 vegfa; vascular endothelial growth factor A
       108280865 vascular endothelial growth factor A-A-like
       108258084 kdr; kinase insert domain receptor
       108273196 uncharacterized LOC108273196
       108275796 plcg1; phospholipase C gamma 1
       108264222 plcg2; phospholipase C gamma 2
       108259727 protein kinase C alpha type-like
       108273127 prkca; protein kinase C alpha
       108258960 protein kinase C beta type-like
       108260780 protein kinase C beta type
       108266582 protein kinase C gamma type-like
       108264213 sphk2; sphingosine kinase 2
       108273191 sphk1; sphingosine kinase 1
       108272828 sphingosine kinase 1-like
       100528230 hras; HRas proto-oncogene, GTPase
       108259582 GTPase HRas
       108258948 H-RAS; GTPase HRas-like
       108274959 GTPase KRas
       100305071 nras; neuroblastoma RAS viral oncogene homolog
       108276324 RAF1; RAF proto-oncogene serine/threonine-protein kinase-like
       108255012 raf1; Raf-1 proto-oncogene, serine/threonine kinase
       108264753 map2k1; mitogen-activated protein kinase kinase 1
       100528123 mp2k2; dual specificity mitogen-activated protein kinase kinase 2
       108271291 dual specificity mitogen-activated protein kinase kinase 2
       108255782 mapk1; mitogen-activated protein kinase 1
       108256206 mitogen-activated protein kinase 1-like
       108277761 pla2g4a; phospholipase A2 group IVA
       108257972 cytosolic phospholipase A2-like
       108269587 cytosolic phospholipase A2 zeta-like
       108270284 cytosolic phospholipase A2 zeta-like
       108270285 cytosolic phospholipase A2 zeta-like
       108276890 serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform-like
       108255714 PPP3CC; serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform-like
       108267763 ppp3ca; protein phosphatase 3 catalytic subunit alpha
       108274683 serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform-like
       108278499 serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform-like
       108263224 ppp3r1; protein phosphatase 3 regulatory subunit B, alpha
       108258530 calcineurin subunit B type 1
       108271764 nuclear factor of activated T-cells
       108276420 nfatc2; nuclear factor of activated T-cells 2
       108277762 prostaglandin G/H synthase 2-like
       108257974 PTGS2; prostaglandin G/H synthase 2-like
       108277763 prostaglandin G/H synthase 2-like
       108267913 focal adhesion kinase 1-like
       108256909 ptk2; protein tyrosine kinase 2
       108270761 shc2; SHC adaptor protein 2
       108265853 leupaxin-like
       108265409 uncharacterized LOC108265409
       108276251 cell division control protein 42 homolog
       100528978 cdc42; cell division cycle 42
       108272678 cell division control protein 42 homolog
       108254806 mapk14a; mitogen-activated protein kinase 14A-like
       108264559 MK12; mitogen-activated protein kinase 12
       108265696 mitogen-activated protein kinase 13-like
       108279456 MAPK11; mitogen-activated protein kinase 11-like
       108276094 mitogen-activated protein kinase 12-like
       108265726 mitogen-activated protein kinase 14A
       108279513 mitogen-activated protein kinase 12-like
       108255116 mapkapk2; mitogen-activated protein kinase-activated protein kinase 2
       108281044 MAP kinase-activated protein kinase 3-like
       108260422 hspb1; heat shock protein family B (small) member 1
