KEGG   PATHWAY: otw05168
Entry
otw05168                    Pathway                                
Name
Herpes simplex virus 1 infection - Oncorhynchus tshawytscha (Chinook salmon)
Description
Herpes simplex virus 1(HSV-1) is a common human pathogen, which initially infects orofacial mucosal surfaces. The virus replicates in epithelial cells at these sites, causing clinically overt disease characterized by vesicular lesions. HSV-1 then penetrates to the nervous system and establishes latency in sensory neurons. Throughout the lifetime of the host, HSV-1 may reactivate from its latent state and reinitiate a lytic infection cycle. HSV-1 has developed various mechanisms to escape its host innate immune responses and increased its capacity to replicate and to persist. ICP34.5, ICP0, ICP27, Us11 and Vhs (UL41) are the proteins involved in viral interference.
Class
Human Diseases; Infectious disease: viral
Pathway map
otw05168  Herpes simplex virus 1 infection
otw05168

Organism
Oncorhynchus tshawytscha (Chinook salmon) [GN:otw]
Gene
112226201  tnfsf14; tumor necrosis factor ligand superfamily member 14 [KO:K05477]
112226208  tumor necrosis factor ligand superfamily member 14 [KO:K05477]
121843483  tumor necrosis factor ligand superfamily member 14 [KO:K05477]
112235187  tumor necrosis factor receptor superfamily member 14 isoform X1 [KO:K05152]
112235188  tumor necrosis factor receptor superfamily member 14-like [KO:K05152]
112235190  LOW QUALITY PROTEIN: tumor necrosis factor receptor superfamily member 14 [KO:K05152]
112235192  tumor necrosis factor receptor superfamily member 14 isoform X1 [KO:K05152]
112235197  tumor necrosis factor receptor superfamily member 14 [KO:K05152]
112235184  tumor necrosis factor receptor superfamily member 14-like [KO:K05152]
112235193  tumor necrosis factor receptor superfamily member 14-like [KO:K05152]
112235196  tumor necrosis factor receptor superfamily member 14-like isoform X1 [KO:K05152]
112242846  tumor necrosis factor receptor superfamily member 14-like isoform X1 [KO:K05152]
112220313  TNF receptor-associated factor 2-like [KO:K03173] [EC:2.3.2.27]
112248690  traf2a; TNF receptor-associated factor 2 isoform X1 [KO:K03173] [EC:2.3.2.27]
112230792  TNF receptor-associated factor 2 isoform X1 [KO:K03173] [EC:2.3.2.27]
112220413  traf2b; TNF receptor-associated factor 2 isoform X1 [KO:K03173] [EC:2.3.2.27]
112230971  TNF receptor-associated factor 2-like isoform X1 [KO:K03173] [EC:2.3.2.27]
112230449  traf5; TNF receptor-associated factor 5 isoform X1 [KO:K09849]
112265814  TNF receptor-associated factor 5-like isoform X1 [KO:K09849]
112263933  ikbkb; inhibitor of nuclear factor kappa-B kinase subunit beta [KO:K07209] [EC:2.7.11.10]
112223895  inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1 [KO:K04467] [EC:2.7.11.10]
112224128  inhibitor of nuclear factor kappa-B kinase subunit alpha [KO:K04467] [EC:2.7.11.10]
112223622  inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1 [KO:K04467] [EC:2.7.11.10]
121840490  NF-kappa-B essential modulator-like [KO:K07210]
112221359  ikbkg; LOW QUALITY PROTEIN: NF-kappa-B essential modulator [KO:K07210]
112239880  NF-kappa-B essential modulator isoform X1 [KO:K07210]
112249975  NF-kappa-B inhibitor alpha [KO:K04734]
112244922  NF-kappa-B inhibitor alpha isoform X1 [KO:K04734]
112256803  nfkbiab; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b [KO:K04734]
112217446  NF-kappa-B inhibitor alpha [KO:K04734]
112220841  nfkb1; nuclear factor NF-kappa-B p105 subunit [KO:K02580]
112256149  nuclear factor NF-kappa-B p105 subunit-like [KO:K02580]
112260059  transcription factor p65 [KO:K04735]
112214775  putative transcription factor p65 homolog isoform X1 [KO:K04735]
112235685  inhibitor of apoptosis protein-like [KO:K16060]
112246336  baculoviral IAP repeat-containing protein 2-like isoform X1 [KO:K16060]
112267832  nectin-1-like [KO:K06081]
112225433  nectin-4 isoform X1 [KO:K06081]
112262758  nectin-3-like isoform X1 [KO:K06081]
112238700  nectin-1 [KO:K06081]
112217987  nectin-1-like [KO:K06081]
112247864  nectin-1-like isoform X1 [KO:K06081]
112244584  si:ch73-22o12.1; poliovirus receptor isoform X1 [KO:K06531]
112229823  poliovirus receptor-like isoform X1 [KO:K06531]
112264802  poliovirus receptor [KO:K06531]
112228268  poliovirus receptor isoform X1 [KO:K06531]
112257482  tyrosine-protein phosphatase non-receptor type 11 isoform X1 [KO:K07293] [EC:3.1.3.48]
112221573  tyrosine-protein phosphatase non-receptor type 11 isoform X1 [KO:K07293] [EC:3.1.3.48]
112219594  tyrosine-protein phosphatase non-receptor type 11 isoform X1 [KO:K07293] [EC:3.1.3.48]
112233022  tyrosine-protein phosphatase non-receptor type 11 isoform X1 [KO:K07293] [EC:3.1.3.48]
112246216  integrin alpha-5-like isoform X1 [KO:K06484]
112267689  integrin alpha-5 [KO:K06484]
112215221  integrin alpha-5 [KO:K06484]
112221831  LOW QUALITY PROTEIN: integrin alpha-5-like [KO:K06484]
112223770  itgb3b; integrin beta-3 isoform X1 [KO:K06493]
112258603  integrin beta-3 [KO:K06493]
112225975  integrin beta-3-like [KO:K06493]
112255048  proto-oncogene tyrosine-protein kinase Src isoform X1 [KO:K05704] [EC:2.7.10.2]
112221781  src; proto-oncogene tyrosine-protein kinase Src isoform X1 [KO:K05704] [EC:2.7.10.2]
112267038  proto-oncogene tyrosine-protein kinase Src isoform X1 [KO:K05704] [EC:2.7.10.2]
112216306  proto-oncogene tyrosine-protein kinase Src isoform X1 [KO:K05704] [EC:2.7.10.2]
112219981  syk; tyrosine-protein kinase SYK isoform X1 [KO:K05855] [EC:2.7.10.2]
112263304  caspase recruitment domain-containing protein 9 [KO:K12794]
112247679  caspase recruitment domain-containing protein 9-like isoform X1 [KO:K12794]
112235560  irf3; interferon regulatory factor 3 isoform X1 [KO:K05411]
112260048  cellular tumor antigen p53 [KO:K04451]
112214763  cellular tumor antigen p53 isoform X1 [KO:K04451]
112229014  tp53; cellular tumor antigen p53 [KO:K04451]
112246076  complement C3 [KO:K03990]
112246089  complement C3-like [KO:K03990]
112246615  complement C3-like [KO:K03990]
112248904  c5; complement C5 [KO:K03994]
112232601  properdin-like [KO:K15412]
112222051  cfp; properdin [KO:K15412]
112237807  tlr2; toll-like receptor 2 type-2 [KO:K10159]
112229323  tlr18; toll-like receptor 18 [KO:K10159]
112227606  myd88; myeloid differentiation primary response protein MyD88 [KO:K04729]
