KEGG   ORTHOLOGY: K00914
Entry
K00914                      KO                                     
Symbol
PIK3C3, VPS34
Name
phosphatidylinositol 3-kinase [EC:2.7.1.137]
Pathway
map00562  Inositol phosphate metabolism
map01100  Metabolic pathways
map04070  Phosphatidylinositol signaling system
map04136  Autophagy - other
map04138  Autophagy - yeast
map04140  Autophagy - animal
map04145  Phagosome
map04371  Apelin signaling pathway
map05010  Alzheimer disease
map05014  Amyotrophic lateral sclerosis
map05016  Huntington disease
map05017  Spinocerebellar ataxia
map05022  Pathways of neurodegeneration - multiple diseases
map05131  Shigellosis
map05132  Salmonella infection
map05152  Tuberculosis
map05167  Kaposi sarcoma-associated herpesvirus infection
Reaction
R03362  ATP:1-phosphatidyl-1D-myo-inositol 3-phosphotransferase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    K00914  PIK3C3, VPS34; phosphatidylinositol 3-kinase
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    K00914  PIK3C3, VPS34; phosphatidylinositol 3-kinase
   04070 Phosphatidylinositol signaling system
    K00914  PIK3C3, VPS34; phosphatidylinositol 3-kinase
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    K00914  PIK3C3, VPS34; phosphatidylinositol 3-kinase
   04140 Autophagy - animal
    K00914  PIK3C3, VPS34; phosphatidylinositol 3-kinase
   04138 Autophagy - yeast
    K00914  PIK3C3, VPS34; phosphatidylinositol 3-kinase
   04136 Autophagy - other
    K00914  PIK3C3, VPS34; phosphatidylinositol 3-kinase
 09160 Human Diseases
  09172 Infectious disease: viral
   05167 Kaposi sarcoma-associated herpesvirus infection
    K00914  PIK3C3, VPS34; phosphatidylinositol 3-kinase
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    K00914  PIK3C3, VPS34; phosphatidylinositol 3-kinase
   05131 Shigellosis
    K00914  PIK3C3, VPS34; phosphatidylinositol 3-kinase
   05152 Tuberculosis
    K00914  PIK3C3, VPS34; phosphatidylinositol 3-kinase
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K00914  PIK3C3, VPS34; phosphatidylinositol 3-kinase
   05014 Amyotrophic lateral sclerosis
    K00914  PIK3C3, VPS34; phosphatidylinositol 3-kinase
   05016 Huntington disease
    K00914  PIK3C3, VPS34; phosphatidylinositol 3-kinase
   05017 Spinocerebellar ataxia
    K00914  PIK3C3, VPS34; phosphatidylinositol 3-kinase
   05022 Pathways of neurodegeneration - multiple diseases
    K00914  PIK3C3, VPS34; phosphatidylinositol 3-kinase
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K00914  PIK3C3, VPS34; phosphatidylinositol 3-kinase
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.137  phosphatidylinositol 3-kinase
     K00914  PIK3C3, VPS34; phosphatidylinositol 3-kinase
Membrane trafficking [BR:ko04131]
 Endocytosis
  Macropinocytosis
   Kinases
    K00914  PIK3C3, VPS34; phosphatidylinositol 3-kinase
  Rab GTPases and associated proteins
   Rab associated proteins
    K00914  PIK3C3, VPS34; phosphatidylinositol 3-kinase
 Endosome - Lysosome transport
  Rab GTPases and associated proteins
   Rab associated proteins
    K00914  PIK3C3, VPS34; phosphatidylinositol 3-kinase
 Autophagy
  Autophagosome formation proteins
   PI3K complex
    K00914  PIK3C3, VPS34; phosphatidylinositol 3-kinase
Other DBs
COG: COG5032
GO: 0016303
Genes
HSA: 5289(PIK3C3)
PTR: 455385(PIK3C3)
PPS: 100975178(PIK3C3)
GGO: 101152991(PIK3C3)
PON: 100445919(PIK3C3)
NLE: 100584840(PIK3C3)
HMH: 116468590(PIK3C3)
MCC: 693918(PIK3C3)
MCF: 102136293(PIK3C3)
MTHB: 126941247
MNI: 105499299(PIK3C3)
CSAB: 103222505(PIK3C3)
CATY: 105592559(PIK3C3)
PANU: 101022653(PIK3C3)
TGE: 112611520(PIK3C3)
MLEU: 105528857(PIK3C3)
RRO: 104658709(PIK3C3)
RBB: 108537659(PIK3C3)
TFN: 117063959(PIK3C3)
PTEH: 111539704(PIK3C3)
CANG: 105519272(PIK3C3)
CJC: 100414570(PIK3C3)
SBQ: 101045444(PIK3C3)
CIMI: 108305170(PIK3C3)
CSYR: 103275750(PIK3C3)
MMUR: 105885389(PIK3C3)
LCAT: 123621514(PIK3C3)
PCOQ: 105827070(PIK3C3)
OGA: 100966217(PIK3C3)
MMU: 225326(Pik3c3)
MCAL: 110284734(Pik3c3)
MPAH: 110332837(Pik3c3)
RNO: 65052(Pik3c3)
MCOC: 116086936(Pik3c3)
ANU: 117720071(Pik3c3)
MUN: 110546919(Pik3c3)
CGE: 100765741(Pik3c3)
MAUA: 101833643(Pik3c3)
PROB: 127235104(Pik3c3)
PLEU: 114691662(Pik3c3)
MORG: 121441902 121453313(Pik3c3)
MFOT: 126497180
AAMP: 119815605(Pik3c3)
NGI: 103733619(Pik3c3)
HGL: 101720820(Pik3c3)
CPOC: 100729829(Pik3c3)
CCAN: 109701401(Pik3c3)
DORD: 105984564(Pik3c3)
DSP: 122104335(Pik3c3)
PLOP: 125363831(Pik3c3)
NCAR: 124965428
MMMA: 107139532(Pik3c3)
OCU: 100356448
OPI: 101532025(PIK3C3)
TUP: 102473351(PIK3C3)
GVR: 103603652(PIK3C3)
CFA: 490477(PIK3C3)
CLUD: 112647820(PIK3C3)
VVP: 112918840(PIK3C3)
VLG: 121491613(PIK3C3)
NPO: 129508763(PIK3C3)
AML: 100465351(PIK3C3)
UMR: 103663663(PIK3C3)
UAH: 113253361(PIK3C3)
UAR: 123787345(PIK3C3)
ELK: 111142649
LLV: 125082224
MPUF: 101679553(PIK3C3)
MNP: 132023584(PIK3C3)
MLK: 131811092(PIK3C3)
NVS: 122902914(PIK3C3)
ORO: 101365381(PIK3C3)
EJU: 114205075(PIK3C3)
ZCA: 113912886(PIK3C3)
MLX: 118004647(PIK3C3)
NSU: 110577075(PIK3C3)
LWW: 102740754(PIK3C3)
FCA: 101099249(PIK3C3)
PYU: 121032993(PIK3C3)
PCOO: 112868128(PIK3C3)
PBG: 122470722(PIK3C3)
PVIV: 125149250(PIK3C3)
LRUF: 124517564
PTG: 102971493(PIK3C3)
PPAD: 109276389(PIK3C3)
PUC: 125914658
AJU: 106972936
HHV: 120223553(PIK3C3)
BTA: 534815(PIK3C3)
BOM: 102282920(PIK3C3)
BIU: 109577642(PIK3C3)
BBUB: 102404618(PIK3C3)
BBIS: 104993281(PIK3C3)
CHX: 102171561(PIK3C3)
OAS: 101105709(PIK3C3)
BTAX: 128067387(PIK3C3)
ODA: 120880908(PIK3C3)
CCAD: 122425494(PIK3C3)
MBEZ: 129549677(PIK3C3)
SSC: 503700(PIK3C3)
CFR: 102503733(PIK3C3)
CBAI: 105071659(PIK3C3)
CDK: 105085253(PIK3C3)
VPC: 102538248(PIK3C3)
BACU: 103003736(PIK3C3)
BMUS: 118879949(PIK3C3)
LVE: 103069584(PIK3C3)
OOR: 101273072(PIK3C3)
DLE: 111168878(PIK3C3)
PCAD: 102975170(PIK3C3)
PSIU: 116738765(PIK3C3)
NASI: 112410059(PIK3C3)
ECB: 100053039(PIK3C3)
EPZ: 103543294
EAI: 106836928(PIK3C3)
MYB: 102257257(PIK3C3)
MYD: 102773363(PIK3C3)
MMYO: 118662908(PIK3C3)
MLF: 102439076(PIK3C3)
PKL: 118707790(PIK3C3)
EFUS: 103303864(PIK3C3)
MNA: 107546605(PIK3C3)
DRO: 112322978(PIK3C3)
SHON: 118978222(PIK3C3)
AJM: 119040502(PIK3C3)
PDIC: 114506610(PIK3C3)
PHAS: 123826380(PIK3C3)
MMF: 118618488(PIK3C3)
PPAM: 129078690(PIK3C3)
HAI: 109380396(PIK3C3)
RFQ: 117011900(PIK3C3)
