KEGG   PATHWAY: panu05200
Entry
panu05200                   Pathway                                
Name
Pathways in cancer - Papio anubis (olive baboon)
Class
Human Diseases; Cancer: overview
Pathway map
panu05200  Pathways in cancer
panu05200

Organism
Papio anubis (olive baboon) [GN:panu]
Gene
101024199  DCC; netrin receptor DCC isoform X1 [KO:K06765]
101023728  CASP3; caspase-3 isoform X2 [KO:K02187] [EC:3.4.22.56]
101009907  CASP9; caspase-9 isoform X1 [KO:K04399] [EC:3.4.22.62]
101021089  APPL1; DCC-interacting protein 13-alpha isoform X1 [KO:K08733]
101005609  CDH1; cadherin-1 isoform X1 [KO:K05689]
101014712  CTNNB1; catenin beta-1 isoform X1 [KO:K02105]
101021030  CTNNA1; catenin alpha-1 isoform X2 [KO:K05691]
101010501  CTNNA3; catenin alpha-3 isoform X2 [KO:K05691]
101010650  CTNNA2; catenin alpha-2 isoform X1 [KO:K05691]
101012942  AXIN2; axin-2 isoform X1 [KO:K04385]
101015820  APC; adenomatous polyposis coli protein isoform X7 [KO:K02085]
100998800  GSK3B; glycogen synthase kinase-3 beta isoform X1 [KO:K03083] [EC:2.7.11.26]
101024089  TCF7; LOW QUALITY PROTEIN: transcription factor 7 [KO:K02620]
101017547  TCF7L1; transcription factor 7-like 1 [KO:K04490]
101026705  TCF7L2; transcription factor 7-like 2 isoform X20 [KO:K04491]
101017352  LEF1; lymphoid enhancer-binding factor 1 isoform X2 [KO:K04492]
101006161  BIRC5; baculoviral IAP repeat-containing protein 5 [KO:K08731]
101000645  MYC; myc proto-oncogene protein [KO:K04377]
101019923  CCND1; G1/S-specific cyclin-D1 [KO:K04503]
101013629  WNT1; proto-oncogene Wnt-1 [KO:K03209]
101008897  WNT2B; protein Wnt-2b [KO:K00182]
100126674  WNT2; protein Wnt-2 precursor [KO:K00182]
101001727  WNT3; proto-oncogene Wnt-3 isoform X2 [KO:K00312]
101005424  WNT4; protein Wnt-4 [KO:K00408]
100997755  WNT5A; protein Wnt-5a isoform X2 [KO:K00444]
101019776  WNT5B; protein Wnt-5b [KO:K00444]
100997506  WNT6; protein Wnt-6 [KO:K00445]
101009898  WNT7B; protein Wnt-7b [KO:K00572]
101002180  WNT7A; protein Wnt-7a isoform X1 [KO:K00572]
101014279  WNT8A; protein Wnt-8a [KO:K00714]
101002037  WNT8B; protein Wnt-8b [KO:K00714]
100999626  WNT9A; protein Wnt-9a isoform X2 [KO:K01064]
101007522  WNT9B; protein Wnt-9b [KO:K01064]
100997855  WNT10A; protein Wnt-10a [KO:K01357]
101013252  WNT10B; protein Wnt-10b [KO:K01357]
101005798  WNT11; protein Wnt-11 [KO:K01384]
101022538  WNT16; protein Wnt-16 isoform X1 [KO:K01558]
101015632  FZD7; frizzled-7 [KO:K02432]
100137461  FZD1; frizzled-1 [KO:K02432]
101011059  FZD2; frizzled-2 [KO:K02235]
101000744  FZD3; frizzled-3 isoform X1 [KO:K02329]
101013533  FZD4; frizzled-4 isoform X1 [KO:K02354]
101013139  FZD5; frizzled-5 [KO:K02375]
101012990  FZD8; LOW QUALITY PROTEIN: frizzled-8 [KO:K02375]
100999712  FZD6; frizzled-6 [KO:K02376]
101004836  FZD10; frizzled-10 [KO:K02842]
101010325  FZD9; frizzled-9 [KO:K02842]
101026239  LRP6; low-density lipoprotein receptor-related protein 6 [KO:K03068]
100189542  LRP5; low-density lipoprotein receptor-related protein 5 precursor [KO:K03068]
101019485  DVL2; LOW QUALITY PROTEIN: segment polarity protein dishevelled homolog DVL-2 [KO:K02353]
101007736  DVL3; segment polarity protein dishevelled homolog DVL-3 isoform X6 [KO:K02353]
101007009  DVL1; LOW QUALITY PROTEIN: segment polarity protein dishevelled homolog DVL-1 [KO:K02353]
101009787  FRAT1; proto-oncogene FRAT1 [KO:K03069]
101013482  FRAT2; GSK-3-binding protein FRAT2 [KO:K03096]
101003685  F2; prothrombin [KO:K01313] [EC:3.4.21.5]
101013870  AGT; angiotensinogen isoform X2 [KO:K09821]
101014878  F2R; proteinase-activated receptor 1 [KO:K03914]
101023014  F2RL3; proteinase-activated receptor 4 [KO:K04236]
101008582  LPAR1; lysophosphatidic acid receptor 1 isoform X1 [KO:K04289]
101002801  LPAR2; LOW QUALITY PROTEIN: lysophosphatidic acid receptor 2 [KO:K04291]
101001691  LPAR3; lysophosphatidic acid receptor 3 [KO:K04294]
101018216  LPAR4; lysophosphatidic acid receptor 4 [KO:K04275]
101020371  LPAR5; lysophosphatidic acid receptor 5 [KO:K08390]
101017943  LPAR6; lysophosphatidic acid receptor 6 [KO:K04273]
101003219  AGTR1; type-1 angiotensin II receptor [KO:K04166]
101015317  GNA12; guanine nucleotide-binding protein subunit alpha-12 isoform X1 [KO:K04346]
101010815  GNA13; guanine nucleotide-binding protein subunit alpha-13 isoform X1 [KO:K04639]
101013535  ARHGEF12; rho guanine nucleotide exchange factor 12 isoform X1 [KO:K07532]
101014697  ARHGEF11; rho guanine nucleotide exchange factor 11 isoform X1 [KO:K12331]
101013796  ARHGEF1; rho guanine nucleotide exchange factor 1 isoform X5 [KO:K12330]
101013129  PLEKHG5; pleckstrin homology domain-containing family G member 5 isoform X1 [KO:K19464]
101023586  RHOA; transforming protein RhoA isoform X1 [KO:K04513]
100997671  ROCK1; rho-associated protein kinase 1 isoform X2 [KO:K04514] [EC:2.7.11.1]
101003099  ROCK2; rho-associated protein kinase 2 isoform X5 [KO:K17388] [EC:2.7.11.1]
101001096  stromal cell-derived factor 1 isoform X2 [KO:K10031]
100126711  CXCR4; C-X-C chemokine receptor type 4 [KO:K04189]
101011013  GNAI3; guanine nucleotide-binding protein G(i) subunit alpha [KO:K04630]
101011251  GNAI2; guanine nucleotide-binding protein G(i) subunit alpha-2 isoform X1 [KO:K04630]
101020528  GNAI1; guanine nucleotide-binding protein G(i) subunit alpha-1 isoform X1 [KO:K04630]
101025136  PTGER1; prostaglandin E2 receptor EP1 subtype [KO:K04258]
101014300  PTGER2; prostaglandin E2 receptor EP2 subtype isoform X2 [KO:K04259]
101025901  PTGER3; prostaglandin E2 receptor EP3 subtype isoform X2 [KO:K04260]
101013075  PTGER4; prostaglandin E2 receptor EP4 subtype isoform X1 [KO:K04261]
103887915  neuroendocrine secretory protein 55 [KO:K04632]
101006785  guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas isoform X2 [KO:K04632]
100998237  ADCY1; adenylate cyclase type 1 [KO:K08041] [EC:4.6.1.1]
101006754  ADCY2; adenylate cyclase type 2 isoform X1 [KO:K08042] [EC:4.6.1.1]
101006469  ADCY3; adenylate cyclase type 3 isoform X1 [KO:K08043] [EC:4.6.1.1]
101021139  ADCY4; adenylate cyclase type 4 isoform X1 [KO:K08044] [EC:4.6.1.1]
101014828  ADCY5; adenylate cyclase type 5 [KO:K08045] [EC:4.6.1.1]
101008785  ADCY6; adenylate cyclase type 6 isoform X3 [KO:K08046] [EC:4.6.1.1]
101000833  ADCY7; adenylate cyclase type 7 isoform X1 [KO:K08047] [EC:4.6.1.1]
101007115  ADCY8; adenylate cyclase type 8 isoform X3 [KO:K08048] [EC:4.6.1.1]
101004325  ADCY9; adenylate cyclase type 9 isoform X2 [KO:K08049] [EC:4.6.1.1]
101026251  PRKACB; cAMP-dependent protein kinase catalytic subunit beta isoform X15 [KO:K04345] [EC:2.7.11.11]
101026282  PRKACG; cAMP-dependent protein kinase catalytic subunit gamma [KO:K04345] [EC:2.7.11.11]
101020553  PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X2 [KO:K04345] [EC:2.7.11.11]
101016713  GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 isoform X1 [KO:K04536]
101017982  GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 [KO:K04537]
100997846  GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 [KO:K07825]
101003812  GNB4; guanine nucleotide-binding protein subunit beta-4 isoform X1 [KO:K04538]
101004338  GNB5; guanine nucleotide-binding protein subunit beta-5 [KO:K04539]
116275838  guanine nucleotide-binding protein subunit beta-5-like [KO:K04539]
101011441  GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 [KO:K07826]
101009143  GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 [KO:K04540]
101024158  GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 [KO:K04541]
100997854  GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 [KO:K04542]
101000991  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 [KO:K04542]
101012463  GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 [KO:K04543]
108583299  GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 [KO:K04544]
101004170  GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 [KO:K04545]
101006936  GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 [KO:K04546]
101015176  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 [KO:K04347]
101008105  GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1 [KO:K04548]
101021341  GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 [KO:K04549]
101000665  COL4A3; collagen alpha-3(IV) chain isoform X1 [KO:K06237]
101000307  COL4A4; collagen alpha-4(IV) chain [KO:K06237]
101026688  COL4A5; collagen alpha-5(IV) chain isoform X1 [KO:K06237]
101011877  COL4A2; collagen alpha-2(IV) chain [KO:K06237]
101024690  COL4A6; collagen alpha-6(IV) chain isoform X2 [KO:K06237]
101011528  COL4A1; collagen alpha-1(IV) chain isoform X1 [KO:K06237]
101009064  LAMA2; laminin subunit alpha-2 isoform X1 [KO:K05637]
101005361  LAMA1; laminin subunit alpha-1 isoform X1 [KO:K05637]
116272742  laminin subunit alpha-1-like isoform X1 [KO:K05637]
101024356  LAMA5; laminin subunit alpha-5 [KO:K06240]
101009063  LAMA3; laminin subunit alpha-3 isoform X5 [KO:K06240]
101002096  LAMA4; laminin subunit alpha-4 isoform X1 [KO:K06241]
101025814  LAMB1; LOW QUALITY PROTEIN: laminin subunit beta-1 [KO:K05636]
101000787  LAMB2; laminin subunit beta-2 [KO:K06243]
101005084  LAMB3; laminin subunit beta-3 isoform X1 [KO:K06244]
101026514  LAMB4; laminin subunit beta-4 [KO:K06245]
101008905  LAMC1; laminin subunit gamma-1 isoform X1 [KO:K05635]
101007972  LAMC2; laminin subunit gamma-2 [KO:K06246]
101006376  LAMC3; laminin subunit gamma-3 [KO:K06247]
101004025  FN1; fibronectin isoform X9 [KO:K05717]
101014159  ITGA2; integrin alpha-2 [KO:K06481]
101009395  ITGA2B; integrin alpha-IIb [KO:K06476]
116271056  integrin alpha-3-like isoform X1 [KO:K06482]
116271057  integrin alpha-3-like [KO:K06482]
101003243  integrin alpha-3 isoform X2 [KO:K06482]
100999739  ITGA6; integrin alpha-6 isoform X1 [KO:K06485]
101017655  ITGAV; integrin alpha-V isoform X1 [KO:K06487]
101005052  ITGB1; integrin beta-1 isoform X2 [KO:K05719]
101022936  PTK2; focal adhesion kinase 1 isoform X25 [KO:K05725] [EC:2.7.10.2]