112252506  interferon regulatory factor 7-like [KO:K09447]
112218673  interferon regulatory factor 8 [KO:K09447]
112231807  tlr3; toll-like receptor 3 [KO:K05401]
112221602  ticam1; TIR domain-containing adapter molecule 1 [KO:K05842]
112218414  interleukin-1 receptor-associated kinase 4 [KO:K04733] [EC:2.7.11.1]
112238306  irak1; interleukin-1 receptor-associated kinase 1 isoform X1 [KO:K04730] [EC:2.7.11.1]
112247822  traf6; TNF receptor-associated factor 6 [KO:K03175] [EC:2.3.2.27]
112261976  mitogen-activated protein kinase kinase kinase 7 [KO:K04427] [EC:2.7.11.25]
112217513  mitogen-activated protein kinase kinase kinase 7-like isoform X2 [KO:K04427] [EC:2.7.11.25]
112256531  mitogen-activated protein kinase kinase kinase 7 [KO:K04427] [EC:2.7.11.25]
112250048  mitogen-activated protein kinase kinase kinase 7 isoform X1 [KO:K04427] [EC:2.7.11.25]
112241134  LOW QUALITY PROTEIN: TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 [KO:K04403]
121843572  TGF-beta-activated kinase 1 and MAP3K7-binding protein 1-like [KO:K04403]
112250087  TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 isoform X1 [KO:K04404]
112217538  TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 isoform X1 [KO:K04404]
112248882  interleukin-1 beta [KO:K04519]
112219797  il1b; interleukin-1 beta isoform X1 [KO:K04519]
112230772  interleukin-1 beta [KO:K04519]
121847916  interleukin-1 beta-like [KO:K04519]
121847917  interleukin-1 beta-like [KO:K04519]
112262548  interleukin-1 beta-like [KO:K04519]
121838769  interleukin-1 beta-like [KO:K04519]
112235861  il6; interleukin-6 [KO:K05405]
112264462  interleukin-6-like isoform X1 [KO:K05405]
112245031  tumor necrosis factor [KO:K03156]
112238602  tumor necrosis factor [KO:K03156]
112230200  tumor necrosis factor [KO:K03156]
112247217  tumor necrosis factor-like [KO:K03156]
112267572  uncharacterized protein LOC112267572 [KO:K05406]
112244633  interleukin-12 subunit alpha [KO:K05406]
112258298  il12bb; interleukin-12 subunit beta [KO:K05425]
112235249  interleukin-12 subunit beta [KO:K05425]
112228305  interleukin-12 subunit beta [KO:K05425]
112235243  interleukin-12 subunit beta-like [KO:K05425]
112235857  si:dkey-88e18.2; interleukin-12 subunit beta isoform X1 [KO:K05425]
112239684  ddx58; LOW QUALITY PROTEIN: probable ATP-dependent RNA helicase DDX58 [KO:K12646] [EC:5.6.2.6]
112225192  ifih1; interferon-induced helicase C domain-containing protein 1 [KO:K12647] [EC:5.6.2.6]
112236223  proline-rich protein 36 [KO:K12648]
112244941  traf3; TNF receptor-associated factor 3 [KO:K03174]
112256827  TNF receptor-associated factor 3-like [KO:K03174]
112244673  ikbke; inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform X1 [KO:K07211] [EC:2.7.11.10]
112240934  serine/threonine-protein kinase TBK1-like [KO:K05410] [EC:2.7.11.10]
112242097  serine/threonine-protein kinase TBK1-like [KO:K05410] [EC:2.7.11.10]
112259408  interferon a3-like [KO:K05414]
112258504  interferon a3-like [KO:K05414]
112258505  interferon tau-6 [KO:K05414]
112259172  interferon a3-like [KO:K05414]
112258507  interferon a3 isoform X1 [KO:K05414]
112258508  interferon a3 isoform X1 [KO:K05414]
112258510  interferon beta-like [KO:K05414]
112258512  interferon a3-like [KO:K05414]
112259401  interferon alpha-1-like [KO:K05414]
112259402  interferon alpha-13-like [KO:K05414]
112259403  interferon a3-like [KO:K05414]
112259404  interferon beta-like [KO:K05414]
112259405  interferon a3-like [KO:K05414]
112259406  interferon a3-like [KO:K05414]
112225813  interferon alpha-3-like [KO:K05414]
112225814  interferon beta-like [KO:K05414]
112225815  interferon beta-like [KO:K05414]
112225816  interferon a3 isoform X1 [KO:K05414]
112223801  ifnphi4; interferon phi 4 isoform X1 [KO:K05414]
121847201  interferon beta-like [KO:K05414]
121847202  interferon beta-like [KO:K05414]
121847204  interferon a3-like [KO:K05414]
121847206  interferon a3-like [KO:K05414]
121847315  interferon a3-like [KO:K05414]
121847317  interferon a3-like [KO:K05414]
121841054  LOW QUALITY PROTEIN: interferon omega-1-like [KO:K05414]
121841055  LOW QUALITY PROTEIN: interferon omega-1-like [KO:K05414]
121841056  LOW QUALITY PROTEIN: interferon omega-1-like [KO:K05414]
121841057  LOW QUALITY PROTEIN: interferon omega-1-like [KO:K05414]
121841106  interferon beta-like [KO:K05414]
121841114  interferon beta-like [KO:K05414]
121841115  interferon beta-like [KO:K05414]
121841118  interferon beta-like [KO:K05414]
121841120  interferon beta-like [KO:K05414]
121841121  interferon beta-like [KO:K05414]
121841123  interferon beta-like [KO:K05414]
112258514  interferon a3-like [KO:K05414]
121847316  interferon a3-like [KO:K05414]
121847318  interferon a3-like [KO:K05414]
112254417  cyclic GMP-AMP synthase [KO:K17834] [EC:2.7.7.86]
112229902  cyclic GMP-AMP synthase [KO:K17834] [EC:2.7.7.86]
112264864  cyclic GMP-AMP synthase isoform X1 [KO:K17834] [EC:2.7.7.86]
112253530  cgasa; LOW QUALITY PROTEIN: cyclic GMP-AMP synthase [KO:K17834] [EC:2.7.7.86]
112255958  stimulator of interferon genes protein [KO:K12654]
112221185  stimulator of interferon genes protein-like [KO:K12654]
112259017  serine/threonine-protein phosphatase alpha-2 isoform [KO:K06269] [EC:3.1.3.16]
112248359  serine/threonine-protein phosphatase PP1-gamma catalytic subunit A [KO:K06269] [EC:3.1.3.16]
112223856  ppp1cab; protein phosphatase 1, catalytic subunit, alpha isozyme b [KO:K06269] [EC:3.1.3.16]
112260058  serine/threonine-protein phosphatase PP1-beta catalytic subunit isoform X1 [KO:K06269] [EC:3.1.3.16]
112250506  serine/threonine-protein phosphatase PP1-beta catalytic subunit-like [KO:K06269] [EC:3.1.3.16]
112258985  serine/threonine-protein phosphatase alpha-2 isoform [KO:K06269] [EC:3.1.3.16]
112217890  serine/threonine-protein phosphatase PP1-beta catalytic subunit [KO:K06269] [EC:3.1.3.16]
112214774  serine/threonine-protein phosphatase PP1-beta catalytic subunit isoform X1 [KO:K06269] [EC:3.1.3.16]
112263044  serine/threonine-protein phosphatase PP1-gamma catalytic subunit A [KO:K06269] [EC:3.1.3.16]
112259470  eif2ak1; eukaryotic translation initiation factor 2-alpha kinase 1 isoform X1 [KO:K16194] [EC:2.7.11.1]
112253229  eif2ak2; interferon-induced, double-stranded RNA-activated protein kinase isoform X1 [KO:K16195] [EC:2.7.11.1]
112236837  eif2ak3; eukaryotic translation initiation factor 2-alpha kinase 3 [KO:K08860] [EC:2.7.11.1]