PALE: 102897610(PIK3C3)
PGIG: 120586191(PIK3C3)
PVP: 105292883(PIK3C3)
RAY: 107500133(PIK3C3)
MJV: 108396919(PIK3C3)
TOD: 119243088(PIK3C3)
SARA: 101554294(PIK3C3)
LAV: 100675552(PIK3C3)
TMU: 101345298
ETF: 101644561(PIK3C3)
DNM: 101421948(PIK3C3)
MDO: 100011397(PIK3C3)
GAS: 123252319(PIK3C3)
SHR: 100924620(PIK3C3)
AFZ: 127543550
PCW: 110207949(PIK3C3)
OAA: 100076306(PIK3C3)
GGA: 100857877(PIK3C3)
PCOC: 116237705(PIK3C3)
MGP: 100547298(PIK3C3)
CJO: 107305728(PIK3C3)
TPAI: 128074624(PIK3C3)
LMUT: 125687152(PIK3C3)
NMEL: 110389713(PIK3C3)
APLA: 101791899(PIK3C3)
ACYG: 106037333(PIK3C3)
CATA: 118254580(PIK3C3)
AFUL: 116500639(PIK3C3)
TGU: 100221298(PIK3C3)
LSR: 110475063(PIK3C3)
SCAN: 103820653(PIK3C3)
PMOA: 120497697(PIK3C3)
OTC: 121345286(PIK3C3)
PRUF: 121365797(PIK3C3)
GFR: 102038172(PIK3C3)
FAB: 101819120(PIK3C3)
OMA: 130264983(PIK3C3)
PHI: 102104229(PIK3C3)
PMAJ: 107216245(PIK3C3)
CCAE: 111940974(PIK3C3)
CCW: 104694819(PIK3C3)
CBRC: 103623846(PIK3C3)
ETL: 114058250(PIK3C3)
ZAB: 102065714(PIK3C3)
ZLE: 135459461(PIK3C3)
ACHL: 103801537(PIK3C3)
SVG: 106865028(PIK3C3)
MMEA: 130584511(PIK3C3)
HRT: 120765437(PIK3C3)
FPG: 101923473(PIK3C3)
FCH: 102050375(PIK3C3)
CLV: 102083533(PIK3C3)
EGZ: 104134209(PIK3C3)
PCRI: 104024398(PIK3C3)
PLET: 104626833(PIK3C3)
PCAO: 104044619(PIK3C3)
ACUN: 113489677(PIK3C3)
TALA: 104368360(PIK3C3)
PADL: 103923250(PIK3C3)
AFOR: 103900486(PIK3C3)
ACHC: 115336743(PIK3C3)
HALD: 104310919(PIK3C3)
HLE: 104830887(PIK3C3)
AGEN: 126035982
GCL: 127027462
CSTI: 104554577(PIK3C3)
MUI: 104543268(PIK3C3)
BREG: 104637959(PIK3C3)
FGA: 104069567(PIK3C3)
GSTE: 104250711
LDI: 104345116(PIK3C3)
MNB: 103771024(PIK3C3)
OHA: 104335628(PIK3C3)
NNT: 104399438(PIK3C3)
SHAB: 115619678(PIK3C3)
DPUB: 104301021(PIK3C3)
PGUU: 104465760(PIK3C3)
ACAR: 104531728(PIK3C3)
CPEA: 104395351(PIK3C3)
AVIT: 104274277(PIK3C3)
CVF: 104292260(PIK3C3)
RTD: 128902211(PIK3C3)
CUCA: 104067509(PIK3C3)
BRHI: 104490099(PIK3C3)
AAM: 106489354(PIK3C3)
AROW: 112977860(PIK3C3)
NPD: 112947417(PIK3C3)
TGT: 104578209(PIK3C3)
DNE: 112985111(PIK3C3)
SCAM: 104138510(PIK3C3)
ASN: 102374393(PIK3C3)
AMJ: 102577320(PIK3C3)
CPOO: 109307759(PIK3C3)
GGN: 109297987(PIK3C3)
PSS: 102445385(PIK3C3)
CMY: 102940165(PIK3C3)
CCAY: 125636608(PIK3C3)
DCC: 119855595(PIK3C3)
CPIC: 101944037(PIK3C3)
TST: 117878889(PIK3C3)
CABI: 116819754(PIK3C3)
MRV: 120408432(PIK3C3)
ACS: 100552043(pik3c3)
ASAO: 132766840(PIK3C3)
PVT: 110091014(PIK3C3)
SUND: 121922946(PIK3C3)
PBI: 103052307(PIK3C3)
PMUR: 107298510(PIK3C3)
CTIG: 120316657(PIK3C3)
TSR: 106542713(PIK3C3) 106554370
APRI: 131192356(PIK3C3)
PTEX: 113444941(PIK3C3)
NSS: 113424204(PIK3C3)
VKO: 123024002(PIK3C3)
PMUA: 114606411(PIK3C3)
PRAF: 128423189(PIK3C3)
ZVI: 118077111(PIK3C3)
HCG: 128347410(PIK3C3)
STOW: 125436809(PIK3C3)
EMC: 129335074(PIK3C3)
XLA: 108705528(pik3c3.S) 446671(pik3c3.L)
XTR: 100485933(pik3c3)
NPR: 108804436(PIK3C3)
RTEM: 120926316(PIK3C3)
BBUF: 120992284(PIK3C3)
BGAR: 122924826(PIK3C3)
MUO: 115462842(PIK3C3)
GSH: 117356052(PIK3C3)
DRE: 548346(pik3c3)
PTET: 122349533(pik3c3)
LROH: 127168571(pik3c3)
OMC: 131544716(pik3c3)
PPRM: 120469838(pik3c3)
RKG: 130102602(pik3c3)
MAMB: 125264545(pik3c3)
CIDE: 127516090
TROS: 130557740(pik3c3)
TDW: 130417814(pik3c3)
MANU: 129440553(pik3c3)
IPU: 108267968
IFU: 128610292(pik3c3)
PHYP: 113540313(pik3c3)
SMEO: 124387011(pik3c3)
TFD: 113663109(pik3c3)
TVC: 132848879(pik3c3)
TRN: 134312413(pik3c3)
AMEX: 103034827(pik3c3)
CMAO: 118825529(pik3c3)
EEE: 113578319(pik3c3)
CHAR: 105904572(pik3c3)
TRU: 101073179(pik3c3)
TFS: 130523156(pik3c3)
LCO: 104932921(pik3c3)
NCC: 104958187(pik3c3)
TBEN: 117498013(pik3c3)
CGOB: 115023619(pik3c3)
PGEO: 117463756(pik3c3)
GACU: 117539199(pik3c3)
EMAC: 134872804(pik3c3)
ELY: 117246404(pik3c3)
EFO: 125883917(pik3c3)
PLEP: 121962456(pik3c3)
SLUC: 116043323(pik3c3)
ECRA: 117962161(pik3c3)
ESP: 116706994(pik3c3)
PFLV: 114545922(pik3c3)
GAT: 120822141(pik3c3)
PPUG: 119223355(pik3c3)
AFB: 129093535(pik3c3)
CLUM: 117747790(pik3c3)
PSWI: 130211865(pik3c3)
MSAM: 119911758(pik3c3)
SCHU: 122870475(pik3c3)
CUD: 121504902(pik3c3)
ALAT: 119027462(pik3c3)
MZE: 101485817(pik3c3)
ONL: 100693616(pik3c3)
OAU: 116333579(pik3c3)
OLA: 101175027(pik3c3)
OML: 112155756(pik3c3)
CSAI: 133420304(pik3c3)
XMA: 102231703(pik3c3)
XCO: 114157271(pik3c3)
XHE: 116733006(pik3c3)
PRET: 103475962(pik3c3)
PFOR: 103145960
PLAI: 106944723(pik3c3)
PMEI: 106932178(pik3c3)
GAF: 122820367(pik3c3)
PPRL: 129379438(pik3c3)
CVG: 107085215(pik3c3)
CTUL: 119773366(pik3c3)
GMU: 124881257(pik3c3)
NFU: 107377258(pik3c3)
KMR: 108245939(pik3c3)
ALIM: 106529974(pik3c3)
NWH: 119415995(pik3c3)
AOCE: 111580203(pik3c3)
MCEP: 124997841(pik3c3)
CSEM: 103388478(pik3c3)
POV: 109634829(pik3c3)
SSEN: 122761944(pik3c3)
HHIP: 117752210(pik3c3)
HSP: 118102367(pik3c3)
PPLT: 128430114(pik3c3)
SMAU: 118320647(pik3c3)
LCF: 108903074
SDU: 111235652(pik3c3)
SLAL: 111647201(pik3c3)
XGL: 120797631(pik3c3)
HCQ: 109508399(pik3c3)
SSCV: 125983698
SBIA: 133494632(pik3c3)
PEE: 133398056(pik3c3)
PTAO: 133472477(pik3c3)
BPEC: 110171971(pik3c3)
MALB: 109971461(pik3c3)
BSPL: 114842811(pik3c3)
SJO: 128383697(pik3c3)
OTW: 112214613
OMY: 110500468
OGO: 124014089(pik3c3)
ONE: 115133421(pik3c3)
OKI: 109896951(pik3c3)
OKE: 118392109(pik3c3)
SALP: 111953006(pik3c3) 112073198
CCLU: 121572210(pik3c3)
ELS: 105020543(pik3c3)
SFM: 108932928(pik3c3)
PKI: 111851000(pik3c3)
AANG: 118232028(pik3c3)
LOC: 102689720(pik3c3)
PSPA: 121294688(pik3c3)
ARUT: 117409615(pik3c3)
PSEX: 120528026(pik3c3)
LCM: 102353717(PIK3C3)
CMK: 103181014(pik3c3)
RTP: 109918745(pik3c3) 109924008
CPLA: 122548121(pik3c3)
HOC: 132818709(pik3c3)
LERI: 129695860(pik3c3)
PMRN: 116953600(PIK3C3)
LRJ: 133355123(PIK3C3)
BFO: 118409779
BBEL: 109463078
CIN: 100182163
SCLV: 120339466
SPU: 591736
LPIC: 129262225
APLC: 110987621
AJC: 117101202
DME: Dmel_CG5373(Pi3K59F)
DER: 6547886
DSE: 6615739
DSI: Dsimw501_GD11777(Dsim_GD11777)
DAN: 6495908
DSR: 110181124
DPO: 4804547
DPE: 6592426
DMN: 108158712
DWI: 6652137
DGR: 6560703
DAZ: 108617191
DNV: 108654132
DHE: 111603830
DVI: 6626079
CCAT: 101461414
BOD: 106620790
BDR: 105227287
AOQ: 129243680
TDA: 119685263
MDE: 101893911
SCAC: 106086648
LCQ: 111677355
LSQ: 119603971
GFS: 119636667
ECOE: 129951324
HIS: 119659793
AGA: 1279696
ACOZ: 120958024
