KEGG Orthology (KO)

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 09100 Metabolism
 
 09120 Genetic Information Processing
 
 09130 Environmental Information Processing
 
 09140 Cellular Processes
 
 09150 Organismal Systems
 
   09151 Immune system
     04640 Hematopoietic cell lineage [PATH:ko04640]
     04610 Complement and coagulation cascades [PATH:ko04610]
     04611 Platelet activation [PATH:ko04611]
     04613 Neutrophil extracellular trap formation [PATH:ko04613]
     04620 Toll-like receptor signaling pathway [PATH:ko04620]
     04624 Toll and Imd signaling pathway [PATH:ko04624]
     04621 NOD-like receptor signaling pathway [PATH:ko04621]
       K08727  NOD1, CARD4; nucleotide-binding oligomerization domain-containing protein 1
       K08846  RIPK2; receptor-interacting serine/threonine-protein kinase 2 [EC:2.7.11.1]
       K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
       K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K02581  NFKBIB; NF-kappa-B inhibitor beta
       K04734  NFKBIA; NF-kappa-B inhibitor alpha
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04735  RELA; transcription factor p65
       K04519  IL1B; interleukin 1 beta
       K05482  IL18, IL1F4; interleukin 18
       K05405  IL6; interleukin 6
       K03156  TNF, TNFA; tumor necrosis factor superfamily, member 2
       K10030  IL8, CXCL8; interleukin 8
       K05505  CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
       K14624  CCL2, MCP1; C-C motif chemokine 2
       K12499  CCL5; C-C motif chemokine 5
       K13916  CAMP, LL37; cathelicidin antimicrobial peptide
       K05230  DEFA; defensin, alpha
       K21100  DEFB4; beta-defensin 4
       K23126  DEFB103; beta-defensin 103
       K10165  NOD2, CARD15; nucleotide-binding oligomerization domain-containing protein 2
       K04427  MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
       K04403  MAP3K7IP1, TAB1; TAK1-binding protein 1
       K04404  MAP3K7IP2, TAB2; TAK1-binding protein 2
       K12793  MAP3K7IP3, TAB3; TAK1-binding protein 3
       K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
       K04441  P38; p38 MAP kinase [EC:2.7.11.24]
       K04448  JUN; transcription factor AP-1
       K17890  ATG16L1; autophagy-related protein 16-1
       K08339  ATG5; autophagy-related protein 5
       K08336  ATG12; ubiquitin-like protein ATG12
       K08341  GABARAP, ATG8, LC3; GABA(A) receptor-associated protein
       K10435  MAP1LC; microtubule-associated protein 1 light chain
       K12795  SUGT1, SGT1; suppressor of G2 allele of SKP1
       K20894  SHARPIN; shank-associated RH domain-interacting protein
       K10630  RBCK1, HOIL1; RanBP-type and C3HC4-type zinc finger-containing protein 1 [EC:2.3.2.31]
       K11974  RNF31, HOIP; E3 ubiquitin-protein ligase RNF31 [EC:2.3.2.31]
       K04725  XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
       K12797  CARD6; caspase recruitment domain-containing protein 6
       K12792  TRIP6; thyroid receptor-interacting protein 6
       K12796  ERBIN, ERBB2IP; erbb2-interacting protein
       K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
       K03173  TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
       K09849  TRAF5; TNF receptor-associated factor 5
       K03175  TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
       K12794  CARD9; caspase recruitment domain-containing protein 9
       K11859  TNFAIP3, A20, OTUD7C; tumor necrosis factor, alpha-induced protein 3 [EC:3.4.19.12]
       K12648  MAVS, IPS1; mitochondrial antiviral-signaling protein
       K03174  TRAF3; TNF receptor-associated factor 3
       K05410  TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
       K07211  IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
       K12650  TANK; TRAF family member-associated NF-kappa-B activator
       K05411  IRF3; interferon regulatory factor 3
       K09447  IRF7; interferon regulatory factor 7
       K05414  IFNA; interferon alpha
       K05415  IFNB; interferon beta
       K12653  NLRX1; NLR family member X1
       K08645  lef; anthrax lethal toxin endopeptidase [EC:3.4.24.83]
       K11030  pagA; protective antigen
       K20909  ANTXR; anthrax toxin receptor
       K12798  NLRP1, CARD7; NACHT, LRR and PYD domains-containing protein 1
       K12799  PYCARD, ASC; apoptosis-associated speck-like protein containing a CARD
       K01370  CASP1; caspase 1 [EC:3.4.22.36]
       K02161  BCL2; apoptosis regulator Bcl-2
       K04570  BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
       K01363  CTSB; cathepsin B [EC:3.4.22.1]
       K12800  NLRP3, PYPAF1; NACHT, LRR and PYD domains-containing protein 3
       K03443  PANX1; pannexin 1
       K05220  P2RX7; P2X purinoceptor 7
       K04977  TRPM2; transient receptor potential cation channel subfamily M member 2 [EC:3.6.1.13]
       K04982  TRPM7, CHAK1; transient receptor potential cation channel subfamily M member 7 [EC:2.7.11.1]
       K04971  TRPV2; transient receptor potential cation channel subfamily V member 2
       K04612  CASR; calcium-sensing receptor
       K04622  GPRC6A; G protein-coupled receptor family C group 6 member A