101004976  PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
101008699  PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
101002278  PIK3CD; LOW QUALITY PROTEIN: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform [KO:K00922] [EC:2.7.1.153]
100510873  PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X4 [KO:K02649]
101009981  PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta [KO:K02649]
101002971  PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1 [KO:K02649]
101016586  PTEN; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X1 [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
101007449  NKX3-1; homeobox protein Nkx-3.1 [KO:K09348]
100997634  AKT3; RAC-gamma serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
101000402  AKT1; RAC-alpha serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
100381179  AKT2; RAC-beta serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
100998877  CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1 [KO:K04467] [EC:2.7.11.10]
101016447  IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta isoform X5 [KO:K07209] [EC:2.7.11.10]
101023751  NFKBIA; NF-kappa-B inhibitor alpha [KO:K04734]
101026781  NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X6 [KO:K02580]
101020366  NFKB2; nuclear factor NF-kappa-B p100 subunit isoform X4 [KO:K04469]
101017078  RELA; transcription factor p65 isoform X1 [KO:K04735]
101025796  PTGS2; prostaglandin G/H synthase 2 [KO:K11987] [EC:1.14.99.1]
101019718  nitric oxide synthase, inducible [KO:K13241] [EC:1.14.13.39]
101026183  BCL2; apoptosis regulator Bcl-2 isoform X3 [KO:K02161]
101026503  BIRC2; baculoviral IAP repeat-containing protein 2 isoform X2 [KO:K16060]
100997299  BIRC3; baculoviral IAP repeat-containing protein 3 isoform X1 [KO:K16060]
100998457  LOW QUALITY PROTEIN: baculoviral IAP repeat-containing protein 8 [KO:K04725] [EC:2.3.2.27]
101022825  XIAP; E3 ubiquitin-protein ligase XIAP [KO:K04725] [EC:2.3.2.27]
101016461  BIRC7; baculoviral IAP repeat-containing protein 7 [KO:K16061]
101019436  BCL2L1; bcl-2-like protein 1 isoform X1 [KO:K04570]
101001256  TRAF1; TNF receptor-associated factor 1 [KO:K03172]
101017914  TRAF2; LOW QUALITY PROTEIN: TNF receptor-associated factor 2 [KO:K03173] [EC:2.3.2.27]
101015482  TRAF3; TNF receptor-associated factor 3 isoform X1 [KO:K03174]
101012840  TNF receptor-associated factor 4-like [KO:K09848]
100998010  TRAF4; TNF receptor-associated factor 4 [KO:K09848]
101024624  TRAF5; TNF receptor-associated factor 5 isoform X4 [KO:K09849]
101002649  TRAF6; TNF receptor-associated factor 6 [KO:K03175] [EC:2.3.2.27]
101015041  MTOR; serine/threonine-protein kinase mTOR isoform X2 [KO:K07203] [EC:2.7.11.1]
101012071  RPS6KB2; ribosomal protein S6 kinase beta-2 isoform X1 [KO:K04688] [EC:2.7.11.1]
101024761  RPS6KB1; ribosomal protein S6 kinase beta-1 isoform X1 [KO:K04688] [EC:2.7.11.1]
101012551  BAD; bcl2-associated agonist of cell death [KO:K02158]
101017109  FOXO1; forkhead box protein O1 [KO:K07201]
101016712  MDM2; E3 ubiquitin-protein ligase Mdm2 isoform X1 [KO:K06643] [EC:2.3.2.27]
101006608  TP53; cellular tumor antigen p53 [KO:K04451]
101001461  CDKN1B; cyclin-dependent kinase inhibitor 1B [KO:K06624]
100999911  CDKN1A; cyclin-dependent kinase inhibitor 1 [KO:K06625]
101017283  BCR; breakpoint cluster region protein isoform X1 [KO:K08878] [EC:2.7.11.1]
101007628  ABL1; tyrosine-protein kinase ABL1 isoform X1 [KO:K06619] [EC:2.7.10.2]
101007122  CRKL; crk-like protein [KO:K04438]
101011160  CRK; adapter molecule crk isoform X1 [KO:K04438]
101005565  CBL; E3 ubiquitin-protein ligase CBL isoform X1 [KO:K04707] [EC:2.3.2.27]
100998364  signal transducer and activator of transcription 5A isoform X1 [KO:K11223]
101000002  STAT5B; signal transducer and activator of transcription 5B isoform X1 [KO:K11224]
101006850  PIM1; serine/threonine-protein kinase pim-1 [KO:K04702] [EC:2.7.11.1]
101012133  PIM2; serine/threonine-protein kinase pim-2 isoform X1 [KO:K08806] [EC:2.7.11.1]
101012078  KNG1; kininogen-1 isoform X2 [KO:K03898]
100999182  EDN1; endothelin-1 [KO:K16366]
101014902  BDKRB1; B1 bradykinin receptor [KO:K03915]
101014305  BDKRB2; B2 bradykinin receptor [KO:K03916]
101024428  EDNRA; endothelin-1 receptor [KO:K04197]
101012814  EDNRB; endothelin receptor type B [KO:K04198]
101024177  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha isoform X2 [KO:K04634]
101019734  GNA11; guanine nucleotide-binding protein subunit alpha-11 isoform X1 [KO:K04635]
101012903  PLCB3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 [KO:K05858] [EC:3.1.4.11]
100998763  PLCB1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X1 [KO:K05858] [EC:3.1.4.11]
100999120  PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X5 [KO:K05858] [EC:3.1.4.11]
101010000  PLCB2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X4 [KO:K05858] [EC:3.1.4.11]
101016532  PRKCA; protein kinase C alpha type isoform X4 [KO:K02677] [EC:2.7.11.13]
101009865  PRKCB; protein kinase C beta type isoform X1 [KO:K19662] [EC:2.7.11.13]
100137333  PRKCG; protein kinase C gamma type [KO:K19663] [EC:2.7.11.13]
100126754  IL2; interleukin-2 precursor [KO:K05429]
100137199  IL3; interleukin-3 precursor [KO:K04736]
100126747  IL4; interleukin-4 precursor [KO:K05430]
100137220  IL5; interleukin-5 [KO:K05428]
100381195  IL6; interleukin-6 precursor [KO:K05405]
101004703  IL7; interleukin-7 isoform X1 [KO:K05431]
100126719  IL12A; interleukin-12 subunit alpha precursor [KO:K05406]
100126717  IL12B; interleukin-12 subunit beta precursor [KO:K05425]
100137221  IL13; interleukin-13 precursor [KO:K05435]
101006955  IL15; interleukin-15 isoform X2 [KO:K05433]
101011696  IL23A; interleukin-23 subunit alpha isoform X2 [KO:K05426]
101013171  EPO; erythropoietin [KO:K05437]
101023828  LOW QUALITY PROTEIN: interferon alpha-21 [KO:K05414]
101016516  interferon alpha-1/13 [KO:K05414]
116270026  interferon alpha-1/13 [KO:K05414]
101019008  LOW QUALITY PROTEIN: interferon alpha-1/13 [KO:K05414]
101018652  LOW QUALITY PROTEIN: interferon alpha-1/13 [KO:K05414]
101017918  interferon alpha-8 [KO:K05414]
101018287  interferon alpha-2 [KO:K05414]
101019380  interferon alpha-6 [KO:K05414]
101021706  interferon alpha-14 [KO:K05414]
101023118  interferon alpha-4 [KO:K05414]
100126724  IFNG; interferon gamma precursor [KO:K04687]
101004576  IL2RA; interleukin-2 receptor subunit alpha isoform X3 [KO:K05068]
101014683  IL2RB; interleukin-2 receptor subunit beta isoform X4 [KO:K05069]
101008968  IL2RG; cytokine receptor common subunit gamma [KO:K05070]
101000289  LOW QUALITY PROTEIN: interleukin-3 receptor subunit alpha-like [KO:K04737]
101022672  IL4R; interleukin-4 receptor subunit alpha isoform X4 [KO:K05071]
101009794  CSF2RB; cytokine receptor common subunit beta isoform X1 [KO:K04738]
101024506  IL5RA; interleukin-5 receptor subunit alpha [KO:K05067]
101024850  IL6R; interleukin-6 receptor subunit alpha [KO:K05055]
100998383  IL6ST; interleukin-6 receptor subunit beta isoform X1 [KO:K05060]
100997339  IL7R; interleukin-7 receptor subunit alpha [KO:K05072]
101015690  IL12RB1; interleukin-12 receptor subunit beta-1 isoform X8 [KO:K05063]
101012647  IL12RB2; interleukin-12 receptor subunit beta-2 [KO:K05064]
101026802  IL13RA1; interleukin-13 receptor subunit alpha-1 isoform X1 [KO:K05076]
101003876  IL15RA; interleukin-15 receptor subunit alpha [KO:K05074]
101011937  IL23R; interleukin-23 receptor [KO:K05065]
101008944  EPOR; erythropoietin receptor [KO:K05079]
100137245  IFNAR1; interferon alpha/beta receptor 1 [KO:K05130]
100137545  IFNAR2; interferon alpha/beta receptor 2 precursor [KO:K05131]
101000704  IFNGR1; interferon gamma receptor 1 isoform X1 [KO:K05132]
100137246  IFNGR2; interferon gamma receptor 2 precursor [KO:K05133]
101004149  EML4; echinoderm microtubule-associated protein-like 4 isoform X5 [KO:K15420]
101020267  ALK; ALK tyrosine kinase receptor isoform X2 [KO:K05119] [EC:2.7.10.1]
101004206  RASGRP1; RAS guanyl-releasing protein 1 isoform X1 [KO:K04350]
100137599  RASGRP2; RAS guanyl-releasing protein 2 [KO:K12361]
101001477  RASGRP3; ras guanyl-releasing protein 3 isoform X1 [KO:K12362]
101023506  RASGRP4; RAS guanyl-releasing protein 4 [KO:K12363]
101002872  JAK1; tyrosine-protein kinase JAK1 isoform X1 [KO:K11217] [EC:2.7.10.2]
101007171  JAK2; tyrosine-protein kinase JAK2 isoform X4 [KO:K04447] [EC:2.7.10.2]
101014985  JAK3; tyrosine-protein kinase JAK3 isoform X1 [KO:K11218] [EC:2.7.10.2]
100998929  STAT3; signal transducer and activator of transcription 3 isoform X9 [KO:K04692]
101005886  STAT1; signal transducer and activator of transcription 1-alpha/beta [KO:K11220]
101011342  STAT2; LOW QUALITY PROTEIN: signal transducer and activator of transcription 2 [KO:K11221]
101007479  STAT4; signal transducer and activator of transcription 4 isoform X1 [KO:K11222]
101023204  STAT6; signal transducer and activator of transcription 6 isoform X1 [KO:K11225]
100510872  VEGFA; vascular endothelial growth factor A isoform X1 [KO:K05448]
101014707  VEGFB; vascular endothelial growth factor B isoform X1 [KO:K16858]
101018226  PGF; placenta growth factor isoform X1 [KO:K16859]
101009639  VEGFC; vascular endothelial growth factor C [KO:K05449]
101002360  VEGFD; vascular endothelial growth factor D isoform X1 [KO:K05449]
101023802  TGFA; protransforming growth factor alpha isoform X1 [KO:K08774]
101026665  EGF; LOW QUALITY PROTEIN: pro-epidermal growth factor [KO:K04357]
101003588  EGFR; epidermal growth factor receptor isoform X1 [KO:K04361] [EC:2.7.10.1]
101007278  ERBB2; receptor tyrosine-protein kinase erbB-2 isoform X1 [KO:K05083] [EC:2.7.10.1]
100998521  PDGFA; platelet-derived growth factor subunit A isoform X2 [KO:K04359]
101010999  PDGFB; platelet-derived growth factor subunit B [KO:K17386]
101022081  PDGFRA; platelet-derived growth factor receptor alpha [KO:K04363] [EC:2.7.10.1]
