KEGG   PATHWAY: pleu05200
Entry
pleu05200                   Pathway                                
Name
Pathways in cancer - Peromyscus leucopus (white-footed mouse)
Class
Human Diseases; Cancer: overview
Pathway map
pleu05200  Pathways in cancer
pleu05200

Organism
Peromyscus leucopus (white-footed mouse) [GN:pleu]
Gene
114690209  Dcc; netrin receptor DCC isoform X1 [KO:K06765]
114693817  Casp3; caspase-3 isoform X1 [KO:K02187] [EC:3.4.22.56]
114700859  Casp9; caspase-9 isoform X1 [KO:K04399] [EC:3.4.22.62]
114702126  Appl1; DCC-interacting protein 13-alpha [KO:K08733]
114683440  cadherin-1 [KO:K05689]
114681270  Ctnnb1; catenin beta-1 isoform X1 [KO:K02105]
114705104  Ctnna1; catenin alpha-1 isoform X1 [KO:K05691]
114701114  Ctnna3; catenin alpha-3 isoform X2 [KO:K05691]
114694443  Ctnna2; LOW QUALITY PROTEIN: catenin alpha-2 [KO:K05691]
114709466  Axin1; axin-1 isoform X1 [KO:K02157]
114690442  Axin2; axin-2 [KO:K04385]
114684081  Apc2; LOW QUALITY PROTEIN: adenomatous polyposis coli protein 2 [KO:K02085]
114705120  Apc; adenomatous polyposis coli protein isoform X1 [KO:K02085]
114701479  Gsk3b; glycogen synthase kinase-3 beta isoform X1 [KO:K03083] [EC:2.7.11.26]
114683055  Tcf7; transcription factor 7 isoform X2 [KO:K02620]
114681591  Tcf7l1; transcription factor 7-like 1 isoform X1 [KO:K04490]
114697060  Tcf7l2; transcription factor 7-like 2 isoform X1 [KO:K04491]
114682816  Lef1; lymphoid enhancer-binding factor 1 isoform X1 [KO:K04492]
114708968  Birc5; baculoviral IAP repeat-containing protein 5 isoform X1 [KO:K08731]
114701991  Myc; myc proto-oncogene protein [KO:K04377]
114694498  Ccnd1; G1/S-specific cyclin-D1 isoform X2 [KO:K04503]
114708572  Wnt1; proto-oncogene Wnt-1 [KO:K03209]
114707263  Wnt2b; protein Wnt-2b [KO:K00182]
114694717  Wnt2; protein Wnt-2 [KO:K00182]
114682971  Wnt3a; protein Wnt-3a [KO:K00312]
114702271  Wnt3; proto-oncogene Wnt-3 [KO:K00312]
114697207  Wnt4; protein Wnt-4 [KO:K00408]
114700757  Wnt5b; protein Wnt-5b [KO:K00444]
114702120  Wnt5a; protein Wnt-5a isoform X1 [KO:K00444]
114709311  Wnt6; protein Wnt-6 [KO:K00445]
114681319  Wnt7a; protein Wnt-7a [KO:K00572]
114699199  Wnt7b; protein Wnt-7b isoform X1 [KO:K00572]
114705144  Wnt8a; protein Wnt-8a [KO:K00714]
114708149  Wnt8b; protein Wnt-8b [KO:K00714]
114683006  Wnt9a; protein Wnt-9a [KO:K01064]
114702202  Wnt9b; protein Wnt-9b [KO:K01064]
114708546  Wnt10b; protein Wnt-10b [KO:K01357]
114709307  Wnt10a; LOW QUALITY PROTEIN: protein Wnt-10a [KO:K01357]
114698691  Wnt11; protein Wnt-11 isoform X1 [KO:K01384]
114695609  Wnt16; protein Wnt-16 [KO:K01558]
114685753  Fzd7; frizzled-7 [KO:K02432]
114687963  Fzd1; frizzled-1 [KO:K02432]
114702239  Fzd2; frizzled-2 [KO:K02235]
114707293  Fzd3; frizzled-3 isoform X1 [KO:K02329]
114710708  Fzd4; frizzled-4 [KO:K02354]
114705069  Fzd5; frizzled-5 [KO:K02375]
114695763  Fzd8; frizzled-8 [KO:K02375]
114699911  Fzd6; frizzled-6 [KO:K02376]
114686016  Fzd9; frizzled-9 [KO:K02842]
114693690  Fzd10; frizzled-10 [KO:K02842]
114694590  Lrp5; low-density lipoprotein receptor-related protein 5 isoform X1 [KO:K03068]
114710353  Lrp6; low-density lipoprotein receptor-related protein 6 isoform X1 [KO:K03068]
114683308  Dvl3; segment polarity protein dishevelled homolog DVL-3 isoform X1 [KO:K02353]
114693209  Dvl2; LOW QUALITY PROTEIN: segment polarity protein dishevelled homolog DVL-2 [KO:K02353]
114708251  Dvl1; segment polarity protein dishevelled homolog DVL-1 isoform X1 [KO:K02353]
114706884  proto-oncogene FRAT1 [KO:K03069]
114706894  LOW QUALITY PROTEIN: GSK-3-binding protein FRAT2-like [KO:K03096]
114699696  F2; prothrombin [KO:K01313] [EC:3.4.21.5]
114707150  Agt; angiotensinogen [KO:K09821]
114694648  F2r; proteinase-activated receptor 1 [KO:K03914]
114702904  proteinase-activated receptor 1-like [KO:K03914]
114709559  F2rl3; proteinase-activated receptor 4 [KO:K04236]
114683458  Lpar1; lysophosphatidic acid receptor 1 isoform X1 [KO:K04289]
114682879  lysophosphatidic acid receptor 2 [KO:K04291]
114686692  LOW QUALITY PROTEIN: lysophosphatidic acid receptor 2-like [KO:K04291]
114698275  Lpar3; lysophosphatidic acid receptor 3 [KO:K04294]
114704891  Lpar4; lysophosphatidic acid receptor 4 [KO:K04275]
114708819  Lpar5; lysophosphatidic acid receptor 5 [KO:K08390]
114698794  Lpar6; lysophosphatidic acid receptor 6 [KO:K04273]
114686251  Agtr1; type-1 angiotensin II receptor [KO:K04166]
114701075  type-1A angiotensin II receptor [KO:K04166]
114705518  Gna12; guanine nucleotide-binding protein subunit alpha-12 [KO:K04346]
114690445  Gna13; guanine nucleotide-binding protein subunit alpha-13 isoform X1 [KO:K04639]
114691150  Arhgef12; rho guanine nucleotide exchange factor 12 isoform X1 [KO:K07532]
114683346  Arhgef11; rho guanine nucleotide exchange factor 11 isoform X1 [KO:K12331]
114686813  Arhgef1; rho guanine nucleotide exchange factor 1 isoform X1 [KO:K12330]
114702619  Plekhg5; LOW QUALITY PROTEIN: pleckstrin homology domain-containing family G member 5 [KO:K19464]
114705216  Rhoa; transforming protein RhoA [KO:K04513]
114700910  transforming protein RhoA-like [KO:K04513]
114698172  Rock1; rho-associated protein kinase 1 [KO:K04514] [EC:2.7.11.1]
114698838  Rock2; rho-associated protein kinase 2 isoform X1 [KO:K17388] [EC:2.7.11.1]
114689656  Cxcl12; stromal cell-derived factor 1 isoform X1 [KO:K10031]
114696964  Cxcr4; C-X-C chemokine receptor type 4 isoform X1 [KO:K04189]
114710969  Gnai2; guanine nucleotide-binding protein G(i) subunit alpha-2 [KO:K04630]
114699988  Gnai3; guanine nucleotide-binding protein G(i) subunit alpha [KO:K04630]
114708228  Gnai1; guanine nucleotide-binding protein G(i) subunit alpha-1 [KO:K04630]
114688217  Ptger1; prostaglandin E2 receptor EP1 subtype [KO:K04258]
114696004  Ptger2; prostaglandin E2 receptor EP2 subtype [KO:K04259]
114707610  Ptger3; prostaglandin E2 receptor EP3 subtype isoform X1 [KO:K04260]
114697342  Ptger4; prostaglandin E2 receptor EP4 subtype [KO:K04261]
114682025  neuroendocrine secretory protein 55-like [KO:K04632]
114682029  guanine nucleotide-binding protein G(s) subunit alpha isoform X1 [KO:K04632]
114693962  Adcy1; adenylate cyclase type 1 [KO:K08041] [EC:4.6.1.1]
114696121  Adcy2; adenylate cyclase type 2 isoform X1 [KO:K08042] [EC:4.6.1.1]
114697107  Adcy3; adenylate cyclase type 3 isoform X1 [KO:K08043] [EC:4.6.1.1]
114708701  Adcy4; adenylate cyclase type 4 [KO:K08044] [EC:4.6.1.1]
