KEGG ORTHOLOGY: K04968

ORTHOLOGY: K04968

Entry

K04968                      KO

Symbol

TRPC5

Name

transient receptor potential cation channel subfamily C member 5

Pathway

map04360

Axon guidance

map04929

GnRH secretion

Brite

KEGG Orthology (KO) [BR:ko00001]
09150 Organismal Systems
  09152 Endocrine system
   04929 GnRH secretion
    K04968  TRPC5; transient receptor potential cation channel subfamily C member 5
  09158 Development and regeneration
   04360 Axon guidance
    K04968  TRPC5; transient receptor potential cation channel subfamily C member 5
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins
    K04968  TRPC5; transient receptor potential cation channel subfamily C member 5
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K04968  TRPC5; transient receptor potential cation channel subfamily C member 5
Protein phosphatases and associated proteins [BR:ko01009]
Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     K04968  TRPC5; transient receptor potential cation channel subfamily C member 5
Ion channels [BR:ko04040]
Voltage-gated cation channels
  Transient receptor potential channel (TRP)
   K04968  TRPC5; transient receptor potential cation channel subfamily C member 5

Other DBs

GO:

0015279

TC:

1.A.4.1.7

Genes

HSA:	7224(TRPC5)

PTR:	465813(TRPC5)

PPS:	100991195(TRPC5)

GGO:	101144610(TRPC5)

PON:	100437515(TRPC5)

PPYG:

129024248(TRPC5)

NLE:	100597182(TRPC5)

HMH:	116811156(TRPC5)

SSYN:

129475838(TRPC5)

MCC:	707171(TRPC5)

MCF:	102116388(TRPC5)

MTHB:

126946460

MNI:	105490484(TRPC5)

CSAB:

103232502(TRPC5)

CATY:

105598436(TRPC5)

PANU:

101008032(TRPC5)

TGE:	112616437(TRPC5)

MLEU:

105542804(TRPC5)

RRO:	104668597(TRPC5)

RBB:	108529812(TRPC5)

TFN:	117077926(TRPC5)

PTEH:

111536640(TRPC5)

CANG:

105519979(TRPC5)

CJC:	100384971(TRPC5)

SBQ:	101054206(TRPC5)

CIMI:

108285150(TRPC5)

ANAN:

105716887(TRPC5)

CSYR:

103259530(TRPC5)

MMUR:

105862991(TRPC5)

LCAT:

123627958(TRPC5)

ERUF:

138378297(TRPC5)

PCOQ:

105810737(TRPC5)

OGA:	100955932(TRPC5)

MMU:	22067(Trpc5)

MCAL:

110286568(Trpc5)

MPAH:

110313829(Trpc5)

RNO:	140933(Trpc5)

MCOC:

116089333(Trpc5)

ANU:	117694664(Trpc5)

ASYL:

127674970(Trpc5)

MUN:	110565916(Trpc5)

CGE:	100754603(Trpc5)

MAUA:

101827268(Trpc5)

PROB:

127217997(Trpc5)

PLEU:

114698311(Trpc5)

PMAV:

102904386(Trpc5)

MORG:

121437522 121444028

MFOT:

126491500

AAMP:

119805077(Trpc5)

CNL:	130867765(Trpc5)

NGI:	103740890(Trpc5)

HGL:	101709576(Trpc5)

CPOC:

100719495(Trpc5)

CCAN:

109675359

DORD:

105992796(Trpc5)

DSP:	122116394(Trpc5)

DMER:

138840121(Trpc5)

PLOP:

125343618(Trpc5)

NCAR:

124972009

MMMA:

125614291

ITI:	101978094(Trpc5)

OCU:	100009574(TRPC5)

OPI:	101533111(TRPC5)

OCZ:	121169367(TRPC5)

TUP:	102468729(TRPC5)

GVR:	103594675(TRPC5)

CFA:	492072(TRPC5)

CLUD:

112649291(TRPC5)

VVP:	112932051(TRPC5)

VLG:	121483210(TRPC5)

NPO:	129518470(TRPC5)

AML:	100480493(TRPC5)

UMR:	103679736(TRPC5)

UAH:	113241245(TRPC5)

UAR:	123786195(TRPC5)

ELK:

111160972

LLV:

