KEGG   PATHWAY: cjc05200
Entry
cjc05200                    Pathway                                
Name
Pathways in cancer - Callithrix jacchus (white-tufted-ear marmoset)
Class
Human Diseases; Cancer: overview
Pathway map
cjc05200  Pathways in cancer
cjc05200

Organism
Callithrix jacchus (white-tufted-ear marmoset) [GN:cjc]
Gene
100410745  DCC; netrin receptor DCC isoform X1 [KO:K06765]
100387570  CASP3; caspase-3 isoform X2 [KO:K02187] [EC:3.4.22.56]
100409028  CASP9; caspase-9 isoform X3 [KO:K04399] [EC:3.4.22.62]
100389847  APPL1; DCC-interacting protein 13-alpha [KO:K08733]
100398679  CDH1; cadherin-1 [KO:K05689]
100395047  CTNNB1; catenin beta-1 isoform X1 [KO:K02105]
100390556  CTNNA2; catenin alpha-2 isoform X6 [KO:K05691]
100396596  CTNNA3; catenin alpha-3 isoform X1 [KO:K05691]
100407624  CTNNA1; catenin alpha-1 isoform X2 [KO:K05691]
100392475  AXIN1; axin-1 isoform X1 [KO:K02157]
100400518  AXIN2; axin-2 isoform X1 [KO:K04385]
100397972  APC2; adenomatous polyposis coli protein 2 isoform X2 [KO:K02085]
100385653  APC; adenomatous polyposis coli protein isoform X1 [KO:K02085]
100387683  GSK3B; glycogen synthase kinase-3 beta isoform X1 [KO:K03083] [EC:2.7.11.26]
100399154  TCF7; transcription factor 7 isoform X2 [KO:K02620]
100403963  TCF7L1; transcription factor 7-like 1 isoform X2 [KO:K04490]
100406757  TCF7L2; transcription factor 7-like 2 isoform X1 [KO:K04491]
100399759  LEF1; lymphoid enhancer-binding factor 1 isoform X5 [KO:K04492]
100398121  BIRC5; baculoviral IAP repeat-containing protein 5 isoform X2 [KO:K08731]
100407754  MYC; myc proto-oncogene protein [KO:K04377]
103796419  CCND1; G1/S-specific cyclin-D1 [KO:K04503]
100389319  WNT1; proto-oncogene Wnt-1 [KO:K03209]
100395234  WNT2B; protein Wnt-2b [KO:K00182]
100411308  WNT2; protein Wnt-2 [KO:K00182]
100385309  WNT3A; protein Wnt-3a [KO:K00312]
100398579  WNT3; proto-oncogene Wnt-3 [KO:K00312]
100387135  WNT4; protein Wnt-4 [KO:K00408]
100401066  WNT5A; protein Wnt-5a isoform X2 [KO:K00444]
100405273  WNT5B; protein Wnt-5b [KO:K00444]
100394855  WNT6; protein Wnt-6 [KO:K00445]
100414221  WNT7B; protein Wnt-7b isoform X2 [KO:K00572]
100387909  WNT7A; protein Wnt-7a [KO:K00572]
100414921  WNT8B; protein Wnt-8b [KO:K00714]
100402422  WNT8A; protein Wnt-8a [KO:K00714]
100397032  WNT9A; protein Wnt-9a isoform X2 [KO:K01064]
100393646  WNT9B; protein Wnt-9b [KO:K01064]
100395222  WNT10A; protein Wnt-10a [KO:K01357]
100388949  WNT10B; protein Wnt-10b [KO:K01357]
100398625  WNT11; protein Wnt-11 isoform X1 [KO:K01384]
100387388  WNT16; protein Wnt-16 isoform X1 [KO:K01558]
100401631  FZD7; frizzled-7 [KO:K02432]
100404550  FZD1; frizzled-1 [KO:K02432]
100409481  FZD2; frizzled-2 [KO:K02235]
100396334  FZD3; frizzled-3 isoform X1 [KO:K02329]
100403228  FZD4; frizzled-4 isoform X1 [KO:K02354]
100410939  FZD5; frizzled-5 [KO:K02375]
100398598  FZD8; frizzled-8 [KO:K02375]
100387077  FZD6; frizzled-6 [KO:K02376]
100403975  FZD9; frizzled-9 [KO:K02842]
100398976  FZD10; frizzled-10 [KO:K02842]
100406268  LRP5; low-density lipoprotein receptor-related protein 5 isoform X1 [KO:K03068]
100389922  LRP6; low-density lipoprotein receptor-related protein 6 isoform X1 [KO:K03068]
100390081  DVL3; segment polarity protein dishevelled homolog DVL-3 isoform X1 [KO:K02353]
100398229  DVL2; segment polarity protein dishevelled homolog DVL-2 isoform X1 [KO:K02353]
100388569  DVL1; segment polarity protein dishevelled homolog DVL-1 isoform X3 [KO:K02353]
118154524  LOW QUALITY PROTEIN: segment polarity protein dishevelled homolog DVL-1-like [KO:K02353]
108594172  FRAT1; proto-oncogene FRAT1 [KO:K03069]
100407124  FRAT2; GSK-3-binding protein FRAT2 [KO:K03096]
100386446  F2; prothrombin [KO:K01313] [EC:3.4.21.5]
100389395  AGT; angiotensinogen precursor [KO:K09821]
100400356  F2R; proteinase-activated receptor 1 [KO:K03914]
100396997  F2RL3; proteinase-activated receptor 4 [KO:K04236]
100414340  LPAR1; lysophosphatidic acid receptor 1 isoform X1 [KO:K04289]
100391457  LPAR2; lysophosphatidic acid receptor 2 [KO:K04291]
100392576  LPAR3; lysophosphatidic acid receptor 3 [KO:K04294]
100395819  LPAR4; lysophosphatidic acid receptor 4 [KO:K04275]
100413340  LPAR5; lysophosphatidic acid receptor 5 [KO:K08390]
100398639  LPAR6; lysophosphatidic acid receptor 6 [KO:K04273]
100406419  AGTR1; type-1 angiotensin II receptor [KO:K04166]
100387912  GNA12; guanine nucleotide-binding protein subunit alpha-12 [KO:K04346]
100394016  GNA13; guanine nucleotide-binding protein subunit alpha-13 isoform X1 [KO:K04639]
100411450  ARHGEF12; rho guanine nucleotide exchange factor 12 isoform X1 [KO:K07532]
100389507  ARHGEF11; rho guanine nucleotide exchange factor 11 isoform X5 [KO:K12331]
100409602  ARHGEF1; LOW QUALITY PROTEIN: rho guanine nucleotide exchange factor 1 [KO:K12330]
100391235  PLEKHG5; pleckstrin homology domain-containing family G member 5 isoform X2 [KO:K19464]
100393236  RHOA; transforming protein RhoA [KO:K04513]
100404129  transforming protein RhoA-like [KO:K04513]
100394652  ROCK1; rho-associated protein kinase 1 isoform X1 [KO:K04514] [EC:2.7.11.1]
100408337  ROCK2; rho-associated protein kinase 2 isoform X1 [KO:K17388] [EC:2.7.11.1]
100402880  CXCL12; stromal cell-derived factor 1 isoform X1 [KO:K10031]
100406954  CXCR4; C-X-C chemokine receptor type 4 [KO:K04189]
100404474  GNAI2; guanine nucleotide-binding protein G(i) subunit alpha-2 isoform X1 [KO:K04630]
100405745  GNAI3; guanine nucleotide-binding protein G(i) subunit alpha-3 isoform X1 [KO:K04630]
100388113  GNAI1; guanine nucleotide-binding protein G(i) subunit alpha-1 [KO:K04630]
100396387  PTGER1; prostaglandin E2 receptor EP1 subtype [KO:K04258]
100394168  PTGER2; prostaglandin E2 receptor EP2 subtype [KO:K04259]
108590441  PTGER3; prostaglandin E2 receptor EP3 subtype isoform X1 [KO:K04260]
100410649  PTGER4; prostaglandin E2 receptor EP4 subtype [KO:K04261]
100408515  GNAS; guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas isoform X2 [KO:K04632]
103787209  neuroendocrine secretory protein 55 [KO:K04632]
100394265  ADCY1; adenylate cyclase type 1 [KO:K08041] [EC:4.6.1.1]
100385658  ADCY2; adenylate cyclase type 2 [KO:K08042] [EC:4.6.1.1]
100415165  ADCY3; adenylate cyclase type 3 isoform X1 [KO:K08043] [EC:4.6.1.1]
100415141  ADCY4; adenylate cyclase type 4 isoform X1 [KO:K08044] [EC:4.6.1.1]
100412782  ADCY5; adenylate cyclase type 5 isoform X1 [KO:K08045] [EC:4.6.1.1]
100406617  ADCY6; adenylate cyclase type 6 isoform X1 [KO:K08046] [EC:4.6.1.1]
100404620  ADCY7; adenylate cyclase type 7 isoform X1 [KO:K08047] [EC:4.6.1.1]
100404484  ADCY8; adenylate cyclase type 8 isoform X1 [KO:K08048] [EC:4.6.1.1]
100405403  ADCY9; adenylate cyclase type 9 isoform X2 [KO:K08049] [EC:4.6.1.1]
100392123  PRKACG; LOW QUALITY PROTEIN: cAMP-dependent protein kinase catalytic subunit gamma [KO:K04345] [EC:2.7.11.11]
100408115  cAMP-dependent protein kinase catalytic subunit gamma-like [KO:K04345] [EC:2.7.11.11]
100407692  PRKACB; cAMP-dependent protein kinase catalytic subunit beta isoform X1 [KO:K04345] [EC:2.7.11.11]
100400737  PRKACA; LOW QUALITY PROTEIN: cAMP-dependent protein kinase catalytic subunit alpha [KO:K04345] [EC:2.7.11.11]
100409206  cAMP-dependent protein kinase catalytic subunit gamma-like [KO:K04345] [EC:2.7.11.11]
118151333  cAMP-dependent protein kinase catalytic subunit alpha-like [KO:K04345] [EC:2.7.11.11]
100412968  GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 isoform X2 [KO:K04536]
100395033  GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 [KO:K04537]
100407336  GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 [KO:K07825]
100395633  GNB4; guanine nucleotide-binding protein subunit beta-4 isoform X1 [KO:K04538]
100415506  GNB5; guanine nucleotide-binding protein subunit beta-5 isoform X2 [KO:K04539]
100391372  GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 [KO:K07826]
100397915  GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 [KO:K04540]
100411028  GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 [KO:K04541]
103787193  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 [KO:K04542]
108590740  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5-like [KO:K04542]
108593490  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5-like [KO:K04542]
118150544  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5-like [KO:K04542]
128930422  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 [KO:K04542]
100411155  GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 [KO:K04543]
108589488  GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 [KO:K04544]
100385281  GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 [KO:K04545]
108588980  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10-like [KO:K04545]
100412160  GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 [KO:K04546]
100396640  GNG14; LOW QUALITY PROTEIN: putative guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-14 [KO:K04347]
100394978  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 [KO:K04347]
108594009  GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 [KO:K04547]
100412503  GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1 [KO:K04548]
100394732  GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 [KO:K04549]
100405184  COL4A2; collagen alpha-2(IV) chain [KO:K06237]
100400812  COL4A1; collagen alpha-1(IV) chain [KO:K06237]
100388823  COL4A3; collagen alpha-3(IV) chain isoform X1 [KO:K06237]
100388461  COL4A4; collagen alpha-4(IV) chain [KO:K06237]
100409842  COL4A5; collagen alpha-5(IV) chain isoform X1 [KO:K06237]
100394953  COL4A6; collagen alpha-6(IV) chain isoform X1 [KO:K06237]
100403734  LAMA1; laminin subunit alpha-1 isoform X1 [KO:K05637]
100405831  LAMA2; laminin subunit alpha-2 isoform X1 [KO:K05637]
100401798  LAMA3; LOW QUALITY PROTEIN: laminin subunit alpha-3 [KO:K06240]
103792989  LAMA5; LOW QUALITY PROTEIN: laminin subunit alpha-5 [KO:K06240]
100396274  LAMA4; laminin subunit alpha-4 isoform X1 [KO:K06241]
100400907  LAMB1; laminin subunit beta-1 [KO:K05636]
100389118  LAMB2; laminin subunit beta-2 isoform X1 [KO:K06243]
100400492  LAMB3; laminin subunit beta-3 [KO:K06244]
100401649  LAMB4; laminin subunit beta-4 [KO:K06245]
100401710  LAMC1; laminin subunit gamma-1 [KO:K05635]
100401336  LAMC2; laminin subunit gamma-2 [KO:K06246]
100403136  LAMC3; laminin subunit gamma-3 isoform X1 [KO:K06247]
100405983  FN1; fibronectin isoform X2 [KO:K05717]
100403636  ITGA2; integrin alpha-2 isoform X1 [KO:K06481]
