KEGG   ORTHOLOGY: K00923
Entry
K00923                      KO                                     
Symbol
PIK3C2
Name
phosphatidylinositol-4-phosphate 3-kinase [EC:2.7.1.154]
Pathway
map00562  Inositol phosphate metabolism
map01100  Metabolic pathways
map04070  Phosphatidylinositol signaling system
map05132  Salmonella infection
Reaction
R03362  ATP:1-phosphatidyl-1D-myo-inositol 3-phosphotransferase
R05795  ATP:1-phosphatidyl-1D-myo-inositol-4-phosphate 3-phosphotransferase
Disease
H02595  Oculoskeletodental syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    K00923  PIK3C2; phosphatidylinositol-4-phosphate 3-kinase
 09130 Environmental Information Processing
  09132 Signal transduction
   04070 Phosphatidylinositol signaling system
    K00923  PIK3C2; phosphatidylinositol-4-phosphate 3-kinase
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    K00923  PIK3C2; phosphatidylinositol-4-phosphate 3-kinase
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.154  phosphatidylinositol-4-phosphate 3-kinase
     K00923  PIK3C2; phosphatidylinositol-4-phosphate 3-kinase
Other DBs
GO: 0035005
Genes
HSA: 5286(PIK3C2A) 5287(PIK3C2B) 5288(PIK3C2G)
PTR: 451052(PIK3C2A) 457657(PIK3C2B) 465321(PIK3C2G)
PPS: 100977462(PIK3C2A) 100982135(PIK3C2B) 100986428(PIK3C2G)
GGO: 101127796(PIK3C2A) 101132724(PIK3C2B) 101153676(PIK3C2G)
PON: 100441714(PIK3C2G) 100457125(PIK3C2A) 100461668(PIK3C2B)
NLE: 100579720(PIK3C2G) 100597241(PIK3C2B) 100597578(PIK3C2A)
HMH: 116457744(PIK3C2B) 116472743(PIK3C2G) 116476475(PIK3C2A)
MCC: 697202(PIK3C2A) 701974(PIK3C2B) 702929(PIK3C2G)
MCF: 102120715(PIK3C2G) 102130782(PIK3C2B)
MTHB: 126931691 126936311 126938071
MNI: 105481413(PIK3C2G) 105484797(PIK3C2B) 105486951(PIK3C2A)
CSAB: 103218712(PIK3C2G) 103230248(PIK3C2B) 103242212(PIK3C2A)
CATY: 105576153(PIK3C2B) 105585089(PIK3C2G) 105598902(PIK3C2A)
PANU: 100998432(PIK3C2G) 101013656(PIK3C2A) 101015413(PIK3C2B)
TGE: 112606000(PIK3C2A) 112618995(PIK3C2B) 112634471(PIK3C2G)
MLEU: 105536169(PIK3C2G) 105547054(PIK3C2B) 105548768(PIK3C2A)
RRO: 104655305(PIK3C2G) 104662349(PIK3C2A) 104667391(PIK3C2B)
RBB: 108530624(PIK3C2A) 108535188(PIK3C2B) 108539722(PIK3C2G)
TFN: 117075303(PIK3C2B) 117081669(PIK3C2A) 117090430(PIK3C2G)
PTEH: 111522778(PIK3C2B) 111552132(PIK3C2G) 111555022(PIK3C2A)
CANG: 105504385(PIK3C2B) 105508626(PIK3C2A) 105520800(PIK3C2G)
CJC: 100399595(PIK3C2A) 100401093(PIK3C2B) 100408183(PIK3C2G)
SBQ: 101034781(PIK3C2B) 101041368(PIK3C2A) 101049696(PIK3C2G)
CIMI: 108302033(PIK3C2B) 108302257(PIK3C2A) 108304622(PIK3C2G)
CSYR: 103269093(PIK3C2B) 103269762(PIK3C2A) 103275236(PIK3C2G)
MMUR: 105868409(PIK3C2B) 105879984(PIK3C2A) 105882824(PIK3C2G)
LCAT: 123626809(PIK3C2B) 123639954(PIK3C2G) 123642485(PIK3C2A)
PCOQ: 105818390(PIK3C2A) 105821220(PIK3C2B) 105825095(PIK3C2G)
OGA: 100943843(PIK3C2G) 100950927(PIK3C2B) 100965435(PIK3C2A)
MMU: 18704(Pik3c2a) 18705(Pik3c2g) 240752(Pik3c2b)
MCAL: 110296060(Pik3c2b) 110296221(Pik3c2g) 110298049(Pik3c2a)
MPAH: 110316706(Pik3c2g) 110322135(Pik3c2b) 110324799(Pik3c2a)
RNO: 116720(Pik3c2g) 289021(Pik3c2b) 361632(Pik3c2a)
MCOC: 116099223(Pik3c2b) 116099744(Pik3c2g) 116102839(Pik3c2a)
ANU: 117708613(Pik3c2a) 117715270(Pik3c2g) 117716200(Pik3c2b)
MUN: 110548259(Pik3c2b) 110554649(Pik3c2a) 110555432(Pik3c2g)
CGE: 100754324(Pik3c2g) 100756350(Pik3c2a) 100767102(Pik3c2b)
MAUA: 101825834(Pik3c2b) 101829525(Pik3c2g) 101837166(Pik3c2a)
PROB: 127212922(Pik3c2g) 127228229(Pik3c2a) 127236312(Pik3c2b)
PLEU: 114695041(Pik3c2g) 114698088(Pik3c2b) 114703707(Pik3c2a)
MORG: 121439966(Pik3c2g) 121445986(Pik3c2b) 121457504(Pik3c2a)
AAMP: 119806493(Pik3c2g) 119806938(Pik3c2a) 119827867(Pik3c2b)
NGI: 103731878(Pik3c2b) 103733924(Pik3c2g) 103750461(Pik3c2a)
HGL: 101702206(Pik3c2a) 101709126(Pik3c2g) 101721434(Pik3c2b)
CPOC: 100713375(Pik3c2g) 100719801(Pik3c2b) 100722144(Pik3c2a)
CCAN: 109690585 109695658(Pik3c2a) 109701040(Pik3c2g)
DORD: 105986508(Pik3c2b) 105992228(Pik3c2g) 105999172(Pik3c2a)
DSP: 122097749 122109379(Pik3c2b) 122117608(Pik3c2a)
PLOP: 125342733(Pik3c2g) 125359415(Pik3c2b) 125361661(Pik3c2a)
MMMA: 107135675(Pik3c2a) 107140714(Pik3c2b) 107152704(Pik3c2g)
OPI: 101519066(PIK3C2A) 101521983(PIK3C2G) 101531063(PIK3C2B)
TUP: 102479782(PIK3C2B) 102482382(PIK3C2G) 102494296(PIK3C2A)
GVR: 103590941(PIK3C2A) 103594173(PIK3C2B) 103598708 103605556
CFA: 477681(PIK3C2G) 478938(PIK3C2B) 485399(PIK3C2A)
CLUD: 112643241(PIK3C2B) 112665455(PIK3C2G) 112667693(PIK3C2A)
VVP: 112914394(PIK3C2B) 112917545(PIK3C2G) 112927036(PIK3C2A)
VLG: 121476233(PIK3C2A) 121479696(PIK3C2G) 121501727(PIK3C2B)
NPO: 129505140(PIK3C2A) 129505658(PIK3C2G) 129515295(PIK3C2B)
AML: 100465834(PIK3C2B) 100470614(PIK3C2G) 100481616(PIK3C2A)
UMR: 103671007(PIK3C2B) 103677799(PIK3C2G) 103679391(PIK3C2A)
UAH: 113242503(PIK3C2B) 113246608(PIK3C2A) 113257834(PIK3C2G)
UAR: 123781709(PIK3C2G) 123785698(PIK3C2B) 123791675(PIK3C2A)
MPUF: 101669918(PIK3C2G) 101672435(PIK3C2B) 101678954(PIK3C2A)
MNP: 132020294(PIK3C2G) 132022431(PIK3C2A) 132025645(PIK3C2B)
MLK: 131809904(PIK3C2A) 131814288(PIK3C2B) 131838988(PIK3C2G)
NVS: 122891516(PIK3C2G) 122912753(PIK3C2A) 122918824(PIK3C2B)
ORO: 101373040(PIK3C2A) 101374529(PIK3C2G) 101381985(PIK3C2B)
EJU: 114219345(PIK3C2A) 114221707(PIK3C2G) 114221915(PIK3C2B)
ZCA: 113915414(PIK3C2A) 113922084(PIK3C2G) 113932133(PIK3C2B)
MLX: 118004232(PIK3C2A) 118014159(PIK3C2B) 118025609(PIK3C2G)
NSU: 110576245(PIK3C2A) 110577319(PIK3C2B) 110580725(PIK3C2G)
LWW: 102734244(PIK3C2B) 102737251(PIK3C2G) 102749488(PIK3C2A)
FCA: 101082204(PIK3C2B) 101084293(PIK3C2G) 101096512(PIK3C2A)
PYU: 121021677(PIK3C2B) 121038861(PIK3C2G) 121043709(PIK3C2A)
PCOO: 112857726(PIK3C2B) 112864920(PIK3C2A) 112867236(PIK3C2G)
PBG: 122472196(PIK3C2G) 122476297(PIK3C2B) 122484396(PIK3C2A)
PVIV: 125155292(PIK3C2B) 125171119(PIK3C2G) 125176163(PIK3C2A)
PTG: 102966367(PIK3C2B) 102967722(PIK3C2G) 102970607(PIK3C2A)
PPAD: 109250467(PIK3C2B) 109268679(PIK3C2G) 109271194(PIK3C2A)
HHV: 120224016(PIK3C2G) 120228887(PIK3C2B) 120234768(PIK3C2A)
BTA: 513301(PIK3C2G) 537396(PIK3C2B) 537790(PIK3C2A)
BOM: 102268893(PIK3C2B) 102274862(PIK3C2A) 102275146(PIK3C2G)
BIU: 109559610(PIK3C2G) 109568816(PIK3C2A) 109570348(PIK3C2B)
BBUB: 102390969(PIK3C2A) 102411841(PIK3C2G) 102415576(PIK3C2B)