       K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
       K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
       K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
       K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
       K05862  VDAC1; voltage-dependent anion channel protein 1
       K15040  VDAC2; voltage-dependent anion channel protein 2
       K15041  VDAC3; voltage-dependent anion channel protein 3
       K20858  MCU; calcium uniporter protein, mitochondrial
       K14216  OAS; 2'-5'-oligoadenylate synthetase [EC:2.7.7.84]
       K01165  RNASEL; ribonuclease L
       K17820  DHX33; ATP-dependent RNA helicase DHX33 [EC:5.6.2.6]
       K21356  MFN1; mitofusin 1 [EC:3.6.5.-]
       K06030  MFN2, FZO1; mitofusin 2 [EC:3.6.5.-]
       K02861  RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
       K08847  RIPK3; receptor-interacting serine/threonine-protein kinase 3 [EC:2.7.11.1]
       K17065  DNM1L; dynamin 1-like protein [EC:3.6.5.5]
       K03462  NAMPT; nicotinamide phosphoribosyltransferase [EC:2.4.2.12]
       K21421  NOX2, GP91, CYBB; NADPH oxidase 2 [EC:1.-.-.-]
       K08009  CYBA, P22PHOX; cytochrome b-245, alpha polypeptide
       K20910  TXNIP; thioredoxin-interacting protein
       K03671  TXN, trxA; thioredoxin
       K20876  NEK7; serine/threonine-protein kinase Nek7 [EC:2.7.11.34]
       K11864  BRCC3, BRCC36; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
       K04079  HSP90A, htpG; molecular chaperone HtpG
       K12801  CARD8, CARDINAL; caspase recruitment domain-containing protein 8
       K15838  GPSM3, AGS4; G-protein signaling modulator 3
       K14139  IRGM, LRG47; immunity-related GTPase family M protein [EC:3.6.5.-]
       K12802  PYDC1; pyrin domain-containing protein 1
       K20911  PYDC2, POP2; pyrin domain-containing protein 2
       K12803  MEFV; pyrin
       K12804  PSTPIP1; proline-serine-threonine phosphatase interacting protein 1
       K04398  CASP8; caspase 8 [EC:3.4.22.61]
       K02373  FADD; FAS-associated death domain protein
       K04741  CASP12; caspase 12 [EC:3.4.22.-]
       K12806  CARD16_17_18; caspase recruitment domain-containing protein 16/17/18
       K20863  NLRP6, NALP6; NACHT, LRR and PYD domains-containing protein 6
       K20864  NLRP7, NALP7; NACHT, LRR and PYD domains-containing protein 7
       K08598  yopJ; YopJ protease family
       K20865  NLRP12; NACHT, LRR and PYD domains-containing protein 12
       K02406  fliC, hag; flagellin
       K12807  NAIP, BIRC1; baculoviral IAP repeat-containing protein 1
       K12805  NLRC4, CARD12; NLR family CARD domain-containing protein 4
       K06068  PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
       K20897  GBP2; guanylate-binding protein 2
       K20898  GBP5; guanylate-binding protein 5
       K12966  AIM2; absent in melanoma 2
       K20914  IFI16; gamma-interferon-inducible protein 16
       K20915  TP53BP1, P202; tumor suppressor p53-binding protein 1
       K20916  POP3; pyrin domain-only protein 3
       K04513  RHOA; Ras homolog gene family, member A
       K06071  PKN1; serine/threonine-protein kinase N1 [EC:2.7.11.13]
       K23691  PKN2; serine/threonine-protein kinase N2 [EC:2.7.11.13]
       K06630  YWHAE; 14-3-3 protein epsilon
       K20899  GBP1_3_4_7; guanylate-binding protein 1/3/4/7
       K04395  CASP5; caspase 5 [EC:3.4.22.58]
       K04394  CASP4, CASP11; caspase 4 [EC:3.4.22.57 3.4.22.64]
       K20917  GSDMD; gasdermin-D
       K05130  IFNAR1; interferon receptor 1
       K05131  IFNAR2; interferon receptor 2
       K11217  JAK1; Janus kinase 1 [EC:2.7.10.2]
       K11219  TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
       K11220  STAT1; signal transducer and activator of transcription 1
       K11221  STAT2; signal transducer and activator of transcription 2
       K04693  IRF9, ISGF3G, P48; interferon regulatory factor 9
       K10160  TLR4, CD284; toll-like receptor 4
       K05842  TRIF; toll-like receptor adapter molecule 1
       K04729  MYD88; myeloid differentiation primary response protein MyD88
       K04733  IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
       K12654  STING1, TMEM173, MITA; stimulator of interferon genes protein
     04622 RIG-I-like receptor signaling pathway [PATH:ko04622]
     04623 Cytosolic DNA-sensing pathway [PATH:ko04623]
     04625 C-type lectin receptor signaling pathway [PATH:ko04625]
     04650 Natural killer cell mediated cytotoxicity [PATH:ko04650]
     04612 Antigen processing and presentation [PATH:ko04612]
     04660 T cell receptor signaling pathway [PATH:ko04660]
     04658 Th1 and Th2 cell differentiation [PATH:ko04658]
     04659 Th17 cell differentiation [PATH:ko04659]
     04657 IL-17 signaling pathway [PATH:ko04657]
     04662 B cell receptor signaling pathway [PATH:ko04662]
     04664 Fc epsilon RI signaling pathway [PATH:ko04664]
     04666 Fc gamma R-mediated phagocytosis [PATH:ko04666]
     04670 Leukocyte transendothelial migration [PATH:ko04670]
     04672 Intestinal immune network for IgA production [PATH:ko04672]
     04062 Chemokine signaling pathway [PATH:ko04062]
 