101008264  PDGFRB; platelet-derived growth factor receptor beta [KO:K05089] [EC:2.7.10.1]
101010276  IGF1; insulin-like growth factor I isoform X2 [KO:K05459]
100137527  IGF2; insulin-like growth factor II precursor [KO:K13769]
100126735  IGF1R; insulin-like growth factor 1 receptor isoform X1 [KO:K05087] [EC:2.7.10.1]
101011930  KITLG; kit ligand isoform X1 [KO:K05461]
101021734  KIT; mast/stem cell growth factor receptor Kit isoform X5 [KO:K05091] [EC:2.7.10.1]
101007432  FLT3LG; fms-related tyrosine kinase 3 ligand isoform X6 [KO:K05454]
101004066  FLT3; receptor-type tyrosine-protein kinase FLT3 isoform X1 [KO:K05092] [EC:2.7.10.1]
101018541  HGF; hepatocyte growth factor isoform X1 [KO:K05460]
100126669  MET; hepatocyte growth factor receptor precursor [KO:K05099] [EC:2.7.10.1]
100137595  FGF1; fibroblast growth factor 1 [KO:K18496]
101003965  FGF2; fibroblast growth factor 2 isoform X1 [KO:K18497]
101005767  FGF6; fibroblast growth factor 6 [KO:K04358]
116269385  FGF8; fibroblast growth factor 8 [KO:K04358]
101018520  FGF3; fibroblast growth factor 3 [KO:K04358]
101019224  FGF4; fibroblast growth factor 4 [KO:K04358]
101006530  FGF10; fibroblast growth factor 10 [KO:K04358]
101024074  FGF5; fibroblast growth factor 5 isoform X1 [KO:K04358]
101022229  FGF17; fibroblast growth factor 17 [KO:K04358]
101022673  FGF18; fibroblast growth factor 18 [KO:K04358]
101011173  FGF9; fibroblast growth factor 9 [KO:K04358]
101019167  fibroblast growth factor 7 [KO:K04358]
101003408  FGF20; fibroblast growth factor 20 [KO:K04358]
116275849  fibroblast growth factor 7 [KO:K04358]
101012136  FGF16; fibroblast growth factor 16 [KO:K04358]
101019568  FGF19; fibroblast growth factor 19 [KO:K22603]
101005414  FGF23; fibroblast growth factor 23 [KO:K22428]
101002603  FGFR1; fibroblast growth factor receptor 1 isoform X6 [KO:K04362] [EC:2.7.10.1]
101002495  FGFR2; fibroblast growth factor receptor 2 isoform X12 [KO:K05093] [EC:2.7.10.1]
101014560  FGFR3; fibroblast growth factor receptor 3 isoform X1 [KO:K05094] [EC:2.7.10.1]
101025157  FGFR4; LOW QUALITY PROTEIN: fibroblast growth factor receptor 4 [KO:K05095] [EC:2.7.10.1]
101002675  GRB2; growth factor receptor-bound protein 2 [KO:K04364]
101022024  SOS1; son of sevenless homolog 1 isoform X1 [KO:K03099]
101003749  SOS2; son of sevenless homolog 2 isoform X1 [KO:K03099]
101002992  HRAS; GTPase HRas isoform X2 [KO:K02833]
101017528  KRAS; GTPase KRas isoform X2 [KO:K07827]
101026253  NRAS; GTPase NRas isoform X2 [KO:K07828]
101019640  ARAF; serine/threonine-protein kinase A-Raf [KO:K08845] [EC:2.7.11.1]
101022780  BRAF; serine/threonine-protein kinase B-raf isoform X1 [KO:K04365] [EC:2.7.11.1]
101009029  RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X1 [KO:K04366] [EC:2.7.11.1]
101008394  MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 isoform X1 [KO:K04368] [EC:2.7.12.2]
101004074  MAP2K2; dual specificity mitogen-activated protein kinase kinase 2 isoform X1 [KO:K04369] [EC:2.7.12.2]
101012041  MAPK1; mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
101006756  MAPK3; mitogen-activated protein kinase 3 isoform X1 [KO:K04371] [EC:2.7.11.24]
101010894  JUN; transcription factor AP-1 [KO:K04448]
101021141  FOS; proto-oncogene c-Fos isoform X1 [KO:K04379]
101000568  ETS1; protein C-ets-1 isoform X1 [KO:K02678]
101000222  MMP1; interstitial collagenase [KO:K01388] [EC:3.4.24.7]
101014166  MMP2; 72 kDa type IV collagenase [KO:K01398] [EC:3.4.24.24]
101003884  MMP9; matrix metalloproteinase-9 [KO:K01403] [EC:3.4.24.35]
100381196  CXCL8; interleukin-8 precursor [KO:K10030]
101011004  CDK4; cyclin-dependent kinase 4 [KO:K02089] [EC:2.7.11.22]
101012148  RPS6KA5; ribosomal protein S6 kinase alpha-5 isoform X1 [KO:K04445] [EC:2.7.11.1]
101019433  RET; proto-oncogene tyrosine-protein kinase receptor Ret [KO:K05126] [EC:2.7.10.1]
101027056  CCDC6; coiled-coil domain-containing protein 6 [KO:K09288]
101010389  NCOA4; nuclear receptor coactivator 4 isoform X2 [KO:K09289]
101012772  NTRK1; high affinity nerve growth factor receptor isoform X1 [KO:K03176] [EC:2.7.10.1]
101022375  TPM3; tropomyosin alpha-3 chain isoform X17 [KO:K09290]
101026855  TPR; nucleoprotein TPR isoform X1 [KO:K09291]
101000213  TFG; protein TFG isoform X1 [KO:K09292]
101006593  RASSF1; ras association domain-containing protein 1 isoform X2 [KO:K09850]
101026375  RASSF5; ras association domain-containing protein 5 isoform X1 [KO:K08015]
100137163  STK4; serine/threonine-protein kinase 4 [KO:K04411]
101016019  DAPK1; death-associated protein kinase 1 isoform X1 [KO:K08803] [EC:2.7.11.1]
101000600  DAPK3; LOW QUALITY PROTEIN: death-associated protein kinase 3 [KO:K08803] [EC:2.7.11.1]
101021037  DAPK2; death-associated protein kinase 2 isoform X4 [KO:K08803] [EC:2.7.11.1]
101012165  PLCG1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X2 [KO:K01116] [EC:3.1.4.11]
101004091  PLCG2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 isoform X1 [KO:K05859] [EC:3.1.4.11]
101021974  ELK1; ETS domain-containing protein Elk-1 [KO:K04375]
101017532  CALML6; calmodulin-like protein 6 [KO:K02183]
100997835  CALML5; calmodulin-like protein 5 [KO:K02183]
100997036  CALM2; calmodulin-2 [KO:K02183]
101019754  CALML4; LOW QUALITY PROTEIN: calmodulin-like protein 4 [KO:K02183]
101007101  CALM1; calmodulin-1 isoform X1 [KO:K02183]
101011767  CALM3; calmodulin-3 isoform X2 [KO:K02183]
100998530  CALML3; calmodulin-like protein 3 [KO:K02183]
116269450  calcium/calmodulin-dependent protein kinase type II subunit gamma-like isoform X1 [KO:K04515] [EC:2.7.11.17]
116269451  calcium/calmodulin-dependent protein kinase type II subunit gamma-like isoform X1 [KO:K04515] [EC:2.7.11.17]
101008925  CAMK2B; calcium/calmodulin-dependent protein kinase type II subunit beta isoform X10 [KO:K04515] [EC:2.7.11.17]
101009984  CAMK2D; calcium/calmodulin-dependent protein kinase type II subunit delta isoform X37 [KO:K04515] [EC:2.7.11.17]
101011087  CAMK2A; calcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1 [KO:K04515] [EC:2.7.11.17]
101019885  CAMK2G; calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X18 [KO:K04515] [EC:2.7.11.17]
101006888  RALGDS; ral guanine nucleotide dissociation stimulator isoform X4 [KO:K08732]
100997587  LOW QUALITY PROTEIN: ral-GDS-related protein-like [KO:K08732]
100997883  RALA; ras-related protein Ral-A [KO:K07834]
101018519  RALB; ras-related protein Ral-B isoform X1 [KO:K07835]
101025607  RALBP1; ralA-binding protein 1 [KO:K08773]
101004833  CDC42; cell division control protein 42 homolog isoform X1 [KO:K04393]
101003935  RAC1; ras-related C3 botulinum toxin substrate 1 isoform X1 [KO:K04392]
101016465  RAC2; ras-related C3 botulinum toxin substrate 2 isoform X1 [KO:K07860]
101011983  RAC3; ras-related C3 botulinum toxin substrate 3 isoform X2 [KO:K07861]
101018997  PLD1; phospholipase D1 isoform X1 [KO:K01115] [EC:3.1.4.4]
101017925  PLD2; phospholipase D2 isoform X2 [KO:K01115] [EC:3.1.4.4]
101005010  MAPK10; mitogen-activated protein kinase 10 isoform X3 [KO:K04440] [EC:2.7.11.24]
101022320  MAPK9; mitogen-activated protein kinase 9 isoform X1 [KO:K04440] [EC:2.7.11.24]
101019884  MAPK8; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
101026378  PAX8; paired box protein Pax-8 isoform X2 [KO:K09293]
101012073  PPARG; peroxisome proliferator-activated receptor gamma isoform X1 [KO:K08530]
101012079  RXRA; retinoic acid receptor RXR-alpha isoform X3 [KO:K08524]
101021005  RXRB; retinoic acid receptor RXR-beta isoform X2 [KO:K08525]
101015058  RXRG; retinoic acid receptor RXR-gamma isoform X1 [KO:K08526]
101010670  RARB; retinoic acid receptor beta isoform X2 [KO:K08528]
100303417  ESR1; estrogen receptor [KO:K08550]
100303418  ESR2; estrogen receptor beta [KO:K08551]
101007720  NCOA1; nuclear receptor coactivator 1 isoform X1 [KO:K09101] [EC:2.3.1.48]
101022945  NCOA3; nuclear receptor coactivator 3 isoform X1 [KO:K11256] [EC:2.3.1.48]
116268873  SP1; transcription factor Sp1 isoform X1 [KO:K04684]
101015561  PPARD; peroxisome proliferator-activated receptor delta [KO:K04504]
101026167  JUP; junction plakoglobin [KO:K10056]
101023686  ZBTB16; zinc finger and BTB domain-containing protein 16 [KO:K10055]
101019389  RARA; retinoic acid receptor alpha isoform X2 [KO:K08527]
100999197  CCNA2; cyclin-A2 [KO:K06627]
101003474  CCNA1; cyclin-A1 isoform X1 [KO:K06627]
101019999  PML; protein PML isoform X4 [KO:K10054] [EC:2.3.2.-]
101020650  RUNX1; runt-related transcription factor 1 isoform X1 [KO:K08367]
101012986  RUNX1T1; protein CBFA2T1 isoform X6 [KO:K10053]
101023581  SPI1; transcription factor PU.1 isoform X4 [KO:K09438]
101014747  CEBPA; CCAAT/enhancer-binding protein alpha [KO:K09055]
101012178  CSF3R; granulocyte colony-stimulating factor receptor isoform X1 [KO:K05061]
101008957  CSF1R; macrophage colony-stimulating factor 1 receptor [KO:K05090] [EC:2.7.10.1]
101017208  cyclin-dependent kinase inhibitor 2A isoform X2 [KO:K06621]
101015078  tumor suppressor ARF-like [KO:K06621]
101000533  E2F1; transcription factor E2F1 [KO:K17454]
101015623  E2F2; transcription factor E2F2 isoform X1 [KO:K09389]
101025116  E2F3; transcription factor E2F3 isoform X3 [KO:K06620]
101016934  MAX; protein max isoform X5 [KO:K04453]
101014210  ZBTB17; zinc finger and BTB domain-containing protein 17 isoform X4 [KO:K10500]
101014127  CDKN2B; cyclin-dependent kinase 4 inhibitor B [KO:K04685]
101013902  CDK6; cyclin-dependent kinase 6 isoform X1 [KO:K02091] [EC:2.7.11.22]
101004371  CCND2; G1/S-specific cyclin-D2 [KO:K10151]
100137215  CCND3; G1/S-specific cyclin-D3 [KO:K10152]
101004599  cyclin-dependent kinases regulatory subunit 1 [KO:K02219]
101004031  CKS1B; cyclin-dependent kinases regulatory subunit 1 [KO:K02219]
110740453  CKS2; cyclin-dependent kinases regulatory subunit 2 [KO:K02219]
101022453  SKP1; S-phase kinase-associated protein 1 [KO:K03094]
