Enzymes

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 1. Oxidoreductases
   1.1  Acting on the CH-OH group of donors
   1.2  Acting on the aldehyde or oxo group of donors
   1.3  Acting on the CH-CH group of donors
     1.3.1  With NAD+ or NADP+ as acceptor
     1.3.2  With a cytochrome as acceptor
     1.3.3  With oxygen as acceptor
     1.3.4  With a disulfide as acceptor
     1.3.5  With a quinone or related compound as acceptor
       1.3.5.1  succinate dehydrogenase
         K00233  frdA, fdrA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1 7.1.1.12]
         K00234  SDHA, SDH1; succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:1.3.5.1]
         K00235  SDHB, SDH2; succinate dehydrogenase (ubiquinone) iron-sulfur subunit [EC:1.3.5.1]
         K00239  sdhA, frdA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
         K00240  sdhB, frdB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
         K00244  frdA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
         K00245  frdB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
         K25995  frdB, fdrB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1 7.1.1.12]
       1.3.5.2  dihydroorotate dehydrogenase (quinone)
         K00254  DHODH, pyrD; dihydroorotate dehydrogenase [EC:1.3.5.2]
       1.3.5.3  protoporphyrinogen IX dehydrogenase (quinone)
         K00230  hemG; menaquinone-dependent protoporphyrinogen oxidase [EC:1.3.5.3]
       1.3.5.5  15-cis-phytoene desaturase
         K02293  PDS, crtP; 15-cis-phytoene desaturase [EC:1.3.5.5]
       1.3.5.6  9,9'-dicis-zeta-carotene desaturase
         K00514  ZDS, crtQ; zeta-carotene desaturase [EC:1.3.5.6]
     1.3.7  With an iron-sulfur protein as acceptor
     1.3.8  With a flavin as acceptor
     1.3.98  With other, known, physiological acceptors
     1.3.99  With unknown physiological acceptors
   1.4  Acting on the CH-NH2 group of donors
   1.5  Acting on the CH-NH group of donors
   1.6  Acting on NADH or NADPH
   1.7  Acting on other nitrogenous compounds as donors
   1.8  Acting on a sulfur group of donors
   1.9  Acting on a heme group of donors
   1.10  Acting on diphenols and related substances as donors
     1.10.1  With NAD+ or NADP+ as acceptor
     1.10.3  With oxygen as acceptor
     1.10.5  With a quinone or related compound as acceptor
       1.10.5.1  ribosyldihydronicotinamide dehydrogenase (quinone)
         K08071  NQO2; ribosyldihydronicotinamide dehydrogenase (quinone) [EC:1.10.5.1]
   1.11  Acting on a peroxide as acceptor
   1.12  Acting on hydrogen as donor
   1.13  Acting on single donors with incorporation of molecular oxygen (oxygenases)
   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.15  Acting on superoxide as acceptor
   1.16  Oxidizing metal ions
   1.17  Acting on CH or CH2 groups
   1.18  Acting on iron-sulfur proteins as donors
   1.19  Acting on reduced flavodoxin as donor
   1.20  Acting on phosphorus or arsenic in donors
   1.21  Catalysing the reaction X-H + Y-H = X-Y
   1.23  Reducing C-O-C group as acceptor
   1.97  Other oxidoreductases
 
 2. Transferases
   2.1  Transferring one-carbon groups
     2.1.1  Methyltransferases
     2.1.2  Hydroxymethyl-, formyl- and related transferases
       2.1.2.1  glycine hydroxymethyltransferase
         K00600  glyA, SHMT; glycine hydroxymethyltransferase [EC:2.1.2.1]
       2.1.2.2  phosphoribosylglycinamide formyltransferase 1
         K00601  E2.1.2.2; phosphoribosylglycinamide formyltransferase [EC:2.1.2.2]
         K01492  purNH; phosphoribosylglycinamide/phosphoribosylaminoimidazolecarboxamide formyltransferase [EC:2.1.2.2 2.1.2.3]
         K11175  purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2]
         K11787  GART; phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.4.13 2.1.2.2 6.3.3.1]
       2.1.2.3  phosphoribosylaminoimidazolecarboxamide formyltransferase
         K00602  purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
         K01492  purNH; phosphoribosylglycinamide/phosphoribosylaminoimidazolecarboxamide formyltransferase [EC:2.1.2.2 2.1.2.3]
       2.1.2.4  glycine formimidoyltransferase
       2.1.2.5  glutamate formimidoyltransferase
         K00603  fctD; glutamate formiminotransferase / 5-formyltetrahydrofolate cyclo-ligase [EC:2.1.2.5 6.3.3.2]
         K13990  FTCD; glutamate formiminotransferase / formiminotetrahydrofolate cyclodeaminase [EC:2.1.2.5 4.3.1.4]
       2.1.2.7  D-alanine 2-hydroxymethyltransferase
       2.1.2.8  deoxycytidylate 5-hydroxymethyltransferase
         K19796  gp42; Straboviridae dCMP hydroxymethylase [EC:2.1.2.8]
       2.1.2.9  methionyl-tRNA formyltransferase
         K00604  MTFMT, fmt; methionyl-tRNA formyltransferase [EC:2.1.2.9]
       2.1.2.10  aminomethyltransferase
         K00605  gcvT, AMT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
       2.1.2.11  3-methyl-2-oxobutanoate hydroxymethyltransferase
         K00606  panB; 3-methyl-2-oxobutanoate hydroxymethyltransferase [EC:2.1.2.11]
       2.1.2.13  UDP-4-amino-4-deoxy-L-arabinose formyltransferase
         K10011  arnA, pmrI; UDP-4-amino-4-deoxy-L-arabinose formyltransferase / UDP-glucuronic acid dehydrogenase (UDP-4-keto-hexauronic acid decarboxylating) [EC:2.1.2.13 1.1.1.305]
       2.1.2.14  GDP-perosamine N-formyltransferase
         K00607  wbkC; GDP-perosamine N-formyltransferase [EC:2.1.2.14]
     2.1.3  Carboxy- and carbamoyltransferases
     2.1.4  Amidinotransferases
     2.1.5  Methylenetransferases
   2.2  Transferring aldehyde or ketonic groups
   2.3  Acyltransferases
     2.3.1  Transferring groups other than aminoacyl groups
     2.3.2  Aminoacyltransferases
       2.3.2.1  D-glutamyltransferase
       2.3.2.2  gamma-glutamyltransferase
       2.3.2.3  lysyltransferase
       2.3.2.5  glutaminyl-peptide cyclotransferase
       2.3.2.6  lysine/arginine leucyltransferase
       2.3.2.7  aspartyltransferase
       2.3.2.8  arginyltransferase
       2.3.2.9  agaritine gamma-glutamyltransferase
       2.3.2.10  UDP-N-acetylmuramoylpentapeptide-lysine N6-alanyltransferase
       2.3.2.11  alanylphosphatidylglycerol synthase
       2.3.2.12  peptidyltransferase
       2.3.2.13  protein-glutamine gamma-glutamyltransferase
       2.3.2.14  D-alanine gamma-glutamyltransferase
       2.3.2.15  glutathione gamma-glutamylcysteinyltransferase
       2.3.2.16  lipid II:glycine glycyltransferase
       2.3.2.17  N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-(N6-glycyl)-D-alanyl-D-alanine-diphosphoundecaprenyl-N-acetylglucosamine:glycine glycyltransferase
       2.3.2.18  N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-(N6-triglycine)-D-alanyl-D-alanine-diphosphoundecaprenyl-N-acetylglucosamine:glycine glycyltransferase
       2.3.2.19  ribostamycin 4-(gamma-L-glutamylamino)-(S)-2-hydroxybutanoate transferase
       2.3.2.20  cyclo(L-leucyl-L-phenylalanyl) synthase
       2.3.2.21  cyclo(L-tyrosyl-L-tyrosyl) synthase
       2.3.2.22  cyclo(L-leucyl-L-leucyl) synthase
       2.3.2.23  E2 ubiquitin-conjugating enzyme
       2.3.2.24  (E3-independent) E2 ubiquitin-conjugating enzyme
       2.3.2.25  N-terminal E2 ubiquitin-conjugating enzyme
       2.3.2.26  HECT-type E3 ubiquitin transferase
       2.3.2.27  RING-type E3 ubiquitin transferase
         K01931  NEUR; protein neuralized [EC:2.3.2.27]
         K03173  TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
         K03175  TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
         K04506  SIAH1; E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]
         K04707  CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
         K04725  XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
         K06058  DTX; deltex [EC:2.3.2.27]
         K06643  MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
         K06664  PEX2, PXMP3; peroxin-2 [EC:2.3.2.27 2.3.2.36]
         K07963  TRIM23, ARFD1; tripartite motif-containing protein 23 [EC:2.3.2.27]
         K08285  TRIM18, MID1; midline 1 [EC:2.3.2.27]
         K08742  SIAH2; E3 ubiquitin-protein ligase SIAH2 [EC:2.3.2.27]
         K08881  TRIM24, TIF1A; tripartite motif-containing protein 24 [EC:2.3.2.27]
         K08882  TRIM28, TIF1B; tripartite motif-containing protein 28 [EC:2.3.2.27]
         K08883  TRIM33, TIF1G; tripartite motif-containing protein 33 [EC:2.3.2.27]
         K09561  STUB1, CHIP; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]
         K10143  RFWD2, COP1; E3 ubiquitin-protein ligase RFWD2 [EC:2.3.2.27]
         K10144  RCHY1, PIRH2; RING finger and CHY zinc finger domain-containing protein 1 [EC:2.3.2.27]
         K10596  UBE4A; ubiquitin conjugation factor E4 A [EC:2.3.2.27]
         K10597  UBE4B, UFD2; ubiquitin conjugation factor E4 B [EC:2.3.2.27]
         K10599  PRPF19, PRP19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
         K10600  UBOX5, UIP5; U-box domain-containing protein 5 [EC:2.3.2.27]
         K10601  SYVN1, HRD1; E3 ubiquitin-protein ligase synoviolin [EC:2.3.2.27]
         K10602  NHLRC1; E3 ubiquitin-protein ligase NHLRC1 [EC:2.3.2.27]
         K10604  MGRN1; E3 ubiquitin-protein ligase MGRN1 [EC:2.3.2.27]
         K10605  BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
         K10606  FANCL, PHF9; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]
         K10607  TRIM32, HT2A; tripartite motif-containing protein 32 [EC:2.3.2.27]
         K10608  TRIM37, MUL; tripartite motif-containing protein 37 [EC:2.3.2.27]
         K10624  RBBP6; E3 ubiquitin-protein ligase RBBP6 [EC:2.3.2.27]
         K10625  UBR1; E3 ubiquitin-protein ligase UBR1 [EC:2.3.2.27]
         K10626  UBR2; E3 ubiquitin-protein ligase UBR2 [EC:2.3.2.27]
         K10627  RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]
         K10628  RAG1; V(D)J recombination-activating protein 1 [EC:2.3.2.27]
         K10629  RNF128, GRAIL; E3 ubiquitin-protein ligase RNF128 [EC:2.3.2.27]
         K10631  TOPORS; E3 ubiquitin-protein ligase Topors [EC:2.3.2.27]
         K10632  BRAP; BRCA1-associated protein [EC:2.3.2.27]
         K10633  PJA1; E3 ubiquitin-protein ligase Praja1 [EC:2.3.2.27]
         K10634  PJA2; E3 ubiquitin-protein ligase Praja2 [EC:2.3.2.27]
         K10635  RNF111; E3 ubiquitin-protein ligase Arkadia [EC:2.3.2.27]
         K10637  MYLIP, MIR; E3 ubiquitin-protein ligase MYLIP [EC:2.3.2.27]
         K10638  UHRF1, NP95; E3 ubiquitin-protein ligase UHRF1 [EC:2.3.2.27]
         K10639  CCNB1IP1, HEI10; E3 ubiquitin-protein ligase CCNP1IP1 [EC:2.3.2.27]
         K10640  RNF25, AO7; E3 ubiquitin-protein ligase RNF25 [EC:2.3.2.27]
         K10641  LRSAM1; E3 ubiquitin-protein ligase LRSAM1 [EC:2.3.2.27]
         K10642  DZIP3; E3 ubiquitin-protein ligase DZIP3 [EC:2.3.2.27]
         K10643  CNOT4, NOT4, MOT2; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
         K10644  CHFR; E3 ubiquitin-protein ligase CHFR [EC:2.3.2.27]
         K10645  MIB; E3 ubiquitin-protein ligase mind-bomb [EC:2.3.2.27]
         K10646  TRAF7, RFWD1; E3 ubiquitin-protein ligase TRAF7 [EC:2.3.2.27]
