KEGG   PATHWAY: ko05200
Entry
ko05200                     Pathway                                
Name
Pathways in cancer
Class
Human Diseases; Cancer: overview
Pathway map
ko05200  Pathways in cancer
ko05200

Orthology
K00182  WNT2; wingless-type MMTV integration site family, member 2
K00312  WNT3; wingless-type MMTV integration site family, member 3
K00355  NQO1; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]
K00408  WNT4; wingless-type MMTV integration site family, member 4
K00444  WNT5; wingless-type MMTV integration site family, member 5
K00445  WNT6; wingless-type MMTV integration site family, member 6
K00510  HMOX1; heme oxygenase 1 [EC:1.14.14.18]
K00572  WNT7; wingless-type MMTV integration site family, member 7
K00714  WNT8; wingless-type MMTV integration site family, member 8
K00799  GST; glutathione S-transferase [EC:2.5.1.18]
K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K01064  WNT9; wingless-type MMTV integration site family, member 9
K01110  PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K01115  PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K01116  PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K01313  F2; coagulation factor II (thrombin) [EC:3.4.21.5]
K01351  KLK3, PSA; semenogelase [EC:3.4.21.77]
K01357  WNT10; wingless-type MMTV integration site family, member 10
K01384  WNT11; wingless-type MMTV integration site family, member 11
K01388  MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
K01398  MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
K01403  MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K01558  WNT16; wingless-type MMTV integration site family, member 16
K01679  E4.2.1.2B, fumC, FH; fumarate hydratase, class II [EC:4.2.1.2]
K02084  APAF1; apoptotic protease-activating factor
K02085  APC; adenomatosis polyposis coli protein
K02089  CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091  CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K02105  CTNNB1; catenin beta 1
K02157  AXIN1; axin 1
K02158  BAD; Bcl-2-antagonist of cell death
K02159  BAX; apoptosis regulator BAX
K02161  BCL2; apoptosis regulator Bcl-2
K02183  CALM; calmodulin
K02187  CASP3; caspase 3 [EC:3.4.22.56]
K02206  CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K02219  CKS1; cyclin-dependent kinase regulatory subunit CKS1
K02235  FZD2; frizzled 2
K02329  FZD3; frizzled 3
K02353  DVL; segment polarity protein dishevelled
K02354  FZD4, fz4, CD344; frizzled 4
K02373  FADD; FAS-associated death domain protein
K02375  FZD5_8, fz2; frizzled 5/8
K02376  FZD6; frizzled 6
K02432  FZD1_7, fz; frizzled 1/7
K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
K02599  NOTCH1; Notch 1
K02620  TCF7, TCF-1; transcription factor 7
K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02677  PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K02678  ETS1, pnt; C-ets-1
K02833  HRAS; GTPase HRas
K02842  FZD9_10, CD349_50; frizzled 9/10
K03068  LRP5_6; low density lipoprotein receptor-related protein 5/6
K03069  FRAT1; frequently rearranged in advanced T-cell lymphomas 1
K03083  GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
K03096  FRAT2; frequently rearranged in advanced T-cell lymphomas 2
K03099  SOS; son of sevenless
K03172  TRAF1; TNF receptor-associated factor 1
K03173  TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K03174  TRAF3; TNF receptor-associated factor 3
K03175  TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K03176  NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K03209  WNT1; wingless-type MMTV integration site family, member 1
K03347  CUL1, CDC53; cullin 1
K03511  POLK; DNA polymerase kappa [EC:2.7.7.7]
K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
K03870  CUL2; cullin 2
K03871  VHL; von Hippel-Lindau disease tumor supressor
K03872  ELOC, TCEB1; elongin-C
K03873  ELOB, TCEB2; elongin-B
K03875  SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K03898  KNG, BK; kininogen
K03914  F2R, PAR1; coagulation factor II (thrombin) receptor
K03915  BDKRB1; bradykinin receptor B1
K03916  BDKRB2; bradykinin receptor B2
K04079  HSP90A, htpG; molecular chaperone HtpG
K04166  AGTR1; angiotensin II receptor type 1
K04189  CXCR4, CD184; C-X-C chemokine receptor type 4
K04197  EDNRA; endothelin receptor type A
K04198  EDNRB; endothelin receptor type B
K04236  F2RL3, PAR4; coagulation factor II (thrombin) receptor-like 3