AARA: 120903269
ASTE: 118510969
AFUN: 125761866
AMOU: 128300422
AALI: 118461484
AAG: 23687538
AALB: 109406736
ASUA: 134227209
CPII: 120426680
CNS: 116349110
BCOO: 119074570
AME: 725770
ACER: 108001460
ALAB: 122719141
ADR: 102673273
AFLR: 100871103
BIM: 100743734
BBIF: 117214699
BVK: 117233233
BVAN: 117166625
BTER: 100642247
BAFF: 126915801
BPYO: 122568120
BPAS: 132915638
FVI: 122527475
CCAL: 108632581
OLG: 117611572
MGEN: 117219007
NMEA: 116428705
CGIG: 122403474
SOC: 105207657
MPHA: 105829108
AEC: 105150362
ACEP: 105624623
PBAR: 105432669
VEM: 105562848
HST: 105184260
DQU: 106745184
CFO: 105258094
LHU: 105678308
PGC: 109858806
OBO: 105288170
PCF: 106790430
PFUC: 122519039
VPS: 122632507
VCRB: 124427722
VVE: 124950820
NVI: 100119508
CSOL: 105366147
TPRE: 106654946
LHT: 122500516
LBD: 127290906
MDL: 103579842
CGLO: 123266728
FAS: 105271590
DAM: 107041811
CINS: 118073066
VCAN: 122412517
CCIN: 107265624
DSM: 124413139
NPT: 124221883
NFB: 124185038
NLO: 107222989
NVG: 124307937
AROA: 105693491
TCA: 656409
DPA: 109546210
SOY: 115881983
AGRG: 126734032
ATD: 109603468
CSET: 123318617
AGB: 108917233
LDC: 111503270
DVV: 114326907
NVL: 108569716
APLN: 108737618
PPYR: 116163678
OTU: 111419187
BMOR: 101743450
MSEX: 115444773
BANY: 112049315
MJU: 123874285
NIQ: 126773204
VCD: 124534596
MCIX: 123658950
PMAC: 106714642
PPOT: 106106456
PXU: 106122537
PRAP: 111001008
PBX: 123707796
PNAP: 125050637
ZCE: 119839174
CCRC: 123698763
LSIN: 126965278
AAGE: 121734350
HAW: 110379084
HZE: 124637096
TNL: 113493781
SLIU: 111354938
OFU: 114349705
ATRA: 106129706
PXY: 105394691
PGW: 126370848
LGLY: 125233886
CFEL: 113364177
CCRN: 123301709
API: 100166620
DNX: 107168045
AGS: 114123453
RMD: 113551622
ACOO: 126842656
DVT: 126902388
BTAB: 109044022
DCI: 103520158
CLEC: 106670969
MQU: 129002745
FOC: 113210507
TPAL: 117645070
ZNE: 110837047
CSEC: 111871322
SGRE: 126282110
BROR: 134536656
IEL: 124167369
FCD: 110849945
DMK: 116925546
DPZ: 124320816
PVM: 113808559
PJA: 122266841
PMOO: 119594956
HAME: 121876643
PCLA: 123766227
CQD: 128684589
PTRU: 123513025
ESN: 127010286
MNZ: 135216713
HAZT: 108665875
ISC: 8034579
DSV: 119442639
RSAN: 119387440
RMP: 119188305
VDE: 111254625
VJA: 111260050
TUT: 107364881
DPTE: 113789441
DFR: 124497801
CSCU: 111636620
PTEP: 107450591
ABRU: 129961772
UDV: 129223770
SDM: 118187720
LPOL: 106468292
PMEO: 129591551
CEL: CELE_B0025.1(vps-34)
CBR: CBG_22101(Cbr-vps-34)
BMY: BM_BM1685(Bma-vps-34)
TSP: Tsp_00889
PVUL: 126817871
PCAN: 112553563
BGT: 106079911
GAE: 121382717
HRF: 124136691
HRJ: 124255409
CRG: 105334736
CANU: 128179023
OED: 125650440
MYI: 110455003
PMAX: 117335207
MCAF: 127734602
MMER: 128558998
RPHI: 132729727
DPOL: 127877639
OBI: 106868964
OSN: 115220770
LJP: 135472375
LAK: 106169742
SHX: MS3_00006188(PIK3C3_1)
EGL: EGR_03783
LLON: 135482730
NVE: 5517667
ATEN: 116307928
ADF: 107334220
AMIL: 114964824
PDAM: 113683608
SPIS: 111322905
DGT: 114529311
XEN: 124447123
HMG: 100215627
ATH: AT1G60490(VPS34)
ALY: 9322680
CRB: 17894041
BRP: 103838506
BOE: 106319020
CPAP: 110813127
CIT: 102620738
PVY: 116135461
TCC: 18609484
GRA: 105785783
GAB: 108467210
VRA: 106777832
VAR: 108335910
VUN: 114173583
VUM: 124837293
CCAJ: 109798596
APRC: 113853303
MTR: 11415599
TPRA: 123908625
CAM: 101495936
PSAT: 127119307
VVO: 131650741
LJA: Lj2g3v1414920.1(Lj2g3v1414920.1)
ADU: 107488788
AIP: 107643351
PCIN: 129311244
FVE: 101306129
RCN: 112196284
PPER: 18789049
PMUM: 103321780
PAVI: 110753252
PDUL: 117616780
ZJU: 107428711
MNT: 21410365
CSAV: 115713047
CSV: 101210847
CMO: 103487692
BHJ: 120076497
MCHA: 111004800
CMAX: 111491915
CMOS: 111462695
CPEP: 111804694
RCU: 8282588
JCU: 105644608
HBR: 110641632
MESC: 110628260
POP: 7484773
PEU: 105138301
PALZ: 118044576
JRE: 108986778
CILL: 122313246
CAVE: 132177669
QSU: 112033997
QLO: 115982555
VVI: 100263708
VRI: 117915042
SLY: 101250591
SPEN: 107018245
SOT: 102588478
SSTN: 125854906
SDUL: 129870190
CANN: 107870091
LBB: 132613742
NTA: 107788462 107795370(PI3K)
NSY: 104247926
NTO: 104099989
NAU: 109211788
INI: 109172080
ITR: 116024675
SIND: 105178723
EGT: 105951933
SMIL: 130985568
APAN: 127266013
ECAD: 122579052
LSV: 111906428
CCAV: 112527528
DCR: 108223227
CSIN: 114299222
RVL: 131310930
AEW: 130779462
BVG: 104897374
SOE: 110782962
ATRI: 130807527
MOF: 131145011
NNU: 104606043
MING: 122077036
TSS: 122654397
OBR: 102711258
ATS: 109774764
TUA: 125507877
LPER: 127317966
LRD: 124685151
SBI: 110436820
ZMA: 103653397
SITA: 101768837
SVS: 117860576
PHAI: 112896755
MUS: 103991980
DCT: 110096521
PEQ: 110019674
AOF: 109844443
MSIN: 131235510
NCOL: 116248157
ATR: 18438846
PPP: 112288042
APRO: F751_4646
MPP: MICPUCDRAFT_42284(JGI:MicpuC2_42284)
SCE: YLR240W(VPS34)
SEUB: DI49_3750
ERC: Ecym_4166
KMX: KLMA_50575(VPS34)
NCS: NCAS_0C02830(NCAS0C02830)
NDI: NDAI_0G02160(NDAI0G02160)
TPF: TPHA_0C02310(TPHA0C02310)
TBL: TBLA_0H00850(TBLA0H00850)
TDL: TDEL_0F05250(TDEL0F05250)
KAF: KAFR_0H01890(KAFR0H01890)
KNG: KNAG_0A02620(KNAG0A02620)
PIC: PICST_42745(VPS34)
LEL: PVL30_000588(VPS34)
CAL: CAALFM_C106680WA(VPS34)
SLB: AWJ20_4460(VPS34)
NCR: NCU00656
NTE: NEUTE1DRAFT133965(NEUTE1DRAFT_133965)
SMP: SMAC_01337(putative_mec1/tel1)
PBEL: QC761_120030(VPS34)
PPSD: QC762_120030(VPS34)
PPSP: QC763_120030(VPS34)
PPSA: QC764_120030(VPS34)
MGR: MGG_03069
PGRI: PgNI_10276
SSCK: SPSK_05906
MAW: MAC_00820
MAJ: MAA_07417
CMT: CCM_03362
PTKZ: JDV02_009892(VPS34)
MBE: MBM_07534
ALUC: AKAW2_11732S(VPS34)
ACHE: ACHE_50569S(VPS34)
APUU: APUU_71004A(VPS34)
ABE: ARB_06637
TVE: TRV_02431
PTE: PTT_16627
SPO: SPAC458.05(pik3)
SOM: SOMG_03860(pik3)
CNE: CNB03120
CNB: CNBB2580
CDEU: CNBG_9144
CCAC: CcaHIS019_0705410(VPS34)
ABP: AGABI1DRAFT75039(AGABI1DRAFT_75039)
ABV: AGABI2DRAFT218336(AGABI2DRAFT_218336)
SCM: SCHCO_02625566(SCHCODRAFT_02625566)
SLA: SERLADRAFT_369876(Vsp34)
WSE: WALSEDRAFT_56006(Vps34p)
MGL: MGL_1161
MRT: MRET_2991
DDI: DDB_G0289601(pikE)
DFA: DFA_11912(pikE)
EHI: EHI_096560(6.t00051)
PREL: PRELSG_1016600(PI3K)
CPV: cgd6_1760
EHX: EMIHUDRAFT_631972(VPS34-2)
 » show all
Reference
PMID:7628435
  Authors
Volinia S, Dhand R, Vanhaesebroeck B, MacDougall LK, Stein R, Zvelebil MJ, Domin J, Panaretou C, Waterfield MD
  Title
A human phosphatidylinositol 3-kinase complex related to the yeast Vps34p-Vps15p protein sorting system.
