Entry
Name
Pathways in cancer - Ornithorhynchus anatinus (platypus)
Class
Human Diseases; Cancer: overview
BRITE hierarchy
Pathway map
Ortholog table
Organism
Ornithorhynchus anatinus (platypus) [GN:
oaa ]
Gene
100087013 BIRC5; baculoviral IAP repeat-containing protein 5 isoform X1 [KO:K08731 ]
100077194 LRP6; low-density lipoprotein receptor-related protein 6 [KO:K03068 ]
100091980 DVL3; segment polarity protein dishevelled homolog DVL-3 isoform X1 [KO:K02353 ]
100089867 DVL2; segment polarity protein dishevelled homolog DVL-2 [KO:K02353 ]
100681615 DVL1; segment polarity protein dishevelled homolog DVL-1 isoform X1 [KO:K02353 ]
100082592 GNA12; guanine nucleotide-binding protein subunit alpha-12 [KO:K04346 ]
103166871 GNA13; guanine nucleotide-binding protein subunit alpha-13 isoform X1 [KO:K04639 ]
100073922 ARHGEF12; rho guanine nucleotide exchange factor 12 isoform X1 [KO:K07532 ]
100078658 ARHGEF1; LOW QUALITY PROTEIN: rho guanine nucleotide exchange factor 1 [KO:K12330 ]
100088734 PLEKHG5; pleckstrin homology domain-containing family G member 5 isoform X1 [KO:K19464 ]
100075665 GNAI1; LOW QUALITY PROTEIN: guanine nucleotide-binding protein G(i) subunit alpha-1 [KO:K04630 ]
100089995 GNAI3; guanine nucleotide-binding protein G(i) subunit alpha-3 [KO:K04630 ]
100077742 GNAI2; guanine nucleotide-binding protein G(i) subunit alpha-2 isoform X1 [KO:K04630 ]
100075455 PTGER4; prostaglandin E2 receptor EP4 subtype isoform X1 [KO:K04261 ]
100080392 GNAS; guanine nucleotide-binding protein G(s) subunit alpha isoform X1 [KO:K04632 ]
100077049 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 [KO:K04536 ]
114807890 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 [KO:K04537 ]
100090311 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 [KO:K07825 ]
100073829 GNB4; guanine nucleotide-binding protein subunit beta-4 [KO:K04538 ]
100081114 GNB5; guanine nucleotide-binding protein subunit beta-5 [KO:K04539 ]
100084993 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 [KO:K07826 ]
100082845 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 [KO:K04540 ]
114805646 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 [KO:K04541 ]
100092247 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 [KO:K04542 ]
100076953 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 [KO:K04543 ]
100088135 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 [KO:K04544 ]
100081252 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 [KO:K04545 ]
114813799 guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11-like [KO:K04546 ]
100078907 GNG14; putative guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-14 [KO:K04347 ]
100081920 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 [KO:K04347 ]
100085219 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 [KO:K04547 ]
100077961 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1 [KO:K04548 ]
114815157 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 [KO:K04549 ]
100086270 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1 [KO:K00922 ] [EC:2.7.1.153 ]
100073788 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922 ] [EC:2.7.1.153 ]
100074273 PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1 [KO:K00922 ] [EC:2.7.1.153 ]
100080187 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta isoform X1 [KO:K02649 ]
100082075 PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1 [KO:K02649 ]
103167126 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha [KO:K02649 ]
100083819 NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1 [KO:K02580 ]
100079514 NFKB2; nuclear factor NF-kappa-B p100 subunit isoform X1 [KO:K04469 ]
100092915 STAT5B; LOW QUALITY PROTEIN: signal transducer and activator of transcription 5B [KO:K11224 ]
100080691 guanine nucleotide-binding protein G(q) subunit alpha isoform X1 [KO:K04634 ]
100084804 GNA11; guanine nucleotide-binding protein subunit alpha-11 isoform X1 [KO:K04635 ]
114808753 guanine nucleotide-binding protein subunit alpha-11-like [KO:K04635 ]
100078508 PLCB1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X1 [KO:K05858 ] [EC:3.1.4.11 ]
100084272 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 [KO:K05858 ] [EC:3.1.4.11 ]
103165385 IL2RA; interleukin-2 receptor subunit alpha isoform X2 [KO:K05068 ]
100093035 IL5RA; interleukin-5 receptor subunit alpha isoform X1 [KO:K05067 ]
100073530 IL6ST; interleukin-6 receptor subunit beta isoform X1 [KO:K05060 ]