125092140

MPUF:

101691650(TRPC5)

MNP:	132006739(TRPC5)

MLK:	131821749(TRPC5)

NVS:	122896345(TRPC5)

ORO:	101366578(TRPC5)

EJU:	114200242(TRPC5)

ZCA:	113931514(TRPC5)

MLX:	118012131(TRPC5)

NSU:	110576395(TRPC5)

FCA:	101096211(TRPC5)

PYU:	121025730(TRPC5)

PCOO:

112870896(TRPC5)

PBG:	122476959(TRPC5)

PVIV:

125157274(TRPC5)

LRUF:

124514012

LGF:	123594568(TRPC5)

AJU:

106985611

PTG:	102961651(TRPC5)

PPAD:

109253680(TRPC5)

PUC:

125931912

HHV:	120241986(TRPC5)

BTA:	407103(TRPC5)

BOM:	102276500(TRPC5)

BIU:	109555515(TRPC5)

BKE:	129639255(TRPC5)

CHX:	102185159(TRPC5)

OAS:	101109334(TRPC5)

BTAX:

128070029(TRPC5)

CSUM:

138070962(TRPC5)

ODA:	120881402(TRPC5)

CCAD:

122434967(TRPC5)

MREE:

136153513(TRPC5)

OVR:	110129869(TRPC5)

MBEZ:

129534929(TRPC5)

SSC:	100037962(TRPC5)

CFR:	102522361(TRPC5)

CBAI:

105079088(TRPC5)

CDK:

116150923

BACU:

103012125

BMUS:

118888655(TRPC5)

LVE:	103079164(TRPC5)

OOR:	101274142(TRPC5)

LALB:

132513941(TRPC5)

GMF:	115841623(TRPC5)

DDP:	132418633(TRPC5)

DLE:	111165778(TRPC5)

PCAD:

102994361(TRPC5)

PSIU:

116747542(TRPC5)

PPHC:

136143108(TRPC5)

NASI:

112402323(TRPC5)

ECB:	100054221(TRPC5)

EPZ:	103567201(TRPC5)

EAI:	106845123(TRPC5)

MYB:	102258816(TRPC5)

MYD:	102754376(TRPC5)

MMYO:

118654619(TRPC5)

MLF:	102435776(TRPC5)

MDT:	132224513(TRPC5)

PKL:	118728190(TRPC5)

EFUS:

103301606(TRPC5)

MNA:	107525837(TRPC5)

DRO:	112303544(TRPC5)

AJM:	119047164(TRPC5)

PHAS:

123805146(TRPC5)

MMF:	118636224(TRPC5)

PPAM:

129076174(TRPC5)

HAI:	109376415(TRPC5)

RFQ:	117025614(TRPC5)

PALE:

102885596(TRPC5)

PGIG:

120612310(TRPC5)

PVP:	105301602(TRPC5)

RAY:	107497737(TRPC5)

MJV:	108396647(TRPC5)

TOD:	119245958(TRPC5)

SARA:

101557785(TRPC5)

SFUM:

130034223(TRPC5)

SETR:

125999497(TRPC5)

LAV:	100667983(TRPC5)

TMU:

101355447

ETF:	101659540(TRPC5)

DNM:	101440710(TRPC5)

MDO:

100011748

GAS:	123253419(TRPC5)

SHR:	100922422(TRPC5)

AFZ:

127542500

PCW:	110203356(TRPC5)

PBRV:

138143971(TRPC5)

MLAO:

141498571 141499848

OAA:	100073537(TRPC5)

TACU:

119929695(TRPC5)

GGA:	422337(TRPC5)

PCOC:

116229764(TRPC5)

MGP:	100549886(TRPC5)

CJO:	107312856(TRPC5)

TPAI:

128076003(TRPC5)

LMUT:

125699974(TRPC5)

NMEL:

110403323(TRPC5)

APLA:

101795387(TRPC5)

AACU:

137863700(TRPC5)

ACYG:

106038587(TRPC5)

CATA:

118245393(TRPC5)

AFUL:

116494429(TRPC5)

TGU:	100226499(TRPC5)

LSR:	110467869(TRPC5)

SCAN:

103816347(TRPC5)

PMOA:

120512700(TRPC5)