101000243  CUL1; cullin-1 [KO:K03347]
101025661  RBX1; E3 ubiquitin-protein ligase RBX1 isoform X1 [KO:K03868] [EC:2.3.2.32]
101000264  SKP2; S-phase kinase-associated protein 2 isoform X1 [KO:K03875]
101025892  CDK2; cyclin-dependent kinase 2 isoform X2 [KO:K02206] [EC:2.7.11.22]
101000606  CCNE1; G1/S-specific cyclin-E1 isoform X1 [KO:K06626]
101025307  CCNE2; G1/S-specific cyclin-E2 isoform X3 [KO:K06626]
101017005  RB1; retinoblastoma-associated protein [KO:K06618]
101014806  GADD45A; growth arrest and DNA damage-inducible protein GADD45 alpha [KO:K04402]
100997308  GADD45G; growth arrest and DNA damage-inducible protein GADD45 gamma [KO:K04402]
101012106  GADD45B; growth arrest and DNA damage-inducible protein GADD45 beta isoform X2 [KO:K04402]
101000115  BAK1; bcl-2 homologous antagonist/killer isoform X2 [KO:K14021]
100998564  DDB2; DNA damage-binding protein 2 isoform X1 [KO:K10140]
101006298  POLK; DNA polymerase kappa isoform X1 [KO:K03511] [EC:2.7.7.7]
101024790  TERT; telomerase reverse transcriptase [KO:K11126] [EC:2.7.7.49]
101010790  MITF; microphthalmia-associated transcription factor isoform X3 [KO:K09455]
101006627  TGFB1; transforming growth factor beta-1 proprotein isoform X1 [KO:K13375]
101009253  TGFB2; transforming growth factor beta-2 proprotein isoform X2 [KO:K13376]
100997116  TGFB3; transforming growth factor beta-3 proprotein [KO:K13377]
101016512  TGFBR1; TGF-beta receptor type-1 isoform X2 [KO:K04674] [EC:2.7.11.30]
101023107  TGFBR2; TGF-beta receptor type-2 isoform X2 [KO:K04388] [EC:2.7.11.30]
101004882  SMAD2; mothers against decapentaplegic homolog 2 isoform X2 [KO:K04500]
101013089  SMAD3; mothers against decapentaplegic homolog 3 isoform X1 [KO:K23605]
101019266  SMAD4; mothers against decapentaplegic homolog 4 [KO:K04501]
101001831  MECOM; histone-lysine N-methyltransferase MECOM isoform X7 [KO:K04462] [EC:2.1.1.367]
101016957  CTBP1; C-terminal-binding protein 1 isoform X2 [KO:K04496] [EC:1.1.1.428]
101023543  CTBP2; C-terminal-binding protein 2 isoform X4 [KO:K04496] [EC:1.1.1.428]
101024777  HDAC2; histone deacetylase 2 isoform X1 [KO:K06067] [EC:3.5.1.98]
101010160  HDAC1; histone deacetylase 1 isoform X1 [KO:K06067] [EC:3.5.1.98]
101013658  MLH1; DNA mismatch repair protein Mlh1 isoform X3 [KO:K08734]
101005434  MSH2; DNA mismatch repair protein Msh2 [KO:K08735]
101002001  MSH3; DNA mismatch repair protein Msh3 isoform X1 [KO:K08736]
101006470  MSH6; DNA mismatch repair protein Msh6 isoform X2 [KO:K08737]
101020669  BRCA2; breast cancer type 2 susceptibility protein isoform X1 [KO:K08775]
101017256  RAD51; DNA repair protein RAD51 homolog 1 [KO:K04482]
101000210  FASLG; tumor necrosis factor ligand superfamily member 6 [KO:K04389]
101017433  FADD; FAS-associated death domain protein [KO:K02373]
101009470  CASP8; caspase-8 isoform X1 [KO:K04398] [EC:3.4.22.61]
101008656  BID; BH3-interacting domain death agonist isoform X1 [KO:K04726]
101013691  PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1 isoform X2 [KO:K10131]
101021738  BBC3; bcl-2-binding component 3 isoform X1 [KO:K10132]
101010652  BCL2L11; bcl-2-like protein 11 isoform X1 [KO:K16341]
101025906  cytochrome c-like [KO:K08738]
101020480  cytochrome c-like [KO:K08738]
101021327  cytochrome c-like [KO:K08738]
101014039  cytochrome c-like [KO:K08738]
101008579  cytochrome c [KO:K08738]
100997529  cytochrome c [KO:K08738]
101021349  cytochrome c-like [KO:K08738]
100997503  cytochrome c-like [KO:K08738]
101019410  cytochrome c-like [KO:K08738]
103878393  cytochrome c-like [KO:K08738]
108582823  cytochrome c-like [KO:K08738]
101014473  cytochrome c-like [KO:K08738]
101023208  APAF1; apoptotic protease-activating factor 1 isoform X1 [KO:K02084]
100999117  CASP7; caspase-7 isoform X1 [KO:K04397] [EC:3.4.22.60]
101025614  KEAP1; kelch-like ECH-associated protein 1 [KO:K10456]
101023438  NFE2L2; nuclear factor erythroid 2-related factor 2 isoform X1 [KO:K05638]
100999853  HMOX1; heme oxygenase 1 [KO:K00510] [EC:1.14.14.18]
101010724  NQO1; NAD(P)H dehydrogenase [quinone] 1 [KO:K00355] [EC:1.6.5.2]
101022006  MGST1; microsomal glutathione S-transferase 1 [KO:K00799] [EC:2.5.1.18]
103883727  glutathione S-transferase alpha-4-like [KO:K00799] [EC:2.5.1.18]
101016734  MGST3; microsomal glutathione S-transferase 3 isoform X2 [KO:K00799] [EC:2.5.1.18]
101013512  glutathione S-transferase Mu 2 isoform X1 [KO:K00799] [EC:2.5.1.18]
101012891  GSTM4; glutathione S-transferase Mu 1 isoform X1 [KO:K00799] [EC:2.5.1.18]
101001730  glutathione S-transferase A3 isoform X1 [KO:K00799] [EC:2.5.1.18]
101003128  GSTA4; glutathione S-transferase A4 [KO:K00799] [EC:2.5.1.18]
101009553  GSTO2; glutathione S-transferase omega-2 isoform X1 [KO:K00799] [EC:2.5.1.18]
101001165  MGST2; microsomal glutathione S-transferase 2 isoform X2 [KO:K00799] [EC:2.5.1.18]
101014811  GSTM3; glutathione S-transferase Mu 3 isoform X2 [KO:K00799] [EC:2.5.1.18]
116273173  microsomal glutathione S-transferase 3-like [KO:K00799] [EC:2.5.1.18]
101005127  glutathione S-transferase A5 [KO:K00799] [EC:2.5.1.18]
101008775  GSTO1; glutathione S-transferase omega-1 [KO:K00799] [EC:2.5.1.18]
100997115  glutathione S-transferase Mu 5 isoform X2 [KO:K00799] [EC:2.5.1.18]
101015487  glutathione S-transferase theta-2B [KO:K00799] [EC:2.5.1.18]
101016081  glutathione S-transferase theta-1 isoform X1 [KO:K00799] [EC:2.5.1.18]
101015137  glutathione S-transferase theta-4 [KO:K00799] [EC:2.5.1.18]
101016449  glutathione S-transferase theta-4-like isoform X1 [KO:K00799] [EC:2.5.1.18]
101008213  GSTP1; glutathione S-transferase P [KO:K23790] [EC:2.5.1.18]
101018969  TXNRD1; thioredoxin reductase 1, cytoplasmic isoform X3 [KO:K22182] [EC:1.8.1.9]
101022248  TXNRD2; thioredoxin reductase 2, mitochondrial isoform X1 [KO:K22182] [EC:1.8.1.9]
101001486  TXNRD3; thioredoxin reductase 3 isoform X1 [KO:K22182] [EC:1.8.1.9]
101024033  VHL; von Hippel-Lindau disease tumor suppressor isoform X3 [KO:K03871]
101026337  ELOC; elongin-C isoform X1 [KO:K03872]
101008741  ELOB; elongin-B isoform X1 [KO:K03873]
101012633  CUL2; cullin-2 isoform X1 [KO:K03870]
101018094  EGLN3; egl nine homolog 3 [KO:K09592] [EC:1.14.11.29]
101006704  EGLN1; egl nine homolog 1 isoform X1 [KO:K09592] [EC:1.14.11.29]
100998148  EGLN2; egl nine homolog 2 isoform X1 [KO:K09592] [EC:1.14.11.29]
101002993  FH; fumarate hydratase, mitochondrial [KO:K01679] [EC:4.2.1.2]
100999094  HIF1A; hypoxia-inducible factor 1-alpha isoform X2 [KO:K08268]
103876915  EPAS1; endothelial PAS domain-containing protein 1 [KO:K09095]
101022512  ARNT; aryl hydrocarbon receptor nuclear translocator isoform X3 [KO:K09097]
101014765  ARNT2; aryl hydrocarbon receptor nuclear translocator 2 isoform X3 [KO:K15589]
101027061  EP300; histone acetyltransferase p300 isoform X1 [KO:K04498] [EC:2.3.1.48]
101002586  CREBBP; CREB-binding protein isoform X5 [KO:K04498] [EC:2.3.1.48]
100381181  SLC2A1; solute carrier family 2, facilitated glucose transporter member 1 [KO:K07299]
101005762  JAG1; protein jagged-1 [KO:K06052]
101006660  JAG2; protein jagged-2 isoform X1 [KO:K21635]
101006284  DLL1; delta-like protein 1 [KO:K06051]
101008609  DLL3; LOW QUALITY PROTEIN: delta-like protein 3 [KO:K06051]
101021496  DLL4; delta-like protein 4 [KO:K06051]
101007043  NOTCH1; neurogenic locus notch homolog protein 1 isoform X1 [KO:K02599]
101024262  NOTCH2; neurogenic locus notch homolog protein 2 isoform X1 [KO:K20994]
101007194  NOTCH3; LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 3 [KO:K20995]
101006374  HES1; transcription factor HES-1 [KO:K06054]
101024013  HES5; transcription factor HES-5 isoform X2 [KO:K06055]
100998649  HEYL; hairy/enhancer-of-split related with YRPW motif-like protein [KO:K09091]
101023494  HEY2; hairy/enhancer-of-split related with YRPW motif protein 2 isoform X1 [KO:K09091]
101005751  HEY1; hairy/enhancer-of-split related with YRPW motif protein 1 isoform X2 [KO:K09091]
101025494  FLT4; vascular endothelial growth factor receptor 3 isoform X1 [KO:K05097] [EC:2.7.10.1]
101020074  SHH; sonic hedgehog protein [KO:K11988]
101018770  PTCH1; protein patched homolog 1 isoform X1 [KO:K06225]
100999654  SMO; smoothened homolog isoform X1 [KO:K06226]
101025861  KIF7; kinesin-like protein KIF7 isoform X2 [KO:K18806]
101024354  SUFU; suppressor of fused homolog isoform X4 [KO:K06229]
101000297  GLI1; zinc finger protein GLI1 [KO:K16797]
101020631  GLI2; zinc finger protein GLI2 [KO:K16798]
101024392  GLI3; transcriptional activator GLI3 isoform X1 [KO:K06230]
101025190  BMP2; bone morphogenetic protein 2 [KO:K21283]
100137596  BMP4; bone morphogenetic protein 4 precursor [KO:K04662]
101012826  HHIP; hedgehog-interacting protein isoform X1 [KO:K06231]
101022723  PTCH2; protein patched homolog 2 isoform X3 [KO:K11101]
101020931  AR; androgen receptor isoform X1 [KO:K08557]
101000592  HSP90AB1; heat shock protein HSP 90-beta [KO:K04079]
101008161  HSP90AA1; heat shock protein HSP 90-alpha [KO:K04079]
101015403  HSP90B1; endoplasmin [KO:K09487]
100127349  KLK3; prostate-specific antigen precursor [KO:K01351] [EC:3.4.21.77]
Compound
C00027  Hydrogen peroxide
C00039  DNA
C00076  Calcium cation
C00122  Fumarate
C00149  (S)-Malate
C00165  Diacylglycerol
C00187  Cholesterol
C00280  Androstenedione
C00410  Progesterone
C00416  Phosphatidate
C00533  Nitric oxide
C00535  Testosterone
C00575  3',5'-Cyclic AMP
C00584  Prostaglandin E2
C00681  1-Acyl-sn-glycerol 3-phosphate
C00704  Superoxide
C00735  Cortisol
C00762  Cortisone
C00777  Retinoate
C00951  Estradiol-17beta
C01227  Dehydroepiandrosterone
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01471  Acrolein
C03917  Dihydrotestosterone
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C07653  Flutamide
C15493  9-cis-Retinoic acid
C16038  2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
C16844  Hydroxyl radical
C21641  Hydroperoxyl radical
C21642  4-Hydroxynonenal
Reference
  Authors
Weinberg RA.