100408748  ITGA2B; integrin alpha-IIb [KO:K06476]
100386753  ITGA3; integrin alpha-3 isoform X1 [KO:K06482]
100403557  ITGA6; integrin alpha-6 isoform X7 [KO:K06485]
100389906  ITGAV; integrin alpha-V [KO:K06487]
100394145  ITGB1; integrin beta-1 isoform X1 [KO:K05719]
100395283  PTK2; focal adhesion kinase 1 isoform X9 [KO:K05725] [EC:2.7.10.2]
100403494  PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
100391655  PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X2 [KO:K00922] [EC:2.7.1.153]
100398849  PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
100406689  PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta [KO:K02649]
100392639  PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X2 [KO:K02649]
100414659  PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma isoform X2 [KO:K02649]
100393460  PTEN; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
100412294  NKX3-1; homeobox protein Nkx-3.1 [KO:K09348]
100404447  AKT1; RAC-alpha serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
100399039  AKT3; RAC-gamma serine/threonine-protein kinase isoform X6 [KO:K04456] [EC:2.7.11.1]
100388080  AKT2; RAC-beta serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
100393096  IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta isoform X2 [KO:K07209] [EC:2.7.11.10]
100390258  IKBKG; NF-kappa-B essential modulator isoform X1 [KO:K07210]
100402266  NFKBIA; NF-kappa-B inhibitor alpha [KO:K04734]
100415321  NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1 [KO:K02580]
100395882  NFKB2; nuclear factor NF-kappa-B p100 subunit isoform X1 [KO:K04469]
100388493  RELA; transcription factor p65 isoform X1 [KO:K04735]
100407639  PTGS2; prostaglandin G/H synthase 2 [KO:K11987] [EC:1.14.99.1]
100403192  NOS2; nitric oxide synthase, inducible isoform X1 [KO:K13241] [EC:1.14.13.39]
100408947  BCL2; apoptosis regulator Bcl-2 [KO:K02161]
100394418  BIRC2; baculoviral IAP repeat-containing protein 2 isoform X1 [KO:K16060]
100399118  BIRC3; baculoviral IAP repeat-containing protein 3 isoform X1 [KO:K16060]
100402341  XIAP; E3 ubiquitin-protein ligase XIAP [KO:K04725] [EC:2.3.2.27]
100396394  BIRC7; baculoviral IAP repeat-containing protein 7 isoform X1 [KO:K16061]
100401978  BCL2L1; bcl-2-like protein 1 [KO:K04570]
100389116  TRAF1; TNF receptor-associated factor 1 [KO:K03172]
100404226  TRAF2; TNF receptor-associated factor 2 [KO:K03173] [EC:2.3.2.27]
100387401  TRAF3; TNF receptor-associated factor 3 isoform X1 [KO:K03174]
100404035  TRAF4; TNF receptor-associated factor 4 isoform X1 [KO:K09848]
100388423  TRAF5; TNF receptor-associated factor 5 isoform X3 [KO:K09849]
100395364  TRAF6; TNF receptor-associated factor 6 isoform X2 [KO:K03175] [EC:2.3.2.27]
100406608  MTOR; serine/threonine-protein kinase mTOR [KO:K07203] [EC:2.7.11.1]
100397180  RPS6KB2; ribosomal protein S6 kinase beta-2 [KO:K04688] [EC:2.7.11.1]
100409247  RPS6KB1; ribosomal protein S6 kinase beta-1 isoform X3 [KO:K04688] [EC:2.7.11.1]
100412880  BAD; bcl2-associated agonist of cell death isoform X2 [KO:K02158]
100397393  FOXO1; forkhead box protein O1 [KO:K07201]
100415620  E3 ubiquitin-protein ligase Mdm2 isoform X1 [KO:K06643] [EC:2.3.2.27]
100396301  E3 ubiquitin-protein ligase Mdm2-like isoform X1 [KO:K06643] [EC:2.3.2.27]
100415710  TP53; cellular tumor antigen p53 isoform X1 [KO:K04451]
100387508  CDKN1B; cyclin-dependent kinase inhibitor 1B [KO:K06624]
100894215  CDKN1A; cyclin-dependent kinase inhibitor 1 [KO:K06625]
100393591  breakpoint cluster region protein isoform X2 [KO:K08878] [EC:2.7.11.1]
100398414  ABL1; tyrosine-protein kinase ABL1 isoform X1 [KO:K06619] [EC:2.7.10.2]
100390206  CRKL; crk-like protein [KO:K04438]
100399916  CRK; adapter molecule crk isoform X1 [KO:K04438]
100408313  CBL; E3 ubiquitin-protein ligase CBL isoform X2 [KO:K04707] [EC:2.3.2.27]
100388917  STAT5A; signal transducer and activator of transcription 5A isoform X1 [KO:K11223]
100388552  STAT5B; signal transducer and activator of transcription 5B isoform X1 [KO:K11224]
100391311  PIM1; serine/threonine-protein kinase pim-1 [KO:K04702] [EC:2.7.11.1]
100404269  PIM2; serine/threonine-protein kinase pim-2 [KO:K08806] [EC:2.7.11.1]
100405422  KNG1; kininogen-1 [KO:K03898]
100414848  EDN1; endothelin-1 [KO:K16366]
100407472  BDKRB1; B1 bradykinin receptor [KO:K03915]
100399591  BDKRB2; B2 bradykinin receptor [KO:K03916]
100410292  EDNRA; endothelin-1 receptor isoform X1 [KO:K04197]
100412645  EDNRB; endothelin receptor type B [KO:K04198]
100403006  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha isoform X2 [KO:K04634]
100386734  GNA11; guanine nucleotide-binding protein subunit alpha-11 isoform X1 [KO:K04635]
100400803  PLCB3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 isoform X1 [KO:K05858] [EC:3.1.4.11]
100386921  PLCB2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X1 [KO:K05858] [EC:3.1.4.11]
100409716  PLCB1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X1 [KO:K05858] [EC:3.1.4.11]
100410075  PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X3 [KO:K05858] [EC:3.1.4.11]
100391814  PRKCA; protein kinase C alpha type [KO:K02677] [EC:2.7.11.13]
100410136  PRKCB; protein kinase C beta type isoform X1 [KO:K19662] [EC:2.7.11.13]
100404028  PRKCG; protein kinase C gamma type isoform X1 [KO:K19663] [EC:2.7.11.13]
100386848  IL2; interleukin-2 [KO:K05429]
100406536  IL4; interleukin-4 precursor [KO:K05430]
100407630  IL5; interleukin-5 precursor [KO:K05428]
100393440  IL6; interleukin-6 precursor [KO:K05405]
100387798  IL7; interleukin-7 [KO:K05431]
100406669  IL12A; interleukin-12 subunit alpha [KO:K05406]
100395403  IL12B; interleukin-12 subunit beta [KO:K05425]
100406899  IL13; interleukin-13 precursor [KO:K05435]
100409575  IL15; interleukin-15 isoform X1 [KO:K05433]
100414179  IL23A; interleukin-23 subunit alpha isoform X2 [KO:K05426]
100394313  EPO; erythropoietin [KO:K05437]
100414516  interferon alpha-1/13-like [KO:K05414]
100390201  interferon alpha-5-like [KO:K05414]
100406098  interferon alpha-5-like [KO:K05414]
100406466  interferon alpha-14 [KO:K05414]
100387372  interferon alpha-5-like [KO:K05414]
103793369  interferon alpha-5-like [KO:K05414]
128928158  interferon alpha-14-like [KO:K05414]
128932203  interferon alpha-5-like [KO:K05414]
100388952  IFNG; interferon gamma precursor [KO:K04687]
100412016  IL2RA; interleukin-2 receptor subunit alpha precursor [KO:K05068]
100394910  IL2RB; interleukin-2 receptor subunit beta [KO:K05069]
100388189  IL2RG; cytokine receptor common subunit gamma precursor [KO:K05070]
100405472  interleukin-3 receptor subunit alpha isoform X1 [KO:K04737]
100412639  IL4R; interleukin-4 receptor subunit alpha precursor [KO:K05071]
100393477  CSF2RB; cytokine receptor common subunit beta isoform X1 [KO:K04738]
100414222  IL5RA; interleukin-5 receptor subunit alpha precursor [KO:K05067]
100385661  IL6R; interleukin-6 receptor subunit alpha precursor [KO:K05055]
100396729  IL6ST; interleukin-6 receptor subunit beta precursor [KO:K05060]
100397720  IL7R; interleukin-7 receptor subunit alpha isoform X1 [KO:K05072]
100399291  IL12RB1; interleukin-12 receptor subunit beta-1 isoform X1 [KO:K05063]
100393796  IL12RB2; interleukin-12 receptor subunit beta-2 [KO:K05064]
100385087  IL13RA1; interleukin-13 receptor subunit alpha-1 [KO:K05076]
100413804  IL15RA; LOW QUALITY PROTEIN: interleukin-15 receptor subunit alpha [KO:K05074]
100393072  IL23R; interleukin-23 receptor [KO:K05065]
100389634  EPOR; erythropoietin receptor isoform X1 [KO:K05079]
100410306  IFNAR1; interferon alpha/beta receptor 1 isoform X1 [KO:K05130]
128928024  IFNAR2; interferon alpha/beta receptor 2 isoform X2 [KO:K05131]
100386516  IFNGR1; interferon gamma receptor 1 isoform X1 [KO:K05132]
100389763  IFNGR2; interferon gamma receptor 2 [KO:K05133]
100410033  EML4; echinoderm microtubule-associated protein-like 4 isoform X2 [KO:K15420]
100399252  ALK; ALK tyrosine kinase receptor isoform X1 [KO:K05119] [EC:2.7.10.1]
100390905  RASGRP1; RAS guanyl-releasing protein 1 isoform X1 [KO:K04350]
100896269  RASGRP2; RAS guanyl-releasing protein 2 isoform X2 [KO:K12361]
100404102  RASGRP3; ras guanyl-releasing protein 3 isoform X1 [KO:K12362]
103789934  RASGRP4; RAS guanyl-releasing protein 4 isoform X1 [KO:K12363]
100385835  JAK1; tyrosine-protein kinase JAK1 isoform X1 [KO:K11217] [EC:2.7.10.2]
100413251  JAK2; tyrosine-protein kinase JAK2 [KO:K04447] [EC:2.7.10.2]
100397491  JAK3; tyrosine-protein kinase JAK3 isoform X1 [KO:K11218] [EC:2.7.10.2]
100389282  STAT3; signal transducer and activator of transcription 3 isoform X1 [KO:K04692]
100401630  STAT1; signal transducer and activator of transcription 1-alpha/beta [KO:K11220]
100393190  STAT2; signal transducer and activator of transcription 2 isoform X1 [KO:K11221]
100402355  STAT4; signal transducer and activator of transcription 4 isoform X1 [KO:K11222]
100390285  STAT6; signal transducer and activator of transcription 6 [KO:K11225]
100389629  VEGFA; vascular endothelial growth factor A isoform X1 [KO:K05448]
100400081  VEGFB; vascular endothelial growth factor B isoform X1 [KO:K16858]
100386568  PGF; placenta growth factor isoform X1 [KO:K16859]
100395294  VEGFC; vascular endothelial growth factor C isoform X1 [KO:K05449]
100407908  VEGFD; vascular endothelial growth factor D isoform X1 [KO:K05449]
100402888  TGFA; protransforming growth factor alpha isoform X1 [KO:K08774]
100388651  EGF; pro-epidermal growth factor isoform X1 [KO:K04357]
100412158  EGFR; epidermal growth factor receptor isoform X1 [KO:K04361] [EC:2.7.10.1]
100391332  ERBB2; receptor tyrosine-protein kinase erbB-2 isoform X1 [KO:K05083] [EC:2.7.10.1]
100412906  PDGFA; platelet-derived growth factor subunit A isoform X4 [KO:K04359]
100388628  PDGFB; platelet-derived growth factor subunit B isoform X1 [KO:K17386]
100412331  PDGFRA; platelet-derived growth factor receptor alpha precursor [KO:K04363] [EC:2.7.10.1]
100389852  PDGFRB; platelet-derived growth factor receptor beta [KO:K05089] [EC:2.7.10.1]
100394985  IGF1; insulin-like growth factor I isoform X2 [KO:K05459]
100393815  IGF2; insulin-like growth factor II isoform X2 [KO:K13769]
100408399  IGF1R; insulin-like growth factor 1 receptor isoform X3 [KO:K05087] [EC:2.7.10.1]
100410844  KITLG; kit ligand isoform X1 [KO:K05461]
103790554  kit ligand-like [KO:K05461]
100411615  KIT; mast/stem cell growth factor receptor Kit precursor [KO:K05091] [EC:2.7.10.1]
100411269  FLT3LG; fms-related tyrosine kinase 3 ligand isoform X11 [KO:K05454]