114704841  Adcy5; LOW QUALITY PROTEIN: adenylate cyclase type 5 [KO:K08045] [EC:4.6.1.1]
114708522  Adcy6; adenylate cyclase type 6 isoform X1 [KO:K08046] [EC:4.6.1.1]
114708501  Adcy7; LOW QUALITY PROTEIN: adenylate cyclase type 7 [KO:K08047] [EC:4.6.1.1]
114697724  Adcy8; adenylate cyclase type 8 isoform X1 [KO:K08048] [EC:4.6.1.1]
114710615  Adcy9; adenylate cyclase type 9 isoform X1 [KO:K08049] [EC:4.6.1.1]
114684152  Prkaca; cAMP-dependent protein kinase catalytic subunit alpha isoform X1 [KO:K04345] [EC:2.7.11.11]
114698264  Prkacb; cAMP-dependent protein kinase catalytic subunit beta isoform X1 [KO:K04345] [EC:2.7.11.11]
114708288  Gnb1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 [KO:K04536]
114686769  Gnb2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 [KO:K04537]
114708827  Gnb3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 isoform X1 [KO:K07825]
114695341  Gnb4; guanine nucleotide-binding protein subunit beta-4 [KO:K04538]
114690390  Gnb5; guanine nucleotide-binding protein subunit beta-5 [KO:K04539]
114686598  Gng2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 [KO:K07826]
114687039  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2-like [KO:K07826]
114683622  Gng3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 [KO:K04540]
114685202  Gng4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 [KO:K04541]
114698273  Gng5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 [KO:K04542]
114709086  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5-like [KO:K04542]
114688303  Gng7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 [KO:K04543]
114681403  Gng8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 [KO:K04544]
114688340  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10-like [KO:K04545]
114682519  Gng10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 [KO:K04545]
114693442  Gng11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 [KO:K04546]
114687652  Gng14; putative guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-14 [KO:K04347]
114700920  Gng12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 [KO:K04347]
114681254  Gng13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 [KO:K04547]
114693495  Gngt1; guanine nucleotide-binding protein G(T) subunit gamma-T1 [KO:K04548]
114692919  Gngt2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 [KO:K04549]
114698332  Col4a5; collagen alpha-5(IV) chain isoform X1 [KO:K06237]
114698334  Col4a6; collagen alpha-6(IV) chain [KO:K06237]
114695104  Col4a2; collagen alpha-2(IV) chain isoform X1 [KO:K06237]
114695105  Col4a1; collagen alpha-1(IV) chain isoform X1 [KO:K06237]
114696435  Col4a3; collagen alpha-3(IV) chain [KO:K06237]
114696436  Col4a4; collagen alpha-4(IV) chain [KO:K06237]
114698613  Lama2; laminin subunit alpha-2 isoform X1 [KO:K05637]
114704074  Lama1; LOW QUALITY PROTEIN: laminin subunit alpha-1 [KO:K05637]
114704204  Lama5; LOW QUALITY PROTEIN: laminin subunit alpha-5 [KO:K06240]
114698155  Lama3; LOW QUALITY PROTEIN: laminin subunit alpha-3 [KO:K06240]
114696878  Lama4; laminin subunit alpha-4 isoform X1 [KO:K06241]
114708454  Lamb1; laminin subunit beta-1 [KO:K05636]
114705208  Lamb2; LOW QUALITY PROTEIN: laminin subunit beta-2 [KO:K06243]
114702393  Lamb3; laminin subunit beta-3 [KO:K06244]
114703788  Lamc3; laminin subunit gamma-3 [KO:K06247]
114693605  Fn1; LOW QUALITY PROTEIN: fibronectin [KO:K05717]
114703016  Itga2; LOW QUALITY PROTEIN: integrin alpha-2 [KO:K06481]
114702233  Itga2b; LOW QUALITY PROTEIN: integrin alpha-IIb [KO:K06476]
114692904  Itga3; integrin alpha-3 isoform X1 [KO:K06482]
114704479  Itga6; LOW QUALITY PROTEIN: integrin alpha-6 [KO:K06485]
114703598  Itgav; integrin alpha-V isoform X1 [KO:K06487]
114705780  Itgb1; integrin beta-1 isoform X1 [KO:K05719]
114704659  Ptk2; focal adhesion kinase 1 isoform X1 [KO:K05725] [EC:2.7.10.2]
114684032  Pik3cd; LOW QUALITY PROTEIN: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform [KO:K00922] [EC:2.7.1.153]
114693559  Pik3cb; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
114695335  Pik3ca; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
114688966  Pik3r2; phosphatidylinositol 3-kinase regulatory subunit beta isoform X1 [KO:K02649]
114706924  Pik3r3; phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1 [KO:K02649]
114703850  Pik3r1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
114702670  Nkx3-1; homeobox protein Nkx-3.1 [KO:K09348]
114690660  Akt3; RAC-gamma serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
114681524  Akt2; RAC-beta serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
114703046  Akt1; RAC-alpha serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
114706431  Chuk; inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1 [KO:K04467] [EC:2.7.11.10]
114705738  Ikbkb; inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1 [KO:K07209] [EC:2.7.11.10]
114706175  Ikbkg; NF-kappa-B essential modulator isoform X1 [KO:K07210]
114693378  Nfkbia; NF-kappa-B inhibitor alpha [KO:K04734]
114683205  Nfkb1; nuclear factor NF-kappa-B p105 subunit [KO:K02580]
114696755  Nfkb2; nuclear factor NF-kappa-B p100 subunit isoform X1 [KO:K04469]
114682099  Rela; transcription factor p65 [KO:K04735]
114696775  Ptgs2; prostaglandin G/H synthase 2 [KO:K11987] [EC:1.14.99.1]
114691518  Nos2; nitric oxide synthase, inducible [KO:K13241] [EC:1.14.13.39]
114702810  Bcl2; apoptosis regulator Bcl-2 [KO:K02161]
114708003  LOW QUALITY PROTEIN: baculoviral IAP repeat-containing protein 2 [KO:K16060]
114708004  LOW QUALITY PROTEIN: baculoviral IAP repeat-containing protein 3-like [KO:K16060]
114701517  E3 ubiquitin-protein ligase XIAP [KO:K04725] [EC:2.3.2.27]
114704189  Birc7; baculoviral IAP repeat-containing protein 7 isoform X1 [KO:K16061]
114705602  Bcl2l1; bcl-2-like protein 1 [KO:K04570]
114704682  Traf1; TNF receptor-associated factor 1 [KO:K03172]
114692795  Traf2; TNF receptor-associated factor 2 isoform X1 [KO:K03173] [EC:2.3.2.27]
114697589  TNF receptor-associated factor 3-like [KO:K03174]
114703073  Traf3; TNF receptor-associated factor 3 isoform X1 [KO:K03174]
114691489  Traf4; TNF receptor-associated factor 4 [KO:K09848]
114702410  Traf5; TNF receptor-associated factor 5 [KO:K09849]
114710754  Traf6; TNF receptor-associated factor 6 [KO:K03175] [EC:2.3.2.27]
114709670  Mtor; LOW QUALITY PROTEIN: serine/threonine-protein kinase mTOR [KO:K07203] [EC:2.7.11.1]