112261826  eif2ak4; eIF-2-alpha kinase GCN2 [KO:K16196] [EC:2.7.11.1]
112255754  LOW QUALITY PROTEIN: eIF-2-alpha kinase GCN2-like [KO:K16196] [EC:2.7.11.1]
112250468  eukaryotic translation initiation factor 2 subunit 1 [KO:K03237]
112261564  eukaryotic translation initiation factor 2 subunit 1 [KO:K03237]
112256881  eif2s1a; eukaryotic translation initiation factor 2 subunit 1a [KO:K03237]
112257480  translation initiation factor eIF-2B subunit alpha isoform X1 [KO:K03239]
112262886  translation initiation factor eIF-2B subunit alpha [KO:K03239]
112235304  translation initiation factor eIF-2B subunit beta [KO:K03754]
112236225  translation initiation factor eIF-2B subunit beta-like [KO:K03754]
121844091  LOW QUALITY PROTEIN: translation initiation factor eIF-2B subunit beta-like [KO:K03754]
112260462  translation initiation factor eIF-2B subunit gamma [KO:K03241]
112226946  eif2b3; translation initiation factor eIF-2B subunit gamma [KO:K03241]
112217964  eif2b4; translation initiation factor eIF-2B subunit delta [KO:K03680]
112249873  translation initiation factor eIF-2B subunit delta-like [KO:K03680]
112260921  eif2b5; translation initiation factor eIF-2B subunit epsilon [KO:K03240]
112238307  host cell factor 1 [KO:K14966]
112254372  host cell factor 1 isoform X1 [KO:K14966]
112219915  host cell factor 1 isoform X1 [KO:K14966]
112215272  hcfc1b; LOW QUALITY PROTEIN: host cell factor 1b [KO:K14966]
112216924  host cell factor 2 isoform X1 [KO:K27390]
112215021  host cell factor 2-like [KO:K27390]
112242335  POU domain, class 2, transcription factor 1 isoform X1 [KO:K09364]
112258059  POU domain, class 2, transcription factor 3-like isoform X1 [KO:K09364]
112235815  POU domain, class 2, transcription factor 2 isoform X1 [KO:K09364]
112243600  POU domain, class 2, transcription factor 1 isoform X1 [KO:K09364]
112225343  pou2f1b; POU domain, class 2, transcription factor 1 isoform X1 [KO:K09364]
112266025  POU domain, class 2, transcription factor 2-like [KO:K09364]
112228370  pou2f3; POU domain, class 2, transcription factor 3 [KO:K09364]
112229349  LOW QUALITY PROTEIN: POU domain, class 2, transcription factor 2 [KO:K09364]
112239098  pou2f2a; POU domain, class 2, transcription factor 2 isoform X1 [KO:K09364]
112225266  interferon alpha/beta receptor 2 isoform X1 [KO:K05131]
112243175  uncharacterized protein LOC112243175 [KO:K05131]
112226342  suppressor of cytokine signaling 3 [KO:K04696]
112229883  suppressor of cytokine signaling 3 [KO:K04696]
112257362  suppressor of cytokine signaling 3 [KO:K04696]
121845826  suppressor of cytokine signaling 3-like [KO:K04696]
112234778  jak1; tyrosine-protein kinase JAK1 [KO:K11217] [EC:2.7.10.2]
112260228  tyrosine-protein kinase JAK1 [KO:K11217] [EC:2.7.10.2]
112227154  tyrosine-protein kinase JAK1 isoform X1 [KO:K11217] [EC:2.7.10.2]
112250666  tyrosine-protein kinase JAK1-like isoform X1 [KO:K11217] [EC:2.7.10.2]
112226073  non-receptor tyrosine-protein kinase TYK2 [KO:K11219] [EC:2.7.10.2]
112258691  non-receptor tyrosine-protein kinase TYK2 [KO:K11219] [EC:2.7.10.2]
112253897  signal transducer and activator of transcription 1-alpha/beta isoform X1 [KO:K11220]
112244575  stat1b; signal transducer and activator of transcription 1b [KO:K11220]
112235369  signal transducer and activator of transcription 1-alpha/beta isoform X3 [KO:K11220]
112253955  signal transducer and activator of transcription 1-alpha/beta isoform X1 [KO:K11220]
112253779  signal transducer and activator of transcription 1-alpha/beta [KO:K11220]
112217577  stat2; signal transducer and activator of transcription 2 isoform X1 [KO:K11221]
112233598  interferon regulatory factor 8 isoform X1 [KO:K04693]
112234069  irf9; interferon regulatory factor 9 [KO:K04693]
112230434  zinc finger protein 501-like isoform X1 [KO:K09228]
112239675  zinc finger protein 501 isoform X1 [KO:K09228]
112248067  oocyte zinc finger protein XlCOF22 [KO:K09228]
121839957  zinc finger and SCAN domain-containing protein 2-like [KO:K09228]
121844145  zinc finger protein 180-like isoform X1 [KO:K09228]
121844165  zinc finger protein 239-like [KO:K09228]
112238000  zinc finger protein 501 isoform X1 [KO:K09228]
112238001  LOW QUALITY PROTEIN: gastrula zinc finger protein XlCGF17.1 [KO:K09228]
112229839  uncharacterized protein LOC112229839 [KO:K09228]
112230071  zinc finger protein 239 [KO:K09228]
112245056  zinc finger protein 239-like [KO:K09228]
112245057  zinc finger protein 501-like [KO:K09228]
112245060  zinc finger protein 664-like [KO:K09228]
112245064  zinc finger protein 664-like [KO:K09228]
112245065  zinc finger protein 2 homolog [KO:K09228]
112245073  zinc finger protein 2 homolog [KO:K09228]
112229414  zinc finger protein 501 isoform X1 [KO:K09228]
112241143  zinc finger protein 665 isoform X1 [KO:K09228]
112261622  zinc finger protein 770 isoform X1 [KO:K09228]
112253591  oocyte zinc finger protein XlCOF6 [KO:K09228]
112239108  zinc finger protein 501-like [KO:K09228]
112246545  zinc finger and SCAN domain-containing protein 2-like [KO:K09228]
112261008  zinc finger protein 436 [KO:K09228]
112262143  zinc finger protein 585A [KO:K09228]
112263120  zinc finger protein 37 [KO:K09228]
112224384  zinc finger protein 420-like [KO:K09228]
112224386  zinc finger protein 845-like isoform X1 [KO:K09228]
112263292  LOW QUALITY PROTEIN: zinc finger protein 721 [KO:K09228]
112237904  zinc finger protein 420 [KO:K09228]
112240710  zinc finger protein 883-like [KO:K09228]
112242102  zinc finger protein 135-like [KO:K09228]
112239568  zinc finger protein 239-like [KO:K09228]
112240301  oocyte zinc finger protein XlCOF19-like [KO:K09228]
112240302  gastrula zinc finger protein XlCGF17.1 isoform X1 [KO:K09228]
112241679  LOW QUALITY PROTEIN: zinc finger protein 436 [KO:K09228]
112253705  zinc finger protein 585A isoform X1 [KO:K09228]
112253706  zinc finger protein 791 [KO:K09228]
112253708  zinc finger protein 271 [KO:K09228]
112253709  oocyte zinc finger protein XlCOF6-like isoform X1 [KO:K09228]
112253755  zinc finger protein 239-like [KO:K09228]
112250435  zinc finger protein 436 isoform X1 [KO:K09228]
112220023  zinc finger protein 883-like isoform X1 [KO:K09228]
112230815  zinc finger protein 239-like [KO:K09228]
112217283  zinc finger protein 239-like [KO:K09228]
112230427  zinc finger protein 436-like [KO:K09228]