K04258  PTGER1; prostaglandin E receptor 1
K04259  PTGER2; prostaglandin E receptor 2
K04260  PTGER3; prostaglandin E receptor 3
K04261  PTGER4; prostaglandin E receptor 4
K04273  LPAR6, P2RY5; lysophosphatidic acid receptor 6
K04275  LPAR4, GPR23; lysophosphatidic acid receptor 4
K04289  LPAR1, EDG2; lysophosphatidic acid receptor 1
K04291  LPAR2, EDG4; lysophosphatidic acid receptor 2
K04294  LPAR3, EDG7; lysophosphatidic acid receptor 3
K04345  PKA; protein kinase A [EC:2.7.11.11]
K04346  GNA12; guanine nucleotide-binding protein subunit alpha-12
K04347  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04350  RASGRP1; RAS guanyl-releasing protein 1
K04357  EGF; epidermal growth factor
K04358  FGF; fibroblast growth factor
K04359  PDGFA; platelet-derived growth factor subunit A
K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K04362  FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K04363  PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K04364  GRB2; growth factor receptor-bound protein 2
K04365  BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04375  ELK1; ETS domain-containing protein Elk-1
K04377  MYC; Myc proto-oncogene protein
K04379  FOS; proto-oncogene protein c-fos
K04385  AXIN2; axin 2
K04388  TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04389  TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K04392  RAC1; Ras-related C3 botulinum toxin substrate 1
K04393  CDC42; cell division control protein 42
K04397  CASP7; caspase 7 [EC:3.4.22.60]
K04398  CASP8; caspase 8 [EC:3.4.22.61]
K04399  CASP9; caspase 9 [EC:3.4.22.62]
K04402  GADD45; growth arrest and DNA-damage-inducible protein
K04411  STK4, MST1; serine/threonine kinase 4
K04438  CRK, CRKII; C-crk adapter molecule crk
K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04445  RPS6KA5, MSK1; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
K04447  JAK2; Janus kinase 2 [EC:2.7.10.2]
K04448  JUN; transcription factor AP-1
K04451  TP53, P53; tumor protein p53
K04453  MAX; Max protein
K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04462  MECOM, EVI1, PRDM3; [histone H3]-lysine9 N-methyltransferase (ecotropic virus integration site 1 protein) [EC:2.1.1.367]
K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K04469  NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
K04482  RAD51; DNA repair protein RAD51
K04490  TCF7L1; transcription factor 7-like 1
K04491  TCF7L2; transcription factor 7-like 2
K04492  LEF1; lymphoid enhancer-binding factor 1
K04496  CTBP; C-terminal binding protein [EC:1.1.1.428]
K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
K04500  SMAD2; mothers against decapentaplegic homolog 2
K04501  SMAD4; mothers against decapentaplegic homolog 4
K04503  CCND1; G1/S-specific cyclin-D1
K04504  NR1C2, PPARD; peroxisome proliferator-activated receptor delta
K04513  RHOA; Ras homolog gene family, member A
K04514  ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.39]
K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04536  GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537  GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K04538  GNB4; guanine nucleotide-binding protein subunit beta-4
K04539  GNB5; guanine nucleotide-binding protein subunit beta-5
K04540  GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541  GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542  GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543  GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544  GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545  GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546  GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04547  GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548  GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549  GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K04570  BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K04630  GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04632  GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635  GNA11; guanine nucleotide-binding protein subunit alpha-11
K04639  GNA13; guanine nucleotide-binding protein subunit alpha-13
K04662  BMP4; bone morphogenetic protein 4
K04674  TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
K04684  SP1; transcription factor Sp1
K04685  CDKN2B, P15, INK4B; cyclin-dependent kinase inhibitor 2B