BBIS: 104981436(PIK3C2A) 104998868(PIK3C2B) 105002211(PIK3C2G)
CHX: 102172975(PIK3C2G) 102180522(PIK3C2B) 102186784(PIK3C2A)
OAS: 101108766(PIK3C2B) 101114899(PIK3C2A) 101123108(PIK3C2G)
BTAX: 128048299(PIK3C2G) 128060229(PIK3C2A) 128061331(PIK3C2B)
ODA: 120858909(PIK3C2G) 120876400(PIK3C2A) 120879969(PIK3C2B)
CCAD: 122423954(PIK3C2G) 122449449(PIK3C2A) 122451784(PIK3C2B)
MBEZ: 129535709(PIK3C2G) 129551771(PIK3C2B) 129554473(PIK3C2A)
SSC: 100512551(PIK3C2B) 100514626(PIK3C2A) 100523844(PIK3C2G)
CFR: 102505793(PIK3C2B) 102511853(PIK3C2G) 102524329(PIK3C2A)
CBAI: 105062269(PIK3C2G) 105076596(PIK3C2A) 105076861(PIK3C2B)
CDK: 105086672(PIK3C2A) 105096498 105098645(PIK3C2B)
VPC: 102526233(PIK3C2B) 102535923(PIK3C2A) 102543602(PIK3C2G)
BACU: 103001723(PIK3C2A) 103003092(PIK3C2G) 103013842(PIK3C2B)
BMUS: 118897322(PIK3C2B) 118899146(PIK3C2A) 118902462(PIK3C2G)
LVE: 103070172(PIK3C2B) 103073583(PIK3C2G) 103075790(PIK3C2A)
OOR: 101270509(PIK3C2A) 101270703(PIK3C2G) 101282610(PIK3C2B)
DLE: 111165294(PIK3C2A) 111176819(PIK3C2G) 111184786(PIK3C2B)
PCAD: 102986532(PIK3C2G) 102988401(PIK3C2A) 102996301(PIK3C2B)
PSIU: 116757420(PIK3C2B) 116758613(PIK3C2A) 116761360(PIK3C2G)
NASI: 112390590(PIK3C2A) 112391778(PIK3C2G) 112403472(PIK3C2B)
ECB: 100054391(PIK3C2B) 100056431(PIK3C2A) 100064130(PIK3C2G)
EAI: 106823801(PIK3C2B) 106823849(PIK3C2G) 106835478(PIK3C2A)
MYB: 102239081(PIK3C2G) 102240421(PIK3C2B) 102241008(PIK3C2A)
MYD: 102753072(PIK3C2G) 102757168(PIK3C2B) 102764227(PIK3C2A)
MMYO: 118651878(PIK3C2G) 118664875(PIK3C2A) 118673035(PIK3C2B)
MLF: 102417879(PIK3C2G) 102418474(PIK3C2B) 102421390(PIK3C2A)
PKL: 118712519(PIK3C2A) 118721467(PIK3C2B) 118730251(PIK3C2G)
EFUS: 103285131(PIK3C2G) 103294595(PIK3C2A) 103297504(PIK3C2B)
MNA: 107525348(PIK3C2G) 107539064(PIK3C2B) 107546701(PIK3C2A)
DRO: 112303229(PIK3C2A) 112317971(PIK3C2B) 112318462(PIK3C2G)
SHON: 118978363(PIK3C2G) 118989717(PIK3C2A) 119001722(PIK3C2B)
AJM: 119042851(PIK3C2G) 119053072(PIK3C2A) 119056788(PIK3C2B)
PDIC: 114500961(PIK3C2A) 114511823(PIK3C2B) 114514164(PIK3C2G)
PHAS: 123809968(PIK3C2A) 123813070(PIK3C2G) 123820594(PIK3C2B)
MMF: 118623596(PIK3C2G) 118629036(PIK3C2A) 118637280(PIK3C2B)
PPAM: 129062335(PIK3C2B) 129080532(PIK3C2A) 129084992(PIK3C2G)
HAI: 109371228(PIK3C2G) 109386461(PIK3C2B) 109388111(PIK3C2A)
RFQ: 117014760(PIK3C2B) 117028031(PIK3C2G) 117030246(PIK3C2A)
PALE: 102885293(PIK3C2A) 102886908(PIK3C2G) 102897381(PIK3C2B)
PGIG: 120593614(PIK3C2A) 120617971(PIK3C2B) 120618393(PIK3C2G)
PVP: 105300629(PIK3C2G) 105300678(PIK3C2B) 105304234(PIK3C2A)
RAY: 107499672(PIK3C2G) 107508035(PIK3C2A) 107508392(PIK3C2B)
MJV: 108384332(PIK3C2G) 108393904(PIK3C2A) 108408664(PIK3C2B)
TOD: 119234936(PIK3C2B) 119247664(PIK3C2G) 119255504(PIK3C2A)
SARA: 101538997(PIK3C2G) 101551037(PIK3C2B) 101552113(PIK3C2A)
SETR: 126004164(PIK3C2B) 126018885(PIK3C2A) 126022029(PIK3C2G)
LAV: 100655072(PIK3C2B) 100655519(PIK3C2G) 100660293(PIK3C2A)
ETF: 101643787(PIK3C2B) 101644831(PIK3C2G) 101662368(PIK3C2A)
DNM: 101432529(PIK3C2G) 101433266(PIK3C2A) 101435301(PIK3C2B)
MDO: 100017523(PIK3C2B) 100028742(PIK3C2A)
GAS: 123247002(PIK3C2B) 123252882(PIK3C2A)
SHR: 100913785(PIK3C2B) 100930379(PIK3C2A)
PCW: 110219604(PIK3C2B) 110220993(PIK3C2A)
OAA: 100075377(PIK3C2B) 100079037(PIK3C2A)
GGA: 418181(PIK3C2G) 419822(PIK3C2B) 423070(PIK3C2A)
PCOC: 116231833(PIK3C2G) 116237059(PIK3C2B) 116242869(PIK3C2A)
CJO: 107314653(PIK3C2A) 107316443(PIK3C2G) 107324700(PIK3C2B)
TPAI: 128073559(PIK3C2G) 128086300(PIK3C2A) 128087977(PIK3C2B)
LMUT: 125684198(PIK3C2B) 125694485(PIK3C2A) 125697629(PIK3C2G)
NMEL: 110388177(PIK3C2B) 110395887(PIK3C2G) 110401611(PIK3C2A)
APLA: 101790027(PIK3C2G) 101797372(PIK3C2B) 101805189(PIK3C2A)
ACYG: 106030889(PIK3C2G) 106033935(PIK3C2A) 106041283(PIK3C2B)
CATA: 118249793(PIK3C2A) 118250115(PIK3C2G) 118255315(PIK3C2B)
AFUL: 116489576(PIK3C2A) 116498702(PIK3C2B) 116502339(PIK3C2G)
TGU: 100219236(PIK3C2G) 100219982(PIK3C2A) 100228453(PIK3C2B)
LSR: 110468056(PIK3C2A) 110472981(PIK3C2G) 110475005(PIK3C2B)
SCAN: 103820487(PIK3C2G) 103826780(PIK3C2A) 108963600(PIK3C2B)
PMOA: 120499085(PIK3C2B) 120501177(PIK3C2A) 120501717(PIK3C2G)
OTC: 121332848(PIK3C2G) 121341469(PIK3C2A) 121345560(PIK3C2B)
PRUF: 121355231(PIK3C2B) 121360985(PIK3C2A) 121362708(PIK3C2G)
GFR: 102031753(PIK3C2B) 102034587(PIK3C2A) 102037952(PIK3C2G)
FAB: 101810900(PIK3C2B) 101811315(PIK3C2G) 101813229(PIK3C2A)
OMA: 130254335(PIK3C2A) 130263803(PIK3C2G)
PHI: 102100989(PIK3C2B) 102104821(PIK3C2A) 102108230(PIK3C2G)
PMAJ: 107205187(PIK3C2G) 107205946(PIK3C2A) 107214772(PIK3C2B)
CCAE: 111928278(PIK3C2G) 111930817(PIK3C2A) 111939688(PIK3C2B)
CCW: 104684201(PIK3C2A) 104692271(PIK3C2G) 104692486(PIK3C2B)
CBRC: 103624735 103624909(PIK3C2A) 103625388(PIK3C2B)
ETL: 114062470(PIK3C2A) 114067902 114069121(PIK3C2B)
ZAB: 102065402(PIK3C2A) 102066882 102075337(PIK3C2G)
ZLE: 135448755(PIK3C2A) 135458043(PIK3C2B) 135459269(PIK3C2G)
ACHL: 103807424(PIK3C2G) 103809336(PIK3C2A)
SVG: 106849361(PIK3C2G) 106850913(PIK3C2B) 106853208(PIK3C2A)
MMEA: 130575411(PIK3C2A) 130582852(PIK3C2G)
HRT: 120752240(PIK3C2G) 120753604(PIK3C2A) 120762847(PIK3C2B)
FPG: 101914006(PIK3C2A) 101915094(PIK3C2B)
FCH: 102046914(PIK3C2B) 102058269(PIK3C2A) 102059409(PIK3C2G)
CLV: 102093585(PIK3C2B) 102096662(PIK3C2A)
EGZ: 104123200(PIK3C2A) 104125797(PIK3C2B) 104135084(PIK3C2G)
NNI: 104010656(PIK3C2A) 104013205(PIK3C2B) 104017951(PIK3C2G)
PCRI: 104034788(PIK3C2A)
PLET: 104619861(PIK3C2A) 104621883(PIK3C2G)
EHS: 104505679(PIK3C2A) 104507871(PIK3C2G)
PCAO: 104044468(PIK3C2A) 104046205(PIK3C2G)
ACUN: 113481213(PIK3C2A) 113488343(PIK3C2G) 113488786(PIK3C2B)
TALA: 104357153(PIK3C2A) 104364002(PIK3C2G) 116965595(PIK3C2B)
PADL: 103919855(PIK3C2B) 103920719(PIK3C2A) 103924344(PIK3C2G)
AFOR: 103893695(PIK3C2B) 103898672(PIK3C2G) 103906743(PIK3C2A)
ACHC: 115335244(PIK3C2B) 115351797(PIK3C2A) 115352825(PIK3C2G)
HALD: 104313947(PIK3C2A) 104321921(PIK3C2G)
HLE: 104829531(PIK3C2A) 104831018(PIK3C2G) 104839589(PIK3C2B)
CCRI: 104169600(PIK3C2A)
CSTI: 104560139(PIK3C2A)
CMAC: 104485363(PIK3C2A)
MUI: 104547266(PIK3C2A)
BREG: 104631875(PIK3C2A)
FGA: 104081189(PIK3C2A)
GSTE: 104255970(PIK3C2G) 104261503(PIK3C2A)
LDI: 104339958(PIK3C2A) 104351852(PIK3C2G)