114685999  Rps6kb2; ribosomal protein S6 kinase beta-2 isoform X1 [KO:K04688] [EC:2.7.11.1]
114699281  Rps6kb1; ribosomal protein S6 kinase beta-1 isoform X1 [KO:K04688] [EC:2.7.11.1]
114680676  Bad; bcl2-associated agonist of cell death isoform X1 [KO:K02158]
114695858  Foxo1; LOW QUALITY PROTEIN: forkhead box protein O1 [KO:K07201]
114693314  Mdm2; E3 ubiquitin-protein ligase Mdm2 isoform X1 [KO:K06643] [EC:2.3.2.27]
114693171  Tp53; cellular tumor antigen p53 [KO:K04451]
114710338  Cdkn1b; cyclin-dependent kinase inhibitor 1B [KO:K06624]
114706157  Cdkn1a; cyclin-dependent kinase inhibitor 1 [KO:K06625]
114696480  Bcr; breakpoint cluster region protein isoform X1 [KO:K08878] [EC:2.7.11.1]
114703784  Abl1; tyrosine-protein kinase ABL1 isoform X1 [KO:K06619] [EC:2.7.10.2]
114691441  Crk; adapter molecule crk isoform X1 [KO:K04438]
114682714  Crkl; crk-like protein [KO:K04438]
119088838  crk-like protein [KO:K04438]
114691162  Cbl; E3 ubiquitin-protein ligase CBL isoform X1 [KO:K04707] [EC:2.3.2.27]
114682811  Stat5a; signal transducer and activator of transcription 5A [KO:K11223]
114682785  LOW QUALITY PROTEIN: signal transducer and activator of transcription 5B [KO:K11224]
114703981  Pim1; serine/threonine-protein kinase pim-1 [KO:K04702] [EC:2.7.11.1]
114701299  Pim2; serine/threonine-protein kinase pim-2 [KO:K08806] [EC:2.7.11.1]
114697109  Kng1; kininogen-1 isoform X1 [KO:K03898]
114692100  Edn1; endothelin-1 [KO:K16366]
114701888  Bdkrb1; LOW QUALITY PROTEIN: B1 bradykinin receptor [KO:K03915]
114701887  Bdkrb2; B2 bradykinin receptor [KO:K03916]
114709202  Ednra; endothelin-1 receptor [KO:K04197]
114690208  Ednrb; endothelin receptor type B [KO:K04198]
114696911  guanine nucleotide-binding protein G(q) subunit alpha [KO:K04634]
114688160  Gna11; guanine nucleotide-binding protein subunit alpha-11 [KO:K04635]
114680674  Plcb3; LOW QUALITY PROTEIN: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 [KO:K05858] [EC:3.1.4.11]
114705921  Plcb2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 [KO:K05858] [EC:3.1.4.11]
114703666  Plcb4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X2 [KO:K05858] [EC:3.1.4.11]
114703672  Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X1 [KO:K05858] [EC:3.1.4.11]
114690439  Prkca; protein kinase C alpha type [KO:K02677] [EC:2.7.11.13]
114692203  Prkcb; protein kinase C beta type isoform X1 [KO:K19662] [EC:2.7.11.13]
114687523  Prkcg; protein kinase C gamma type [KO:K19663] [EC:2.7.11.13]
114707177  Il2; interleukin-2 [KO:K05429]
114700430  interleukin-3-like [KO:K04736]
114681924  Il4; interleukin-4 [KO:K05430]
114689756  Il6; interleukin-6 [KO:K05405]
114707629  Il7; interleukin-7 isoform X1 [KO:K05431]
114691738  Il12a; interleukin-12 subunit alpha [KO:K05406]
114689882  Il12b; interleukin-12 subunit beta [KO:K05425]
114701659  Il15; interleukin-15 isoform X1 [KO:K05433]
114681748  Il23a; interleukin-23 subunit alpha [KO:K05426]
114686767  Epo; erythropoietin [KO:K05437]
114685140  interferon alpha-12-like [KO:K05414]
114685141  interferon alpha-12-like [KO:K05414]
114685144  interferon alpha-12-like [KO:K05414]
114685147  interferon alpha-12-like [KO:K05414]
114685149  interferon alpha-12-like [KO:K05414]
114685150  interferon alpha-12-like [KO:K05414]
114685151  interferon alpha-12-like [KO:K05414]
114685152  interferon alpha-12-like [KO:K05414]
114685154  interferon alpha-12-like [KO:K05414]
114685155  interferon alpha-12-like [KO:K05414]
114688453  interferon alpha-12-like [KO:K05414]
114688454  interferon alpha-12-like [KO:K05414]
114688456  interferon alpha-12-like [KO:K05414]
114688459  interferon alpha-13-like [KO:K05414]
114688460  interferon alpha-12-like [KO:K05414]
114688461  interferon alpha-12-like [KO:K05414]
114688462  interferon alpha-12-like [KO:K05414]
114688463  interferon alpha-12-like [KO:K05414]
114689321  interferon alpha-13-like [KO:K05414]
114689322  interferon alpha-12-like [KO:K05414]
119087415  interferon alpha-3-like [KO:K05414]
119087496  interferon alpha-3-like [KO:K05414]
114698348  interferon alpha-3-like [KO:K05414]
114693330  Ifng; interferon gamma [KO:K04687]
114708790  Il2ra; interleukin-2 receptor subunit alpha [KO:K05068]
114694353  Il2rb; interleukin-2 receptor subunit beta isoform X2 [KO:K05069]
114708654  Il2rg; cytokine receptor common subunit gamma [KO:K05070]
114692223  Il4r; interleukin-4 receptor subunit alpha isoform X1 [KO:K05071]
114694223  Csf2rb; cytokine receptor common subunit beta isoform X3 [KO:K04738]
114694224  cytokine receptor common subunit beta-like [KO:K04738]
114705041  Il5ra; interleukin-5 receptor subunit alpha [KO:K05067]
114707920  Il6r; LOW QUALITY PROTEIN: interleukin-6 receptor subunit alpha [KO:K05055]
114703579  Il6st; LOW QUALITY PROTEIN: interleukin-6 receptor subunit beta [KO:K05060]
114710803  Il7r; interleukin-7 receptor subunit alpha [KO:K05072]
114700924  Il12rb2; LOW QUALITY PROTEIN: interleukin-12 receptor subunit beta-2 [KO:K05064]
114705427  Il13ra1; interleukin-13 receptor subunit alpha-1 [KO:K05076]
114708198  Il15ra; interleukin-15 receptor subunit alpha isoform X1 [KO:K05074]
114700907  Il23r; interleukin-23 receptor [KO:K05065]
114695247  Epor; LOW QUALITY PROTEIN: erythropoietin receptor [KO:K05079]
114698435  Ifnar1; interferon alpha/beta receptor 1 isoform X1 [KO:K05130]
114698437  Ifnar2; LOW QUALITY PROTEIN: interferon alpha/beta receptor 2 [KO:K05131]
114686090  LOW QUALITY PROTEIN: interferon gamma receptor 1 [KO:K05132]
114698434  Ifngr2; interferon gamma receptor 2 isoform X1 [KO:K05133]
114708904  Eml4; LOW QUALITY PROTEIN: echinoderm microtubule-associated protein-like 4 [KO:K15420]
114696211  ALK tyrosine kinase receptor [KO:K05119] [EC:2.7.10.1]
114697520  RAS guanyl-releasing protein 1-like [KO:K04350]
114705910  LOW QUALITY PROTEIN: RAS guanyl-releasing protein 1 [KO:K04350]
114680696  Rasgrp2; RAS guanyl-releasing protein 2 isoform X1 [KO:K12361]
114695916  Rasgrp3; ras guanyl-releasing protein 3 isoform X1 [KO:K12362]
114684979  Rasgrp4; RAS guanyl-releasing protein 4 [KO:K12363]
114693732  Jak1; LOW QUALITY PROTEIN: tyrosine-protein kinase JAK1 [KO:K11217] [EC:2.7.10.2]
114710385  Jak2; tyrosine-protein kinase JAK2 [KO:K04447] [EC:2.7.10.2]
114687957  Jak3; LOW QUALITY PROTEIN: tyrosine-protein kinase JAK3 [KO:K11218] [EC:2.7.10.2]
114682786  Stat3; signal transducer and activator of transcription 3 isoform X1 [KO:K04692]