112230428  zinc finger protein OZF-like [KO:K09228]
112230431  zinc finger protein 2 homolog isoform X1 [KO:K09228]
112266410  gastrula zinc finger protein XlCGF26.1 isoform X3 [KO:K09228]
112266411  zinc finger protein 708 isoform X1 [KO:K09228]
112265310  gastrula zinc finger protein XlCGF26.1 isoform X1 [KO:K09228]
112248065  uncharacterized protein LOC112248065 isoform X1 [KO:K09228]
112248066  oocyte zinc finger protein XlCOF6-like [KO:K09228]
112237146  gastrula zinc finger protein XlCGF26.1-like [KO:K09228]
112239850  zinc finger protein 501-like [KO:K09228]
112239851  zinc finger protein 180-like [KO:K09228]
112239864  zinc finger protein 239-like [KO:K09228]
112239865  zinc finger protein 501-like [KO:K09228]
112254072  zinc finger protein 2 homolog [KO:K09228]
112254080  zinc finger protein OZF-like [KO:K09228]
112255150  zinc finger protein OZF-like [KO:K09228]
112240365  gastrula zinc finger protein XlCGF17.1-like [KO:K09228]
112241747  gastrula zinc finger protein XlCGF26.1-like [KO:K09228]
112247631  zinc finger protein 271 isoform X1 [KO:K09228]
112247632  zinc finger protein 239 [KO:K09228]
112261473  zinc finger protein 420 [KO:K09228]
112251201  oocyte zinc finger protein XlCOF6 [KO:K09228]
112266896  gastrula zinc finger protein XlCGF26.1 isoform X1 [KO:K09228]
112266897  gastrula zinc finger protein XlCGF26.1 [KO:K09228]
112214714  zinc finger protein 11-like [KO:K09228]
112230165  zinc finger protein 54 isoform X1 [KO:K09228]
112230168  zinc finger protein 883 [KO:K09228]
112265494  oocyte zinc finger protein XlCOF6 [KO:K09228]
112242184  zinc finger protein 345 [KO:K09228]
112242185  zinc finger protein 2-like [KO:K09228]
112242186  gastrula zinc finger protein XlCGF26.1-like [KO:K09228]
112248004  LOW QUALITY PROTEIN: zinc finger protein 135 [KO:K09228]
112248005  zinc finger protein 2 homolog [KO:K09228]
112258277  zinc finger protein 11 isoform X1 [KO:K09228]
112258289  zinc finger protein 14 [KO:K09228]
112260796  uncharacterized protein LOC112260796 [KO:K09228]
112239676  zinc finger protein 2-like isoform X1 [KO:K09228]
112241021  zinc finger protein 883-like [KO:K09228]
112241034  zinc finger protein 239-like [KO:K09228]
112250492  zinc finger protein 770-like [KO:K09228]
112251313  oocyte zinc finger protein XlCOF6 [KO:K09228]
112254466  zinc finger protein 239-like [KO:K09228]
112240077  zinc finger protein 2 homolog [KO:K09228]
112255222  gastrula zinc finger protein XlCGF57.1-like [KO:K09228]
112256780  zinc finger protein 770 [KO:K09228]
112257882  zinc finger protein 664-like [KO:K09228]
112257883  zinc finger protein OZF-like [KO:K09228]
112223769  zinc finger protein 664-like [KO:K09228]
112223780  zinc finger protein 845 isoform X1 [KO:K09228]
112238570  zinc finger protein 883 [KO:K09228]
112238571  zinc finger protein 883 [KO:K09228]
112239912  zinc finger protein 239-like [KO:K09228]
112239224  zinc finger protein 135 isoform X1 [KO:K09228]
112240589  zinc finger protein 2 homolog isoform X1 [KO:K09228]
112231440  zinc finger protein 345 [KO:K09228]
112220600  zinc finger protein OZF-like isoform X1 [KO:K09228]
112220597  zinc finger protein 664-like [KO:K09228]
112239080  zinc finger protein 239 isoform X2 [KO:K09228]
112240450  gastrula zinc finger protein XlCGF57.1 [KO:K09228]
112240468  zinc finger protein 501-like isoform X1 [KO:K09228]
112254923  zinc finger protein 493 [KO:K09228]
112261999  gastrula zinc finger protein XlCGF57.1 isoform X1 [KO:K09228]
112264535  zinc finger protein 239-like isoform X1 [KO:K09228]
112264542  zinc finger and SCAN domain-containing protein 2-like isoform X1 [KO:K09228]
112259990  zinc finger protein 501 [KO:K09228]
112215696  zinc finger protein OZF [KO:K09228]
112219128  zinc finger protein 287 [KO:K09228]
112226428  zinc finger protein ZFMSA12A isoform X1 [KO:K09228]
112244828  zinc finger and SCAN domain-containing protein 2 [KO:K09228]
112259457  zinc finger protein OZF-like [KO:K09228]
112260018  zinc finger protein 169 [KO:K09228]
112214579  zinc finger protein 501 [KO:K09228]
112220418  oocyte zinc finger protein XlCOF6 isoform X1 [KO:K09228]
112226507  gastrula zinc finger protein XlCGF57.1 isoform X1 [KO:K09228]
112242647  zinc finger protein 2 homolog [KO:K09228]
112251054  zinc finger protein 502 [KO:K09228]
112251581  endothelial zinc finger protein induced by tumor necrosis factor alpha-like [KO:K09228]
112252258  zinc finger protein 708 [KO:K09228]
112215832  zinc finger protein 33A isoform X1 [KO:K09228]
112226573  zinc finger protein 420 isoform X1 [KO:K09228]
112231283  zinc finger protein 777 [KO:K09228]
112248514  zinc finger protein 397 isoform X1 [KO:K09228]
112254086  zinc finger protein 79-like [KO:K09228]
112266490  gastrula zinc finger protein XlCGF46.1 [KO:K09228]
112266491  zinc finger protein 723 isoform X1 [KO:K09228]
112214689  oocyte zinc finger protein XlCOF6 [KO:K09228]
112230170  oocyte zinc finger protein XlCOF22 isoform X1 [KO:K09228]
112238772  oocyte zinc finger protein XlCOF6.1 [KO:K09228]
112238773  zinc finger protein 271 isoform X1 [KO:K09228]
112241459  zinc finger protein 501 [KO:K09228]
112254687  gastrula zinc finger protein XlCGF58.1 isoform X13 [KO:K09228]
112267153  zinc finger protein 2 isoform X1 [KO:K09228]
112214723  zinc finger protein 2 [KO:K09228]
112227930  zinc finger protein with KRAB and SCAN domains 7 [KO:K09228]
112241577  uncharacterized protein LOC112241577 isoform X1 [KO:K09228]
112260109  zinc finger protein OZF-like isoform X1 [KO:K09228]
112260110  zinc finger protein 664-like [KO:K09228]
112263140  zinc finger protein 239 [KO:K09228]
112217225  gastrula zinc finger protein XlCGF17.1-like [KO:K09228]
112224372  gastrula zinc finger protein XlCGF57.1-like [KO:K09228]
112224388  zinc finger protein 888-like [KO:K09228]
112226769  uncharacterized protein LOC112226769 isoform X1 [KO:K09228]
112227996  zinc finger protein 300 [KO:K09228]
112240296  gastrula zinc finger protein XlCGF57.1 [KO:K09228]
112240297  zinc finger protein 501-like isoform X2 [KO:K09228]
112241678  zinc finger protein 436 [KO:K09228]
112244037  zinc finger protein OZF [KO:K09228]
112253707  oocyte zinc finger protein XlCOF6-like [KO:K09228]
112230429  zinc finger protein 2 homolog isoform X1 [KO:K09228]
112230432  zinc finger protein 271-like [KO:K09228]