100413316  FLT3; receptor-type tyrosine-protein kinase FLT3 isoform X1 [KO:K05092] [EC:2.7.10.1]
100385966  HGF; hepatocyte growth factor isoform X2 [KO:K05460]
100408551  MET; hepatocyte growth factor receptor [KO:K05099] [EC:2.7.10.1]
100392014  FGF1; fibroblast growth factor 1 isoform X1 [KO:K18496]
118152209  FGF2; fibroblast growth factor 2 isoform X1 [KO:K18497]
100398595  fibroblast growth factor 6-like [KO:K04358]
100405886  FGF7; fibroblast growth factor 7 [KO:K04358]
100409540  FGF4; fibroblast growth factor 4 [KO:K04358]
100401797  FGF17; fibroblast growth factor 17 isoform X1 [KO:K04358]
100410253  FGF3; fibroblast growth factor 3 [KO:K04358]
100385862  FGF20; fibroblast growth factor 20 [KO:K04358]
100386978  FGF5; fibroblast growth factor 5 isoform X1 [KO:K04358]
100402660  FGF18; fibroblast growth factor 18 isoform X2 [KO:K04358]
100387695  FGF10; fibroblast growth factor 10 [KO:K04358]
100414371  FGF22; fibroblast growth factor 22 isoform X3 [KO:K04358]
100392792  FGF9; fibroblast growth factor 9 [KO:K04358]
100390531  FGF6; fibroblast growth factor 6 [KO:K04358]
100388550  FGF16; fibroblast growth factor 16 [KO:K04358]
128929061  FGF19; fibroblast growth factor 19 [KO:K22603]
100389889  FGF21; fibroblast growth factor 21 [KO:K22429]
100392707  FGF23; fibroblast growth factor 23 [KO:K22428]
100390192  FGFR1; fibroblast growth factor receptor 1 isoform X5 [KO:K04362] [EC:2.7.10.1]
100393573  FGFR2; fibroblast growth factor receptor 2 isoform X3 [KO:K05093] [EC:2.7.10.1]
100409938  FGFR3; fibroblast growth factor receptor 3 isoform X1 [KO:K05094] [EC:2.7.10.1]
100414348  FGFR4; fibroblast growth factor receptor 4 isoform X1 [KO:K05095] [EC:2.7.10.1]
100395682  GRB2; growth factor receptor-bound protein 2 [KO:K04364]
100414931  SOS1; son of sevenless homolog 1 isoform X1 [KO:K03099]
100410124  SOS2; son of sevenless homolog 2 isoform X1 [KO:K03099]
100406017  HRAS; GTPase HRas [KO:K02833]
118144179  KRAS; GTPase KRas isoform X2 [KO:K07827]
100414782  NRAS; GTPase NRas isoform X2 [KO:K07828]
108591807  GTPase NRas-like [KO:K07828]
100387961  ARAF; serine/threonine-protein kinase A-Raf isoform X1 [KO:K08845] [EC:2.7.11.1]
100403091  BRAF; serine/threonine-protein kinase B-raf isoform X2 [KO:K04365] [EC:2.7.11.1]
100415300  RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X1 [KO:K04366] [EC:2.7.11.1]
100387394  MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 isoform X1 [KO:K04368] [EC:2.7.12.2]
100393991  MAP2K2; dual specificity mitogen-activated protein kinase kinase 2 [KO:K04369] [EC:2.7.12.2]
100400700  MAPK1; mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
100404815  MAPK3; mitogen-activated protein kinase 3 [KO:K04371] [EC:2.7.11.24]
100400411  JUN; transcription factor Jun [KO:K04448]
100390054  FOS; protein c-Fos [KO:K04379]
100411213  ETS1; protein C-ets-1 isoform X6 [KO:K02678]
100400727  MMP1; LOW QUALITY PROTEIN: interstitial collagenase [KO:K01388] [EC:3.4.24.7]
100387448  MMP2; 72 kDa type IV collagenase isoform X1 [KO:K01398] [EC:3.4.24.24]
100415095  MMP9; matrix metalloproteinase-9 [KO:K01403] [EC:3.4.24.35]
100390587  CXCL8; interleukin-8 [KO:K10030]
100408304  CDK4; cyclin-dependent kinase 4 [KO:K02089] [EC:2.7.11.22]
100411926  RPS6KA5; ribosomal protein S6 kinase alpha-5 isoform X1 [KO:K04445] [EC:2.7.11.1]
100403596  RET; proto-oncogene tyrosine-protein kinase receptor Ret isoform X1 [KO:K05126] [EC:2.7.10.1]
100409420  CCDC6; coiled-coil domain-containing protein 6 [KO:K09288]
100389831  NCOA4; nuclear receptor coactivator 4 isoform X3 [KO:K09289]
103789024  NTRK1; LOW QUALITY PROTEIN: high affinity nerve growth factor receptor [KO:K03176] [EC:2.7.10.1]
100412800  TPM3; tropomyosin alpha-3 chain isoform X3 [KO:K09290]
100386874  tropomyosin alpha-3 chain-like isoform X1 [KO:K09290]
100393965  tropomyosin alpha-3 chain-like isoform X1 [KO:K09290]
100415679  TPR; nucleoprotein TPR [KO:K09291]
100415422  TFG; protein TFG isoform X1 [KO:K09292]
100407858  RASSF1; ras association domain-containing protein 1 isoform X1 [KO:K09850]
100415559  RASSF5; ras association domain-containing protein 5 isoform X1 [KO:K08015]
100407296  STK4; serine/threonine-protein kinase 4 isoform X1 [KO:K04411]
100389223  DAPK1; death-associated protein kinase 1 isoform X1 [KO:K08803] [EC:2.7.11.1]
100400671  DAPK2; death-associated protein kinase 2 isoform X2 [KO:K08803] [EC:2.7.11.1]
100392899  DAPK3; death-associated protein kinase 3 [KO:K08803] [EC:2.7.11.1]
100397497  PLCG1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [KO:K01116] [EC:3.1.4.11]
100390347  PLCG2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 [KO:K05859] [EC:3.1.4.11]
100393766  ELK1; ETS domain-containing protein Elk-1 [KO:K04375]
100390180  CALM1; calmodulin-1 [KO:K02183]
100386819  CALM2; calmodulin-2 isoform X2 [KO:K02183]
100406081  CALM3; calmodulin-3 [KO:K02183]
100408289  CALML3; calmodulin-like protein 3 [KO:K02183]
100392199  CALML6; calmodulin-like protein 6 isoform X1 [KO:K02183]
100396690  CALML4; calmodulin-like protein 4 isoform X2 [KO:K02183]
108592443  CALML5; calmodulin-like protein 5 [KO:K02183]
118148021  calmodulin-1-like [KO:K02183]
100397956  CAMK2D; calcium/calmodulin-dependent protein kinase type II subunit delta isoform X9 [KO:K04515] [EC:2.7.11.17]
100405903  CAMK2G; calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X1 [KO:K04515] [EC:2.7.11.17]
100391424  calcium/calmodulin-dependent protein kinase type II subunit delta-like [KO:K04515] [EC:2.7.11.17]
100390938  CAMK2A; calcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1 [KO:K04515] [EC:2.7.11.17]
100410352  CAMK2B; calcium/calmodulin-dependent protein kinase type II subunit beta isoform X4 [KO:K04515] [EC:2.7.11.17]
100409316  RALGDS; ral guanine nucleotide dissociation stimulator isoform X2 [KO:K08732]
100398374  RALA; ras-related protein Ral-A [KO:K07834]
100409022  RALB; ras-related protein Ral-B [KO:K07835]
100390070  RALBP1; ralA-binding protein 1 [KO:K08773]
100404291  CDC42; cell division control protein 42 homolog isoform X1 [KO:K04393]
100404109  RAC1; ras-related C3 botulinum toxin substrate 1 isoform X1 [KO:K04392]
100895294  LOW QUALITY PROTEIN: ras-related C3 botulinum toxin substrate 1-like [KO:K04392]
100395636  RAC2; ras-related C3 botulinum toxin substrate 2 [KO:K07860]
100400756  RAC3; ras-related C3 botulinum toxin substrate 3 isoform X1 [KO:K07861]
100397093  PLD1; phospholipase D1 isoform X1 [KO:K01115] [EC:3.1.4.4]
100391217  PLD2; phospholipase D2 isoform X1 [KO:K01115] [EC:3.1.4.4]
100392721  MAPK8; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
100387686  MAPK9; mitogen-activated protein kinase 9 isoform X1 [KO:K04440] [EC:2.7.11.24]
100390109  MAPK10; mitogen-activated protein kinase 10 isoform X7 [KO:K04440] [EC:2.7.11.24]
100386350  PAX8; paired box protein Pax-8 isoform X1 [KO:K09293]
100414099  PPARG; peroxisome proliferator-activated receptor gamma isoform X1 [KO:K08530]
100407498  RXRA; retinoic acid receptor RXR-alpha isoform X1 [KO:K08524]
100414004  RXRB; retinoic acid receptor RXR-beta isoform X2 [KO:K08525]
100386851  RXRG; retinoic acid receptor RXR-gamma isoform X1 [KO:K08526]
100396363  RARB; retinoic acid receptor beta isoform X2 [KO:K08528]
100385918  ESR1; estrogen receptor isoform X1 [KO:K08550]
100415266  ESR2; estrogen receptor beta [KO:K08551]
100385756  NCOA1; nuclear receptor coactivator 1 isoform X2 [KO:K09101] [EC:2.3.1.48]
100392051  NCOA3; nuclear receptor coactivator 3 isoform X7 [KO:K11256] [EC:2.3.1.48]
100407824  SP1; transcription factor Sp1 isoform X3 [KO:K04684]
100399649  PPARD; peroxisome proliferator-activated receptor delta isoform X1 [KO:K04504]
100415000  JUP; junction plakoglobin [KO:K10056]
100402990  ZBTB16; zinc finger and BTB domain-containing protein 16 [KO:K10055]
100410811  RARA; retinoic acid receptor alpha isoform X2 [KO:K08527]
100388293  CCNA2; cyclin-A2 [KO:K06627]
100393051  CCNA1; cyclin-A1 isoform X2 [KO:K06627]
100388843  PML; protein PML isoform X1 [KO:K10054] [EC:2.3.2.-]
100385071  RUNX1; runt-related transcription factor 1 isoform X1 [KO:K08367]
100409447  RUNX1T1; LOW QUALITY PROTEIN: protein CBFA2T1 [KO:K10053]
100391618  SPI1; transcription factor PU.1 isoform X1 [KO:K09438]
103796367  CEBPA; CCAAT/enhancer-binding protein alpha [KO:K09055]
100413917  CSF2RA; granulocyte-macrophage colony-stimulating factor receptor subunit alpha isoform X1 [KO:K05066]
100393434  CSF3R; granulocyte colony-stimulating factor receptor isoform X1 [KO:K05061]
100406047  CSF1R; macrophage colony-stimulating factor 1 receptor isoform X1 [KO:K05090] [EC:2.7.10.1]
100394189  CDKN2A; cyclin-dependent kinase inhibitor 2A isoform X1 [KO:K06621]
100414261  E2F1; transcription factor E2F1 [KO:K17454]
100414776  E2F2; transcription factor E2F2 [KO:K09389]
100390235  E2F3; transcription factor E2F3 isoform X4 [KO:K06620]
100389089  MAX; protein max isoform X1 [KO:K04453]
103793292  protein max-like [KO:K04453]
100398482  ZBTB17; zinc finger and BTB domain-containing protein 17 isoform X1 [KO:K10500]
100392363  CDKN2B; cyclin-dependent kinase 4 inhibitor B [KO:K04685]
100385604  CDK6; cyclin-dependent kinase 6 isoform X1 [KO:K02091] [EC:2.7.11.22]
100390172  CCND2; G1/S-specific cyclin-D2 [KO:K10151]
100408249  CCND3; G1/S-specific cyclin-D3 isoform X1 [KO:K10152]
100404584  CKS2; cyclin-dependent kinases regulatory subunit 2 [KO:K02219]
100391541  CKS1B; cyclin-dependent kinases regulatory subunit 1 [KO:K02219]
100388830  cyclin-dependent kinases regulatory subunit 1-like [KO:K02219]
103794276  cyclin-dependent kinases regulatory subunit 2-like [KO:K02219]
108591819  cyclin-dependent kinases regulatory subunit 1-like [KO:K02219]
108592940  cyclin-dependent kinases regulatory subunit 1-like [KO:K02219]
100398187  SKP1; S-phase kinase-associated protein 1 [KO:K03094]
100414523  S-phase kinase-associated protein 1-like [KO:K03094]
100395702  CUL1; cullin-1 [KO:K03347]
100391523  RBX1; E3 ubiquitin-protein ligase RBX1 [KO:K03868] [EC:2.3.2.32]
103796394  E3 ubiquitin-protein ligase RBX1-like [KO:K03868] [EC:2.3.2.32]
100393248  SKP2; S-phase kinase-associated protein 2 isoform X2 [KO:K03875]
100398703  CDK2; cyclin-dependent kinase 2 [KO:K02206] [EC:2.7.11.22]
100396520  CCNE1; G1/S-specific cyclin-E1 isoform X1 [KO:K06626]
100403750  CCNE2; G1/S-specific cyclin-E2 isoform X1 [KO:K06626]
100397928  RB1; retinoblastoma-associated protein isoform X1 [KO:K06618]
100412572  GADD45B; growth arrest and DNA damage-inducible protein GADD45 beta [KO:K04402]