  Journal
EMBO J 14:3339-48 (1995)
DOI:10.1002/j.1460-2075.1995.tb07340.x
  Sequence
[hsa:5289]
LinkDB

KEGG   ORTHOLOGY: K02649
Entry
K02649                      KO                                     
Symbol
PIK3R1_2_3
Name
phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
Pathway
map01521  EGFR tyrosine kinase inhibitor resistance
map01522  Endocrine resistance
map01524  Platinum drug resistance
map04012  ErbB signaling pathway
map04014  Ras signaling pathway
map04015  Rap1 signaling pathway
map04024  cAMP signaling pathway
map04062  Chemokine signaling pathway
map04066  HIF-1 signaling pathway
map04068  FoxO signaling pathway
map04070  Phosphatidylinositol signaling system
map04071  Sphingolipid signaling pathway
map04072  Phospholipase D signaling pathway
map04140  Autophagy - animal
map04150  mTOR signaling pathway
map04151  PI3K-Akt signaling pathway
map04152  AMPK signaling pathway
map04210  Apoptosis
map04211  Longevity regulating pathway
map04213  Longevity regulating pathway - multiple species
map04218  Cellular senescence
map04360  Axon guidance
map04370  VEGF signaling pathway
map04380  Osteoclast differentiation
map04510  Focal adhesion
map04550  Signaling pathways regulating pluripotency of stem cells
map04611  Platelet activation
map04613  Neutrophil extracellular trap formation
map04620  Toll-like receptor signaling pathway
map04625  C-type lectin receptor signaling pathway
map04630  JAK-STAT signaling pathway
map04650  Natural killer cell mediated cytotoxicity
map04660  T cell receptor signaling pathway
map04662  B cell receptor signaling pathway
map04664  Fc epsilon RI signaling pathway
map04666  Fc gamma R-mediated phagocytosis
map04668  TNF signaling pathway
map04670  Leukocyte transendothelial migration
map04722  Neurotrophin signaling pathway
map04725  Cholinergic synapse
map04750  Inflammatory mediator regulation of TRP channels
map04810  Regulation of actin cytoskeleton
map04910  Insulin signaling pathway
map04914  Progesterone-mediated oocyte maturation
map04915  Estrogen signaling pathway
map04917  Prolactin signaling pathway
map04919  Thyroid hormone signaling pathway
map04923  Regulation of lipolysis in adipocytes
map04926  Relaxin signaling pathway
map04929  GnRH secretion
map04930  Type II diabetes mellitus
map04931  Insulin resistance
map04932  Non-alcoholic fatty liver disease
map04933  AGE-RAGE signaling pathway in diabetic complications
map04935  Growth hormone synthesis, secretion and action
map04960  Aldosterone-regulated sodium reabsorption
map04973  Carbohydrate digestion and absorption
map05010  Alzheimer disease
map05017  Spinocerebellar ataxia
map05020  Prion disease
map05100  Bacterial invasion of epithelial cells
map05131  Shigellosis
map05135  Yersinia infection
map05142  Chagas disease
map05146  Amoebiasis
map05160  Hepatitis C
map05161  Hepatitis B
map05162  Measles
map05163  Human cytomegalovirus infection
map05164  Influenza A
map05165  Human papillomavirus infection
map05166  Human T-cell leukemia virus 1 infection
map05167  Kaposi sarcoma-associated herpesvirus infection
map05168  Herpes simplex virus 1 infection
map05169  Epstein-Barr virus infection
map05170  Human immunodeficiency virus 1 infection
map05171  Coronavirus disease - COVID-19
map05200  Pathways in cancer
map05203  Viral carcinogenesis
map05205  Proteoglycans in cancer
map05206  MicroRNAs in cancer
map05207  Chemical carcinogenesis - receptor activation
map05208  Chemical carcinogenesis - reactive oxygen species
map05210  Colorectal cancer
map05211  Renal cell carcinoma
map05212  Pancreatic cancer
map05213  Endometrial cancer
map05214  Glioma
map05215  Prostate cancer
map05218  Melanoma
map05220  Chronic myeloid leukemia
map05221  Acute myeloid leukemia
map05222  Small cell lung cancer
map05223  Non-small cell lung cancer
map05224  Breast cancer
map05225  Hepatocellular carcinoma
map05226  Gastric cancer
map05230  Central carbon metabolism in cancer
map05231  Choline metabolism in cancer
map05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
map05415  Diabetic cardiomyopathy
map05417  Lipid and atherosclerosis
map05418  Fluid shear stress and atherosclerosis
Reaction
R03362  ATP:1-phosphatidyl-1D-myo-inositol 3-phosphotransferase
R04545  ATP:1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate 3-phosphotransferase
R05795  ATP:1-phosphatidyl-1D-myo-inositol-4-phosphate 3-phosphotransferase
Disease
H00085  Agammaglobulinemias
H01370  SHORT syndrome
H01387  Activated PI3K-delta syndrome
H01885  Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04014 Ras signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04015 Rap1 signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04370 VEGF signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04630 JAK-STAT signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04668 TNF signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04066 HIF-1 signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04068 FoxO signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04070 Phosphatidylinositol signaling system
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04072 Phospholipase D signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04071 Sphingolipid signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04024 cAMP signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04151 PI3K-Akt signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04152 AMPK signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04150 mTOR signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
  09143 Cell growth and death
   04210 Apoptosis
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04218 Cellular senescence
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04550 Signaling pathways regulating pluripotency of stem cells
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04613 Neutrophil extracellular trap formation
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04620 Toll-like receptor signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04625 C-type lectin receptor signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04650 Natural killer cell mediated cytotoxicity
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04660 T cell receptor signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04662 B cell receptor signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04664 Fc epsilon RI signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04666 Fc gamma R-mediated phagocytosis
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04670 Leukocyte transendothelial migration
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04062 Chemokine signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
  09152 Endocrine system
   04910 Insulin signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04923 Regulation of lipolysis in adipocytes
