KEGG   PATHWAY: ngi05200
Entry
ngi05200                    Pathway                                
Name
Pathways in cancer - Nannospalax galili (Upper Galilee mountains blind mole rat)
Class
Human Diseases; Cancer: overview
Pathway map
ngi05200  Pathways in cancer
ngi05200

Organism
Nannospalax galili (Upper Galilee mountains blind mole rat) [GN:ngi]
Gene
103725530  Dcc; DCC netrin 1 receptor [KO:K06765]
103744668  caspase-3-like [KO:K02187] [EC:3.4.22.56]
103750475  Casp3; caspase 3 [KO:K02187] [EC:3.4.22.56]
103725336  Casp9; caspase 9 [KO:K04399] [EC:3.4.22.62]
103747007  Appl1; adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 [KO:K08733]
103734864  Cdh1; cadherin 1 [KO:K05689]
103747127  Ctnnb1; catenin beta 1 [KO:K02105]
103735958  Ctnna3; catenin alpha 3 [KO:K05691]
103735149  Ctnna1; catenin alpha 1 [KO:K05691]
103749435  Ctnna2; catenin alpha 2 [KO:K05691]
103748223  Axin1; axin 1 [KO:K02157]
103742203  Axin2; axin 2 [KO:K04385]
103737324  Apc2; APC2, WNT signaling pathway regulator [KO:K02085]
103735168  Apc; APC, WNT signaling pathway regulator [KO:K02085]
103741948  Gsk3b; glycogen synthase kinase 3 beta [KO:K03083] [EC:2.7.11.26]
103729786  Tcf7; transcription factor 7 (T-cell specific, HMG-box) [KO:K02620]
103739783  Tcf7l1; transcription factor 7 like 1 [KO:K04490]
103731749  Tcf7l2; transcription factor 7 like 2 [KO:K04491]
103742515  Lef1; lymphoid enhancer binding factor 1 [KO:K04492]
103747285  Birc5; baculoviral IAP repeat containing 5 [KO:K08731]
103743920  Myc; v-myc avian myelocytomatosis viral oncogene homolog [KO:K04377]
103751498  Ccnd1; cyclin D1 [KO:K04503]
103750567  Wnt1; Wnt family member 1 [KO:K03209]
103734912  Wnt2b; Wnt family member 2B [KO:K00182]
103737375  Wnt2; Wnt family member 2 [KO:K00182]
103739037  Wnt3a; Wnt family member 3A [KO:K00312]
103724772  Wnt3; Wnt family member 3 [KO:K00312]
103746395  Wnt4; Wnt family member 4 [KO:K00408]
103739374  Wnt5b; Wnt family member 5B [KO:K00444]
103749032  Wnt5a; Wnt family member 5A [KO:K00444]
103727729  Wnt6; Wnt family member 6 [KO:K00445]
103743417  Wnt7b; Wnt family member 7B [KO:K00572]
103730373  Wnt7a; Wnt family member 7A [KO:K00572]
103735176  Wnt8a; Wnt family member 8A [KO:K00714]
103743982  Wnt8b; Wnt family member 8B [KO:K00714]
103740409  Wnt9a; Wnt family member 9A [KO:K01064]
103724773  Wnt9b; Wnt family member 9B [KO:K01064]
103750565  Wnt10b; Wnt family member 10B [KO:K01357]
103727730  Wnt10a; Wnt family member 10A [KO:K01357]
103743015  Wnt11; Wnt family member 11 [KO:K01384]
103730604  Wnt16; Wnt family member 16 [KO:K01558]
103736031  Fzd7; frizzled class receptor 7 [KO:K02432]
103725249  Fzd1; frizzled class receptor 1 [KO:K02432]
103738297  Fzd2; frizzled class receptor 2 [KO:K02235]
103729990  Fzd3; frizzled class receptor 3 [KO:K02329]
103742963  Fzd4; frizzled class receptor 4 [KO:K02354]
103744444  Fzd5; frizzled class receptor 5 [KO:K02375]
103748031  Fzd8; frizzled class receptor 8 [KO:K02375]
103748769  Fzd6; frizzled class receptor 6 [KO:K02376]
103746251  Fzd9; frizzled class receptor 9 [KO:K02842]
103750619  Fzd10; frizzled class receptor 10 [KO:K02842]
103744519  Lrp5; LDL receptor related protein 5 [KO:K03068]
103737771  Lrp6; LDL receptor related protein 6 [KO:K03068]
103732646  Dvl3; dishevelled segment polarity protein 3 [KO:K02353]
103749746  Dvl1; dishevelled segment polarity protein 1 [KO:K02353]
103752158  Dvl2; dishevelled segment polarity protein 2 [KO:K02353]
103733205  Frat1; FRAT1, WNT signaling pathway regulator [KO:K03069]
103733235  Frat2; FRAT2, WNT signaling pathway regulator [KO:K03096]
103742495  F2; coagulation factor II, thrombin [KO:K01313] [EC:3.4.21.5]
103744123  Agt; angiotensinogen [KO:K09821]
103752270  F2r; coagulation factor II thrombin receptor [KO:K03914]
103726912  F2rl3; F2R like thrombin/trypsin receptor 3 [KO:K04236]
103732526  Lpar1; lysophosphatidic acid receptor 1 [KO:K04289]
103726831  Lpar2; lysophosphatidic acid receptor 2 [KO:K04291]
103728104  Lpar3; lysophosphatidic acid receptor 3 [KO:K04294]
103737817  Lpar4; lysophosphatidic acid receptor 4 [KO:K04275]
103727518  Lpar5; lysophosphatidic acid receptor 5 [KO:K08390]
103726741  Lpar6; lysophosphatidic acid receptor 6 [KO:K04273]
103737006  type-1 angiotensin II receptor [KO:K04166]
103745994  Agtr1; angiotensin II receptor type 1 [KO:K04166]
103748670  Gna12; G protein subunit alpha 12 [KO:K04346]
103742208  Gna13; G protein subunit alpha 13 [KO:K04639]
103727935  Arhgef12; Rho guanine nucleotide exchange factor 12 [KO:K07532]
103750204  Arhgef11; Rho guanine nucleotide exchange factor 11 [KO:K12331]
103744614  Arhgef1; Rho guanine nucleotide exchange factor 1 [KO:K12330]