112239018  zinc finger and SCAN domain-containing protein 2-like isoform X1 [KO:K09228]
112239020  zinc finger protein 558-like [KO:K09228]
112243039  zinc finger protein 501 [KO:K09228]
112255506  zinc finger protein 664 [KO:K09228]
112255598  zinc finger protein 2 homolog [KO:K09228]
112256263  zinc finger protein 37-like [KO:K09228]
112220965  zinc finger protein 37 [KO:K09228]
112223360  oocyte zinc finger protein XlCOF6 isoform X2 [KO:K09228]
112235207  zinc finger protein OZF [KO:K09228]
112239021  zinc finger protein OZF [KO:K09228]
112239022  zinc finger protein 883-like isoform X1 [KO:K09228]
112240448  zinc finger protein 2-like [KO:K09228]
112264540  zinc finger protein ZFMSA12A-like [KO:K09228]
112264541  oocyte zinc finger protein XlCOF22-like isoform X2 [KO:K09228]
112264768  oocyte zinc finger protein XlCOF6.1 isoform X1 [KO:K09228]
112265576  uncharacterized protein LOC112265576 [KO:K09228]
112266237  gastrula zinc finger protein XlCGF26.1 [KO:K09228]
112266345  zinc finger protein 239 [KO:K09228]
112229364  zinc finger protein 2 homolog isoform X1 [KO:K09228]
112229376  oocyte zinc finger protein XlCOF6 [KO:K09228]
112229432  zinc finger protein 345 [KO:K09228]
112231797  gastrula zinc finger protein XlCGF57.1 [KO:K09228]
112234050  zinc finger protein 271 [KO:K09228]
112219911  zinc finger protein 501-like [KO:K09228]
112222195  zinc finger protein with KRAB and SCAN domains 8 [KO:K09228]
112224670  zinc finger protein 664 isoform X1 [KO:K09228]
112229445  gastrula zinc finger protein XlCGF57.1 [KO:K09228]
112248980  zinc finger protein 501 [KO:K09228]
112256526  zinc finger protein OZF isoform X1 [KO:K09228]
112230764  zinc finger protein 883-like [KO:K09228]
112234227  oocyte zinc finger protein XlCOF22-like isoform X1 [KO:K09228]
112234228  zinc finger protein ZFMSA12A-like [KO:K09228]
112237907  gastrula zinc finger protein XlCGF26.1 [KO:K09228]
112240719  gastrula zinc finger protein XlCGF57.1 [KO:K09228]
112242128  gastrula zinc finger protein XlCGF26.1-like [KO:K09228]
112246694  zinc finger protein with KRAB and SCAN domains 8 [KO:K09228]
112220019  oocyte zinc finger protein XlCOF6 isoform X1 [KO:K09228]
112220022  zinc finger protein 665 isoform X1 [KO:K09228]
112221228  zinc finger and SCAN domain-containing protein 12 isoform X1 [KO:K09228]
112227208  gastrula zinc finger protein xFG20-1 isoform X2 [KO:K09228]
112230808  zinc finger protein OZF-like [KO:K09228]
112245623  zinc finger protein 75A-like [KO:K09228]
112248006  zinc finger protein 708-like [KO:K09228]
112257879  zinc finger protein OZF [KO:K09228]
112258449  zinc finger and SCAN domain-containing protein 31 [KO:K09228]
112259689  zinc finger protein 37 isoform X1 [KO:K09228]
112259691  zinc finger protein OZF isoform X22 [KO:K09228]
112259695  zinc finger protein 8-like isoform X1 [KO:K09228]
112216453  gastrula zinc finger protein XlCGF58.1 isoform X1 [KO:K09228]
112223741  zinc finger protein 239-like [KO:K09228]
112227244  zinc finger protein 418 [KO:K09228]
112239474  zinc finger protein 135 isoform X1 [KO:K09228]
112256664  zinc finger protein OZF [KO:K09228]
112259701  zinc finger protein 250-like [KO:K09228]
112259705  zinc finger protein 182-like isoform X4 [KO:K09228]
112220173  zinc finger protein 501-like [KO:K09228]
112239608  zinc finger protein OZF [KO:K09228]
112242350  zinc finger protein 709 [KO:K09228]
112246945  zinc finger protein Xfin [KO:K09228]
112258333  zinc finger protein 287 isoform X1 [KO:K09228]
112221429  zinc finger protein 2 [KO:K09228]
112226216  zinc finger protein 2 isoform X1 [KO:K09228]
112226235  gastrula zinc finger protein XlCGF57.1 isoform X1 [KO:K09228]
112236989  oocyte zinc finger protein XlCOF6 [KO:K09228]
112241020  zinc finger protein 883 isoform X1 [KO:K09228]
112260946  zinc finger protein ZFMSA12A isoform X1 [KO:K09228]
112260951  gastrula zinc finger protein XlCGF7.1 [KO:K09228]
112217912  zinc finger protein 770 [KO:K09228]
112222731  gastrula zinc finger protein XlCGF57.1 isoform X1 [KO:K09228]
112222753  uncharacterized protein LOC112222753 isoform X1 [KO:K09228]
112241142  zinc finger protein 135 [KO:K09228]
112226009  zinc finger protein 567 [KO:K09228]
112239017  zinc finger protein OZF-like [KO:K09228]
112241033  zinc finger protein OZF isoform X1 [KO:K09228]
112248002  LOW QUALITY PROTEIN: zinc finger protein 2 [KO:K09228]
112240274  zinc finger protein 664 [KO:K09228]
112234229  zinc finger protein 852-like [KO:K09228]
112226407  uncharacterized protein LOC112226407 isoform X1 [KO:K09228]
112217121  zinc finger protein 585A isoform X1 [KO:K09228]
112238776  zinc finger protein 836 [KO:K09228]
112217120  zinc finger protein 420 [KO:K09228]
112217122  zinc finger protein 14-like isoform X1 [KO:K09228]
112220025  zinc finger protein 665 [KO:K09228]
112222732  gastrula zinc finger protein XlCGF57.1 isoform X1 [KO:K09228]
112226292  gastrula zinc finger protein XlCGF57.1-like [KO:K09228]
112230776  oocyte zinc finger protein XlCOF22-like [KO:K09228]
112264820  zinc finger and SCAN domain-containing protein 20 isoform X1 [KO:K09228]
112266028  zinc finger protein 808 [KO:K09228]
121840611  gastrula zinc finger protein XlCGF57.1-like [KO:K09228]
121840612  gastrula zinc finger protein XlCGF57.1-like isoform X1 [KO:K09228]
121840667  zinc finger protein 26-like isoform X1 [KO:K09228]
121843885  oocyte zinc finger protein XlCOF6-like [KO:K09228]
121845798  zinc finger protein 883-like isoform X1 [KO:K09228]
121841335  oocyte zinc finger protein XlCOF22-like [KO:K09228]
121844470  zinc finger protein 32-like isoform X1 [KO:K09228]
121843790  oocyte zinc finger protein XlCOF6-like [KO:K09228]
112244046  zinc finger protein 227-like [KO:K09228]
121841336  zinc finger protein 227-like [KO:K09228]
121839958  zinc finger protein 664-like [KO:K09228]
112222734  gastrula zinc finger protein XlCGF57.1 [KO:K09228]
112223747  zinc finger protein 625-like [KO:K09228]
112226815  zinc finger protein 271-like [KO:K09228]
112258384  zinc finger protein 3 isoform X1 [KO:K09228]
121842599  zinc finger protein 664-like [KO:K09228]
121845003  zinc finger protein 664-like [KO:K09228]
112237988  ifng1; interferon gamma 1 [KO:K04687]
112224548  interferon gamma receptor 1-like isoform X1 [KO:K05132]
112265249  ifngr1; interferon gamma receptor 1 isoform X1 [KO:K05132]
112224549  interferon gamma receptor 1-like [KO:K05132]