   09152 Endocrine system
 
   09153 Circulatory system
 
   09154 Digestive system
 
   09155 Excretory system
 
   09156 Nervous system
 
   09157 Sensory system
 
   09158 Development and regeneration
 
   09149 Aging
 
   09159 Environmental adaptation
 
 09160 Human Diseases
 
   09161 Cancer: overview
 
   09162 Cancer: specific types
 
   09172 Infectious disease: viral
 
   09171 Infectious disease: bacterial
     05110 Vibrio cholerae infection [PATH:ko05110]
     05120 Epithelial cell signaling in Helicobacter pylori infection [PATH:ko05120]
       K15842  cagA; cytotoxicity-associated immunodominant antigen
       K12086  cag1; cag pathogenicity island protein 1
       K12087  cag2; cag pathogenicity island protein 2
       K12088  cag3; cag pathogenicity island protein 3
       K12089  cag4; cag pathogenicity island protein 4
       K12090  cag5; cag pathogenicity island protein 5
       K03196  virB11, lvhB11; type IV secretion system protein VirB11 [EC:7.4.2.8]
       K12091  cag6; cag pathogenicity island protein 6
       K12092  cag7; cag pathogenicity island protein 7
       K12093  cag8; cag pathogenicity island protein 8
       K12094  cag9; cag pathogenicity island protein 9
       K12095  cag10; cag pathogenicity island protein 10
       K12096  cag11; cag pathogenicity island protein 11
       K12097  cag12; cag pathogenicity island protein 12
       K12098  cag13; cag pathogenicity island protein 13
       K12099  cag14; cag pathogenicity island protein 14
       K12100  cag15; cag pathogenicity island protein 15
       K12101  cag16; cag pathogenicity island protein 16
       K12102  cag17; cag pathogenicity island protein 17
       K12103  cag18; cag pathogenicity island protein 18
       K12104  cag19; cag pathogenicity island protein 19
       K12105  cag20; cag pathogenicity island protein 20
       K12106  cag21; cag pathogenicity island protein 21
       K12107  cag22; cag pathogenicity island protein 22
       K12108  cag23; cag pathogenicity island protein 23 [EC:7.4.2.8]
       K12109  cag24; cag pathogenicity island protein 24
       K12110  cag25; cag pathogenicity island protein 25
       K07293  PTPN11, SHP2; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
       K05099  MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
       K01116  PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
       K05859  PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
       K05701  TJP1, ZO1; tight junction protein 1
       K06089  F11R, JAM1, CD321; junctional adhesion molecule 1
       K06735  JAM2, CD322; junctional adhesion molecule 2
       K06785  JAM3; junctional adhesion molecule 3
       K06786  JAM4, JCAM; junctional adhesion molecule 4
       K06059  ADAM17, TACE, CD156b; disintegrin and metalloproteinase domain-containing protein 17 [EC:3.4.24.86]
       K08523  HBEGF; heparin-binding EGF-like growth factor
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K10030  IL8, CXCL8; interleukin 8
       K04175  CXCR1, IL8RA, CD181; C-X-C chemokine receptor type 1
       K05050  CXCR2, IL8RB, CD182; C-X-C chemokine receptor type 2
       K06704  ADAM10, CD156c; disintegrin and metalloproteinase domain-containing protein 10 [EC:3.4.24.81]
       K05704  SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
       K05854  LYN; tyrosine-protein kinase Lyn [EC:2.7.10.2]
       K05728  CSK; c-src tyrosine kinase [EC:2.7.10.2]
       K04392  RAC1; Ras-related C3 botulinum toxin substrate 1
       K04393  CDC42; cell division control protein 42
       K04441  P38; p38 MAP kinase [EC:2.7.11.24]
       K04409  PAK1; p21-activated kinase 1 [EC:2.7.11.1]
       K04430  MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
       K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
       K04448  JUN; transcription factor AP-1
       K04466  MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
       K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
       K04734  NFKBIA; NF-kappa-B inhibitor alpha
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04735  RELA; transcription factor p65
       K08727  NOD1, CARD4; nucleotide-binding oligomerization domain-containing protein 1
       K05505  CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
       K12499  CCL5; C-C motif chemokine 5
       K11028  vacA; vacuolating cytotoxin
       K08114  PTPRZ; receptor-type tyrosine-protein phosphatase zeta [EC:3.1.3.48]
       K05737  GIT1; G protein-coupled receptor kinase interactor 1
       K02187  CASP3; caspase 3 [EC:3.4.22.56]
       K02145  ATPeV1A, ATP6A; V-type H+-transporting ATPase subunit A [EC:7.1.2.2]
       K02147  ATPeV1B, ATP6B; V-type H+-transporting ATPase subunit B
       K02148  ATPeV1C, ATP6C; V-type H+-transporting ATPase subunit C
       K02149  ATPeV1D, ATP6M; V-type H+-transporting ATPase subunit D
       K02150  ATPeV1E, ATP6E; V-type H+-transporting ATPase subunit E
       K02151  ATPeV1F, ATP6S14; V-type H+-transporting ATPase subunit F
       K02152  ATPeV1G, ATP6G; V-type H+-transporting ATPase subunit G
       K02153  ATPeV0E, ATP6H; V-type H+-transporting ATPase subunit e
       K02154  ATPeV0A, ATP6N; V-type H+-transporting ATPase subunit a
       K02146  ATPeV0D, ATP6D; V-type H+-transporting ATPase subunit d
       K02144  ATPeV1H; V-type H+-transporting ATPase subunit H
       K03662  ATPeVS1, ATP6S1; V-type H+-transporting ATPase S1 subunit
       K02155  ATPeV0C, ATP6L; V-type H+-transporting ATPase 16kDa proteolipid subunit
       K03661  ATPeV0B, ATP6F; V-type H+-transporting ATPase 21kDa proteolipid subunit
       K03191  ureI; acid-activated urea channel
       K14048  ureAB; urease subunit gamma/beta [EC:3.5.1.5]
       K01428  ureC; urease subunit alpha [EC:3.5.1.5]
       K08303  prtC, trhP; U32 family peptidase [EC:3.4.-.-]
       K15843  hopC, alpA; outer membrane protein HopC/AlpA
       K15844  hopB, alpB; outer membrane protein HopB/AlpB
       K15845  hopZ; outer membrane protein HopZ
       K15846  hpaA; neuraminyllactose-binding hemagglutinin
       K15847  babA; outer membrane protein BabA
       K15848  sabA; outer membrane protein SabA
     05130 Pathogenic Escherichia coli infection [PATH:ko05130]
     05132 Salmonella infection [PATH:ko05132]
       K11014  cdtB; cytolethal distending toxin subunit B
       K11023  ptxA, artA, pltA; pertussis toxin subunit 1 [EC:2.4.2.-]
       K19298  subB, artB, pltB; subtilase cytotoxin, subunit B
       K06817  PODXL; podocalyxin-like
       K06478  PTPRC, CD45; receptor-type tyrosine-protein phosphatase C [EC:3.1.3.48]
       K13085  ipgD, sopB; phosphatidylinositol-4,5-bisphosphate 4-phosphatase [EC:3.1.3.78]
       K07887  RAB5A; Ras-related protein Rab-5A
       K07888  RAB5B; Ras-related protein Rab-5B
       K07889  RAB5C; Ras-related protein Rab-5C
       K00914  PIK3C3, VPS34; phosphatidylinositol 3-kinase [EC:2.7.1.137]
       K15347  sifA; secreted effector protein SifA
       K07897  RAB7A; Ras-related protein Rab-7A