         K10647  TRIM1, MID2; midline 2 [EC:2.3.2.27]
         K10648  TRIM5; tripartite motif-containing protein 5 [EC:2.3.2.27]
         K10650  TRIM11; tripartite motif-containing protein 11 [EC:2.3.2.27]
         K10651  TRIM21, SSA1; tripartite motif-containing protein 21 [EC:2.3.2.27]
         K10652  TRIM25, EFP; tripartite motif-containing protein 25 [EC:2.3.2.27]
         K10655  TRIM63, MURF1; tripartite motif-containing protein 63 [EC:2.3.2.27]
         K10656  MARCH1_8; E3 ubiquitin-protein ligase MARCH1/8 [EC:2.3.2.27]
         K10657  MARCH2_3; E3 ubiquitin-protein ligase MARCH2/3 [EC:2.3.2.27]
         K10659  MARCH4_9_11; E3 ubiquitin-protein ligase MARCH4/9/11 [EC:2.3.2.27]
         K10660  MARCH5; E3 ubiquitin-protein ligase MARCH5 [EC:2.3.2.27]
         K10661  MARCH6, DOA10; E3 ubiquitin-protein ligase MARCH6 [EC:2.3.2.27]
         K10662  MARCH7, AXOT; E3 ubiquitin-protein ligase MARCH7 [EC:2.3.2.27]
         K10663  ATL4; E3 ubiquitin-protein ligase ATL4 [EC:2.3.2.27]
         K10664  ATL6S; E3 ubiquitin-protein ligase ATL6/9/15/31/42/55 [EC:2.3.2.27]
         K10665  MARCH10; E3 ubiquitin-protein ligase MARCH10 [EC:2.3.2.27]
         K10666  RNF5_185; E3 ubiquitin-protein ligase RNF5/185 [EC:2.3.2.27]
         K10667  RNF8; E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27]
         K10668  RNF138; E3 ubiquitin-protein ligase RNF138 [EC:2.3.2.27]
         K10691  UBR4, ZUBR1; E3 ubiquitin-protein ligase UBR4 [EC:2.3.2.27]
         K10692  LNX1_2; ligand of Numb protein X 1/2 [EC:2.3.2.27]
         K10694  ZNRF1_2; E3 ubiquitin-protein ligase ZNRF1/2 [EC:2.3.2.27]
         K10695  RNF1_2; E3 ubiquitin-protein ligase RNF1/2 [EC:2.3.2.27]
         K10696  BRE1; E3 ubiquitin-protein ligase BRE1 [EC:2.3.2.27]
         K11964  PELI; pellino [EC:2.3.2.27]
         K11978  UBR3; E3 ubiquitin-protein ligase UBR3 [EC:2.3.2.27]
         K11979  UBR7; E3 ubiquitin-protein ligase UBR7 [EC:2.3.2.27]
         K11981  RNF41, NRDP1; E3 ubiquitin-protein ligase NRDP1 [EC:2.3.2.27]
         K11982  RNF115_126; E3 ubiquitin-protein ligase RNF115/126 [EC:2.3.2.27]
         K11983  RNF182; E3 ubiquitin-protein ligase RNF182 [EC:2.3.2.27]
         K11985  TRAIP, TRIP; TRAF-interacting protein [EC:2.3.2.27]
         K11998  TRIM4; tripartite motif-containing protein 4 [EC:2.3.2.27]
         K12001  TRIM8; tripartite motif-containing protein 8 [EC:2.3.2.27]
         K12003  TRIM13; tripartite motif-containing protein 13 [EC:2.3.2.27]
         K12006  TRIM16; tripartite motif-containing protein 16 [EC:2.3.2.27]
         K12007  TRIM17; tripartite motif-containing protein 17 [EC:2.3.2.27]
         K12009  TRIM27, RFP; tripartite motif-containing protein 27 [EC:2.3.2.27]
         K12011  TRIM31; tripartite motif-containing protein 31 [EC:2.3.2.27]
         K12013  TRIM36; tripartite motif-containing protein 36 [EC:2.3.2.27]
         K12014  TRIM38; tripartite motif-containing protein 38 [EC:2.3.2.27]
         K12015  TRIM39, BTR; tripartite motif-containing protein 39 / bloodthirsty-related gene family protein [EC:2.3.2.27]
         K12017  TRIM41; tripartite motif-containing protein 41 [EC:2.3.2.27]
         K12026  TRIM56; tripartite motif-containing protein 56 [EC:2.3.2.27]
         K12027  TRIM58; tripartite motif-containing protein 58 [EC:2.3.2.27]
         K12030  TRIM62; tripartite motif-containing protein 62 [EC:2.3.2.27]
         K12033  TRIM68; tripartite motif-containing protein 68 [EC:2.3.2.27]
         K12034  TRIM69; tripartite motif-containing protein 69 [EC:2.3.2.27]
         K12035  TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
         K12169  KPC1, RNF123; Kip1 ubiquitination-promoting complex protein 1 [EC:2.3.2.27]
         K12170  RNF125; E3 ubiquitin-protein ligase RNF125 [EC:2.3.2.27]
         K12171  SH3RF, POSH; E3 ubiquitin-protein ligase SH3RF [EC:2.3.2.27]
         K13346  PEX10; peroxin-10 [EC:2.3.2.27]
         K15682  PDZRN3_4, LNX3_4; ligand of Numb protein X 3/4 [EC:2.3.2.27]
         K15685  CBLL1; E3 ubiquitin-protein ligase Hakai [EC:2.3.2.27]
         K15686  MEX3, RKHD; RNA-binding protein MEX3 [EC:2.3.2.27]
         K15687  MKRN; E3 ubiquitin-protein ligase makorin [EC:2.3.2.27]
         K15688  MUL1; E3 ubiquitin-protein ligase MUL1 [EC:2.3.2.27]
         K15689  NEURL3, LINCR; E3 ubiquitin-protein ligase NEURL3 [EC:2.3.2.27]
         K15691  RFWD3; E3 ubiquitin-protein ligase RFWD3 [EC:2.3.2.27]
         K15692  RNF13, RZF; E3 ubiquitin-protein ligase RNF13 [EC:2.3.2.27]
         K15693  RNF26; E3 ubiquitin-protein ligase RNF26 [EC:2.3.2.27]
         K15694  RNF43; E3 ubiquitin-protein ligase RNF43 [EC:2.3.2.27]
         K15695  RNF103, KF1; E3 ubiquitin-protein ligase RNF103 [EC:2.3.2.27]
         K15697  RNF114; E3 ubiquitin-protein ligase RNF114 [EC:2.3.2.27]
         K15700  RNF146; E3 ubiquitin-protein ligase RNF146 [EC:2.3.2.27]
         K15701  RNF130, GOLIATH; E3 ubiquitin-protein ligase RNF130 [EC:2.3.2.27]
         K15702  RNF133; E3 ubiquitin-protein ligase RNF133 [EC:2.3.2.27]
         K15703  RNF139, TRC8; E3 ubiquitin-protein ligase RNF139 [EC:2.3.2.27]
         K15704  RNF149; E3 ubiquitin-protein ligase RNF149 [EC:2.3.2.27]
         K15705  RNF152; E3 ubiquitin-protein ligase RNF152 [EC:2.3.2.27]
         K15706  RNF167; E3 ubiquitin-protein ligase RNF167 [EC:2.3.2.27]
         K15707  RNF170; E3 ubiquitin-protein ligase RNF170 [EC:2.3.2.27]
         K15708  RNF180; E3 ubiquitin-protein ligase RNF180 [EC:2.3.2.27]
         K15709  RNF187; E3 ubiquitin-protein ligase RNF187 [EC:2.3.2.27]
         K15710  SHPRH; E3 ubiquitin-protein ligase SHPRH [EC:5.6.2.- 2.3.2.27]
         K15711  SMARCA3, HLTF; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]
         K15712  TTC3; E3 ubiquitin-protein ligase TTC3 [EC:2.3.2.27]
         K15713  UHRF2, NIRF; E3 ubiquitin-protein ligase UHRF2 [EC:2.3.2.27]
         K15714  ZNF645; E3 ubiquitin-protein ligase ZNF645 [EC:2.3.2.27]
         K15715  ZNRF4; E3 ubiquitin-protein ligase ZNRF4 [EC:2.3.2.27]
         K15716  ZSWIM2; E3 ubiquitin-protein ligase ZSWIM2 [EC:2.3.2.27]
         K16065  PIAS4; E3 SUMO-protein ligase PIAS4 [EC:2.3.2.27]
         K16271  RLIM, RNF12; E3 ubiquitin-protein ligase RLIM [EC:2.3.2.27]
         K16272  RNF135; E3 ubiquitin-protein ligase RNF135 [EC:2.3.2.27]
         K16273  ZNRF3; E3 ubiquitin-protein ligase ZNRF3 [EC:2.3.2.27]
         K16274  AIP2; E3 ubiquitin-protein ligase AIP2 [EC:2.3.2.27]
         K16275  BAH, NLA; E3 ubiquitin-protein ligase BAH [EC:2.3.2.27]
         K16277  DRIP; E3 ubiquitin-protein ligase DRIP [EC:2.3.2.27]
         K16278  HOS1; E3 ubiquitin-protein ligase HOS1 [EC:2.3.2.27]
         K16279  KEG; E3 ubiquitin-protein ligase KEG [EC:2.7.11.1 2.3.2.27]
         K16280  RGLG; E3 ubiquitin-protein ligase RGLG [EC:2.3.2.27]
         K16282  RHA2; E3 ubiquitin-protein ligase RHA2 [EC:2.3.2.27]
         K16283  SDIR1; E3 ubiquitin-protein ligase SDIR1 [EC:2.3.2.27]
         K16284  SIS3; E3 ubiquitin-protein ligase SIS3 [EC:2.3.2.27]
         K16285  XERICO; RING/U-box domain-containing protein [EC:2.3.2.27]
         K16286  EL5; E3 ubiquitin-protein ligase EL5 [EC:2.3.2.27]
         K17044  RNF166; E3 ubiquitin-protein ligase RNF166 [EC:2.3.2.27]
         K17821  RNF165; E3 ubiquitin-protein ligase RNF165 [EC:2.3.2.27]
         K19037  ATL23; E3 ubiquitin-protein ligase ATL23 [EC:2.3.2.27]
         K19038  ATL41; E3 ubiquitin-protein ligase ATL41 [EC:2.3.2.27]
         K19039  ATL7_58_59; E3 ubiquitin-protein ligase ATL7/58/59 [EC:2.3.2.27]
         K19040  ATL76S; E3 ubiquitin-protein ligase ATL10/75/76/77/78 [EC:2.3.2.27]
         K19041  RNF38_44; E3 ubiquitin-protein ligase RNF38/44 [EC:2.3.2.27]
         K19042  BOI; E3 ubiquitin-protein ligase BOI and related proteins [EC:2.3.2.27]
         K19043  RHF; E3 ubiquitin-protein ligase RHF [EC:2.3.2.27]
         K19044  XBAT32_33; E3 ubiquitin-protein ligase XBAT32/33 [EC:2.3.2.27]
         K19045  BB; E3 ubiquitin-protein ligase BIG BROTHER and related proteins [EC:2.3.2.27]
         K21504  IAP3; Baculoviridae E3 ubiquitin-protein ligase [EC:2.3.2.27]
         K21920  KCTD11; BTB/POZ domain-containing protein KCTD11 [EC:2.3.2.27]
         K22155  JADE2; E3 ubiquitin-protein ligase Jade-2 [EC:2.3.2.27]
         K22375  DCST1; E3 ubiquitin-protein ligase DCST1 [EC:2.3.2.27]
         K22376  KCMF1, FIGC; E3 ubiquitin-protein ligase KCMF1 [EC:2.3.2.27]
         K22377  LTN1; E3 ubiquitin-protein ligase listerin [EC:2.3.2.27]
         K22378  RNF181; E3 ubiquitin-protein ligase RNF181 [EC:2.3.2.27]
         K22379  RNFT1; E3 ubiquitin-protein ligase RNFT1 [EC:2.3.2.27]
         K22380  TMEM129; E3 ubiquitin-protein ligase TM129 [EC:2.3.2.27]
         K22381  ZNF598; E3 ubiquitin-protein ligase ZNF598 [EC:2.3.2.27]
         K22401  E4F1; transcription factor E4F1 / E3 ubiquitin-protein ligase [EC:2.3.2.27]
         K22517  CBLB; E3 ubiquitin-protein ligase CBL-B [EC:2.3.2.27]
         K22518  CBLC; E3 ubiquitin-protein ligase CBL-C [EC:2.3.2.27]
         K22645  SLX5; E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX5 [EC:2.3.2.27]
         K22646  SLX8; E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX8 [EC:2.3.2.27]
         K22651  RNF4; E3 ubiquitin-protein ligase RNF4 [EC:2.3.2.27]
         K22753  RNF6; E3 ubiquitin-protein ligase RNF6 [EC:2.3.2.27]
         K22754  RNF213; E3 ubiquitin-protein ligase RNF213 [EC:2.3.2.27]
         K22817  NSMCE1, NSE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]
         K23047  UNKL; E3 ubiquitin-protein ligase UNKL [EC:2.3.2.27]
         K23333  RMND5; E3 ubiquitin-protein transferase RMND5 [EC:2.3.2.27]
         K23787  DMA1_2; E3 ubiquitin-protein ligase DMA1/2 [EC:2.3.2.27]
         K23788  TUL1, FLY1_2; transmembrane E3 ubiquitin-protein ligase [EC:2.3.2.27]
         K23789  RNF145; E3 ubiquitin-protein ligase RNF145 [EC:2.3.2.27]
         K23828  ipaH1.4_2.5; E3 ubiquitin-protein ligase IpaH1.4/2.5 [EC:2.3.2.27]
         K23830  ipaH4.5; E3 ubiquitin-protein ligase IpaH4.5 [EC:2.3.2.27]
         K23831  ipaH0722; E3 ubiquitin-protein ligase IpaH0722 [EC:2.3.2.27]
         K23834  ipaH7.8; E3 ubiquitin-protein ligase IpaH7.8 [EC:2.3.2.27]
         K23946  slrP; E3 ubiquitin-protein ligase SlrP [EC:2.3.2.27]
         K24091  OBI1; ORC ubiquitin ligase 1 [EC:2.3.2.27]
         K25173  RNF112; E3 ubiquitin-protein ligase RNF112 [EC:2.3.2.27]
         K25174  RNF220; E3 ubiquitin-protein ligase RNF220 [EC:2.3.2.27]
         K25175  ZFP91; E3 ubiquitin-protein ligase ZFP91 [EC:2.3.2.27]
         K25192  RNF157; E3 ubiquitin-protein ligase RNF157 [EC:2.3.2.27]
         K25214  RNF186; E3 ubiquitin-protein ligase RNF186 [EC:2.3.2.27]
         K25840  AIRP2; E3 ubiquitin-protein ligase AIRP2 [EC:2.3.2.27]
         K26452  IE2; Alphabaculovirus E3 ubiquitin-protein ligase IE2 [EC:2.3.2.27]
         K26506  p28; Orthopoxvirus E3 ubiquitin-protein ligase p28 [EC:2.3.2.27]
         K26509  ORF63; Equid alphaherpesvirus E3 ubiquitin-protein ligase ICP0 [EC:2.3.2.27]