103725130  Plekhg5; pleckstrin homology and RhoGEF domain containing G5 [KO:K19464]
103743359  transforming protein RhoA-like [KO:K04513]
103750189  Rhoa; ras homolog family member A [KO:K04513]
103728977  Rock1; Rho associated coiled-coil containing protein kinase 1 [KO:K04514] [EC:2.7.11.1]
103747607  Rock2; Rho associated coiled-coil containing protein kinase 2 [KO:K17388] [EC:2.7.11.1]
103745020  Cxcl12; C-X-C motif chemokine ligand 12 [KO:K10031]
103734615  Cxcr4; C-X-C motif chemokine receptor 4 [KO:K04189]
103747835  Gnai3; G protein subunit alpha i3 [KO:K04630]
103750163  Gnai2; G protein subunit alpha i2 [KO:K04630]
103724646  guanine nucleotide-binding protein G(i) subunit alpha-2-like [KO:K04630]
103732220  Gnai1; G protein subunit alpha i1 [KO:K04630]
103751846  Ptger1; prostaglandin E receptor 1 [KO:K04258]
103739242  Ptger2; prostaglandin E receptor 2 [KO:K04259]
103744346  Ptger3; prostaglandin E receptor 3 [KO:K04260]
103741335  Ptger4; prostaglandin E receptor 4 [KO:K04261]
103741475  Gnas; GNAS complex locus [KO:K04632]
103741466  neuroendocrine secretory protein 55 [KO:K04632]
103741433  Adcy1; adenylate cyclase 1 [KO:K08041] [EC:4.6.1.1]
103735350  Adcy2; adenylate cyclase 2 [KO:K08042] [EC:4.6.1.1]
103746460  Adcy3; adenylate cyclase 3 [KO:K08043] [EC:4.6.1.1]
103739411  Adcy4; adenylate cyclase 4 [KO:K08044] [EC:4.6.1.1]
103741989  Adcy5; adenylate cyclase 5 [KO:K08045] [EC:4.6.1.1]
103750558  Adcy6; adenylate cyclase 6 [KO:K08046] [EC:4.6.1.1]
103730120  Adcy7; adenylate cyclase 7 [KO:K08047] [EC:4.6.1.1]
103743923  Adcy8; adenylate cyclase 8 [KO:K08048] [EC:4.6.1.1]
103744458  Adcy9; adenylate cyclase 9 [KO:K08049] [EC:4.6.1.1]
103751850  Prkaca; protein kinase cAMP-activated catalytic subunit alpha [KO:K04345] [EC:2.7.11.11]
103728095  Prkacb; protein kinase cAMP-activated catalytic subunit beta [KO:K04345] [EC:2.7.11.11]
103749764  Gnb1; G protein subunit beta 1 [KO:K04536]
103733509  Gnb2; G protein subunit beta 2 [KO:K04537]
103727502  Gnb3; G protein subunit beta 3 [KO:K07825]
103738592  Gnb4; G protein subunit beta 4 [KO:K04538]
103731407  Gnb5; G protein subunit beta 5 [KO:K04539]
103739246  Gng2; G protein subunit gamma 2 [KO:K07826]
103737671  Gng3; G protein subunit gamma 3 [KO:K04540]
103745125  Gng4; G protein subunit gamma 4 [KO:K04541]
103728101  Gng5; G protein subunit gamma 5 [KO:K04542]
103737284  Gng7; G protein subunit gamma 7 [KO:K04543]
103724710  Gng8; G protein subunit gamma 8 [KO:K04544]
108490535  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10-like [KO:K04545]
103732533  Gng10; G protein subunit gamma 10 [KO:K04545]
103725218  Gng11; G protein subunit gamma 11 [KO:K04546]
103743355  Gng12; G protein subunit gamma 12 [KO:K04347]
103751889  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 [KO:K04347]
103752404  Gng13; G protein subunit gamma 13 [KO:K04547]
103725217  Gngt1; G protein subunit gamma transducin 1 [KO:K04548]
103738360  Gngt2; G protein subunit gamma transducin 2 [KO:K04549]
103751683  Col4a2; collagen type IV alpha 2 chain [KO:K06237]
103751684  Col4a1; collagen type IV alpha 1 chain [KO:K06237]
103750063  Col4a5; collagen type IV alpha 5 chain [KO:K06237]
103750029  Col4a6; collagen type IV alpha 6 chain [KO:K06237]
103727826  Col4a4; collagen type IV alpha 4 chain [KO:K06237]
103727827  Col4a3; collagen type IV alpha 3 chain [KO:K06237]
103735414  Lama1; laminin subunit alpha 1 [KO:K05637]
103740954  laminin subunit alpha-1-like [KO:K05637]
103729744  Lama2; laminin subunit alpha 2 [KO:K05637]
103742237  Lama5; laminin subunit alpha 5 [KO:K06240]
103745694  Lama3; laminin subunit alpha 3 [KO:K06240]
103749527  Lama4; laminin subunit alpha 4 [KO:K06241]
103732168  Lamb1; laminin subunit beta 1 [KO:K05636]
103750198  Lamb2; laminin subunit beta 2 [KO:K06243]
103727074  Lamb3; laminin subunit beta 3 [KO:K06244]
103732167  Lamb4; laminin subunit beta 4 [KO:K06245]
103726706  Lamc1; laminin subunit gamma 1 [KO:K05635]
103726677  Lamc2; laminin subunit gamma 2 [KO:K06246]
103727706  Lamc3; laminin subunit gamma 3 [KO:K06247]
103727691  Fn1; fibronectin 1 [KO:K05717]
103734059  Itga2; integrin subunit alpha 2 [KO:K06481]
103738294  Itga2b; integrin subunit alpha 2b [KO:K06476]
103738376  Itga3; integrin subunit alpha 3 [KO:K06482]
103751741  Itga6; integrin subunit alpha 6 [KO:K06485]
103728788  Itgav; integrin subunit alpha V [KO:K06487]
103745645  Itgb1; integrin subunit beta 1 [KO:K05719]
103748419  Ptk2; protein tyrosine kinase 2 [KO:K05725] [EC:2.7.10.2]
103738596  Pik3ca; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha [KO:K00922] [EC:2.7.1.153]
103733121  Pik3cd; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta [KO:K00922] [EC:2.7.1.153]