100405303  GADD45G; growth arrest and DNA damage-inducible protein GADD45 gamma [KO:K04402]
100394399  GADD45A; growth arrest and DNA damage-inducible protein GADD45 alpha isoform X1 [KO:K04402]
100391322  BAX; apoptosis regulator BAX isoform X1 [KO:K02159]
100387945  BAK1; bcl-2 homologous antagonist/killer [KO:K14021]
100390419  DDB2; DNA damage-binding protein 2 isoform X1 [KO:K10140]
100403269  POLK; DNA polymerase kappa isoform X1 [KO:K03511] [EC:2.7.7.7]
100894730  TERT; telomerase reverse transcriptase isoform X1 [KO:K11126] [EC:2.7.7.49]
100403631  TERC; telomerase RNA component [KO:K22183]
100393363  MITF; microphthalmia-associated transcription factor isoform X3 [KO:K09455]
100401979  TGFB1; transforming growth factor beta-1 proprotein isoform X2 [KO:K13375]
100390586  TGFB2; transforming growth factor beta-2 proprotein isoform X2 [KO:K13376]
100392463  TGFB3; transforming growth factor beta-3 proprotein isoform X1 [KO:K13377]
100389596  TGFBR1; TGF-beta receptor type-1 isoform X2 [KO:K04674] [EC:2.7.11.30]
100404359  TGFBR2; TGF-beta receptor type-2 isoform X1 [KO:K04388] [EC:2.7.11.30]
100396826  SMAD2; mothers against decapentaplegic homolog 2 isoform X1 [KO:K04500]
100393808  SMAD3; mothers against decapentaplegic homolog 3 isoform X2 [KO:K23605]
100409302  SMAD4; mothers against decapentaplegic homolog 4 isoform X1 [KO:K04501]
100403987  MECOM; histone-lysine N-methyltransferase MECOM isoform X2 [KO:K04462] [EC:2.1.1.367]
100402402  CTBP2; C-terminal-binding protein 2 isoform X4 [KO:K04496] [EC:1.1.1.428]
100412920  CTBP1; C-terminal-binding protein 1 isoform X1 [KO:K04496] [EC:1.1.1.428]
100398309  C-terminal-binding protein 2 [KO:K04496] [EC:1.1.1.428]
100402327  HDAC2; LOW QUALITY PROTEIN: histone deacetylase 2 [KO:K06067] [EC:3.5.1.98]
100399690  HDAC1; histone deacetylase 1 isoform X2 [KO:K06067] [EC:3.5.1.98]
100401228  LOW QUALITY PROTEIN: histone deacetylase 1-like [KO:K06067] [EC:3.5.1.98]
100406787  MLH1; DNA mismatch repair protein Mlh1 isoform X2 [KO:K08734]
100394665  MSH2; DNA mismatch repair protein Msh2 [KO:K08735]
100406902  MSH3; DNA mismatch repair protein Msh3 isoform X1 [KO:K08736]
100386465  MSH6; LOW QUALITY PROTEIN: DNA mismatch repair protein Msh6 [KO:K08737]
100397509  BRCA2; breast cancer type 2 susceptibility protein isoform X3 [KO:K08775]
100411922  RAD51; DNA repair protein RAD51 homolog 1 isoform X1 [KO:K04482]
100404850  FASLG; tumor necrosis factor ligand superfamily member 6 [KO:K04389]
100397803  FAS; tumor necrosis factor receptor superfamily member 6 precursor [KO:K04390]
100410616  FADD; FAS-associated death domain protein [KO:K02373]
100395220  CASP8; caspase-8 isoform X1 [KO:K04398] [EC:3.4.22.61]
100403496  BID; BH3-interacting domain death agonist isoform X2 [KO:K04726]
100404690  PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1 [KO:K10131]
100387604  BBC3; LOW QUALITY PROTEIN: bcl-2-binding component 3 [KO:K10132]
100399968  BCL2L11; bcl-2-like protein 11 isoform X16 [KO:K16341]
108593648  cytochrome c-like [KO:K08738]
108593819  cytochrome c-like [KO:K08738]
108593835  cytochrome c-like [KO:K08738]
108588095  cytochrome c-like [KO:K08738]
100406761  cytochrome c-like [KO:K08738]
100401718  cytochrome c [KO:K08738]
100413276  cytochrome c-like [KO:K08738]
108591937  cytochrome c-like [KO:K08738]
108592162  cytochrome c-like [KO:K08738]
108591932  cytochrome c, somatic-like [KO:K08738]
100403825  APAF1; apoptotic protease-activating factor 1 isoform X1 [KO:K02084]
100386577  CASP7; caspase-7 [KO:K04397] [EC:3.4.22.60]
100409712  KEAP1; kelch-like ECH-associated protein 1 [KO:K10456]
100386539  NFE2L2; nuclear factor erythroid 2-related factor 2 isoform X1 [KO:K05638]
100414343  HMOX1; heme oxygenase 1 [KO:K00510] [EC:1.14.14.18]
100405090  NQO1; NAD(P)H dehydrogenase [quinone] 1 isoform X1 [KO:K00355] [EC:1.6.5.2]
100391062  MGST2; microsomal glutathione S-transferase 2 isoform X1 [KO:K00799] [EC:2.5.1.18]
100387311  glutathione S-transferase theta-1 isoform X1 [KO:K00799] [EC:2.5.1.18]
100389598  glutathione S-transferase theta-4 [KO:K00799] [EC:2.5.1.18]
100400212  GSTO2; glutathione S-transferase omega-2 isoform X3 [KO:K00799] [EC:2.5.1.18]
100399847  GSTO1; glutathione S-transferase omega-1 isoform X1 [KO:K00799] [EC:2.5.1.18]
100386143  MGST3; microsomal glutathione S-transferase 3 isoform X2 [KO:K00799] [EC:2.5.1.18]
100386984  glutathione S-transferase A1 [KO:K00799] [EC:2.5.1.18]
100400731  glutathione S-transferase A3 isoform X1 [KO:K00799] [EC:2.5.1.18]
100401098  glutathione S-transferase alpha-4-like isoform X4 [KO:K00799] [EC:2.5.1.18]
100401476  GSTA4; glutathione S-transferase A4 [KO:K00799] [EC:2.5.1.18]
100392584  MGST1; microsomal glutathione S-transferase 1 isoform X1 [KO:K00799] [EC:2.5.1.18]
100406483  glutathione S-transferase Mu 5 [KO:K00799] [EC:2.5.1.18]
100385358  glutathione S-transferase Mu 2 [KO:K00799] [EC:2.5.1.18]
100407094  glutathione S-transferase Mu 1 isoform X1 [KO:K00799] [EC:2.5.1.18]
100407453  GSTM3; glutathione S-transferase Mu 3 [KO:K00799] [EC:2.5.1.18]
100388510  glutathione S-transferase theta-4 isoform X1 [KO:K00799] [EC:2.5.1.18]
100393909  glutathione S-transferase Mu 5-like [KO:K00799] [EC:2.5.1.18]
100411587  glutathione S-transferase Mu 5-like [KO:K00799] [EC:2.5.1.18]
100895885  glutathione S-transferase Mu 5-like [KO:K00799] [EC:2.5.1.18]
118146251  glutathione S-transferase theta-4-like isoform X1 [KO:K00799] [EC:2.5.1.18]
128928073  glutathione S-transferase theta-1-like isoform X1 [KO:K00799] [EC:2.5.1.18]
100398632  GSTP1; glutathione S-transferase P isoform X1 [KO:K23790] [EC:2.5.1.18]
100401029  TXNRD1; thioredoxin reductase 1, cytoplasmic [KO:K22182] [EC:1.8.1.9]
100388762  TXNRD3; thioredoxin reductase 3 isoform X1 [KO:K22182] [EC:1.8.1.9]
100413738  TXNRD2; thioredoxin reductase 2, mitochondrial isoform X5 [KO:K22182] [EC:1.8.1.9]
103788323  VHL; von Hippel-Lindau disease tumor suppressor isoform X1 [KO:K03871]
100404481  ELOC; elongin-C isoform X1 [KO:K03872]
118144202  elongin-C-like [KO:K03872]
118155232  elongin-C-like [KO:K03872]
100396815  ELOB; elongin-B [KO:K03873]
100411096  elongin-B-like [KO:K03873]
100395340  CUL2; cullin-2 [KO:K03870]
100389821  EGLN3; prolyl hydroxylase EGLN3 isoform X1 [KO:K09592] [EC:1.14.11.29]
100413526  EGLN1; egl nine homolog 1 isoform X1 [KO:K09592] [EC:1.14.11.29]
100397980  EGLN2; prolyl hydroxylase EGLN2 isoform X1 [KO:K09592] [EC:1.14.11.29]
100404499  FH; fumarate hydratase, mitochondrial isoform X1 [KO:K01679] [EC:4.2.1.2]
100402453  LOW QUALITY PROTEIN: fumarate hydratase, mitochondrial-like [KO:K01679] [EC:4.2.1.2]
100411678  HIF1A; hypoxia-inducible factor 1-alpha isoform X1 [KO:K08268]
100396711  EPAS1; endothelial PAS domain-containing protein 1 isoform X1 [KO:K09095]
100410534  ARNT; aryl hydrocarbon receptor nuclear translocator isoform X3 [KO:K09097]
100407922  ARNT2; aryl hydrocarbon receptor nuclear translocator 2 isoform X3 [KO:K15589]
100395278  EP300; histone acetyltransferase p300 [KO:K04498] [EC:2.3.1.48]
100405037  CREBBP; CREB-binding protein isoform X1 [KO:K04498] [EC:2.3.1.48]
100404544  SLC2A1; solute carrier family 2, facilitated glucose transporter member 1 [KO:K07299]
100414977  JAG1; protein jagged-1 isoform X1 [KO:K06052]
100407348  JAG2; protein jagged-2 [KO:K21635]
100408189  DLL4; delta-like protein 4 [KO:K06051]
100403776  DLL1; delta-like protein 1 [KO:K06051]
100398335  DLL3; delta-like protein 3 isoform X2 [KO:K06051]
103795708  NOTCH1; neurogenic locus notch homolog protein 1 isoform X1 [KO:K02599]
100393852  NOTCH2; neurogenic locus notch homolog protein 2 isoform X1 [KO:K20994]
100408994  NOTCH3; neurogenic locus notch homolog protein 3 isoform X1 [KO:K20995]
108587674  NOTCH4; neurogenic locus notch homolog protein 4 isoform X4 [KO:K20996]
100398058  HES1; transcription factor HES-1 [KO:K06054]
100397404  HES5; transcription factor HES-5 [KO:K06055]
100389602  HEY1; hairy/enhancer-of-split related with YRPW motif protein 1 isoform X2 [KO:K09091]
100395441  HEY2; hairy/enhancer-of-split related with YRPW motif protein 2 isoform X1 [KO:K09091]
100399453  HEYL; hairy/enhancer-of-split related with YRPW motif-like protein isoform X1 [KO:K09091]
100388404  FLT4; LOW QUALITY PROTEIN: vascular endothelial growth factor receptor 3 [KO:K05097] [EC:2.7.10.1]
100395600  SHH; sonic hedgehog protein [KO:K11988]
100410387  PTCH1; protein patched homolog 1 isoform X1 [KO:K06225]
100394403  SMO; smoothened homolog isoform X1 [KO:K06226]
100407677  KIF7; kinesin-like protein KIF7 isoform X3 [KO:K18806]
100398505  SUFU; suppressor of fused homolog isoform X1 [KO:K06229]
100401526  GLI1; zinc finger protein GLI1 isoform X1 [KO:K16797]
100413916  GLI2; zinc finger protein GLI2 isoform X1 [KO:K16798]
118149682  LOW QUALITY PROTEIN: zinc finger protein GLI2-like [KO:K16798]
100400779  GLI3; transcriptional activator GLI3 isoform X1 [KO:K06230]
100408260  BMP2; bone morphogenetic protein 2 [KO:K21283]
100398270  BMP4; bone morphogenetic protein 4 isoform X1 [KO:K04662]
100404963  HHIP; hedgehog-interacting protein isoform X1 [KO:K06231]
100394151  PTCH2; protein patched homolog 2 isoform X3 [KO:K11101]
100401612  AR; androgen receptor isoform X1 [KO:K08557]
100409130  HSP90AB1; heat shock protein HSP 90-beta [KO:K04079]
100409403  LOW QUALITY PROTEIN: heat shock protein HSP 90-beta-like [KO:K04079]
100411012  HSP90AA1; heat shock protein HSP 90-alpha [KO:K04079]
100392924  heat shock protein HSP 90-beta-like [KO:K04079]
100403265  LOW QUALITY PROTEIN: heat shock protein HSP 90-beta-like [KO:K04079]
100397163  HSP90B1; endoplasmin [KO:K09487]
Compound
C00027  Hydrogen peroxide
C00039  DNA
C00076  Calcium cation
C00122  Fumarate
C00149  (S)-Malate
C00165  Diacylglycerol
C00187  Cholesterol
C00280  Androstenedione
C00410  Progesterone
C00416  Phosphatidate
C00533  Nitric oxide
C00535  Testosterone
C00575  3',5'-Cyclic AMP
C00584  Prostaglandin E2
C00681  1-Acyl-sn-glycerol 3-phosphate
C00704  Superoxide
C00735  Cortisol
C00762  Cortisone
C00777  Retinoate
C00951  Estradiol-17beta
C01227  Dehydroepiandrosterone
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01471  Acrolein
C03917  Dihydrotestosterone
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C07653  Flutamide
C15493  9-cis-Retinoic acid
C16038  2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
C16844  Hydroxyl radical
C21641  Hydroperoxyl radical
C21642  4-Hydroxynonenal
Reference
  Authors
Weinberg RA.