       K07898  RAB7B; Ras-related protein Rab-7B
       K23282  PLEKHM1; pleckstrin homology domain-containing family M member 1
       K20179  VPS11, PEP5; vacuolar protein sorting-associated protein 11
       K20180  VPS16; vacuolar protein sorting-associated protein 16
       K20181  VPS18, PEP3; vacuolar protein sorting-associated protein 18
       K20182  VPS33A; vacuolar protein sorting-associated protein 33A
       K20183  VPS39, VAM6; Vam6/Vps39-like protein vacuolar protein sorting-associated protein 39
       K20184  VPS41; vacuolar protein sorting-associated protein 41
       K23936  sopD2; secreted effector protein SopD2
       K13883  RILP; Rab-interacting lysosomal protein
       K10413  DYNC1H; dynein cytoplasmic 1 heavy chain
       K10414  DYNC2H, DNCH2; dynein cytoplasmic 2 heavy chain
       K10415  DYNC1I, DNCI; dynein cytoplasmic 1 intermediate chain
       K10416  DYNC1LI, DNCLI; dynein cytoplasmic 1 light intermediate chain
       K10417  DYNC2LI; dynein cytoplasmic 2 light intermediate chain
       K10418  DYNLL; dynein light chain LC8-type
       K10419  DYNLRB, DNCL2; dynein light chain roadblock-type
       K10420  DYNLT1_3; dynein light chain Tctex-type 1/3
       K04648  DCTN1; dynactin 1
       K10424  DCTN2; dynactin 2
       K10425  DCTN3; dynactin 3
       K10426  DCTN4; dynactin 4
       K10427  DCTN5; dynactin 5
       K10428  DCTN6; dynactin 6
       K16575  ACTR1, ARP1; centractin
       K16576  ACTR10, ARP11; actin-related protein 10
       K07374  TUBA; tubulin alpha
       K07375  TUBB; tubulin beta
       K21954  FYCO1; FYVE and coiled-coil domain-containing protein 1
       K07955  ARL8; ADP-ribosylation factor-like protein 8
       K15348  PLEKHM2, SKIP; pleckstrin homology domain-containing family M member 2
       K10396  KIF5; kinesin family member 5
       K10407  KLC; kinesin light chain
       K15352  pipB2; secreted effector protein PipB2
       K15350  sseF; secreted effector protein SseF
       K15351  sseG; secreted effector protein SseG
       K23935  ACBD3; golgi resident protein GCP60
       K04513  RHOA; Ras homolog gene family, member A
       K15349  sseJ; secreted effector protein SseJ
       K10089  M6PR; cation-dependent mannose-6-phosphate receptor
       K07899  RAB9A, RAB9; Ras-related protein Rab-9A
       K07900  RAB9B; Ras-related protein Rab-9B
       K20282  GCC2; GRIP and coiled-coil domain-containing protein 2
       K23937  STX10; syntaxin 10
       K15353  sspH2; E3 ubiquitin-protein ligase SspH2
       K15354  sseI, srfH; secreted effector protein SseI
       K05759  PFN; profilin
       K04437  FLNA; filamin-A
       K15366  spvB; salmonella plasmid virulence protein B
       K07195  EXOC7, EXO70; exocyst complex component 7
       K19984  EXOC5, SEC10; exocyst complex component 5
       K06111  EXOC4, SEC8; exocyst complex component 4
       K17637  EXOC2, SEC5; exocyst complex component 2
       K07834  RALA; Ras-related protein Ral-A
       K13286  sipC, ipaC, bipC; invasin C
       K13284  sipA, ipaA; invasin A
       K05692  ACTB_G1; actin beta/gamma 1
       K17274  S100A10; protein S100-A10
       K17092  ANXA2; annexin A2
       K23934  AHNAK; neuroblast differentiation-associated protein AHNAK
       K13741  sopE; guanine nucleotide exchange factor SopE
       K13740  sptP; secreted effector protein SptP
       K07864  RHOJ, TCL; Ras homolog gene family, member J
       K13744  ARHGEF26, SGEF; Rho guanine nucleotide exchange factor 26
       K07863  RHOG; Ras homolog gene family, member G
       K12366  ELMO1, CED12; engulfment and cell motility protein 1
       K18985  ELMO2, CED12A; engulfment and cell motility protein 2
       K17388  ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
       K10351  MYL2; myosin regulatory light chain 2
       K12753  MYL5; myosin regulatory light chain 5
       K12754  MYL7; myosin regulatory light chain 7
       K12755  MYL9; myosin regulatory light chain 9
       K12756  MYL10; myosin regulatory light chain 10
       K12757  MYL12; myosin regulatory light chain 12
       K12758  MYLPF; fast skeletal myosin light chain 2
       K23938  FHOD1; FH1/FH2 domain-containing protein 1
       K04393  CDC42; cell division control protein 42
       K04392  RAC1; Ras-related C3 botulinum toxin substrate 1
       K05750  NCKAP1, NAP125; NCK-associated protein 1
       K05749  CYFIP; cytoplasmic FMR1 interacting protein
       K23649  ABI1; abl interactor 1
       K05752  C3ORF10, HSPC300; chromosome 3 open reading frame 10
       K06083  WASF3; WAS protein family, member 3
       K17260  ACTR2, ARP2; actin-related protein 2
       K18584  ACTR3, ARP3; actin-related protein 3
       K05757  ARPC1A_B; actin related protein 2/3 complex, subunit 1A/1B
       K05758  ARPC2; actin related protein 2/3 complex, subunit 2
       K05756  ARPC3; actin related protein 2/3 complex, subunit 3
       K05755  ARPC4; actin related protein 2/3 complex, subunit 4
       K05754  ARPC5; actin related protein 2/3 complex, subunit 5
       K04409  PAK1; p21-activated kinase 1 [EC:2.7.11.1]
       K05733  PAK3, MRX30; p21-activated kinase 3 [EC:2.7.11.1]
       K10358  MYO6; myosin VI
       K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
       K21289  PIK3CG; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma [EC:2.7.1.153]
       K00923  PIK3C2; phosphatidylinositol-4-phosphate 3-kinase [EC:2.7.1.154]
       K18441  CYTH; cytohesin
       K07941  ARF6; ADP-ribosylation factor 6
       K07937  ARF1_2; ADP-ribosylation factor 1/2
       K17923  SNX9_18_33; sorting nexin-9/18/33
       K23612  WASL; neural Wiskott-Aldrich syndrome protein
       K23484  DNM2; dynamin 2 [EC:3.6.5.5]
       K10169  TLR6, CD286; toll-like receptor 6
       K10159  TLR2, CD282; toll-like receptor 2
       K05403  TIRAP; toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
       K04729  MYD88; myeloid differentiation primary response protein MyD88
       K04391  CD14; monocyte differentiation antigen CD14
       K10160  TLR4, CD284; toll-like receptor 4
       K05400  LY96, MD-2; lymphocyte antigen 96
       K02406  fliC, hag; flagellin
       K10168  TLR5; toll-like receptor 5
       K10161  TLR9, CD289; toll-like receptor 9
       K04730  IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
       K04733  IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
       K03175  TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
       K04427  MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
       K04403  MAP3K7IP1, TAB1; TAK1-binding protein 1
       K04404  MAP3K7IP2, TAB2; TAK1-binding protein 2
       K12793  MAP3K7IP3, TAB3; TAK1-binding protein 3
       K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
       K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K04734  NFKBIA; NF-kappa-B inhibitor alpha
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04735  RELA; transcription factor p65
       K08727  NOD1, CARD4; nucleotide-binding oligomerization domain-containing protein 1