103742946  Pik3cb; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta [KO:K00922] [EC:2.7.1.153]
103738715  Pik3r1; phosphoinositide-3-kinase regulatory subunit 1 [KO:K02649]
103726879  Pik3r2; phosphoinositide-3-kinase regulatory subunit 2 [KO:K02649]
103730305  Pik3r3; phosphoinositide-3-kinase regulatory subunit 3 [KO:K02649]
103738044  Pten; phosphatase and tensin homolog [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
103748169  Nkx3-1; NK3 homeobox 1 [KO:K09348]
103746884  Akt3; AKT serine/threonine kinase 3 [KO:K04456] [EC:2.7.11.1]
103750757  Akt2; AKT serine/threonine kinase 2 [KO:K04456] [EC:2.7.11.1]
103752536  Akt1; AKT serine/threonine kinase 1 [KO:K04456] [EC:2.7.11.1]
103743976  Chuk; conserved helix-loop-helix ubiquitous kinase [KO:K04467] [EC:2.7.11.10]
103726621  Ikbkb; inhibitor of nuclear factor kappa B kinase subunit beta [KO:K07209] [EC:2.7.11.10]
103731232  Ikbkg; inhibitor of nuclear factor kappa B kinase subunit gamma [KO:K07210]
103734016  Nfkbia; NFKB inhibitor alpha [KO:K04734]
103728077  Nfkb1; nuclear factor kappa B subunit 1 [KO:K02580]
103744019  Nfkb2; nuclear factor kappa B subunit 2 [KO:K04469]
103724994  Rela; RELA proto-oncogene, NF-kB subunit [KO:K04735]
103726651  Ptgs2; prostaglandin-endoperoxide synthase 2 [KO:K11987] [EC:1.14.99.1]
103724501  Nos2; nitric oxide synthase 2 [KO:K13241] [EC:1.14.13.39]
103740099  Bcl2; BCL2, apoptosis regulator [KO:K02161]
103731538  Birc2; baculoviral IAP repeat-containing protein 2 [KO:K16060]
103746493  Birc3; baculoviral IAP repeat containing 3 [KO:K16060]
103734850  Xiap; X-linked inhibitor of apoptosis [KO:K04725] [EC:2.3.2.27]
103742298  Birc7; baculoviral IAP repeat containing 7 [KO:K16061]
103731080  Bcl2l1; BCL2 like 1 [KO:K04570]
103734496  Traf1; TNF receptor associated factor 1 [KO:K03172]
103741188  Traf2; TNF receptor associated factor 2 [KO:K03173] [EC:2.3.2.27]
103727622  Traf3; TNF receptor associated factor 3 [KO:K03174]
103730465  Traf4; TNF receptor associated factor 4 [KO:K09848]
103727039  Traf5; TNF receptor associated factor 5 [KO:K09849]
103749513  Traf6; TNF receptor associated factor 6 [KO:K03175] [EC:2.3.2.27]
103732897  Mtor; mechanistic target of rapamycin [KO:K07203] [EC:2.7.11.1]
103741760  Rps6kb1; ribosomal protein S6 kinase B1 [KO:K04688] [EC:2.7.11.1]
103725586  Rps6kb2; ribosomal protein S6 kinase B2 [KO:K04688] [EC:2.7.11.1]
103738795  Bad; BCL2 associated agonist of cell death [KO:K02158]
103747066  Foxo1; forkhead box O1 [KO:K07201]
103745079  Mdm2; MDM2 proto-oncogene [KO:K06643] [EC:2.3.2.27]
103752115  Tp53; tumor protein p53 [KO:K04451]
103737662  Cdkn1b; cyclin dependent kinase inhibitor 1B [KO:K06624]
103739652  Cdkn1a; cyclin dependent kinase inhibitor 1A [KO:K06625]
103734698  Bcr; BCR, RhoGEF and GTPase activating protein [KO:K08878] [EC:2.7.11.1]
103736271  breakpoint cluster region protein [KO:K08878] [EC:2.7.11.1]
103727721  Abl1; ABL proto-oncogene 1, non-receptor tyrosine kinase [KO:K06619] [EC:2.7.10.2]
103741458  Crkl; CRK like proto-oncogene, adaptor protein [KO:K04438]
103730505  Crk; CRK proto-oncogene, adaptor protein [KO:K04438]
103727895  Cbl; Cbl proto-oncogene [KO:K04707] [EC:2.3.2.27]
103735895  Stat5a; signal transducer and activator of transcription 5A [KO:K11223]
103735893  Stat5b; signal transducer and activator of transcription 5B [KO:K11224]
103739645  Pim1; Pim-1 proto-oncogene, serine/threonine kinase [KO:K04702] [EC:2.7.11.1]
103741656  Pim2; Pim-2 proto-oncogene, serine/threonine kinase [KO:K08806] [EC:2.7.11.1]
103726185  Kng1; kininogen 1 [KO:K03898]
103732886  Edn1; endothelin 1 [KO:K16366]
103727686  Bdkrb1; bradykinin receptor B1 [KO:K03915]
103727666  Bdkrb2; bradykinin receptor B2 [KO:K03916]
103729397  Ednra; endothelin receptor type A [KO:K04197]
103746815  Ednrb; endothelin receptor type B [KO:K04198]
103734421  Gnaq; guanine nucleotide-binding protein G(q) subunit alpha [KO:K04634]
103737243  Gna11; G protein subunit alpha 11 [KO:K04635]
103735195  Plcb1; phospholipase C beta 1 [KO:K05858] [EC:3.1.4.11]
103738797  Plcb3; phospholipase C beta 3 [KO:K05858] [EC:3.1.4.11]
103741502  Plcb2; phospholipase C beta 2 [KO:K05858] [EC:3.1.4.11]
103742202  Prkca; protein kinase C alpha [KO:K02677] [EC:2.7.11.13]
103746928  Prkcb; protein kinase C beta [KO:K19662] [EC:2.7.11.13]
103729666  Prkcg; protein kinase C gamma [KO:K19663] [EC:2.7.11.13]
103746951  Il2; interleukin 2 [KO:K05429]
103747047  Il4; interleukin 4 [KO:K05430]
103747045  Il5; interleukin 5 [KO:K05428]
103740849  Il6; interleukin 6 [KO:K05405]
103727963  Il7; interleukin 7 [KO:K05431]
103745345  Il12a; interleukin 12A [KO:K05406]
103724546  Il12b; interleukin 12B [KO:K05425]