  Title
The biology of cancer
  Journal
Garland Science, Taylor & Francis Group, LLC (2007)
Reference
PMID:10647931
  Authors
Hanahan D, Weinberg RA
  Title
The hallmarks of cancer.
  Journal
Cell 100:57-70 (2000)
DOI:10.1016/S0092-8674(00)81683-9
Reference
PMID:15000146
  Authors
Grady WM.
  Title
Genomic instability and colon cancer.
  Journal
Cancer Metastasis Rev 23:11-27 (2004)
DOI:10.1023/A:1025861527711
Reference
PMID:16555243
  Authors
Soreide K, Janssen EA, Soiland H, Korner H, Baak JP.
  Title
Microsatellite instability in colorectal cancer.
  Journal
Br J Surg 93:395-406 (2006)
DOI:10.1002/bjs.5328
Reference
PMID:11078609
  Authors
Anwar S, Hall C, White J, Deakin M, Farrell W, Elder JB.
  Title
Hereditary non-polyposis colorectal cancer: an updated review.
  Journal
Eur J Surg Oncol 26:635-45 (2000)
DOI:10.1053/ejso.2000.0974
Reference
PMID:16699851
  Authors
Takayama T, Miyanishi K, Hayashi T, Sato Y, Niitsu Y.
  Title
Colorectal cancer: genetics of development and metastasis.
  Journal
J Gastroenterol 41:185-92 (2006)
DOI:10.1007/s00535-006-1801-6
Reference
PMID:12621137
  Authors
Lynch HT, de la Chapelle A.
  Title
Hereditary colorectal cancer.
  Journal
N Engl J Med 348:919-32 (2003)
DOI:10.1056/NEJMra012242
Reference
PMID:12951588
  Authors
Rajagopalan H, Nowak MA, Vogelstein B, Lengauer C.
  Title
The significance of unstable chromosomes in colorectal cancer.
  Journal
Nat Rev Cancer 3:695-701 (2003)
DOI:10.1038/nrc1165
Reference
PMID:10505543
  Authors
Behrens J.
  Title
Cadherins and catenins: role in signal transduction and tumor progression.
  Journal
Cancer Metastasis Rev 18:15-30 (1999)
DOI:10.1023/A:1006200102166
Reference
PMID:16042571
  Authors
Behrens J.
  Title
The role of the Wnt signalling pathway in colorectal tumorigenesis.
  Journal
Biochem Soc Trans 33:672-5 (2005)
DOI:10.1042/BST0330672
Reference
PMID:15349822
  Authors
Behrens J, Lustig B.
  Title
The Wnt connection to tumorigenesis.
  Journal
Int J Dev Biol 48:477-87 (2004)
DOI:10.1387/ijdb.041815jb
Reference
PMID:9196022
  Authors
Polakis P.
  Title
The adenomatous polyposis coli (APC) tumor suppressor.
  Journal
Biochim Biophys Acta 1332:F127-47 (1997)
DOI:10.1016/S0304-419X(97)00008-5
Reference
PMID:12737309
  Authors
Janssen KP.
  Title
Murine models of colorectal cancer: studying the role of oncogenic K-ras.
  Journal
Cell Mol Life Sci 60:495-506 (2003)
DOI:10.1007/s000180300041
Reference
PMID:11459867
  Authors
Adjei AA.
  Title
Blocking oncogenic Ras signaling for cancer therapy.
  Journal
J Natl Cancer Inst 93:1062-74 (2001)
DOI:10.1093/jnci/93.14.1062
Reference
PMID:15573119
  Authors
Arakawa H.
  Title
Netrin-1 and its receptors in tumorigenesis.
  Journal
Nat Rev Cancer 4:978-87 (2004)
DOI:10.1038/nrc1504
Reference
PMID:15310786
  Authors
Mehlen P, Fearon ER.
  Title
Role of the dependence receptor DCC in colorectal cancer pathogenesis.
  Journal
J Clin Oncol 22:3420-8 (2004)
DOI:10.1200/JCO.2004.02.019
Reference
PMID:11223406
  Authors
Peltomaki P.
  Title
DNA mismatch repair and cancer.
  Journal
Mutat Res 488:77-85 (2001)
DOI:10.1016/S1383-5742(00)00058-2
Reference
PMID:15711891
  Authors
Li F, Cao Y, Townsend CM Jr, Ko TC.
  Title
TGF-beta signaling in colon cancer cells.
  Journal
World J Surg 29:306-11 (2005)
DOI:10.1007/s00268-004-7813-6
Reference
PMID:11170304
  Authors
Roman C, Saha D, Beauchamp R.
  Title
TGF-beta and colorectal carcinogenesis.
  Journal
Microsc Res Tech 52:450-7 (2001)
DOI:10.1002/1097-0029(20010215)52:4<450::AID-JEMT1030>3.0.CO;2-O
Reference
PMID:16326109
  Authors
Watson AJ.
  Title
An overview of apoptosis and the prevention of colorectal cancer.
  Journal
Crit Rev Oncol Hematol 57:107-21 (2006)
DOI:10.1016/j.critrevonc.2005.06.005
Reference
PMID:15479695
  Authors
Watson AJ.
  Title
Apoptosis and colorectal cancer.
  Journal
Gut 53:1701-9 (2004)
DOI:10.1136/gut.2004.052704
Reference
PMID:11477132
  Authors
Houlston RS.
  Title
What we could do now: molecular pathology of colorectal cancer.
  Journal
Mol Pathol 54:206-14 (2001)
DOI:10.1136/mp.54.4.206
Reference
  Authors
Von Hoff D, Evans D, Hruban R (ed).
  Title
Pancreatic cancer
  Journal
Jones and Bartlett publishers (2005)
Reference
  Authors
Niitsu Y, Yokota J (ed).
  Title
[Oncogenes and Tumor Suppressor Genes for Medical Oncologist] (In Japanese)
  Journal
Nankodo (1999)
Reference
PMID:12459728
  Authors
Bardeesy N, DePinho RA.
  Title
Pancreatic cancer biology and genetics.
  Journal
Nat Rev Cancer 2:897-909 (2002)
DOI:10.1038/nrc949
Reference
PMID:11407945
  Authors
Bardeesy N, Sharpless NE, DePinho RA, Merlino G.
  Title
The genetics of pancreatic adenocarcinoma: a roadmap for a mouse model.
  Journal
Semin Cancer Biol 11:201-18 (2001)
DOI:10.1006/scbi.2000.0371
Reference
PMID:12946833
  Authors
Cowgill SM, Muscarella P.
  Title
The genetics of pancreatic cancer.
  Journal
Am J Surg 186:279-86 (2003)
DOI:10.1016/S0002-9610(03)00226-5
Reference
PMID:16702400
  Authors
Hezel AF, Kimmelman AC, Stanger BZ, Bardeesy N, Depinho RA.
  Title
Genetics and biology of pancreatic ductal adenocarcinoma.
  Journal
Genes Dev 20:1218-49 (2006)
DOI:10.1101/gad.1415606
Reference
PMID:10740269
  Authors
Shields JM, Pruitt K, McFall A, Shaub A, Der CJ.
  Title
Understanding Ras: 'it ain't over 'til it's over'.
  Journal
Trends Cell Biol 10:147-54 (2000)
DOI:10.1016/S0962-8924(00)01740-2
Reference
PMID:12648469
  Authors
Holbro T, Civenni G, Hynes NE.
  Title
The ErbB receptors and their role in cancer progression.
  Journal
Exp Cell Res 284:99-110 (2003)
DOI:10.1016/S0014-4827(02)00099-X
Reference
PMID:14967450
  Authors
Marmor MD, Skaria KB, Yarden Y.
  Title
Signal transduction and oncogenesis by ErbB/HER receptors.
  Journal
Int J Radiat Oncol Biol Phys 58:903-13 (2004)
DOI:10.1016/j.ijrobp.2003.06.002
Reference
PMID:14586404
  Authors
DeArmond D, Brattain MG, Jessup JM, Kreisberg J, Malik S, Zhao S, Freeman JW.
  Title
Autocrine-mediated ErbB-2 kinase activation of STAT3 is required for growth factor independence of pancreatic cancer cell lines.
  Journal
Oncogene 22:7781-95 (2003)
DOI:10.1038/sj.onc.1206966
Reference
PMID:12545153
  Authors
Wei D, Le X, Zheng L, Wang L, Frey JA, Gao AC, Peng Z, Huang S, Xiong HQ, Abbruzzese JL, Xie K.
  Title
Stat3 activation regulates the expression of vascular endothelial growth factor and human pancreatic cancer angiogenesis and metastasis.
  Journal
Oncogene 22:319-29 (2003)
DOI:10.1038/sj.onc.1206122
Reference
PMID:14580692
  Authors
Toyonaga T, Nakano K, Nagano M, Zhao G, Yamaguchi K, Kuroki S, Eguchi T, Chijiiwa K, Tsuneyoshi M, Tanaka M.
  Title
Blockade of constitutively activated Janus kinase/signal transducer and activator of transcription-3 pathway inhibits growth of human pancreatic cancer.
  Journal
Cancer Lett 201:107-16 (2003)
DOI:10.1016/S0304-3835(03)00482-8
Reference
PMID:12079267
  Authors
Schmid RM.
  Title
Genetic basis of pancreatic cancer.
  Journal
Best Pract Res Clin Gastroenterol 16:421-33 (2002)
DOI:10.1053/bega.2002.0316
Reference
PMID:15774796
  Authors
Elliott RL, Blobe GC.