       K04079  HSP90A, htpG; molecular chaperone HtpG
       K09487  HSP90B, TRA1; heat shock protein 90kDa beta
       K08846  RIPK2; receptor-interacting serine/threonine-protein kinase 2 [EC:2.7.11.1]
       K18423  CSE1, CAS, XPO2; exportin-2 (importin alpha re-exporter)
       K23940  KPNA1; importin subunit alpha-5
       K23583  KPNA3_4; importin subunit alpha-4/3
       K02985  RP-S3e, RPS3; small subunit ribosomal protein S3e
       K02833  HRAS; GTPase HRas
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04432  MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
       K04433  MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
       K04441  P38; p38 MAP kinase [EC:2.7.11.24]
       K04430  MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
       K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
       K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
       K04379  FOS; proto-oncogene protein c-fos
       K04448  JUN; transcription factor AP-1
       K03156  TNF, TNFA; tumor necrosis factor superfamily, member 2
       K04519  IL1B; interleukin 1 beta
       K05405  IL6; interleukin 6
       K10030  IL8, CXCL8; interleukin 8
       K02105  CTNNB1; catenin beta 1
       K02620  TCF7, TCF-1; transcription factor 7
       K04490  TCF7L1; transcription factor 7-like 1
       K04491  TCF7L2; transcription factor 7-like 2
       K04492  LEF1; lymphoid enhancer-binding factor 1
       K04377  MYC; Myc proto-oncogene protein
       K19557  spvD; salmonella plasmid virulence protein D
       K23941  pipA, gogA, gtgA; PipA/GogA/GtgA family effector protease
       K15343  sspH1; E3 ubiquitin-protein ligase SspH1
       K06071  PKN1; serine/threonine-protein kinase N1 [EC:2.7.11.13]
       K23942  gogB; Gifsy-1 prophage leucine-rich repeat protein
       K10302  FBXO22; F-box protein 22
       K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
       K08598  yopJ; YopJ protease family
       K18015  elaD, sseL; deubiquitinase [EC:3.4.22.-]
       K13450  ospF, mkaD, spvC; phosphothreonine lyase [EC:4.2.3.-]
       K03158  TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
       K03173  TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
       K03171  TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
       K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
       K02861  RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
       K00134  GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
       K04721  TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
       K04722  TNFRSF10A_B, TRAILR1_2, DR4_5, CD261_2; tumor necrosis factor receptor superfamily member 10A/B
       K02373  FADD; FAS-associated death domain protein
       K04398  CASP8; caspase 8 [EC:3.4.22.61]
       K08847  RIPK3; receptor-interacting serine/threonine-protein kinase 3 [EC:2.7.11.1]
       K02159  BAX; apoptosis regulator BAX
       K14021  BAK, BAK1; Bcl-2 homologous antagonist/killer
       K08738  CYC; cytochrome c
       K02161  BCL2; apoptosis regulator Bcl-2
       K02187  CASP3; caspase 3 [EC:3.4.22.56]
       K04397  CASP7; caspase 7 [EC:3.4.22.60]
       K07856  RHOB; Ras homolog gene family, member B
       K07873  RHOH, TTF; Ras homolog gene family, member H
       K07829  RRAS; Ras-related protein R-Ras
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K08849  MLKL; mixed lineage kinase domain-like [EC:2.7.11.1]
       K23943  sseK3; type III secretion system effector arginine glycosyltransferase
       K23944  sseK1; type III secretion system effector arginine glycosyltransferase
       K23945  sseK2; type III secretion system effector
       K23946  slrP; E3 ubiquitin-protein ligase SlrP [EC:2.3.2.27]
       K03671  TXN, trxA; thioredoxin
       K12800  NLRP3, PYPAF1; NACHT, LRR and PYD domains-containing protein 3
       K22487  prgJ; type III secretion system protein
       K03221  yscF, sctF, ssaG, prgI; type III secretion protein F
       K12807  NAIP, BIRC1; baculoviral IAP repeat-containing protein 1
       K12805  NLRC4, CARD12; NLR family CARD domain-containing protein 4
       K12799  PYCARD, ASC; apoptosis-associated speck-like protein containing a CARD
       K01370  CASP1; caspase 1 [EC:3.4.22.36]
       K05482  IL18, IL1F4; interleukin 18
       K04394  CASP4, CASP11; caspase 4 [EC:3.4.22.57 3.4.22.64]
       K04395  CASP5; caspase 5 [EC:3.4.22.58]
       K20917  GSDMD; gasdermin-D
       K13285  sipB, ipaB, bipB; invasin B
     05131 Shigellosis [PATH:ko05131]
       K13285  sipB, ipaB, bipB; invasin B
       K06256  CD44; CD44 antigen
       K13286  sipC, ipaC, bipC; invasin C
       K13287  sipD, ipaD, bipD; invasin D
       K06484  ITGA5, CD49e; integrin alpha 5
       K05719  ITGB1, CD29; integrin beta 1
       K05704  SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
       K05725  PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
       K04438  CRK, CRKII; C-crk adapter molecule crk
       K05726  BCAR1, CAS; breast cancer anti-estrogen resistance 1
       K06106  CTTN, EMS1; cortactin
       K05760  PXN; paxillin
       K12366  ELMO1, CED12; engulfment and cell motility protein 1
       K18985  ELMO2, CED12A; engulfment and cell motility protein 2
       K13708  DOCK1; dedicator of cytokinesis protein 1
       K04392  RAC1; Ras-related C3 botulinum toxin substrate 1
       K05753  WASF1; WAS protein family, member 1
       K05748  WASF2; WAS protein family, member 2
       K17260  ACTR2, ARP2; actin-related protein 2
       K18584  ACTR3, ARP3; actin-related protein 3
       K05757  ARPC1A_B; actin related protein 2/3 complex, subunit 1A/1B
       K05758  ARPC2; actin related protein 2/3 complex, subunit 2
       K05756  ARPC3; actin related protein 2/3 complex, subunit 3
       K05755  ARPC4; actin related protein 2/3 complex, subunit 4
       K05754  ARPC5; actin related protein 2/3 complex, subunit 5
       K05692  ACTB_G1; actin beta/gamma 1
       K04513  RHOA; Ras homolog gene family, member A
       K05740  DIAPH1; diaphanous 1
       K04514  ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
       K17388  ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
       K10351  MYL2; myosin regulatory light chain 2
       K12753  MYL5; myosin regulatory light chain 5
       K12754  MYL7; myosin regulatory light chain 7
       K12755  MYL9; myosin regulatory light chain 9
       K12756  MYL10; myosin regulatory light chain 10
       K12757  MYL12; myosin regulatory light chain 12
       K12758  MYLPF; fast skeletal myosin light chain 2
       K05699  ACTN1_4; actinin alpha 1/4
       K06272  ILK; integrin-linked kinase [EC:2.7.11.1]
       K06271  TLN; talin
       K05700  VCL; vinculin
       K04393  CDC42; cell division control protein 42
       K13284  sipA, ipaA; invasin A
       K13793  ospE, espO; secreted effector OspE
       K13790  icsB, bopA; virulence protein IcsB
       K13743  ipgB2; protein IpgB2
       K13742  ipgB1; protein IpgB1
       K12679  icsA, virG; outer membrane protein IcsA