103747046  Il13; interleukin 13 [KO:K05435]
103742384  Il15; interleukin 15 [KO:K05433]
103746524  Il23a; interleukin 23 subunit alpha [KO:K05426]
103733506  Epo; erythropoietin [KO:K05437]
103736148  interferon alpha-12-like [KO:K05414]
103746654  interferon alpha-1-like [KO:K05414]
103746653  interferon alpha-12-like [KO:K05414]
103731654  interferon alpha-13-like [KO:K05414]
103732546  interferon alpha-13-like [KO:K05414]
103745085  Ifng; interferon gamma [KO:K04687]
103727306  Il2ra; interleukin 2 receptor subunit alpha [KO:K05068]
103748643  Il2rb; interleukin 2 receptor subunit beta [KO:K05069]
103751955  Il2rg; interleukin 2 receptor subunit gamma [KO:K05070]
103750125  Il3ra; interleukin 3 receptor subunit alpha [KO:K04737]
103741011  Il4r; interleukin 4 receptor [KO:K05071]
103748646  cytokine receptor common subunit beta-like [KO:K04738]
103748645  interleukin-3 receptor class 2 subunit beta-like [KO:K04738]
103751211  Il5ra; interleukin 5 receptor subunit alpha [KO:K05067]
103751364  Il6r; interleukin 6 receptor [KO:K05055]
103739911  Il6st; interleukin 6 signal transducer [KO:K05060]
103741311  Il7r; interleukin 7 receptor [KO:K05072]
103726945  Il12rb1; interleukin 12 receptor subunit beta 1 [KO:K05063]
103743352  Il12rb2; interleukin 12 receptor subunit beta 2 [KO:K05064]
103743079  Il13ra1; interleukin 13 receptor subunit alpha 1 [KO:K05076]
103727307  Il15ra; interleukin 15 receptor subunit alpha [KO:K05074]
108490034  interleukin-15 receptor subunit alpha-like [KO:K05074]
103743351  Il23r; interleukin 23 receptor [KO:K05065]
103734578  Epor; erythropoietin receptor [KO:K05079]
103736454  interferon alpha/beta receptor 1-like [KO:K05130]
103736458  Ifnar2; interferon alpha and beta receptor subunit 2 [KO:K05131]
103724895  Ifngr1; interferon gamma receptor 1 [KO:K05132]
103736453  Ifngr2; interferon gamma receptor 2 [KO:K05133]
103736385  Eml4; echinoderm microtubule associated protein like 4 [KO:K15420]
103744649  Alk; anaplastic lymphoma receptor tyrosine kinase [KO:K05119] [EC:2.7.10.1]
103727451  Rasgrp1; RAS guanyl releasing protein 1 [KO:K04350]
103738782  Rasgrp2; RAS guanyl releasing protein 2 [KO:K12361]
103746759  Rasgrp3; RAS guanyl releasing protein 3 [KO:K12362]
103750713  Rasgrp4; RAS guanyl releasing protein 4 [KO:K12363]
103732475  Jak1; Janus kinase 1 [KO:K11217] [EC:2.7.10.2]
103740979  Jak2; Janus kinase 2 [KO:K04447] [EC:2.7.10.2]
103726892  Jak3; Janus kinase 3 [KO:K11218] [EC:2.7.10.2]
103735896  Stat3; signal transducer and activator of transcription 3 [KO:K04692]
103736156  Stat1; signal transducer and activator of transcription 1 [KO:K11220]
103746519  Stat2; signal transducer and activator of transcription 2 [KO:K11221]
103736155  Stat4; signal transducer and activator of transcription 4 [KO:K11222]
103742927  Stat6; signal transducer and activator of transcription 6 [KO:K11225]
103730772  Vegfa; vascular endothelial growth factor A [KO:K05448]
103738800  Vegfb; vascular endothelial growth factor B [KO:K16858]
103747350  Pgf; placental growth factor [KO:K16859]
103740292  Vegfd; vascular endothelial growth factor D [KO:K05449]
103745233  Vegfc; vascular endothelial growth factor C [KO:K05449]
103725901  Tgfa; transforming growth factor alpha [KO:K08774]
103742642  Egf; epidermal growth factor [KO:K04357]
103748852  epidermal growth factor receptor [KO:K04361] [EC:2.7.10.1]
103743825  Erbb2; erb-b2 receptor tyrosine kinase 2 [KO:K05083] [EC:2.7.10.1]
103748699  Pdgfa; platelet derived growth factor subunit A [KO:K04359]
103748570  Pdgfb; platelet derived growth factor subunit B [KO:K17386]
103734393  Pdgfra; platelet derived growth factor receptor alpha [KO:K04363] [EC:2.7.10.1]
103747076  Pdgfrb; platelet derived growth factor receptor beta [KO:K05089] [EC:2.7.10.1]
103733723  Igf1; insulin like growth factor 1 [KO:K05459]
103738988  Igf2; insulin like growth factor 2 [KO:K13769]
103749467  Igf1r; insulin like growth factor 1 receptor [KO:K05087] [EC:2.7.10.1]
103726473  Kitlg; KIT ligand [KO:K05461]
103734391  Kit; KIT proto-oncogene receptor tyrosine kinase [KO:K05091] [EC:2.7.10.1]
103743663  Flt3lg; fms related tyrosine kinase 3 ligand [KO:K05454]
103727235  Flt3; fms related tyrosine kinase 3 [KO:K05092] [EC:2.7.10.1]
103730723  Hgf; hepatocyte growth factor [KO:K05460]
103737431  Met; MET proto-oncogene, receptor tyrosine kinase [KO:K05099] [EC:2.7.10.1]
103736084  Fgf1; fibroblast growth factor 1 [KO:K18496]
103746947  Fgf2; fibroblast growth factor 2 [KO:K18497]
103733041  Fgf7; fibroblast growth factor 7 [KO:K04358]
103734036  Fgf10; fibroblast growth factor 10 [KO:K04358]
103737833  Fgf16; fibroblast growth factor 16 [KO:K04358]