  Title
The biology of cancer
  Journal
Garland Science, Taylor & Francis Group, LLC (2007)
Reference
PMID:10647931
  Authors
Hanahan D, Weinberg RA
  Title
The hallmarks of cancer.
  Journal
Cell 100:57-70 (2000)
DOI:10.1016/S0092-8674(00)81683-9
Reference
PMID:15000146
  Authors
Grady WM.
  Title
Genomic instability and colon cancer.
  Journal
Cancer Metastasis Rev 23:11-27 (2004)
DOI:10.1023/A:1025861527711
Reference
PMID:16555243
  Authors
Soreide K, Janssen EA, Soiland H, Korner H, Baak JP.
  Title
Microsatellite instability in colorectal cancer.
  Journal
Br J Surg 93:395-406 (2006)
DOI:10.1002/bjs.5328
Reference
PMID:11078609
  Authors
Anwar S, Hall C, White J, Deakin M, Farrell W, Elder JB.
  Title
Hereditary non-polyposis colorectal cancer: an updated review.
  Journal
Eur J Surg Oncol 26:635-45 (2000)
DOI:10.1053/ejso.2000.0974
Reference
PMID:16699851
  Authors
Takayama T, Miyanishi K, Hayashi T, Sato Y, Niitsu Y.
  Title
Colorectal cancer: genetics of development and metastasis.
  Journal
J Gastroenterol 41:185-92 (2006)
DOI:10.1007/s00535-006-1801-6
Reference
PMID:12621137
  Authors
Lynch HT, de la Chapelle A.
  Title
Hereditary colorectal cancer.
  Journal
N Engl J Med 348:919-32 (2003)
DOI:10.1056/NEJMra012242
Reference
PMID:12951588
  Authors
Rajagopalan H, Nowak MA, Vogelstein B, Lengauer C.
  Title
The significance of unstable chromosomes in colorectal cancer.
  Journal
Nat Rev Cancer 3:695-701 (2003)
DOI:10.1038/nrc1165
Reference
PMID:10505543
  Authors
Behrens J.
  Title
Cadherins and catenins: role in signal transduction and tumor progression.
  Journal
Cancer Metastasis Rev 18:15-30 (1999)
DOI:10.1023/A:1006200102166
Reference
PMID:16042571
  Authors
Behrens J.
  Title
The role of the Wnt signalling pathway in colorectal tumorigenesis.
  Journal
Biochem Soc Trans 33:672-5 (2005)
DOI:10.1042/BST0330672
Reference
PMID:15349822
  Authors
Behrens J, Lustig B.
  Title
The Wnt connection to tumorigenesis.
  Journal
Int J Dev Biol 48:477-87 (2004)
DOI:10.1387/ijdb.041815jb
Reference
PMID:9196022
  Authors
Polakis P.
  Title
The adenomatous polyposis coli (APC) tumor suppressor.
  Journal
Biochim Biophys Acta 1332:F127-47 (1997)
DOI:10.1016/S0304-419X(97)00008-5
Reference
PMID:12737309
  Authors
Janssen KP.
  Title
Murine models of colorectal cancer: studying the role of oncogenic K-ras.
  Journal
Cell Mol Life Sci 60:495-506 (2003)
DOI:10.1007/s000180300041
Reference
PMID:11459867
  Authors
Adjei AA.
  Title
Blocking oncogenic Ras signaling for cancer therapy.
  Journal
J Natl Cancer Inst 93:1062-74 (2001)
DOI:10.1093/jnci/93.14.1062
Reference
PMID:15573119
  Authors
Arakawa H.
  Title
Netrin-1 and its receptors in tumorigenesis.
  Journal
Nat Rev Cancer 4:978-87 (2004)
DOI:10.1038/nrc1504
Reference
PMID:15310786
  Authors
Mehlen P, Fearon ER.
  Title
Role of the dependence receptor DCC in colorectal cancer pathogenesis.
  Journal
J Clin Oncol 22:3420-8 (2004)
DOI:10.1200/JCO.2004.02.019
Reference
PMID:11223406
  Authors
Peltomaki P.
  Title
DNA mismatch repair and cancer.
  Journal
Mutat Res 488:77-85 (2001)
DOI:10.1016/S1383-5742(00)00058-2
Reference
PMID:15711891
  Authors
Li F, Cao Y, Townsend CM Jr, Ko TC.
  Title
TGF-beta signaling in colon cancer cells.
  Journal
World J Surg 29:306-11 (2005)
DOI:10.1007/s00268-004-7813-6
Reference
PMID:11170304
  Authors
Roman C, Saha D, Beauchamp R.
  Title
TGF-beta and colorectal carcinogenesis.
  Journal
Microsc Res Tech 52:450-7 (2001)
DOI:10.1002/1097-0029(20010215)52:4<450::AID-JEMT1030>3.0.CO;2-O
Reference
PMID:16326109
  Authors
Watson AJ.
  Title
An overview of apoptosis and the prevention of colorectal cancer.
  Journal
Crit Rev Oncol Hematol 57:107-21 (2006)
DOI:10.1016/j.critrevonc.2005.06.005
Reference
PMID:15479695
  Authors
Watson AJ.
  Title
Apoptosis and colorectal cancer.
  Journal
Gut 53:1701-9 (2004)
DOI:10.1136/gut.2004.052704
Reference
PMID:11477132
  Authors
Houlston RS.
  Title
What we could do now: molecular pathology of colorectal cancer.
  Journal
Mol Pathol 54:206-14 (2001)
DOI:10.1136/mp.54.4.206
Reference
  Authors
Von Hoff D, Evans D, Hruban R (ed).
  Title
Pancreatic cancer
  Journal
Jones and Bartlett publishers (2005)
Reference
  Authors
Niitsu Y, Yokota J (ed).
  Title
[Oncogenes and Tumor Suppressor Genes for Medical Oncologist] (In Japanese)
  Journal
Nankodo (1999)
Reference
PMID:12459728
  Authors
Bardeesy N, DePinho RA.
  Title
Pancreatic cancer biology and genetics.
  Journal
Nat Rev Cancer 2:897-909 (2002)
DOI:10.1038/nrc949
Reference
PMID:11407945
  Authors
Bardeesy N, Sharpless NE, DePinho RA, Merlino G.
  Title
The genetics of pancreatic adenocarcinoma: a roadmap for a mouse model.
  Journal
Semin Cancer Biol 11:201-18 (2001)
DOI:10.1006/scbi.2000.0371
Reference
PMID:12946833
  Authors
Cowgill SM, Muscarella P.
  Title
The genetics of pancreatic cancer.
  Journal
Am J Surg 186:279-86 (2003)
DOI:10.1016/S0002-9610(03)00226-5
Reference
PMID:16702400
  Authors
Hezel AF, Kimmelman AC, Stanger BZ, Bardeesy N, Depinho RA.
  Title
Genetics and biology of pancreatic ductal adenocarcinoma.
  Journal
Genes Dev 20:1218-49 (2006)
DOI:10.1101/gad.1415606
Reference
PMID:10740269
  Authors
Shields JM, Pruitt K, McFall A, Shaub A, Der CJ.
  Title
Understanding Ras: 'it ain't over 'til it's over'.
  Journal
Trends Cell Biol 10:147-54 (2000)
DOI:10.1016/S0962-8924(00)01740-2
Reference
PMID:12648469
  Authors
Holbro T, Civenni G, Hynes NE.
  Title
The ErbB receptors and their role in cancer progression.
  Journal
Exp Cell Res 284:99-110 (2003)
DOI:10.1016/S0014-4827(02)00099-X
Reference
PMID:14967450
  Authors
Marmor MD, Skaria KB, Yarden Y.
  Title
Signal transduction and oncogenesis by ErbB/HER receptors.
  Journal
Int J Radiat Oncol Biol Phys 58:903-13 (2004)
DOI:10.1016/j.ijrobp.2003.06.002
Reference
PMID:14586404
  Authors
DeArmond D, Brattain MG, Jessup JM, Kreisberg J, Malik S, Zhao S, Freeman JW.
  Title
Autocrine-mediated ErbB-2 kinase activation of STAT3 is required for growth factor independence of pancreatic cancer cell lines.
  Journal
Oncogene 22:7781-95 (2003)
DOI:10.1038/sj.onc.1206966
Reference
PMID:12545153
  Authors
Wei D, Le X, Zheng L, Wang L, Frey JA, Gao AC, Peng Z, Huang S, Xiong HQ, Abbruzzese JL, Xie K.
  Title
Stat3 activation regulates the expression of vascular endothelial growth factor and human pancreatic cancer angiogenesis and metastasis.
  Journal
Oncogene 22:319-29 (2003)
DOI:10.1038/sj.onc.1206122
Reference
PMID:14580692
  Authors
Toyonaga T, Nakano K, Nagano M, Zhao G, Yamaguchi K, Kuroki S, Eguchi T, Chijiiwa K, Tsuneyoshi M, Tanaka M.
  Title
Blockade of constitutively activated Janus kinase/signal transducer and activator of transcription-3 pathway inhibits growth of human pancreatic cancer.
  Journal
Cancer Lett 201:107-16 (2003)
DOI:10.1016/S0304-3835(03)00482-8
Reference
PMID:12079267
  Authors
Schmid RM.
  Title
Genetic basis of pancreatic cancer.
  Journal
Best Pract Res Clin Gastroenterol 16:421-33 (2002)
DOI:10.1053/bega.2002.0316
Reference
PMID:15774796
  Authors
Elliott RL, Blobe GC.
  Title
Role of transforming growth factor Beta in human cancer.
  Journal
J Clin Oncol 23:2078-93 (2005)
DOI:10.1200/JCO.2005.02.047
Reference
PMID:15823750
  Authors
Rudkin TM, Foulkes WD.
  Title
BRCA2: breaks, mistakes and failed separations.
  Journal
Trends Mol Med 11:145-8 (2005)
DOI:10.1016/j.molmed.2005.02.003
Reference
PMID:11707511
  Authors
Venkitaraman AR.
  Title
Functions of BRCA1 and BRCA2 in the biological response to DNA damage.
  Journal
J Cell Sci 114:3591-8 (2001)
Reference
PMID:15639402
  Authors
Soni D, King JA, Kaye AH, Hovens CM.
  Title
Genetics of glioblastoma multiforme: mitogenic signaling and cell cycle pathways converge.
  Journal
J Clin Neurosci 12:1-5 (2005)
DOI:10.1016/j.jocn.2004.04.001
Reference
PMID:12154354
  Authors
Zhu Y, Parada LF.
  Title
The molecular and genetic basis of neurological tumours.