       K23612  WASL; neural Wiskott-Aldrich syndrome protein
       K05759  PFN; profilin
       K13085  ipgD, sopB; phosphatidylinositol-4,5-bisphosphate 4-phosphatase [EC:3.1.3.78]
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
       K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
       K18441  CYTH; cytohesin
       K07941  ARF6; ADP-ribosylation factor 6
       K07937  ARF1_2; ADP-ribosylation factor 1/2
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K07201  FOXO1; forkhead box protein O1
       K09408  FOXO3; forkhead box protein O3
       K12358  FOXO4; forkhead box protein O4
       K17847  FOXO6; forkhead box protein O6
       K08822  GSK3A; glycogen synthase kinase 3 alpha [EC:2.7.11.26]
       K03083  GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
       K04688  RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
       K06643  MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
       K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
       K05857  PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
       K05860  PLCE; phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
       K01116  PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
       K05859  PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
       K05861  PLCZ; phosphatidylinositol phospholipase C, zeta [EC:3.1.4.11]
       K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
       K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
       K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
       K04281  CAST; calpastatin
       K01367  CAPN1; calpain-1 [EC:3.4.22.52]
       K03853  CAPN2; calpain-2 [EC:3.4.22.53]
       K08583  CAPNS1, CAPN4; calpain, small subunit 1
       K04728  ATM, TEL1; serine-protein kinase ATM [EC:2.7.11.1]
       K04451  TP53, P53; tumor protein p53
       K04570  BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
       K02161  BCL2; apoptosis regulator Bcl-2
       K12785  espG, virA; LEE-encoded effector EspG
       K07345  fimA; major type 1 subunit fimbrin (pilin)
       K00844  HK; hexokinase [EC:2.7.1.1]
       K05862  VDAC1; voltage-dependent anion channel protein 1
       K02159  BAX; apoptosis regulator BAX
       K08738  CYC; cytochrome c
       K15464  BNIP3; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
       K05864  PPID, CYPD; peptidyl-prolyl isomerase D [EC:5.2.1.8]
       K04394  CASP4, CASP11; caspase 4 [EC:3.4.22.57 3.4.22.64]
       K04519  IL1B; interleukin 1 beta
       K05482  IL18, IL1F4; interleukin 18
       K03156  TNF, TNFA; tumor necrosis factor superfamily, member 2
       K03158  TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
       K03171  TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
       K03173  TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
       K09849  TRAF5; TNF receptor-associated factor 5
       K02861  RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
       K04427  MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
       K04403  MAP3K7IP1, TAB1; TAK1-binding protein 1
       K04404  MAP3K7IP2, TAB2; TAK1-binding protein 2
       K12793  MAP3K7IP3, TAB3; TAK1-binding protein 3
       K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
       K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K04734  NFKBIA; NF-kappa-B inhibitor alpha
       K02581  NFKBIB; NF-kappa-B inhibitor beta
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04735  RELA; transcription factor p65
       K10030  IL8, CXCL8; interleukin 8
       K23826  TIFA; TRAF-interacting protein with FHA domain-containing protein A
       K04386  IL1R1, CD121a; interleukin 1 receptor type I
       K04391  CD14; monocyte differentiation antigen CD14
       K10160  TLR4, CD284; toll-like receptor 4
       K02406  fliC, hag; flagellin
       K10168  TLR5; toll-like receptor 5
       K03175  TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
       K06068  PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
       K18050  PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
       K18052  PRKCQ; novel protein kinase C theta type [EC:2.7.11.13]
       K07369  MALT1; mucosa-associated lymphoid tissue lymphoma translocation protein 1 [EC:3.4.22.-]
       K07368  BCL10; B-cell CLL/lymphoma 10
       K08727  NOD1, CARD4; nucleotide-binding oligomerization domain-containing protein 1
       K12791  ARHGEF2, GEF-H1; Rho guanine nucleotide exchange factor 2
       K08846  RIPK2; receptor-interacting serine/threonine-protein kinase 2 [EC:2.7.11.1]
       K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
       K04448  JUN; transcription factor AP-1
       K23827  ospI; glutamine deamidase
       K10704  UBE2V; ubiquitin-conjugating enzyme E2 variant
       K10580  UBE2N, BLU, UBC13; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
       K23828  ipaH1.4_2.5; E3 ubiquitin-protein ligase IpaH1.4/2.5 [EC:2.3.2.27]
       K10630  RBCK1, HOIL1; RanBP-type and C3HC4-type zinc finger-containing protein 1 [EC:2.3.2.31]
       K11974  RNF31, HOIP; E3 ubiquitin-protein ligase RNF31 [EC:2.3.2.31]
       K20894  SHARPIN; shank-associated RH domain-interacting protein
       K23654  nleE, ospZ; T3SS secreted effector NleE
       K23829  TNIP1, ABIN1; TNFAIP3-interacting protein 1
       K13791  ipaH9.8; invasion plasmid antigen
       K13792  ospG; secreted effector OspG
       K06689  UBE2D, UBC4, UBC5; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
       K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
       K03347  CUL1, CDC53; cullin 1
       K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
       K03362  FBXW1_11, BTRC, beta-TRCP; F-box and WD-40 domain protein 1/11
       K23830  ipaH4.5; E3 ubiquitin-protein ligase IpaH4.5 [EC:2.3.2.27]
       K23831  ipaH0722; E3 ubiquitin-protein ligase IpaH0722 [EC:2.3.2.27]
       K17834  CGAS, MB21D1; cyclic GMP-AMP synthase [EC:2.7.7.86]
       K12654  STING1, TMEM173, MITA; stimulator of interferon genes protein
       K04729  MYD88; myeloid differentiation primary response protein MyD88
       K05410  TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
       K05411  IRF3; interferon regulatory factor 3
       K05415  IFNB; interferon beta
       K23832  ipaJ; cysteine protease IpaJ [EC:3.4.22.-]
       K12836  U2AF1; splicing factor U2AF 35 kDa subunit
       K12499  CCL5; C-C motif chemokine 5
       K05427  CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
       K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04441  P38; p38 MAP kinase [EC:2.7.11.24]
       K04445  RPS6KA5, MSK1; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
       K11253  H3; histone H3
       K11586  CBX3, HP1G; chromobox protein 3
       K13450  ospF, mkaD, spvC; phosphothreonine lyase [EC:4.2.3.-]
       K08334  BECN, VPS30, ATG6; beclin
       K17889  ATG14L, ATG14; beclin 1-associated autophagy-related key regulator
       K08333  PIK3R4, VPS15; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]