K04687  IFNG; interferon gamma
K04688  RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04692  STAT3; signal transducer and activator of transcription 3
K04702  PIM1; proto-oncogene serine/threonine-protein kinase Pim-1 [EC:2.7.11.1]
K04707  CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
K04725  XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K04726  BID; BH3 interacting domain death agonist
K04734  NFKBIA; NF-kappa-B inhibitor alpha
K04735  RELA; transcription factor p65
K04736  IL3; interleukin 3
K04737  IL3RA, CD123; interleukin 3 receptor alpha
K04738  CSF2RB, IL3RB, CD131; cytokine receptor common subunit beta
K05055  IL6R, CD126; interleukin 6 receptor
K05060  IL6ST, GP130, CD130; interleukin 6 signal transducer
K05061  CSF3R, CD114; granulocyte colony-stimulating factor receptor
K05063  IL12RB1, CD212; interleukin 12 receptor beta-1
K05064  IL12RB2; interleukin 12 receptor beta-2
K05065  IL23R; interleukin 23 receptor
K05066  CSF2RA, GMCSFR, CD116; granulocyte-macrophage colony-stimulating factor receptor alpha
K05067  IL5RA, CD125; interleukin 5 receptor alpha
K05068  IL2RA, CD25; interleukin 2 receptor alpha
K05069  IL2RB, CD122; interleukin 2 receptor beta
K05070  IL2RG, CD132; interleukin 2 receptor gamma
K05071  IL4R, CD124; interleukin 4 receptor
K05072  IL7R, CD127; interleukin 7 receptor
K05074  IL15RA, CD215; interleukin 15 receptor alpha
K05076  IL13RA1, CD213A1; interleukin 13 receptor alpha-1
K05079  EPOR; erythropoietin receptor
K05083  ERBB2, HER2, CD340; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K05087  IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K05089  PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05090  CSF1R, FMS, CD115; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K05091  KIT, SCFR, CD117; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K05092  FLT3, FLK2, CD135; fms-related tyrosine kinase 3 [EC:2.7.10.1]
K05093  FGFR2, CD332; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094  FGFR3, CD333; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095  FGFR4, CD334; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K05097  FLT4, VEGFR3; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K05099  MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K05119  ALK, CD246; anaplastic lymphoma kinase [EC:2.7.10.1]
K05126  RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
K05130  IFNAR1; interferon receptor 1
K05131  IFNAR2; interferon receptor 2
K05132  IFNGR1, CD119; interferon gamma receptor 1
K05133  IFNGR2; interferon gamma receptor 2
K05405  IL6; interleukin 6
K05406  IL12A; interleukin 12A
K05414  IFNA; interferon alpha
K05425  IL12B; interleukin 12B
K05426  IL23A; interleukin 23 subunit alpha
K05428  IL5; interleukin 5
K05429  IL2; interleukin 2
K05430  IL4; interleukin 4
K05431  IL7; interleukin 7
K05433  IL15; interleukin 15
K05435  IL13; interleukin 13
K05437  EPO; erythropoietin
K05448  VEGFA; vascular endothelial growth factor A
K05449  VEGFC_D; vascular endothelial growth factor C/D
K05454  FLT3LG; fms-related tyrosine kinase 3 ligand
K05459  IGF1; insulin-like growth factor 1
K05460  HGF; hepatocyte growth factor
K05461  KITLG; KIT ligand
K05635  LAMC1; laminin, gamma 1
K05636  LAMB1; laminin, beta 1
K05637  LAMA1_2; laminin, alpha 1/2
K05638  NFE2L2, NRF2; nuclear factor erythroid 2-related factor 2
K05689  CDH1, CDHE, CD324; cadherin 1, type 1, E-cadherin
K05691  CTNNA; catenin alpha
K05717  FN1; fibronectin 1
K05719  ITGB1, CD29; integrin beta 1
K05725  PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05859  PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K06051  DLL; delta
K06052  JAG1, CD339; jagged-1
K06054  HES1; hairy and enhancer of split 1
K06055  HES5; hairy and enhancer of split 5
K06067  HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K06225  PTCH1; patched 1
K06226  SMO; smoothened
K06229  SUFU; suppressor of fused
K06230  GLI3; zinc finger protein GLI3
K06231  HHIP; hedgehog interacting protein
K06237  COL4A; collagen type IV alpha
K06240  LAMA3_5; laminin, alpha 3/5
K06241  LAMA4; laminin, alpha 4
K06243  LAMB2; laminin, beta 2
K06244  LAMB3; laminin, beta 3
K06245  LAMB4; laminin, beta 4
K06246  LAMC2; laminin, gamma 2
K06247  LAMC3; laminin, gamma 3
K06476  ITGA2B, CD41; integrin alpha 2B
K06481  ITGA2, CD49b; integrin alpha 2