       108260309 heat shock protein beta-1-like
       108255075 proto-oncogene tyrosine-protein kinase Src-like
       108276199 src; proto-oncogene tyrosine-protein kinase Src
       108275608 phosphatidylinositol 4
       108280664 pik3cb; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
       108271155 pik3ca; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
       108276156 pik3cd; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
       108272037 pik3r3; phosphoinositide-3-kinase regulatory subunit 3
       108260231 pik3r1; phosphoinositide-3-kinase regulatory subunit 1
       108273830 ras-related C3 botulinum toxin substrate 1-like
       108257150 Rac1; ras-related C3 botulinum toxin substrate 1
       108276437 ras-related C3 botulinum toxin substrate 2
       108259609 rac3; ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
       108263416 akt3; AKT serine/threonine kinase 3
       108264340 AKT2; RAC-beta serine/threonine-protein kinase
       108269621 akt1; AKT serine/threonine kinase 1
       108259077 RAC-gamma serine/threonine-protein kinase-like
       108276164 casp9; caspase 9
       108278747 bad; BCL2 associated agonist of cell death
       108267538 P100/11E; bcl2-associated agonist of cell death-like
K05448 VEGFA; vascular endothelial growth factor A
K05448 VEGFA; vascular endothelial growth factor A
K05448 VEGFA; vascular endothelial growth factor A
K05448 VEGFA; vascular endothelial growth factor A
K05098 KDR; kinase insert domain protein receptor [EC:2.7.10.1]
K08273 SH2D2A; SH2 domain protein 2A
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04718 SPHK; sphingosine kinase [EC:2.7.1.91]
K04718 SPHK; sphingosine kinase [EC:2.7.1.91]
K04718 SPHK; sphingosine kinase [EC:2.7.1.91]
K02833 HRAS; GTPase HRas
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K17332 NFATC2; nuclear factor of activated T-cells, cytoplasmic 2
K17332 NFATC2; nuclear factor of activated T-cells, cytoplasmic 2
K11987 PTGS2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K11987 PTGS2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K11987 PTGS2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
K17447 SHC2; SHC-transforming protein 2
K05760 PXN; paxillin
K05760 PXN; paxillin
K04393 CDC42; cell division control protein 42
K04393 CDC42; cell division control protein 42
K04393 CDC42; cell division control protein 42
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04443 MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
K04444 MAPKAPK3; mitogen-activated protein kinase-activated protein kinase 3 [EC:2.7.11.1]
K04455 HSPB1; heat shock protein beta-1
K04455 HSPB1; heat shock protein beta-1
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02158 BAD; Bcl-2-antagonist of cell death
K02158 BAD; Bcl-2-antagonist of cell death
     04371 Apelin signaling pathway [PATH:ipu04371]
     04630 Jak-STAT signaling pathway
     04064 NF-kappa B signaling pathway
     04668 TNF signaling pathway
     04066 HIF-1 signaling pathway
     04068 FoxO signaling pathway [PATH:ipu04068]
     04020 Calcium signaling pathway [PATH:ipu04020]
     04070 Phosphatidylinositol signaling system [PATH:ipu04070]
     04072 Phospholipase D signaling pathway
     04071 Sphingolipid signaling pathway
     04024 cAMP signaling pathway
     04022 cGMP-PKG signaling pathway
     04151 PI3K-Akt signaling pathway
     04152 AMPK signaling pathway
     04150 mTOR signaling pathway [PATH:ipu04150]
     04075 Plant hormone signal transduction
 
