KEGG ORTHOLOGY: K06838

ORTHOLOGY: K06838

Entry

K06838                      KO

Symbol

SLIT1

Name

slit 1

Pathway

map04360

Axon guidance

map04517

IgSF CAM signaling

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    K06838  SLIT1; slit 1
09150 Organismal Systems
  09158 Development and regeneration
   04360 Axon guidance
    K06838  SLIT1; slit 1
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   00536 Glycosaminoglycan binding proteins
    K06838  SLIT1; slit 1
Glycosaminoglycan binding proteins [BR:ko00536]
Heparan sulfate / Heparin
  Axon guidance molecules
   K06838  SLIT1; slit 1

Genes

HSA:	6585(SLIT1)

PTR:	100609860(SLIT1)

PPS:	100979424(SLIT1)

GGO:	101145008(SLIT1)

PON:	100459557(SLIT1)

PPYG:

129006104(SLIT1)

NLE:	100583873(SLIT1)

HMH:	116456616(SLIT1)

SSYN:

129468283(SLIT1)

MCC:	705901(SLIT1)

MCF:	102114943(SLIT1)

MTHB:

126962064

MNI:	105478454(SLIT1)

CSAB:

103216333(SLIT1)

CATY:

105581783(SLIT1)

PANU:

101008774(SLIT1)

TGE:	112631564(SLIT1)

MLEU:

105554067(SLIT1)

RRO:	104682821(SLIT1)

RBB:	108534585(SLIT1)

TFN:

117069203

PTEH:

111538751(SLIT1)

CANG:

105518277(SLIT1)

CJC:	100406024(SLIT1)

SBQ:	101030686(SLIT1)

CIMI:

108285515(SLIT1)

ANAN:

105708176(SLIT1)

CSYR:

103260100

MMUR:

105872982(SLIT1)

LCAT:

123649731

ERUF:

138376497(SLIT1)

PCOQ:

105818493(SLIT1)

OGA:	100960885(SLIT1)

MMU:	20562(Slit1)

MCAL:

110285289(Slit1)

MPAH:

110329818(Slit1)

RNO:	65047(Slit1)

MCOC:

116103831(Slit1)

ANU:	117709811(Slit1)

ASYL:

127687387(Slit1)

MUN:	110556646(Slit1)

CGE:	100756902(Slit1)

MAUA:

101825700(Slit1)

PROB:

127233301(Slit1)

PLEU:

114706889(Slit1)

PMAV:

102914375(Slit1)

MORG:

121453979(Slit1)

MFOT:

126504604

AAMP:

119818628(Slit1)

CNL:	130879089(Slit1)

NGI:	103733206(Slit1)

HGL:	101722713(Slit1)

CPOC:

100714910(Slit1)

DORD:

105986727(Slit1)

DSP:	122115865(Slit1)

DMER:

138826176 138830117

PLOP:

125346209(Slit1)

NCAR:

124984845

MMMA:

107149935(Slit1)

ITI:	101970575(Slit1)

OCU:

100350940

OPI:	101520316(SLIT1)

OCZ:	121164281(SLIT1)

TUP:	102479497(SLIT1)

GVR:

103603947

CFA:	486818(SLIT1)

CLUD:

112672129(SLIT1)

VVP:	112907665(SLIT1)

VLG:	121485592(SLIT1)

NPO:	129493678(SLIT1)

AML:	100483249(SLIT1)

UMR:	103658831(SLIT1)

UAH:	113251775(SLIT1)

UAR:	123783971(SLIT1)

ELK:

111144820

LLV:

125084542

MPUF:

101676088(SLIT1)

MNP:	132016661(SLIT1)

MLK:	131828596(SLIT1)

NVS:	122900972(SLIT1)

ORO:	101365941(SLIT1)

EJU:	114205272(SLIT1)

ZCA:	113920291(SLIT1)

MLX:	118024355(SLIT1)

MANO:

123846719(SLIT1)

NSU:	110589282(SLIT1)

FCA:	101098258(SLIT1)

PYU:	121037055(SLIT1)

PCOO:

112854325(SLIT1)

PBG:	122493078(SLIT1)

PVIV:

125147612(SLIT1)

LRUF:

124507026

LGF:	123576887(SLIT1)

AJU:

106966925

PTG:	102952150(SLIT1)

PPAD:

109272704(SLIT1)

PUC:

125933144

PLEZ:

122201826(SLIT1)

HHV:	120230570(SLIT1)

CCRU:

144244957(SLIT1)

BTA:	510761(SLIT1)

BOM:	102276091(SLIT1)

BIU:	109578986(SLIT1)

BBUB:

102403465(SLIT1)

BKE:	129636799(SLIT1)

BBIS:

104983583(SLIT1)

CHX:	102169825(SLIT1)

OAS:	101112777(SLIT1)

BTAX:

128067728(SLIT1)

CSUM:

138070197(SLIT1)

ODA:	120873496(SLIT1)

CCAD:

122446079(SLIT1)

MREE:

136158259(SLIT1)

OVR:	110146627(SLIT1)

MBEZ:

129555498(SLIT1)

SSC:	100627880(SLIT1)

CFR:	102518760(SLIT1)

CBAI:

105081787(SLIT1)

CDK:	105084276(SLIT1)

VPC:	102545061(SLIT1)

BACU:

103008574(SLIT1)

BMUS:

118882737(SLIT1)

LVE:	103084137(SLIT1)

OOR:	101282064(SLIT1)

LALB:

132506720(SLIT1)

GMF:	115857837(SLIT1)

DDP:	132439755(SLIT1)

DLE:	111172439(SLIT1)

PCAD:

102983527(SLIT1)

PSIU:

116741846(SLIT1)

PPHC:

136136311(SLIT1)

NASI:

112392929(SLIT1)

ECB:	102147611(SLIT1)

EPZ:	103560833(SLIT1)

EAI:	106848531(SLIT1)

MYB:	102263801(SLIT1)

MYD:	102767832(SLIT1)

MMYO:

118669909(SLIT1)

MLF:	102425758(SLIT1)

MDT:	132214188(SLIT1)

MYUM:

139021855(SLIT1)

PKL:	118719021(SLIT1)

EFUS:

103288438(SLIT1)

MNA:	107542515(SLIT1)

DRO:	112307078(SLIT1)

SHON:

118990291(SLIT1)

AJM:	119044520(SLIT1)

PDIC:

114496364(SLIT1)

PHAS:

123828700(SLIT1)

MMF:	118632155(SLIT1)

PPAM:

129077271(SLIT1)

HAI:	109380922(SLIT1)

RFQ:	117036219(SLIT1)

PALE:

102896848(SLIT1)

PGIG:

120609255(SLIT1)

PVP:	105301403(SLIT1)

RAY:	107520412(SLIT1)

MJV:	108399906(SLIT1)

TOD:	119234205(SLIT1)

SARA:

101544196(SLIT1)

SFUM:

130029735(SLIT1)

SETR:

125994853(SLIT1)

LAV:	100670036(SLIT1)

TMU:

101351649

ETF:	101655211(SLIT1)

DNM:	101433986(SLIT1)

MDO:	100022289(SLIT1)

GAS:	123234295(SLIT1)

SHR:	100931784(SLIT1)

AFZ:

127551737

PCW:	110215484(SLIT1)

TVP:	118829557(SLIT1)

PBRV:

138145477(SLIT1)

MLAO:

141521095(SLIT1)

OAA:	100681912(SLIT1)

TACU:

119925660(SLIT1)

GGA:	395293(SLIT1)

PCOC:

116231679(SLIT1)

MGP:	100549781(SLIT1)

CJO:	107316042(SLIT1)

TPAI:

128077472(SLIT1)

LMUT:

125693057(SLIT1)

NMEL:

110400209(SLIT1)

APLA:

101799440(SLIT1)

AACU:

137859312(SLIT1)

ACYG:

106034301(SLIT1)

CATA:

118245099(SLIT1)

AFUL:

116491127(SLIT1)

TGU:	100226609(SLIT1)

LSR:	110473670(SLIT1)

SCAN:

103814151(SLIT1)

PMOA:

120502040(SLIT1)

OTC:	121341731(SLIT1)

PRUF:

121350031(SLIT1)

ATRC:

139599125(SLIT1)

GFR:	102040361(SLIT1)

FAB:	101806051(SLIT1)

OMA:	130255042(SLIT1)

PHI:	102100662(SLIT1)