K06482  ITGA3, CD49c; integrin alpha 3
K06485  ITGA6, CD49f; integrin alpha 6
K06487  ITGAV, CD51; integrin alpha V
K06618  RB1; retinoblastoma-associated protein
K06619  ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K06620  E2F3; transcription factor E2F3
K06621  CDKN2A, P16, INK4A; cyclin-dependent kinase inhibitor 2A
K06624  CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
K06625  CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K06626  CCNE; G1/S-specific cyclin-E1
K06627  CCNA; cyclin-A
K06643  MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K06765  DCC; deleted in colorectal carcinoma
K07201  FOXO1; forkhead box protein O1
K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K07299  SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
K07532  ARHGEF12, LARG; Rho guanine nucleotide exchange factor 12
K07825  GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K07826  GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K07827  KRAS, KRAS2; GTPase KRas
K07828  NRAS; GTPase NRas
K07834  RALA; Ras-related protein Ral-A
K07835  RALB; Ras-related protein Ral-B
K07860  RAC2; Ras-related C3 botulinum toxin substrate 2
K07861  RAC3; Ras-related C3 botulinum toxin substrate 3
K08015  RASSF5, RAPL; Ras association domain-containing protein 5
K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K08268  HIF1A; hypoxia-inducible factor 1 alpha
K08367  RUNX1, AML1; runt-related transcription factor 1
K08390  LPAR5, GPR92; lysophosphatidic acid receptor 5
K08524  RXRA, NR2B1; retinoid X receptor alpha
K08525  RXRB, NR2B2; retinoid X receptor beta
K08526  RXRG, NR2B3; retinoid X receptor gamma
K08527  RARA, NR1B1; retinoic acid receptor alpha
K08528  RARB, NR1B2; retinoic acid receptor beta
K08530  NR1C3, PPARG; peroxisome proliferator-activated receptor gamma
K08550  ESR1, NR3A1; estrogen receptor alpha
K08551  ESR2, NR3A2; estrogen receptor beta
K08557  AR, NR3C4; androgen receptor
K08731  BIRC5; baculoviral IAP repeat-containing protein 5
K08732  RALGDS; ral guanine nucleotide dissociation stimulator
K08733  APPL1, DIP13A; DCC-interacting protein 13 alpha
K08734  MLH1; DNA mismatch repair protein MLH1
K08735  MSH2; DNA mismatch repair protein MSH2
K08736  MSH3; DNA mismatch repair protein MSH3
K08737  MSH6; DNA mismatch repair protein MSH6
K08738  CYC; cytochrome c
K08773  RALBP1; RalA-binding protein 1
K08774  TGFA; transforming growth factor, alpha
K08775  BRCA2, FANCD1; breast cancer 2 susceptibility protein
K08803  DAPK; death-associated protein kinase [EC:2.7.11.1]
K08806  PIM2; proto-oncogene serine/threonine-protein kinase Pim-2 [EC:2.7.11.1]
K08845  ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K08878  BCR1, BCR; breakpoint cluster region protein [EC:2.7.11.1]
K09055  CEBPA; CCAAT/enhancer binding protein (C/EBP), alpha
K09091  HEY; hairy and enhancer of split related with YRPW motif
K09095  HIF2A, EPAS1; hypoxia-inducible factor 2 alpha
K09097  ARNT; aryl hydrocarbon receptor nuclear translocator
K09101  NCOA1, SRC1, KAT13A; nuclear receptor coactivator 1 [EC:2.3.1.48]
K09288  CCDC6, PTC; coiled-coil domain-containing protein 6
K09289  NCOA4, PTC3; nuclear receptor coactivator 4
K09290  TPM3; tropomyosin 3
K09291  TPR, MLP1, MLP2; nucleoprotein TPR
K09292  TFG; protein TFG
K09293  PAX8; paired box protein 8
K09348  NKX3-1; homeobox protein Nkx-3.1
K09389  E2F2; transcription factor E2F2
K09438  SPI1; transcription factor PU.1
K09455  MITF; microphthalmia-associated transcription factor
K09487  HSP90B, TRA1; heat shock protein 90kDa beta
K09592  EGLN, HPH; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K09821  AGT, SERPINA8; angiotensinogen
K09848  TRAF4; TNF receptor-associated factor 4
K09849  TRAF5; TNF receptor-associated factor 5
K09850  RASSF1; Ras association domain-containing protein 1
K10030  IL8, CXCL8; interleukin 8
K10031  CXCL12; C-X-C motif chemokine 12
K10053  RUNX1T1, CBFA2T1; CBFA2/RNUX1 translocation partner 1
K10054  PML, TRIM19; E3 SUMO-protein ligase PML [EC:2.3.2.-]
K10055  ZBTB16, PLZF; zinc finger and BTB domain-containing protein 16
K10056  JUP, PG; junction plakoglobin
K10131  PMAIP1, NOXA; phorbol-12-myristate-13-acetate-induced protein 1
K10132  BBC3, PUMA; Bcl-2-binding component 3
K10140  DDB2; DNA damage-binding protein 2
K10151  CCND2; G1/S-specific cyclin-D2
K10152  CCND3; G1/S-specific cyclin-D3