   09133 Signaling molecules and interaction
 
 09140 Cellular Processes
 
 09150 Organismal Systems
 
   09151 Immune system
     04640 Hematopoietic cell lineage
     04610 Complement and coagulation cascades
     04611 Platelet activation
     04620 Toll-like receptor signaling pathway [PATH:ipu04620]
     04624 Toll and Imd signaling pathway
     04621 NOD-like receptor signaling pathway [PATH:ipu04621]
     04622 RIG-I-like receptor signaling pathway [PATH:ipu04622]
     04623 Cytosolic DNA-sensing pathway [PATH:ipu04623]
     04625 C-type lectin receptor signaling pathway [PATH:ipu04625]
       100528230 hras; HRas proto-oncogene, GTPase
       108259582 GTPase HRas
       108258948 H-RAS; GTPase HRas-like
       108274959 GTPase KRas
       100305071 nras; neuroblastoma RAS viral oncogene homolog
       100528485 rasm; ras-related protein m-ras
       108266255 MRAS; ras-related protein M-Ras
       108271356 rras2; related RAS viral (r-ras) oncogene homolog 2
       108280565 rras; related RAS viral (r-ras) oncogene homolog
       108276324 RAF1; RAF proto-oncogene serine/threonine-protein kinase-like
       108255012 raf1; Raf-1 proto-oncogene, serine/threonine kinase
       108260779 putative transcription factor p65 homolog
       108277838 relb; RELB proto-oncogene, NF-kB subunit
       108267859 interleukin-12 subunit alpha-like
       108280274 uncharacterized LOC108280274
       108264170 interleukin-12 subunit beta-like
       108278485 il12b; interleukin 12B
       100304696 il1b; interleukin 1, beta
       100304697 il1b; interleukin 1, beta
       108277200 syk; spleen associated tyrosine kinase
       108276278 PTPN11; tyrosine-protein phosphatase non-receptor type 11-like
       108277290 ptpn11; protein tyrosine phosphatase, non-receptor type 11
       108263809 mitogen-activated protein kinase kinase kinase 14-like
       108259239 mitogen-activated protein kinase kinase kinase 14-like
       108263650 chuk; conserved helix-loop-helix ubiquitous kinase
       108263483 nfkb2; nuclear factor kappa B subunit 2
       108264222 plcg2; phospholipase C gamma 2
       108254919 itpr1; inositol 1,4,5-trisphosphate receptor type 1
       108271603 inositol 1
       108264307 itpr2; inositol 1,4,5-trisphosphate receptor type 2
       108265736 itpr3; inositol 1,4,5-trisphosphate receptor type 3
       108270185 myosin light chain 1/3
       108277932 calm3; calmodulin 3
       108279128 calmodulin
       100305090 calm2; calmodulin 2
       108263280 CALM; calmodulin
       100528973 calml4; calmodulin like 4
       108258233 CALM; calmodulin
       100528746 calml6; calmodulin like 6
       108276890 serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform-like
       108255714 PPP3CC; serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform-like
       108267763 ppp3ca; protein phosphatase 3 catalytic subunit alpha
       108274683 serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform-like
       108278499 serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform-like
       108263224 ppp3r1; protein phosphatase 3 regulatory subunit B, alpha
       108258530 calcineurin subunit B type 1
       108280571 NFATC1; nuclear factor of activated T-cells, cytoplasmic 1-like
       108257496 nfatc1; nuclear factor of activated T-cells 1
       108271764 nuclear factor of activated T-cells
       108276420 nfatc2; nuclear factor of activated T-cells 2
       108274982 nuclear factor of activated T-cells
       108259262 nfatc3; nuclear factor of activated T-cells 3
       108267600 nfatc4; nuclear factor of activated T-cells 4
       108255115 il10; interleukin 10
       108273427 egr2; early growth response 2
       108269483 early growth response protein 2b-like
       108265748 egr3; early growth response 3
       108277762 prostaglandin G/H synthase 2-like
       108257974 PTGS2; prostaglandin G/H synthase 2-like
       108277763 prostaglandin G/H synthase 2-like
       108254977 protein kinase C delta type-like
       108271968 protein kinase C delta type-like
       108255782 mapk1; mitogen-activated protein kinase 1
       108256206 mitogen-activated protein kinase 1-like
       108261175 NACHT
       108266868 NACHT
       108280423 NACHT
       108261292 NACHT
       108280623 NACHT
       108265197 NACHT
       108263642 NACHT
       108270753 NACHT
       108257668 NACHT
       100526730 uncharacterized LOC100526730
       108267794 CASP1; caspase-4-like
       108255884 card9; caspase recruitment domain family member 9
       108268257 bcl10; B-cell CLL/lymphoma 10
       108270956 mucosa-associated lymphoid tissue lymphoma translocation protein 1-like
       108255999 malt1; MALT1 paracaspase
       108273098 caspase-8-like
       108273129 caspase-8-like
       108278050 caspase-8-like
       108275953 ikbkg; inhibitor of nuclear factor kappa B kinase subunit gamma