MNB: 103770637(PIK3C2A) 103772360(PIK3C2G)
OHA: 104330100(PIK3C2A) 104333025 104337113(PIK3C2G)
NNT: 104412269(PIK3C2A)
SHAB: 115602285(PIK3C2B) 115605664(PIK3C2G) 115606321(PIK3C2A)
DPUB: 104302307(PIK3C2G) 104304401(PIK3C2A) 104305409(PIK3C2B)
PGUU: 104461246(PIK3C2A) 104468545(PIK3C2G)
ACAR: 104518554
CPEA: 104386748(PIK3C2A) 104393445(PIK3C2G) 104398250(PIK3C2B)
AVIT: 104275092(PIK3C2A)
CVF: 104281626(PIK3C2G) 104289354(PIK3C2B) 104292611(PIK3C2A)
RTD: 128900358(PIK3C2B) 128908272(PIK3C2A) 128919636(PIK3C2G)
CUCA: 104060278(PIK3C2B) 104065641(PIK3C2G) 104068882(PIK3C2A)
TEO: 104376489(PIK3C2A)
BRHI: 104498699(PIK3C2A)
AAM: 106488942(PIK3C2G) 106497098(PIK3C2A)
AROW: 112966611(PIK3C2G) 112971594(PIK3C2B) 112972435(PIK3C2A)
NPD: 112944184(PIK3C2G) 112948830(PIK3C2A) 112959125(PIK3C2B)
TGT: 104579970(PIK3C2G) 104580443(PIK3C2A)
DNE: 112985666(PIK3C2A) 112987784(PIK3C2G) 112990281(PIK3C2B)
SCAM: 104140411 104142145(PIK3C2G)
ASN: 102380020(PIK3C2B) 102382160(PIK3C2G) 102387688(PIK3C2A)
AMJ: 102564420(PIK3C2B) 102573536(PIK3C2A) 102577227(PIK3C2G)
CPOO: 109315917(PIK3C2G) 109317749(PIK3C2B) 109321191(PIK3C2A)
GGN: 109295227(PIK3C2B) 109296426(PIK3C2G) 109299124(PIK3C2A)
PSS: 102449395(PIK3C2B) 102453034(PIK3C2A) 102462105
CMY: 102936736(PIK3C2B) 102936873(PIK3C2A) 102941758(PIK3C2G)
CCAY: 125624949(PIK3C2B) 125625463(PIK3C2G)
DCC: 119846391(PIK3C2B) 119856685(PIK3C2A) 119863339(PIK3C2G)
CPIC: 101931624(PIK3C2G) 101944776(PIK3C2B) 101951383(PIK3C2A)
TST: 117875800(PIK3C2B) 117877244(PIK3C2A) 117883063(PIK3C2G)
CABI: 116827909(PIK3C2B) 116834139(PIK3C2G) 116835939(PIK3C2A)
MRV: 120402992(PIK3C2A) 120403823(PIK3C2B) 120408032(PIK3C2G)
ACS: 100557407(pik3c2a) 100567393(pik3c2b)
ASAO: 132770645(PIK3C2A) 132773641(PIK3C2B)
PVT: 110079700(PIK3C2B) 110083988(PIK3C2A)
SUND: 121927575 121929224(PIK3C2B)
PBI: 103049748(PIK3C2A) 103055047(PIK3C2B)
PMUR: 107298464 107302983(PIK3C2B)
CTIG: 120306882(PIK3C2B) 120308492(PIK3C2A)
TSR: 106552466 106557105(PIK3C2B)
PGUT: 117663906 117665275(PIK3C2A) 132708875(PIK3C2B)
APRI: 131185809(PIK3C2A)
PTEX: 113440247(PIK3C2A) 113446096(PIK3C2B)
NSS: 113412577(PIK3C2A) 113418128(PIK3C2B)
VKO: 123021237(PIK3C2A) 123031113(PIK3C2B)
PMUA: 114598648(PIK3C2A) 114599287(PIK3C2B)
PRAF: 128415877(PIK3C2A) 128416092(PIK3C2B)
ZVI: 118087490(PIK3C2A) 118088148(PIK3C2B)
HCG: 128323919(PIK3C2B) 128345395(PIK3C2A)
GJA: 107119701(PIK3C2B) 107120532(PIK3C2A)
STOW: 125425984(PIK3C2A) 125432703(PIK3C2B)
EMC: 129323828(PIK3C2A) 129329717(PIK3C2B)
XLA: 100380949(pik3c2a.L) 108708909 108712508 108715313(pik3c2a.S)
XTR: 100038240(pik3c2a) 100496878(pik3c2g)
NPR: 108791810(PIK3C2G) 108796352(PIK3C2B) 108800795(PIK3C2A)
RTEM: 120921978(PIK3C2A) 120928434(PIK3C2B) 120932788(PIK3C2G)
BBUF: 120981046(PIK3C2A) 120995038(PIK3C2B) 121003440(PIK3C2G)
BGAR: 122920153(PIK3C2A) 122926116(PIK3C2G) 122933426(PIK3C2B)
MUO: 115468914(PIK3C2A) 115478018(PIK3C2G) 115481699(PIK3C2B)
GSH: 117347296(PIK3C2B) 117352191(PIK3C2A) 117363875(PIK3C2G)
DRE: 100330514(pik3c2g) 567938(pik3c2b) 571356(pik3c2a)
SANH: 107660757(pik3c2b) 107690350 107690894(pik3c2g) 107691134
PTET: 122335723(pik3c2g) 122354061(pik3c2b) 122362834(pik3c2a)
LROH: 127173073(pik3c2b) 127180757(pik3c2a) 127181223(pik3c2g)
OMC: 131524177(pik3c2g) 131524214(pik3c2a) 131549317(pik3c2b)
PPRM: 120459950(pik3c2g) 120487656(pik3c2a) 120495261(pik3c2b)
RKG: 130088945(pik3c2a) 130103587(pik3c2b) 130106022(pik3c2g)
MAMB: 125253803(pik3c2a) 125254006(pik3c2g) 125256873(pik3c2b)
TROS: 130562650(pik3c2a) 130571143(pik3c2b)
TDW: 130410157(pik3c2b) 130435377(pik3c2a)
MANU: 129418588(pik3c2a) 129427404(pik3c2b)
IFU: 128606819(pik3c2a) 128624825(pik3c2b)
PHYP: 113526545(pik3c2a) 113539558(pik3c2b)
SMEO: 124395591(pik3c2a) 124402108(pik3c2b)
TFD: 113641530(pik3c2b) 113660927(pik3c2a)
TVC: 132838065(pik3c2b) 132851077(pik3c2a)
TRN: 134301511(pik3c2b) 134323696(pik3c2a)
AMEX: 103042558(pik3c2a) 103046979(pik3c2b)
CMAO: 118799983(pik3c2b) 118801364(pik3c2a)
EEE: 113576605(pik3c2a) 113576623(pik3c2g) 113589083(pik3c2b)
CHAR: 105895879(pik3c2b) 105905592(pik3c2a) 105910366(pik3c2g)
TRU: 101065977(pik3c2a) 101074574(pik3c2g) 105419181(pik3c2b)
TFS: 130523955 130536245(pik3c2a) 130536850(pik3c2g)
LCO: 104921784(pik3c2a) 104937642(pik3c2b) 104940676(pik3c2g)
NCC: 104942429(pik3c2g)
TBEN: 117471970 117494965(pik3c2g) 117497327(pik3c2a)
CGOB: 115009630(pik3c2a) 115009803
PGEO: 117447515(pik3c2a) 117448604(pik3c2g)
GACU: 117538957(pik3c2g) 117557463(pik3c2a)
EMAC: 134882489(pik3c2a) 134882892(pik3c2g) 134882929(pik3c2b)
ELY: 117256637(pik3c2b) 117262184(pik3c2a) 117262419(pik3c2g)
EFO: 125886895(pik3c2a) 125887175(pik3c2g) 125904698(pik3c2b)
PLEP: 121949830(pik3c2a) 121950288(pik3c2g)
SLUC: 116038419(pik3c2g) 116046816(pik3c2a) 116061840(pik3c2b)
ECRA: 117949249(pik3c2a) 117949793(pik3c2g)
ESP: 116693588(pik3c2a) 116694205(pik3c2g)
PFLV: 114554406 114559771(pik3c2a) 114559988(pik3c2g)
GAT: 120809527(pik3c2a) 120809646(pik3c2g) 120834874(pik3c2b)
PPUG: 119195503(pik3c2a) 119196721(pik3c2g) 119229781(pik3c2b)
AFB: 129105174(pik3c2b) 129108237(pik3c2g) 129108445(pik3c2a)
CLUM: 117730401(pik3c2b) 117731766(pik3c2g) 117731808(pik3c2a)
PSWI: 130194940(pik3c2a) 130195365(pik3c2g) 130207890(pik3c2b)
MSAM: 119885962(pik3c2b) 119893087(pik3c2a) 119894203(pik3c2g)
SCHU: 122874591(pik3c2a) 122874633(pik3c2g) 122886139(pik3c2b)
CUD: 121506704(pik3c2b) 121514810(pik3c2a) 121514893(pik3c2g)
ALAT: 119021107(pik3c2b) 119023956(pik3c2a) 119024464(pik3c2g)
MZE: 101464810(pik3c2b) 101481785(pik3c2a) 101488075(pik3c2g) 112434824
ONL: 100697097(pik3c2a) 100701633(pik3c2g) 100704299
OAU: 116313962(pik3c2a) 116322116(pik3c2b) 116332676(pik3c2g)
OLA: 101155105(pik3c2a) 101162831(pik3c2b) 105354205(pik3c2g)
OML: 112144879(pik3c2b) 112151962(pik3c2a) 112152117(pik3c2g)
CSAI: 133443684(pik3c2a) 133443764(pik3c2g) 133449011(pik3c2b)
XMA: 102218236(pik3c2b) 102221445(pik3c2g) 102225822(pik3c2a)
XCO: 114135879(pik3c2b) 114157212(pik3c2a) 114159765(pik3c2g)
PRET: 103464245(pik3c2b) 103465708(pik3c2a) 103466393(pik3c2g)
PFOR: 103129727(pik3c2b) 103150267(pik3c2g) 103156569(pik3c2a)
PLAI: 106936945(pik3c2b) 106962227 106964266(pik3c2a)
PMEI: 106908472(pik3c2b) 106926826(pik3c2g) 106931303(pik3c2a)