  Journal
Nat Rev Cancer 2:616-26 (2002)
DOI:10.1038/nrc866
Reference
PMID:11253051
  Authors
Holland EC.
  Title
Gliomagenesis: genetic alterations and mouse models.
  Journal
Nat Rev Genet 2:120-9 (2001)
DOI:10.1038/35052535
Reference
PMID:16700615
  Authors
Bansal K, Liang ML, Rutka JT.
  Title
Molecular biology of human gliomas.
  Journal
Technol Cancer Res Treat 5:185-94 (2006)
DOI:10.1177/153303460600500302
Reference
  Authors
Tabuchi K (ed).
  Title
[Gliomas: Research and therapy] (In Japanese)
  Journal
Springer-Verlag Tokyo (2006)
Reference
PMID:12762887
  Authors
Kapoor GS, O'Rourke DM.
  Title
Mitogenic signaling cascades in glial tumors.
  Journal
Neurosurgery 52:1425-34; discussion 1434-5 (2003)
DOI:10.1227/01.NEU.0000065135.28143.39
Reference
PMID:16095998
  Authors
Hulleman E, Helin K.
  Title
Molecular mechanisms in gliomagenesis.
  Journal
Adv Cancer Res 94:1-27 (2005)
DOI:10.1016/S0065-230X(05)94001-3
Reference
PMID:11057895
  Authors
Schlessinger J.
  Title
Cell signaling by receptor tyrosine kinases.
  Journal
Cell 103:211-25 (2000)
DOI:10.1016/S0092-8674(00)00114-8
Reference
PMID:9643506
  Authors
Ng HK, Lam PY.
  Title
The molecular genetics of central nervous system tumors.
  Journal
Pathology 30:196-202 (1998)
DOI:10.1080/00313029800169236
Reference
PMID:12084351
  Authors
Knobbe CB, Merlo A, Reifenberger G.
  Title
Pten signaling in gliomas.
  Journal
Neuro-oncol 4:196-211 (2002)
DOI:10.1093/neuonc/4.3.196
Reference
PMID:16557281
  Authors
Kondo T, Ezzat S, Asa SL.
  Title
Pathogenetic mechanisms in thyroid follicular-cell neoplasia.
  Journal
Nat Rev Cancer 6:292-306 (2006)
DOI:10.1038/nrc1836
Reference
PMID:16551846
  Authors
Chiloeches A, Marais R.
  Title
Is BRAF the Achilles' Heel of thyroid cancer?
  Journal
Clin Cancer Res 12:1661-4 (2006)
DOI:10.1158/1078-0432.CCR-06-0051
Reference
PMID:16946003
  Authors
Reddi HV, McIver B, Grebe SK, Eberhardt NL
  Title
The paired box-8/peroxisome proliferator-activated receptor-gamma oncogene in thyroid tumorigenesis.
  Journal
Endocrinology 148:932-5 (2007)
DOI:10.1210/en.2006-0926
Reference
PMID:17062879
  Authors
Santoro M, Melillo RM, Fusco A.
  Title
RET/PTC activation in papillary thyroid carcinoma: European Journal of Endocrinology Prize Lecture.
  Journal
Eur J Endocrinol 155:645-653 (2006)
DOI:10.1530/eje.1.02289
Reference
PMID:16242838
  Authors
Pierotti MA, Greco A.
  Title
Oncogenic rearrangements of the NTRK1/NGF receptor.
  Journal
Cancer Lett 232:90-8 (2006)
DOI:10.1016/j.canlet.2005.07.043
Reference
PMID:16189702
  Authors
Sobrinho-Simoes M, Preto A, Rocha AS, Castro P, Maximo V, Fonseca E, Soares P.
  Title
Molecular pathology of well-differentiated thyroid carcinomas.
  Journal
Virchows Arch 447:787-93 (2005)
DOI:10.1007/s00428-005-0065-5
Reference
PMID:11165748
  Authors
Gimm O.
  Title
Thyroid cancer.
  Journal
Cancer Lett 163:143-56 (2001)
DOI:10.1016/S0304-3835(00)00697-2
Reference
PMID:12094241
  Authors
Williams D.
  Title
Cancer after nuclear fallout: lessons from the Chernobyl accident.
  Journal
Nat Rev Cancer 2:543-9 (2002)
DOI:10.1038/nrc845
Reference
PMID:16236521
  Authors
Steffen B, Muller-Tidow C, Schwable J, Berdel WE, Serve H.
  Title
The molecular pathogenesis of acute myeloid leukemia.
  Journal
Crit Rev Oncol Hematol 56:195-221 (2005)
DOI:10.1016/j.critrevonc.2004.10.012
Reference
PMID:12563308
  Authors
Tenen DG.
  Title
Disruption of differentiation in human cancer: AML shows the way.
  Journal
Nat Rev Cancer 3:89-101 (2003)
DOI:10.1038/nrc989
Reference
PMID:16146838
  Authors
Choudhary C, Muller-Tidow C, Berdel WE, Serve H.
  Title
Signal transduction of oncogenic Flt3.
  Journal
Int J Hematol 82:93-9 (2005)
DOI:10.1532/IJH97.05090
Reference
PMID:12951584
  Authors
Stirewalt DL, Radich JP.
  Title
The role of FLT3 in haematopoietic malignancies.
  Journal
Nat Rev Cancer 3:650-65 (2003)
DOI:10.1038/nrc1169
Reference
PMID:16642045
  Authors
Martelli AM, Nyakern M, Tabellini G, Bortul R, Tazzari PL, Evangelisti C, Cocco L.
  Title
Phosphoinositide 3-kinase/Akt signaling pathway and its therapeutical implications for human acute myeloid leukemia.
  Journal
Leukemia 20:911-28 (2006)
DOI:10.1038/sj.leu.2404245
Reference
PMID:15625120
  Authors
Lennartsson J, Jelacic T, Linnekin D, Shivakrupa R.
  Title
Normal and oncogenic forms of the receptor tyrosine kinase kit.
  Journal
Stem Cells 23:16-43 (2005)
DOI:10.1634/stemcells.2004-0117
Reference
PMID:11721960
  Authors
Lorsbach RB, Downing JR.
  Title
The role of the AML1 transcription factor in leukemogenesis.
  Journal
Int J Hematol 74:258-65 (2001)
DOI:10.1007/BF02982058
Reference
PMID:12468433
  Authors
Mizuki M, Schwable J, Steur C, Choudhary C, Agrawal S, Sargin B, Steffen B, Matsumura I, Kanakura Y, Bohmer FD, Muller-Tidow C, Berdel WE, Serve H.
  Title
Suppression of myeloid transcription factors and induction of STAT response genes by AML-specific Flt3 mutations.
  Journal
Blood 101:3164-73 (2003)
DOI:10.1182/blood-2002-06-1677
Reference
PMID:17554387
  Authors
Mikesch JH, Steffen B, Berdel WE, Serve H, Muller-Tidow C.
  Title
The emerging role of Wnt signaling in the pathogenesis of acute myeloid leukemia.
  Journal
Leukemia 21:1638-47 (2007)
DOI:10.1038/sj.leu.2404732
Reference
PMID:16352814
  Authors
Mueller BU, Pabst T, Fos J, Petkovic V, Fey MF, Asou N, Buergi U, Tenen DG.
  Title
ATRA resolves the differentiation block in t(15;17) acute myeloid leukemia by restoring PU.1 expression.
  Journal
Blood 107:3330-8 (2006)
DOI:10.1182/blood-2005-07-3068
Reference
PMID:15719031
  Authors
Ren R.
  Title
Mechanisms of BCR-ABL in the pathogenesis of chronic myelogenous leukaemia.
  Journal
Nat Rev Cancer 5:172-83 (2005)
DOI:10.1038/nrc1567
Reference
PMID:11071626
  Authors
Deininger MW, Goldman JM, Melo JV.
  Title
The molecular biology of chronic myeloid leukemia.
  Journal
Blood 96:3343-56 (2000)
Reference
PMID:14982876
  Authors
Calabretta B, Perrotti D.
  Title
The biology of CML blast crisis.
  Journal
Blood 103:4010-22 (2004)
DOI:10.1182/blood-2003-12-4111
Reference
PMID:10403855
  Authors
Faderl S, Talpaz M, Estrov Z, O'Brien S, Kurzrock R, Kantarjian HM.
  Title
The biology of chronic myeloid leukemia.
  Journal
N Engl J Med 341:164-72 (1999)
DOI:10.1056/NEJM199907153410306
Reference
PMID:15156182
  Authors
Mitani K.
  Title
Molecular mechanisms of leukemogenesis by AML1/EVI-1.
  Journal
Oncogene 23:4263-9 (2004)
DOI:10.1038/sj.onc.1207777
Reference
PMID:16484590
  Authors
Dong M, Blobe GC.
  Title
Role of transforming growth factor-beta in hematologic malignancies.
  Journal
Blood 107:4589-96 (2006)
DOI:10.1182/blood-2005-10-4169
Reference
PMID:9834202
  Authors
Kurokawa M, Mitani K, Imai Y, Ogawa S, Yazaki Y, Hirai H.
  Title
The t(3;21) fusion product, AML1/Evi-1, interacts with Smad3 and blocks transforming growth factor-beta-mediated growth inhibition of myeloid cells.
  Journal
Blood 92:4003-12 (1998)
Reference
PMID:12801837
  Authors
Brusa G, Benvenuti M, Mazzacurati L, Mancini M, Pattacini L, Martinelli G, Barbieri E, Greenberger JS, Baccarani M, Santucci MA.
  Title
p53 loss of function enhances genomic instability and accelerates clonal evolution of murine myeloid progenitors expressing the p(210)BCR-ABL tyrosine kinase.
  Journal
Haematologica 88:622-30 (2003)
Reference
PMID:11160144
  Authors
Baldwin AS.
  Title
Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kappaB.
  Journal
J Clin Invest 107:241-6 (2001)
DOI:10.1172/JCI11991
Reference
PMID:12244301
  Authors
Shin I, Yakes FM, Rojo F, Shin NY, Bakin AV, Baselga J, Arteaga CL.
  Title
PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localization.
  Journal
Nat Med 8:1145-52 (2002)
DOI:10.1038/nm759
Reference
PMID:15948971
  Authors
Tilli CM, Van Steensel MA, Krekels GA, Neumann HA, Ramaekers FC.
  Title
Molecular aetiology and pathogenesis of basal cell carcinoma.
  Journal
Br J Dermatol 152:1108-24 (2005)
DOI:10.1111/j.1365-2133.2005.06587.x
Reference
PMID:12588368
  Authors
Saldanha G, Fletcher A, Slater DN.
  Title
Basal cell carcinoma: a dermatopathological and molecular biological update.
  Journal
Br J Dermatol 148:195-202 (2003)
DOI:10.1046/j.1365-2133.2003.05151.x
Reference
PMID:15978322
  Authors
Daya-Grosjean L, Couve-Privat S.
  Title
Sonic hedgehog signaling in basal cell carcinomas.
  Journal
Cancer Lett 225:181-92 (2005)
DOI:10.1016/j.canlet.2004.10.003
Reference
PMID:15468170
  Authors
Tsai KY, Tsao H.
  Title
The genetics of skin cancer.
  Journal
Am J Med Genet C Semin Med Genet 131C:82-92 (2004)
DOI:10.1002/ajmg.c.30037
Reference
PMID:16881963
  Authors
Athar M, Tang X, Lee JL, Kopelovich L, Kim AL.
  Title
Hedgehog signalling in skin development and cancer.
  Journal
Exp Dermatol 15:667-77 (2006)
DOI:10.1111/j.1600-0625.2006.00473.x
Reference
PMID:16306523
  Authors
Rubin AI, Chen EH, Ratner D.
  Title
Basal-cell carcinoma.
  Journal
N Engl J Med 353:2262-9 (2005)
DOI:10.1056/NEJMra044151
Reference
PMID:11276000
  Authors
Saldanha G.
  Title
The Hedgehog signalling pathway and cancer.
  Journal
J Pathol 193:427-32 (2001)
DOI:10.1002/1096-9896(2000)9999:9999<::AID-PATH815>3.0.CO;2-N
Reference
PMID:15270885
  Authors
Saldanha G, Ghura V, Potter L, Fletcher A.