       108265675 ikbkb; inhibitor of nuclear factor kappa B kinase subunit beta
       108269796 nfkbia; NFKB inhibitor alpha
       108258222 Nfkbia; NF-kappa-B inhibitor alpha-like
       108277163 nfkb1; nuclear factor kappa B subunit 1
       100304592 tnf; tumor necrosis factor
       108257494 il6; interleukin 6
       108275681 interleukin-23 subunit alpha-like
       108254806 mapk14a; mitogen-activated protein kinase 14A-like
       108264559 MK12; mitogen-activated protein kinase 12
       108265696 mitogen-activated protein kinase 13-like
       108279456 MAPK11; mitogen-activated protein kinase 11-like
       108276094 mitogen-activated protein kinase 12-like
       108265726 mitogen-activated protein kinase 14A
       108279513 mitogen-activated protein kinase 12-like
       108278622 mapk9; mitogen-activated protein kinase 9
       108274025 mitogen-activated protein kinase 8
       108263675 mapk8b; mitogen-activated protein kinase 8
       108278438 mitogen-activated protein kinase 10-like
       108267848 JUN; transcription factor AP-1-like
       108258130 jun; Jun proto-oncogene, AP-1 transcription factor subunit
       108260086 transcription factor AP-1-like
       108276857 cblb; Cbl proto-oncogene B
       100305060 IgE receptor gamma
       100304589 FcR gamma subunit
       108273733 C-type lectin domain family 4 member M-like
       108266556 CD209 antigen-like protein E
       108261984 CD209 antigen-like protein C
       108260059 rho guanine nucleotide exchange factor 12-like
       108271788 Rhoa; rho-related GTP-binding protein RhoA-D-like
       108275781 rho-related GTP-binding protein RhoA-C
       108265463 rho-related GTP-binding protein RhoA-A
       108254710 transforming protein RhoA-like
       108265880 rho-related GTP-binding protein RhoA-B
       100528424 rhoc; rho-related gtp-binding protein rhoc
       108264802 pak1; p21 (RAC1) activated kinase 1
       108277235 ksr1; kinase suppressor of ras 1
       108277690 kinase suppressor of Ras 1-like
       108268125 plk3; polo like kinase 3
       108255075 proto-oncogene tyrosine-protein kinase Src-like
       108276199 src; proto-oncogene tyrosine-protein kinase Src
       108255225 ikbke; inhibitor of nuclear factor kappa B kinase subunit epsilon
       108266311 STAT1; signal transducer and activator of transcription 1-like
       108259490 signal transducer and activator of transcription 1-alpha/beta-like
       108273876 irf9; interferon regulatory factor 9
       108267044 il17d; interleukin 17D
       108259656 cyld; CYLD lysine 63 deubiquitinase
       108260805 ubiquitin carboxyl-terminal hydrolase CYLD-like
       108271977 ubiquitin carboxyl-terminal hydrolase CYLD-like
       108269240 B-cell lymphoma 3 protein-like
       108255116 mapkapk2; mitogen-activated protein kinase-activated protein kinase 2
       108260738 C-type lectin domain family 4 member M-like
       108260742 C-type lectin domain family 4 member E-like
       108272893 C-type lectin domain family 4 member E-like
       108274476 hepatic lectin-like
       108275608 phosphatidylinositol 4
       108280664 pik3cb; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
       108271155 pik3ca; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
       108276156 pik3cd; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
       108272037 pik3r3; phosphoinositide-3-kinase regulatory subunit 3
       108260231 pik3r1; phosphoinositide-3-kinase regulatory subunit 1
       108263416 akt3; AKT serine/threonine kinase 3
       108264340 AKT2; RAC-beta serine/threonine-protein kinase
       108269621 akt1; AKT serine/threonine kinase 1
       108259077 RAC-gamma serine/threonine-protein kinase-like
       108279728 mdm2; MDM2 proto-oncogene
       108278857 interferon regulatory factor 1-like
K02833 HRAS; GTPase HRas
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K07831 MRAS; Ras-related protein M-Ras
K07831 MRAS; Ras-related protein M-Ras
K07830 RRAS2; Ras-related protein R-Ras2
K07830 RRAS2; Ras-related protein R-Ras2
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04735 RELA; transcription factor p65
K09253 RELB; transcription factor RelB
K05406 IL12A; interleukin 12A
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05425 IL12B; interleukin 12B
K04519 IL1B; interleukin 1 beta
K04519 IL1B; interleukin 1 beta
K05855 SYK; spleen tyrosine kinase [EC:2.7.10.2]
K07293 PTPN11; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K07293 PTPN11; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K04466 MAP3K14; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
K04466 MAP3K14; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K04469 NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K04446 NFATC1; nuclear factor of activated T-cells, cytoplasmic 1