         K26516  LAP; Leporipoxvirus E3 ubiquitin-protein ligase LAP [EC:2.3.2.27]
         K26979  RNF10; E3 ubiquitin-protein ligase RNF10 [EC:2.3.2.27]
         K27504  LOG2; E3 ubiquitin-protein ligase LOG2 [EC:2.3.2.27]
         K27628  PUB12_13_14; U-box domain-containing protein 12/13/14 [EC:2.3.2.27]
         K27970  PUB2S; U-box gene family group I [EC:2.3.2.27]
         K28412  PUB42_43_44; U-box domain-containing protein 42/43/44 [EC:2.3.2.27]
         K28593  RFI2; E3 ubiquitin-protein ligase RFI2 and related proteins [EC:2.3.2.27]
       2.3.2.28  L-allo-isoleucyltransferase
       2.3.2.29  aspartate/glutamate leucyltransferase
       2.3.2.30  L-ornithine Nalpha-acyltransferase
       2.3.2.31  RBR-type E3 ubiquitin transferase
       2.3.2.32  cullin-RING-type E3 NEDD8 transferase
       2.3.2.33  RCR-type E3 ubiquitin transferase
       2.3.2.34  E2 NEDD8-conjugating enzyme
       2.3.2.35  capsaicin synthase
       2.3.2.36  RING-type E3 ubiquitin transferase (cysteine targeting)
       2.3.2.37  ergosteryl-3beta-O-L-aspartate synthase
       2.3.2.38  (sulfonamide-N)(L-isoleucyl)altemicidin (3R)-3-methyl-L-phenylalanyltransferase
       2.3.2.39  altemicidin L-isoleucyltransferase
     2.3.3  Acyl groups converted into alkyl groups on transfer
   2.4  Glycosyltransferases
   2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.6  Transferring nitrogenous groups
   2.7  Transferring phosphorus-containing groups
     2.7.1  Phosphotransferases with an alcohol group as acceptor
     2.7.2  Phosphotransferases with a carboxy group as acceptor
     2.7.3  Phosphotransferases with a nitrogenous group as acceptor
     2.7.4  Phosphotransferases with a phosphate group as acceptor
     2.7.6  Diphosphotransferases
       2.7.6.1  ribose-phosphate diphosphokinase
       2.7.6.2  thiamine diphosphokinase
       2.7.6.3  2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase
       2.7.6.4  nucleotide diphosphokinase
       2.7.6.5  GTP diphosphokinase
         K00951  relA; GTP pyrophosphokinase [EC:2.7.6.5]
         K01139  spoT; GTP diphosphokinase / guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2]
         K07816  E2.7.6.5; GTP pyrophosphokinase [EC:2.7.6.5]
     2.7.7  Nucleotidyltransferases
     2.7.8  Transferases for other substituted phosphate groups
     2.7.9  Phosphotransferases with paired acceptors
     2.7.10  Protein-tyrosine kinases
       2.7.10.1  receptor protein-tyrosine kinase
         K03176  NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
         K04360  NTRK2, TRKB; neurotrophic tyrosine kinase receptor type 2 [EC:2.7.10.1]
         K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
         K04362  FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
         K04363  PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
         K04527  INSR, CD220; insulin receptor [EC:2.7.10.1]
         K05083  ERBB2, HER2, CD340; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
         K05084  ERBB3, HER3; receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1]
         K05085  ERBB4, HER4; receptor tyrosine-protein kinase erbB-4 [EC:2.7.10.1]
         K05086  INSRR; insulin receptor-related receptor [EC:2.7.10.1]
         K05087  IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
         K05088  ROS1; proto-oncogene tyrosine-protein kinase ROS [EC:2.7.10.1]
         K05089  PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
         K05090  CSF1R, FMS, CD115; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
         K05091  KIT, SCFR, CD117; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
         K05092  FLT3, FLK2, CD135; fms-related tyrosine kinase 3 [EC:2.7.10.1]
         K05093  FGFR2, CD332; fibroblast growth factor receptor 2 [EC:2.7.10.1]
         K05094  FGFR3, CD333; fibroblast growth factor receptor 3 [EC:2.7.10.1]
         K05095  FGFR4, CD334; fibroblast growth factor receptor 4 [EC:2.7.10.1]
         K05096  FLT1, VEGFR1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
         K05097  FLT4, VEGFR3; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
         K05098  KDR, VEGFR2, CD309; kinase insert domain protein receptor [EC:2.7.10.1]
         K05099  MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
         K05100  MST1R, RON, CD136; macrophage-stimulating 1 receptor [EC:2.7.10.1]
         K05101  NTRK3, TRKC; neurotrophic tyrosine kinase, receptor type 3 [EC:2.7.10.1]
         K05102  EPHA1, EPH; Eph receptor A1 [EC:2.7.10.1]
         K05103  EPHA2, ECK; Eph receptor A2 [EC:2.7.10.1]
         K05104  EPHA3, HEK, TYRO4; Eph receptor A3 [EC:2.7.10.1]
         K05105  EPHA4, SEK, TYRO1; Eph receptor A4 [EC:2.7.10.1]
         K05106  EPHA5, EHK1, TYRO4; Eph receptor A5 [EC:2.7.10.1]
         K05107  EPHA6, EHK2; Eph receptor A6 [EC:2.7.10.1]
         K05108  EPHA7, EHK3, HEK11; EphA7 [EC:2.7.10.1]
         K05109  EPHA8, EEK; Eph receptor A8 [EC:2.7.10.1]
         K05110  EPHB1, ELK, NET; Eph receptor B1 [EC:2.7.10.1]
         K05111  EPHB2, ERK, DRT; Eph receptor B2 [EC:2.7.10.1]
         K05112  EPHB3, HEK2, ETK2; Eph receptor B3 [EC:2.7.10.1]
         K05113  EPHB4, HTK; Eph receptor B4 [EC:2.7.10.1]
         K05114  EPHB6; Eph receptor B6 [EC:2.7.10.1]
         K05115  AXL, UFO; AXL receptor tyrosine kinase [EC:2.7.10.1]
         K05116  TYRO3, RSE; TYRO3 protein tyrosine kinase 3 [EC:2.7.10.1]
         K05117  MERTK, MER; c-mer proto-oncogene tyrosine kinase [EC:2.7.10.1]
         K05118  LTK; leukocyte tyrosine kinase [EC:2.7.10.1]
         K05119  ALK, CD246; anaplastic lymphoma kinase [EC:2.7.10.1]
         K05120  TIE1; tyrosine kinase receptor 1 [EC:2.7.10.1]
         K05121  TEK, TIE2, CD202; endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]
         K05122  ROR1, NTRKR1; receptor tyrosine kinase-like orphan receptor 1 [EC:2.7.10.1]
         K05123  ROR2, NTRKR2; receptor tyrosine kinase-like orphan receptor 2 [EC:2.7.10.1]
         K05124  DDR1, NEP, CD167a; discoidin domain receptor family member 1 [EC:2.7.10.1]
         K05125  DDR2, TKT, CD167b; discoidin domain receptor family member 2 [EC:2.7.10.1]
         K05126  RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
         K05127  PTK7, CCK4; PTK7 protein tyrosine kinase 7 [EC:2.7.10.1]
         K05128  RYK; RYK receptor-like tyrosine kinase [EC:2.7.10.1]
         K05129  MUSK; muscle, skeletal, receptor tyrosine kinase [EC:2.7.10.1]
         K08252  E2.7.10.1; receptor protein-tyrosine kinase [EC:2.7.10.1]
         K08897  EPHA10; Eph receptor A10 [EC:2.7.10.1]
         K08898  LMTK2; lemur tyrosine kinase 2 [EC:2.7.10.1]
         K08899  LMTK3; lemur tyrosine kinase 3 [EC:2.7.10.1]
         K12378  TOR; tyrosine-protein kinase receptor torso [EC:2.7.10.1]
         K13415  BRI1; protein brassinosteroid insensitive 1 [EC:2.7.10.1 2.7.11.1]
         K13416  BAK1; brassinosteroid insensitive 1-associated receptor kinase 1 [EC:2.7.10.1 2.7.11.1]
         K13417  SERK4, BKK1; somatic embryogenesis receptor kinase 4 [EC:2.7.10.1 2.7.11.1]
         K13418  SERK1; somatic embryogenesis receptor kinase 1 [EC:2.7.10.1 2.7.11.1]
         K17480  AATK, LMTK1; lemur tyrosine kinase 1 [EC:2.7.10.1]
       2.7.10.2  non-specific protein-tyrosine kinase
         K04447  JAK2; Janus kinase 2 [EC:2.7.10.2]
         K05703  FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
         K05704  SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
         K05705  YES1; tyrosine-protein kinase Yes [EC:2.7.10.2]
         K05725  PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
         K05854  LYN; tyrosine-protein kinase Lyn [EC:2.7.10.2]
         K05855  SYK; spleen tyrosine kinase [EC:2.7.10.2]
         K05856  LCK; lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2]
         K05871  PTK2B, FAK2; focal adhesion kinase 2 [EC:2.7.10.2]
         K06619  ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
         K07360  ZAP70; tyrosine-protein kinase ZAP-70 [EC:2.7.10.2]
         K07363  ITK; IL2-inducible T-cell kinase [EC:2.7.10.2]
         K07364  TEC; tyrosine-protein kinase Tec [EC:2.7.10.2]
         K07370  BTK; Bruton agammaglobulinemia tyrosine kinase [EC:2.7.10.2]
         K07527  FES, FPS; tyrosine-protein kinase Fes/Fps [EC:2.7.10.2]
         K08016  TXK, RLK; tyrosine-protein kinase TXK [EC:2.7.10.2]
         K08253  E2.7.10.2; non-specific protein-tyrosine kinase [EC:2.7.10.2]
         K08885  TNK1; non-receptor tyrosine-protein kinase TNK1 [EC:2.7.10.2]
         K08886  TNK2, ACK1; activated CDC42 kinase 1 [EC:2.7.10.2 2.7.11.1]
         K08887  ABL2; abelson tyrosine-protein kinase 2 [EC:2.7.10.2]
         K08888  MATK; megakaryocyte-associated tyrosine kinase [EC:2.7.10.2]
         K08889  FER, TYK3; tyrosine-protein kinase Fer [EC:2.7.10.2]
         K08890  BLK; B lymphoid tyrosine kinase [EC:2.7.10.2]
         K08891  FGR, SRC2; tyrosine-protein kinase Fgr [EC:2.7.10.2]
         K08892  FRK, PTK5; fyn-related kinase [EC:2.7.10.2]
         K08893  HCK; hemopoietic cell kinase [EC:2.7.10.2]
         K08894  PTK6, BRK; protein tyrosine kinase 6 [EC:2.7.10.2]
         K08895  SRMS; tyrosine-protein kinase Srms [EC:2.7.10.2]
         K08896  BMX, ETK; cytoplasmic tyrosine-protein kinase BMX [EC:2.7.10.2]
         K11217  JAK1; Janus kinase 1 [EC:2.7.10.2]
         K11218  JAK3; Janus kinase 3 [EC:2.7.10.2]
         K11219  TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
         K17510  STYK1; tyrosine-protein kinase STYK1 [EC:2.7.10.2]
         K17511  YRK; proto-oncogene tyrosine-protein kinase YRK [EC:2.7.10.2]
         K17512  SHARK; tyrosine-protein kinase shark [EC:2.7.10.2]
         K17537  SGK223; tyrosine-protein kinase SgK223 [EC:2.7.10.2]
         K17538  PEAK1, SGK269; pseudopodium-enriched atypical kinase 1 [EC:2.7.10.2]
         K17548  PKDCC; extracellular tyrosine-protein kinase PKDCC  [EC:2.7.10.2]
         K23453  src; RSV tyrosine-protein kinase transforming protein Src [EC:2.7.10.2]
       2.7.10.3  bacterial tyrosine kinase
       2.7.10.4  [Src-family] C-terminal protein kinase
     2.7.11  Protein-serine/threonine kinases
       2.7.11.1  non-specific serine/threonine protein kinase
         K00924  TMK; receptor protein kinase TMK [EC:2.7.11.1]
         K02178  BUB1; checkpoint serine/threonine-protein kinase [EC:2.7.11.1]
         K02214  CDC7; cell division control protein 7 [EC:2.7.11.1]
         K02216  CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
         K02218  CSNK1, CKI; casein kinase 1 [EC:2.7.11.1]
         K02861  RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
         K03097  CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
         K03114  SWE1; mitosis inhibitor protein kinase SWE1 [EC:2.7.11.1]
         K03125  TAF1; transcription initiation factor TFIID subunit 1 [EC:2.3.1.48 2.7.11.1]
         K04365  BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
         K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
         K04367  MOS; proto-oncogene serine/threonine-protein kinase mos [EC:2.7.11.1]