PMAJ:

107206571(SLIT1)

CCAE:

111931239(SLIT1)

CCW:	104697896(SLIT1)

CBRC:

103624649(SLIT1)

ACOE:

138112555(SLIT1)

ETL:	114070670(SLIT1)

ZAB:	102064054(SLIT1)

ZLE:	135449355(SLIT1)

ACHL:

103812006(SLIT1)

SVG:	106859023(SLIT1)

MMEA:

130581947(SLIT1)

HRT:	120755785(SLIT1)

SATI:

136364473(SLIT1)

CFAI:

136293914(SLIT1)

CCIC:

134045900(SLIT1)

FPG:	101919372(SLIT1)

FCH:

102056421

CCRI:

104167668

NNT:

104410798

SHAB:

115608269(SLIT1)

ACUN:

113481673(SLIT1)

SURA:

141946226(SLIT1)

TALA:

104357782(SLIT1)

ACHC:

115348610(SLIT1)

HLE:	104830224(SLIT1)

AGEN:

126043198

HHAR:

128146985(SLIT1)

BBUT:

142030286(SLIT1)

GCL:

127017548

MNB:	103778622(SLIT1)

DPUB:

104307151(SLIT1)

PPUS:

135176012(SLIT1)

AVIT:

104277416(SLIT1)

BRHI:

104495948

EGZ:	104125644(SLIT1)

NNI:	104013613(SLIT1)

PCRI:

104024132

PARX:

142063783(SLIT1)

PADL:

103916324(SLIT1)

AFOR:

103897876(SLIT1)

FGA:

104076934

CBOR:

142084621(SLIT1)

CBOY:

140655374(SLIT1)

MAME:

142410898(SLIT1)

CLV:	102091494(SLIT1)

CNIC:

135990670(SLIT1)

MUI:	104544662(SLIT1)

PGUU:

104461171

PLET:

104622232(SLIT1)

EHS:

104508275

CMAC:

104487687

CUCA:

104059793(SLIT1)

TEO:

104384540

GAME:

129208887(SLIT1)

OHA:	104332271(SLIT1)

ACAR:

104530448

CPEA:

104390939(SLIT1)

CVF:	104288834(SLIT1)

RTD:	128911216(SLIT1)

CRID:

134517453(SLIT1)

LMIC:

141744790(SLIT1)

NARQ:

141472264(SLIT1)

AAM:	106484227(SLIT1)

AROW:

112967980(SLIT1)

NPD:

112957100

TGT:	104566647(SLIT1)

DNE:	112984783(SLIT1)

ASN:	102384547(SLIT1)

AMJ:	106739336(SLIT1)

CPOO:

109323832(SLIT1)

GGN:	109287173(SLIT1)

CIZ:	142015632(SLIT1)

CMY:	102946358(SLIT1)

CCAY:

125639669(SLIT1)

LKP:	140915107(SLIT1)

NDS:	141991232(SLIT1)

DCC:	119859188(SLIT1)

CPIC:

101932763(SLIT1)

TST:	117880805(SLIT1)

EOB:	135881775(SLIT1)

MRV:	120369032(SLIT1)

ACS:	100559877(slit1)

ASAO:

132770872(SLIT1)

PVT:	110077602(SLIT1)

SUND:

121926119(SLIT1)

PBI:	103058193(SLIT1)

PMUR:

107285592(SLIT1)

CTIG:

120302544(SLIT1)

TSR:	106552766(SLIT1)

PGUT:

117678606(SLIT1)

PCAE:

139318682(SLIT1)

APRI:

131201424(SLIT1)

PTEX:

113436609(SLIT1)

NSS:	113415619(SLIT1)

VKO:	123026790(SLIT1)

PMUA:

114597577(SLIT1)

PRAF:

128414336(SLIT1)

ZVI:	118093841(SLIT1)

HCG:	128350989(SLIT1)

GJA:	107114424(SLIT1)

STOW:

125437549(SLIT1)

EMC:	129331872(SLIT1)

XLA:	108695757 380270(slit1.S)

XTR:	100036682(slit1)

NPR:	108794657(SLIT1)

RTEM:

120909838(SLIT1)

ACAT:

141105503(SLIT1)

PADS:

140339911(SLIT1)