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04929 GnRH secretion
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04915 Estrogen signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04914 Progesterone-mediated oocyte maturation
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04917 Prolactin signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04926 Relaxin signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04935 Growth hormone synthesis, secretion and action
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04919 Thyroid hormone signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
  09156 Nervous system
   04725 Cholinergic synapse
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04722 Neurotrophin signaling pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
  09158 Development and regeneration
   04360 Axon guidance
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04380 Osteoclast differentiation
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
  09149 Aging
   04211 Longevity regulating pathway
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04213 Longevity regulating pathway - multiple species
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05206 MicroRNAs in cancer
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05205 Proteoglycans in cancer
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05207 Chemical carcinogenesis - receptor activation
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05208 Chemical carcinogenesis - reactive oxygen species
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05203 Viral carcinogenesis
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05230 Central carbon metabolism in cancer
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05231 Choline metabolism in cancer
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
  09162 Cancer: specific types
   05210 Colorectal cancer
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05212 Pancreatic cancer
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05225 Hepatocellular carcinoma
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05226 Gastric cancer
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05214 Glioma
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05221 Acute myeloid leukemia
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05220 Chronic myeloid leukemia
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05218 Melanoma
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05211 Renal cell carcinoma
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05215 Prostate cancer
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05213 Endometrial cancer
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05224 Breast cancer
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05222 Small cell lung cancer
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05223 Non-small cell lung cancer
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05170 Human immunodeficiency virus 1 infection
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05161 Hepatitis B
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05160 Hepatitis C
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05171 Coronavirus disease - COVID-19
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05164 Influenza A
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05162 Measles
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05168 Herpes simplex virus 1 infection
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05163 Human cytomegalovirus infection
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05167 Kaposi sarcoma-associated herpesvirus infection
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05169 Epstein-Barr virus infection
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05165 Human papillomavirus infection
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
  09171 Infectious disease: bacterial
   05131 Shigellosis
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05135 Yersinia infection
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05100 Bacterial invasion of epithelial cells
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05142 Chagas disease
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05017 Spinocerebellar ataxia
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05020 Prion disease
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05418 Fluid shear stress and atherosclerosis
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   05415 Diabetic cardiomyopathy
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04932 Non-alcoholic fatty liver disease
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04931 Insulin resistance
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   04933 AGE-RAGE signaling pathway in diabetic complications
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   01524 Platinum drug resistance
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
   01522 Endocrine resistance
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
Membrane trafficking [BR:ko04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
Genes
HSA: 5295(PIK3R1) 5296(PIK3R2) 8503(PIK3R3)
PTR: 455855(PIK3R2) 456565(PIK3R3) 461836(PIK3R1)
PPS: 100969981(PIK3R2) 100986080(PIK3R3) 100994315(PIK3R1)
GGO: 101129336(PIK3R3) 101130978(PIK3R1) 101135298(PIK3R2)
PON: 100173589(PIK3R1) 100174298(PIK3R3) 100437617(PIK3R2)
NLE: 100591270(PIK3R3) 100599301(PIK3R2) 100605788(PIK3R1)
HMH: 116462749(PIK3R1) 116473104(PIK3R3) 116478691(PIK3R2)
MCC: 698996(PIK3R1) 707310(PIK3R3) 719367(PIK3R2)
MCF: 101866246(PIK3R1) 102124804(PIK3R2) 102137291(PIK3R3)
MTHB: 126942202 126956531 126961422
MNI: 105475205(PIK3R1) 105488082(PIK3R2) 105494953(PIK3R3)
CSAB: 103222594(PIK3R1) 103224900(PIK3R3) 103234391(PIK3R2)
CATY: 105571321(PIK3R2) 105594576(PIK3R3) 105599262(PIK3R1)
PANU: 100510873(PIK3R1) 101002971(PIK3R3) 101009981(PIK3R2)
TGE: 112612001(PIK3R2) 112614522(PIK3R3) 112625914(PIK3R1)
MLEU: 105531763(PIK3R3) 105543389(PIK3R1) 105547376(PIK3R2)
RRO: 104662124(PIK3R3) 104675620(PIK3R1) 104680672(PIK3R2)
RBB: 108534276(PIK3R2) 108535636(PIK3R3) 108541175(PIK3R1)
TFN: 117065206(PIK3R1) 117075022(PIK3R2) 117092662(PIK3R3)
PTEH: 111539891(PIK3R1) 111548774(PIK3R3) 111554247(PIK3R2)
CANG: 105500411(PIK3R2) 105515019(PIK3R3) 105524169(PIK3R1)
CJC: 100392639(PIK3R1) 100406689(PIK3R2) 100414659(PIK3R3)
SBQ: 101032496(PIK3R1) 101033359(PIK3R2) 101050592(PIK3R3)
CIMI: 108284538(PIK3R2) 108295514(PIK3R1) 108312772(PIK3R3)
CSYR: 103262537(PIK3R1) 103272136(PIK3R3)
MMUR: 105855026(PIK3R2) 105877483(PIK3R3) 105881219(PIK3R1)
LCAT: 123634187 123639706(PIK3R2) 123648578(PIK3R1)
PCOQ: 105814042(PIK3R3) 105818191(PIK3R2) 105826612(PIK3R1)
OGA: 100949858(PIK3R1) 100952580(PIK3R3) 100956838(PIK3R2)
MMU: 18708(Pik3r1) 18709(Pik3r2) 18710(Pik3r3)