K04446 NFATC1; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2; nuclear factor of activated T-cells, cytoplasmic 2
K17332 NFATC2; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3; nuclear factor of activated T-cells, cytoplasmic 3
K17333 NFATC3; nuclear factor of activated T-cells, cytoplasmic 3
K17334 NFATC4; nuclear factor of activated T-cells, cytoplasmic 4
K05443 IL10; interleukin 10
K12496 EGR2; early growth response protein 2
K12496 EGR2; early growth response protein 2
K12497 EGR3; early growth response protein 3
K11987 PTGS2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K11987 PTGS2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K11987 PTGS2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K06068 PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
K06068 PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K12800 NLRP3; NACHT, LRR and PYD domains-containing protein 3
K12800 NLRP3; NACHT, LRR and PYD domains-containing protein 3
K12800 NLRP3; NACHT, LRR and PYD domains-containing protein 3
K12800 NLRP3; NACHT, LRR and PYD domains-containing protein 3
K12800 NLRP3; NACHT, LRR and PYD domains-containing protein 3
K12800 NLRP3; NACHT, LRR and PYD domains-containing protein 3
K12800 NLRP3; NACHT, LRR and PYD domains-containing protein 3
K12800 NLRP3; NACHT, LRR and PYD domains-containing protein 3
K12800 NLRP3; NACHT, LRR and PYD domains-containing protein 3
K12800 NLRP3; NACHT, LRR and PYD domains-containing protein 3
K01370 CASP1; caspase 1 [EC:3.4.22.36]
K12794 CARD9; caspase recruitment domain-containing protein 9
K07368 BCL10; B-cell CLL/lymphoma 10
K07369 MALT1; mucosa-associated lymphoid tissue lymphoma translocation protein 1 [EC:3.4.22.-]
K07369 MALT1; mucosa-associated lymphoid tissue lymphoma translocation protein 1 [EC:3.4.22.-]
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K03156 TNF; tumor necrosis factor superfamily, member 2
K05405 IL6; interleukin 6
K05426 IL23A; interleukin 23 subunit alpha
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04448 JUN; transcription factor AP-1
K04448 JUN; transcription factor AP-1
K22517 CBLB; E3 ubiquitin-protein ligase CBL-B [EC:2.3.2.27]
K07983 FCER1G; high affinity immunoglobulin epsilon receptor subunit gamma
K07983 FCER1G; high affinity immunoglobulin epsilon receptor subunit gamma
K06563 CLEC4M; C-type lectin domain family 4 member M
K06563 CLEC4M; C-type lectin domain family 4 member M
K06563 CLEC4M; C-type lectin domain family 4 member M
K07532 ARHGEF12; Rho guanine nucleotide exchange factor 12
K04513 RHOA; Ras homolog gene family, member A
K04513 RHOA; Ras homolog gene family, member A
K04513 RHOA; Ras homolog gene family, member A
K04513 RHOA; Ras homolog gene family, member A
K04513 RHOA; Ras homolog gene family, member A
K04513 RHOA; Ras homolog gene family, member A
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K14958 KSR1; kinase suppressor of Ras 1
K14958 KSR1; kinase suppressor of Ras 1
K08862 PLK3; polo-like kinase 3 [EC:2.7.11.21]
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K07211 IKBKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
K11220 STAT1; signal transducer and activator of transcription 1
K11220 STAT1; signal transducer and activator of transcription 1
K04693 IRF9; interferon regulatory factor 9
K05492 IL17D; interleukin 17D
K08601 CYLD; ubiquitin carboxyl-terminal hydrolase CYLD [EC:3.4.19.12]
K08601 CYLD; ubiquitin carboxyl-terminal hydrolase CYLD [EC:3.4.19.12]
K08601 CYLD; ubiquitin carboxyl-terminal hydrolase CYLD [EC:3.4.19.12]
K09258 BCL3; B-cell CLL/lymphoma protein 3
K04443 MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
K10059 CLEC4E; C-type lectin domain family 4 member E
K10059 CLEC4E; C-type lectin domain family 4 member E
K10059 CLEC4E; C-type lectin domain family 4 member E
K10059 CLEC4E; C-type lectin domain family 4 member E
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K09444 IRF1; interferon regulatory factor 1
     04650 Natural killer cell mediated cytotoxicity
     04612 Antigen processing and presentation
     04660 T cell receptor signaling pathway
     04658 Th1 and Th2 cell differentiation
     04659 Th17 cell differentiation
     04657 IL-17 signaling pathway
     04662 B cell receptor signaling pathway
     04664 Fc epsilon RI signaling pathway
     04666 Fc gamma R-mediated phagocytosis
     04670 Leukocyte transendothelial migration
     04672 Intestinal immune network for IgA production [PATH:ipu04672]
     04062 Chemokine signaling pathway
 
   09152 Endocrine system
 
   09153 Circulatory system
 
   09154 Digestive system
 
   09155 Excretory system
 
   09156 Nervous system
 
   09157 Sensory system
 
   09158 Development and regeneration
 
   09149 Aging
 
   09159 Environmental adaptation
 
 09160 Human Diseases
 
 09180 Brite Hierarchies
 
 09190 Not Included in Pathway or Brite

[ KO | BRITE | KEGG2 | KEGG ]
Last updated: February 18, 2020