100091982 EML4; echinoderm microtubule-associated protein-like 4 isoform X1 [KO:K15420 ]
100090421 RASGRP2; LOW QUALITY PROTEIN: RAS guanyl-releasing protein 2 [KO:K12361 ]
100087932 STAT3; signal transducer and activator of transcription 3 isoform X2 [KO:K04692 ]
100087266 STAT1; signal transducer and activator of transcription 1-alpha/beta isoform X1 [KO:K11220 ]
100087549 STAT2; signal transducer and activator of transcription 2 [KO:K11221 ]
100680834 STAT4; signal transducer and activator of transcription 4 isoform X1 [KO:K11222 ]
103171440 STAT6; signal transducer and activator of transcription 6 [KO:K11225 ]
100081033 PDGFA; platelet-derived growth factor subunit A isoform X1 [KO:K04359 ]
100075300 FGF3; LOW QUALITY PROTEIN: fibroblast growth factor 3 [KO:K04358 ]
100078239 RASSF1; ras association domain-containing protein 1 isoform X1 [KO:K09850 ]
100078757 PLCG1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1 [KO:K01116 ] [EC:3.1.4.11 ]
100089453 CAMK2G; calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X1 [KO:K04515 ] [EC:2.7.11.17 ]
100079279 CAMK2A; calcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1 [KO:K04515 ] [EC:2.7.11.17 ]
100074083 CAMK2D; calcium/calmodulin-dependent protein kinase type II subunit delta isoform X1 [KO:K04515 ] [EC:2.7.11.17 ]
100089905 CAMK2B; calcium/calmodulin-dependent protein kinase type II subunit beta isoform X1 [KO:K04515 ] [EC:2.7.11.17 ]
100080818 RALGDS; ral guanine nucleotide dissociation stimulator isoform X1 [KO:K08732 ]
100086186 CDC42; cell division control protein 42 homolog isoform X1 [KO:K04393 ]
100080852 PPARG; peroxisome proliferator-activated receptor gamma [KO:K08530 ]
100085678 PPARD; peroxisome proliferator-activated receptor delta isoform X1 [KO:K04504 ]
100075814 ZBTB16; zinc finger and BTB domain-containing protein 16 [KO:K10055 ]
100082553 RUNX1; runt-related transcription factor 1 isoform X1 [KO:K08367 ]
103171406 granulocyte-macrophage colony-stimulating factor receptor subunit alpha-like isoform X1 [KO:K05066 ]
103171402 granulocyte-macrophage colony-stimulating factor receptor subunit alpha-like [KO:K05066 ]
100080173 CSF3R; granulocyte colony-stimulating factor receptor [KO:K05061 ]
100076280 ZBTB17; zinc finger and BTB domain-containing protein 17 isoform X1 [KO:K10500 ]
100081893 GADD45A; growth arrest and DNA damage-inducible protein GADD45 alpha [KO:K04402 ]
100091078 MITF; microphthalmia-associated transcription factor isoform X1 [KO:K09455 ]
100080176 TGFB2; transforming growth factor beta-2 proprotein isoform X1 [KO:K13376 ]
100085963 SMAD3; mothers against decapentaplegic homolog 3 isoform X1 [KO:K23605 ]
100081646 FASLG; tumor necrosis factor ligand superfamily member 6 [KO:K04389 ]
103165091 FAS; tumor necrosis factor receptor superfamily member 6 isoform X1 [KO:K04390 ]
114810052 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1 [KO:K10131 ]
100073402 APAF1; apoptotic protease-activating factor 1 isoform X1 [KO:K02084 ]
100084872 NFE2L2; nuclear factor erythroid 2-related factor 2 isoform X1 [KO:K05638 ]
114806529 VHL; von Hippel-Lindau disease tumor suppressor isoform X1 [KO:K03871 ]
100091752 EPAS1; LOW QUALITY PROTEIN: endothelial PAS domain-containing protein 1 [KO:K09095 ]
100088277 ARNT; aryl hydrocarbon receptor nuclear translocator isoform X1 [KO:K09097 ]
100092280 ARNT2; aryl hydrocarbon receptor nuclear translocator 2 isoform X3 [KO:K15589 ]
100074548 SLC2A1; solute carrier family 2, facilitated glucose transporter member 1 isoform X1 [KO:K07299 ]
100092718 NOTCH1; neurogenic locus notch homolog protein 1 isoform X2 [KO:K02599 ]
100081510 NOTCH2; LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 2 [KO:K20994 ]
100085220 HEYL; hairy/enhancer-of-split related with YRPW motif-like protein [KO:K09091 ]
100093073 HEY1; hairy/enhancer-of-split related with YRPW motif protein 1 [KO:K09091 ]
100092155 HEY2; hairy/enhancer-of-split related with YRPW motif protein 2 isoform X1 [KO:K09091 ]
100075383 GLI3; LOW QUALITY PROTEIN: transcriptional activator GLI3 [KO:K06230 ]
Compound
C00681 1-Acyl-sn-glycerol 3-phosphate
C01245 D-myo-Inositol 1,4,5-trisphosphate
C05981 Phosphatidylinositol-3,4,5-trisphosphate
C16038 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
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oaa04060 Cytokine-cytokine receptor interaction
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