GAF: 122834523(pik3c2b) 122835590(pik3c2a) 122836211(pik3c2g)
PPRL: 129355130 129356271 129359658(pik3c2a) 129360683(pik3c2g)
CVG: 107090881(pik3c2a) 107092729(pik3c2g) 107102075(pik3c2b)
CTUL: 119783244(pik3c2g) 119789737(pik3c2a) 119794293(pik3c2b)
GMU: 124856832(pik3c2b) 124879241(pik3c2a) 124883794(pik3c2g)
NFU: 107384865(pik3c2b) 107388363(pik3c2a) 107388607(pik3c2g)
KMR: 108229826(pik3c2g) 108245738(pik3c2a) 108251758(pik3c2b)
ALIM: 106522805(pik3c2a) 106523395(pik3c2g) 106525737(pik3c2b)
NWH: 119412685(pik3c2b) 119415812(pik3c2g) 119415924(pik3c2a)
AOCE: 111573650(pik3c2g) 111580508(pik3c2a) 111580517(pik3c2b)
MCEP: 125006361(pik3c2b) 125014973(pik3c2a) 125015398(pik3c2g)
CSEM: 103379820(pik3c2a) 103380432(pik3c2g) 103386838(pik3c2b)
POV: 109623667 109624395(pik3c2a)
SSEN: 122768671(pik3c2b) 122776457(pik3c2a) 122776471(pik3c2g)
HHIP: 117762141(pik3c2b) 117763535(pik3c2g) 117763645(pik3c2a)
HSP: 118104829(pik3c2b) 118109288(pik3c2a) 118110261(pik3c2g)
PPLT: 128444322(pik3c2a) 128444937(pik3c2g) 128450164(pik3c2b)
SMAU: 118309708(pik3c2b) 118314823(pik3c2a) 118315381(pik3c2g)
SDU: 111219371(pik3c2b) 111229571(pik3c2a) 111229760(pik3c2g)
SLAL: 111650372(pik3c2a) 111656524(pik3c2b) 111661662(pik3c2g)
XGL: 120792700(pik3c2g) 120793021(pik3c2a) 120807452(pik3c2b)
HCQ: 109507628 109522463(pik3c2b) 109530836(pik3c2a)
SBIA: 133501943(pik3c2a) 133502467(pik3c2g) 133507375(pik3c2b)
PEE: 133402466(pik3c2g) 133403363(pik3c2a) 133409156(pik3c2b)
PTAO: 133478250(pik3c2a) 133478611(pik3c2g) 133483155(pik3c2b)
BPEC: 110160352(pik3c2a) 110169655 110174613(pik3c2b)
MALB: 109956435(pik3c2a) 109966904(pik3c2b) 109973002(pik3c2g)
BSPL: 114856196(pik3c2b) 114857220(pik3c2a) 114857343(pik3c2g)
SJO: 128355429(pik3c2b) 128358689(pik3c2a) 128359374(pik3c2g)
ELS: 105016798(pik3c2b) 105018471(pik3c2a) 105028898(pik3c2g)
SFM: 108931427(pik3c2g) 108938229(pik3c2b) 108939855(pik3c2a)
PKI: 111838684(pik3c2b) 111842563(pik3c2a) 111851209
AANG: 118211495(pik3c2b) 118215214 118227175(pik3c2a) 118231141(pik3c2g)
LOC: 102687883(pik3c2b) 102689643(pik3c2a)
PSEX: 120518134(pik3c2a) 120526168(pik3c2b)
LCM: 102346693(PIK3C2A) 102347853(PIK3C2G) 102365794(PIK3C2B)
CMK: 103174900(pik3c2a) 103182539(pik3c2b)
RTP: 125485812
CPLA: 122557774(pik3c2a) 122561603 122563070(pik3c2b)
HOC: 132824444(pik3c2a) 132828325(pik3c2b)
LERI: 129705938(pik3c2a) 129707687 129708865(pik3c2b)
BFO: 118414477
BBEL: 109481794
CIN: 100175620
SCLV: 120333773
SPU: 586734
LPIC: 129267985
APLC: 110975484
SKO: 100371292
DME: Dmel_CG11621(Pi3K68D)
DSE: 6605334
DSI: Dsimw501_GD12776(Dsim_GD12776)
DAN: 6507145
DSR: 110179005
DPO: 4811995
DPE: 6600653
DMN: 108152220
DGR: 6558387
DAZ: 108614224
DNV: 108652118
DHE: 111598385
DVI: 6623593
CCAT: 101452404
BOD: 106618273
BDR: 105224763
RZE: 108374523
AOQ: 129242326
TDA: 119668650
MDE: 101896512
SCAC: 106095665
LCQ: 111684075
LSQ: 119605619
GFS: 119632713
ECOE: 129942345
CLON: 129610130
HIS: 119647657
AGA: 4577553
ACOZ: 120957408
AARA: 120904155
AMER: 121600347
ASTE: 118503788
AFUN: 125767311
AMOU: 128307580
AALI: 118466386
AAG: 5576326
AALB: 109407641
ASUA: 134227339
CPII: 120427872
CNS: 116350892
BCOO: 119084597
AME: 413425
ACER: 107994957
ALAB: 122715258
ADR: 102671522
AFLR: 100871174
BIM: 100748686
BBIF: 117207554
BVK: 117232983
BVAN: 117156761
BTER: 100649222
BAFF: 126917586
BPYO: 122572265
BPAS: 132907028
FVI: 122528811
CCAL: 108629757
OBB: 114872695
OLG: 117607681
MGEN: 117228131
NMEA: 116425435
CGIG: 122400293
SOC: 105199002
MPHA: 105829544
AEC: 105147824
ACEP: 105625481
PBAR: 105422981
VEM: 105561766
HST: 105187092
DQU: 106750598
CFO: 105250545
LHU: 105678054
PGC: 109853821
OBO: 105283495
PCF: 106789070
PFUC: 122524077
VPS: 122627454
VCRB: 124422710
VVE: 124947634
NVI: 100121969
CSOL: 105360131
TPRE: 106659349
LHT: 122504859
LBD: 127281101
MDL: 103569923
CGLO: 123272093
FAS: 105263127
DAM: 107038390
AGIF: 122851306
CINS: 118065698
VCAN: 122405965
CCIN: 107269969
DSM: 124412313
NPT: 124221340
NFB: 124184294
NLO: 107217970
NVG: 124306682
AROA: 105688065
TCA: 655501
DPA: 109533351
SOY: 115876959
AGRG: 126735936
ATD: 109594760
CSET: 123318763
AGB: 108906883
LDC: 111509548
DVV: 114325900
NVL: 108563833
APLN: 108738367
PPYR: 116164460
OTU: 111414330
BMOR: 101742216
BMAN: 114241766
MSEX: 115442166
BANY: 112053616
MJU: 123866409
NIQ: 126781817
VCD: 124544196
MCIX: 123670262
PXU: 106113452
PRAP: 110994508
PBX: 123711500
PNAP: 125059118
ZCE: 119833477
CCRC: 123691589
LSIN: 126976951
AAGE: 121728976
HAW: 110378347
HZE: 124632742
TNL: 113507614
SLIU: 111358209
OFU: 114355309
ATRA: 106139235
PXY: 105394948
PGW: 126366186
LGLY: 125228499
CFEL: 113369759
CCRN: 123292471
API: 100160780
DNX: 107166792
AGS: 114124237
RMD: 113552736
ACOO: 126846219
DVT: 126900893
BTAB: 109042143
DCI: 103520162
CLEC: 106666598
HHAL: 106686525
NLU: 111061019
HVI: 124358058
FOC: 113206440
TPAL: 117650465
ZNE: 110830244
CSEC: 111863236
SGRE: 126282227
BROR: 134539557
IEL: 124162640
FCD: 110850824
DMK: 116925062
DPZ: 124344258
PVM: 113819838
PJA: 122242193
PCHN: 125043513
PMOO: 119585670
HAME: 121872594
PCLA: 123755348
PTRU: 123504774
ESN: 126996601
MNZ: 135214478
HAZT: 108674302
EAF: 111718347
LSM: 121114934
TCF: 131877974
PPOI: 119091755
VDE: 111250268
VJA: 111272736
TUT: 107360527
DPTE: 113793502
DFR: 124492112
CSCU: 111619612
PTEP: 107437171
ABRU: 129983860
UDV: 129224285
SDM: 118186232
PMEO: 129586257
CEL: CELE_F39B1.1(piki-1)
CBR: CBG_07670(Cbr-piki-1)
BMY: BM_BM3926(Bma-piki-1)
PCAN: 112559398
BGT: 106069895
GAE: 121382287
HRF: 124120727
HRJ: 124268743
CRG: 105340044
CVN: 111126338
CANU: 128172764
OED: 125682956
MYI: 110441528
PMAX: 117336482
MMER: 123536860
RPHI: 132723114
DPOL: 127847468
OBI: 106869736
OSN: 115213843
LJP: 135466276
LAK: 106172136
EGL: EGR_05933
LLON: 135492037
NVE: 5517990
EPA: 110233446
ATEN: 116286727
ADF: 107335827
AMIL: 114955439
PDAM: 113682593
SPIS: 111322228
DGT: 114516438
XEN: 124437391
HMG: 100211167
HSY: 130613988
AQU: 100639364
DDI: DDB_G0291093(pikH)
DFA: DFA_03210(pikH)
 » show all
Reference
PMID:9337861
  Authors
Domin J, Pages F, Volinia S, Rittenhouse SE, Zvelebil MJ, Stein RC, Waterfield MD
  Title
Cloning of a human phosphoinositide 3-kinase with a C2 domain that displays reduced sensitivity to the inhibitor wortmannin.