  Title
Nuclear beta-catenin in basal cell carcinoma correlates with increased proliferation.
  Journal
Br J Dermatol 151:157-64 (2004)
DOI:10.1111/j.1365-2133.2004.06048.x
Reference
PMID:14737121
  Authors
Pasca di Magliano M, Hebrok M.
  Title
Hedgehog signalling in cancer formation and maintenance.
  Journal
Nat Rev Cancer 3:903-11 (2003)
DOI:10.1038/nrc1229
Reference
PMID:15656799
  Authors
Reifenberger J, Wolter M, Knobbe CB, Kohler B, Schonicke A, Scharwachter C, Kumar K, Blaschke B, Ruzicka T, Reifenberger G.
  Title
Somatic mutations in the PTCH, SMOH, SUFUH and TP53 genes in sporadic basal cell carcinomas.
  Journal
Br J Dermatol 152:43-51 (2005)
DOI:10.1111/j.1365-2133.2005.06353.x
Reference
PMID:14556242
  Authors
Cohen MM Jr.
  Title
The hedgehog signaling network.
  Journal
Am J Med Genet A 123:5-28 (2003)
DOI:10.1002/ajmg.a.20495
Reference
PMID:11736900
  Authors
Yamazaki F, Aragane Y, Kawada A, Tezuka T.
  Title
Immunohistochemical detection for nuclear beta-catenin in sporadic basal cell carcinoma.
  Journal
Br J Dermatol 145:771-7 (2001)
DOI:10.1046/j.1365-2133.2001.04468.x
Reference
PMID:16054233
  Authors
Erb P, Ji J, Wernli M, Kump E, Glaser A, Buchner SA.
  Title
Role of apoptosis in basal cell and squamous cell carcinoma formation.
  Journal
Immunol Lett 100:68-72 (2005)
DOI:10.1016/j.imlet.2005.06.008
Reference
PMID:11130178
  Authors
Toftgard R.
  Title
Hedgehog signalling in cancer.
  Journal
Cell Mol Life Sci 57:1720-31 (2000)
DOI:10.1007/PL00000654
Reference
PMID:16822996
  Authors
Miller AJ, Mihm MC Jr.
  Title
Melanoma.
  Journal
N Engl J Med 355:51-65 (2006)
DOI:10.1056/NEJMra052166
Reference
PMID:12894244
  Authors
Chin L.
  Title
The genetics of malignant melanoma: lessons from mouse and man.
  Journal
Nat Rev Cancer 3:559-70 (2003)
DOI:10.1038/nrc1145
Reference
PMID:16750612
  Authors
Takata M, Saida T.
  Title
Genetic alterations in melanocytic tumors.
  Journal
J Dermatol Sci 43:1-10 (2006)
DOI:10.1016/j.jdermsci.2006.05.002
Reference
PMID:15841168
  Authors
Chudnovsky Y, Khavari PA, Adams AE.
  Title
Melanoma genetics and the development of rational therapeutics.
  Journal
J Clin Invest 115:813-24 (2005)
DOI:10.1172/JCI24808
Reference
PMID:16001050
  Authors
Merlino G.
  Title
Cancer biology: the weakest link?
  Journal
Nature 436:33-5 (2005)
DOI:10.1038/436033a
Reference
PMID:16001072
  Authors
Garraway LA, Widlund HR, Rubin MA, Getz G, Berger AJ, Ramaswamy S, Beroukhim R, Milner DA, Granter SR, Du J, Lee C, Wagner SN, Li C, Golub TR, Rimm DL, Meyerson ML, Fisher DE, Sellers WR.
  Title
Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma.
  Journal
Nature 436:117-22 (2005)
DOI:10.1038/nature03664
Reference
PMID:16899407
  Authors
Levy C, Khaled M, Fisher DE.
  Title
MITF: master regulator of melanocyte development and melanoma oncogene.
  Journal
Trends Mol Med 12:406-14 (2006)
DOI:10.1016/j.molmed.2006.07.008
Reference
PMID:15009714
  Authors
Tsao H, Goel V, Wu H, Yang G, Haluska FG.
  Title
Genetic interaction between NRAS and BRAF mutations and PTEN/MMAC1 inactivation in melanoma.
  Journal
J Invest Dermatol 122:337-41 (2004)
DOI:10.1046/j.0022-202X.2004.22243.x
Reference
PMID:11224709
  Authors
Gruss C, Herlyn M.
  Title
Role of cadherins and matrixins in melanoma.
  Journal
Curr Opin Oncol 13:117-23 (2001)
DOI:10.1097/00001622-200103000-00006
Reference
PMID:15721476
  Authors
Thompson JF, Scolyer RA, Kefford RF.
  Title
Cutaneous melanoma.
  Journal
Lancet 365:687-701 (2005)
DOI:10.1016/S0140-6736(05)17951-3
Reference
PMID:14695152
  Authors
Omholt K, Platz A, Kanter L, Ringborg U, Hansson J.
  Title
NRAS and BRAF mutations arise early during melanoma pathogenesis and are preserved throughout tumor progression.
  Journal
Clin Cancer Res 9:6483-8 (2003)
Reference
PMID:15557758
  Authors
Hussein MR.
  Title
The TP53 tumor suppressor gene and melanoma tumorigenesis: is there a relationship?
  Journal
Tumour Biol 25:200-7 (2004)
DOI:10.1159/000081103
Reference
PMID:10843728
  Authors
Lazar-Molnar E, Hegyesi H, Toth S, Falus A.
  Title
Autocrine and paracrine regulation by cytokines and growth factors in melanoma.
  Journal
Cytokine 12:547-54 (2000)
DOI:10.1006/cyto.1999.0614
Reference
PMID:16339096
  Authors
Cohen HT, McGovern FJ.
  Title
Renal-cell carcinoma.
  Journal
N Engl J Med 353:2477-90 (2005)
DOI:10.1056/NEJMra043172
Reference
PMID:15122209
  Authors
Pavlovich CP, Schmidt LS.
  Title
Searching for the hereditary causes of renal-cell carcinoma.
  Journal
Nat Rev Cancer 4:381-93 (2004)
DOI:10.1038/nrc1364
Reference
PMID:14634372
  Authors
Linehan WM, Walther MM, Zbar B.
  Title
The genetic basis of cancer of the kidney.
  Journal
J Urol 170:2163-72 (2003)
DOI:10.1097/01.ju.0000096060.92397.ed
Reference
PMID:14685170
  Authors
Birchmeier C, Birchmeier W, Gherardi E, Vande Woude GF.
  Title
Met, metastasis, motility and more.
  Journal
Nat Rev Mol Cell Biol 4:915-25 (2003)
DOI:10.1038/nrm1261
Reference
PMID:15611513
  Authors
Kim WY, Kaelin WG.
  Title
Role of VHL gene mutation in human cancer.
  Journal
J Clin Oncol 22:4991-5004 (2004)
DOI:10.1200/JCO.2004.05.061
Reference
PMID:17211469
  Authors
Sudarshan S, Linehan WM, Neckers L.
  Title
HIF and fumarate hydratase in renal cancer.
  Journal
Br J Cancer 96:403-7 (2007)
DOI:10.1038/sj.bjc.6603547
Reference
PMID:17287871
  Authors
Sudarshan S, Pinto PA, Neckers L, Linehan WM.
  Title
Mechanisms of disease: hereditary leiomyomatosis and renal cell cancer--a distinct form of hereditary kidney cancer.
  Journal
Nat Clin Pract Urol 4:104-10 (2007)
DOI:10.1038/ncpuro0711
Reference
PMID:12351585
  Authors
Bodmer D, van den Hurk W, van Groningen JJ, Eleveld MJ, Martens GJ, Weterman MA, van Kessel AG.
  Title
Understanding familial and non-familial renal cell cancer.
  Journal
Hum Mol Genet 11:2489-98 (2002)
DOI:10.1093/hmg/11.20.2489
Reference
PMID:17158541
  Authors
Mitra AP, Datar RH, Cote RJ.
  Title
Molecular pathways in invasive bladder cancer: new insights into mechanisms, progression, and target identification.
  Journal
J Clin Oncol 24:5552-64 (2006)
DOI:10.1200/JCO.2006.08.2073
Reference
PMID:16474624
  Authors
Wolff EM, Liang G, Jones PA.
  Title
Mechanisms of Disease: genetic and epigenetic alterations that drive bladder cancer.
  Journal
Nat Clin Pract Urol 2:502-10 (2005)
DOI:10.1038/ncpuro0318
Reference
PMID:16110317
  Authors
Wu XR.
  Title
Urothelial tumorigenesis: a tale of divergent pathways.
  Journal
Nat Rev Cancer 5:713-25 (2005)
DOI:10.1038/nrc1697
Reference
PMID:11103787
  Authors
Brown NS, Jones A, Fujiyama C, Harris AL, Bicknell R.
  Title
Thymidine phosphorylase induces carcinoma cell oxidative stress and promotes secretion of angiogenic factors.
  Journal
Cancer Res 60:6298-302 (2000)
Reference
PMID:12850530
  Authors
Bellmunt J, Hussain M, Dinney CP.
  Title
Novel approaches with targeted therapies in bladder cancer. Therapy of bladder cancer by blockade of the epidermal growth factor receptor family.
  Journal
Crit Rev Oncol Hematol 46 Suppl:S85-104 (2003)
DOI:10.1016/S1040-8428(03)00067-2
Reference
PMID:17149381
  Authors
Sugano K, Kakizoe T.
  Title
Genetic alterations in bladder cancer and their clinical applications in molecular tumor staging.
  Journal
Nat Clin Pract Urol 3:642-52 (2006)
DOI:10.1038/ncpuro0649
Reference
PMID:15746962
  Authors
Dunn KL, Espino PS, Drobic B, He S, Davie JR.
  Title
The Ras-MAPK signal transduction pathway, cancer and chromatin remodeling.
  Journal
Biochem Cell Biol 83:1-14 (2005)
DOI:10.1139/o04-121
Reference
PMID:15551095
  Authors
Williams SG, Stein JP.
  Title
Molecular pathways in bladder cancer.
  Journal
Urol Res 32:373-85 (2004)
DOI:10.1007/s00240-003-0345-y
Reference
PMID:12878745
  Authors
Nelson WG, De Marzo AM, Isaacs WB.
  Title
Prostate cancer.
  Journal
N Engl J Med 349:366-81 (2003)
DOI:10.1056/NEJMra021562
Reference
PMID:15724144
  Authors
Li L, Ittmann MM, Ayala G, Tsai MJ, Amato RJ, Wheeler TM, Miles BJ, Kadmon D, Thompson TC.
  Title
The emerging role of the PI3-K-Akt pathway in prostate cancer progression.
  Journal
Prostate Cancer Prostatic Dis 8:108-18 (2005)
DOI:10.1038/sj.pcan.4500776
Reference
PMID:16551847
  Authors
Pienta KJ, Bradley D.
  Title
Mechanisms underlying the development of androgen-independent prostate cancer.
  Journal
Clin Cancer Res 12:1665-71 (2006)
DOI:10.1158/1078-0432.CCR-06-0067
Reference
PMID:11900250
  Authors
Feldman BJ, Feldman D.
  Title
The development of androgen-independent prostate cancer.
  Journal
Nat Rev Cancer 1:34-45 (2001)
DOI:10.1038/35094009
Reference
PMID:15082523
  Authors
Heinlein CA, Chang C.
  Title
Androgen receptor in prostate cancer.
  Journal
Endocr Rev 25:276-308 (2004)
DOI:10.1210/er.2002-0032
Reference
PMID:9422516
  Authors
Koivisto P, Kolmer M, Visakorpi T, Kallioniemi OP.
  Title
Androgen receptor gene and hormonal therapy failure of prostate cancer.
  Journal
Am J Pathol 152:1-9 (1998)
Reference
PMID:10835690
  Authors
Zhao XY, Malloy PJ, Krishnan AV, Swami S, Navone NM, Peehl DM, Feldman D.
  Title
Glucocorticoids can promote androgen-independent growth of prostate cancer cells through a mutated androgen receptor.