         K04372  MKNK, MNK; MAP kinase interacting serine/threonine kinase [EC:2.7.11.1]
         K04373  RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
         K04406  MAP4K3, GLK; mitogen-activated protein kinase kinase kinase kinase 3 [EC:2.7.11.1]
         K04407  MAP4K4, HGK; mitogen-activated protein kinase kinase kinase kinase 4 [EC:2.7.11.1]
         K04408  MAP4K1, HPK1; mitogen-activated protein kinase kinase kinase kinase 1 [EC:2.7.11.1]
         K04409  PAK1; p21-activated kinase 1 [EC:2.7.11.1]
         K04410  PAK2; p21-activated kinase 2 [EC:2.7.11.1]
         K04413  MINK; misshapen/NIK-related kinase [EC:2.7.11.1]
         K04414  MAP4K2, GCK; mitogen-activated protein kinase kinase kinase kinase 2 [EC:2.7.11.1]
         K04429  TAO; thousand and one amino acid protein kinase [EC:2.7.11.1]
         K04442  MAPKAPK5, PRAK; mitogen-activated protein kinase-activated protein kinase 5 [EC:2.7.11.1]
         K04443  MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
         K04444  MAPKAPK3; mitogen-activated protein kinase-activated protein kinase 3 [EC:2.7.11.1]
         K04445  RPS6KA5, MSK1; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
         K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
         K04688  RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
         K04702  PIM1; proto-oncogene serine/threonine-protein kinase Pim-1 [EC:2.7.11.1]
         K04728  ATM, TEL1; serine-protein kinase ATM [EC:2.7.11.1]
         K04730  IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
         K04731  IRAK2; interleukin-1 receptor-associated kinase 2 [EC:2.7.11.1]
         K04732  IRAK3; interleukin-1 receptor-associated kinase 3 [EC:2.7.11.1]
         K04733  IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
         K04757  rsbW; serine/threonine-protein kinase RsbW [EC:2.7.11.1]
         K04981  TRPM6, CHAK2; transient receptor potential cation channel subfamily M member 6 [EC:2.7.11.1]
         K04982  TRPM7, CHAK1; transient receptor potential cation channel subfamily M member 7 [EC:2.7.11.1]
         K05688  PINK1; PTEN induced putative kinase 1 [EC:2.7.11.1]
         K05733  PAK3, MRX30; p21-activated kinase 3 [EC:2.7.11.1]
         K05734  PAK4; p21-activated kinase 4 [EC:2.7.11.1]
         K05735  PAK6; p21-activated kinase 6 [EC:2.7.11.1]
         K05736  PAK5, PAK7; p21-activated kinase 5 [EC:2.7.11.1]
         K05743  LIMK1; LIM domain kinase 1 [EC:2.7.11.1]
         K05744  LIMK2; LIM domain kinase 2 [EC:2.7.11.1]
         K06103  CASK; calcium/calmodulin-dependent serine protein kinase [EC:2.7.11.1]
         K06228  FU; fused [EC:2.7.11.1]
         K06272  ILK; integrin-linked kinase [EC:2.7.11.1]
         K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
         K06379  spoIIAB; stage II sporulation protein AB (anti-sigma F factor) [EC:2.7.11.1]
         K06632  WEE1; wee1-like protein kinase [EC:2.7.11.1]
         K06633  PKMYT; membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase [EC:2.7.11.1]
         K06637  BUB1B, BUBR1, MAD3L; mitotic checkpoint serine/threonine-protein kinase BUB1 beta [EC:2.7.11.1]
         K06640  ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
         K06641  CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
         K06642  PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]
         K06683  CDC15; cell division control protein CDC15 [EC:2.7.11.1]
         K07154  hipA; serine/threonine-protein kinase HipA [EC:2.7.11.1]
         K07178  RIOK1; RIO kinase 1 [EC:2.7.11.1]
         K07179  RIOK2; RIO kinase 2 [EC:2.7.11.1]
         K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
         K07298  STK11, LKB1; serine/threonine-protein kinase 11 [EC:2.7.11.1]
         K08060  CIITA; MHC class II transactivator [EC:2.7.11.1]
         K08269  ULK2, ATG1; serine/threonine-protein kinase ULK2 [EC:2.7.11.1]
         K08282  E2.7.11.1; non-specific serine/threonine protein kinase [EC:2.7.11.1]
         K08333  PIK3R4, VPS15; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]
         K08788  DMPK; dystrophia myotonica-protein kinase [EC:2.7.11.1]
         K08790  STK38, NDR; serine/threonine kinase 38 [EC:2.7.11.1]
         K08791  LATS1_2, Wts; serine/threonine-protein kinase LATS1/2 [EC:2.7.11.1]
         K08793  STK32, YANK; serine/threonine kinase 32 [EC:2.7.11.1]
         K08796  BRSK; BR serine/threonine kinase [EC:2.7.11.1]
         K08797  HUNK; hormonally upregulated Neu-associated kinase [EC:2.7.11.1]
         K08798  MARK; MAP/microtubule affinity-regulating kinase [EC:2.7.11.1]
         K08799  MELK; maternal embryonic leucine zipper kinase [EC:2.7.11.1]
         K08800  NUAK; NUAK family, SNF1-like kinase [EC:2.7.11.1]
         K08801  PASK; PAS domain containing serine/threonine kinase [EC:2.7.11.1]
         K08802  SNRK; SNF related kinase [EC:2.7.11.1]
         K08803  DAPK; death-associated protein kinase [EC:2.7.11.1]
         K08804  STK17; serine/threonine kinase 17 [EC:2.7.11.1]
         K08805  DCLK1_2; doublecortin-like kinase 1/2 [EC:2.7.11.1]
         K08806  PIM2; proto-oncogene serine/threonine-protein kinase Pim-2 [EC:2.7.11.1]
         K08807  PIM3; proto-oncogene serine/threonine-protein kinase Pim-3 [EC:2.7.11.1]
         K08808  PSKH; protein serine kinase H [EC:2.7.11.1]
         K08809  SPEG; striated muscle-specific serine/threonine protein kinase [EC:2.7.11.1]
         K08810  TRIO; triple functional domain protein [EC:2.7.11.1]
         K08811  TSSK, STK22; testis-specific serine kinase [EC:2.7.11.1]
         K08813  STK33; serine/threonine kinase 33 [EC:2.7.11.1]
         K08816  VRK; vaccinia related kinase [EC:2.7.11.1]
         K08826  HIPK; homeodomain interacting protein kinase [EC:2.7.11.1]
         K08827  PRPF4B; serine/threonine-protein kinase PRP4 [EC:2.7.11.1]
         K08831  SRPK2; serine/threonine-protein kinase SRPK2 [EC:2.7.11.1]
         K08832  SRPK3, STK23; serine/threonine-protein kinase SRPK3 [EC:2.7.11.1]
         K08833  MAP4K5, KHS1; mitogen-activated protein kinase kinase kinase kinase 5 [EC:2.7.11.1]
         K08834  MYO3, DFNB30; myosin III [EC:2.7.11.1]
         K08835  OXSR1, STK39; serine/threonine-protein kinase OSR1/STK39 [EC:2.7.11.1]
         K08836  SLK; STE20-like kinase [EC:2.7.11.1]
         K08837  STK10, LOK; serine/threonine kinase 10 [EC:2.7.11.1]
         K08838  STK24_25_MST4; serine/threonine-protein kinase 24/25/MST4 [EC:2.7.11.1]
         K08840  TNIK; TRAF2 and NCK interacting kinase [EC:2.7.11.1]
         K08843  LRRK1; leucine-rich repeat kinase 1 [EC:2.7.11.1]
         K08844  LRRK2; leucine-rich repeat kinase 2 [EC:2.7.11.1]
         K08845  ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
         K08846  RIPK2; receptor-interacting serine/threonine-protein kinase 2 [EC:2.7.11.1]
         K08847  RIPK3; receptor-interacting serine/threonine-protein kinase 3 [EC:2.7.11.1]
         K08848  RIPK4; receptor-interacting serine/threonine-protein kinase 4 [EC:2.7.11.1]
         K08849  MLKL; mixed lineage kinase domain-like [EC:2.7.11.1]
         K08850  AURKX; aurora kinase, other [EC:2.7.11.1]
         K08851  TP53RK, PRPK, BUD32; TP53 regulating kinase and related kinases [EC:2.7.11.1]
         K08852  ERN1; serine/threonine-protein kinase/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-]
         K08853  AAK; AP2-associated kinase [EC:2.7.11.1]
         K08854  BMP2K, BIKE; BMP2 inducible kinase [EC:2.7.11.1]
         K08855  GAK; cyclin G-associated kinase [EC:2.7.11.1]
         K08856  STK16; serine/threonine kinase 16 [EC:2.7.11.1]
         K08857  NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1]
         K08858  SBK; serine/threonine-protein kinase SBK [EC:2.7.11.1]
         K08859  STK35, PDIK1, CLIK1; serine/threonine kinase 35 [EC:2.7.11.1]
         K08860  EIF2AK3, PERK; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
         K08864  TLK; tousled-like kinase [EC:2.7.11.1]
         K08867  WNK, PRKWNK; WNK lysine deficient protein kinase [EC:2.7.11.1]
         K08872  RIOK3, SUDD; RIO kinase 3 [EC:2.7.11.1]
         K08873  SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1]
         K08877  UHMK1, KIS; serine/threonine-protein kinase Kist [EC:2.7.11.1]
         K08878  BCR1, BCR; breakpoint cluster region protein [EC:2.7.11.1]
         K08880  STK19; serine/threonine kinase 19 [EC:2.7.11.1]
         K08884  K08884; serine/threonine protein kinase, bacterial [EC:2.7.11.1]
         K08886  TNK2, ACK1; activated CDC42 kinase 1 [EC:2.7.10.2 2.7.11.1]
         K08957  CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]
         K08958  CSNK1G; casein kinase 1, gamma [EC:2.7.11.1]
         K08959  CSNK1D; casein kinase 1, delta [EC:2.7.11.1]
         K08960  CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]
         K11479  AURKB; aurora kinase B [EC:2.7.11.1]
         K11480  AURKC; aurora kinase C [EC:2.7.11.1]
         K11481  AURKA; aurora kinase A [EC:2.7.11.1]
         K11715  ERN2; serine/threonine-protein kinase/endoribonuclease IRE2 [EC:2.7.11.1 3.1.26.-]
         K11789  DCAF1, VPRBP; DDB1- and CUL4-associated factor 1 [EC:2.7.11.1]
         K11889  impN; type VI secretion system protein ImpN [EC:2.7.11.1]
         K11912  ppkA; serine/threonine-protein kinase PpkA [EC:2.7.11.1]
         K12132  prkC, stkP; eukaryotic-like serine/threonine-protein kinase [EC:2.7.11.1]
         K12567  TTN; titin [EC:2.7.11.1]
         K12761  SNF1; carbon catabolite-derepressing protein kinase [EC:2.7.11.1]
         K12765  IME2; meiosis induction protein kinase IME2/SME1 [EC:2.7.11.1]
         K12766  MDS1, RIM11; serine/threonine-protein kinase MDS1/RIM11 [EC:2.7.11.1]
         K12771  SPS1; sporulation-specific protein 1 [EC:2.7.11.1]
         K12776  MEK1; meiosis-specific serine/threonine-protein kinase MEK1 [EC:2.7.11.1]
         K13302  SGK1; serum/glucocorticoid-regulated kinase 1 [EC:2.7.11.1]
         K13303  SGK2; serum/glucocorticoid-regulated kinase 2 [EC:2.7.11.1]
         K13304  SGK3; serum/glucocorticoid-regulated kinase 3 [EC:2.7.11.1]
         K13412  CPK; calcium-dependent protein kinase [EC:2.7.11.1]
         K13415  BRI1; protein brassinosteroid insensitive 1 [EC:2.7.10.1 2.7.11.1]
         K13416  BAK1; brassinosteroid insensitive 1-associated receptor kinase 1 [EC:2.7.10.1 2.7.11.1]
         K13417  SERK4, BKK1; somatic embryogenesis receptor kinase 4 [EC:2.7.10.1 2.7.11.1]
         K13418  SERK1; somatic embryogenesis receptor kinase 1 [EC:2.7.10.1 2.7.11.1]
         K13419  pknK; serine/threonine-protein kinase PknK [EC:2.7.11.1]
         K13420  FLS2; LRR receptor-like serine/threonine-protein kinase FLS2 [EC:2.7.11.1]
         K13428  EFR; LRR receptor-like serine/threonine-protein kinase EFR [EC:2.7.11.1]
         K13430  PBS1; serine/threonine-protein kinase PBS1 [EC:2.7.11.1]
         K13436  PTI1; pto-interacting protein 1 [EC:2.7.11.1]
         K14498  SNRK2; serine/threonine-protein kinase SRK2 [EC:2.7.11.1]
         K14500  BSK; BR-signaling kinase [EC:2.7.11.1]