       K00914  PIK3C3, VPS34; phosphatidylinositol 3-kinase [EC:2.7.1.137]
       K16185  RRAGA_B; Ras-related GTP-binding protein A/B
       K16186  RRAGC_D; Ras-related GTP-binding protein C/D
       K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
       K07204  RAPTOR; regulatory associated protein of mTOR
       K16184  AKT1S1, PRAS40; proline-rich AKT1 substrate 1
       K17890  ATG16L1; autophagy-related protein 16-1
       K08339  ATG5; autophagy-related protein 5
       K08336  ATG12; ubiquitin-like protein ATG12
       K10435  MAP1LC; microtubule-associated protein 1 light chain
       K03990  C3; complement component 3
       K14381  SQSTM1; sequestosome 1
       K21348  CALCOCO2, NDP52; calcium-binding and coiled-coil domain-containing protein 2
       K02927  RP-L40e, RPL40, UBA52; ubiquitin-large subunit ribosomal protein L40e
       K02977  RP-S27Ae, RPS27A, UBA80; ubiquitin-small subunit ribosomal protein S27Ae
       K04551  UBB; ubiquitin B
       K08770  UBC; ubiquitin C
       K16942  SEPT2; septin 2
       K16938  SEPT3_9_12; septin 3/9/12
       K16939  SEPT6_8_11; septin 6/8/11
       K16944  SEPT7, CDC3; septin 7
       K17908  WIPI1_2, ATG18; autophagy-related protein 18
       K17988  TECPR1; tectonin beta-propeller repeat-containing protein 1
       K20121  FNBP1; formin-binding protein 1
       K13520  icsP, sopA; outer membrane protease [EC:3.4.23.-]
       K23833  ospC; secreted effector OspC
       K11006  stxA; shiga toxin subunit A
       K11007  stxB; shiga toxin subunit B
       K11011  set1A; enterotoxin Set1A
       K11012  set1B; enterotoxin Set1B
       K23345  GLMN; glomulin
       K12800  NLRP3, PYPAF1; NACHT, LRR and PYD domains-containing protein 3
       K22487  prgJ; type III secretion system protein
       K12807  NAIP, BIRC1; baculoviral IAP repeat-containing protein 1
       K03221  yscF, sctF, ssaG, prgI; type III secretion protein F
       K12805  NLRC4, CARD12; NLR family CARD domain-containing protein 4
       K12799  PYCARD, ASC; apoptosis-associated speck-like protein containing a CARD
       K01370  CASP1; caspase 1 [EC:3.4.22.36]
       K23834  ipaH7.8; E3 ubiquitin-protein ligase IpaH7.8 [EC:2.3.2.27]
     05135 Yersinia infection [PATH:ko05135]
     05133 Pertussis [PATH:ko05133]
       K12681  prn; pertactin
       K07345  fimA; major type 1 subunit fimbrin (pilin)
       K07347  fimD, fimC, mrkC, htrE, cssD; outer membrane usher protein
       K06484  ITGA5, CD49e; integrin alpha 5
       K05719  ITGB1, CD29; integrin beta 1
       K07326  fhaC; hemolysin activation/secretion protein
       K12688  sphB1, nalP, ausP; autotransporter serine protease [EC:3.4.21.-]
       K15125  fhaB; filamentous hemagglutinin
       K06461  ITGAM, CD11b; integrin alpha M
       K06464  ITGB2, CD18; integrin beta 2
       K11004  hlyB, cyaB; ATP-binding cassette, subfamily B, bacterial HlyB/CyaB
       K11003  hlyD, cyaD; membrane fusion protein, hemolysin D
       K12340  tolC, bepC, cyaE, raxC, sapF, rsaF, hasF; outer membrane protein
       K07389  cyaC, hlyC, rtxC; cytolysin-activating lysine-acyltransferase [EC:2.3.1.-]
       K22944  cyaA; bifunctional hemolysin/adenylate cyclase [EC:4.6.1.1]
       K02183  CALM; calmodulin
       K04513  RHOA; Ras homolog gene family, member A
       K05765  CFL; cofilin
       K02187  CASP3; caspase 3 [EC:3.4.22.56]
       K04397  CASP7; caspase 7 [EC:3.4.22.60]
       K01370  CASP1; caspase 1 [EC:3.4.22.36]
       K12799  PYCARD, ASC; apoptosis-associated speck-like protein containing a CARD
       K12800  NLRP3, PYPAF1; NACHT, LRR and PYD domains-containing protein 3
       K04519  IL1B; interleukin 1 beta
       K12683  brkA; serum resistance protein
       K03986  C1QA; complement C1q subcomponent subunit A
       K03987  C1QB; complement C1q subcomponent subunit B
       K03988  C1QG; complement C1q subcomponent subunit C
       K01330  C1R; complement component 1, r subcomponent [EC:3.4.21.41]
       K01331  C1S; complement component 1, s subcomponent [EC:3.4.21.42]
       K01332  C2; complement component 2 [EC:3.4.21.43]
       K03989  C4; complement component 4
       K03990  C3; complement component 3
       K03994  C5; complement component 5
       K04001  SERPING1, C1INH; C1 inhibitor
       K04002  C4BPA; complement component 4 binding protein alpha
       K04003  C4BPB; complement component 4 binding protein beta
       K12973  pagP, crcA; lipid IVA palmitoyltransferase [EC:2.3.1.251]
       K05400  LY96, MD-2; lymphocyte antigen 96
       K10160  TLR4, CD284; toll-like receptor 4
       K04391  CD14; monocyte differentiation antigen CD14
       K05403  TIRAP; toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
       K04729  MYD88; myeloid differentiation primary response protein MyD88
       K04733  IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
       K04730  IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
       K03175  TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04735  RELA; transcription factor p65
       K05409  TIRP, TRAM; TRIF-related adaptor molecule
       K05842  TRIF; toll-like receptor adapter molecule 1
       K05411  IRF3; interferon regulatory factor 3
       K04441  P38; p38 MAP kinase [EC:2.7.11.24]
       K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
       K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04379  FOS; proto-oncogene protein c-fos
       K04448  JUN; transcription factor AP-1
       K05405  IL6; interleukin 6
       K05406  IL12A; interleukin 12A
       K05425  IL12B; interleukin 12B
       K05426  IL23A; interleukin 23 subunit alpha
       K03156  TNF, TNFA; tumor necrosis factor superfamily, member 2
       K05443  IL10, CSIF; interleukin 10
       K09444  IRF1; interferon regulatory factor 1
       K10155  IRF8; interferon regulatory factor 8
       K10067  SFTPA; pulmonary surfactant-associated protein A
       K11023  ptxA, artA, pltA; pertussis toxin subunit 1 [EC:2.4.2.-]
       K11024  ptxB; pertussis toxin subunit 2
       K11025  ptxC; pertussis toxin subunit 3
       K11026  ptxD; pertussis toxin subunit 4
       K11027  ptxE; pertussis toxin subunit 5
       K04630  GNAI; guanine nucleotide-binding protein G(i) subunit alpha
       K10030  IL8, CXCL8; interleukin 8
       K05506  CXCL5_6, SCYB5_6; C-X-C motif chemokine 5/6
       K08727  NOD1, CARD4; nucleotide-binding oligomerization domain-containing protein 1
       K04383  IL1A; interleukin 1 alpha
       K13241  NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
       K15126  bteA; type III secretion system cytotoxic effector protein
       K07679  evgS, bvgS; two-component system, NarL family, sensor histidine kinase EvgS [EC:2.7.13.3]
       K07690  evgA, bvgA; two-component system, NarL family, response regulator EvgA
     05134 Legionellosis [PATH:ko05134]
     05150 Staphylococcus aureus infection [PATH:ko05150]
     05152 Tuberculosis [PATH:ko05152]
     05100 Bacterial invasion of epithelial cells [PATH:ko05100]
 