OTC:	121346496(TRPC5)

PRUF:

121362839(TRPC5)

ATRC:

139597399(TRPC5)

GFR:	102036976(TRPC5)

FAB:	101813227(TRPC5)

OMA:	130253085(TRPC5)

PHI:	102106507(TRPC5)

PMAJ:

107204057(TRPC5)

CCAE:

111929213(TRPC5)

CCW:	104691623(TRPC5)

CBRC:

103617916(TRPC5)

ACOE:

138110246(TRPC5)

ETL:	114062088(TRPC5)

ZAB:	102061091(TRPC5)

ZLE:	135447890(TRPC5)

ACHL:

103803639(TRPC5)

SVG:	106853771(TRPC5)

MMEA:

130575926(TRPC5)

HRT:	120762024(TRPC5)

SATI:

136370494(TRPC5)

CFAI:

136300169(TRPC5)

CCIC:

134049895(TRPC5)

FPG:	101916426(TRPC5)

FCH:	102055753(TRPC5)

CCRI:

104163111

NNT:

104411320

SHAB:

115613118(TRPC5)

ACUN:

113480097(TRPC5)

SURA:

141949160(TRPC5)

TALA:

104359035(TRPC5)

ACHC:

115333816(TRPC5)

HALD:

104318890(TRPC5)

HLE:	104832704(TRPC5)

AGEN:

126050107

HHAR:

128153928(TRPC5)

BBUT:

142043051(TRPC5)

GCL:

127019578

CSTI:

104561581(TRPC5)

LDI:	104348993(TRPC5)

MNB:	103776368(TRPC5)

DPUB:

104300143(TRPC5)

PPUS:

135183989(TRPC5)

AVIT:

104281283

BRHI:

104495790(TRPC5)

EGZ:	104135703(TRPC5)

NNI:	104023225(TRPC5)

PCRI:

104032159

PCAO:

104042093

PADL:

103920165(TRPC5)

AFOR:

103896622(TRPC5)

FGA:

104081341

CBOR:

142087521(TRPC5)

GSTE:

104264600

CBOY:

140658431(TRPC5)

MAME:

142415232(TRPC5)

CLV:	102086995(TRPC5)

CNIC:

135993396(TRPC5)

MUI:	104544318(TRPC5)

PGUU:

104457442

PLET:

104627787(TRPC5)

EHS:

104513925

CMAC:

104484718

CUCA:

104058265(TRPC5)

TEO:

104372237

BREG:

104639641(TRPC5)

GAME:

129211998(TRPC5)

OHA:	104339090(TRPC5)

ACAR:

104525208

CPEA:

104388296(TRPC5)

CVF:	104291485(TRPC5)

RTD:	128915117(TRPC5)

CRID:

134520694(TRPC5)

LMIC:

141748636(TRPC5)

NARQ:

141464334(TRPC5)

AAM:	106494782(TRPC5)

AROW:

112975804(TRPC5)

NPD:	112951781(TRPC5)

TGT:	104579971(TRPC5)

DNE:	112982472(TRPC5)

SCAM:

104150932(TRPC5)

ASN:	102381911(TRPC5)

AMJ:	102571478(TRPC5)

CPOO:

109313703(TRPC5)

GGN:	109300359(TRPC5)

PSS:	102454026(TRPC5)

CIZ:	142020091(TRPC5)

CMY:	102944890(TRPC5)

CCAY:

125642649(TRPC5)

LKP:	140917739(TRPC5)

NDS:	141993136(TRPC5)

DCC:	119861914(TRPC5)

CPIC:

101947489(TRPC5)

TST:	117883411(TRPC5)

CABI:

116817156(TRPC5)

MRV:	120371316(TRPC5)

ACS:	100553009(trpc5)

ASAO:

132762937(TRPC5)

PVT:	110074272(TRPC5)

SUND:

121936708(TRPC5)

PBI:	103051446(TRPC5)

PMUR:

107289819(TRPC5)

CTIG:

120316252

TSR:	106542283(TRPC5)

PGUT:

117675974(TRPC5)

PCAE:

139322699(TRPC5)

APRI:

131183844(TRPC5)

PTEX:

113437928(TRPC5)

NSS:	113419280(TRPC5)