         K14502  ASK6_7_9, BIN2; shaggy-related protein kinase (protein brassinosteroid insensitive 2) [EC:2.7.11.1]
         K14510  CTR1; serine/threonine-protein kinase CTR1 [EC:2.7.11.1]
         K14758  HRR25; casein kinase I homolog HRR25 [EC:2.7.11.1]
         K14949  pknG; serine/threonine-protein kinase PknG [EC:2.7.11.1]
         K15048  KALRN; kalirin [EC:2.7.11.1]
         K15409  SRPK1; serine/threonine-protein kinase SRPK1 [EC:2.7.11.1]
         K15904  kae1-bud32; bifunctional N6-L-threonylcarbamoyladenine synthase / protein kinase Bud32 [EC:2.3.1.234 2.7.11.1]
         K16194  EIF2AK1; eukaryotic translation initiation factor 2-alpha kinase 1 [EC:2.7.11.1]
         K16195  EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
         K16196  EIF2AK4, GCN2; eukaryotic translation initiation factor 2-alpha kinase 4 [EC:2.7.11.1]
         K16279  KEG; E3 ubiquitin-protein ligase KEG [EC:2.7.11.1 2.3.2.27]
         K16289  ANKK1; ankyrin repeat and protein kinase domain-containing protein 1 [EC:2.7.11.1]
         K16307  CDC42BP; serine/threonine-protein kinase MRCK [EC:2.7.11.1]
         K16310  NIM1; serine/threonine-protein kinase NIM1 [EC:2.7.11.1]
         K16311  SIK2; serine/threonine-protein kinase SIK2 [EC:2.7.11.1]
         K16312  STK40, SHIK; serine/threonine-protein kinase 40 [EC:2.7.11.1]
         K16313  NRK; Nik-related protein kinase [EC:2.7.11.1]
         K16314  ELM1; serine/threonine-protein kinase ELM1 [EC:2.7.11.1]
         K16315  GSG2; serine/threonine-protein kinase haspin [EC:2.7.11.1]
         K16316  STK31, TDRD8; serine/threonine-protein kinase 31 [EC:2.7.11.1]
         K16510  RPS6KA4, MSK2; ribosomal protein S6 kinase alpha-4 [EC:2.7.11.1]
         K17529  SGK494; uncharacterized serine/threonine-protein kinase SgK494 [EC:2.7.11.1]
         K17530  DCLK3; doublecortin-like kinase 3 [EC:2.7.11.1]
         K17531  OBSCN, ARHGEF30; obscurin-RhoGEF [EC:2.7.11.1]
         K17535  TNNI3K; serine/threonine-protein kinase TNNI3K [EC:2.7.11.1]
         K17539  PDIK1L, CLIK1L; serine/threonine-protein kinase PDIK1L [EC:2.7.11.1]
         K17545  ULK4; serine/threonine-protein kinase ULK4 [EC:2.7.11.1]
         K17752  rsbT; serine/threonine-protein kinase RsbT [EC:2.7.11.1]
         K18529  KSR2; kinase suppressor of Ras 2 [EC:2.7.11.1]
         K18639  KCC4; serine/threonine-protein kinase KCC4 [EC:2.7.11.1]
         K18679  CDR2; mitosis inducer protein kinase Cdr2 [EC:2.7.11.1]
         K18680  CDR1; mitosis inducer protein kinase Cdr1 [EC:2.7.11.1]
         K19008  SIK1; serine/threonine-protein kinase SIK1 [EC:2.7.11.1]
         K19009  SIK3; serine/threonine-protein kinase SIK3 [EC:2.7.11.1]
         K19439  US3; Simplexvirus serine/threonine-protein kinase US3 [EC:2.7.11.1]
         K19440  UL13; Simplexvirus serine/threonine-protein kinase UL13 [EC:2.7.11.1]
         K19455  BGLF4; Lymphocryptovirus serine/threonine-protein kinase BGLF4 [EC:2.7.11.1]
         K19800  SCH9; serine/threonine protein kinase SCH9 [EC:2.7.11.1]
         K19830  YCK3; casein kinase I homolog 3 [EC:2.7.11.1]
         K19833  CLA4; serine/threonine-protein kinase CLA4 [EC:2.7.11.1]
         K19852  KIN1_2; serine/threonine protein kinase KIN1/2 [EC:2.7.11.1]
         K20714  OXI1; serine/threonine-protein kinase OXI1 [EC:2.7.11.1]
         K20715  PHOT; phototropin [EC:2.7.11.1]
         K20718  ER; LRR receptor-like serine/threonine-protein kinase ERECTA [EC:2.7.11.1]
         K20872  NEK2; serine/threonine-protein kinase Nek2 [EC:2.7.11.1]
         K20873  NEK3; serine/threonine-protein kinase Nek3 [EC:2.7.11.1]
         K20877  NEK8; serine/threonine-protein kinase Nek8 [EC:2.7.11.1]
         K20879  NEK10; serine/threonine-protein kinase Nek10 [EC:2.7.11.1]
         K20880  NEK11; serine/threonine-protein kinase Nek11 [EC:2.7.11.1]
         K21157  SAK1; SNF1-activating kinase 1 [EC:2.7.11.1]
         K21158  TOS3; serine/threonine-protein kinase TOS3 [EC:2.7.11.1]
         K21357  ULK1; serine/threonine-protein kinase ULK1 [EC:2.7.11.1]
         K21358  ULK3; serine/threonine-protein kinase ULK3 [EC:2.7.11.1]
         K21506  VPK1; Poxviridae serine/threonine-protein kinase 1 [EC:2.7.11.1]
         K21518  VPK2; Poxviridae serine/threonine-protein kinase 2 [EC:2.7.11.1]
         K21958  FAM20C; extracellular serine/threonine protein kinase FAM20C [EC:2.7.11.1]
         K22008  PSK1; serine/threonine-protein kinase Psk1 [EC:2.7.11.1]
         K22893  pknH; serine/threonine kinase PknH [EC:2.7.11.1]
         K23472  ypkA, yopO; serine/threonine protein kinase YpkA [EC:2.7.11.1]
         K23785  RCK2, CLK1; serine/threonine-protein kinase RCK2 [EC:2.7.11.1]
         K26102  UL97; Cytomegalovirus serine/threonine protein kinase UL97 [EC:2.7.11.1]
         K26447  PK2; Alphabaculovirus probable serine/threonine-protein kinase 2 [EC:2.7.11.1]
         K26450  PK1; Alphabaculovirus/Betabaculovirus serine/threonine-protein kinase 1 [EC:2.7.11.1]
         K26514  ORF36; Rhadinovirus serine/threonine protein kinase [EC:2.7.11.1]
         K27413  ASK1_3_5; shaggy-related protein kinase [EC:2.7.11.1]
         K27414  ASK2_8; shaggy-related protein kinase [EC:2.7.11.1]
         K27589  PSY1R; tyrosine-sulfated glycopeptide receptor 1 [EC:2.7.11.1]
         K27625  PSKR1; phytosulfokine receptor 1 [EC:2.7.11.1 4.6.1.2]
         K27626  PSKR2; phytosulfokine receptor 2 [EC:2.7.11.1]
         K28035  NPR, HAL; NPR/Hal family protein kinase [EC:2.7.11.1]
         K28077  PRK; pollen receptor-like kinase [EC:2.7.11.1]
         K28089  PEPR; leucine-rich repeat receptor-like protein kinase PEPR [EC:2.7.11.1 4.6.1.2]
       2.7.11.2  [pyruvate dehydrogenase (acetyl-transferring)] kinase
       2.7.11.3  dephospho-[reductase kinase] kinase
       2.7.11.4  [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase
       2.7.11.5  [isocitrate dehydrogenase (NADP+)] kinase
       2.7.11.6  [tyrosine 3-monooxygenase] kinase
       2.7.11.7  myosin-heavy-chain kinase
       2.7.11.8  Fas-activated serine/threonine kinase
       2.7.11.9  Goodpasture-antigen-binding protein kinase
       2.7.11.10  IkappaB kinase
       2.7.11.11  cAMP-dependent protein kinase
       2.7.11.12  cGMP-dependent protein kinase
       2.7.11.13  protein kinase C
       2.7.11.14  rhodopsin kinase
       2.7.11.15  beta-adrenergic-receptor kinase
       2.7.11.16  G-protein-coupled receptor kinase
       2.7.11.17  Ca2+/calmodulin-dependent protein kinase
       2.7.11.18  myosin-light-chain kinase
       2.7.11.19  phosphorylase kinase
       2.7.11.20  elongation factor 2 kinase
       2.7.11.21  polo kinase
       2.7.11.22  cyclin-dependent kinase
       2.7.11.23  [RNA-polymerase]-subunit kinase
       2.7.11.24  mitogen-activated protein kinase
       2.7.11.25  mitogen-activated protein kinase kinase kinase
       2.7.11.26  tau-protein kinase
       2.7.11.28  tropomyosin kinase
       2.7.11.29  low-density-lipoprotein receptor kinase
       2.7.11.30  receptor protein serine/threonine kinase
       2.7.11.31  [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase
       2.7.11.32  [pyruvate, phosphate dikinase] kinase
       2.7.11.33  [pyruvate, water dikinase] kinase
       2.7.11.34  NEK6-subfamily protein kinase
       2.7.11.35  CRIK-subfamily protein kinase
       2.7.11.36  MASTL-subfamily protein kinase
       2.7.11.37  MAST-subfamily protein kinase
       2.7.11.38  NEK9 subfamily protein kinase
       2.7.11.39  ROCK-subfamily protein kinase
     2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
     2.7.13  Protein-histidine kinases
     2.7.14  Protein-arginine kinases
     2.7.99  Other protein kinases
   2.8  Transferring sulfur-containing groups
   2.9  Transferring selenium-containing groups
   2.10  Transferring molybdenum- or tungsten-containing groups
 
 3. Hydrolases
   3.1  Acting on ester bonds
     3.1.1  Carboxylic-ester hydrolases
       3.1.1.1  carboxylesterase
       3.1.1.2  arylesterase
       3.1.1.3  triacylglycerol lipase
         K01046  lip, TGL2; triacylglycerol lipase [EC:3.1.1.3]
         K12298  CEL; bile salt-stimulated lipase [EC:3.1.1.3 3.1.1.13]
         K13534  PNPLA3; patatin-like phospholipase domain-containing protein 3 [EC:3.1.1.3 2.3.1.-]
         K13616  AADAC; arylacetamide deacetylase [EC:3.1.1.3]
         K14073  PNLIP, PL; pancreatic triacylglycerol lipase [EC:3.1.1.3]
         K14074  PNLIPRP1, PLRP1; pancreatic lipase-related protein 1 [EC:3.1.1.3]
         K14075  PNLIPRP2, PLRP2; pancreatic lipase-related protein 2 [EC:3.1.1.3]
         K14076  PNLIPRP3, PLRP3; pancreatic lipase-related protein 3 [EC:3.1.1.3]
         K14452  LIPF; gastric triacylglycerol lipase [EC:3.1.1.3]
         K14674  TGL4; TAG lipase / steryl ester hydrolase / phospholipase A2 / LPA acyltransferase [EC:3.1.1.3 3.1.1.13 3.1.1.4 2.3.1.51]
         K14675  TGL3; TAG lipase / lysophosphatidylethanolamine acyltransferase [EC:3.1.1.3 2.3.1.-]
         K16816  PNPLA2, ATGL; patatin-like phospholipase domain-containing protein 2 [EC:3.1.1.3]
         K17900  ATG15, AUT5; lipase ATG15 [EC:3.1.1.3]
         K22283  LIPC; hepatic triacylglycerol lipase [EC:3.1.1.3]
         K22284  LIPG; endothelial lipase [EC:3.1.1.3]
       3.1.1.4  phospholipase A2
       3.1.1.5  lysophospholipase
       3.1.1.6  acetylesterase
       3.1.1.7  acetylcholinesterase
       3.1.1.8  cholinesterase
       3.1.1.10  tropinesterase
       3.1.1.11  pectinesterase
       3.1.1.13  sterol esterase
       3.1.1.14  chlorophyllase
       3.1.1.15  L-arabinonolactonase
       3.1.1.17  gluconolactonase
       3.1.1.19  uronolactonase
       3.1.1.20  tannase
       3.1.1.22  hydroxybutyrate-dimer hydrolase
       3.1.1.23  acylglycerol lipase
       3.1.1.24  3-oxoadipate enol-lactonase
       3.1.1.25  1,4-lactonase
       3.1.1.26  galactolipase
       3.1.1.27  4-pyridoxolactonase
       3.1.1.28  acylcarnitine hydrolase
       3.1.1.29  peptidyl-tRNA hydrolase
       3.1.1.30  D-arabinonolactonase
       3.1.1.31  6-phosphogluconolactonase
       3.1.1.32  phospholipase A1
       3.1.1.33  6-acetylglucose deacetylase
       3.1.1.34  lipoprotein lipase
       3.1.1.35  dihydrocoumarin hydrolase
       3.1.1.36  limonin-D-ring-lactonase
       3.1.1.37  steroid-lactonase
       3.1.1.38  triacetate-lactonase
       3.1.1.39  actinomycin lactonase
       3.1.1.40  orsellinate-depside hydrolase
       3.1.1.41  cephalosporin-C deacetylase
       3.1.1.42  chlorogenate hydrolase
       3.1.1.43  alpha-amino-acid esterase
       3.1.1.44  4-methyloxaloacetate esterase
       3.1.1.45  carboxymethylenebutenolidase
       3.1.1.46  deoxylimonate A-ring-lactonase
       3.1.1.47  1-alkyl-2-acetylglycerophosphocholine esterase
       3.1.1.48  fusarinine-C ornithinesterase
       3.1.1.49  sinapine esterase
       3.1.1.50  wax-ester hydrolase
       3.1.1.51  phorbol-diester hydrolase
       3.1.1.52  phosphatidylinositol deacylase
       3.1.1.53  sialate O-acetylesterase
       3.1.1.54  acetoxybutynylbithiophene deacetylase
       3.1.1.55  acetylsalicylate deacetylase