103737403  Fgf22; fibroblast growth factor 22 [KO:K04358]
103742625  Fgf5; fibroblast growth factor 5 [KO:K04358]
103743281  Fgf20; fibroblast growth factor 20 [KO:K04358]
103744005  Fgf8; fibroblast growth factor 8 [KO:K04358]
103748184  Fgf18; fibroblast growth factor 18 [KO:K04358]
103751508  Fgf3; fibroblast growth factor 3 [KO:K04358]
103751500  Fgf4; fibroblast growth factor 4 [KO:K04358]
103747727  Fgf17; fibroblast growth factor 17 [KO:K04358]
103727190  Fgf9; fibroblast growth factor 9 [KO:K04358]
103727544  Fgf6; fibroblast growth factor 6 [KO:K04358]
103751507  Fgf19; fibroblast growth factor 19 [KO:K22603]
103743629  Fgf21; fibroblast growth factor 21 [KO:K22429]
103727545  Fgf23; fibroblast growth factor 23 [KO:K22428]
103745770  Fgfr1; fibroblast growth factor receptor 1 [KO:K04362] [EC:2.7.10.1]
103729272  Fgfr2; fibroblast growth factor receptor 2 [KO:K05093] [EC:2.7.10.1]
103741127  Fgfr3; fibroblast growth factor receptor 3 [KO:K05094] [EC:2.7.10.1]
103732354  Fgfr4; fibroblast growth factor receptor 4 [KO:K05095] [EC:2.7.10.1]
103732729  Grb2; growth factor receptor bound protein 2 [KO:K04364]
103743944  Sos1; SOS Ras/Rac guanine nucleotide exchange factor 1 [KO:K03099]
103731514  Sos2; SOS Ras/Rho guanine nucleotide exchange factor 2 [KO:K03099]
103751075  Hras; HRas proto-oncogene, GTPase [KO:K02833]
103736717  Kras; KRAS proto-oncogene, GTPase [KO:K07827]
103734938  Nras; neuroblastoma RAS viral oncogene homolog [KO:K07828]
103741627  Araf; A-Raf proto-oncogene, serine/threonine kinase [KO:K08845] [EC:2.7.11.1]
103726107  Braf; B-Raf proto-oncogene, serine/threonine kinase [KO:K04365] [EC:2.7.11.1]
103751450  Raf1; Raf-1 proto-oncogene, serine/threonine kinase [KO:K04366] [EC:2.7.11.1]
103736801  Map2k1; mitogen-activated protein kinase kinase 1 [KO:K04368] [EC:2.7.12.2]
103737276  Map2k2; mitogen-activated protein kinase kinase 2 [KO:K04369] [EC:2.7.12.2]
103741442  Mapk1; mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
103726390  Mapk3; mitogen-activated protein kinase 3 [KO:K04371] [EC:2.7.11.24]
103737138  Jun; Jun proto-oncogene, AP-1 transcription factor subunit [KO:K04448]
103747342  Fos; Fos proto-oncogene, AP-1 transcription factor subunit [KO:K04379]
103740682  Ets1; ETS proto-oncogene 1, transcription factor [KO:K02678]
103731579  interstitial collagenase A-like [KO:K01388] [EC:3.4.24.7]
103731678  interstitial collagenase-like [KO:K01388] [EC:3.4.24.7]
103731682  Mmp2; matrix metallopeptidase 2 [KO:K01398] [EC:3.4.24.24]
103751232  Mmp9; matrix metallopeptidase 9 [KO:K01403] [EC:3.4.24.35]
103742429  Cxcl8; C-X-C motif chemokine ligand 8 [KO:K10030]
103742900  Cdk4; cyclin dependent kinase 4 [KO:K02089] [EC:2.7.11.22]
103724612  Rps6ka5; ribosomal protein S6 kinase A5 [KO:K04445] [EC:2.7.11.1]
103733801  Ret; ret proto-oncogene [KO:K05126] [EC:2.7.10.1]
103746557  Ccdc6; coiled-coil domain containing 6 [KO:K09288]
103735006  Ncoa4; nuclear receptor coactivator 4 [KO:K09289]
103750263  Ntrk1; neurotrophic receptor tyrosine kinase 1 [KO:K03176] [EC:2.7.10.1]
103751563  Tpm3; tropomyosin 3 [KO:K09290]
103726654  Tpr; translocated promoter region, nuclear basket protein [KO:K09291]
103746345  Tfg; TRK-fused gene [KO:K09292]
103750153  Rassf1; Ras association domain family member 1 [KO:K09850]
103725938  Rassf5; Ras association domain family member 5 [KO:K08015]
103748401  Stk4; serine/threonine kinase 4 [KO:K04411]
103737271  Dapk3; death associated protein kinase 3 [KO:K08803] [EC:2.7.11.1]
103734199  Dapk1; death associated protein kinase 1 [KO:K08803] [EC:2.7.11.1]
103750086  Dapk2; death associated protein kinase 2 [KO:K08803] [EC:2.7.11.1]
103747244  Plcg1; phospholipase C gamma 1 [KO:K01116] [EC:3.1.4.11]
103748739  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 [KO:K05859] [EC:3.1.4.11]
103725694  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2-like [KO:K05859] [EC:3.1.4.11]
103741629  Elk1; ELK1, ETS transcription factor [KO:K04375]
103737134  Calml3; calmodulin like 3 [KO:K02183]
103737133  Calml5; calmodulin like 5 [KO:K02183]
103749800  Calml6; calmodulin like 6 [KO:K02183]
103724616  Calm1; calmodulin 1 [KO:K02183]
103724738  Calm3; calmodulin 3 [KO:K02183]
103725745  Calm2; calmodulin 2 [KO:K02183]
103729208  calmodulin-alpha-like [KO:K02183]
103736816  Calml4; calmodulin like 4 [KO:K02183]
103736933  Camk2g; calcium/calmodulin dependent protein kinase II gamma [KO:K04515] [EC:2.7.11.17]
103734983  Camk2b; calcium/calmodulin dependent protein kinase II beta [KO:K04515] [EC:2.7.11.17]
103743264  Camk2d; calcium/calmodulin dependent protein kinase II delta [KO:K04515] [EC:2.7.11.17]
103747079  Camk2a; calcium/calmodulin dependent protein kinase II alpha [KO:K04515] [EC:2.7.11.17]