114705035  Stat1; signal transducer and activator of transcription 1-alpha/beta [KO:K11220]
114681747  Stat2; signal transducer and activator of transcription 2 [KO:K11221]
114705439  Stat4; signal transducer and activator of transcription 4 isoform X1 [KO:K11222]
114704789  Stat6; signal transducer and activator of transcription 6 isoform X1 [KO:K11225]
114705300  Vegfa; vascular endothelial growth factor A isoform X1 [KO:K05448]
114680692  Vegfb; vascular endothelial growth factor B isoform X1 [KO:K16858]
114698087  Pgf; placenta growth factor isoform X1 [KO:K16859]
114683909  Vegfc; vascular endothelial growth factor C [KO:K05449]
114705711  Vegfd; vascular endothelial growth factor D isoform X1 [KO:K05449]
114680857  Tgfa; protransforming growth factor alpha isoform X1 [KO:K08774]
114682692  Egf; pro-epidermal growth factor [KO:K04357]
114705532  Egfr; epidermal growth factor receptor isoform X1 [KO:K04361] [EC:2.7.10.1]
114706940  Erbb2; receptor tyrosine-protein kinase erbB-2 [KO:K05083] [EC:2.7.10.1]
114682214  Pdgfa; platelet-derived growth factor subunit A [KO:K04359]
114694276  Pdgfb; platelet-derived growth factor subunit B isoform X1 [KO:K17386]
114683759  Pdgfra; platelet-derived growth factor receptor alpha isoform X1 [KO:K04363] [EC:2.7.10.1]
114707365  Pdgfrb; LOW QUALITY PROTEIN: platelet-derived growth factor receptor beta [KO:K05089] [EC:2.7.10.1]
114700619  Igf1; insulin-like growth factor I isoform X2 [KO:K05459]
114694075  insulin-like growth factor II isoform X3 [KO:K13769]
114695462  Igf1r; insulin-like growth factor 1 receptor [KO:K05087] [EC:2.7.10.1]
114707287  Kitlg; kit ligand isoform X1 [KO:K05461]
114683608  Kit; mast/stem cell growth factor receptor Kit isoform X1 [KO:K05091] [EC:2.7.10.1]
114687177  Flt3lg; fms-related tyrosine kinase 3 ligand isoform X2 [KO:K05454]
114699133  Flt3; receptor-type tyrosine-protein kinase FLT3 isoform X1 [KO:K05092] [EC:2.7.10.1]
114687327  Hgf; LOW QUALITY PROTEIN: hepatocyte growth factor [KO:K05460]
114694721  Met; hepatocyte growth factor receptor isoform X1 [KO:K05099] [EC:2.7.10.1]
114708354  Fgf1; fibroblast growth factor 1 isoform X1 [KO:K18496]
114707170  Fgf2; fibroblast growth factor 2 isoform X1 [KO:K18497]
114683479  Fgf18; fibroblast growth factor 18 [KO:K04358]
114684105  Fgf22; fibroblast growth factor 22 isoform X1 [KO:K04358]
114704240  Fgf10; fibroblast growth factor 10 [KO:K04358]
114704897  Fgf16; fibroblast growth factor 16 [KO:K04358]
114698782  Fgf17; fibroblast growth factor 17 [KO:K04358]
114693842  Fgf9; fibroblast growth factor 9 [KO:K04358]
114708136  Fgf8; fibroblast growth factor 8 isoform X2 [KO:K04358]
114701407  Fgf6; fibroblast growth factor 6 [KO:K04358]
114695166  Fgf20; fibroblast growth factor 20 [KO:K04358]
114695227  Fgf3; fibroblast growth factor 3 [KO:K04358]
114695229  Fgf4; fibroblast growth factor 4 [KO:K04358]
114695719  Fgf5; fibroblast growth factor 5 isoform X1 [KO:K04358]
114709068  Fgf7; fibroblast growth factor 7 [KO:K04358]
114695237  Fgf19; fibroblast growth factor 19 [KO:K22603]
114684727  Fgf21; fibroblast growth factor 21 [KO:K22429]
114701473  Fgf23; fibroblast growth factor 23 [KO:K22428]
114681341  Fgfr1; fibroblast growth factor receptor 1 isoform X4 [KO:K04362] [EC:2.7.10.1]
114692385  Fgfr2; fibroblast growth factor receptor 2 isoform X2 [KO:K05093] [EC:2.7.10.1]
114694056  Fgfr3; fibroblast growth factor receptor 3 isoform X4 [KO:K05094] [EC:2.7.10.1]
114689359  Fgfr4; fibroblast growth factor receptor 4 [KO:K05095] [EC:2.7.10.1]
114707024  Grb2; growth factor receptor-bound protein 2 [KO:K04364]
114684224  Sos2; son of sevenless homolog 2 isoform X1 [KO:K03099]
114681621  Sos1; son of sevenless homolog 1 [KO:K03099]
114685127  GTPase HRas-like [KO:K02833]
114688488  GTPase HRas-like [KO:K02833]
114693493  GTPase HRas-like [KO:K02833]
114693595  Hras; GTPase HRas isoform X1 [KO:K02833]
114696553  GTPase HRas-like [KO:K02833]
114708477  Kras; GTPase KRas isoform X2 [KO:K07827]
114698582  Nras; GTPase NRas [KO:K07828]
114703900  Araf; serine/threonine-protein kinase A-Raf isoform X2 [KO:K08845] [EC:2.7.11.1]
114706830  Braf; LOW QUALITY PROTEIN: serine/threonine-protein kinase B-raf [KO:K04365] [EC:2.7.11.1]
114689636  Raf1; RAF proto-oncogene serine/threonine-protein kinase isoform X1 [KO:K04366] [EC:2.7.11.1]
114691497  Map2k1; dual specificity mitogen-activated protein kinase kinase 1 isoform X2 [KO:K04368] [EC:2.7.12.2]
114688121  Map2k2; dual specificity mitogen-activated protein kinase kinase 2 [KO:K04369] [EC:2.7.12.2]
114682732  Mapk1; mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
114704332  Mapk3; mitogen-activated protein kinase 3 [KO:K04371] [EC:2.7.11.24]
114710523  mitogen-activated protein kinase 1-like [KO:K04371] [EC:2.7.11.24]
114693768  Jun; transcription factor AP-1 [KO:K04448]
114698038  Fos; proto-oncogene c-Fos [KO:K04379]
114699780  Ets1; protein C-ets-1 isoform X1 [KO:K02678]
114708012  Mmp1; interstitial collagenase [KO:K01388] [EC:3.4.24.7]
114694533  Mmp2; LOW QUALITY PROTEIN: 72 kDa type IV collagenase [KO:K01398] [EC:3.4.24.24]
114692635  Mmp9; matrix metalloproteinase-9 [KO:K01403] [EC:3.4.24.35]
114704814  Cdk4; cyclin-dependent kinase 4 [KO:K02089] [EC:2.7.11.22]
114705023  Rps6ka5; ribosomal protein S6 kinase alpha-5 isoform X1 [KO:K04445] [EC:2.7.11.1]
114689662  Ret; proto-oncogene tyrosine-protein kinase receptor Ret [KO:K05126] [EC:2.7.10.1]
114698535  Ccdc6; LOW QUALITY PROTEIN: coiled-coil domain-containing protein 6 [KO:K09288]
114699359  Ncoa4; nuclear receptor coactivator 4 isoform X1 [KO:K09289]
114683361  Ntrk1; high affinity nerve growth factor receptor isoform X1 [KO:K03176] [EC:2.7.10.1]
114707877  Tpm3; tropomyosin alpha-3 chain isoform X12 [KO:K09290]
114696778  Tpr; LOW QUALITY PROTEIN: nucleoprotein TPR [KO:K09291]
114691932  Tfg; protein TFG isoform X1 [KO:K09292]
114710959  Rassf1; ras association domain-containing protein 1 isoform X1 [KO:K09850]
114698056  Rassf5; LOW QUALITY PROTEIN: ras association domain-containing protein 5 [KO:K08015]
114692609  Stk4; serine/threonine-protein kinase 4 isoform X1 [KO:K04411]
114691151  Dapk2; death-associated protein kinase 2 isoform X1 [KO:K08803] [EC:2.7.11.1]
114688122  Dapk3; death-associated protein kinase 3 isoform X1 [KO:K08803] [EC:2.7.11.1]
114709708  Dapk1; death-associated protein kinase 1 [KO:K08803] [EC:2.7.11.1]
114692579  Plcg1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [KO:K01116] [EC:3.1.4.11]