  Journal
Nat Med 6:703-6 (2000)
DOI:10.1038/76287
Reference
PMID:10453277
  Authors
Macri E, Loda M.
  Title
Role of p27 in prostate carcinogenesis.
  Journal
Cancer Metastasis Rev 17:337-44 (1998)
DOI:10.1023/A:1006133620914
Reference
PMID:11750244
  Authors
Steers WD.
  Title
5alpha-reductase activity in the prostate.
  Journal
Urology 58:17-24; discussion 24 (2001)
DOI:10.1016/S0090-4295(01)01299-7
Reference
PMID:8069858
  Authors
Lin D, Meyer DJ, Ketterer B, Lang NP, Kadlubar FF.
  Title
Effects of human and rat glutathione S-transferases on the covalent DNA binding of the N-acetoxy derivatives of heterocyclic amine carcinogens in vitro: a possible mechanism of organ specificity in their carcinogenesis.
  Journal
Cancer Res 54:4920-6 (1994)
Reference
PMID:11527574
  Authors
Grimes CA, Jope RS.
  Title
The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling.
  Journal
Prog Neurobiol 65:391-426 (2001)
DOI:10.1016/S0301-0082(01)00011-9
Reference
PMID:15947972
  Authors
Ryan AJ, Susil B, Jobling TW, Oehler MK.
  Title
Endometrial cancer.
  Journal
Cell Tissue Res 322:53-61 (2005)
DOI:10.1007/s00441-005-1109-5
Reference
PMID:14747944
  Authors
Lax SF.
  Title
Molecular genetic pathways in various types of endometrial carcinoma: from a phenotypical to a molecular-based classification.
  Journal
Virchows Arch 444:213-23 (2004)
DOI:10.1007/s00428-003-0947-3
Reference
PMID:16508724
  Authors
Shiozawa T, Konishi I.
  Title
Early endometrial carcinoma: clinicopathology, hormonal aspects, molecular genetics, diagnosis, and treatment.
  Journal
Int J Clin Oncol 11:13-21 (2006)
DOI:10.1007/s10147-005-0546-1
Reference
PMID:17028294
  Authors
Hecht JL, Mutter GL.
  Title
Molecular and pathologic aspects of endometrial carcinogenesis.
  Journal
J Clin Oncol 24:4783-91 (2006)
DOI:10.1200/JCO.2006.06.7173
Reference
PMID:11431710
  Authors
Matias-Guiu X, Catasus L, Bussaglia E, Lagarda H, Garcia A, Pons C, Munoz J, Arguelles R, Machin P, Prat J.
  Title
Molecular pathology of endometrial hyperplasia and carcinoma.
  Journal
Hum Pathol 32:569-77 (2001)
DOI:10.1053/hupa.2001.25929
Reference
PMID:15284264
  Authors
Slomovitz BM, Broaddus RR, Burke TW, Sneige N, Soliman PT, Wu W, Sun CC, Munsell MF, Gershenson DM, Lu KH.
  Title
Her-2/neu overexpression and amplification in uterine papillary serous carcinoma.
  Journal
J Clin Oncol 22:3126-32 (2004)
DOI:10.1200/JCO.2004.11.154
Reference
PMID:7585656
  Authors
Saffari B, Jones LA, el-Naggar A, Felix JC, George J, Press MF.
  Title
Amplification and overexpression of HER-2/neu (c-erbB2) in endometrial cancers: correlation with overall survival.
  Journal
Cancer Res 55:5693-8 (1995)
Reference
PMID:16248975
  Authors
Kim D, Chung J.
  Title
Akt: versatile mediator of cell survival and beyond.
  Journal
J Biochem Mol Biol 35:106-15 (2002)
DOI:10.5483/bmbrep.2002.35.1.106
Reference
PMID:12711111
  Authors
Sanchez-Cespedes M.
  Title
Dissecting the genetic alterations involved in lung carcinogenesis.
  Journal
Lung Cancer 40:111-21 (2003)
DOI:10.1016/S0169-5002(03)00033-3
Reference
PMID:11720739
  Authors
Kaye FJ.
  Title
Molecular biology of lung cancer.
  Journal
Lung Cancer 34 Suppl 2:S35-41 (2001)
DOI:10.1016/S0169-5002(01)00342-7
Reference
PMID:12616528
  Authors
Shivapurkar N, Reddy J, Chaudhary PM, Gazdar AF.
  Title
Apoptosis and lung cancer: a review.
  Journal
J Cell Biochem 88:885-98 (2003)
DOI:10.1002/jcb.10440
Reference
PMID:11807782
  Authors
Sartorius UA, Krammer PH.
  Title
Upregulation of Bcl-2 is involved in the mediation of chemotherapy resistance in human small cell lung cancer cell lines.
  Journal
Int J Cancer 97:584-92 (2002)
DOI:10.1002/ijc.10096
Reference
PMID:16064138
  Authors
Adhikary S, Eilers M.
  Title
Transcriptional regulation and transformation by Myc proteins.
  Journal
Nat Rev Mol Cell Biol 6:635-45 (2005)
DOI:10.1038/nrm1703
Reference
PMID:11463388
  Authors
Spruck C, Strohmaier H, Watson M, Smith AP, Ryan A, Krek TW, Reed SI.
  Title
A CDK-independent function of mammalian Cks1: targeting of SCF(Skp2) to the CDK inhibitor p27Kip1.
  Journal
Mol Cell 7:639-50 (2001)
DOI:10.1016/S1097-2765(01)00210-6
Reference
PMID:15109562
  Authors
Buttery RC, Rintoul RC, Sethi T.
  Title
Small cell lung cancer: the importance of the extracellular matrix.
  Journal
Int J Biochem Cell Biol 36:1154-60 (2004)
DOI:10.1016/S1357-2725(03)00261-9
Reference
PMID:11559746
  Authors
Yamada KM, Araki M.
  Title
Tumor suppressor PTEN: modulator of cell signaling, growth, migration and apoptosis.
  Journal
J Cell Sci 114:2375-82 (2001)
Reference
PMID:11905738
  Authors
Rintoul RC, Sethi T.
  Title
The role of extracellular matrix in small-cell lung cancer.
  Journal
Lancet Oncol 2:437-42 (2001)
DOI:10.1016/S1470-2045(00)00421-6
Reference
PMID:12243753
  Authors
Ekedahl J, Joseph B, Grigoriev MY, Muller M, Magnusson C, Lewensohn R, Zhivotovsky B.
  Title
Expression of inhibitor of apoptosis proteins in small- and non-small-cell lung carcinoma cells.
  Journal
Exp Cell Res 279:277-90 (2002)
DOI:10.1006/excr.2002.5608
Reference
PMID:12379883
  Authors
Osada H, Takahashi T.
  Title
Genetic alterations of multiple tumor suppressors and oncogenes in the carcinogenesis and progression of lung cancer.
  Journal
Oncogene 21:7421-34 (2002)
DOI:10.1038/sj.onc.1205802
Reference
PMID:12741677
  Authors
Yokota J, Nishioka M, Tani M, Kohno T.
  Title
Genetic alterations responsible for metastatic phenotypes of lung cancer cells.
  Journal
Clin Exp Metastasis 20:189-93 (2003)
DOI:10.1023/a:1022978932215
Reference
PMID:16870043
  Authors
Aviel-Ronen S, Blackhall FH, Shepherd FA, Tsao MS.
  Title
K-ras mutations in non-small-cell lung carcinoma: a review.
  Journal
Clin Lung Cancer 8:30-8 (2006)
DOI:10.3816/CLC.2006.n.030
Reference
PMID:15948711
  Authors
Pfeifer GP, Dammann R.
  Title
Methylation of the tumor suppressor gene RASSF1A in human tumors.
  Journal
Biochemistry (Mosc) 70:576-83 (2005)
DOI:10.1007/s10541-005-0151-y
Reference
PMID:11902573
  Authors
Altucci L, Gronemeyer H.
  Title
The promise of retinoids to fight against cancer.
  Journal
Nat Rev Cancer 1:181-93 (2001)
DOI:10.1038/35106036
Reference
PMID:10944551
  Authors
Virmani AK, Rathi A, Zochbauer-Muller S, Sacchi N, Fukuyama Y, Bryant D, Maitra A, Heda S, Fong KM, Thunnissen F, Minna JD, Gazdar AF.
  Title
Promoter methylation and silencing of the retinoic acid receptor-beta gene in lung carcinomas.
  Journal
J Natl Cancer Inst 92:1303-7 (2000)
DOI:10.1093/jnci/92.16.1303
Reference
PMID:12867060
  Authors
Hirsch FR, Scagliotti GV, Langer CJ, Varella-Garcia M, Franklin WA.
  Title
Epidermal growth factor family of receptors in preneoplasia and lung cancer: perspectives for targeted therapies.
  Journal
Lung Cancer 41 Suppl 1:S29-42 (2003)
DOI:10.1016/S0169-5002(03)00137-5
Reference
PMID:16112428
  Authors
Panani AD, Roussos C.
  Title
Cytogenetic and molecular aspects of lung cancer.
  Journal
Cancer Lett 239:1-9 (2006)
DOI:10.1016/j.canlet.2005.06.030
Reference
PMID:12407699
  Authors
Mitsuuchi Y, Testa JR.
  Title
Cytogenetics and molecular genetics of lung cancer.
  Journal
Am J Med Genet 115:183-8 (2002)
DOI:10.1002/ajmg.10692
Reference
PMID:15942304
  Authors
Breuer RH, Postmus PE, Smit EF.
  Title
Molecular pathology of non-small-cell lung cancer.
  Journal
Respiration 72:313-30 (2005)
DOI:10.1159/000085376
Reference
PMID:11895903
  Authors
Piyathilake CJ, Frost AR, Manne U, Weiss H, Bell WC, Heimburger DC, Grizzle WE.
  Title
Differential expression of growth factors in squamous cell carcinoma and precancerous lesions of the lung.
  Journal
Clin Cancer Res 8:734-44 (2002)
Reference
PMID:16189154
  Authors
Awaya H, Takeshima Y, Furonaka O, Kohno N, Inai K.
  Title
Gene amplification and protein expression of EGFR and HER2 by chromogenic in situ hybridisation and immunohistochemistry in atypical adenomatous hyperplasia and adenocarcinoma of the lung.
  Journal
J Clin Pathol 58:1076-80 (2005)
DOI:10.1136/jcp.2004.025585
Reference
PMID:21193867
  Authors
Lappano R, Maggiolini M
  Title
G protein-coupled receptors: novel targets for drug discovery in cancer.
  Journal
Nat Rev Drug Discov 10:47-60 (2011)
DOI:10.1038/nrd3320
Reference
PMID:24508914
  Authors
O'Hayre M, Degese MS, Gutkind JS
  Title
Novel insights into G protein and G protein-coupled receptor signaling in cancer.
  Journal
Curr Opin Cell Biol 27:126-35 (2014)
DOI:10.1016/j.ceb.2014.01.005
Reference
PMID:17251915
  Authors
Dorsam RT, Gutkind JS
  Title
G-protein-coupled receptors and cancer.
  Journal
Nat Rev Cancer 7:79-94 (2007)
DOI:10.1038/nrc2069
Related
pathway
panu03320  PPAR signaling pathway
panu04010  MAPK signaling pathway
panu04020  Calcium signaling pathway
panu04024  cAMP signaling pathway
panu04060  Cytokine-cytokine receptor interaction
panu04066  HIF-1 signaling pathway
panu04110  Cell cycle
panu04115  p53 signaling pathway
panu04150  mTOR signaling pathway
panu04151  PI3K-Akt signaling pathway
panu04210  Apoptosis
panu04310  Wnt signaling pathway
panu04330  Notch signaling pathway
panu04340  Hedgehog signaling pathway
panu04350  TGF-beta signaling pathway
panu04370  VEGF signaling pathway
panu04510  Focal adhesion
panu04512  ECM-receptor interaction
panu04520  Adherens junction
panu04630  JAK-STAT signaling pathway
panu04915  Estrogen signaling pathway
KO pathway
ko05200   
LinkDB

DBGET integrated database retrieval system