       3.1.1.56  methylumbelliferyl-acetate deacetylase
       3.1.1.57  2-pyrone-4,6-dicarboxylate lactonase
       3.1.1.58  N-acetylgalactosaminoglycan deacetylase
       3.1.1.59  juvenile-hormone esterase
       3.1.1.60  bis(2-ethylhexyl)phthalate esterase
       3.1.1.61  protein-glutamate methylesterase
       3.1.1.63  11-cis-retinyl-palmitate hydrolase
       3.1.1.64  retinoid isomerohydrolase
       3.1.1.65  L-rhamnono-1,4-lactonase
       3.1.1.66  5-(3,4-diacetoxybut-1-ynyl)-2,2'-bithiophene deacetylase
       3.1.1.67  fatty-acyl-ethyl-ester synthase
       3.1.1.68  xylono-1,4-lactonase
       3.1.1.70  cetraxate benzylesterase
       3.1.1.71  acetylalkylglycerol acetylhydrolase
       3.1.1.72  acetylxylan esterase
       3.1.1.73  feruloyl esterase
       3.1.1.74  cutinase
       3.1.1.75  poly(3-hydroxybutyrate) depolymerase
       3.1.1.76  poly(3-hydroxyoctanoate) depolymerase
       3.1.1.77  acyloxyacyl hydrolase
       3.1.1.78  polyneuridine-aldehyde esterase
       3.1.1.79  hormone-sensitive lipase
       3.1.1.80  acetylajmaline esterase
       3.1.1.81  quorum-quenching N-acyl-homoserine lactonase
       3.1.1.82  pheophorbidase
       3.1.1.83  monoterpene epsilon-lactone hydrolase
       3.1.1.84  cocaine esterase
       3.1.1.85  pimelyl-[acyl-carrier protein] methyl ester esterase
       3.1.1.86  rhamnogalacturonan acetylesterase
       3.1.1.87  fumonisin B1 esterase
       3.1.1.88  pyrethroid hydrolase
       3.1.1.89  protein phosphatase methylesterase-1
       3.1.1.90  all-trans-retinyl ester 13-cis isomerohydrolase
       3.1.1.91  2-oxo-3-(5-oxofuran-2-ylidene)propanoate lactonase
       3.1.1.92  4-sulfomuconolactone hydrolase
       3.1.1.93  mycophenolic acid acyl-glucuronide esterase
       3.1.1.94  versiconal hemiacetal acetate esterase
       3.1.1.95  aclacinomycin methylesterase
       3.1.1.96  D-aminoacyl-tRNA deacylase
       3.1.1.97  methylated diphthine methylhydrolase
       3.1.1.98  [Wnt protein] O-palmitoleoyl-L-serine hydrolase
       3.1.1.99  6-deoxy-6-sulfogluconolactonase
       3.1.1.100  chlorophyllide a hydrolase
       3.1.1.101  poly(ethylene terephthalate) hydrolase
       3.1.1.102  mono(ethylene terephthalate) hydrolase
       3.1.1.103  teichoic acid D-alanine hydrolase
       3.1.1.104  5-phospho-D-xylono-1,4-lactonase
       3.1.1.105  3-O-acetylpapaveroxine carboxylesterase
       3.1.1.106  O-acetyl-ADP-ribose deacetylase
       3.1.1.107  apo-salmochelin esterase
       3.1.1.108  iron(III)-enterobactin esterase
       3.1.1.109  iron(III)-salmochelin esterase
       3.1.1.110  xylono-1,5-lactonase
       3.1.1.111  phosphatidylserine sn-1 acylhydrolase
       3.1.1.112  isoamyl acetate esterase
       3.1.1.113  ethyl acetate hydrolase
       3.1.1.114  methyl acetate hydrolase
       3.1.1.115  D-apionolactonase
       3.1.1.116  sn-1-specific diacylglycerol lipase
       3.1.1.117  (4-O-methyl)-D-glucuronate---lignin esterase
       3.1.1.118  phospholipid sn-1 acylhydrolase
       3.1.1.120  L-fucono-1,5-lactonase
       3.1.1.121  ergosteryl-3beta-O-L-aspartate hydrolase
       3.1.1.122  carbendazim hydrolysing esterase
       3.1.1.123  dehydropreakuammicine esterase
       3.1.1.124  ellagitannin acyl hydrolase
       3.1.1.125  6-deoxy-6-sulfo-D-galactonolactonase
       3.1.1.126  L-galactono-1,5-lactonase
     3.1.2  Thioester hydrolases
     3.1.3  Phosphoric-monoester hydrolases
       3.1.3.1  alkaline phosphatase
       3.1.3.2  acid phosphatase
       3.1.3.3  phosphoserine phosphatase
       3.1.3.4  phosphatidate phosphatase
       3.1.3.5  5'-nucleotidase
       3.1.3.6  3'-nucleotidase
       3.1.3.7  3'(2'),5'-bisphosphate nucleotidase
       3.1.3.8  3-phytase
       3.1.3.9  glucose-6-phosphatase
       3.1.3.10  glucose-1-phosphatase
       3.1.3.11  fructose-bisphosphatase
       3.1.3.12  trehalose-phosphatase
       3.1.3.14  methylphosphothioglycerate phosphatase
       3.1.3.15  histidinol-phosphatase
       3.1.3.16  protein-serine/threonine phosphatase
       3.1.3.17  [phosphorylase] phosphatase
       3.1.3.18  phosphoglycolate phosphatase
       3.1.3.19  glycerol-2-phosphatase
       3.1.3.20  phosphoglycerate phosphatase
       3.1.3.21  glycerol-1-phosphatase
       3.1.3.22  mannitol-1-phosphatase
       3.1.3.23  sugar-phosphatase
       3.1.3.24  sucrose-phosphate phosphatase
       3.1.3.25  inositol-phosphate phosphatase
       3.1.3.26  4-phytase
       3.1.3.27  phosphatidylglycerophosphatase
       3.1.3.28  ADP-phosphoglycerate phosphatase
       3.1.3.29  N-acylneuraminate-9-phosphatase
       3.1.3.32  polynucleotide 3'-phosphatase
       3.1.3.33  polynucleotide 5'-phosphatase
       3.1.3.34  deoxynucleotide 3'-phosphatase
       3.1.3.35  thymidylate 5'-phosphatase
       3.1.3.36  phosphoinositide 5-phosphatase
       3.1.3.37  sedoheptulose-bisphosphatase
       3.1.3.38  3-phosphoglycerate phosphatase
       3.1.3.39  streptomycin-6-phosphatase
       3.1.3.40  guanidinodeoxy-scyllo-inositol-4-phosphatase
       3.1.3.41  4-nitrophenylphosphatase
       3.1.3.42  [glycogen-synthase-D] phosphatase
       3.1.3.43  [pyruvate dehydrogenase (acetyl-transferring)]-phosphatase
       3.1.3.44  [acetyl-CoA carboxylase]-phosphatase
       3.1.3.45  3-deoxy-manno-octulosonate-8-phosphatase
       3.1.3.46  fructose-2,6-bisphosphate 2-phosphatase
       3.1.3.47  [hydroxymethylglutaryl-CoA reductase (NADPH)]-phosphatase
       3.1.3.48  protein-tyrosine-phosphatase
         K01104  E3.1.3.48; protein-tyrosine phosphatase [EC:3.1.3.48]
         K01110  PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
         K02555  MIH1; M-phase inducer tyrosine phosphatase [EC:3.1.3.48]
         K04458  PTPRR; receptor-type tyrosine-protein phosphatase R [EC:3.1.3.48]
         K04459  DUSP2S, MKP; dual specificity protein phosphatase [EC:3.1.3.16 3.1.3.48]
         K05693  PTPRM; receptor-type tyrosine-protein phosphatase mu [EC:3.1.3.48]
         K05694  PTPRB, PTPB; receptor-type tyrosine-protein phosphatase beta [EC:3.1.3.48]
         K05695  PTPRF, LAR; receptor-type tyrosine-protein phosphatase F [EC:3.1.3.48]
         K05696  PTPN1, PTP1B; tyrosine-protein phosphatase non-receptor type 1 [EC:3.1.3.48]
         K05697  PTPN6, SHP1; tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]
         K05698  PTPRJ, DEP1, CD148; receptor-type tyrosine-protein phosphatase eta [EC:3.1.3.48]
         K05766  SSH; protein phosphatase slingshot [EC:3.1.3.16 3.1.3.48]
         K05866  CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
         K05867  CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48]
         K06478  PTPRC, CD45; receptor-type tyrosine-protein phosphatase C [EC:3.1.3.48]
         K06639  CDC14; cell division cycle 14 [EC:3.1.3.16 3.1.3.48]
         K06645  CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48]
         K06776  PTPRK; receptor-type tyrosine-protein phosphatase kappa [EC:3.1.3.48]
         K06777  PTPRD; receptor-type tyrosine-protein phosphatase delta [EC:3.1.3.48]
         K06778  PTPRS; receptor-type tyrosine-protein phosphatase S [EC:3.1.3.48]
         K07293  PTPN11, SHP2; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
         K07817  PTPRN; receptor-type tyrosine-protein phosphatase N [EC:3.1.3.48]
         K08114  PTPRZ; receptor-type tyrosine-protein phosphatase zeta [EC:3.1.3.48]
         K11240  MSG5; tyrosine-protein phosphatase MSG5 [EC:3.1.3.48]
         K13297  PTPRT; receptor-type tyrosine-protein phosphatase T [EC:3.1.3.48]
         K14165  K14165; atypical dual specificity phosphatase [EC:3.1.3.16 3.1.3.48]
         K14167  CDKN3, KAP; cyclin-dependent kinase inhibitor 3 [EC:3.1.3.16 3.1.3.48]
         K14394  ACP1; low molecular weight phosphotyrosine protein phosphatase [EC:3.1.3.2 3.1.3.48]
         K14819  DUSP12, YVH1; dual specificity phosphatase 12 [EC:3.1.3.16 3.1.3.48]
         K15616  EYA1; eyes absent homolog 1 [EC:3.1.3.48]
         K16662  PTPRU; receptor-type tyrosine-protein phosphatase U [EC:3.1.3.48]
         K16667  PTPRG; receptor-type tyrosine-protein phosphatase gamma [EC:3.1.3.48]
         K16910  PTPRQ; receptor-type tyrosine-protein phosphatase Q [EC:3.1.3.48]
         K17614  DUSP3, VHR; dual specificity protein phosphatase 3 [EC:3.1.3.16 3.1.3.48]
         K17619  MDP1; magnesium-dependent phosphatase 1 [EC:3.1.3.48 3.1.3.-]
         K17620  EYA2; eyes absent homolog 2 [EC:3.1.3.48]
         K17621  EYA3; eyes absent homolog 3 [EC:3.1.3.48]
         K17622  EYA4; eyes absent homolog 4 [EC:3.1.3.48]
         K18018  PTPN5; tyrosine-protein phosphatase non-receptor type 5 [EC:3.1.3.48]
         K18019  PTPN7; tyrosine-protein phosphatase non-receptor type 7 [EC:3.1.3.48]
         K18024  PTPN12_18_22; tyrosine-protein phosphatase non-receptor type 12/18/22 [EC:3.1.3.48]
         K18025  PTPN14_21; tyrosine-protein phosphatase non-receptor type 14/21 [EC:3.1.3.48]
         K18026  PTPN2, PTPT; tyrosine-protein phosphatase non-receptor type 2 [EC:3.1.3.48]
         K18027  PTPN3, PTPH1; tyrosine-protein phosphatase non-receptor type 3 [EC:3.1.3.48]
         K18032  PTPRA; receptor-type tyrosine-protein phosphatase A [EC:3.1.3.48]
         K18033  PTPRE; receptor-type tyrosine-protein phosphatase epsilon [EC:3.1.3.48]
         K18034  PTPRH, SAP1; receptor-type tyrosine-protein phosphatase H [EC:3.1.3.48]
         K18035  PTPRO; receptor-type tyrosine-protein phosphatase O [EC:3.1.3.48]
         K18036  PTPRV, ESP; receptor-type tyrosine-protein phosphatase V [EC:3.1.3.48]
         K18037  PTPN4, MEG; tyrosine-protein phosphatase non-receptor type 4 [EC:3.1.3.48]
         K18038  PTPN9, MEG2; tyrosine-protein phosphatase non-receptor type 9 [EC:3.1.3.48]
         K18039  PTPN20; tyrosine-protein phosphatase non-receptor type 20 [EC:3.1.3.48]
         K18040  PTPN23; tyrosine-protein phosphatase non-receptor type 23 [EC:3.1.3.48]
         K18041  PTP4A; protein tyrosine phosphatase type IVA [EC:3.1.3.48]
         K18043  OCA1; tyrosine-protein phosphatase OCA1 [EC:3.1.3.48]
         K18045  SIW14, OCA3; tyrosine-protein phosphatase SIW14 [EC:3.1.3.48]
         K18046  OCA6; tyrosine-protein phosphatase OCA6 [EC:3.1.3.48]
         K18065  CDC25; Cdc25 family phosphatase [EC:3.1.3.48 1.20.4.1]
         K18082  MTMR3_4, ZFYVE10_11; myotubularin-related protein 3/4 [EC:3.1.3.48 3.1.3.64 3.1.3.95]
         K18498  DUSP9, MKP4; dual specificity protein phosphatase 9 [EC:3.1.3.16 3.1.3.48]
         K18993  UBASH3, STS; ubiquitin-associated and SH3 domain-containing protein [EC:3.1.3.48]
         K19269  PGP, PGLP; phosphoglycolate phosphatase [EC:3.1.3.18 3.1.3.48]
         K19806  PTP2_3; tyrosine-protein phosphatase 2/3 [EC:3.1.3.48]
         K19812  SDP1; dual-specificity protein phosphatase SDP1 [EC:3.1.3.48]
         K20216  DUSP10; dual specificity protein phosphatase 10 [EC:3.1.3.16 3.1.3.48]
         K20220  PTP-ER; tyrosine-protein phosphatase ERK [EC:3.1.3.48]
         K20551  MKP2; dual specificity protein phosphatase 1B [EC:3.1.3.16 3.1.3.48]