114697457  Plcg2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 [KO:K05859] [EC:3.1.4.11]
114703932  Elk1; ETS domain-containing protein Elk-1 isoform X2 [KO:K04375]
114691640  Calml4; calmodulin-like protein 4 isoform X2 [KO:K02183]
114681418  Calm3; calmodulin-3 [KO:K02183]
114705020  Calm1; calmodulin-1 [KO:K02183]
114708260  Calml6; LOW QUALITY PROTEIN: calmodulin-like protein 6 [KO:K02183]
114708768  calmodulin-4-like [KO:K02183]
114708779  Calml3; calmodulin-like protein 3 [KO:K02183]
114709209  Calm2; calmodulin-2 [KO:K02183]
114682227  Camk2d; calcium/calmodulin-dependent protein kinase type II subunit delta isoform X1 [KO:K04515] [EC:2.7.11.17]
114700207  Camk2g; calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X1 [KO:K04515] [EC:2.7.11.17]
114693978  Camk2b; calcium/calmodulin-dependent protein kinase type II subunit beta isoform X7 [KO:K04515] [EC:2.7.11.17]
114707396  Camk2a; LOW QUALITY PROTEIN: calcium/calmodulin-dependent protein kinase type II subunit alpha [KO:K04515] [EC:2.7.11.17]
114702785  Ralgds; ral guanine nucleotide dissociation stimulator isoform X1 [KO:K08732]
114685433  Rala; ras-related protein Ral-A [KO:K07834]
114680725  ras-related protein Ral-B [KO:K07835]
114700234  Ralb; ras-related protein Ral-B [KO:K07835]
114696319  Ralbp1; ralA-binding protein 1 [KO:K08773]
114691309  cell division control protein 42 homolog [KO:K04393]
114697206  Cdc42; cell division control protein 42 homolog isoform X1 [KO:K04393]
114701275  cell division control protein 42 homolog [KO:K04393]
114707535  Rac1; ras-related C3 botulinum toxin substrate 1 isoform X1 [KO:K04392]
114694231  Rac2; ras-related C3 botulinum toxin substrate 2 [KO:K07860]
114680645  Rac3; ras-related C3 botulinum toxin substrate 3 isoform X1 [KO:K07861]
114687550  Pld2; phospholipase D2 [KO:K01115] [EC:3.1.4.4]
114697539  Pld1; phospholipase D1 [KO:K01115] [EC:3.1.4.4]
114691777  Mapk10; mitogen-activated protein kinase 10 isoform X1 [KO:K04440] [EC:2.7.11.24]
114681520  Mapk9; mitogen-activated protein kinase 9 isoform X1 [KO:K04440] [EC:2.7.11.24]
114699348  Mapk8; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
114692753  Pax8; paired box protein Pax-8 isoform X2 [KO:K09293]
114689632  Pparg; peroxisome proliferator-activated receptor gamma isoform X1 [KO:K08530]
114702794  Rxra; retinoic acid receptor RXR-alpha [KO:K08524]
114686359  Rxrb; retinoic acid receptor RXR-beta isoform X1 [KO:K08525]
114689910  Rxrg; retinoic acid receptor RXR-gamma isoform X1 [KO:K08526]
114697419  Rarb; retinoic acid receptor beta isoform X1 [KO:K08528]
114707480  Esr1; estrogen receptor [KO:K08550]
114697733  Esr2; estrogen receptor beta [KO:K08551]
114697171  Ncoa1; nuclear receptor coactivator 1 isoform X1 [KO:K09101] [EC:2.3.1.48]
114692649  Ncoa3; nuclear receptor coactivator 3 isoform X1 [KO:K11256] [EC:2.3.1.48]
114696625  Sp1; transcription factor Sp1 isoform X1 [KO:K04684]
114706127  Ppard; peroxisome proliferator-activated receptor delta [KO:K04504]
114687697  junction plakoglobin [KO:K10056]
114690231  Zbtb16; zinc finger and BTB domain-containing protein 16 [KO:K10055]
114706921  Rara; retinoic acid receptor alpha isoform X1 [KO:K08527]
114707180  Ccna2; cyclin-A2 [KO:K06627]
114695883  Ccna1; cyclin-A1 [KO:K06627]
114708922  Pml; protein PML isoform X1 [KO:K10054] [EC:2.3.2.-]
114698416  Runx1; runt-related transcription factor 1 isoform X1 [KO:K08367]
114694589  Runx1t1; protein CBFA2T1 isoform X1 [KO:K10053]
114699680  Spi1; transcription factor PU.1 isoform X2 [KO:K09438]
114698911  Cebpa; CCAAT/enhancer-binding protein alpha [KO:K09055]
114682475  granulocyte-macrophage colony-stimulating factor receptor subunit alpha-like isoform X1 [KO:K05066]
114704288  Csf3r; granulocyte colony-stimulating factor receptor isoform X2 [KO:K05061]
114707382  Csf1r; macrophage colony-stimulating factor 1 receptor [KO:K05090] [EC:2.7.10.1]
114698355  LOW QUALITY PROTEIN: cyclin-dependent kinase inhibitor 2A-like [KO:K06621]
114706553  E2f1; LOW QUALITY PROTEIN: transcription factor E2F1 [KO:K17454]
114697224  E2f2; transcription factor E2F2 isoform X1 [KO:K09389]
114701050  E2f3; transcription factor E2F3 isoform X1 [KO:K06620]
114697754  Max; protein max isoform X1 [KO:K04453]
114700870  Zbtb17; LOW QUALITY PROTEIN: zinc finger and BTB domain-containing protein 17 [KO:K10500]
114698354  cyclin-dependent kinase 4 inhibitor B [KO:K04685]
114688249  Cdk6; cyclin-dependent kinase 6 [KO:K02091] [EC:2.7.11.22]
114701440  Ccnd2; G1/S-specific cyclin-D2 [KO:K10151]
114705331  Ccnd3; G1/S-specific cyclin-D3 isoform X1 [KO:K10152]
114689487  Cks2; cyclin-dependent kinases regulatory subunit 2 [KO:K02219]
114707947  Cks1b; cyclin-dependent kinases regulatory subunit 1 isoform X1 [KO:K02219]
114683050  Skp1; S-phase kinase-associated protein 1 [KO:K03094]
114699340  S-phase kinase-associated protein 1-like [KO:K03094]
114698005  Cul1; cullin-1 [KO:K03347]
114707186  E3 ubiquitin-protein ligase RBX1-like [KO:K03868] [EC:2.3.2.32]
114694298  Rbx1; E3 ubiquitin-protein ligase RBX1 [KO:K03868] [EC:2.3.2.32]
114681382  S-phase kinase-associated protein 2-like [KO:K03875]
114697360  Skp2; S-phase kinase-associated protein 2 isoform X1 [KO:K03875]
114681779  Cdk2; cyclin-dependent kinase 2 isoform X1 [KO:K02206] [EC:2.7.11.22]
114698889  Ccne1; G1/S-specific cyclin-E1 isoform X1 [KO:K06626]
114694576  Ccne2; G1/S-specific cyclin-E2 isoform X1 [KO:K06626]
114698792  Rb1; retinoblastoma-associated protein isoform X1 [KO:K06618]
114688301  Gadd45b; growth arrest and DNA damage-inducible protein GADD45 beta [KO:K04402]
114689482  Gadd45g; growth arrest and DNA damage-inducible protein GADD45 gamma [KO:K04402]
114700921  Gadd45a; growth arrest and DNA damage-inducible protein GADD45 alpha [KO:K04402]
114684640  Bax; apoptosis regulator BAX isoform X1 [KO:K02159]
114706143  Bak1; bcl-2 homologous antagonist/killer isoform X1 [KO:K14021]
114699687  Ddb2; DNA damage-binding protein 2 [KO:K10140]
114694653  Polk; DNA polymerase kappa isoform X1 [KO:K03511] [EC:2.7.7.7]
114696103  Tert; telomerase reverse transcriptase isoform X1 [KO:K11126] [EC:2.7.7.49]
114681846  LOW QUALITY PROTEIN: microphthalmia-associated transcription factor-like [KO:K09455]
114695379  Mitf; microphthalmia-associated transcription factor isoform X1 [KO:K09455]
114685302  Tgfb1; transforming growth factor beta-1 proprotein [KO:K13375]