  Journal
Biochem J 326 ( Pt 1):139-47 (1997)
DOI:10.1042/bj3260139
  Sequence
[hsa:5286]
LinkDB

KEGG   ORTHOLOGY: K02649
Entry
K02649                      KO                                     
Symbol
PIK3R1_2_3
Name
phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
Pathway
map01521  EGFR tyrosine kinase inhibitor resistance
map01522  Endocrine resistance
map01524  Platinum drug resistance
map04012  ErbB signaling pathway
map04014  Ras signaling pathway
map04015  Rap1 signaling pathway
map04024  cAMP signaling pathway
map04062  Chemokine signaling pathway
map04066  HIF-1 signaling pathway
map04068  FoxO signaling pathway
map04070  Phosphatidylinositol signaling system
map04071  Sphingolipid signaling pathway
map04072  Phospholipase D signaling pathway
map04140  Autophagy - animal
map04150  mTOR signaling pathway
map04151  PI3K-Akt signaling pathway
map04152  AMPK signaling pathway
map04210  Apoptosis
map04211  Longevity regulating pathway
map04213  Longevity regulating pathway - multiple species
map04218  Cellular senescence
map04360  Axon guidance
map04370  VEGF signaling pathway
map04380  Osteoclast differentiation
map04510  Focal adhesion
map04550  Signaling pathways regulating pluripotency of stem cells
map04611  Platelet activation
map04613  Neutrophil extracellular trap formation
map04620  Toll-like receptor signaling pathway
map04625  C-type lectin receptor signaling pathway
map04630  JAK-STAT signaling pathway
map04650  Natural killer cell mediated cytotoxicity
map04660  T cell receptor signaling pathway
map04662  B cell receptor signaling pathway
map04664  Fc epsilon RI signaling pathway
map04666  Fc gamma R-mediated phagocytosis
map04668  TNF signaling pathway
map04670  Leukocyte transendothelial migration
map04722  Neurotrophin signaling pathway
map04725  Cholinergic synapse
map04750  Inflammatory mediator regulation of TRP channels
map04810  Regulation of actin cytoskeleton
map04910  Insulin signaling pathway
map04914  Progesterone-mediated oocyte maturation
map04915  Estrogen signaling pathway
map04917  Prolactin signaling pathway
map04919  Thyroid hormone signaling pathway
map04923  Regulation of lipolysis in adipocytes
map04926  Relaxin signaling pathway
map04929  GnRH secretion
map04930  Type II diabetes mellitus
map04931  Insulin resistance
map04932  Non-alcoholic fatty liver disease
map04933  AGE-RAGE signaling pathway in diabetic complications
map04935  Growth hormone synthesis, secretion and action
map04960  Aldosterone-regulated sodium reabsorption
map04973  Carbohydrate digestion and absorption
map05010  Alzheimer disease
map05017  Spinocerebellar ataxia
map05020  Prion disease
map05100  Bacterial invasion of epithelial cells
map05131  Shigellosis
map05135  Yersinia infection
map05142  Chagas disease
map05146  Amoebiasis
map05160  Hepatitis C
map05161  Hepatitis B
map05162  Measles
map05163  Human cytomegalovirus infection
map05164  Influenza A
map05165  Human papillomavirus infection
map05166  Human T-cell leukemia virus 1 infection
map05167  Kaposi sarcoma-associated herpesvirus infection
map05168  Herpes simplex virus 1 infection
map05169  Epstein-Barr virus infection
map05170  Human immunodeficiency virus 1 infection
map05171  Coronavirus disease - COVID-19
map05200  Pathways in cancer
map05203  Viral carcinogenesis
map05205  Proteoglycans in cancer
map05206  MicroRNAs in cancer
map05207  Chemical carcinogenesis - receptor activation
map05208  Chemical carcinogenesis - reactive oxygen species
map05210  Colorectal cancer
map05211  Renal cell carcinoma
map05212  Pancreatic cancer
map05213  Endometrial cancer
map05214  Glioma
map05215  Prostate cancer
map05218  Melanoma
map05220  Chronic myeloid leukemia
map05221  Acute myeloid leukemia
map05222  Small cell lung cancer
map05223  Non-small cell lung cancer
map05224  Breast cancer
map05225  Hepatocellular carcinoma
map05226  Gastric cancer
map05230  Central carbon metabolism in cancer
map05231  Choline metabolism in cancer
map05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
map05415  Diabetic cardiomyopathy
map05417  Lipid and atherosclerosis
map05418  Fluid shear stress and atherosclerosis
Reaction
R03362  ATP:1-phosphatidyl-1D-myo-inositol 3-phosphotransferase
R04545  ATP:1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate 3-phosphotransferase
R05795  ATP:1-phosphatidyl-1D-myo-inositol-4-phosphate 3-phosphotransferase
Disease
H00085  Agammaglobulinemias
H01370  SHORT syndrome
H01387  Activated PI3K-delta syndrome
H01885  Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04014 Ras signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04015 Rap1 signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04370 VEGF signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04630 JAK-STAT signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04668 TNF signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04066 HIF-1 signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04068 FoxO signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04070 Phosphatidylinositol signaling system
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04072 Phospholipase D signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04071 Sphingolipid signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04024 cAMP signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04151 PI3K-Akt signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04152 AMPK signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04150 mTOR signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
  09143 Cell growth and death
   04210 Apoptosis
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04218 Cellular senescence
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04550 Signaling pathways regulating pluripotency of stem cells
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04613 Neutrophil extracellular trap formation
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04620 Toll-like receptor signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04625 C-type lectin receptor signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04650 Natural killer cell mediated cytotoxicity
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04660 T cell receptor signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04662 B cell receptor signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04664 Fc epsilon RI signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04666 Fc gamma R-mediated phagocytosis
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04670 Leukocyte transendothelial migration
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04062 Chemokine signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
  09152 Endocrine system
   04910 Insulin signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04923 Regulation of lipolysis in adipocytes
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04929 GnRH secretion
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04915 Estrogen signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04914 Progesterone-mediated oocyte maturation
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04917 Prolactin signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04926 Relaxin signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04935 Growth hormone synthesis, secretion and action
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04919 Thyroid hormone signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
  09156 Nervous system
   04725 Cholinergic synapse
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04722 Neurotrophin signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
  09158 Development and regeneration
   04360 Axon guidance
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04380 Osteoclast differentiation
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
  09149 Aging
   04211 Longevity regulating pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04213 Longevity regulating pathway - multiple species
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05206 MicroRNAs in cancer
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05205 Proteoglycans in cancer
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05207 Chemical carcinogenesis - receptor activation
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05208 Chemical carcinogenesis - reactive oxygen species
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05203 Viral carcinogenesis
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05230 Central carbon metabolism in cancer