   09174 Infectious disease: parasitic
 
   09163 Immune disease
 
   09164 Neurodegenerative disease
 
   09165 Substance dependence
 
   09166 Cardiovascular disease
 
   09167 Endocrine and metabolic disease
 
   09175 Drug resistance: antimicrobial
 
   09176 Drug resistance: antineoplastic
 
 09180 Brite Hierarchies
 
   09181 Protein families: metabolism
 
   09182 Protein families: genetic information processing
 
   09183 Protein families: signaling and cellular processes
     02000 Transporters [BR:ko02000]
     02044 Secretion system [BR:ko02044]
     02042 Bacterial toxins [BR:ko02042]
     02022 Two-component system [BR:ko02022]
     02035 Bacterial motility proteins [BR:ko02035]
     03037 Cilium and associated proteins [BR:ko03037]
     04812 Cytoskeleton proteins [BR:ko04812]
     04147 Exosome [BR:ko04147]
     02048 Prokaryotic defense system [BR:ko02048]
     04030 G protein-coupled receptors [BR:ko04030]
     04050 Cytokine receptors [BR:ko04050]
     04054 Pattern recognition receptors [BR:ko04054]
       K05398  TLR1, CD281; toll-like receptor 1
       K10159  TLR2, CD282; toll-like receptor 2
       K05401  TLR3, CD283; toll-like receptor 3
       K10160  TLR4, CD284; toll-like receptor 4
       K10168  TLR5; toll-like receptor 5
       K10169  TLR6, CD286; toll-like receptor 6
       K05404  TLR7; toll-like receptor 7
       K10170  TLR8, CD288; toll-like receptor 8
       K10161  TLR9, CD289; toll-like receptor 9
       K10171  TLR10, CD290; toll-like receptor 10
       K14142  TLR11; toll-like receptor 11
       K18807  TLR12; toll-like receptor 12
       K18808  TLR13; toll-like receptor 13
       K10069  CLEC1A; C-type lectin domain family 1 member A
       K10070  CLEC1B; C-type lectin domain family 1 member B
       K10071  CLEC2B; C-type lectin domain family 2 member B
       K10072  CLEC2D; C-type lectin domain family 2 member D
       K10057  CLEC4A, CD367; C-type lectin domain family 4 member A
       K06723  CLEC4C, CLECSF11, CLECSF7, CD303; C-type lectin domain family 4 member C
       K10058  CLEC4D, MCL, CD368; C-type lectin domain family 4 member D
       K10059  CLEC4E, MINCLE; C-type lectin domain family 4 member E
       K10061  CLEC4G; C-type lectin superfamily 4 member G
       K06563  CLEC4L_M, DC-SIGN, CD209, CD299; C-type lectin domain family 4 member L/M
       K10073  CLEC5A; C-type lectin domain family 5 member A
       K17514  CLEC6A, DECTIN2; C-type lectin domain family 6 member A
       K10074  CLEC7A, DECTIN1, CD369; C-type lectin domain family 7 member A
       K17515  CLEC9A, CD370; C-type lectin domain family 9 member A
       K06721  CLEC10A, CLECSF13, CLECSF14, CD301; C-type lectin domain family 10 member A
       K17516  CLEC12A, CD371; C-type lectin domain family 12 member A
       K17517  CLEC12B; C-type lectin domain family 12 member B
       K06559  LY75, CD205; lymphocyte antigen 75
       K06560  MRC, CD206, CD280; mannose receptor, C type
       K06561  CD207; CD207 antigen
       K08763  OLR1; oxidised low-density lipoprotein receptor 1
       K08727  NOD1, CARD4; nucleotide-binding oligomerization domain-containing protein 1
       K10165  NOD2, CARD15; nucleotide-binding oligomerization domain-containing protein 2
       K22614  NLRC3, NOD3; NLR family CARD domain-containing protein 3
       K12805  NLRC4, CARD12; NLR family CARD domain-containing protein 4
       K22615  NLRC5, NOD4; NLR family CARD domain containing 5
       K12653  NLRX1; NLR family member X1
       K08060  CIITA; MHC class II transactivator [EC:2.7.11.1]
       K12807  NAIP, BIRC1; baculoviral IAP repeat-containing protein 1
       K12798  NLRP1, CARD7; NACHT, LRR and PYD domains-containing protein 1
       K19409  NLRP2; NACHT, LRR and PYD domains-containing protein 2
       K12800  NLRP3, PYPAF1; NACHT, LRR and PYD domains-containing protein 3
       K22265  NLRP4; NACHT, LRR and PYD domains-containing protein 4
       K22626  NLRP5; NACHT, LRR and PYD domains-containing protein 5
       K20863  NLRP6, NALP6; NACHT, LRR and PYD domains-containing protein 6
       K20864  NLRP7, NALP7; NACHT, LRR and PYD domains-containing protein 7
       K22662  NLRP8, NALP8; NACHT, LRR and PYD domains-containing protein 8
       K22663  NLRP9, NALP9; NACHT, LRR and PYD domains-containing protein 9
       K22266  NLRP10; NACHT, LRR and PYD domains-containing protein 10
       K22664  NLRP11, NALP11; NACHT, LRR and PYD domains-containing protein 11
       K20865  NLRP12; NACHT, LRR and PYD domains-containing protein 12
       K22665  NLRP13, NALP13; NACHT, LRR and PYD domains-containing protein 13
       K22666  NLRP14, NALP14; NACHT, LRR and PYD domains-containing protein 14
       K12646  RIGI, DDX58; ATP-dependent RNA helicase DDX58 [EC:5.6.2.6]
       K12647  IFIH1, MDA5; interferon-induced helicase C domain-containing protein 1 [EC:5.6.2.6]
       K12649  DHX58, LGP2; ATP-dependent RNA helicase DHX58 [EC:5.6.2.6]
     03310 Nuclear receptors [BR:ko03310]
     04040 Ion channels [BR:ko04040]
     04031 GTP-binding proteins [BR:ko04031]
     04052 Cytokines and neuropeptides [BR:ko04052]
     04515 Cell adhesion molecules [BR:ko04515]
     04090 CD molecules [BR:ko04090]
     01504 Antimicrobial resistance genes [BR:ko01504]
     00535 Proteoglycans [BR:ko00535]
     00536 Glycosaminoglycan binding proteins [BR:ko00536]
     00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:ko00537]
     04091 Lectins [BR:ko04091]
     04990 Domain-containing proteins not elsewhere classified [BR:ko04990]
 
   09185 Viral protein families
 
   09184 RNA family
 
 09190 Not Included in Pathway or Brite

[ KO | BRITE | KEGG2 | KEGG ]
Last updated: April 26, 2024