BBUF:

121004897(SLIT1)

BGAR:

122940252(SLIT1)

DTC:	141056175(SLIT1)

HSQ:	130283259(SLIT1)

PWL:	138300341(SLIT1)

MUO:	115470023(SLIT1)

GSH:	117359077(SLIT1)

DRE:	556123(slit1a) 561685(slit1b)

SRX:	107706111 107714155 107742809(slit1) 107753728

SANH:

107657487 107679047 107699140 107705008

SGH:	107551370 107558211 107565895 107588453

CCAR:

109045371(slit1a) 109046835 109059892(slit1b) 109101276

CAUA:

113057424 113065156 113113110

CGIB:

127943022 127970042 128026538

PTET:

122327068(slit1b) 122356428(slit1a)

LROH:

127162489(slit1b) 127174886(slit1a)

GRF:	141325564(slit1a)

OMC:	131529923(slit1b) 131551927(slit1a)

PPRM:

120468672 120468681(slit1b) 120492295(slit1a)

RKG:	130093359(slit1b) 130103831(slit1a)

MAMB:

125254444(slit1b) 125277542(slit1a)

CIDE:

127520787 127525098

CERY:

137020816(slit1a) 137029650(slit1b)

MASI:

127411723 127413734 127438441 127438751

TROS:

130549115(slit1b) 130559571(slit1a)

TDW:	130429835(slit1b) 130432048(slit1a)

MANU:

129415433(slit1a) 129453702(slit1b)

PDAB:

135731847(slit1a) 135740873(slit1b)

IPU:	108260959(slit1a)

IFU:	128604076(slit1a)

PHYP:

113544365(slit1)

SMEO:

124381521(slit1a)

TFD:	113661801(slit1a)

TVC:	132841806(slit1a)

CGAR:

128508600(slit1a)

NGRA:

132883372(slit1a)

TRN:	134325986(slit1a)

AMEX:

103038058(slit1a)

CMAO:

118816744(slit1a)

EEE:	113585397(slit1)

CHAR:

105900821(slit1a)

SPIL:

134063936(slit1a)

ASAD:

121685396(slit1a)

TRU:	101061480(slit1) 101061888

TFS:	130527389(slit1b) 130533648(slit1a)

TNG:	GSTEN00005588G001 GSTEN00010079G001

LCO:

104929884

NCC:	104955382(slit1)

TBEN:

117482037 117499877(slit1a)

CGOB:

115019808

PGEO:

117459597(slit1a)

GACU:

117538254(slit1a)

EMAC:

134858891(slit1a) 134864588(slit1b)

ELY:	117248180(slit1a) 117255211

EFO:	125885225(slit1b) 125904104(slit1a)

PLEP:

121942024 121954287(slit1a)

SLUC:

116049886 116053837(slit1a)

ECRA:

117960444(slit1a) 117961823

ESP:	116704846(slit1)

PFLV:

114564589 114571823

GAT:	120820669(slit1a)

PPUG:

119214020(slit1a) 119217858(slit1b)

AFB:	129091981(slit1a) 129095255

CLUM:

117733159(slit1b) 117743872(slit1a)

PSWI:

130189734(slit1b) 130206999(slit1a)

CANA:

137779451(slit1a) 137798720(slit1b)

CVE:	137880992(slit1a)

MSAM:

119897773(slit1b) 119917203

SCHU:

122873575(slit1b) 122883970(slit1a)

EARM:

139293833(slit1a) 139301702(slit1b)

CUD:	121508353(slit1b) 121511005(slit1a)

SPUL:

138588214(slit1a) 138594311

LMIX:

132975291(slit1a) 132983042(slit1b)

HTC:	141794853(slit1a) 141804190(slit1b)

ALAT:

119018836 119033863(slit1a)

ASTR:

137600256 137604277(slit1a)

PKLU:

139199440 139210712(slit1a)

MZE:	101467001(slit1) 101480949

ONL:	100704275 100705354

OAU:	116315599(slit1b) 116335147(slit1a)

OLA:	101161946 101164917(slit1)

OML:	112157348(slit1b) 112161605(slit1a)

CSAI:

133448792(slit1b) 133464041

XMA:	102218228 102219223(slit1)

XCO:	114137464(slit1) 114145604

XHE:	116713186(slit1) 116720221

PRET:

103470154 103476918(slit1)

PFOR:

103152224(slit1) 103154497

PLAI:

106937682 106947277(slit1)

PMEI:

106904435 106916419(slit1)

GAF:	122830053 122842396(slit1a)

PPRL:

129360181

CVG:	107081959 107086608(slit1)

CTUL:

119790765(slit1a) 119798499

GMU:	124859112(slit1a) 124867826

NFU:	107375669(slit1) 107382445

KMR:	108234074(slit1a) 108247446

ALIM:

106527139(slit1)

NWH:	119422513 119428313

AOCE:

111567186(slit1a) 111581365(slit1b)

EJA:	138195369(slit1a) 138209250

BFRE:

138615703(slit1b) 138617537

MCEP:

125001622(slit1b) 125018740(slit1a)

CSEM:

103383172 103387388(slit1)

POV:	109634541(slit1) 109643916

SSEN:

122760947 122781757(slit1a)

SSOE:

131466999 131473851(slit1a)

HHIP:

117760398 117775334(slit1a)

HSP:	118098244 118119033(slit1a)

PPLT:

128437504 128453879(slit1a)

SMAU:

118283351(slit1a) 118312348

LCF:	108880824 108888310(slit1a)

SDU:	111234356(slit1) 111235880

SLAL:

111649662 111657294

XGL:	120796240(slit1a) 120800132(slit1b)

HCQ:	109511389 109512718(slit1)

SSCV:

125968983(slit1b) 125978629(slit1a)

SBIA:

133506062 133510241(slit1a)

PEE:	133404001 133410088(slit1a)

PTAO:

133476786 133486264(slit1a)

BPEC:

110155971 110156783(slit1)

ENY:	140351683(slit1a) 140377765

MALB:

109952001 109961198(slit1)

BSPL:

114842054 114868260

SJO:	128373103(slit1a)

SSCO:

133991475(slit1a)

TTY:	137180190 137197016(slit1a)

GMH:	115540878(slit1)

SASA:

106589770 106612875(slit1)

STRU:

115153405 115177900 115177901 115200881

OTW:	112247654 112248165 112256733

OMY:	110485616 110495057 110499533 110502676(slit1a)

OGO:	124038394 124040340

ONE:

115113850

OKI:	109877215 109881416 109886283 109898903

OKE:	118361101 118374671 118383842(slit1b)

OMM:	135512160 135523480 135528314

OCLA:

139370183 139375690 139381733 139424362

SALP:

111977952 112076890

SNH:	120023487 120029397 120041317 120046726(slit1a)

SFON:

129828726 129843035 129843036 129859823

CCLU:

121533205 121547092 121574951

ELS:	105006880 105021377(slit1)

SFM:	108924720 108942586

PKI:	111848453(slit1)

AANG:

118221571(slit1b)

AROT:

135247451(slit1b)

CCOG:

133118556(slit1b)

LOC:	102686747(slit1)

PSPA:

ARUT:

PSEX:

LCM:

CPLA:

CPUN:

HOC:	132826352(slit1a)

SCAU:

119979682

LERI:

129704151(slit1a)

HAKA:

BFO:

BBEL:

SPU:

LPIC:

LVG:

OBB:

SOC:

MPHA:

AEC:

ACEP:

ACOC:

MZT:

CCOA:

PBAR:

VEM:

COBS:

TLN:

HST:

DQU:

CFO:

FEX:

PMEC:

LHU:

PGC:

OBO:

PCF:

VPS:

CGLO:

CCIN:

OVI:	T265_00606

» show all

Reference

PMID:9813312

Authors

Itoh A, Miyabayashi T, Ohno M, Sakano S

Title

Cloning and expressions of three mammalian homologues of Drosophila slit suggest possible roles for Slit in the formation and maintenance of the nervous system.

Journal

Brain Res Mol Brain Res 62:175-86 (1998)
DOI:10.1016/S0169-328X(98)00224-1

Sequence

[hsa:6585]

Reference

PMID:18363568

Authors

Hohenester E

Title

Structural insight into Slit-Robo signalling.

Journal

Biochem Soc Trans 36:251-6 (2008)
DOI:10.1042/BST0360251

LinkDB

DBGET integrated database retrieval system