  Title
Role of transforming growth factor Beta in human cancer.
  Journal
J Clin Oncol 23:2078-93 (2005)
DOI:10.1200/JCO.2005.02.047
Reference
PMID:15823750
  Authors
Rudkin TM, Foulkes WD.
  Title
BRCA2: breaks, mistakes and failed separations.
  Journal
Trends Mol Med 11:145-8 (2005)
DOI:10.1016/j.molmed.2005.02.003
Reference
PMID:11707511
  Authors
Venkitaraman AR.
  Title
Functions of BRCA1 and BRCA2 in the biological response to DNA damage.
  Journal
J Cell Sci 114:3591-8 (2001)
Reference
PMID:15639402
  Authors
Soni D, King JA, Kaye AH, Hovens CM.
  Title
Genetics of glioblastoma multiforme: mitogenic signaling and cell cycle pathways converge.
  Journal
J Clin Neurosci 12:1-5 (2005)
DOI:10.1016/j.jocn.2004.04.001
Reference
PMID:12154354
  Authors
Zhu Y, Parada LF.
  Title
The molecular and genetic basis of neurological tumours.
  Journal
Nat Rev Cancer 2:616-26 (2002)
DOI:10.1038/nrc866
Reference
PMID:11253051
  Authors
Holland EC.
  Title
Gliomagenesis: genetic alterations and mouse models.
  Journal
Nat Rev Genet 2:120-9 (2001)
DOI:10.1038/35052535
Reference
PMID:16700615
  Authors
Bansal K, Liang ML, Rutka JT.
  Title
Molecular biology of human gliomas.
  Journal
Technol Cancer Res Treat 5:185-94 (2006)
DOI:10.1177/153303460600500302
Reference
  Authors
Tabuchi K (ed).
  Title
[Gliomas: Research and therapy] (In Japanese)
  Journal
Springer-Verlag Tokyo (2006)
Reference
PMID:12762887
  Authors
Kapoor GS, O'Rourke DM.
  Title
Mitogenic signaling cascades in glial tumors.
  Journal
Neurosurgery 52:1425-34; discussion 1434-5 (2003)
DOI:10.1227/01.NEU.0000065135.28143.39
Reference
PMID:16095998
  Authors
Hulleman E, Helin K.
  Title
Molecular mechanisms in gliomagenesis.
  Journal
Adv Cancer Res 94:1-27 (2005)
DOI:10.1016/S0065-230X(05)94001-3
Reference
PMID:11057895
  Authors
Schlessinger J.
  Title
Cell signaling by receptor tyrosine kinases.
  Journal
Cell 103:211-25 (2000)
DOI:10.1016/S0092-8674(00)00114-8
Reference
PMID:9643506
  Authors
Ng HK, Lam PY.
  Title
The molecular genetics of central nervous system tumors.
  Journal
Pathology 30:196-202 (1998)
DOI:10.1080/00313029800169236
Reference
PMID:12084351
  Authors
Knobbe CB, Merlo A, Reifenberger G.
  Title
Pten signaling in gliomas.
  Journal
Neuro-oncol 4:196-211 (2002)
DOI:10.1093/neuonc/4.3.196
Reference
PMID:16557281
  Authors
Kondo T, Ezzat S, Asa SL.
  Title
Pathogenetic mechanisms in thyroid follicular-cell neoplasia.
  Journal
Nat Rev Cancer 6:292-306 (2006)
DOI:10.1038/nrc1836
Reference
PMID:16551846
  Authors
Chiloeches A, Marais R.
  Title
Is BRAF the Achilles' Heel of thyroid cancer?
  Journal
Clin Cancer Res 12:1661-4 (2006)
DOI:10.1158/1078-0432.CCR-06-0051
Reference
PMID:16946003
  Authors
Reddi HV, McIver B, Grebe SK, Eberhardt NL
  Title
The paired box-8/peroxisome proliferator-activated receptor-gamma oncogene in thyroid tumorigenesis.
  Journal
Endocrinology 148:932-5 (2007)
DOI:10.1210/en.2006-0926
Reference
PMID:17062879
  Authors
Santoro M, Melillo RM, Fusco A.
  Title
RET/PTC activation in papillary thyroid carcinoma: European Journal of Endocrinology Prize Lecture.
  Journal
Eur J Endocrinol 155:645-653 (2006)
DOI:10.1530/eje.1.02289
Reference
PMID:16242838
  Authors
Pierotti MA, Greco A.
  Title
Oncogenic rearrangements of the NTRK1/NGF receptor.
  Journal
Cancer Lett 232:90-8 (2006)
DOI:10.1016/j.canlet.2005.07.043
Reference
PMID:16189702
  Authors
Sobrinho-Simoes M, Preto A, Rocha AS, Castro P, Maximo V, Fonseca E, Soares P.
  Title
Molecular pathology of well-differentiated thyroid carcinomas.
  Journal
Virchows Arch 447:787-93 (2005)
DOI:10.1007/s00428-005-0065-5
Reference
PMID:11165748
  Authors
Gimm O.
  Title
Thyroid cancer.
  Journal
Cancer Lett 163:143-56 (2001)
DOI:10.1016/S0304-3835(00)00697-2
Reference
PMID:12094241
  Authors
Williams D.
  Title
Cancer after nuclear fallout: lessons from the Chernobyl accident.
  Journal
Nat Rev Cancer 2:543-9 (2002)
DOI:10.1038/nrc845
Reference
PMID:16236521
  Authors
Steffen B, Muller-Tidow C, Schwable J, Berdel WE, Serve H.
  Title
The molecular pathogenesis of acute myeloid leukemia.
  Journal
Crit Rev Oncol Hematol 56:195-221 (2005)
DOI:10.1016/j.critrevonc.2004.10.012
Reference
PMID:12563308
  Authors
Tenen DG.
  Title
Disruption of differentiation in human cancer: AML shows the way.
  Journal
Nat Rev Cancer 3:89-101 (2003)
DOI:10.1038/nrc989
Reference
PMID:16146838
  Authors
Choudhary C, Muller-Tidow C, Berdel WE, Serve H.
  Title
Signal transduction of oncogenic Flt3.
  Journal
Int J Hematol 82:93-9 (2005)
DOI:10.1532/IJH97.05090
Reference
PMID:12951584
  Authors
Stirewalt DL, Radich JP.
  Title
The role of FLT3 in haematopoietic malignancies.
  Journal
Nat Rev Cancer 3:650-65 (2003)
DOI:10.1038/nrc1169
Reference
PMID:16642045
  Authors
Martelli AM, Nyakern M, Tabellini G, Bortul R, Tazzari PL, Evangelisti C, Cocco L.
  Title
Phosphoinositide 3-kinase/Akt signaling pathway and its therapeutical implications for human acute myeloid leukemia.
  Journal
Leukemia 20:911-28 (2006)
DOI:10.1038/sj.leu.2404245
Reference
PMID:15625120
  Authors
Lennartsson J, Jelacic T, Linnekin D, Shivakrupa R.
  Title
Normal and oncogenic forms of the receptor tyrosine kinase kit.
  Journal
Stem Cells 23:16-43 (2005)
DOI:10.1634/stemcells.2004-0117
Reference
PMID:11721960
  Authors
Lorsbach RB, Downing JR.
  Title
The role of the AML1 transcription factor in leukemogenesis.
  Journal
Int J Hematol 74:258-65 (2001)
DOI:10.1007/BF02982058
Reference
PMID:12468433
  Authors
Mizuki M, Schwable J, Steur C, Choudhary C, Agrawal S, Sargin B, Steffen B, Matsumura I, Kanakura Y, Bohmer FD, Muller-Tidow C, Berdel WE, Serve H.
  Title
Suppression of myeloid transcription factors and induction of STAT response genes by AML-specific Flt3 mutations.
  Journal
Blood 101:3164-73 (2003)
DOI:10.1182/blood-2002-06-1677
Reference
PMID:17554387
  Authors
Mikesch JH, Steffen B, Berdel WE, Serve H, Muller-Tidow C.
  Title
The emerging role of Wnt signaling in the pathogenesis of acute myeloid leukemia.
  Journal
Leukemia 21:1638-47 (2007)
DOI:10.1038/sj.leu.2404732
Reference
PMID:16352814
  Authors
Mueller BU, Pabst T, Fos J, Petkovic V, Fey MF, Asou N, Buergi U, Tenen DG.
  Title
ATRA resolves the differentiation block in t(15;17) acute myeloid leukemia by restoring PU.1 expression.
  Journal
Blood 107:3330-8 (2006)
DOI:10.1182/blood-2005-07-3068
Reference
PMID:15719031
  Authors
Ren R.
  Title
Mechanisms of BCR-ABL in the pathogenesis of chronic myelogenous leukaemia.
  Journal
Nat Rev Cancer 5:172-83 (2005)
DOI:10.1038/nrc1567
Reference
PMID:11071626
  Authors
Deininger MW, Goldman JM, Melo JV.
  Title
The molecular biology of chronic myeloid leukemia.
  Journal
Blood 96:3343-56 (2000)
Reference
PMID:14982876
  Authors
Calabretta B, Perrotti D.
  Title
The biology of CML blast crisis.
  Journal
Blood 103:4010-22 (2004)
DOI:10.1182/blood-2003-12-4111
Reference
PMID:10403855
  Authors
Faderl S, Talpaz M, Estrov Z, O'Brien S, Kurzrock R, Kantarjian HM.
  Title
The biology of chronic myeloid leukemia.
  Journal
N Engl J Med 341:164-72 (1999)
DOI:10.1056/NEJM199907153410306
Reference
PMID:15156182
  Authors
Mitani K.
  Title
Molecular mechanisms of leukemogenesis by AML1/EVI-1.
  Journal
Oncogene 23:4263-9 (2004)
DOI:10.1038/sj.onc.1207777
Reference
PMID:16484590
  Authors
Dong M, Blobe GC.
  Title
Role of transforming growth factor-beta in hematologic malignancies.
  Journal
Blood 107:4589-96 (2006)
DOI:10.1182/blood-2005-10-4169
Reference
PMID:9834202
  Authors
Kurokawa M, Mitani K, Imai Y, Ogawa S, Yazaki Y, Hirai H.
  Title
The t(3;21) fusion product, AML1/Evi-1, interacts with Smad3 and blocks transforming growth factor-beta-mediated growth inhibition of myeloid cells.
  Journal
Blood 92:4003-12 (1998)
Reference
PMID:12801837
  Authors
Brusa G, Benvenuti M, Mazzacurati L, Mancini M, Pattacini L, Martinelli G, Barbieri E, Greenberger JS, Baccarani M, Santucci MA.
  Title
p53 loss of function enhances genomic instability and accelerates clonal evolution of murine myeloid progenitors expressing the p(210)BCR-ABL tyrosine kinase.
  Journal
Haematologica 88:622-30 (2003)
Reference
PMID:11160144
  Authors
Baldwin AS.
  Title
Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kappaB.
  Journal
J Clin Invest 107:241-6 (2001)
DOI:10.1172/JCI11991
Reference
PMID:12244301
  Authors
Shin I, Yakes FM, Rojo F, Shin NY, Bakin AV, Baselga J, Arteaga CL.
  Title
PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localization.
  Journal
Nat Med 8:1145-52 (2002)
DOI:10.1038/nm759
Reference
PMID:15948971
  Authors
Tilli CM, Van Steensel MA, Krekels GA, Neumann HA, Ramaekers FC.
  Title
Molecular aetiology and pathogenesis of basal cell carcinoma.
  Journal
Br J Dermatol 152:1108-24 (2005)
DOI:10.1111/j.1365-2133.2005.06587.x
Reference
PMID:12588368
  Authors
Saldanha G, Fletcher A, Slater DN.
  Title
Basal cell carcinoma: a dermatopathological and molecular biological update.
  Journal
Br J Dermatol 148:195-202 (2003)
DOI:10.1046/j.1365-2133.2003.05151.x
Reference
PMID:15978322
  Authors
Daya-Grosjean L, Couve-Privat S.
  Title
Sonic hedgehog signaling in basal cell carcinomas.
  Journal
Cancer Lett 225:181-92 (2005)
DOI:10.1016/j.canlet.2004.10.003
Reference
PMID:15468170
  Authors
Tsai KY, Tsao H.
  Title
The genetics of skin cancer.
  Journal
Am J Med Genet C Semin Med Genet 131C:82-92 (2004)
DOI:10.1002/ajmg.c.30037
Reference
PMID:16881963
  Authors
Athar M, Tang X, Lee JL, Kopelovich L, Kim AL.