         K20945  vpsU; tyrosine-protein phosphatase [EC:3.1.3.48]
         K21278  DUSP1; dual specificity protein phosphatase 1 [EC:3.1.3.16 3.1.3.48]
         K21946  DUSP6; dual specificity protein phosphatase 6 [EC:3.1.3.16 3.1.3.48]
         K23474  yopH; tyrosine-protein phosphatase YopH [EC:3.1.3.48]
         K23866  hopD2; effector protein HopD2 [EC:3.1.3.48]
         K25307  wzb, etp; low molecular weight protein-tyrosine phosphatase [EC:3.1.3.48]
         K25994  H1L; Poxviridae dual specificity protein phosphatase H1 [EC:3.1.3.48 3.1.3.-]
         K26451  PTP; Alphabaculovirus tyrosine-protein phosphatase [EC:3.1.3.48]
       3.1.3.49  [pyruvate kinase]-phosphatase
       3.1.3.50  sorbitol-6-phosphatase
       3.1.3.51  dolichyl-phosphatase
       3.1.3.52  [3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)]-phosphatase
       3.1.3.53  [myosin-light-chain] phosphatase
       3.1.3.54  fructose-2,6-bisphosphate 6-phosphatase
       3.1.3.55  caldesmon-phosphatase
       3.1.3.56  inositol-polyphosphate 5-phosphatase
       3.1.3.57  inositol-1,4-bisphosphate 1-phosphatase
       3.1.3.58  sugar-terminal-phosphatase
       3.1.3.59  alkylacetylglycerophosphatase
       3.1.3.60  phosphoenolpyruvate phosphatase
       3.1.3.62  multiple inositol-polyphosphate phosphatase
       3.1.3.63  2-carboxy-D-arabinitol-1-phosphatase
       3.1.3.64  phosphatidylinositol-3-phosphatase
         K01108  MTM1; myotubularin [EC:3.1.3.64 3.1.3.95]
         K18081  MTMR1_2; myotubularin-related protein 1/2 [EC:3.1.3.64 3.1.3.95]
         K18082  MTMR3_4, ZFYVE10_11; myotubularin-related protein 3/4 [EC:3.1.3.48 3.1.3.64 3.1.3.95]
         K18083  MTMR6_7_8; myotubularin-related protein 6/7/8 [EC:3.1.3.64 3.1.3.95]
         K18086  MTMR14; myotubularin-related protein 14 [EC:3.1.3.64 3.1.3.95]
         K21302  sapM; phosphatidylinositol-3-phosphatase [EC:3.1.3.64]
       3.1.3.66  phosphatidylinositol-3,4-bisphosphate 4-phosphatase
       3.1.3.67  phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase
       3.1.3.68  2-deoxyglucose-6-phosphatase
       3.1.3.69  glucosylglycerol 3-phosphatase
       3.1.3.70  mannosyl-3-phosphoglycerate phosphatase
       3.1.3.71  2-phosphosulfolactate phosphatase
       3.1.3.72  5-phytase
       3.1.3.73  adenosylcobalamin/alpha-ribazole phosphatase
       3.1.3.74  pyridoxal phosphatase
       3.1.3.75  phosphoethanolamine/phosphocholine phosphatase
       3.1.3.76  lipid-phosphate phosphatase
       3.1.3.77  acireductone synthase
       3.1.3.78  phosphatidylinositol-4,5-bisphosphate 4-phosphatase
       3.1.3.79  mannosylfructose-phosphate phosphatase
       3.1.3.80  2,3-bisphosphoglycerate 3-phosphatase
       3.1.3.82  D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase
       3.1.3.83  D-glycero-alpha-D-manno-heptose 1,7-bisphosphate 7-phosphatase
       3.1.3.84  ADP-ribose 1''-phosphate phosphatase
       3.1.3.85  glucosyl-3-phosphoglycerate phosphatase
       3.1.3.86  phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase
       3.1.3.87  2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase
       3.1.3.88  5''-phosphoribostamycin phosphatase
       3.1.3.89  5'-deoxynucleotidase
       3.1.3.90  maltose 6'-phosphate phosphatase
       3.1.3.91  7-methylguanosine nucleotidase
       3.1.3.92  kanosamine-6-phosphate phosphatase
       3.1.3.93  L-galactose 1-phosphate phosphatase
       3.1.3.94  D-galactose 1-phosphate phosphatase
       3.1.3.95  phosphatidylinositol-3,5-bisphosphate 3-phosphatase
         K01108  MTM1; myotubularin [EC:3.1.3.64 3.1.3.95]
         K18081  MTMR1_2; myotubularin-related protein 1/2 [EC:3.1.3.64 3.1.3.95]
         K18082  MTMR3_4, ZFYVE10_11; myotubularin-related protein 3/4 [EC:3.1.3.48 3.1.3.64 3.1.3.95]
         K18083  MTMR6_7_8; myotubularin-related protein 6/7/8 [EC:3.1.3.64 3.1.3.95]
         K18086  MTMR14; myotubularin-related protein 14 [EC:3.1.3.64 3.1.3.95]
       3.1.3.96  pseudouridine 5'-phosphatase
       3.1.3.97  3',5'-nucleoside bisphosphate phosphatase
       3.1.3.99  IMP-specific 5'-nucleotidase
       3.1.3.100  thiamine phosphate phosphatase
       3.1.3.101  validoxylamine A 7'-phosphate phosphatase
       3.1.3.102  FMN hydrolase
       3.1.3.103  3-deoxy-D-glycero-D-galacto-nonulopyranosonate 9-phosphatase
       3.1.3.104  5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase
       3.1.3.105  N-acetyl-D-muramate 6-phosphate phosphatase
       3.1.3.106  2-lysophosphatidate phosphatase
       3.1.3.107  amicoumacin phosphatase
       3.1.3.108  nocturnin
       3.1.3.109  ribulose-1,5-bisphosphate 5-phosphatase
       3.1.3.110  4'-phosphopantetheine phosphatase
       3.1.3.111  decaprenylphosphoryl-5-phosphoribose phosphatase
       3.1.3.112  4'-phosphooxetanocin A phosphatase
       3.1.3.113  phospholipid phosphatase
       3.1.3.114  sphingoid-base-1-phosphate phosphatase
       3.1.3.115  ceramide-1-phosphate phosphatase
     3.1.4  Phosphoric-diester hydrolases
     3.1.5  Triphosphoric-monoester hydrolases
     3.1.6  Sulfuric-ester hydrolases
     3.1.7  Diphosphoric-monoester hydrolases
     3.1.8  Phosphoric-triester hydrolases
     3.1.11  Exodeoxyribonucleases producing 5'-phosphomonoesters
     3.1.12  Exodeoxyribonucleases producing 3'-phosphomonoesters
     3.1.13  Exoribonucleases producing 5'-phosphomonoesters
     3.1.14  Exoribonucleases producing 3'-phosphomonoesters
     3.1.15  Exonucleases that are active with either ribo- or deoxyribonucleic acids and produce 5'-phosphomonoesters
     3.1.16  Exonucleases that are active with either ribo- or deoxyribonucleic acids and produce 3'-phosphomonoesters
     3.1.21  Endodeoxyribonucleases producing 5'-phosphomonoesters
     3.1.22  Endodeoxyribonucleases producing 3'-phosphomonoesters
     3.1.25  Site-specific endodeoxyribonucleases that are specific for altered bases
     3.1.26  Endoribonucleases producing 5'-phosphomonoesters
     3.1.27  Endoribonucleases producing 3'-phosphomonoesters
     3.1.30  Endoribonucleases that are active with either ribo- or deoxyribonucleic acids and produce 5'-phosphomonoesters
     3.1.31  Endoribonucleases that are active with either ribo- or deoxyribonucleic acids and produce 3'-phosphomonoesters
   3.2  Glycosylases
   3.3  Acting on ether bonds
   3.4  Acting on peptide bonds (peptidases)
     3.4.11  Aminopeptidases
     3.4.13  Dipeptidases
     3.4.14  Dipeptidyl-peptidases and tripeptidyl-peptidases
     3.4.15  Peptidyl-dipeptidases
     3.4.16  Serine-type carboxypeptidases
     3.4.17  Metallocarboxypeptidases
     3.4.18  Cysteine-type carboxypeptidases
     3.4.19  Omega peptidases
     3.4.21  Serine endopeptidases
       3.4.21.1  chymotrypsin
       3.4.21.2  chymotrypsin C
       3.4.21.3  metridin
       3.4.21.4  trypsin
       3.4.21.5  thrombin
       3.4.21.6  coagulation factor Xa
       3.4.21.7  plasmin
       3.4.21.9  enteropeptidase
       3.4.21.10  acrosin
       3.4.21.12  alpha-lytic endopeptidase
       3.4.21.19  glutamyl endopeptidase
       3.4.21.20  cathepsin G
       3.4.21.21  coagulation factor VIIa
       3.4.21.22  coagulation factor IXa
       3.4.21.25  cucumisin
       3.4.21.26  prolyl oligopeptidase
       3.4.21.27  coagulation factor XIa
       3.4.21.32  brachyurin
       3.4.21.34  plasma kallikrein
       3.4.21.35  tissue kallikrein
       3.4.21.36  pancreatic elastase
       3.4.21.37  leukocyte elastase
       3.4.21.38  coagulation factor XIIa
       3.4.21.39  chymase
       3.4.21.41  complement subcomponent C_overbar_1r_
       3.4.21.42  complement subcomponent C_overbar_1s_
       3.4.21.43  classical-complement-pathway C3/C5 convertase
       3.4.21.45  complement factor I
       3.4.21.46  complement factor D
       3.4.21.47  alternative-complement-pathway C3/C5 convertase
       3.4.21.48  cerevisin
       3.4.21.49  hypodermin C
       3.4.21.50  lysyl endopeptidase
       3.4.21.53  endopeptidase La
       3.4.21.54  gamma-renin
       3.4.21.55  venombin AB
       3.4.21.57  leucyl endopeptidase
       3.4.21.59  tryptase
       3.4.21.60  scutelarin
       3.4.21.61  kexin
       3.4.21.62  subtilisin
       3.4.21.63  oryzin
       3.4.21.64  peptidase K
       3.4.21.65  thermomycolin
       3.4.21.66  thermitase
       3.4.21.67  endopeptidase So
       3.4.21.68  t-plasminogen activator
       3.4.21.69  activated protein C (thrombin-activated peptidase)
       3.4.21.70  pancreatic endopeptidase E
       3.4.21.71  pancreatic elastase II
       3.4.21.72  IgA-specific serine endopeptidase
       3.4.21.73  u-plasminogen activator
       3.4.21.74  venombin A
       3.4.21.75  furin
       3.4.21.76  myeloblastin
       3.4.21.77  semenogelase
       3.4.21.78  granzyme A
       3.4.21.79  granzyme B
       3.4.21.80  streptogrisin A
       3.4.21.81  streptogrisin B
       3.4.21.82  glutamyl endopeptidase II
       3.4.21.83  oligopeptidase B
       3.4.21.84  limulus clotting factor _overbar_C_
       3.4.21.85  limulus clotting factor _overbar_B_
       3.4.21.86  limulus clotting enzyme
       3.4.21.88  repressor LexA
       3.4.21.89  signal peptidase I
       3.4.21.90  togavirin
       3.4.21.91  flavivirin
       3.4.21.92  endopeptidase Clp
       3.4.21.93  proprotein convertase 1
       3.4.21.94  proprotein convertase 2
       3.4.21.95  snake venom factor V activator
       3.4.21.96  lactocepin
       3.4.21.97  assemblin
       3.4.21.98  hepacivirin
       3.4.21.99  spermosin
       3.4.21.100  sedolisin
       3.4.21.101  xanthomonalisin
       3.4.21.102  C-terminal processing peptidase
       3.4.21.103  physarolisin
       3.4.21.104  mannan-binding lectin-associated serine protease-2
       3.4.21.105  rhomboid protease
         K02441  glpG; rhomboid protease GlpG [EC:3.4.21.105]
         K02857  RHBDL1_2_3; rhomboid-related protein 1/2/3 [EC:3.4.21.105]
         K07059  rho2; rhomboid family protease [EC:3.4.21.105]
         K09650  PARL, PSARL, PCP1; rhomboid-like protein [EC:3.4.21.105]
         K09651  RHBDD1, RHBDL4; rhomboid-related protein 4 [EC:3.4.21.105]
         K19225  gluP; rhomboid protease GluP [EC:3.4.21.105]
         K23461  RHO; rhomboid [EC:3.4.21.105]
         K27605  RBL; rhomboid-like protein, plant [EC:3.4.21.105]
         K28366  rho1; rhomboid family protease [EC:3.4.21.105]
       3.4.21.106  hepsin
       3.4.21.107  peptidase Do
       3.4.21.108  HtrA2 peptidase
       3.4.21.109  matriptase
       3.4.21.110  C5a peptidase
       3.4.21.111  aqualysin 1
       3.4.21.112  site-1 protease
       3.4.21.113  pestivirus NS3 polyprotein peptidase
       3.4.21.114  equine arterivirus serine peptidase
       3.4.21.115  infectious pancreatic necrosis birnavirus Vp4 peptidase
       3.4.21.116  SpoIVB peptidase
       3.4.21.117  stratum corneum chymotryptic enzyme
       3.4.21.118  kallikrein 8
       3.4.21.119  kallikrein 13
       3.4.21.120  oviductin
       3.4.21.121  Lys-Lys/Arg-Xaa endopeptidase
       3.4.21.122  transmembrane protease serine 2