112243284  interleukin-10 receptor subunit beta isoform X1 [KO:K05133]
112225269  uncharacterized protein LOC112225269 [KO:K05133]
112232816  jak2b; tyrosine-protein kinase JAK2 [KO:K04447] [EC:2.7.10.2]
112257378  tyrosine-protein kinase JAK2-like isoform X1 [KO:K04447] [EC:2.7.10.2]
112219669  tyrosine-protein kinase JAK2-like isoform X2 [KO:K04447] [EC:2.7.10.2]
112264793  death domain-associated protein 6-like [KO:K02308]
112233298  death domain-associated protein 6 isoform X1 [KO:K02308]
112222999  antigen peptide transporter 1 [KO:K05653] [EC:7.4.2.14]
112264786  antigen peptide transporter 2-like [KO:K05654] [EC:7.4.2.14]
112223617  tap2t; antigen peptide transporter 2 [KO:K05654] [EC:7.4.2.14]
112229806  antigen peptide transporter 2-like [KO:K05654] [EC:7.4.2.14]
112264792  tapasin [KO:K08058]
112229280  tapasin-like [KO:K08058]
112229742  protein disulfide-isomerase A3 [KO:K08056] [EC:5.3.4.1]
112228742  pdia7; protein disulfide-isomerase A3 [KO:K08056] [EC:5.3.4.1]
112232402  protein disulfide-isomerase A3-like [KO:K08056] [EC:5.3.4.1]
112232997  protein disulfide-isomerase A3 [KO:K08056] [EC:5.3.4.1]
112222193  protein disulfide-isomerase A3 [KO:K08056] [EC:5.3.4.1]
112248178  calr; calreticulin [KO:K08057]
112250789  calreticulin [KO:K08057]
112260371  calreticulin isoform X1 [KO:K08057]
112252190  calreticulin [KO:K08057]
112236584  calr3b; calreticulin 3b [KO:K08057]
112227039  calreticulin [KO:K08057]
112264791  H-2 class I histocompatibility antigen, Q9 alpha chain [KO:K06751]
112267276  major histocompatibility complex class I-related gene protein isoform X1 [KO:K06751]
112233299  major histocompatibility complex class I-related gene protein-like [KO:K06751]
112233300  BOLA class I histocompatibility antigen, alpha chain BL3-7-like [KO:K06751]
112233323  H-2 class I histocompatibility antigen, alpha chain-like [KO:K06751]
112233327  class I histocompatibility antigen, F10 alpha chain-like [KO:K06751]
112234362  LOW QUALITY PROTEIN: major histocompatibility complex class I-related gene protein [KO:K06751]
112264773  class I histocompatibility antigen, F10 alpha chain [KO:K06751]
112264767  major histocompatibility complex class I-related gene protein isoform X2 [KO:K06751]
112264770  H-2 class I histocompatibility antigen, Q10 alpha chain isoform X1 [KO:K06751]
112244620  class I histocompatibility antigen, F10 alpha chain isoform X1 [KO:K06751]
112239310  beta-2-microglobulin [KO:K08055]
112239311  beta-2-microglobulin-like [KO:K08055]
112239312  beta-2-microglobulin-like [KO:K08055]
112222681  H-2 class II histocompatibility antigen, E-S beta chain-like [KO:K06752]
112258050  H-2 class II histocompatibility antigen, A-Q alpha chain-like [KO:K06752]
112258051  HLA class II histocompatibility antigen, DQ beta 1 chain-like isoform X1 [KO:K06752]
112240104  H-2 class II histocompatibility antigen, I-E beta chain-like [KO:K06752]
112240105  H-2 class II histocompatibility antigen, A-U alpha chain [KO:K06752]
112243905  H-2 class II histocompatibility antigen, A-Q alpha chain [KO:K06752]
112220766  H-2 class II histocompatibility antigen gamma chain isoform X1 [KO:K06505]
112256094  HLA class II histocompatibility antigen gamma chain [KO:K06505]
112267269  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
112216060  pik3cd; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
112260202  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
112227144  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
112251044  pik3ca; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
112265788  zgc:158659; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
112266167  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform-like [KO:K00922] [EC:2.7.1.153]
112260699  phosphatidylinositol 3-kinase regulatory subunit gamma [KO:K02649]
112250738  phosphatidylinositol 3-kinase regulatory subunit gamma [KO:K02649]
112260309  phosphatidylinositol 3-kinase regulatory subunit gamma [KO:K02649]
112244626  phosphatidylinositol 3-kinase regulatory subunit gamma isoform X2 [KO:K02649]
112252131  phosphatidylinositol 3-kinase regulatory subunit gamma [KO:K02649]
112226747  phosphatidylinositol 3-kinase regulatory subunit gamma [KO:K02649]
112248937  phosphatidylinositol 3-kinase regulatory subunit alpha [KO:K02649]
112230790  phosphatidylinositol 3-kinase regulatory subunit alpha isoform X2 [KO:K02649]
112234933  phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1 [KO:K02649]
112250872  phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1 [KO:K02649]
112220315  pik3r1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
112250387  RAC-alpha serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
112256640  RAC-alpha serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
112225150  RAC-beta serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
112261841  RAC-alpha serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
112230362  RAC-gamma serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
112265711  akt2; RAC-beta serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
112224566  akt3a; RAC-gamma serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
112265172  RAC-gamma serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
112217662  RAC-alpha serine/threonine-protein kinase isoform X2 [KO:K04456] [EC:2.7.11.1]
112231417  RAC-beta serine/threonine-protein kinase-like [KO:K04456] [EC:2.7.11.1]
112267273  RAC-beta serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
112219359  tsc1b; LOW QUALITY PROTEIN: hamartin [KO:K07206]
112248911  tsc1a; TSC complex subunit 1a isoform X1 [KO:K07206]
112230526  hamartin-like [KO:K07206]
112242265  LOW QUALITY PROTEIN: tuberin [KO:K07207]
112254607  GTP-binding protein Rheb [KO:K07208]
112217539  GTP-binding protein Rheb [KO:K07208]
112247671  GTP-binding protein Rheb isoform X1 [KO:K07208]
112215328  GTP-binding protein Rheb isoform X1 [KO:K07208]
112227773  GTP-binding protein Rheb isoform X1 [KO:K07208]
112241353  GTP-binding protein Rheb-like [KO:K07208]
121843888  GTP-binding protein Rheb-like [KO:K07208]
112215922  mtor; serine/threonine-protein kinase mTOR isoform X1 [KO:K07203] [EC:2.7.11.1]
112248503  eukaryotic translation initiation factor 4E-binding protein 2 [KO:K07205]
112262850  eukaryotic translation initiation factor 4E-binding protein 2 [KO:K07205]