103742830  Ralgds; ral guanine nucleotide dissociation stimulator [KO:K08732]
103736746  Rala; RAS like proto-oncogene A [KO:K07834]
103732313  Ralb; RAS like proto-oncogene B [KO:K07835]
103735424  Ralbp1; ralA binding protein 1 [KO:K08773]
103746394  Cdc42; cell division cycle 42 [KO:K04393]
103726484  Rac1; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) [KO:K04392]
103748617  Rac2; ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) [KO:K07860]
103752195  Pld2; phospholipase D2 [KO:K01115] [EC:3.1.4.4]
103731722  Pld1; phospholipase D1 [KO:K01115] [EC:3.1.4.4]
103735023  Mapk8; mitogen-activated protein kinase 8 [KO:K04440] [EC:2.7.11.24]
103748972  Mapk10; mitogen-activated protein kinase 10 [KO:K04440] [EC:2.7.11.24]
103749366  Mapk9; mitogen-activated protein kinase 9 [KO:K04440] [EC:2.7.11.24]
103750879  Pax8; paired box 8 [KO:K09293]
103751484  Pparg; peroxisome proliferator activated receptor gamma [KO:K08530]
103742823  Rxra; retinoid X receptor alpha [KO:K08524]
103739713  Rxrb; retinoid X receptor beta [KO:K08525]
103746119  Rxrg; retinoid X receptor gamma [KO:K08526]
103734263  Rarb; retinoic acid receptor beta [KO:K08528]
103745757  Esr1; estrogen receptor 1 [KO:K08550]
103747954  Esr2; estrogen receptor 2 [KO:K08551]
103746491  Ncoa1; nuclear receptor coactivator 1 [KO:K09101] [EC:2.3.1.48]
103729385  Ncoa3; nuclear receptor coactivator 3 [KO:K11256] [EC:2.3.1.48]
103738561  Sp1; Sp1 transcription factor [KO:K04684]
103739671  Ppard; peroxisome proliferator activated receptor delta [KO:K04504]
103735869  Jup; junction plakoglobin [KO:K10056]
103733862  Zbtb16; zinc finger and BTB domain containing 16 [KO:K10055]
103731122  Rara; retinoic acid receptor alpha [KO:K08527]
103746957  Ccna2; cyclin A2 [KO:K06627]
103731982  Ccna1; cyclin A1 [KO:K06627]
103736862  Pml; promyelocytic leukemia [KO:K10054] [EC:2.3.2.-]
103736431  Runx1; runt related transcription factor 1 [KO:K08367]
103729546  Runx1t1; RUNX1 translocation partner 1 [KO:K10053]
103742512  Spi1; Spi-1 proto-oncogene [KO:K09438]
103739150  Cebpa; CCAAT/enhancer binding protein alpha [KO:K09055]
103750113  granulocyte-macrophage colony-stimulating factor receptor subunit alpha-like [KO:K05066]
103733325  Csf3r; colony stimulating factor 3 receptor [KO:K05061]
103747075  Csf1r; colony stimulating factor 1 receptor [KO:K05090] [EC:2.7.10.1]
103730663  cyclin-dependent kinase 4 inhibitor B-like [KO:K06621]
103751571  E2f1; E2F transcription factor 1 [KO:K17454]
103746411  E2f2; E2F transcription factor 2 [KO:K09389]
103745641  E2f3; E2F transcription factor 3 [KO:K06620]
103749276  Max; MYC associated factor X [KO:K04453]
103725326  Zbtb17; zinc finger and BTB domain containing 17 [KO:K10500]
103730664  Cdkn2b; cyclin dependent kinase inhibitor 2B [KO:K04685]
103725210  Cdk6; cyclin dependent kinase 6 [KO:K02091] [EC:2.7.11.22]
103727547  Ccnd2; cyclin D2 [KO:K10151]
103725891  Ccnd3; cyclin D3 [KO:K10152]
103751221  Cks2; CDC28 protein kinase regulatory subunit 2 [KO:K02219]
103751243  Cks1b; CDC28 protein kinase regulatory subunit 1B [KO:K02219]
103729775  Skp1; S-phase kinase associated protein 1 [KO:K03094]
103731381  Cul1; cullin 1 [KO:K03347]
103743488  Rbx1; ring-box 1 [KO:K03868] [EC:2.3.2.32]
103741317  Skp2; S-phase kinase associated protein 2 [KO:K03875]
103746495  Cdk2; cyclin dependent kinase 2 [KO:K02206] [EC:2.7.11.22]
103740830  Ccne1; cyclin E1 [KO:K06626]
103745830  Ccne2; cyclin E2 [KO:K06626]
103726779  Rb1; RB transcriptional corepressor 1 [KO:K06618]
103737285  Gadd45b; growth arrest and DNA damage inducible beta [KO:K04402]
103743354  Gadd45a; growth arrest and DNA damage inducible alpha [KO:K04402]
103751225  Gadd45g; growth arrest and DNA damage inducible gamma [KO:K04402]
103743639  Bax; BCL2 associated X, apoptosis regulator [KO:K02159]
103739733  Bak1; BCL2 antagonist/killer 1 [KO:K14021]
103742505  Ddb2; damage specific DNA binding protein 2 [KO:K10140]
103736569  Polk; DNA polymerase kappa [KO:K03511] [EC:2.7.7.7]
103749674  Tert; telomerase reverse transcriptase [KO:K11126] [EC:2.7.7.49]
103729150  Mitf; melanogenesis associated transcription factor [KO:K09455]
103751514  Tgfb1; transforming growth factor beta 1 [KO:K13375]
103728817  Tgfb2; transforming growth factor beta 2 [KO:K13376]
103739777  Tgfb3; transforming growth factor beta 3 [KO:K13377]
103744902  Tgfbr1; transforming growth factor beta receptor 1 [KO:K04674] [EC:2.7.11.30]
103744639  Tgfbr2; transforming growth factor beta receptor 2 [KO:K04388] [EC:2.7.11.30]
103727836  Smad2; SMAD family member 2 [KO:K04500]
103736807  Smad3; SMAD family member 3 [KO:K23605]
103726635  Smad4; SMAD family member 4 [KO:K04501]