114698210  Tgfb2; transforming growth factor beta-2 proprotein isoform X1 [KO:K13376]
114697904  Tgfb3; transforming growth factor beta-3 proprotein [KO:K13377]
114691745  LOW QUALITY PROTEIN: TGF-beta receptor type-1-like [KO:K04674] [EC:2.7.11.30]
114690920  TGF-beta receptor type-1-like [KO:K04674] [EC:2.7.11.30]
114702344  Tgfbr1; TGF-beta receptor type-1 isoform X1 [KO:K04674] [EC:2.7.11.30]
114704977  Tgfbr2; TGF-beta receptor type-2 isoform X1 [KO:K04388] [EC:2.7.11.30]
114694883  Smad2; mothers against decapentaplegic homolog 2 [KO:K04500]
114691539  Smad3; mothers against decapentaplegic homolog 3 [KO:K23605]
114690183  Smad4; mothers against decapentaplegic homolog 4 isoform X1 [KO:K04501]
114695325  Mecom; histone-lysine N-methyltransferase MECOM isoform X1 [KO:K04462] [EC:2.1.1.367]
114692755  Ctbp2; C-terminal-binding protein 2 isoform X1 [KO:K04496] [EC:1.1.1.428]
114694049  Ctbp1; C-terminal-binding protein 1 isoform X1 [KO:K04496] [EC:1.1.1.428]
114683075  histone deacetylase 1-like [KO:K06067] [EC:3.5.1.98]
114705645  Hdac1; histone deacetylase 1 [KO:K06067] [EC:3.5.1.98]
114696875  Hdac2; histone deacetylase 2 [KO:K06067] [EC:3.5.1.98]
114685379  Mlh1; DNA mismatch repair protein Mlh1 isoform X1 [KO:K08734]
114695418  DNA mismatch repair protein Msh2 [KO:K08735]
114709214  Msh2; DNA mismatch repair protein Msh2 isoform X1 [KO:K08735]
114708052  Msh3; DNA mismatch repair protein Msh3 isoform X1 [KO:K08736]
114709246  Msh6; DNA mismatch repair protein Msh6 [KO:K08737]
114699159  Brca2; LOW QUALITY PROTEIN: breast cancer type 2 susceptibility protein [KO:K08775]
114704631  Rad51; DNA repair protein RAD51 homolog 1 [KO:K04482]
114689971  Faslg; tumor necrosis factor ligand superfamily member 6 isoform X1 [KO:K04389]
114694438  Fadd; FAS-associated death domain protein [KO:K02373]
114704437  Casp8; caspase-8 [KO:K04398] [EC:3.4.22.61]
114700736  Bid; BH3-interacting domain death agonist [KO:K04726]
114685740  Pmaip1; phorbol-12-myristate-13-acetate-induced protein 1 isoform X1 [KO:K10131]
114681446  Bbc3; bcl-2-binding component 3 isoform X1 [KO:K10132]
114709516  Bcl2l11; LOW QUALITY PROTEIN: bcl-2-like protein 11 [KO:K16341]
114689745  cytochrome c, somatic [KO:K08738]
114697928  cytochrome c-like [KO:K08738]
114693819  cytochrome c, somatic-like [KO:K08738]
114700813  cytochrome c, testis-specific [KO:K08738]
114695408  cytochrome c, somatic-like [KO:K08738]
114709020  cytochrome c, somatic-like [KO:K08738]
114703574  cytochrome c, somatic-like [KO:K08738]
114710287  cytochrome c, somatic-like [KO:K08738]
114700550  Apaf1; apoptotic protease-activating factor 1 isoform X1 [KO:K02084]
114697063  Casp7; caspase-7 isoform X1 [KO:K04397] [EC:3.4.22.60]
114695216  Keap1; LOW QUALITY PROTEIN: kelch-like ECH-associated protein 1 [KO:K10456]
114700818  Nfe2l2; nuclear factor erythroid 2-related factor 2 isoform X1 [KO:K05638]
114681400  Hmox1; heme oxygenase 1 [KO:K00510] [EC:1.14.14.18]
114706734  Nqo1; NAD(P)H dehydrogenase [quinone] 1 [KO:K00355] [EC:1.6.5.2]
114686535  glutathione S-transferase Mu 1-like [KO:K00799] [EC:2.5.1.18]
114686793  glutathione S-transferase A2-like isoform X1 [KO:K00799] [EC:2.5.1.18]
114686794  glutathione S-transferase A2-like [KO:K00799] [EC:2.5.1.18]
114686795  glutathione S-transferase alpha-1-like [KO:K00799] [EC:2.5.1.18]
114686796  glutathione S-transferase A2-like [KO:K00799] [EC:2.5.1.18]
114686797  glutathione S-transferase A2-like [KO:K00799] [EC:2.5.1.18]
114686798  glutathione S-transferase A2 [KO:K00799] [EC:2.5.1.18]
114687986  glutathione S-transferase alpha-4-like [KO:K00799] [EC:2.5.1.18]
114689912  Mgst3; microsomal glutathione S-transferase 3 [KO:K00799] [EC:2.5.1.18]
114692337  glutathione S-transferase A6 [KO:K00799] [EC:2.5.1.18]
114692338  glutathione S-transferase alpha-3 [KO:K00799] [EC:2.5.1.18]
114692339  glutathione S-transferase alpha-5 [KO:K00799] [EC:2.5.1.18]
114692342  glutathione S-transferase-like [KO:K00799] [EC:2.5.1.18]
114692343  glutathione S-transferase alpha-3-like isoform X1 [KO:K00799] [EC:2.5.1.18]
114699990  glutathione S-transferase Mu 7 isoform X2 [KO:K00799] [EC:2.5.1.18]
114699991  glutathione S-transferase Mu 1 [KO:K00799] [EC:2.5.1.18]
114699992  glutathione S-transferase Mu 2 [KO:K00799] [EC:2.5.1.18]
114699993  glutathione S-transferase Mu 6 [KO:K00799] [EC:2.5.1.18]
114699994  glutathione S-transferase Mu 1-like [KO:K00799] [EC:2.5.1.18]
114699995  glutathione S-transferase Mu 2-like isoform X1 [KO:K00799] [EC:2.5.1.18]
114699996  glutathione S-transferase Mu 1 [KO:K00799] [EC:2.5.1.18]
114699997  glutathione S-transferase Mu 3 [KO:K00799] [EC:2.5.1.18]
114699999  Gstm3; glutathione S-transferase Mu 3 [KO:K00799] [EC:2.5.1.18]
114695037  Mgst1; microsomal glutathione S-transferase 1 [KO:K00799] [EC:2.5.1.18]
114695881  Mgst2; microsomal glutathione S-transferase 2 [KO:K00799] [EC:2.5.1.18]
114696494  glutathione S-transferase theta-3 [KO:K00799] [EC:2.5.1.18]
114696495  glutathione S-transferase theta-1 isoform X1 [KO:K00799] [EC:2.5.1.18]
114696497  glutathione S-transferase theta-4 [KO:K00799] [EC:2.5.1.18]
114696498  glutathione S-transferase theta-2 [KO:K00799] [EC:2.5.1.18]
114696706  glutathione S-transferase omega-2 [KO:K00799] [EC:2.5.1.18]
114696723  glutathione S-transferase omega-1-like [KO:K00799] [EC:2.5.1.18]
114694764  glutathione S-transferase P [KO:K23790] [EC:2.5.1.18]
114694770  glutathione S-transferase P-like isoform X1 [KO:K23790] [EC:2.5.1.18]
114681001  Txnrd2; thioredoxin reductase 2, mitochondrial isoform X1 [KO:K22182] [EC:1.8.1.9]
114681124  Txnrd3; thioredoxin reductase 3 [KO:K22182] [EC:1.8.1.9]
114700608  Txnrd1; thioredoxin reductase 1, cytoplasmic isoform X1 [KO:K22182] [EC:1.8.1.9]
114689616  Vhl; von Hippel-Lindau disease tumor suppressor [KO:K03871]
119086770  von Hippel-Lindau disease tumor suppressor-like [KO:K03871]
114683462  elongin-C-like [KO:K03872]
114690123  Eloc; elongin-C [KO:K03872]
114692175  elongin-C-like [KO:K03872]
114684495  elongin-B-like [KO:K03873]
114680792  Elob; elongin-B [KO:K03873]
114688345  elongin-B-like [KO:K03873]
114689282  elongin-B-like [KO:K03873]
114692290  LOW QUALITY PROTEIN: elongin-B-like [KO:K03873]
114701918  elongin-B-like [KO:K03873]
114681532  Egln2; prolyl hydroxylase EGLN2 isoform X1 [KO:K09592] [EC:1.14.11.29]
114689778  egl nine homolog 1-like [KO:K09592] [EC:1.14.11.29]
114704866  LOW QUALITY PROTEIN: egl nine homolog 1-like [KO:K09592] [EC:1.14.11.29]