112222400  SRSF protein kinase 1 isoform X1 [KO:K15409] [EC:2.7.11.1]
112263150  SRSF protein kinase 1 [KO:K15409] [EC:2.7.11.1]
112215248  SRSF protein kinase 1 isoform X1 [KO:K15409] [EC:2.7.11.1]
112254162  srpk1b; SRSF protein kinase 1b isoform X1 [KO:K15409] [EC:2.7.11.1]
112267092  LOW QUALITY PROTEIN: serine/arginine-rich splicing factor 1B [KO:K12890]
112265521  serine/arginine-rich splicing factor 1B [KO:K12890]
112230730  serine/arginine-rich splicing factor 1B-like [KO:K12890]
112235686  serine/arginine-rich splicing factor 1B-like [KO:K12890]
112226186  serine/arginine-rich splicing factor 2 isoform X1 [KO:K12891]
112257462  srsf2a; serine and arginine rich splicing factor 2a [KO:K12891]
112229886  serine/arginine-rich splicing factor 2 [KO:K12891]
112235017  serine/arginine-rich splicing factor 2 isoform X1 [KO:K12891]
112234959  LOW QUALITY PROTEIN: serine/arginine-rich splicing factor 2 [KO:K12891]
112217828  srsf3b; serine/arginine-rich splicing factor 3b isoform X1 [KO:K12892]
112254566  serine/arginine-rich splicing factor 3 isoform X1 [KO:K12892]
112254812  serine/arginine-rich splicing factor 3 isoform X1 [KO:K12892]
112215147  serine/arginine-rich splicing factor 3 [KO:K12892]
112260830  serine/arginine-rich splicing factor 6 [KO:K12893]
112215823  serine/arginine-rich splicing factor 6 [KO:K12893]
112236031  serine/arginine-rich splicing factor 5 [KO:K12893]
112264317  serine/arginine-rich splicing factor 4 [KO:K12893]
112235212  serine/arginine-rich splicing factor 5 isoform X1 [KO:K12893]
112222131  serine/arginine-rich splicing factor 6 [KO:K12893]
112256975  serine/arginine-rich splicing factor 5 [KO:K12893]
112247677  srsf5a; serine/arginine-rich splicing factor 5 [KO:K12893]
112258015  serine/arginine-rich splicing factor 7-like [KO:K12896]
112266871  serine/arginine-rich splicing factor 7 isoform X1 [KO:K12896]
112265286  serine/arginine-rich splicing factor 7 isoform X1 [KO:K12896]
112230418  serine/arginine-rich splicing factor 7 isoform X1 [KO:K12896]
112266066  serine/arginine-rich splicing factor 7 isoform X1 [KO:K12896]
112228420  serine/arginine-rich splicing factor 7 isoform X1 [KO:K12896]
112257551  serine/arginine-rich splicing factor 9 [KO:K21123]
112219476  srsf9; serine/arginine-rich splicing factor 9 [KO:K21123]
112248544  serine/arginine-rich splicing factor 9 [KO:K21123]
112228818  nuclear RNA export factor 1 [KO:K14284]
112231326  nuclear RNA export factor 1 [KO:K14284]
112221171  nxf1a; nuclear RNA export factor 1 isoform X1 [KO:K14284]
112245601  THO complex subunit 4 [KO:K12881]
112245839  THO complex subunit 4 [KO:K12881]
112234996  THO complex subunit 4 isoform X1 [KO:K12881]
112234997  THO complex subunit 4-like [KO:K12881]
112251074  tumor necrosis factor ligand superfamily member 6 [KO:K04389]
112248671  tumor necrosis factor ligand superfamily member 6-like isoform X1 [KO:K04389]
112263074  tumor necrosis factor ligand superfamily member 6 [KO:K04389]
112253033  tumor necrosis factor receptor superfamily member 6 isoform X1 [KO:K04390]
112254547  tumor necrosis factor receptor superfamily member 6 isoform X1 [KO:K04390]
112221389  tumor necrosis factor receptor superfamily member 1A [KO:K03158]
112249065  tumor necrosis factor receptor superfamily member 1A isoform X1 [KO:K03158]
112247612  tumor necrosis factor receptor superfamily member 1A [KO:K03158]
112249221  tradd; tumor necrosis factor receptor type 1-associated DEATH domain protein [KO:K03171]
112263724  tumor necrosis factor receptor type 1-associated DEATH domain protein isoform X2 [KO:K03171]
112263517  FAS-associated death domain protein [KO:K02373]
112249032  fadd; protein FADD [KO:K02373]
112226687  casp8; caspase-8 isoform X1 [KO:K04398] [EC:3.4.22.61]
112247430  caspase-8-like isoform X1 [KO:K04398] [EC:3.4.22.61]
112245958  caspase-8 isoform X1 [KO:K04398] [EC:3.4.22.61]
112225661  casp10; caspase-8 isoform X1 [KO:K04398] [EC:3.4.22.61]
112218769  bida; BH3 interacting domain death agonist [KO:K04726]
112251217  apoptosis regulator BAX isoform X1 [KO:K02159]
112258413  apoptosis regulator BAX [KO:K02159]
112246045  apoptosis regulator BAX isoform X1 [KO:K02159]
112226023  apoptosis regulator BAX [KO:K02159]
112263519  apoptosis regulator BAX-like isoform X1 [KO:K02159]
112225734  apoptosis regulator BAX isoform X1 [KO:K02159]
112249035  apoptosis regulator BAX isoform X1 [KO:K02159]
112228809  bada; bcl2-associated agonist of cell death [KO:K02158]
112237949  badb; BCL2 associated agonist of cell death b [KO:K02158]
112227752  apoptosis regulator Bcl-2 [KO:K02161]
112260550  apoptosis regulator Bcl-2 [KO:K02161]
112232698  apoptosis regulator Bcl-2-like [KO:K02161]
112226859  apoptosis regulator Bcl-2 [KO:K02161]
112254374  bcl-2-like protein 1 [KO:K04570]
112215997  bcl-2-like protein 1 isoform X1 [KO:K04570]
112219887  bcl-2-like protein 1 [KO:K04570]
112222374  bcl-2-like protein 1 isoform X1 [KO:K04570]
112245952  cytochrome c [KO:K08738]
112265869  cytochrome c iso-1/iso-2 [KO:K08738]
112225664  cytochrome c [KO:K08738]
112219800  cytochrome c-like [KO:K08738]
112267804  apoptotic protease-activating factor 1 isoform X1 [KO:K02084]
112229243  apaf1; apoptotic protease-activating factor 1 isoform X1 [KO:K02084]
112221816  casp9; caspase-9 [KO:K04399] [EC:3.4.22.62]
112216271  caspase-9 isoform X1 [KO:K04399] [EC:3.4.22.62]
112255992  casp3b; caspase-3b [KO:K02187] [EC:3.4.22.56]
112248666  caspase-3-like [KO:K02187] [EC:3.4.22.56]
112231666  casp3a; caspase-3a [KO:K02187] [EC:3.4.22.56]
112261439  caspase-3 isoform X1 [KO:K02187] [EC:3.4.22.56]
Compound
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C20640  Cyclic GMP-AMP
C20935  2-5A
Reference
PMID:12787566
  Authors
Granger SW, Rickert S
  Title
LIGHT-HVEM signaling and the regulation of T cell-mediated immunity.
  Journal
Cytokine Growth Factor Rev 14:289-96 (2003)
DOI:10.1016/S1359-6101(03)00031-5
Reference
PMID:19495760
  Authors
Steinberg MW, Shui JW, Ware CF, Kronenberg M
  Title
Regulating the mucosal immune system: the contrasting roles of LIGHT, HVEM, and their various partners.
  Journal
Semin Immunopathol 31:207-21 (2009)
DOI:10.1007/s00281-009-0157-4
Reference
PMID:20221426
  Authors
MacLeod IJ, Minson T
  Title
Binding of herpes simplex virus type-1 virions leads to the induction of intracellular signalling in the absence of virus entry.