  Title
Hedgehog signalling in skin development and cancer.
  Journal
Exp Dermatol 15:667-77 (2006)
DOI:10.1111/j.1600-0625.2006.00473.x
Reference
PMID:16306523
  Authors
Rubin AI, Chen EH, Ratner D.
  Title
Basal-cell carcinoma.
  Journal
N Engl J Med 353:2262-9 (2005)
DOI:10.1056/NEJMra044151
Reference
PMID:11276000
  Authors
Saldanha G.
  Title
The Hedgehog signalling pathway and cancer.
  Journal
J Pathol 193:427-32 (2001)
DOI:10.1002/1096-9896(2000)9999:9999<::AID-PATH815>3.0.CO;2-N
Reference
PMID:15270885
  Authors
Saldanha G, Ghura V, Potter L, Fletcher A.
  Title
Nuclear beta-catenin in basal cell carcinoma correlates with increased proliferation.
  Journal
Br J Dermatol 151:157-64 (2004)
DOI:10.1111/j.1365-2133.2004.06048.x
Reference
PMID:14737121
  Authors
Pasca di Magliano M, Hebrok M.
  Title
Hedgehog signalling in cancer formation and maintenance.
  Journal
Nat Rev Cancer 3:903-11 (2003)
DOI:10.1038/nrc1229
Reference
PMID:15656799
  Authors
Reifenberger J, Wolter M, Knobbe CB, Kohler B, Schonicke A, Scharwachter C, Kumar K, Blaschke B, Ruzicka T, Reifenberger G.
  Title
Somatic mutations in the PTCH, SMOH, SUFUH and TP53 genes in sporadic basal cell carcinomas.
  Journal
Br J Dermatol 152:43-51 (2005)
DOI:10.1111/j.1365-2133.2005.06353.x
Reference
PMID:14556242
  Authors
Cohen MM Jr.
  Title
The hedgehog signaling network.
  Journal
Am J Med Genet A 123:5-28 (2003)
DOI:10.1002/ajmg.a.20495
Reference
PMID:11736900
  Authors
Yamazaki F, Aragane Y, Kawada A, Tezuka T.
  Title
Immunohistochemical detection for nuclear beta-catenin in sporadic basal cell carcinoma.
  Journal
Br J Dermatol 145:771-7 (2001)
DOI:10.1046/j.1365-2133.2001.04468.x
Reference
PMID:16054233
  Authors
Erb P, Ji J, Wernli M, Kump E, Glaser A, Buchner SA.
  Title
Role of apoptosis in basal cell and squamous cell carcinoma formation.
  Journal
Immunol Lett 100:68-72 (2005)
DOI:10.1016/j.imlet.2005.06.008
Reference
PMID:11130178
  Authors
Toftgard R.
  Title
Hedgehog signalling in cancer.
  Journal
Cell Mol Life Sci 57:1720-31 (2000)
DOI:10.1007/PL00000654
Reference
PMID:16822996
  Authors
Miller AJ, Mihm MC Jr.
  Title
Melanoma.
  Journal
N Engl J Med 355:51-65 (2006)
DOI:10.1056/NEJMra052166
Reference
PMID:12894244
  Authors
Chin L.
  Title
The genetics of malignant melanoma: lessons from mouse and man.
  Journal
Nat Rev Cancer 3:559-70 (2003)
DOI:10.1038/nrc1145
Reference
PMID:16750612
  Authors
Takata M, Saida T.
  Title
Genetic alterations in melanocytic tumors.
  Journal
J Dermatol Sci 43:1-10 (2006)
DOI:10.1016/j.jdermsci.2006.05.002
Reference
PMID:15841168
  Authors
Chudnovsky Y, Khavari PA, Adams AE.
  Title
Melanoma genetics and the development of rational therapeutics.
  Journal
J Clin Invest 115:813-24 (2005)
DOI:10.1172/JCI24808
Reference
PMID:16001050
  Authors
Merlino G.
  Title
Cancer biology: the weakest link?
  Journal
Nature 436:33-5 (2005)
DOI:10.1038/436033a
Reference
PMID:16001072
  Authors
Garraway LA, Widlund HR, Rubin MA, Getz G, Berger AJ, Ramaswamy S, Beroukhim R, Milner DA, Granter SR, Du J, Lee C, Wagner SN, Li C, Golub TR, Rimm DL, Meyerson ML, Fisher DE, Sellers WR.
  Title
Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma.
  Journal
Nature 436:117-22 (2005)
DOI:10.1038/nature03664
Reference
PMID:16899407
  Authors
Levy C, Khaled M, Fisher DE.
  Title
MITF: master regulator of melanocyte development and melanoma oncogene.
  Journal
Trends Mol Med 12:406-14 (2006)
DOI:10.1016/j.molmed.2006.07.008
Reference
PMID:15009714
  Authors
Tsao H, Goel V, Wu H, Yang G, Haluska FG.
  Title
Genetic interaction between NRAS and BRAF mutations and PTEN/MMAC1 inactivation in melanoma.
  Journal
J Invest Dermatol 122:337-41 (2004)
DOI:10.1046/j.0022-202X.2004.22243.x
Reference
PMID:11224709
  Authors
Gruss C, Herlyn M.
  Title
Role of cadherins and matrixins in melanoma.
  Journal
Curr Opin Oncol 13:117-23 (2001)
DOI:10.1097/00001622-200103000-00006
Reference
PMID:15721476
  Authors
Thompson JF, Scolyer RA, Kefford RF.
  Title
Cutaneous melanoma.
  Journal
Lancet 365:687-701 (2005)
DOI:10.1016/S0140-6736(05)17951-3
Reference
PMID:14695152
  Authors
Omholt K, Platz A, Kanter L, Ringborg U, Hansson J.
  Title
NRAS and BRAF mutations arise early during melanoma pathogenesis and are preserved throughout tumor progression.
  Journal
Clin Cancer Res 9:6483-8 (2003)
Reference
PMID:15557758
  Authors
Hussein MR.
  Title
The TP53 tumor suppressor gene and melanoma tumorigenesis: is there a relationship?
  Journal
Tumour Biol 25:200-7 (2004)
DOI:10.1159/000081103
Reference
PMID:10843728
  Authors
Lazar-Molnar E, Hegyesi H, Toth S, Falus A.
  Title
Autocrine and paracrine regulation by cytokines and growth factors in melanoma.
  Journal
Cytokine 12:547-54 (2000)
DOI:10.1006/cyto.1999.0614
Reference
PMID:16339096
  Authors
Cohen HT, McGovern FJ.
  Title
Renal-cell carcinoma.
  Journal
N Engl J Med 353:2477-90 (2005)
DOI:10.1056/NEJMra043172
Reference
PMID:15122209
  Authors
Pavlovich CP, Schmidt LS.
  Title
Searching for the hereditary causes of renal-cell carcinoma.
  Journal
Nat Rev Cancer 4:381-93 (2004)
DOI:10.1038/nrc1364
Reference
PMID:14634372
  Authors
Linehan WM, Walther MM, Zbar B.
  Title
The genetic basis of cancer of the kidney.
  Journal
J Urol 170:2163-72 (2003)
DOI:10.1097/01.ju.0000096060.92397.ed
Reference
PMID:14685170
  Authors
Birchmeier C, Birchmeier W, Gherardi E, Vande Woude GF.
  Title
Met, metastasis, motility and more.
  Journal
Nat Rev Mol Cell Biol 4:915-25 (2003)
DOI:10.1038/nrm1261
Reference
PMID:15611513
  Authors
Kim WY, Kaelin WG.
  Title
Role of VHL gene mutation in human cancer.
  Journal
J Clin Oncol 22:4991-5004 (2004)
DOI:10.1200/JCO.2004.05.061
Reference
PMID:17211469
  Authors
Sudarshan S, Linehan WM, Neckers L.
  Title
HIF and fumarate hydratase in renal cancer.
  Journal
Br J Cancer 96:403-7 (2007)
DOI:10.1038/sj.bjc.6603547
Reference
PMID:17287871
  Authors
Sudarshan S, Pinto PA, Neckers L, Linehan WM.
  Title
Mechanisms of disease: hereditary leiomyomatosis and renal cell cancer--a distinct form of hereditary kidney cancer.
  Journal
Nat Clin Pract Urol 4:104-10 (2007)
DOI:10.1038/ncpuro0711
Reference
PMID:12351585
  Authors
Bodmer D, van den Hurk W, van Groningen JJ, Eleveld MJ, Martens GJ, Weterman MA, van Kessel AG.
  Title
Understanding familial and non-familial renal cell cancer.
  Journal
Hum Mol Genet 11:2489-98 (2002)
DOI:10.1093/hmg/11.20.2489
Reference
PMID:17158541
  Authors
Mitra AP, Datar RH, Cote RJ.
  Title
Molecular pathways in invasive bladder cancer: new insights into mechanisms, progression, and target identification.
  Journal
J Clin Oncol 24:5552-64 (2006)
DOI:10.1200/JCO.2006.08.2073
Reference
PMID:16474624
  Authors
Wolff EM, Liang G, Jones PA.
  Title
Mechanisms of Disease: genetic and epigenetic alterations that drive bladder cancer.
  Journal
Nat Clin Pract Urol 2:502-10 (2005)
DOI:10.1038/ncpuro0318
Reference
PMID:16110317
  Authors
Wu XR.
  Title
Urothelial tumorigenesis: a tale of divergent pathways.
  Journal
Nat Rev Cancer 5:713-25 (2005)
DOI:10.1038/nrc1697
Reference
PMID:11103787
  Authors
Brown NS, Jones A, Fujiyama C, Harris AL, Bicknell R.
  Title
Thymidine phosphorylase induces carcinoma cell oxidative stress and promotes secretion of angiogenic factors.
  Journal
Cancer Res 60:6298-302 (2000)
Reference
PMID:12850530
  Authors
Bellmunt J, Hussain M, Dinney CP.
  Title
Novel approaches with targeted therapies in bladder cancer. Therapy of bladder cancer by blockade of the epidermal growth factor receptor family.
  Journal
Crit Rev Oncol Hematol 46 Suppl:S85-104 (2003)
DOI:10.1016/S1040-8428(03)00067-2
Reference
PMID:17149381
  Authors
Sugano K, Kakizoe T.
  Title
Genetic alterations in bladder cancer and their clinical applications in molecular tumor staging.
  Journal
Nat Clin Pract Urol 3:642-52 (2006)
DOI:10.1038/ncpuro0649
Reference
PMID:15746962
  Authors
Dunn KL, Espino PS, Drobic B, He S, Davie JR.
  Title
The Ras-MAPK signal transduction pathway, cancer and chromatin remodeling.
  Journal
Biochem Cell Biol 83:1-14 (2005)
DOI:10.1139/o04-121
Reference
PMID:15551095
  Authors
Williams SG, Stein JP.
  Title
Molecular pathways in bladder cancer.
  Journal
Urol Res 32:373-85 (2004)
DOI:10.1007/s00240-003-0345-y
Reference
PMID:12878745
  Authors
Nelson WG, De Marzo AM, Isaacs WB.
  Title
Prostate cancer.
  Journal
N Engl J Med 349:366-81 (2003)
DOI:10.1056/NEJMra021562
Reference
PMID:15724144
  Authors
Li L, Ittmann MM, Ayala G, Tsai MJ, Amato RJ, Wheeler TM, Miles BJ, Kadmon D, Thompson TC.
  Title
The emerging role of the PI3-K-Akt pathway in prostate cancer progression.
  Journal
Prostate Cancer Prostatic Dis 8:108-18 (2005)
DOI:10.1038/sj.pcan.4500776
Reference
PMID:16551847
  Authors
Pienta KJ, Bradley D.
  Title
Mechanisms underlying the development of androgen-independent prostate cancer.
  Journal
Clin Cancer Res 12:1665-71 (2006)
DOI:10.1158/1078-0432.CCR-06-0067
Reference
PMID:11900250
  Authors
Feldman BJ, Feldman D.
  Title
The development of androgen-independent prostate cancer.
  Journal
Nat Rev Cancer 1:34-45 (2001)
DOI:10.1038/35094009
Reference
PMID:15082523
  Authors
Heinlein CA, Chang C.
  Title
Androgen receptor in prostate cancer.
  Journal
Endocr Rev 25:276-308 (2004)
DOI:10.1210/er.2002-0032
Reference
PMID:9422516
  Authors
Koivisto P, Kolmer M, Visakorpi T, Kallioniemi OP.