114693363  Egln3; LOW QUALITY PROTEIN: prolyl hydroxylase EGLN3 [KO:K09592] [EC:1.14.11.29]
114707163  Egln1; LOW QUALITY PROTEIN: egl nine homolog 1 [KO:K09592] [EC:1.14.11.29]
114690666  Fh; fumarate hydratase, mitochondrial [KO:K01679] [EC:4.2.1.2]
114683746  Hif1a; hypoxia-inducible factor 1-alpha isoform X1 [KO:K08268]
114709101  Epas1; endothelial PAS domain-containing protein 1 [KO:K09095]
114682408  Arnt; aryl hydrocarbon receptor nuclear translocator isoform X1 [KO:K09097]
114696236  Arnt2; aryl hydrocarbon receptor nuclear translocator 2 isoform X1 [KO:K15589]
114694299  Ep300; histone acetyltransferase p300 isoform X1 [KO:K04498] [EC:2.3.1.48]
114710614  CREB-binding protein isoform X1 [KO:K04498] [EC:2.3.1.48]
114704945  Slc2a1; solute carrier family 2, facilitated glucose transporter member 1 isoform X1 [KO:K07299]
114702976  Jag1; protein jagged-1 [KO:K06052]
114703037  Jag2; protein jagged-2 isoform X1 [KO:K21635]
114691330  Dll1; delta-like protein 1 [KO:K06051]
114684632  Dll3; LOW QUALITY PROTEIN: delta-like protein 3 [KO:K06051]
114704625  Dll4; delta-like protein 4 [KO:K06051]
114692821  Notch1; LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 1 [KO:K02599]
114686260  Notch2; LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 2 [KO:K20994]
114686138  Notch3; LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 3 [KO:K20995]
114705807  Notch4; neurogenic locus notch homolog protein 4 [KO:K20996]
114707351  Hes1; transcription factor HES-1 [KO:K06054]
114708255  Hes5; transcription factor HES-5 [KO:K06055]
114681158  Heyl; LOW QUALITY PROTEIN: hairy/enhancer-of-split related with YRPW motif-like protein [KO:K09091]
114692533  Hey2; hairy/enhancer-of-split related with YRPW motif protein 2 [KO:K09091]
114707632  Hey1; hairy/enhancer-of-split related with YRPW motif protein 1 [KO:K09091]
114681497  Flt4; LOW QUALITY PROTEIN: vascular endothelial growth factor receptor 3 [KO:K05097] [EC:2.7.10.1]
114689766  Shh; sonic hedgehog protein [KO:K11988]
114708424  Ptch1; protein patched homolog 1 isoform X1 [KO:K06225]
114691077  Smo; smoothened homolog [KO:K06226]
114696170  Kif7; kinesin-like protein KIF7 isoform X4 [KO:K18806]
114696750  Sufu; suppressor of fused homolog isoform X3 [KO:K06229]
114704826  Gli1; zinc finger protein GLI1 [KO:K16797]
114700236  Gli2; zinc finger protein GLI2 [KO:K16798]
114685370  Gli3; transcriptional activator GLI3 isoform X2 [KO:K06230]
114699539  Bmp2; bone morphogenetic protein 2 isoform X1 [KO:K21283]
114696047  Bmp4; bone morphogenetic protein 4 [KO:K04662]
114701622  hedgehog-interacting protein [KO:K06231]
114709388  Ptch2; LOW QUALITY PROTEIN: protein patched homolog 2 [KO:K11101]
114703161  Ar; androgen receptor [KO:K08557]
114691694  heat shock protein HSP 90-alpha-like [KO:K04079]
114686218  heat shock protein HSP 90-alpha-like [KO:K04079]
114707842  Hsp90ab1; heat shock protein HSP 90-beta [KO:K04079]
114703084  Hsp90aa1; heat shock protein HSP 90-alpha [KO:K04079]
114700616  Hsp90b1; endoplasmin [KO:K09487]
114695777  LOW QUALITY PROTEIN: endoplasmin-like [KO:K09487]
Compound
C00027  Hydrogen peroxide
C00039  DNA
C00076  Calcium cation
C00122  Fumarate
C00149  (S)-Malate
C00165  Diacylglycerol
C00187  Cholesterol
C00280  Androstenedione
C00410  Progesterone
C00416  Phosphatidate
C00533  Nitric oxide
C00535  Testosterone
C00575  3',5'-Cyclic AMP
C00584  Prostaglandin E2
C00681  1-Acyl-sn-glycerol 3-phosphate
C00704  Superoxide
C00735  Cortisol
C00762  Cortisone
C00777  Retinoate
C00951  Estradiol-17beta
C01227  Dehydroepiandrosterone
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01471  Acrolein
C03917  Dihydrotestosterone
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C07653  Flutamide
C15493  9-cis-Retinoic acid
C16038  2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
C16844  Hydroxyl radical
C21641  Hydroperoxyl radical
C21642  4-Hydroxynonenal
Reference
  Authors
Weinberg RA.
  Title
The biology of cancer
  Journal
Garland Science, Taylor & Francis Group, LLC (2007)
Reference
PMID:10647931
  Authors
Hanahan D, Weinberg RA
  Title
The hallmarks of cancer.
  Journal
Cell 100:57-70 (2000)
DOI:10.1016/S0092-8674(00)81683-9
Reference
PMID:15000146
  Authors
Grady WM.
  Title
Genomic instability and colon cancer.
  Journal
Cancer Metastasis Rev 23:11-27 (2004)
DOI:10.1023/A:1025861527711
Reference
PMID:16555243
  Authors
Soreide K, Janssen EA, Soiland H, Korner H, Baak JP.
  Title
Microsatellite instability in colorectal cancer.
  Journal
Br J Surg 93:395-406 (2006)
DOI:10.1002/bjs.5328
Reference
PMID:11078609
  Authors
Anwar S, Hall C, White J, Deakin M, Farrell W, Elder JB.
  Title
Hereditary non-polyposis colorectal cancer: an updated review.
  Journal
Eur J Surg Oncol 26:635-45 (2000)
DOI:10.1053/ejso.2000.0974
Reference
PMID:16699851
  Authors
Takayama T, Miyanishi K, Hayashi T, Sato Y, Niitsu Y.
  Title
Colorectal cancer: genetics of development and metastasis.
  Journal
J Gastroenterol 41:185-92 (2006)
DOI:10.1007/s00535-006-1801-6
Reference
PMID:12621137
  Authors
Lynch HT, de la Chapelle A.
  Title
Hereditary colorectal cancer.
  Journal
N Engl J Med 348:919-32 (2003)
DOI:10.1056/NEJMra012242
Reference
PMID:12951588
  Authors
Rajagopalan H, Nowak MA, Vogelstein B, Lengauer C.
  Title
The significance of unstable chromosomes in colorectal cancer.
  Journal
Nat Rev Cancer 3:695-701 (2003)
DOI:10.1038/nrc1165
Reference
PMID:10505543
  Authors
Behrens J.
  Title
Cadherins and catenins: role in signal transduction and tumor progression.
  Journal
Cancer Metastasis Rev 18:15-30 (1999)
DOI:10.1023/A:1006200102166
Reference
PMID:16042571
  Authors
Behrens J.
  Title
The role of the Wnt signalling pathway in colorectal tumorigenesis.
  Journal
Biochem Soc Trans 33:672-5 (2005)
DOI:10.1042/BST0330672
Reference
PMID:15349822
  Authors
Behrens J, Lustig B.
  Title
The Wnt connection to tumorigenesis.
  Journal
Int J Dev Biol 48:477-87 (2004)
DOI:10.1387/ijdb.041815jb
Reference
PMID:9196022
  Authors
Polakis P.
  Title
The adenomatous polyposis coli (APC) tumor suppressor.
  Journal
Biochim Biophys Acta 1332:F127-47 (1997)
DOI:10.1016/S0304-419X(97)00008-5
Reference
PMID:12737309
  Authors
Janssen KP.
  Title
Murine models of colorectal cancer: studying the role of oncogenic K-ras.
  Journal
Cell Mol Life Sci 60:495-506 (2003)
DOI:10.1007/s000180300041
Reference
PMID:11459867
  Authors
Adjei AA.