  Journal
PLoS One 5:e9560 (2010)
DOI:10.1371/journal.pone.0009560
Reference
PMID:23150579
  Authors
Gianni T, Leoni V, Chesnokova LS, Hutt-Fletcher LM, Campadelli-Fiume G
  Title
alphavbeta3-integrin is a major sensor and activator of innate immunity to herpes simplex virus-1.
  Journal
Proc Natl Acad Sci U S A 109:19792-7 (2012)
DOI:10.1073/pnas.1212597109
Reference
PMID:25375272
  Authors
Gianni T, Campadelli-Fiume G
  Title
The epithelial alphavbeta3-integrin boosts the MYD88-dependent TLR2 signaling in response to viral and bacterial components.
  Journal
PLoS Pathog 10:e1004477 (2014)
DOI:10.1371/journal.ppat.1004477
Reference
PMID:15056211
  Authors
Spear PG
  Title
Herpes simplex virus: receptors and ligands for cell entry.
  Journal
Cell Microbiol 6:401-10 (2004)
DOI:10.1111/j.1462-5822.2004.00389.x
Reference
PMID:12855695
  Authors
Boutell C, Everett RD
  Title
The herpes simplex virus type 1 (HSV-1) regulatory protein ICP0 interacts with and Ubiquitinates p53.
  Journal
J Biol Chem 278:36596-602 (2003)
DOI:10.1074/jbc.M300776200
Reference
PMID:24262390
  Authors
Ma Y, He B
  Title
Recognition of herpes simplex viruses: toll-like receptors and beyond.
  Journal
J Mol Biol 426:1133-47 (2014)
DOI:10.1016/j.jmb.2013.11.012
Reference
PMID:26952111
  Authors
Su C, Zhan G, Zheng C
  Title
Evasion of host antiviral innate immunity by HSV-1, an update.
  Journal
Virol J 13:38 (2016)
DOI:10.1186/s12985-016-0495-5
Reference
PMID:21994567
  Authors
Melchjorsen J, Matikainen S, Paludan SR
  Title
Activation and evasion of innate antiviral immunity by herpes simplex virus.
  Journal
Viruses 1:737-59 (2009)
DOI:10.3390/v1030737
Reference
PMID:15276609
  Authors
Morrison LA
  Title
The Toll of herpes simplex virus infection.
  Journal
Trends Microbiol 12:353-6 (2004)
DOI:10.1016/j.tim.2004.06.001
Reference
PMID:29298887
  Authors
Zheng C
  Title
Evasion of Cytosolic DNA-Stimulated Innate Immune Responses by Herpes Simplex Virus 1.
  Journal
J Virol 92:e00099-17 (2018)
DOI:10.1128/JVI.00099-17
Reference
PMID:19344302
  Authors
Grandi P, Peruzzi P, Reinhart B, Cohen JB, Chiocca EA, Glorioso JC
  Title
Design and application of oncolytic HSV vectors for glioblastoma therapy.
  Journal
Expert Rev Neurother 9:505-17 (2009)
DOI:10.1586/ern.09.9
Reference
PMID:23115300
  Authors
Lussignol M, Queval C, Bernet-Camard MF, Cotte-Laffitte J, Beau I, Codogno P, Esclatine A
  Title
The herpes simplex virus 1 Us11 protein inhibits autophagy through its interaction with the protein kinase PKR.
  Journal
J Virol 87:859-71 (2013)
DOI:10.1128/JVI.01158-12
Reference
PMID:17229694
  Authors
Sanchez R, Mohr I
  Title
Inhibition of cellular 2'-5' oligoadenylate synthetase by the herpes simplex virus type 1 Us11 protein.
  Journal
J Virol 81:3455-64 (2007)
DOI:10.1128/JVI.02520-06
Reference
PMID:12826401
  Authors
Wysocka J, Herr W
  Title
The herpes simplex virus VP16-induced complex: the makings of a regulatory switch.
  Journal
Trends Biochem Sci 28:294-304 (2003)
DOI:10.1016/S0968-0004(03)00088-4
Reference
PMID:27367734
  Authors
Fleming SB
  Title
Viral Inhibition of the IFN-Induced JAK/STAT Signalling Pathway: Development of Live Attenuated Vaccines by Mutation of Viral-Encoded IFN-Antagonists.
  Journal
Vaccines (Basel) 4:E23 (2016)
DOI:10.3390/vaccines4030023
Reference
PMID:15163721
  Authors
Yokota S, Yokosawa N, Okabayashi T, Suzutani T, Miura S, Jimbow K, Fujii N
  Title
Induction of suppressor of cytokine signaling-3 by herpes simplex virus type 1 contributes to inhibition of the interferon signaling pathway.
  Journal
J Virol 78:6282-6 (2004)
DOI:10.1128/JVI.78.12.6282-6286.2004
Reference
PMID:23864622
  Authors
Gu H, Zheng Y, Roizman B
  Title
Interaction of herpes simplex virus ICP0 with ND10 bodies: a sequential process of adhesion, fusion, and retention.
  Journal
J Virol 87:10244-54 (2013)
DOI:10.1128/JVI.01487-13
Reference
PMID:21994592
  Authors
Tavalai N, Stamminger T
  Title
Interplay between Herpesvirus Infection and Host Defense by PML Nuclear Bodies.
  Journal
Viruses 1:1240-64 (2009)
DOI:10.3390/v1031240
Reference
PMID:21146386
  Authors
Horst D, Verweij MC, Davison AJ, Ressing ME, Wiertz EJ
  Title
Viral evasion of T cell immunity: ancient mechanisms offering new applications.
  Journal
Curr Opin Immunol 23:96-103 (2011)
DOI:10.1016/j.coi.2010.11.005
Reference
PMID:12960333
  Authors
Neumann J, Eis-Hubinger AM, Koch N
  Title
Herpes simplex virus type 1 targets the MHC class II processing pathway for immune evasion.
  Journal
J Immunol 171:3075-83 (2003)
DOI:10.4049/jimmunol.171.6.3075
Reference
PMID:25798530
  Authors
Liu X, Cohen JI
  Title
The role of PI3K/Akt in human herpesvirus infection: From the bench to the bedside.
  Journal
Virology 479-480:568-77 (2015)
DOI:10.1016/j.virol.2015.02.040
Reference
PMID:28468873
  Authors
Vink EI, Smiley JR, Mohr I
  Title
Subversion of Host Responses to Energy Insufficiency by Us3 Supports Herpes Simplex Virus 1 Replication during Stress.
  Journal
J Virol 91:e00295-17 (2017)
DOI:10.1128/JVI.00295-17
Reference
PMID:18508584
  Authors
Sandri-Goldin RM
  Title
The many roles of the regulatory protein ICP27 during herpes simplex virus infection.
  Journal
Front Biosci 13:5241-56 (2008)
DOI:10.2741/3078
Reference
PMID:15078920
  Authors
Sandri-Goldin RM
  Title
Viral regulation of mRNA export.
  Journal
J Virol 78:4389-96 (2004)
DOI:10.1128/JVI.78.9.4389-4396.2004
Reference
PMID:27154074
  Authors
Yu X, He S
  Title
The interplay between human herpes simplex virus infection and the apoptosis and necroptosis cell death pathways.
  Journal
Virol J 13:77 (2016)
DOI:10.1186/s12985-016-0528-0
Related
pathway
otw03040  Spliceosome
otw03050  Proteasome
otw04115  p53 signaling pathway
otw04210  Apoptosis
otw04620  Toll-like receptor signaling pathway
otw04622  RIG-I-like receptor signaling pathway
KO pathway
ko05168   
LinkDB

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