MCAL: 110292624 110299855(Pik3r2) 110308009(Pik3r1)
MPAH: 110322865(Pik3r3) 110328811(Pik3r1) 110336420(Pik3r2)
RNO: 25513(Pik3r1) 29741(Pik3r2) 60664(Pik3r3)
MCOC: 116069491(Pik3r2) 116083721(Pik3r1) 116096465(Pik3r3)
ANU: 117708961 117721973(Pik3r2) 117723761(Pik3r1)
MUN: 110549145(Pik3r2) 110553683(Pik3r1) 110563512(Pik3r3)
CGE: 100750761(Pik3r1) 100771181(Pik3r2) 100774067
MAUA: 101829045(Pik3r2) 101831400 101835039(Pik3r1)
PROB: 127217216(Pik3r2) 127220972(Pik3r1) 127225197(Pik3r3)
PLEU: 114688966(Pik3r2) 114703850(Pik3r1) 114706924(Pik3r3)
MORG: 121448002 121455952(Pik3r1) 121462841(Pik3r2)
AAMP: 119808979(Pik3r1) 119812102(Pik3r2) 119817743
NGI: 103726879(Pik3r2) 103730305(Pik3r3) 103738715(Pik3r1)
HGL: 101703691(Pik3r1) 101717096(Pik3r3) 101718815(Pik3r2)
CPOC: 100730242(Pik3r1) 100734044(Pik3r2) 100734206
CCAN: 109682432(Pik3r3) 109682554 109694666(Pik3r1)
DORD: 105985370(Pik3r1) 105986178(Pik3r3)
DSP: 122100872(Pik3r2) 122108047 122117343(Pik3r1)
PLOP: 125348916(Pik3r2) 125355095(Pik3r3) 125367817(Pik3r1)
MMMA: 107139438(Pik3r1) 107141811(Pik3r3) 107145061(Pik3r2)
OPI: 101517982(PIK3R1) 101528030 101532354(PIK3R2)
TUP: 102469401(PIK3R2) 102484444(PIK3R3) 102484500(PIK3R1)
GVR: 103585463(PIK3R3) 103593683(PIK3R2) 103608454(PIK3R1)
CFA: 100856339 487235(PIK3R1) 609956(PIK3R2)
CLUD: 112642563(PIK3R3) 112660199(PIK3R1) 112666735(PIK3R2)
VVP: 112913170(PIK3R2) 112914774 112935820(PIK3R1)
VLG: 121481416 121494738(PIK3R2) 121496480(PIK3R1)
NPO: 129513452(PIK3R1) 129520803(PIK3R3) 129522073(PIK3R2)
AML: 100467916(PIK3R3) 100475291(PIK3R2) 100483828(PIK3R1)
UMR: 103663617(PIK3R1) 103670766(PIK3R3) 103675162(PIK3R2)
UAH: 113254730(PIK3R3) 113255266(PIK3R1) 113256705(PIK3R2)
UAR: 123779926(PIK3R2) 123793748(PIK3R3) 123800228(PIK3R1)
MPUF: 101680399(PIK3R2) 101683594 101683710(PIK3R1)
MNP: 132000809(PIK3R3) 132011173(PIK3R2) 132028693(PIK3R1)
MLK: 131810162(PIK3R3) 131823754(PIK3R2) 131832309(PIK3R1)
NVS: 122899916(PIK3R3) 122909588(PIK3R2) 122918946(PIK3R1)
ORO: 101370100(PIK3R1) 101371800(PIK3R2) 101374787(PIK3R3)
EJU: 114224308 114224631(PIK3R1) 114226659(PIK3R2)
ZCA: 113911688(PIK3R3) 113917179(PIK3R2) 113928897(PIK3R1)
MLX: 118006042(PIK3R2) 118016863(PIK3R1) 118019468(PIK3R3)
NSU: 110574558(PIK3R2) 110575009 110591287(PIK3R1)
LWW: 102726443(PIK3R2) 102728383 102751021(PIK3R1)
FCA: 100271864(PIK3R1) 101093286 101093586(PIK3R2)
PYU: 121011002(PIK3R2) 121014969(PIK3R1) 121027050(PIK3R3)
PCOO: 112861619(PIK3R1) 112868847
PBG: 122480440(PIK3R3) 122487093(PIK3R2) 122489641(PIK3R1)
PVIV: 125150373(PIK3R2) 125161995(PIK3R1) 125172124(PIK3R3)
PTG: 102949853(PIK3R3) 102952993(PIK3R1) 102967709(PIK3R2)
PPAD: 109247606(PIK3R2) 109266953(PIK3R3) 109275060(PIK3R1)
HHV: 120219997(PIK3R1) 120239233(PIK3R2) 120247089
BTA: 282307(PIK3R1) 282308(PIK3R2) 286865(PIK3R3)
BOM: 102266922(PIK3R1) 102280296(PIK3R3) 102286868(PIK3R2)
BIU: 109556345 109561418(PIK3R2) 109574805(PIK3R1)
BBUB: 102395384 102404517(PIK3R2) 102415109(PIK3R1)
BBIS: 104992716 104994333(PIK3R3) 104998445(PIK3R1)
CHX: 102170135(PIK3R2) 102179343(PIK3R3) 102188710(PIK3R1)
OAS: 101111546(PIK3R2) 101121455(PIK3R1) 101123247(PIK3R3)
BTAX: 128044474(PIK3R3) 128050540(PIK3R2) 128066235(PIK3R1)
ODA: 120856226 120864210(PIK3R2) 120879604(PIK3R1)
CCAD: 122437038(PIK3R3) 122440740(PIK3R2) 122454626(PIK3R1)
MBEZ: 129540801(PIK3R3) 129553207(PIK3R1) 129559156(PIK3R2)
SSC: 100511937 100623707(PIK3R1) 100739510(PIK3R2)
CFR: 102505690 102513205(PIK3R2) 102520923(PIK3R1)
CBAI: 105064416(PIK3R1) 105065663(PIK3R3) 105082679(PIK3R2)
CDK: 105084758(PIK3R1) 105092913 105101867(PIK3R2)
VPC: 102532395(PIK3R1) 102536225 102536302(PIK3R2)
BACU: 103007464(PIK3R1) 103008077(PIK3R3) 103009307(PIK3R2)
BMUS: 118891709(PIK3R1) 118892996(PIK3R2) 118901944
LVE: 103070370(PIK3R1) 103078725(PIK3R3) 103083960(PIK3R2)
OOR: 101277568(PIK3R3) 101281352(PIK3R2) 101285437(PIK3R1)
DLE: 111166652(PIK3R2) 111175760 111185984(PIK3R1)
PCAD: 102975555(PIK3R3) 102991192(PIK3R1) 102991779(PIK3R2)
PSIU: 116742613 116750604(PIK3R1) 116751944(PIK3R2)
NASI: 112400438 112404930(PIK3R1) 112414874(PIK3R2)
ECB: 100050227(PIK3R1) 100052122 100146348(PIK3R2)
EPZ: 103548220(PIK3R1) 103551868(PIK3R3) 103561550(PIK3R2)
EAI: 106822593 106824993(PIK3R2) 106840141(PIK3R1)
MYB: 102242302(PIK3R1) 102253405(PIK3R2) 102258430(PIK3R3)
MYD: 102753036(PIK3R1) 102760468(PIK3R3) 102763670(PIK3R2)
MMYO: 118656203(PIK3R1) 118657573(PIK3R2) 118675217
MLF: 102419324 102426106(PIK3R3) 102427890(PIK3R1) 102429230(PIK3R2) 102441522
PKL: 118703803(PIK3R1) 118722550 118725879(PIK3R2)
EFUS: 103294784(PIK3R3) 103299551(PIK3R2) 103305161(PIK3R1)
MNA: 107526728(PIK3R3) 107529317(PIK3R1) 107535325(PIK3R2)
DRO: 112305224(PIK3R2) 112314466 112321016(PIK3R1)
SHON: 118975178(PIK3R2) 118982454(PIK3R3) 118998595(PIK3R1)
AJM: 119046830(PIK3R2) 119052227 119053288(PIK3R1)
PDIC: 114496100(PIK3R3) 114501063(PIK3R1) 114502559(PIK3R2)
PHAS: 123824527(PIK3R1) 123828291(PIK3R2) 123832298
MMF: 118616460(PIK3R2) 118626685 118642883(PIK3R1)
PPAM: 129069407(PIK3R3) 129074590(PIK3R1) 129074969(PIK3R2)
HAI: 109373811(PIK3R3) 109382484(PIK3R2) 109395865(PIK3R1)
RFQ: 117024531(PIK3R1) 117027160 117038261(PIK3R2)
PALE: 102879163(PIK3R1) 102879453(PIK3R2) 102891637
PGIG: 120606549(PIK3R2) 120608247(PIK3R1) 120620206
PVP: 105296605(PIK3R2) 105297140 105299371(PIK3R1)
RAY: 107498704(PIK3R1) 107517899(PIK3R3) 107521668(PIK3R2)
MJV: 108383561(PIK3R2) 108390475(PIK3R1) 108395975
TOD: 119237093(PIK3R3) 119241117(PIK3R2) 119260810(PIK3R1)
SARA: 101540938(PIK3R2) 101541868(PIK3R1) 101547106(PIK3R3)
SETR: 126001552(PIK3R1) 126011086(PIK3R3) 126030200(PIK3R2)
LAV: 100653731(PIK3R1) 100665045(PIK3R2) 100675496(PIK3R3)
ETF: 101655654(PIK3R1) 101657368 101659995(PIK3R2)
DNM: 101423744 101433347(PIK3R2) 101435351(PIK3R1)
MDO: 100019317(PIK3R1) 100032726(PIK3R2) 100616957(PIK3R3)
SHR: 100924976(PIK3R1) 100926892(PIK3R2) 100935230(PIK3R3)
PCW: 110209293(PIK3R3) 110216530(PIK3R1) 110223395(PIK3R2)
OAA: 100080187(PIK3R2) 100082075(PIK3R3) 103167126(PIK3R1)
GGA: 427171(PIK3R1) 429096(PIK3R3) 771142(PIK3R2)
PCOC: 116234220 116235709(PIK3R2) 116239922(PIK3R1)
CJO: 107305909(PIK3R1) 107317608 107325533(PIK3R2)
TPAI: 128072383(PIK3R3) 128074427(PIK3R1) 128088982(PIK3R2)
LMUT: 125685084(PIK3R2) 125686542(PIK3R1) 125694122(PIK3R3)
NMEL: 110388756(PIK3R2) 110389564(PIK3R1) 110402756(PIK3R3)
APLA: 101795759 101799717(PIK3R1) 101803461(PIK3R2)
ACYG: 106033049(PIK3R3) 106042106(PIK3R1) 106045000(PIK3R2)
CATA: 118243598(PIK3R3) 118251494(PIK3R1) 118258749(PIK3R2)
AFUL: 116491758 116499089(PIK3R2) 116501170(PIK3R1)
TGU: 100221185 100223949(PIK3R1) 100226234(PIK3R2)
LSR: 110469696 110472594(PIK3R1) 110478008(PIK3R2)
SCAN: 103814989 103821918(PIK3R2) 103823133(PIK3R1) 115483908
PMOA: 120498082(PIK3R2) 120502343(PIK3R1) 120503174
OTC: 121341222(PIK3R1) 121341824(PIK3R2) 121344995
PRUF: 121355311(PIK3R1) 121361353(PIK3R2) 121361937