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05231 Choline metabolism in cancer
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
  09162 Cancer: specific types
   05210 Colorectal cancer
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05212 Pancreatic cancer
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05225 Hepatocellular carcinoma
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05226 Gastric cancer
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05214 Glioma
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05221 Acute myeloid leukemia
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05220 Chronic myeloid leukemia
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05218 Melanoma
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05211 Renal cell carcinoma
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05215 Prostate cancer
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05213 Endometrial cancer
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05224 Breast cancer
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05222 Small cell lung cancer
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05223 Non-small cell lung cancer
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05170 Human immunodeficiency virus 1 infection
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05161 Hepatitis B
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05160 Hepatitis C
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05171 Coronavirus disease - COVID-19
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05164 Influenza A
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05162 Measles
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05168 Herpes simplex virus 1 infection
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05163 Human cytomegalovirus infection
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05167 Kaposi sarcoma-associated herpesvirus infection
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05169 Epstein-Barr virus infection
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05165 Human papillomavirus infection
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
  09171 Infectious disease: bacterial
   05131 Shigellosis
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05135 Yersinia infection
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05100 Bacterial invasion of epithelial cells
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05142 Chagas disease
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05017 Spinocerebellar ataxia
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05020 Prion disease
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05418 Fluid shear stress and atherosclerosis
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05415 Diabetic cardiomyopathy
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04932 Non-alcoholic fatty liver disease
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04931 Insulin resistance
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04933 AGE-RAGE signaling pathway in diabetic complications
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   01524 Platinum drug resistance
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   01522 Endocrine resistance
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
Membrane trafficking [BR:ko04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
Genes
HSA: 5295(PIK3R1) 5296(PIK3R2) 8503(PIK3R3)
PTR: 455855(PIK3R2) 456565(PIK3R3) 461836(PIK3R1)
PPS: 100969981(PIK3R2) 100986080(PIK3R3) 100994315(PIK3R1)
GGO: 101129336(PIK3R3) 101130978(PIK3R1) 101135298(PIK3R2)
PON: 100173589(PIK3R1) 100174298(PIK3R3) 100437617(PIK3R2)
NLE: 100591270(PIK3R3) 100599301(PIK3R2) 100605788(PIK3R1)
HMH: 116462749(PIK3R1) 116473104(PIK3R3) 116478691(PIK3R2)
MCC: 698996(PIK3R1) 707310(PIK3R3) 719367(PIK3R2)
MCF: 101866246(PIK3R1) 102124804(PIK3R2) 102137291(PIK3R3)
MTHB: 126942202 126956531 126961422
MNI: 105475205(PIK3R1) 105488082(PIK3R2) 105494953(PIK3R3)
CSAB: 103222594(PIK3R1) 103224900(PIK3R3) 103234391(PIK3R2)
CATY: 105571321(PIK3R2) 105594576(PIK3R3) 105599262(PIK3R1)
PANU: 100510873(PIK3R1) 101002971(PIK3R3) 101009981(PIK3R2)
TGE: 112612001(PIK3R2) 112614522(PIK3R3) 112625914(PIK3R1)
MLEU: 105531763(PIK3R3) 105543389(PIK3R1) 105547376(PIK3R2)
RRO: 104662124(PIK3R3) 104675620(PIK3R1) 104680672(PIK3R2)
RBB: 108534276(PIK3R2) 108535636(PIK3R3) 108541175(PIK3R1)
TFN: 117065206(PIK3R1) 117075022(PIK3R2) 117092662(PIK3R3)
PTEH: 111539891(PIK3R1) 111548774(PIK3R3) 111554247(PIK3R2)
CANG: 105500411(PIK3R2) 105515019(PIK3R3) 105524169(PIK3R1)
CJC: 100392639(PIK3R1) 100406689(PIK3R2) 100414659(PIK3R3)
SBQ: 101032496(PIK3R1) 101033359(PIK3R2) 101050592(PIK3R3)
CIMI: 108284538(PIK3R2) 108295514(PIK3R1) 108312772(PIK3R3)
CSYR: 103262537(PIK3R1) 103272136(PIK3R3)
MMUR: 105855026(PIK3R2) 105877483(PIK3R3) 105881219(PIK3R1)
LCAT: 123634187 123639706(PIK3R2) 123648578(PIK3R1)
PCOQ: 105814042(PIK3R3) 105818191(PIK3R2) 105826612(PIK3R1)
OGA: 100949858(PIK3R1) 100952580(PIK3R3) 100956838(PIK3R2)
MMU: 18708(Pik3r1) 18709(Pik3r2) 18710(Pik3r3)
MCAL: 110292624 110299855(Pik3r2) 110308009(Pik3r1)
MPAH: 110322865(Pik3r3) 110328811(Pik3r1) 110336420(Pik3r2)
RNO: 25513(Pik3r1) 29741(Pik3r2) 60664(Pik3r3)
MCOC: 116069491(Pik3r2) 116083721(Pik3r1) 116096465(Pik3r3)
ANU: 117708961 117721973(Pik3r2) 117723761(Pik3r1)
MUN: 110549145(Pik3r2) 110553683(Pik3r1) 110563512(Pik3r3)
CGE: 100750761(Pik3r1) 100771181(Pik3r2) 100774067
MAUA: 101829045(Pik3r2) 101831400 101835039(Pik3r1)
PROB: 127217216(Pik3r2) 127220972(Pik3r1) 127225197(Pik3r3)
PLEU: 114688966(Pik3r2) 114703850(Pik3r1) 114706924(Pik3r3)
MORG: 121448002 121455952(Pik3r1) 121462841(Pik3r2)
AAMP: 119808979(Pik3r1) 119812102(Pik3r2) 119817743
NGI: 103726879(Pik3r2) 103730305(Pik3r3) 103738715(Pik3r1)
HGL: 101703691(Pik3r1) 101717096(Pik3r3) 101718815(Pik3r2)
CPOC: 100730242(Pik3r1) 100734044(Pik3r2) 100734206
CCAN: 109682432(Pik3r3) 109682554 109694666(Pik3r1)
DORD: 105985370(Pik3r1) 105986178(Pik3r3)
DSP: 122100872(Pik3r2) 122108047 122117343(Pik3r1)
PLOP: 125348916(Pik3r2) 125355095(Pik3r3) 125367817(Pik3r1)
MMMA: 107139438(Pik3r1) 107141811(Pik3r3) 107145061(Pik3r2)
OPI: 101517982(PIK3R1) 101528030 101532354(PIK3R2)
TUP: 102469401(PIK3R2) 102484444(PIK3R3) 102484500(PIK3R1)
GVR: 103585463(PIK3R3) 103593683(PIK3R2) 103608454(PIK3R1)
CFA: 100856339 487235(PIK3R1) 609956(PIK3R2)
CLUD: 112642563(PIK3R3) 112660199(PIK3R1) 112666735(PIK3R2)
VVP: 112913170(PIK3R2) 112914774 112935820(PIK3R1)
VLG: 121481416 121494738(PIK3R2) 121496480(PIK3R1)
NPO: 129513452(PIK3R1) 129520803(PIK3R3) 129522073(PIK3R2)
AML: 100467916(PIK3R3) 100475291(PIK3R2) 100483828(PIK3R1)
UMR: 103663617(PIK3R1) 103670766(PIK3R3) 103675162(PIK3R2)
UAH: 113254730(PIK3R3) 113255266(PIK3R1) 113256705(PIK3R2)
UAR: 123779926(PIK3R2) 123793748(PIK3R3) 123800228(PIK3R1)
MPUF: 101680399(PIK3R2) 101683594 101683710(PIK3R1)
MNP: 132000809(PIK3R3) 132011173(PIK3R2) 132028693(PIK3R1)
MLK: 131810162(PIK3R3) 131823754(PIK3R2) 131832309(PIK3R1)
NVS: 122899916(PIK3R3) 122909588(PIK3R2) 122918946(PIK3R1)
ORO: 101370100(PIK3R1) 101371800(PIK3R2) 101374787(PIK3R3)
EJU: 114224308 114224631(PIK3R1) 114226659(PIK3R2)
ZCA: 113911688(PIK3R3) 113917179(PIK3R2) 113928897(PIK3R1)
MLX: 118006042(PIK3R2) 118016863(PIK3R1) 118019468(PIK3R3)
NSU: 110574558(PIK3R2) 110575009 110591287(PIK3R1)
LWW: 102726443(PIK3R2) 102728383 102751021(PIK3R1)
FCA: 100271864(PIK3R1) 101093286 101093586(PIK3R2)
PYU: 121011002(PIK3R2) 121014969(PIK3R1) 121027050(PIK3R3)
PCOO: 112861619(PIK3R1) 112868847
PBG: 122480440(PIK3R3) 122487093(PIK3R2) 122489641(PIK3R1)
PVIV: 125150373(PIK3R2) 125161995(PIK3R1) 125172124(PIK3R3)
PTG: 102949853(PIK3R3) 102952993(PIK3R1) 102967709(PIK3R2)
PPAD: 109247606(PIK3R2) 109266953(PIK3R3) 109275060(PIK3R1)
HHV: 120219997(PIK3R1) 120239233(PIK3R2) 120247089
BTA: 282307(PIK3R1) 282308(PIK3R2) 286865(PIK3R3)
BOM: 102266922(PIK3R1) 102280296(PIK3R3) 102286868(PIK3R2)
BIU: 109556345 109561418(PIK3R2) 109574805(PIK3R1)
BBUB: 102395384 102404517(PIK3R2) 102415109(PIK3R1)
BBIS: 104992716 104994333(PIK3R3) 104998445(PIK3R1)
CHX: 102170135(PIK3R2) 102179343(PIK3R3) 102188710(PIK3R1)
OAS: 101111546(PIK3R2) 101121455(PIK3R1) 101123247(PIK3R3)
BTAX: 128044474(PIK3R3) 128050540(PIK3R2) 128066235(PIK3R1)
ODA: 120856226 120864210(PIK3R2) 120879604(PIK3R1)
CCAD: 122437038(PIK3R3) 122440740(PIK3R2) 122454626(PIK3R1)
MBEZ: 129540801(PIK3R3) 129553207(PIK3R1) 129559156(PIK3R2)
SSC: 100511937 100623707(PIK3R1) 100739510(PIK3R2)