103731713  Mecom; MDS1 and EVI1 complex locus protein EVI1 [KO:K04462] [EC:2.1.1.367]
103741116  Ctbp1; C-terminal binding protein 1 [KO:K04496] [EC:1.1.1.428]
103744263  Ctbp2; C-terminal binding protein 2 [KO:K04496] [EC:1.1.1.428]
103733778  Hdac2; histone deacetylase 2 [KO:K06067] [EC:3.5.1.98]
103745919  Hdac1; histone deacetylase 1 [KO:K06067] [EC:3.5.1.98]
103731918  Mlh1; mutL homolog 1 [KO:K08734]
103725741  Msh2; mutS homolog 2 [KO:K08735]
103750270  Msh3; mutS homolog 3 [KO:K08736]
103725738  Msh6; mutS homolog 6 [KO:K08737]
103727209  Brca2; BRCA2, DNA repair associated [KO:K08775]
103744912  Rad51; RAD51 recombinase [KO:K04482]
103740694  Faslg; Fas ligand [KO:K04389]
103738053  Fas; Fas cell surface death receptor [KO:K04390]
103751502  Fadd; Fas associated via death domain [KO:K02373]
103738672  Casp8; caspase 8 [KO:K04398] [EC:3.4.22.61]
103745898  Bid; BH3 interacting domain death agonist [KO:K04726]
103739615  Pmaip1; phorbol-12-myristate-13-acetate-induced protein 1 [KO:K10131]
103724866  Bbc3; BCL2 binding component 3 [KO:K10132]
103750963  Bcl2l11; BCL2 like 11 [KO:K16341]
103740800  cytochrome c, somatic [KO:K08738]
103751785  cytochrome c, testis-specific [KO:K08738]
103733246  Apaf1; apoptotic peptidase activating factor 1 [KO:K02084]
103731752  Casp7; caspase 7 [KO:K04397] [EC:3.4.22.60]
103747559  Keap1; kelch like ECH associated protein 1 [KO:K10456]
103751782  Nfe2l2; nuclear factor, erythroid 2 like 2 [KO:K05638]
103742105  Hmox1; heme oxygenase 1 [KO:K00510] [EC:1.14.14.18]
103734696  Nqo1; NAD(P)H dehydrogenase [quinone] 1 [KO:K00355] [EC:1.6.5.2]
103734703  NAD(P)H dehydrogenase [quinone] 1-like [KO:K00355] [EC:1.6.5.2]
103734296  glutathione S-transferase theta-2-like [KO:K00799] [EC:2.5.1.18]
103738073  glutathione S-transferase theta-1-like [KO:K00799] [EC:2.5.1.18]
103740065  glutathione S-transferase theta-1-like [KO:K00799] [EC:2.5.1.18]
103734428  Mgst1; microsomal glutathione S-transferase 1 [KO:K00799] [EC:2.5.1.18]
103742372  Mgst2; microsomal glutathione S-transferase 2 [KO:K00799] [EC:2.5.1.18]
103744054  Gsto2; glutathione S-transferase omega 2 [KO:K00799] [EC:2.5.1.18]
103744053  Gsto1; glutathione S-transferase omega 1 [KO:K00799] [EC:2.5.1.18]
103744353  glutathione S-transferase A2-like [KO:K00799] [EC:2.5.1.18]
103744359  glutathione S-transferase A2-like [KO:K00799] [EC:2.5.1.18]
103748819  glutathione S-transferase theta-1-like [KO:K00799] [EC:2.5.1.18]
103747825  Gstm3; glutathione S-transferase mu 3 [KO:K00799] [EC:2.5.1.18]
103747828  glutathione S-transferase Mu 6 [KO:K00799] [EC:2.5.1.18]
103747829  glutathione S-transferase Mu 1 [KO:K00799] [EC:2.5.1.18]
103747827  glutathione S-transferase Mu 7 [KO:K00799] [EC:2.5.1.18]
103747826  glutathione S-transferase Mu 2-like [KO:K00799] [EC:2.5.1.18]
103747831  glutathione S-transferase Mu 2 [KO:K00799] [EC:2.5.1.18]
103747832  Gstm4; glutathione S-transferase Mu 1 [KO:K00799] [EC:2.5.1.18]
103746121  Mgst3; microsomal glutathione S-transferase 3 [KO:K00799] [EC:2.5.1.18]
103727361  glutathione S-transferase alpha-3 [KO:K00799] [EC:2.5.1.18]
103727364  glutathione S-transferase alpha-3-like [KO:K00799] [EC:2.5.1.18]
103727363  glutathione S-transferase-like [KO:K00799] [EC:2.5.1.18]
103727380  glutathione S-transferase A6 [KO:K00799] [EC:2.5.1.18]
103752503  glutathione S-transferase A6 [KO:K00799] [EC:2.5.1.18]
103752502  glutathione S-transferase A6-like [KO:K00799] [EC:2.5.1.18]
103727382  glutathione S-transferase alpha-3-like [KO:K00799] [EC:2.5.1.18]
103729179  glutathione S-transferase theta-1-like [KO:K00799] [EC:2.5.1.18]
103734295  glutathione S-transferase theta-4 [KO:K00799] [EC:2.5.1.18]
103725597  glutathione S-transferase P [KO:K23790] [EC:2.5.1.18]
103742138  Txnrd1; thioredoxin reductase 1 [KO:K22182] [EC:1.8.1.9]
103730360  Txnrd3; thioredoxin reductase 3 [KO:K22182] [EC:1.8.1.9]
103742058  Txnrd2; thioredoxin reductase 2 [KO:K22182] [EC:1.8.1.9]
103751433  Vhl; von Hippel-Lindau tumor suppressor [KO:K03871]
103746623  Eloc; elongin C [KO:K03872]
103744009  Elob; elongin B [KO:K03873]
103734786  Cul2; cullin 2 [KO:K03870]
103738632  Egln3; egl-9 family hypoxia inducible factor 3 [KO:K09592] [EC:1.14.11.29]
103744145  Egln1; egl-9 family hypoxia inducible factor 1 [KO:K09592] [EC:1.14.11.29]
103750775  Egln2; egl-9 family hypoxia inducible factor 2 [KO:K09592] [EC:1.14.11.29]
103746894  Fh; fumarate hydratase [KO:K01679] [EC:4.2.1.2]
103747967  Hif1a; hypoxia inducible factor 1 alpha subunit [KO:K08268]
103725756  Epas1; endothelial PAS domain protein 1 [KO:K09095]
103729101  Arnt; aryl hydrocarbon receptor nuclear translocator [KO:K09097]
103750348  Arnt2; aryl hydrocarbon receptor nuclear translocator 2 [KO:K15589]