GFR: 102032353(PIK3R1) 102035891(PIK3R2) 102039817(PIK3R3)
FAB: 101811808(PIK3R2) 101812251(PIK3R3) 101820843(PIK3R1)
OMA: 130256118(PIK3R3) 130264528(PIK3R2) 130265049(PIK3R1)
PHI: 102106897(PIK3R2) 102112482(PIK3R3) 102114750(PIK3R1)
PMAJ: 107208273 107215603(PIK3R2) 107216262(PIK3R1)
CCAE: 111933104(PIK3R3) 111940405(PIK3R2) 111941370(PIK3R1)
CCW: 104686712(PIK3R1) 104695234 104696977(PIK3R2)
CBRC: 103621908(PIK3R3) 103622106(PIK3R2) 103624307(PIK3R1)
ZAB: 102060529(PIK3R2) 102070553(PIK3R1) 102072114
ZLE: 135451300(PIK3R3) 135458779(PIK3R2) 135459365(PIK3R1)
ACHL: 103800635(PIK3R3) 103807634(PIK3R2) 103807943(PIK3R1)
SVG: 106850601(PIK3R3) 106856206(PIK3R1) 106857134(PIK3R2)
MMEA: 130572286 130582513 130586288(PIK3R2) 130589279(PIK3R3)
HRT: 120756367(PIK3R3) 120763569(PIK3R2) 120765192(PIK3R1)
FPG: 101913266(PIK3R3) 101915242(PIK3R2) 101924523(PIK3R1)
FCH: 102056135(PIK3R1) 102057083(PIK3R2) 102059517
CLV: 102084272(PIK3R3) 102084904(PIK3R2) 102092838(PIK3R1)
EGZ: 104124880(PIK3R1) 104126253(PIK3R3) 104135641(PIK3R2)
NNI: 104015409(PIK3R3) 104018715(PIK3R2)
PCRI: 104027580(PIK3R3) 104038243(PIK3R1)
PLET: 104621033(PIK3R2) 104623180(PIK3R3)
EHS: 104504642(PIK3R1) 104508880(PIK3R3) 104512091(PIK3R2)
PCAO: 104044331(PIK3R1) 104051690
ACUN: 113483193 113489298(PIK3R2) 113489600(PIK3R1)
TALA: 104363088(PIK3R1) 104365196(PIK3R2) 104366887
PADL: 103919124(PIK3R3) 103919717(PIK3R1) 103926435(PIK3R2)
AFOR: 103893369(PIK3R1) 103899302(PIK3R2) 103905595(PIK3R3)
ACHC: 115337134(PIK3R1) 115348975 115349575(PIK3R2) 121233034
HALD: 104315723(PIK3R3) 104319651(PIK3R1) 104323052
HLE: 104828487(PIK3R2) 104839910(PIK3R1) 104841050(PIK3R3)
CCRI: 104158448(PIK3R3) 104160278(PIK3R2) 104169467(PIK3R1)
CSTI: 104553746(PIK3R1) 104559613(PIK3R3)
CMAC: 104478394(PIK3R3) 104478819(PIK3R1)
MUI: 104542097(PIK3R3) 104543772(PIK3R2) 104544758(PIK3R1)
BREG: 104634362 104634486(PIK3R1) 104641031(PIK3R3) 104643797
FGA: 104071302(PIK3R1) 104072668(PIK3R2) 104083214(PIK3R3)
GSTE: 104257515(PIK3R1) 104259647(PIK3R3) 104262659
LDI: 104341169(PIK3R3) 104350040(PIK3R1) 104350597(PIK3R2)
MNB: 103768794(PIK3R3) 103776111(PIK3R1)
OHA: 104330905(PIK3R1) 104339461(PIK3R2) 104339506(PIK3R3)
NNT: 104403579(PIK3R3) 104410866(PIK3R1) 104413180
SHAB: 115611400 115618216(PIK3R2) 115619483(PIK3R1)
DPUB: 104300791(PIK3R2) 104301577(PIK3R3) 104306691(PIK3R1)
PGUU: 104459755(PIK3R1) 104462451(PIK3R3) 104470133
ACAR: 104523932(PIK3R1) 104526170 104528001(PIK3R3)
CPEA: 104388868(PIK3R2) 104395652(PIK3R1) 104396688(PIK3R3)
AVIT: 104271453(PIK3R1) 104273204 104277649(PIK3R3)
CVF: 104285739(PIK3R1) 104286266(PIK3R3) 104290423 104295401(PIK3R2)
RTD: 128900619(PIK3R2) 128902186(PIK3R1) 128913752(PIK3R3)
CUCA: 104060172(PIK3R3) 104060960(PIK3R2) 104064011(PIK3R1)
TEO: 104372178 104374535(PIK3R1) 104382213(PIK3R3)
BRHI: 104495015(PIK3R1) 104499813 104502170(PIK3R3)
AAM: 106485939(PIK3R3) 106495610(PIK3R2) 106499441(PIK3R1)
AROW: 112966717(PIK3R2) 112969925(PIK3R1) 112976037
NPD: 112942696 112943951(PIK3R2) 112945237(PIK3R1)
TGT: 104574053(PIK3R3) 104575770(PIK3R1) 104577735
DNE: 112985410 112986570(PIK3R2) 112987101(PIK3R1)
SCAM: 104145800(PIK3R2) 104147993(PIK3R3) 104152968(PIK3R1)
ASN: 102377899(PIK3R2) 102380057 102382060(PIK3R1)
AMJ: 102567863(PIK3R2) 102570922(PIK3R1) 106737141(PIK3R3)
CPOO: 109307425(PIK3R3) 109307980(PIK3R1) 109312353(PIK3R2)
GGN: 109286709(PIK3R3) 109294997(PIK3R2) 109297752(PIK3R1)
PSS: 102449585(PIK3R1) 102457516
CMY: 102933845(PIK3R2) 102941819 102945631(PIK3R1)
CCAY: 125626958(PIK3R2) 125636597(PIK3R1) 125640830(PIK3R3)
DCC: 119848340(PIK3R2) 119855572(PIK3R1) 119859766
CPIC: 101945673(PIK3R2) 101947423 101953817(PIK3R1)
TST: 117868848(PIK3R2) 117879552(PIK3R1) 117881251
CABI: 116826231(PIK3R2) 116839230 116839322(PIK3R1)
MRV: 120370714 120391575(PIK3R2) 120407838(PIK3R1)
ACS: 100554618(pik3r3) 100555182(pik3r2) 100556883(pik3r1)
ASAO: 132767034(PIK3R1) 132773868(PIK3R3) 132780959(PIK3R2)
PVT: 110072561(PIK3R2) 110073778(PIK3R3) 110073951(PIK3R1)
SUND: 121923252(PIK3R1) 121928626
PBI: 103055280(PIK3R2) 103065132 103065975(PIK3R1)
PMUR: 107282273(PIK3R2) 107283596 107286152(PIK3R1)
CTIG: 120297322 120305981(PIK3R2) 120318076(PIK3R1)
TSR: 106538977(PIK3R1) 106543200(PIK3R3) 106552169
PGUT: 117664160(PIK3R3) 117677371(PIK3R2) 117679253(PIK3R1)
APRI: 131188166(PIK3R2) 131191378(PIK3R1) 131196302(PIK3R3)
PTEX: 113434955(PIK3R2) 113440623 113447320(PIK3R1)
NSS: 113410978 113413935(PIK3R1) 113414090(PIK3R2)
VKO: 123029047 123031202(PIK3R1)
PMUA: 114588236(PIK3R2) 114599062 114606162(PIK3R1)
PRAF: 128405629(PIK3R2) 128415836(PIK3R3) 128423036(PIK3R1)
ZVI: 118077038(PIK3R1) 118085906(PIK3R2) 118088990
HCG: 128324386(PIK3R3) 128344776(PIK3R1) 128346633(PIK3R2)
GJA: 107108905(PIK3R1) 107119473(PIK3R3) 107121678(PIK3R2)
STOW: 125432754 125433242(PIK3R3) 125436164(PIK3R1)
EMC: 129329994(PIK3R2) 129331257(PIK3R3) 129334239(PIK3R1)
XLA: 108706884(pik3r2.S) 108713027(pik3r2.L) 399202(pik3r1.S) 443964(pik3r1.L) 446786(pik3r3.S) 447594(pik3r3.L)
XTR: 100486835(pik3r1) 100497001(pik3r2) 549983(pik3r3)
NPR: 108789013(PIK3R2) 108797628(PIK3R1) 108802963
RTEM: 120916053(PIK3R2) 120923203 120928855(PIK3R1)
BBUF: 120978688(PIK3R3) 120989607(PIK3R2) 120992399(PIK3R1)
BGAR: 122924744(PIK3R1) 122946211(PIK3R2)
MUO: 115463034(PIK3R1) 115471738 115480521(PIK3R2)
GSH: 117346336 117353683(PIK3R1) 117365925(PIK3R2)
DRE: 100000252(pik3r3b) 404211(pik3r2) 557176(pik3r1)
PTET: 122344708(pik3r1) 122346452(pik3r3b) 122347155 122362518(pik3r2)
LROH: 127164849(pik3r1) 127166520(pik3r3b) 127176088(pik3r2)
OMC: 131540458(pik3r1) 131541975(pik3r3b) 131552189(pik3r2)
PPRM: 120460087(pik3r3b) 120468781(pik3r3a) 120468782 120472399(pik3r1) 120482851(pik3r2)
RKG: 130070871(pik3r2) 130091371 130099701(pik3r1)
MAMB: 125250270(pik3r3a) 125250735(pik3r2) 125267879(pik3r1) 125273996(pik3r3b)
TROS: 130555087(pik3r2) 130556269(pik3r3b) 130566832(pik3r1)
TDW: 130417757(pik3r2) 130418890(pik3r1) 130424413(pik3r3b)
MANU: 129441166(pik3r1) 129442260(pik3r2) 129451059(pik3r3b)
IPU: 108260231 108272037(pik3r3b)
IFU: 128603480(pik3r1) 128614576(pik3r3b)
PHYP: 113531632(pik3r1) 113538265
SMEO: 124379064(pik3r1) 124392406(pik3r3b)
TFD: 113641408(pik3r1) 113647639(pik3r3b)
TVC: 132840612(pik3r1) 132844284(pik3r3b)
TRN: 134303620(pik3r1) 134317232(pik3r3b)
AMEX: 103029972(pik3r3) 103035767 103046618(pik3r1) 111190801
CMAO: 118808170(pik3r3b) 118814571(pik3r1)
CHAR: 105896427 105900602(pik3r2) 105902185(pik3r1) 105913142(pik3r3b) 122129273 122133228
TFS: 130517020(pik3r1) 130525966 130528394 130528931(pik3r3b) 130538567 130539592(pik3r2)
PGEO: 117445092(pik3r3b) 117445659 117455737(pik3r1) 117462047(pik3r2) 117462274
GACU: 117532612(pik3r2) 117535004 117542274 117545568 117560597(pik3r3b) 117561441(pik3r1)
EMAC: 134865729 134865816(pik3r2) 134868191(pik3r1) 134869270(pik3r3b) 134869506 134873278