CFR: 102505690 102513205(PIK3R2) 102520923(PIK3R1)
CBAI: 105064416(PIK3R1) 105065663(PIK3R3) 105082679(PIK3R2)
CDK: 105084758(PIK3R1) 105092913 105101867(PIK3R2)
VPC: 102532395(PIK3R1) 102536225 102536302(PIK3R2)
BACU: 103007464(PIK3R1) 103008077(PIK3R3) 103009307(PIK3R2)
BMUS: 118891709(PIK3R1) 118892996(PIK3R2) 118901944
LVE: 103070370(PIK3R1) 103078725(PIK3R3) 103083960(PIK3R2)
OOR: 101277568(PIK3R3) 101281352(PIK3R2) 101285437(PIK3R1)
DLE: 111166652(PIK3R2) 111175760 111185984(PIK3R1)
PCAD: 102975555(PIK3R3) 102991192(PIK3R1) 102991779(PIK3R2)
PSIU: 116742613 116750604(PIK3R1) 116751944(PIK3R2)
NASI: 112400438 112404930(PIK3R1) 112414874(PIK3R2)
ECB: 100050227(PIK3R1) 100052122 100146348(PIK3R2)
EPZ: 103548220(PIK3R1) 103551868(PIK3R3) 103561550(PIK3R2)
EAI: 106822593 106824993(PIK3R2) 106840141(PIK3R1)
MYB: 102242302(PIK3R1) 102253405(PIK3R2) 102258430(PIK3R3)
MYD: 102753036(PIK3R1) 102760468(PIK3R3) 102763670(PIK3R2)
MMYO: 118656203(PIK3R1) 118657573(PIK3R2) 118675217
MLF: 102419324 102426106(PIK3R3) 102427890(PIK3R1) 102429230(PIK3R2) 102441522
PKL: 118703803(PIK3R1) 118722550 118725879(PIK3R2)
EFUS: 103294784(PIK3R3) 103299551(PIK3R2) 103305161(PIK3R1)
MNA: 107526728(PIK3R3) 107529317(PIK3R1) 107535325(PIK3R2)
DRO: 112305224(PIK3R2) 112314466 112321016(PIK3R1)
SHON: 118975178(PIK3R2) 118982454(PIK3R3) 118998595(PIK3R1)
AJM: 119046830(PIK3R2) 119052227 119053288(PIK3R1)
PDIC: 114496100(PIK3R3) 114501063(PIK3R1) 114502559(PIK3R2)
PHAS: 123824527(PIK3R1) 123828291(PIK3R2) 123832298
MMF: 118616460(PIK3R2) 118626685 118642883(PIK3R1)
PPAM: 129069407(PIK3R3) 129074590(PIK3R1) 129074969(PIK3R2)
HAI: 109373811(PIK3R3) 109382484(PIK3R2) 109395865(PIK3R1)
RFQ: 117024531(PIK3R1) 117027160 117038261(PIK3R2)
PALE: 102879163(PIK3R1) 102879453(PIK3R2) 102891637
PGIG: 120606549(PIK3R2) 120608247(PIK3R1) 120620206
PVP: 105296605(PIK3R2) 105297140 105299371(PIK3R1)
RAY: 107498704(PIK3R1) 107517899(PIK3R3) 107521668(PIK3R2)
MJV: 108383561(PIK3R2) 108390475(PIK3R1) 108395975
TOD: 119237093(PIK3R3) 119241117(PIK3R2) 119260810(PIK3R1)
SARA: 101540938(PIK3R2) 101541868(PIK3R1) 101547106(PIK3R3)
SETR: 126001552(PIK3R1) 126011086(PIK3R3) 126030200(PIK3R2)
LAV: 100653731(PIK3R1) 100665045(PIK3R2) 100675496(PIK3R3)
ETF: 101655654(PIK3R1) 101657368 101659995(PIK3R2)
DNM: 101423744 101433347(PIK3R2) 101435351(PIK3R1)
MDO: 100019317(PIK3R1) 100032726(PIK3R2) 100616957(PIK3R3)
SHR: 100924976(PIK3R1) 100926892(PIK3R2) 100935230(PIK3R3)
PCW: 110209293(PIK3R3) 110216530(PIK3R1) 110223395(PIK3R2)
OAA: 100080187(PIK3R2) 100082075(PIK3R3) 103167126(PIK3R1)
GGA: 427171(PIK3R1) 429096(PIK3R3) 771142(PIK3R2)
PCOC: 116234220 116235709(PIK3R2) 116239922(PIK3R1)
CJO: 107305909(PIK3R1) 107317608 107325533(PIK3R2)
TPAI: 128072383(PIK3R3) 128074427(PIK3R1) 128088982(PIK3R2)
LMUT: 125685084(PIK3R2) 125686542(PIK3R1) 125694122(PIK3R3)
NMEL: 110388756(PIK3R2) 110389564(PIK3R1) 110402756(PIK3R3)
APLA: 101795759 101799717(PIK3R1) 101803461(PIK3R2)
ACYG: 106033049(PIK3R3) 106042106(PIK3R1) 106045000(PIK3R2)
CATA: 118243598(PIK3R3) 118251494(PIK3R1) 118258749(PIK3R2)
AFUL: 116491758 116499089(PIK3R2) 116501170(PIK3R1)
TGU: 100221185 100223949(PIK3R1) 100226234(PIK3R2)
LSR: 110469696 110472594(PIK3R1) 110478008(PIK3R2)
SCAN: 103814989 103821918(PIK3R2) 103823133(PIK3R1) 115483908
PMOA: 120498082(PIK3R2) 120502343(PIK3R1) 120503174
OTC: 121341222(PIK3R1) 121341824(PIK3R2) 121344995
PRUF: 121355311(PIK3R1) 121361353(PIK3R2) 121361937
GFR: 102032353(PIK3R1) 102035891(PIK3R2) 102039817(PIK3R3)
FAB: 101811808(PIK3R2) 101812251(PIK3R3) 101820843(PIK3R1)
OMA: 130256118(PIK3R3) 130264528(PIK3R2) 130265049(PIK3R1)
PHI: 102106897(PIK3R2) 102112482(PIK3R3) 102114750(PIK3R1)
PMAJ: 107208273 107215603(PIK3R2) 107216262(PIK3R1)
CCAE: 111933104(PIK3R3) 111940405(PIK3R2) 111941370(PIK3R1)
CCW: 104686712(PIK3R1) 104695234 104696977(PIK3R2)
CBRC: 103621908(PIK3R3) 103622106(PIK3R2) 103624307(PIK3R1)
ZAB: 102060529(PIK3R2) 102070553(PIK3R1) 102072114
ZLE: 135451300(PIK3R3) 135458779(PIK3R2) 135459365(PIK3R1)
ACHL: 103800635(PIK3R3) 103807634(PIK3R2) 103807943(PIK3R1)
SVG: 106850601(PIK3R3) 106856206(PIK3R1) 106857134(PIK3R2)
MMEA: 130572286 130582513 130586288(PIK3R2) 130589279(PIK3R3)
HRT: 120756367(PIK3R3) 120763569(PIK3R2) 120765192(PIK3R1)
FPG: 101913266(PIK3R3) 101915242(PIK3R2) 101924523(PIK3R1)
FCH: 102056135(PIK3R1) 102057083(PIK3R2) 102059517
CLV: 102084272(PIK3R3) 102084904(PIK3R2) 102092838(PIK3R1)
EGZ: 104124880(PIK3R1) 104126253(PIK3R3) 104135641(PIK3R2)
NNI: 104015409(PIK3R3) 104018715(PIK3R2)
PCRI: 104027580(PIK3R3) 104038243(PIK3R1)
PLET: 104621033(PIK3R2) 104623180(PIK3R3)
EHS: 104504642(PIK3R1) 104508880(PIK3R3) 104512091(PIK3R2)
PCAO: 104044331(PIK3R1) 104051690
ACUN: 113483193 113489298(PIK3R2) 113489600(PIK3R1)
TALA: 104363088(PIK3R1) 104365196(PIK3R2) 104366887
PADL: 103919124(PIK3R3) 103919717(PIK3R1) 103926435(PIK3R2)
AFOR: 103893369(PIK3R1) 103899302(PIK3R2) 103905595(PIK3R3)
ACHC: 115337134(PIK3R1) 115348975 115349575(PIK3R2) 121233034
HALD: 104315723(PIK3R3) 104319651(PIK3R1) 104323052
HLE: 104828487(PIK3R2) 104839910(PIK3R1) 104841050(PIK3R3)
CCRI: 104158448(PIK3R3) 104160278(PIK3R2) 104169467(PIK3R1)
CSTI: 104553746(PIK3R1) 104559613(PIK3R3)
CMAC: 104478394(PIK3R3) 104478819(PIK3R1)
MUI: 104542097(PIK3R3) 104543772(PIK3R2) 104544758(PIK3R1)
BREG: 104634362 104634486(PIK3R1) 104641031(PIK3R3) 104643797
FGA: 104071302(PIK3R1) 104072668(PIK3R2) 104083214(PIK3R3)
GSTE: 104257515(PIK3R1) 104259647(PIK3R3) 104262659
LDI: 104341169(PIK3R3) 104350040(PIK3R1) 104350597(PIK3R2)
MNB: 103768794(PIK3R3) 103776111(PIK3R1)
OHA: 104330905(PIK3R1) 104339461(PIK3R2) 104339506(PIK3R3)
NNT: 104403579(PIK3R3) 104410866(PIK3R1) 104413180
SHAB: 115611400 115618216(PIK3R2) 115619483(PIK3R1)
DPUB: 104300791(PIK3R2) 104301577(PIK3R3) 104306691(PIK3R1)
PGUU: 104459755(PIK3R1) 104462451(PIK3R3) 104470133
ACAR: 104523932(PIK3R1) 104526170 104528001(PIK3R3)
CPEA: 104388868(PIK3R2) 104395652(PIK3R1) 104396688(PIK3R3)
AVIT: 104271453(PIK3R1) 104273204 104277649(PIK3R3)
CVF: 104285739(PIK3R1) 104286266(PIK3R3) 104290423 104295401(PIK3R2)
RTD: 128900619(PIK3R2) 128902186(PIK3R1) 128913752(PIK3R3)
CUCA: 104060172(PIK3R3) 104060960(PIK3R2) 104064011(PIK3R1)
TEO: 104372178 104374535(PIK3R1) 104382213(PIK3R3)
BRHI: 104495015(PIK3R1) 104499813 104502170(PIK3R3)
AAM: 106485939(PIK3R3) 106495610(PIK3R2) 106499441(PIK3R1)
AROW: 112966717(PIK3R2) 112969925(PIK3R1) 112976037
NPD: 112942696 112943951(PIK3R2) 112945237(PIK3R1)
TGT: 104574053(PIK3R3) 104575770(PIK3R1) 104577735
DNE: 112985410 112986570(PIK3R2) 112987101(PIK3R1)
SCAM: 104145800(PIK3R2) 104147993(PIK3R3) 104152968(PIK3R1)
ASN: 102377899(PIK3R2) 102380057 102382060(PIK3R1)
AMJ: 102567863(PIK3R2) 102570922(PIK3R1) 106737141(PIK3R3)
CPOO: 109307425(PIK3R3) 109307980(PIK3R1) 109312353(PIK3R2)
GGN: 109286709(PIK3R3) 109294997(PIK3R2) 109297752(PIK3R1)
PSS: 102449585(PIK3R1) 102457516
CMY: 102933845(PIK3R2) 102941819 102945631(PIK3R1)
CCAY: 125626958(PIK3R2) 125636597(PIK3R1) 125640830(PIK3R3)
DCC: 119848340(PIK3R2) 119855572(PIK3R1) 119859766
CPIC: 101945673(PIK3R2) 101947423 101953817(PIK3R1)
TST: 117868848(PIK3R2) 117879552(PIK3R1) 117881251
CABI: 116826231(PIK3R2) 116839230 116839322(PIK3R1)
MRV: 120370714 120391575(PIK3R2) 120407838(PIK3R1)
ACS: 100554618(pik3r3) 100555182(pik3r2) 100556883(pik3r1)
ASAO: 132767034(PIK3R1) 132773868(PIK3R3) 132780959(PIK3R2)
PVT: 110072561(PIK3R2) 110073778(PIK3R3) 110073951(PIK3R1)
SUND: 121923252(PIK3R1) 121928626
PBI: 103055280(PIK3R2) 103065132 103065975(PIK3R1)
PMUR: 107282273(PIK3R2) 107283596 107286152(PIK3R1)
CTIG: 120297322 120305981(PIK3R2) 120318076(PIK3R1)
TSR: 106538977(PIK3R1) 106543200(PIK3R3) 106552169
PGUT: 117664160(PIK3R3) 117677371(PIK3R2) 117679253(PIK3R1)
APRI: 131188166(PIK3R2) 131191378(PIK3R1) 131196302(PIK3R3)
PTEX: 113434955(PIK3R2) 113440623 113447320(PIK3R1)
NSS: 113410978 113413935(PIK3R1) 113414090(PIK3R2)
VKO: 123029047 123031202(PIK3R1)
PMUA: 114588236(PIK3R2) 114599062 114606162(PIK3R1)
PRAF: 128405629(PIK3R2) 128415836(PIK3R3) 128423036(PIK3R1)
ZVI: 118077038(PIK3R1) 118085906(PIK3R2) 118088990
HCG: 128324386(PIK3R3) 128344776(PIK3R1) 128346633(PIK3R2)
GJA: 107108905(PIK3R1) 107119473(PIK3R3) 107121678(PIK3R2)
STOW: 125432754 125433242(PIK3R3) 125436164(PIK3R1)
EMC: 129329994(PIK3R2) 129331257(PIK3R3) 129334239(PIK3R1)
XLA: 108706884(pik3r2.S) 108713027(pik3r2.L) 399202(pik3r1.S) 443964(pik3r1.L) 446786(pik3r3.S) 447594(pik3r3.L)
XTR: 100486835(pik3r1) 100497001(pik3r2) 549983(pik3r3)
NPR: 108789013(PIK3R2) 108797628(PIK3R1) 108802963
RTEM: 120916053(PIK3R2) 120923203 120928855(PIK3R1)