  Title
Androgen receptor gene and hormonal therapy failure of prostate cancer.
  Journal
Am J Pathol 152:1-9 (1998)
Reference
PMID:10835690
  Authors
Zhao XY, Malloy PJ, Krishnan AV, Swami S, Navone NM, Peehl DM, Feldman D.
  Title
Glucocorticoids can promote androgen-independent growth of prostate cancer cells through a mutated androgen receptor.
  Journal
Nat Med 6:703-6 (2000)
DOI:10.1038/76287
Reference
PMID:10453277
  Authors
Macri E, Loda M.
  Title
Role of p27 in prostate carcinogenesis.
  Journal
Cancer Metastasis Rev 17:337-44 (1998)
DOI:10.1023/A:1006133620914
Reference
PMID:11750244
  Authors
Steers WD.
  Title
5alpha-reductase activity in the prostate.
  Journal
Urology 58:17-24; discussion 24 (2001)
DOI:10.1016/S0090-4295(01)01299-7
Reference
PMID:8069858
  Authors
Lin D, Meyer DJ, Ketterer B, Lang NP, Kadlubar FF.
  Title
Effects of human and rat glutathione S-transferases on the covalent DNA binding of the N-acetoxy derivatives of heterocyclic amine carcinogens in vitro: a possible mechanism of organ specificity in their carcinogenesis.
  Journal
Cancer Res 54:4920-6 (1994)
Reference
PMID:11527574
  Authors
Grimes CA, Jope RS.
  Title
The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling.
  Journal
Prog Neurobiol 65:391-426 (2001)
DOI:10.1016/S0301-0082(01)00011-9
Reference
PMID:15947972
  Authors
Ryan AJ, Susil B, Jobling TW, Oehler MK.
  Title
Endometrial cancer.
  Journal
Cell Tissue Res 322:53-61 (2005)
DOI:10.1007/s00441-005-1109-5
Reference
PMID:14747944
  Authors
Lax SF.
  Title
Molecular genetic pathways in various types of endometrial carcinoma: from a phenotypical to a molecular-based classification.
  Journal
Virchows Arch 444:213-23 (2004)
DOI:10.1007/s00428-003-0947-3
Reference
PMID:16508724
  Authors
Shiozawa T, Konishi I.
  Title
Early endometrial carcinoma: clinicopathology, hormonal aspects, molecular genetics, diagnosis, and treatment.
  Journal
Int J Clin Oncol 11:13-21 (2006)
DOI:10.1007/s10147-005-0546-1
Reference
PMID:17028294
  Authors
Hecht JL, Mutter GL.
  Title
Molecular and pathologic aspects of endometrial carcinogenesis.
  Journal
J Clin Oncol 24:4783-91 (2006)
DOI:10.1200/JCO.2006.06.7173
Reference
PMID:11431710
  Authors
Matias-Guiu X, Catasus L, Bussaglia E, Lagarda H, Garcia A, Pons C, Munoz J, Arguelles R, Machin P, Prat J.
  Title
Molecular pathology of endometrial hyperplasia and carcinoma.
  Journal
Hum Pathol 32:569-77 (2001)
DOI:10.1053/hupa.2001.25929
Reference
PMID:15284264
  Authors
Slomovitz BM, Broaddus RR, Burke TW, Sneige N, Soliman PT, Wu W, Sun CC, Munsell MF, Gershenson DM, Lu KH.
  Title
Her-2/neu overexpression and amplification in uterine papillary serous carcinoma.
  Journal
J Clin Oncol 22:3126-32 (2004)
DOI:10.1200/JCO.2004.11.154
Reference
PMID:7585656
  Authors
Saffari B, Jones LA, el-Naggar A, Felix JC, George J, Press MF.
  Title
Amplification and overexpression of HER-2/neu (c-erbB2) in endometrial cancers: correlation with overall survival.
  Journal
Cancer Res 55:5693-8 (1995)
Reference
PMID:16248975
  Authors
Kim D, Chung J.
  Title
Akt: versatile mediator of cell survival and beyond.
  Journal
J Biochem Mol Biol 35:106-15 (2002)
DOI:10.5483/bmbrep.2002.35.1.106
Reference
PMID:12711111
  Authors
Sanchez-Cespedes M.
  Title
Dissecting the genetic alterations involved in lung carcinogenesis.
  Journal
Lung Cancer 40:111-21 (2003)
DOI:10.1016/S0169-5002(03)00033-3
Reference
PMID:11720739
  Authors
Kaye FJ.
  Title
Molecular biology of lung cancer.
  Journal
Lung Cancer 34 Suppl 2:S35-41 (2001)
DOI:10.1016/S0169-5002(01)00342-7
Reference
PMID:12616528
  Authors
Shivapurkar N, Reddy J, Chaudhary PM, Gazdar AF.
  Title
Apoptosis and lung cancer: a review.
  Journal
J Cell Biochem 88:885-98 (2003)
DOI:10.1002/jcb.10440
Reference
PMID:11807782
  Authors
Sartorius UA, Krammer PH.
  Title
Upregulation of Bcl-2 is involved in the mediation of chemotherapy resistance in human small cell lung cancer cell lines.
  Journal
Int J Cancer 97:584-92 (2002)
DOI:10.1002/ijc.10096
Reference
PMID:16064138
  Authors
Adhikary S, Eilers M.
  Title
Transcriptional regulation and transformation by Myc proteins.
  Journal
Nat Rev Mol Cell Biol 6:635-45 (2005)
DOI:10.1038/nrm1703
Reference
PMID:11463388
  Authors
Spruck C, Strohmaier H, Watson M, Smith AP, Ryan A, Krek TW, Reed SI.
  Title
A CDK-independent function of mammalian Cks1: targeting of SCF(Skp2) to the CDK inhibitor p27Kip1.
  Journal
Mol Cell 7:639-50 (2001)
DOI:10.1016/S1097-2765(01)00210-6
Reference
PMID:15109562
  Authors
Buttery RC, Rintoul RC, Sethi T.
  Title
Small cell lung cancer: the importance of the extracellular matrix.
  Journal
Int J Biochem Cell Biol 36:1154-60 (2004)
DOI:10.1016/S1357-2725(03)00261-9
Reference
PMID:11559746
  Authors
Yamada KM, Araki M.
  Title
Tumor suppressor PTEN: modulator of cell signaling, growth, migration and apoptosis.
  Journal
J Cell Sci 114:2375-82 (2001)
Reference
PMID:11905738
  Authors
Rintoul RC, Sethi T.
  Title
The role of extracellular matrix in small-cell lung cancer.
  Journal
Lancet Oncol 2:437-42 (2001)
DOI:10.1016/S1470-2045(00)00421-6
Reference
PMID:12243753
  Authors
Ekedahl J, Joseph B, Grigoriev MY, Muller M, Magnusson C, Lewensohn R, Zhivotovsky B.
  Title
Expression of inhibitor of apoptosis proteins in small- and non-small-cell lung carcinoma cells.
  Journal
Exp Cell Res 279:277-90 (2002)
DOI:10.1006/excr.2002.5608
Reference
PMID:12379883
  Authors
Osada H, Takahashi T.
  Title
Genetic alterations of multiple tumor suppressors and oncogenes in the carcinogenesis and progression of lung cancer.
  Journal
Oncogene 21:7421-34 (2002)
DOI:10.1038/sj.onc.1205802
Reference
PMID:12741677
  Authors
Yokota J, Nishioka M, Tani M, Kohno T.
  Title
Genetic alterations responsible for metastatic phenotypes of lung cancer cells.
  Journal
Clin Exp Metastasis 20:189-93 (2003)
DOI:10.1023/a:1022978932215
Reference
PMID:16870043
  Authors
Aviel-Ronen S, Blackhall FH, Shepherd FA, Tsao MS.
  Title
K-ras mutations in non-small-cell lung carcinoma: a review.
  Journal
Clin Lung Cancer 8:30-8 (2006)
DOI:10.3816/CLC.2006.n.030
Reference
PMID:15948711
  Authors
Pfeifer GP, Dammann R.
  Title
Methylation of the tumor suppressor gene RASSF1A in human tumors.
  Journal
Biochemistry (Mosc) 70:576-83 (2005)
DOI:10.1007/s10541-005-0151-y
Reference
PMID:11902573
  Authors
Altucci L, Gronemeyer H.
  Title
The promise of retinoids to fight against cancer.
  Journal
Nat Rev Cancer 1:181-93 (2001)
DOI:10.1038/35106036
Reference
PMID:10944551
  Authors
Virmani AK, Rathi A, Zochbauer-Muller S, Sacchi N, Fukuyama Y, Bryant D, Maitra A, Heda S, Fong KM, Thunnissen F, Minna JD, Gazdar AF.
  Title
Promoter methylation and silencing of the retinoic acid receptor-beta gene in lung carcinomas.
  Journal
J Natl Cancer Inst 92:1303-7 (2000)
DOI:10.1093/jnci/92.16.1303
Reference
PMID:12867060
  Authors
Hirsch FR, Scagliotti GV, Langer CJ, Varella-Garcia M, Franklin WA.
  Title
Epidermal growth factor family of receptors in preneoplasia and lung cancer: perspectives for targeted therapies.
  Journal
Lung Cancer 41 Suppl 1:S29-42 (2003)
DOI:10.1016/S0169-5002(03)00137-5
Reference
PMID:16112428
  Authors
Panani AD, Roussos C.
  Title
Cytogenetic and molecular aspects of lung cancer.
  Journal
Cancer Lett 239:1-9 (2006)
DOI:10.1016/j.canlet.2005.06.030
Reference
PMID:12407699
  Authors
Mitsuuchi Y, Testa JR.
  Title
Cytogenetics and molecular genetics of lung cancer.
  Journal
Am J Med Genet 115:183-8 (2002)
DOI:10.1002/ajmg.10692
Reference
PMID:15942304
  Authors
Breuer RH, Postmus PE, Smit EF.
  Title
Molecular pathology of non-small-cell lung cancer.
  Journal
Respiration 72:313-30 (2005)
DOI:10.1159/000085376
Reference
PMID:11895903
  Authors
Piyathilake CJ, Frost AR, Manne U, Weiss H, Bell WC, Heimburger DC, Grizzle WE.
  Title
Differential expression of growth factors in squamous cell carcinoma and precancerous lesions of the lung.
  Journal
Clin Cancer Res 8:734-44 (2002)
Reference
PMID:16189154
  Authors
Awaya H, Takeshima Y, Furonaka O, Kohno N, Inai K.
  Title
Gene amplification and protein expression of EGFR and HER2 by chromogenic in situ hybridisation and immunohistochemistry in atypical adenomatous hyperplasia and adenocarcinoma of the lung.
  Journal
J Clin Pathol 58:1076-80 (2005)
DOI:10.1136/jcp.2004.025585
Reference
PMID:21193867
  Authors
Lappano R, Maggiolini M
  Title
G protein-coupled receptors: novel targets for drug discovery in cancer.
  Journal
Nat Rev Drug Discov 10:47-60 (2011)
DOI:10.1038/nrd3320
Reference
PMID:24508914
  Authors
O'Hayre M, Degese MS, Gutkind JS
  Title
Novel insights into G protein and G protein-coupled receptor signaling in cancer.
  Journal
Curr Opin Cell Biol 27:126-35 (2014)
DOI:10.1016/j.ceb.2014.01.005
Reference
PMID:17251915
  Authors
Dorsam RT, Gutkind JS
  Title
G-protein-coupled receptors and cancer.
  Journal
Nat Rev Cancer 7:79-94 (2007)
DOI:10.1038/nrc2069
Related
pathway
cjc03320  PPAR signaling pathway
cjc04010  MAPK signaling pathway
cjc04020  Calcium signaling pathway
cjc04024  cAMP signaling pathway
cjc04060  Cytokine-cytokine receptor interaction
cjc04066  HIF-1 signaling pathway
cjc04110  Cell cycle
cjc04115  p53 signaling pathway
cjc04150  mTOR signaling pathway
cjc04151  PI3K-Akt signaling pathway
cjc04210  Apoptosis
cjc04310  Wnt signaling pathway
cjc04330  Notch signaling pathway
cjc04340  Hedgehog signaling pathway
cjc04350  TGF-beta signaling pathway
cjc04370  VEGF signaling pathway
cjc04510  Focal adhesion
cjc04512  ECM-receptor interaction
cjc04520  Adherens junction
cjc04630  JAK-STAT signaling pathway
cjc04915  Estrogen signaling pathway
KO pathway
ko05200   
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