ELY: 117252529 117254143 117254148(pik3r3b) 117269552(pik3r1) 117271502 117271508(pik3r2)
EFO: 125890643 125895325(pik3r3b) 125896428 125901675(pik3r2) 125902071 125905500(pik3r1)
PLEP: 121938061 121939825 121951302 121951926(pik3r2) 121959511(pik3r1) 121962939(pik3r3b)
SLUC: 116037246(pik3r2) 116045807 116053059 116056635 116056995(pik3r3b) 116062801(pik3r1)
ECRA: 117944918 117950300 117950796(pik3r3b) 117953620(pik3r2) 117954000 117959815(pik3r1)
GAT: 120815842(pik3r2) 120816124 120823475 120823622(pik3r3b) 120830750 120831616(pik3r1)
PPUG: 119209332(pik3r2) 119209420 119216917 119216976(pik3r3b) 119224672 119226302(pik3r1)
AFB: 129094332(pik3r3b) 129094609 129101175 129102021(pik3r1) 129110782(pik3r2) 129112007
CLUM: 117729683(pik3r3b) 117729698 117736025 117740185(pik3r1) 117746515 117746960(pik3r2)
PSWI: 130193807(pik3r3b) 130194122 130196195 130197660 130197673(pik3r2) 130205168(pik3r1)
MSAM: 119891547 119900224(pik3r3b) 119900503 119902234(pik3r2) 119902368 119914041(pik3r1)
SCHU: 122865334(pik3r1) 122876770 122877580(pik3r3b) 122878127 122887224(pik3r2) 122887535
CUD: 121509697 121512025(pik3r3b) 121512376 121519790 121519794(pik3r2) 121524754(pik3r1)
ALAT: 119011069 119011087(pik3r2) 119019184 119028110 119028425(pik3r3b) 119029893(pik3r1)
CSAI: 133451344 133452923(pik3r2) 133453078 133455087(pik3r1) 133457924(pik3r3b) 133458551
PRET: 103463201(pik3r3) 103463319 103470780 103473324(pik3r1) 103478998 103479173(pik3r2)
GMU: 124869460(pik3r2) 124870480 124872596(pik3r1) 124873683 124873763(pik3r3b) 124877742
KMR: 108234365 108238336 108244850(pik3r2) 108245882 108247561(pik3r3b) 108250884(pik3r1)
MCEP: 124996387(pik3r1) 125009281(pik3r3b) 125009744 125010445(pik3r2) 125011199 125012779
HHIP: 117760130(pik3r3b) 117760625 117768381 117771255(pik3r1) 117777997(pik3r2) 117778159
HSP: 118114686 118117905 118117936(pik3r2) 118120902 118120979(pik3r3b) 118125392(pik3r1)
PPLT: 128438364 128448214 128448269(pik3r3b) 128454882 128455193(pik3r2) 128462281(pik3r1)
SMAU: 118284803(pik3r1) 118310786(pik3r2) 118311687 118313435 118317729(pik3r3b) 118318227
XGL: 120790713 120791111(pik3r3b) 120799080(pik3r2) 120799460 120805057 120806252(pik3r1)
MALB: 109957384 109965201(pik3r3) 109966856 109969301(pik3r2) 109969763(pik3r1) 109970672
BSPL: 114844064 114845055(pik3r2) 114854767(pik3r3b) 114854785 114861410 114866713(pik3r1)
PKI: 111834821(pik3r3) 111835615(pik3r1) 111847640 111856594 111860386(pik3r2)
AANG: 118206252 118212644(pik3r1) 118225456(pik3r2) 118225588(pik3r3b) 118228853
LOC: 102687995(pik3r2) 102693436(pik3r3) 102696821(pik3r1)
PSEX: 120514216(pik3r3b) 120532558(pik3r1) 120537570(pik3r2)
LCM: 102348007(PIK3R3) 102353218(PIK3R1)
RTP: 109916739 109917303(pik3r3b)
CPLA: 122558110(pik3r1)
HOC: 132819107(pik3r3b) 132822331(pik3r1)
LERI: 129695104 129700904(pik3r3b)
PMRN: 116948911
LRJ: 133352049
BFO: 118432571
BBEL: 109475961
CIN: 100184893
SCLV: 120335427
SPU: 588766
LPIC: 129270766
APLC: 110977729
SKO: 100372481
DME: Dmel_CG2699(Pi3K21B)
DER: 6543312
DSE: 6621105
DSI: Dsimw501_GD23016(Dsim_GD23016)
DSR: 110187562
DPO: 4817932
DPE: 6593764
DMN: 108163765
DWI: 6651829
DGR: 6562048
DAZ: 108609449
DNV: 108650034
DHE: 111602464
DVI: 6628686
CCAT: 101450793
BOD: 106614981
BDR: 105229287
AOQ: 129247242
TDA: 119688989
MDE: 101896300
SCAC: 106081749
LCQ: 111686430
LSQ: 119611134
GFS: 119633187
CLON: 129613108
ACOZ: 120953852
AARA: 120897556
AMER: 121592513
ASTE: 118512835
AFUN: 125770071
AMOU: 128300726
AAG: 5578257
AALB: 109409609
ASUA: 134210579
CPII: 120413155
CNS: 116337413
BCOO: 119085220
AME: 408577
ACER: 107993600
ALAB: 122719497
ADR: 102674501
AFLR: 100869097
BIM: 100743083
BBIF: 117209300
BVK: 117237500
BVAN: 117156020
BTER: 100643962
BAFF: 126919609
BPYO: 122565623
BPAS: 132910786
FVI: 122536883
CCAL: 108629871
OBB: 114871807
OLG: 117600869
MGEN: 117229216
NMEA: 116432267
CGIG: 122399909
SOC: 105195470
MPHA: 105831984
AEC: 105151922
ACEP: 105620878
PBAR: 105430848
VEM: 105567561
HST: 105192434
DQU: 106748226
CFO: 105255336
LHU: 105667777
PGC: 109854747
OBO: 105284404
PCF: 106792271
PFUC: 122514468
VPS: 122629872
VCRB: 124425716
VVE: 124949563
NVI: 100122747
CSOL: 105361583
LHT: 122509398
LBD: 127288195
MDL: 103580680
CGLO: 123259870
FAS: 105268850
DAM: 107037299
DSM: 124410830
NPT: 124220654
NFB: 124183956
NLO: 107219243
NVG: 124306415
TCA: 100141888
DPA: 109540864
SOY: 115876841
AGRG: 126748963
ATD: 109595073
AGB: 108916999
LDC: 111507049
DVV: 114340898
NVL: 108559788
PPYR: 116166071
OTU: 111425557
BMOR: 100158253(Pi3k60)
BMAN: 114245941
MSEX: 115453059
BANY: 112044673
MJU: 123869620
NIQ: 126771312
VCD: 124531686
MCIX: 123655842
PMAC: 106714800
PPOT: 106106684
PXU: 106127430
PRAP: 110992252
PBX: 123717367
PNAP: 125055262
ZCE: 119834537
CCRC: 123693845
LSIN: 126965472
AAGE: 121739614
HAW: 110370679
HZE: 124629583
TNL: 113497575
SLIU: 111348252
OFU: 114365514
ATRA: 106129178
PXY: 105388447
PGW: 126368434
LGLY: 125226511
CCRN: 123302198
AGS: 114129704
RMD: 113553291
ACOO: 126838240
BTAB: 109032766
CLEC: 106664096
HHAL: 106692677
NLU: 111047698
HVI: 124369941
FOC: 113201758
TPAL: 117651645
FCD: 110845224
PVM: 113810630
PCHN: 125038179
PMOO: 119586926
HAME: 121864257
PCLA: 123745389
CQD: 128685383
PTRU: 123499232
ESN: 126990852
MNZ: 135210751
HAZT: 108677079
EAF: 111697024
LSM: 121114447
TCF: 131893673
PPOI: 119110593
DSV: 119433196
RSAN: 119404584
RMP: 119181020
VDE: 111248584
VJA: 111273172
DPTE: 113798240
PMEO: 129591294
CEL: CELE_Y110A7A.10(aap-1)
CBR: CBG_10815(Cbr-aap-1)
BMY: BM_BM7280(Bma-aap-1)
TSP: Tsp_02388
BGT: 106064965
CRG: 105321629
CVN: 111118072
CANU: 128165077
OED: 125669491
OBI: 106879157
OSN: 115223514
LJP: 135470408
EGL: EGR_06563
LLON: 135486959
NVE: 5520340
EPA: 110239539
ATEN: 116307342
ADF: 107335159
AMIL: 114952874
PDAM: 113679985
SPIS: 111326832
DGT: 114527321
XEN: 124440213
HSY: 130630392
 » show all
Reference
PMID:1849461
  Authors
Skolnik EY, Margolis B, Mohammadi M, Lowenstein E, Fischer R, Drepps A, Ullrich A, Schlessinger J
  Title
Cloning of PI3 kinase-associated p85 utilizing a novel method for expression/cloning of target proteins for receptor tyrosine kinases.
  Journal
Cell 65:83-90 (1991)
DOI:10.1016/0092-8674(91)90410-Z
  Sequence
[hsa:5295]
Reference
PMID:9582025
  Authors
Janssen JW, Schleithoff L, Bartram CR, Schulz AS
  Title
An oncogenic fusion product of the phosphatidylinositol 3-kinase p85beta subunit and HUMORF8, a putative deubiquitinating enzyme.
  Journal
Oncogene 16:1767-72 (1998)
DOI:10.1038/sj.onc.1201695
  Sequence
[hsa:5296]
Reference
PMID:9524259
  Authors
Dey BR, Furlanetto RW, Nissley SP
  Title
Cloning of human p55 gamma, a regulatory subunit of phosphatidylinositol 3-kinase, by a yeast two-hybrid library screen with the insulin-like growth factor-I receptor.
  Journal
Gene 209:175-83 (1998)
DOI:10.1016/S0378-1119(98)00045-6
  Sequence
[hsa:8503]
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