103743486  Ep300; E1A binding protein p300 [KO:K04498] [EC:2.3.1.48]
103744441  Crebbp; CREB binding protein [KO:K04498] [EC:2.3.1.48]
103741911  Slc2a1; solute carrier family 2 member 1 [KO:K07299]
103729189  Jag1; jagged 1 [KO:K06052]
103752541  Jag2; jagged 2 [KO:K21635]
103744923  Dll4; delta like canonical Notch ligand 4 [KO:K06051]
103742345  Dll1; delta like canonical Notch ligand 1 [KO:K06051]
103750746  Dll3; delta like canonical Notch ligand 3 [KO:K06051]
103741215  Notch1; notch 1 [KO:K02599]
103732001  Notch2; notch 2 [KO:K20994]
103731622  Notch3; notch 3 [KO:K20995]
103724403  Notch4; notch 4 [KO:K20996]
103738854  Hes1; hes family bHLH transcription factor 1 [KO:K06054]
103749777  Hes5; hes family bHLH transcription factor 5 [KO:K06055]
103736697  Heyl; hes related family bHLH transcription factor with YRPW motif-like [KO:K09091]
103746526  Hey2; hes related family bHLH transcription factor with YRPW motif 2 [KO:K09091]
103727947  Hey1; hes related family bHLH transcription factor with YRPW motif 1 [KO:K09091]
103749361  Flt4; fms related tyrosine kinase 4 [KO:K05097] [EC:2.7.10.1]
103745341  Shh; sonic hedgehog [KO:K11988]
103751618  protein patched homolog 1 [KO:K06225]
103744549  Smo; smoothened, frizzled class receptor [KO:K06226]
103749908  Kif7; kinesin family member 7 [KO:K18806]
103744025  Sufu; SUFU negative regulator of hedgehog signaling [KO:K06229]
103742914  Gli1; GLI family zinc finger 1 [KO:K16797]
103732312  Gli2; GLI family zinc finger 2 [KO:K16798]
103736753  Gli3; GLI family zinc finger 3 [KO:K06230]
103725543  Bmp2; bone morphogenetic protein 2 [KO:K21283]
103739231  Bmp4; bone morphogenetic protein 4 [KO:K04662]
103745995  Hhip; hedgehog interacting protein [KO:K06231]
103746594  Ptch2; patched 2 [KO:K11101]
103743142  Ar; androgen receptor [KO:K08557]
103740779  heat shock protein HSP 90-beta-like [KO:K04079]
103727631  Hsp90aa1; heat shock protein 90 alpha family class A member 1 [KO:K04079]
103730766  Hsp90ab1; heat shock protein 90 alpha family class B member 1 [KO:K04079]
103742145  Hsp90b1; heat shock protein 90 beta family member 1 [KO:K09487]
103724966  endoplasmin-like [KO:K09487]
Compound
C00027  Hydrogen peroxide
C00039  DNA
C00076  Calcium cation
C00122  Fumarate
C00149  (S)-Malate
C00165  Diacylglycerol
C00187  Cholesterol
C00280  Androstenedione
C00410  Progesterone
C00416  Phosphatidate
C00533  Nitric oxide
C00535  Testosterone
C00575  3',5'-Cyclic AMP
C00584  Prostaglandin E2
C00681  1-Acyl-sn-glycerol 3-phosphate
C00704  Superoxide
C00735  Cortisol
C00762  Cortisone
C00777  Retinoate
C00951  Estradiol-17beta
C01227  Dehydroepiandrosterone
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01471  Acrolein
C03917  Dihydrotestosterone
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C07653  Flutamide
C15493  9-cis-Retinoic acid
C16038  2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
C16844  Hydroxyl radical
C21641  Hydroperoxyl radical
C21642  4-Hydroxynonenal
Reference
  Authors
Weinberg RA.
  Title
The biology of cancer
  Journal
Garland Science, Taylor & Francis Group, LLC (2007)
Reference
  Authors
Hanahan D, Weinberg RA
  Title
The hallmarks of cancer.
  Journal
Cell 100:57-70 (2000)
DOI:10.1016/S0092-8674(00)81683-9
Reference
  Authors
Grady WM.
  Title
Genomic instability and colon cancer.
  Journal
Cancer Metastasis Rev 23:11-27 (2004)
DOI:10.1023/A:1025861527711
Reference
  Authors
Soreide K, Janssen EA, Soiland H, Korner H, Baak JP.
  Title
Microsatellite instability in colorectal cancer.
  Journal
Br J Surg 93:395-406 (2006)
DOI:10.1002/bjs.5328
Reference
  Authors
Anwar S, Hall C, White J, Deakin M, Farrell W, Elder JB.
  Title
Hereditary non-polyposis colorectal cancer: an updated review.
  Journal
Eur J Surg Oncol 26:635-45 (2000)
DOI:10.1053/ejso.2000.0974
Reference
  Authors
Takayama T, Miyanishi K, Hayashi T, Sato Y, Niitsu Y.
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pathway
ngi03320  PPAR signaling pathway
ngi04010  MAPK signaling pathway
ngi04020  Calcium signaling pathway
ngi04024  cAMP signaling pathway
ngi04060  Cytokine-cytokine receptor interaction
ngi04066  HIF-1 signaling pathway
ngi04110  Cell cycle
ngi04115  p53 signaling pathway
ngi04150  mTOR signaling pathway
ngi04151  PI3K-Akt signaling pathway
ngi04210  Apoptosis
ngi04310  Wnt signaling pathway
ngi04330  Notch signaling pathway
ngi04340  Hedgehog signaling pathway
ngi04350  TGF-beta signaling pathway
ngi04370  VEGF signaling pathway
ngi04510  Focal adhesion
ngi04512  ECM-receptor interaction
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KO pathway
ko05200   
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