K10456  KLHL19, KEAP1, INRF2; kelch-like protein 19
K10500  ZBTB17, MIZ1; zinc finger and BTB domain-containing protein 17
K11101  PTCH2; patched 2
K11126  TERT, EST2; telomerase reverse transcriptase [EC:2.7.7.49]
K11217  JAK1; Janus kinase 1 [EC:2.7.10.2]
K11218  JAK3; Janus kinase 3 [EC:2.7.10.2]
K11220  STAT1; signal transducer and activator of transcription 1
K11221  STAT2; signal transducer and activator of transcription 2
K11222  STAT4; signal transducer and activator of transcription 4
K11223  STAT5A; signal transducer and activator of transcription 5A
K11224  STAT5B; signal transducer and activator of transcription 5B
K11225  STAT6; signal transducer and activator of transcription 6
K11256  NCOA3, ACTR, KAT13B; nuclear receptor coactivator 3 [EC:2.3.1.48]
K11987  PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K11988  SHH; sonic hedgehog
K12330  ARHGEF1; Rho guanine nucleotide exchange factor 1
K12331  ARHGEF11; Rho guanine nucleotide exchange factor 11
K12361  RASGRP2; RAS guanyl-releasing protein 2
K12362  RASGRP3; RAS guanyl-releasing protein 3
K12363  RASGRP4; RAS guanyl-releasing protein 4
K13241  NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
K13375  TGFB1; transforming growth factor beta-1
K13376  TGFB2; transforming growth factor beta-2
K13377  TGFB3; transforming growth factor beta-3
K13769  IGF2; insulin-like growth factor 2
K14021  BAK, BAK1; Bcl-2 homologous antagonist/killer
K15420  EML4; echinoderm microtubule-associated protein-like 4
K15589  ARNT2; aryl hydrocarbon receptor nuclear translocator 2
K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K16061  BIRC7_8; baculoviral IAP repeat-containing protein 7/8
K16341  BCL2L11, BIM; Bcl-2-like protein 11
K16366  EDN1; endothelin-1
K16797  GLI1; zinc finger protein GLI1
K16798  GLI2; zinc finger protein GLI2
K16858  VEGFB; vascular endothelial growth factor B
K16859  PGF; placenta growth factor
K17386  PDGFB; platelet-derived growth factor subunit B
K17388  ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.39]
K17454  E2F1; transcription factor E2F1
K18496  FGF1; fibroblast growth factor 1
K18497  FGF2; fibroblast growth factor 2
K18806  KIF7; kinesin family member 7
K19464  PLEKHG5; pleckstrin homology domain-containing family G member 5
K19662  PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663  PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K20994  NOTCH2; Notch 2
K20995  NOTCH3; Notch 3
K20996  NOTCH4; Notch 4
K21283  BMP2; bone morphogenetic protein 2
K21635  JAG2; jagged-2
K22182  TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K22183  TERC; telomerase RNA component
K22428  FGF23; fibroblast growth factor 23
K22429  FGF21; fibroblast growth factor 21
K22603  FGF19; fibroblast growth factor 19
K23605  SMAD3; mothers against decapentaplegic homolog 3
K23790  GSTP; glutathione S-transferase P
Compound
C00027  Hydrogen peroxide
C00039  DNA
C00076  Calcium cation
C00122  Fumarate
C00149  (S)-Malate
C00165  Diacylglycerol
C00187  Cholesterol
C00280  Androstenedione
C00410  Progesterone
C00416  Phosphatidate
C00533  Nitric oxide
C00535  Testosterone
C00575  3',5'-Cyclic AMP
C00584  Prostaglandin E2
C00681  1-Acyl-sn-glycerol 3-phosphate
C00704  Superoxide
C00735  Cortisol
C00762  Cortisone
C00777  Retinoate
C00951  Estradiol-17beta
C01227  Dehydroepiandrosterone
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01471  Acrolein
C03917  Dihydrotestosterone
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C07653  Flutamide
C15493  9-cis-Retinoic acid
C16038  2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
C16844  Hydroxyl radical
C21641  Hydroperoxyl radical
C21642  4-Hydroxynonenal
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ko04020  Calcium signaling pathway
ko04024  cAMP signaling pathway
ko04060  Cytokine-cytokine receptor interaction
ko04066  HIF-1 signaling pathway
ko04110  Cell cycle
ko04115  p53 signaling pathway
ko04150  mTOR signaling pathway
ko04151  PI3K-Akt signaling pathway
ko04210  Apoptosis
ko04310  Wnt signaling pathway
ko04330  Notch signaling pathway
ko04340  Hedgehog signaling pathway
ko04350  TGF-beta signaling pathway
ko04370  VEGF signaling pathway
ko04510  Focal adhesion
ko04512  ECM-receptor interaction
ko04520  Adherens junction
ko04630  JAK-STAT signaling pathway
ko04915  Estrogen signaling pathway

DBGET integrated database retrieval system