VKO:	123022031(TRPC5)

PMUA:

114588936(TRPC5)

PRAF:

128406597(TRPC5)

ZVI:	118083728(TRPC5)

HCG:	128335457(TRPC5)

GJA:

107123374

STOW:

125442922(TRPC5)

EMC:	129341376(TRPC5)

XLA:	108698404 108700107

XTR:	100493720(trpc5)

NPR:	108794565(TRPC5)

RTEM:

120913711(TRPC5)

ACAT:

141108104(TRPC5)

PADS:

140343292(TRPC5)

BBUF:

121009517(TRPC5)

BGAR:

122946771(TRPC5)

DTC:

141073625

PWL:	138261793(TRPC5)

MUO:	115474126(TRPC5)

GSH:	117361127(TRPC5)

DRE:	557456(trpc5a) 559586(trpc5b)

SRX:	107713133 107723160 107727288 107758875

SANH:

107661741 107663369 107665932 107692628

SGH:	107564287 107581989 107587277 107590730

CCAR:

109058718 109084581 109086097 109088128

CAUA:

113038172 113044489 113063897 113109382

CGIB:

127942017 127949211 127979120 127985399

PTET:

122326828 122344663(trpc5a)

LROH:

127152831 127167233(trpc5a)

GRF:

141292570

OMC:	131528883 131548561(trpc5a)

PPRM:

120463815(trpc5a) 120482030

RKG:	130095573 130097616(trpc5a)

MAMB:

125253108 125272774(trpc5a)

CIDE:

127503546 127519915

CERY:

137012573 137031729(trpc5a)

MASI:

127428828 127431044 127443405 127445225

TROS:

130553401(trpc5a) 130570423

TDW:	130407587 130440272(trpc5a)

MANU:

129424011 129444908(trpc5a)

PDAB:

135735791(trpc5a) 135776525

IPU:	108261176(trpc5a)

IFU:

128622106

PHYP:

113542970

SMEO:

124398405(trpc5a)

TFD:	113638629(trpc5a)

TVC:	132860373(trpc5a)

CGAR:

128507503(trpc5a)

NGRA:

132895332

TRN:	134330244(trpc5a)

AMEX:

103044006(trpc5a) 111191472

CMAO:

118802026(trpc5a) 118820011

EEE:	113574938 113590395

CHAR:

105896227(trpc5a)

SPIL:

134079592

ASAD:

121709926(trpc5a)

TRU:

101077030

TFS:	130522136(trpc5a)

TNG:	GSTEN00021202G001

LCO:

104937034

TBEN:

117470620

PGEO:

117440870

EMAC:

134876150(trpc5a)

ELY:	117245819(trpc5a)

EFO:	125883612(trpc5a)

SLUC:

116053361(trpc5a)

ECRA:

117934993(trpc5a)

ESP:

116669495

PFLV:

114545360

GAT:

120821473

PPUG:

119222878(trpc5a)

AFB:	129093834(trpc5a)

CLUM:

117748122(trpc5a)

PSWI:

130211698(trpc5a)

CANA:

137792021(trpc5a)

CVE:

137878097

MSAM:

119911933(trpc5a)

SCHU:

122869718(trpc5a)

EARM:

139305603(trpc5a)

CUD:	121504334(trpc5a)

SPUL:

138601245(trpc5a)

LMIX:

132958375(trpc5a)

HTC:	141811283(trpc5a)

ALAT:

119026989(trpc5a)

ASTR:

137590805(trpc5a)

PKLU:

139222646(trpc5a)

MZE:

101473674

ONL:

100707123

OAU:	116334378(trpc5a)

OLA:

101169488

OML:	112155728(trpc5a)

CSAI:

133419961(trpc5a)

XMA:

XCO:

XHE:

PRET:

PFOR:

PLAI:

PMEI:

GAF:	122820703(trpc5a)

PPRL:

129379881(trpc5a)

CVG:	107089402(trpc5)

CTUL:

119792398(trpc5a)

GMU:	124881057(trpc5a)

NFU:

107376789

KMR:	108248215(trpc5a)

ALIM:

106523850

NWH:	119413434(trpc5a)

AOCE:

111566578(trpc5a)

EJA:	138211919(trpc5a)

BFRE:

138632443(trpc5a)

MCEP:

125022169(trpc5a)

CSEM:

103389248

SSEN:

122766302(trpc5a)

SSOE:

131457044(trpc5a)

HHIP:

117751833(trpc5a)

HSP:	118102876(trpc5a)

PPLT:

128430571(trpc5a)

SMAU:

118283591(trpc5a)

LCF:	108902790(trpc5a)

SDU:

111233323

SLAL:

111665400

XGL:	120797430(trpc5a)

HCQ:

109511912

SSCV:

125982661(trpc5a)

SBIA:

133494887(trpc5a)

PEE:	133397655(trpc5a)

PTAO:

133472698(trpc5a)

BPEC:

110173258

ENY:	140371890(trpc5a)

MALB:

109965827(trpc5)

BSPL:

114849847(trpc5a)

SJO:	128384232(trpc5a)

SSCO:

134005882(trpc5a)

TTY:	137175187(trpc5a)

GMH:

115529877

SASA:

106563669 106578151 106578157 106591872 106602946

STRU:

115154873(trpc5) 115186275 115204490

OTW:	112229054 112231140 112239624

OMY:	110510170 110516497 110531293 110534166

OGO:	124005850 124007486 124008850 124013886

ONE:	115126941 115135473

OKI:	109873172 109873656 109885371

OKE:	118379866 118385741 118390534 127915540

OMM:	135516493 135544120 135550261

OCLA:

139388094 139398399 139398405 139417023 139419609

SALP:

111950011 111964385

SNH:	120021690 120030518 120056649

SFON:

129869097

CCLU:

121542129 121558819 121579643

ELS:	105009201 105024647

OEP:

134013859

SFM:

108934328

PKI:	111841890 111859209

AANG:

118234976(trpc5a)

AROT:

135262334(trpc5a)

CCOG:

133132225

LOC:	102692345(trpc5)

PSPA:

121295295 121318656

ARUT:

117411806 117430198

PSEX:

120537536(trpc5a)

LCM:

CMK:

RTP:

CPLA:

CPUN:

HOC:

SCAU:

STOZ:

LERI:

HAKA:

PMRN:

116942852(TRPC4) 116943590

LRJ:	133342874 133350029

BFO:	118415173 118416198 118416199

BBEL:

109468336 109476747 109477079 109477279

SCLV:

120329457

CLEP:

143445957 143459494 143468676

SPU:	585901 589158

LPIC:

129267346

LVG:	121415761 121420485 121429051

AJJ:

APLC:

ARUN:

AAMU:

AFIL:

140139817 140151722 140153193

AJC:

117119227

PFLL:

139116009 139116627 139128015 139133149 139133335 139133356 139135451

AME:

ACER:

ALAB:

OBB:

OLG:

MGEN:

CCOA:

TCZ:

TSEP:

COBS:

TLN:

TAME:

FEX:

PMEC:

PGC:

PCF:

PFUC:

VPS:

VCRB:

VVE:

FAS:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

SOY:

CSET:

DVV:

APLN:

OTU:

SLIU:

OFU:

ATRA:

LGLY:

CSTB:

MQU:

LSM:

PPOI:

VDE:

VJA:

CVS:	136969840 136970500 136978596 136978645 136979362 136983897 136987427

ABRU:

129958613 129958614 129980731

UDV:	129219137 129223023

SDM:

LPOL:

PMEO:

LLON:

EPA:	110234877 110235458 110236206

ATEN:

116305460

ADF:

107340132

AMIL:

114950830 114962229 114973713 114975006 122958366

PDAM:

113671454 113672141 113674742

SPIS:

111330789 111336295 111342127 111343010

DGT:

XEN:

HMG:

Reference

PMID:16284075

Authors

Shimizu S, Yoshida T, Wakamori M, Ishii M, Okada T, Takahashi M, Seto M, Sakurada K, Kiuchi Y, Mori Y

Title

Ca2+-calmodulin-dependent myosin light chain kinase is essential for activation of TRPC5 channels expressed in HEK293 cells.

Journal

J Physiol 570:219-35 (2006)
DOI:10.1113/jphysiol.2005.097998

Sequence

[hsa:7224]

LinkDB

DBGET integrated database retrieval system