       3.4.21.123  kumamolysin
     3.4.22  Cysteine endopeptidases
     3.4.23  Aspartic endopeptidases
     3.4.24  Metalloendopeptidases
     3.4.25  Threonine endopeptidases
     3.4.26  Glutamic endopeptidases
   3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.6  Acting on acid anhydrides
     3.6.1  In phosphorus-containing anhydrides
     3.6.2  In sulfonyl-containing anhydrides
     3.6.4  Acting on acid anhydrides to facilitate cellular and subcellular movement
     3.6.5  Acting on GTP to facilitate cellular and subcellular movement
       3.6.5.1  heterotrimeric G-protein GTPase
       3.6.5.2  small monomeric GTPase
         K07893  RAB6A_C_D; Ras-related protein Rab-6A/C/D [EC:3.6.5.2]
         K07894  RAB6B; Ras-related protein Rab-6B [EC:3.6.5.2]
         K07897  RAB7A, YPT7; Ras-related protein Rab-7A [EC:3.6.5.2]
       3.6.5.3  protein-synthesizing GTPase
       3.6.5.4  signal-recognition-particle GTPase
       3.6.5.5  dynamin GTPase
       3.6.5.6  tubulin GTPase
   3.7  Acting on carbon-carbon bonds
   3.8  Acting on halide bonds
   3.9  Acting on phosphorus-nitrogen bonds
   3.10  Acting on sulfur-nitrogen bonds
   3.11  Acting on carbon-phosphorus bonds
   3.12  Acting on sulfur-sulfur bonds
   3.13  Acting on carbon-sulfur bonds
 
 4. Lyases
 
 5. Isomerases
   5.1  Racemases and epimerases
   5.2  cis-trans-Isomerases
   5.3  Intramolecular oxidoreductases
     5.3.1  Interconverting aldoses and ketoses, and related compounds
       5.3.1.1  triose-phosphate isomerase
         K01803  TPI, tpiA; triosephosphate isomerase (TIM) [EC:5.3.1.1]
       5.3.1.3  D-arabinose isomerase
         K01818  fucI; L-fucose/D-arabinose isomerase [EC:5.3.1.25 5.3.1.3]
       5.3.1.4  L-arabinose isomerase
         K01804  araA; L-arabinose isomerase [EC:5.3.1.4]
       5.3.1.5  xylose isomerase
         K01805  xylA; xylose isomerase [EC:5.3.1.5]
       5.3.1.6  ribose-5-phosphate isomerase
         K01807  rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6]
         K01808  rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6]
       5.3.1.7  mannose isomerase
         K29027  E5.3.1.7; mannose isomerase [EC:5.3.1.7]
       5.3.1.8  mannose-6-phosphate isomerase
         K01809  manA, MPI; mannose-6-phosphate isomerase [EC:5.3.1.8]
         K15916  pgi-pmi; glucose/mannose-6-phosphate isomerase [EC:5.3.1.9 5.3.1.8]
         K16011  algA, xanB, rfbA, wbpW, pslB; mannose-1-phosphate guanylyltransferase / mannose-6-phosphate isomerase [EC:2.7.7.13 5.3.1.8]
         K28465  pmi; mannose-6-phosphate isomerase [EC:5.3.1.8]
       5.3.1.9  glucose-6-phosphate isomerase
         K01810  GPI, pgi; glucose-6-phosphate isomerase [EC:5.3.1.9]
         K06859  pgi1; glucose-6-phosphate isomerase, archaeal [EC:5.3.1.9]
         K13810  tal-pgi; transaldolase / glucose-6-phosphate isomerase [EC:2.2.1.2 5.3.1.9]
         K15916  pgi-pmi; glucose/mannose-6-phosphate isomerase [EC:5.3.1.9 5.3.1.8]
       5.3.1.12  glucuronate isomerase
         K01812  uxaC; glucuronate isomerase [EC:5.3.1.12]
       5.3.1.13  arabinose-5-phosphate isomerase
         K02467  gutQ; arabinose 5-phosphate isomerase [EC:5.3.1.13]
         K06041  kdsD, kpsF; arabinose-5-phosphate isomerase [EC:5.3.1.13]
       5.3.1.14  L-rhamnose isomerase
         K01813  rhaA; L-rhamnose isomerase [EC:5.3.1.14]
         K01820  rhaA; L-rhamnose isomerase / sugar isomerase [EC:5.3.1.14 5.3.1.-]
       5.3.1.15  D-lyxose ketol-isomerase
         K09988  lyxA; D-lyxose ketol-isomerase [EC:5.3.1.15]
       5.3.1.16  1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase
         K01814  hisA; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [EC:5.3.1.16]
         K24017  priA; phosphoribosyl isomerase A [EC:5.3.1.16 5.3.1.24]
       5.3.1.17  5-dehydro-4-deoxy-D-glucuronate isomerase
         K01815  kduI; 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase [EC:5.3.1.17]
       5.3.1.20  ribose isomerase
       5.3.1.21  corticosteroid side-chain-isomerase
       5.3.1.22  hydroxypyruvate isomerase
         K01816  hyi, gip; hydroxypyruvate isomerase [EC:5.3.1.22]
       5.3.1.23  S-methyl-5-thioribose-1-phosphate isomerase
         K08963  mtnA; methylthioribose-1-phosphate isomerase [EC:5.3.1.23]
       5.3.1.24  phosphoribosylanthranilate isomerase
         K01817  trpF; phosphoribosylanthranilate isomerase [EC:5.3.1.24]
         K13498  trpCF; indole-3-glycerol phosphate synthase / phosphoribosylanthranilate isomerase [EC:4.1.1.48 5.3.1.24]
         K13501  TRP1; anthranilate synthase / indole-3-glycerol phosphate synthase / phosphoribosylanthranilate isomerase [EC:4.1.3.27 4.1.1.48 5.3.1.24]
         K24017  priA; phosphoribosyl isomerase A [EC:5.3.1.16 5.3.1.24]
       5.3.1.25  L-fucose isomerase
         K01818  fucI; L-fucose/D-arabinose isomerase [EC:5.3.1.25 5.3.1.3]
       5.3.1.26  galactose-6-phosphate isomerase
         K01819  lacA_B; galactose-6-phosphate isomerase [EC:5.3.1.26]
       5.3.1.27  6-phospho-3-hexuloisomerase
         K08094  hxlB; 6-phospho-3-hexuloisomerase [EC:5.3.1.27]
         K13831  hps-phi; 3-hexulose-6-phosphate synthase / 6-phospho-3-hexuloisomerase [EC:4.1.2.43 5.3.1.27]
       5.3.1.28  D-sedoheptulose-7-phosphate isomerase
         K03271  gmhA, lpcA; D-sedoheptulose 7-phosphate isomerase [EC:5.3.1.28]
       5.3.1.29  ribose-1,5-bisphosphate isomerase
         K18237  K18237; ribose 1,5-bisphosphate isomerase [EC:5.3.1.29]
       5.3.1.30  5-deoxy-glucuronate isomerase
         K03337  iolB; 5-deoxy-glucuronate isomerase [EC:5.3.1.30]
       5.3.1.31  sulfoquinovose isomerase
         K18479  yihS; sulfoquinovose isomerase [EC:5.3.1.31]
         K28652  sqvD; sulfoquinovose isomerase [EC:5.3.1.31]
       5.3.1.32  (4S)-4-hydroxy-5-phosphooxypentane-2,3-dione isomerase
         K11530  lsrG; (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase [EC:5.3.1.32]
       5.3.1.33  L-erythrulose-1-phosphate isomerase
         K21910  eryH, lerI; L-erythrulose 1-phosphate isomerase [EC:5.3.1.33]
       5.3.1.34  D-erythrulose 4-phosphate isomerase
         K21911  eryI; D-erythrulose 4-phosphate isomerase [EC:5.3.1.34]
       5.3.1.35  2-dehydrotetronate isomerase
         K22131  otnI; 2-dehydrotetronate isomerase [EC:5.3.1.35]
       5.3.1.36  D-apiose isomerase
         K24672  apsI; D-apiose isomerase [EC:5.3.1.36]
       5.3.1.37  4-deoxy-4-sulfo-D-erythrose isomerase
         K28646  sqwI; 4-deoxy-4-sulfo-D-erythrose isomerase [EC:5.3.1.37]
     5.3.2  Interconverting keto- and enol-groups
     5.3.3  Transposing C=C bonds
     5.3.4  Transposing S-S bonds
     5.3.99  Other intramolecular oxidoreductases
   5.4  Intramolecular transferases
   5.5  Intramolecular lyases
   5.6  Isomerases altering macromolecular conformation
   5.99  Other isomerases
 
 6. Ligases
   6.1  Forming carbon-oxygen bonds
     6.1.1  Ligases forming aminoacyl-tRNA and related compounds
       6.1.1.1  tyrosine---tRNA ligase
         K01866  YARS, tyrS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
       6.1.1.2  tryptophan---tRNA ligase
         K01867  WARS, trpS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
       6.1.1.3  threonine---tRNA ligase
         K01868  TARS, thrS; threonyl-tRNA synthetase [EC:6.1.1.3]
       6.1.1.4  leucine---tRNA ligase
         K01869  LARS, leuS; leucyl-tRNA synthetase [EC:6.1.1.4]
       6.1.1.5  isoleucine---tRNA ligase
         K01870  IARS, ileS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
       6.1.1.6  lysine---tRNA ligase
         K04566  lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6]
         K04567  KARS, lysS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
       6.1.1.7  alanine---tRNA ligase
         K01872  AARS, alaS; alanyl-tRNA synthetase [EC:6.1.1.7]
       6.1.1.9  valine---tRNA ligase
         K01873  VARS, valS; valyl-tRNA synthetase [EC:6.1.1.9]
       6.1.1.10  methionine---tRNA ligase
         K01874  MARS, metG; methionyl-tRNA synthetase [EC:6.1.1.10]
       6.1.1.11  serine---tRNA ligase
         K01875  SARS, serS; seryl-tRNA synthetase [EC:6.1.1.11]
       6.1.1.12  aspartate---tRNA ligase
         K01876  DARS2, aspS; aspartyl-tRNA synthetase [EC:6.1.1.12]
         K22503  DARS1; aspartyl-tRNA synthetase [EC:6.1.1.12]
         K24278  ERDS; ergosteryl-3beta-O-L-aspartate synthase [EC:6.1.1.12 2.3.2.37]
       6.1.1.13  D-alanine---poly(phosphoribitol) ligase
         K03367  dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 [EC:6.1.1.13]
         K14188  dltC; D-alanine--poly(phosphoribitol) ligase subunit 2 [EC:6.1.1.13]
       6.1.1.14  glycine---tRNA ligase
         K01878  glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]
         K01879  glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]
         K01880  GARS, glyS1; glycyl-tRNA synthetase [EC:6.1.1.14]
         K14164  glyQS; glycyl-tRNA synthetase [EC:6.1.1.14]
       6.1.1.15  proline---tRNA ligase
         K01881  PARS, proS; prolyl-tRNA synthetase [EC:6.1.1.15]
         K14163  EPRS; bifunctional glutamyl/prolyl-tRNA synthetase [EC:6.1.1.17 6.1.1.15]
       6.1.1.16  cysteine---tRNA ligase
         K01883  CARS, cysS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
         K01884  cysS1; cysteinyl-tRNA synthetase, unknown class [EC:6.1.1.16]
       6.1.1.17  glutamate---tRNA ligase
         K01885  EARS, gltX; glutamyl-tRNA synthetase [EC:6.1.1.17]
         K14163  EPRS; bifunctional glutamyl/prolyl-tRNA synthetase [EC:6.1.1.17 6.1.1.15]
       6.1.1.18  glutamine---tRNA ligase
         K01886  QARS, glnS; glutaminyl-tRNA synthetase [EC:6.1.1.18]
       6.1.1.19  arginine---tRNA ligase
         K01887  RARS, argS; arginyl-tRNA synthetase [EC:6.1.1.19]
       6.1.1.20  phenylalanine---tRNA ligase
         K01889  FARSA, pheS; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
         K01890  FARSB, pheT; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
       6.1.1.21  histidine---tRNA ligase
         K01892  HARS, hisS; histidyl-tRNA synthetase [EC:6.1.1.21]
       6.1.1.22  asparagine---tRNA ligase
         K01893  NARS, asnS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
       6.1.1.23  aspartate---tRNAAsn ligase
         K09759  aspC, aspS; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23]
       6.1.1.24  glutamate---tRNAGln ligase
         K09698  gltX; nondiscriminating glutamyl-tRNA synthetase [EC:6.1.1.24]
       6.1.1.26  pyrrolysine---tRNAPyl ligase
         K11627  pylS; pyrrolysyl-tRNA synthetase [EC:6.1.1.26]
       6.1.1.27  O-phospho-L-serine---tRNA ligase
         K07587  sepRS; O-phosphoseryl-tRNA synthetase [EC:6.1.1.27]
     6.1.2  acid-alcohol ligases (ester synthases)
     6.1.3  Cyclo-ligases
   6.2  Forming carbon-sulfur bonds
   6.3  Forming carbon-nitrogen bonds
   6.4  Forming carbon-carbon bonds
   6.5  Forming phosphoric-ester bonds
   6.6  Forming nitrogen-metal bonds
   6.7  Forming nitrogen-nitrogen bonds
 
 7. Translocases

[ BRITE | KEGG2 | KEGG ]
Last updated: July 29, 2026
EC number data are obtained from ExplorEnz