BBUF: 120978688(PIK3R3) 120989607(PIK3R2) 120992399(PIK3R1)
BGAR: 122924744(PIK3R1) 122946211(PIK3R2)
MUO: 115463034(PIK3R1) 115471738 115480521(PIK3R2)
GSH: 117346336 117353683(PIK3R1) 117365925(PIK3R2)
DRE: 100000252(pik3r3b) 404211(pik3r2) 557176(pik3r1)
PTET: 122344708(pik3r1) 122346452(pik3r3b) 122347155 122362518(pik3r2)
LROH: 127164849(pik3r1) 127166520(pik3r3b) 127176088(pik3r2)
OMC: 131540458(pik3r1) 131541975(pik3r3b) 131552189(pik3r2)
PPRM: 120460087(pik3r3b) 120468781(pik3r3a) 120468782 120472399(pik3r1) 120482851(pik3r2)
RKG: 130070871(pik3r2) 130091371 130099701(pik3r1)
MAMB: 125250270(pik3r3a) 125250735(pik3r2) 125267879(pik3r1) 125273996(pik3r3b)
TROS: 130555087(pik3r2) 130556269(pik3r3b) 130566832(pik3r1)
TDW: 130417757(pik3r2) 130418890(pik3r1) 130424413(pik3r3b)
MANU: 129441166(pik3r1) 129442260(pik3r2) 129451059(pik3r3b)
IPU: 108260231 108272037(pik3r3b)
IFU: 128603480(pik3r1) 128614576(pik3r3b)
PHYP: 113531632(pik3r1) 113538265
SMEO: 124379064(pik3r1) 124392406(pik3r3b)
TFD: 113641408(pik3r1) 113647639(pik3r3b)
TVC: 132840612(pik3r1) 132844284(pik3r3b)
TRN: 134303620(pik3r1) 134317232(pik3r3b)
AMEX: 103029972(pik3r3) 103035767 103046618(pik3r1) 111190801
CMAO: 118808170(pik3r3b) 118814571(pik3r1)
CHAR: 105896427 105900602(pik3r2) 105902185(pik3r1) 105913142(pik3r3b) 122129273 122133228
TFS: 130517020(pik3r1) 130525966 130528394 130528931(pik3r3b) 130538567 130539592(pik3r2)
PGEO: 117445092(pik3r3b) 117445659 117455737(pik3r1) 117462047(pik3r2) 117462274
GACU: 117532612(pik3r2) 117535004 117542274 117545568 117560597(pik3r3b) 117561441(pik3r1)
EMAC: 134865729 134865816(pik3r2) 134868191(pik3r1) 134869270(pik3r3b) 134869506 134873278
ELY: 117252529 117254143 117254148(pik3r3b) 117269552(pik3r1) 117271502 117271508(pik3r2)
EFO: 125890643 125895325(pik3r3b) 125896428 125901675(pik3r2) 125902071 125905500(pik3r1)
PLEP: 121938061 121939825 121951302 121951926(pik3r2) 121959511(pik3r1) 121962939(pik3r3b)
SLUC: 116037246(pik3r2) 116045807 116053059 116056635 116056995(pik3r3b) 116062801(pik3r1)
ECRA: 117944918 117950300 117950796(pik3r3b) 117953620(pik3r2) 117954000 117959815(pik3r1)
GAT: 120815842(pik3r2) 120816124 120823475 120823622(pik3r3b) 120830750 120831616(pik3r1)
PPUG: 119209332(pik3r2) 119209420 119216917 119216976(pik3r3b) 119224672 119226302(pik3r1)
AFB: 129094332(pik3r3b) 129094609 129101175 129102021(pik3r1) 129110782(pik3r2) 129112007
CLUM: 117729683(pik3r3b) 117729698 117736025 117740185(pik3r1) 117746515 117746960(pik3r2)
PSWI: 130193807(pik3r3b) 130194122 130196195 130197660 130197673(pik3r2) 130205168(pik3r1)
MSAM: 119891547 119900224(pik3r3b) 119900503 119902234(pik3r2) 119902368 119914041(pik3r1)
SCHU: 122865334(pik3r1) 122876770 122877580(pik3r3b) 122878127 122887224(pik3r2) 122887535
CUD: 121509697 121512025(pik3r3b) 121512376 121519790 121519794(pik3r2) 121524754(pik3r1)
ALAT: 119011069 119011087(pik3r2) 119019184 119028110 119028425(pik3r3b) 119029893(pik3r1)
CSAI: 133451344 133452923(pik3r2) 133453078 133455087(pik3r1) 133457924(pik3r3b) 133458551
PRET: 103463201(pik3r3) 103463319 103470780 103473324(pik3r1) 103478998 103479173(pik3r2)
GMU: 124869460(pik3r2) 124870480 124872596(pik3r1) 124873683 124873763(pik3r3b) 124877742
KMR: 108234365 108238336 108244850(pik3r2) 108245882 108247561(pik3r3b) 108250884(pik3r1)
MCEP: 124996387(pik3r1) 125009281(pik3r3b) 125009744 125010445(pik3r2) 125011199 125012779
HHIP: 117760130(pik3r3b) 117760625 117768381 117771255(pik3r1) 117777997(pik3r2) 117778159
HSP: 118114686 118117905 118117936(pik3r2) 118120902 118120979(pik3r3b) 118125392(pik3r1)
PPLT: 128438364 128448214 128448269(pik3r3b) 128454882 128455193(pik3r2) 128462281(pik3r1)
SMAU: 118284803(pik3r1) 118310786(pik3r2) 118311687 118313435 118317729(pik3r3b) 118318227
XGL: 120790713 120791111(pik3r3b) 120799080(pik3r2) 120799460 120805057 120806252(pik3r1)
MALB: 109957384 109965201(pik3r3) 109966856 109969301(pik3r2) 109969763(pik3r1) 109970672
BSPL: 114844064 114845055(pik3r2) 114854767(pik3r3b) 114854785 114861410 114866713(pik3r1)
PKI: 111834821(pik3r3) 111835615(pik3r1) 111847640 111856594 111860386(pik3r2)
AANG: 118206252 118212644(pik3r1) 118225456(pik3r2) 118225588(pik3r3b) 118228853
LOC: 102687995(pik3r2) 102693436(pik3r3) 102696821(pik3r1)
PSEX: 120514216(pik3r3b) 120532558(pik3r1) 120537570(pik3r2)
LCM: 102348007(PIK3R3) 102353218(PIK3R1)
RTP: 109916739 109917303(pik3r3b)
CPLA: 122558110(pik3r1)
HOC: 132819107(pik3r3b) 132822331(pik3r1)
LERI: 129695104 129700904(pik3r3b)
PMRN: 116948911
LRJ: 133352049
BFO: 118432571
BBEL: 109475961
CIN: 100184893
SCLV: 120335427
SPU: 588766
LPIC: 129270766
APLC: 110977729
SKO: 100372481
DME: Dmel_CG2699(Pi3K21B)
DER: 6543312
DSE: 6621105
DSI: Dsimw501_GD23016(Dsim_GD23016)
DSR: 110187562
DPO: 4817932
DPE: 6593764
DMN: 108163765
DWI: 6651829
DGR: 6562048
DAZ: 108609449
DNV: 108650034
DHE: 111602464
DVI: 6628686
CCAT: 101450793
BOD: 106614981
BDR: 105229287
AOQ: 129247242
TDA: 119688989
MDE: 101896300
SCAC: 106081749
LCQ: 111686430
LSQ: 119611134
GFS: 119633187
CLON: 129613108
ACOZ: 120953852
AARA: 120897556
AMER: 121592513
ASTE: 118512835
AFUN: 125770071
AMOU: 128300726
AAG: 5578257
AALB: 109409609
ASUA: 134210579
CPII: 120413155
CNS: 116337413
BCOO: 119085220
AME: 408577
ACER: 107993600
ALAB: 122719497
ADR: 102674501
AFLR: 100869097
BIM: 100743083
BBIF: 117209300
BVK: 117237500
BVAN: 117156020
BTER: 100643962
BAFF: 126919609
BPYO: 122565623
BPAS: 132910786
FVI: 122536883
CCAL: 108629871
OBB: 114871807
OLG: 117600869
MGEN: 117229216
NMEA: 116432267
CGIG: 122399909
SOC: 105195470
MPHA: 105831984
AEC: 105151922
ACEP: 105620878
PBAR: 105430848
VEM: 105567561
HST: 105192434
DQU: 106748226
CFO: 105255336
LHU: 105667777
PGC: 109854747
OBO: 105284404
PCF: 106792271
PFUC: 122514468
VPS: 122629872
VCRB: 124425716
VVE: 124949563
NVI: 100122747
CSOL: 105361583
LHT: 122509398
LBD: 127288195
MDL: 103580680
CGLO: 123259870
FAS: 105268850
DAM: 107037299
DSM: 124410830
NPT: 124220654
NFB: 124183956
NLO: 107219243
NVG: 124306415
TCA: 100141888
DPA: 109540864
SOY: 115876841
AGRG: 126748963
ATD: 109595073
AGB: 108916999
LDC: 111507049
DVV: 114340898
NVL: 108559788
PPYR: 116166071
OTU: 111425557
BMOR: 100158253(Pi3k60)
BMAN: 114245941
MSEX: 115453059
BANY: 112044673
MJU: 123869620
NIQ: 126771312
VCD: 124531686
MCIX: 123655842
PMAC: 106714800
PPOT: 106106684
PXU: 106127430
PRAP: 110992252
PBX: 123717367
PNAP: 125055262
ZCE: 119834537
CCRC: 123693845
LSIN: 126965472
AAGE: 121739614
HAW: 110370679
HZE: 124629583
TNL: 113497575
SLIU: 111348252
OFU: 114365514
ATRA: 106129178
PXY: 105388447
PGW: 126368434
LGLY: 125226511
CCRN: 123302198
AGS: 114129704
RMD: 113553291
ACOO: 126838240
BTAB: 109032766
CLEC: 106664096
HHAL: 106692677
NLU: 111047698
HVI: 124369941
FOC: 113201758
TPAL: 117651645
FCD: 110845224
PVM: 113810630
PCHN: 125038179
PMOO: 119586926
HAME: 121864257
PCLA: 123745389
CQD: 128685383
PTRU: 123499232
ESN: 126990852
MNZ: 135210751
HAZT: 108677079
EAF: 111697024
LSM: 121114447
TCF: 131893673
PPOI: 119110593
DSV: 119433196
RSAN: 119404584
RMP: 119181020
VDE: 111248584
VJA: 111273172
DPTE: 113798240
PMEO: 129591294
CEL: CELE_Y110A7A.10(aap-1)
CBR: CBG_10815(Cbr-aap-1)
BMY: BM_BM7280(Bma-aap-1)
TSP: Tsp_02388
BGT: 106064965
CRG: 105321629
CVN: 111118072
CANU: 128165077
OED: 125669491
OBI: 106879157
OSN: 115223514
LJP: 135470408
EGL: EGR_06563
LLON: 135486959
NVE: 5520340
EPA: 110239539
ATEN: 116307342
ADF: 107335159
AMIL: 114952874
PDAM: 113679985
SPIS: 111326832
DGT: 114527321
XEN: 124440213
HSY: 130630392
 » show all
Reference
PMID:1849461
  Authors
Skolnik EY, Margolis B, Mohammadi M, Lowenstein E, Fischer R, Drepps A, Ullrich A, Schlessinger J
  Title
Cloning of PI3 kinase-associated p85 utilizing a novel method for expression/cloning of target proteins for receptor tyrosine kinases.
  Journal
Cell 65:83-90 (1991)
DOI:10.1016/0092-8674(91)90410-Z
  Sequence
[hsa:5295]
Reference
PMID:9582025
  Authors
Janssen JW, Schleithoff L, Bartram CR, Schulz AS
  Title
An oncogenic fusion product of the phosphatidylinositol 3-kinase p85beta subunit and HUMORF8, a putative deubiquitinating enzyme.
  Journal
Oncogene 16:1767-72 (1998)
DOI:10.1038/sj.onc.1201695
  Sequence
[hsa:5296]
Reference
PMID:9524259
  Authors
Dey BR, Furlanetto RW, Nissley SP
  Title
Cloning of human p55 gamma, a regulatory subunit of phosphatidylinositol 3-kinase, by a yeast two-hybrid library screen with the insulin-like growth factor-I receptor.
  Journal
Gene 209:175-83 (1998)
DOI:10.1016/S0378-1119(98)00045-6
  Sequence
[hsa:8503]
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