  Title
Blocking oncogenic Ras signaling for cancer therapy.
  Journal
J Natl Cancer Inst 93:1062-74 (2001)
DOI:10.1093/jnci/93.14.1062
Reference
PMID:15573119
  Authors
Arakawa H.
  Title
Netrin-1 and its receptors in tumorigenesis.
  Journal
Nat Rev Cancer 4:978-87 (2004)
DOI:10.1038/nrc1504
Reference
PMID:15310786
  Authors
Mehlen P, Fearon ER.
  Title
Role of the dependence receptor DCC in colorectal cancer pathogenesis.
  Journal
J Clin Oncol 22:3420-8 (2004)
DOI:10.1200/JCO.2004.02.019
Reference
PMID:11223406
  Authors
Peltomaki P.
  Title
DNA mismatch repair and cancer.
  Journal
Mutat Res 488:77-85 (2001)
DOI:10.1016/S1383-5742(00)00058-2
Reference
PMID:15711891
  Authors
Li F, Cao Y, Townsend CM Jr, Ko TC.
  Title
TGF-beta signaling in colon cancer cells.
  Journal
World J Surg 29:306-11 (2005)
DOI:10.1007/s00268-004-7813-6
Reference
PMID:11170304
  Authors
Roman C, Saha D, Beauchamp R.
  Title
TGF-beta and colorectal carcinogenesis.
  Journal
Microsc Res Tech 52:450-7 (2001)
DOI:10.1002/1097-0029(20010215)52:4<450::AID-JEMT1030>3.0.CO;2-O
Reference
PMID:16326109
  Authors
Watson AJ.
  Title
An overview of apoptosis and the prevention of colorectal cancer.
  Journal
Crit Rev Oncol Hematol 57:107-21 (2006)
DOI:10.1016/j.critrevonc.2005.06.005
Reference
PMID:15479695
  Authors
Watson AJ.
  Title
Apoptosis and colorectal cancer.
  Journal
Gut 53:1701-9 (2004)
DOI:10.1136/gut.2004.052704
Reference
PMID:11477132
  Authors
Houlston RS.
  Title
What we could do now: molecular pathology of colorectal cancer.
  Journal
Mol Pathol 54:206-14 (2001)
DOI:10.1136/mp.54.4.206
Reference
  Authors
Von Hoff D, Evans D, Hruban R (ed).
  Title
Pancreatic cancer
  Journal
Jones and Bartlett publishers (2005)
Reference
  Authors
Niitsu Y, Yokota J (ed).
  Title
[Oncogenes and Tumor Suppressor Genes for Medical Oncologist] (In Japanese)
  Journal
Nankodo (1999)
Reference
PMID:12459728
  Authors
Bardeesy N, DePinho RA.
  Title
Pancreatic cancer biology and genetics.
  Journal
Nat Rev Cancer 2:897-909 (2002)
DOI:10.1038/nrc949
Reference
PMID:11407945
  Authors
Bardeesy N, Sharpless NE, DePinho RA, Merlino G.
  Title
The genetics of pancreatic adenocarcinoma: a roadmap for a mouse model.
  Journal
Semin Cancer Biol 11:201-18 (2001)
DOI:10.1006/scbi.2000.0371
Reference
PMID:12946833
  Authors
Cowgill SM, Muscarella P.
  Title
The genetics of pancreatic cancer.
  Journal
Am J Surg 186:279-86 (2003)
DOI:10.1016/S0002-9610(03)00226-5
Reference
PMID:16702400
  Authors
Hezel AF, Kimmelman AC, Stanger BZ, Bardeesy N, Depinho RA.
  Title
Genetics and biology of pancreatic ductal adenocarcinoma.
  Journal
Genes Dev 20:1218-49 (2006)
DOI:10.1101/gad.1415606
Reference
PMID:10740269
  Authors
Shields JM, Pruitt K, McFall A, Shaub A, Der CJ.
  Title
Understanding Ras: 'it ain't over 'til it's over'.
  Journal
Trends Cell Biol 10:147-54 (2000)
DOI:10.1016/S0962-8924(00)01740-2
Reference
PMID:12648469
  Authors
Holbro T, Civenni G, Hynes NE.
  Title
The ErbB receptors and their role in cancer progression.
  Journal
Exp Cell Res 284:99-110 (2003)
DOI:10.1016/S0014-4827(02)00099-X
Reference
PMID:14967450
  Authors
Marmor MD, Skaria KB, Yarden Y.
  Title
Signal transduction and oncogenesis by ErbB/HER receptors.
  Journal
Int J Radiat Oncol Biol Phys 58:903-13 (2004)
DOI:10.1016/j.ijrobp.2003.06.002
Reference
PMID:14586404
  Authors
DeArmond D, Brattain MG, Jessup JM, Kreisberg J, Malik S, Zhao S, Freeman JW.
  Title
Autocrine-mediated ErbB-2 kinase activation of STAT3 is required for growth factor independence of pancreatic cancer cell lines.
  Journal
Oncogene 22:7781-95 (2003)
DOI:10.1038/sj.onc.1206966
Reference
PMID:12545153
  Authors
Wei D, Le X, Zheng L, Wang L, Frey JA, Gao AC, Peng Z, Huang S, Xiong HQ, Abbruzzese JL, Xie K.
  Title
Stat3 activation regulates the expression of vascular endothelial growth factor and human pancreatic cancer angiogenesis and metastasis.
  Journal
Oncogene 22:319-29 (2003)
DOI:10.1038/sj.onc.1206122
Reference
PMID:14580692
  Authors
Toyonaga T, Nakano K, Nagano M, Zhao G, Yamaguchi K, Kuroki S, Eguchi T, Chijiiwa K, Tsuneyoshi M, Tanaka M.
  Title
Blockade of constitutively activated Janus kinase/signal transducer and activator of transcription-3 pathway inhibits growth of human pancreatic cancer.
  Journal
Cancer Lett 201:107-16 (2003)
DOI:10.1016/S0304-3835(03)00482-8
Reference
PMID:12079267
  Authors
Schmid RM.
  Title
Genetic basis of pancreatic cancer.
  Journal
Best Pract Res Clin Gastroenterol 16:421-33 (2002)
DOI:10.1053/bega.2002.0316
Reference
PMID:15774796
  Authors
Elliott RL, Blobe GC.
  Title
Role of transforming growth factor Beta in human cancer.
  Journal
J Clin Oncol 23:2078-93 (2005)
DOI:10.1200/JCO.2005.02.047
Reference
PMID:15823750
  Authors
Rudkin TM, Foulkes WD.
  Title
BRCA2: breaks, mistakes and failed separations.
  Journal
Trends Mol Med 11:145-8 (2005)
DOI:10.1016/j.molmed.2005.02.003
Reference
PMID:11707511
  Authors
Venkitaraman AR.
  Title
Functions of BRCA1 and BRCA2 in the biological response to DNA damage.
  Journal
J Cell Sci 114:3591-8 (2001)
Reference
PMID:15639402
  Authors
Soni D, King JA, Kaye AH, Hovens CM.
  Title
Genetics of glioblastoma multiforme: mitogenic signaling and cell cycle pathways converge.
  Journal
J Clin Neurosci 12:1-5 (2005)
DOI:10.1016/j.jocn.2004.04.001
Reference
PMID:12154354
  Authors
Zhu Y, Parada LF.
  Title
The molecular and genetic basis of neurological tumours.
  Journal
Nat Rev Cancer 2:616-26 (2002)
DOI:10.1038/nrc866
Reference
PMID:11253051
  Authors
Holland EC.
  Title
Gliomagenesis: genetic alterations and mouse models.
  Journal
Nat Rev Genet 2:120-9 (2001)
DOI:10.1038/35052535
Reference
PMID:16700615
  Authors
Bansal K, Liang ML, Rutka JT.
  Title
Molecular biology of human gliomas.
  Journal
Technol Cancer Res Treat 5:185-94 (2006)
DOI:10.1177/153303460600500302
Reference
  Authors
Tabuchi K (ed).
  Title
[Gliomas: Research and therapy] (In Japanese)
  Journal
Springer-Verlag Tokyo (2006)
Reference
PMID:12762887
  Authors
Kapoor GS, O'Rourke DM.
  Title
Mitogenic signaling cascades in glial tumors.
  Journal
Neurosurgery 52:1425-34; discussion 1434-5 (2003)
DOI:10.1227/01.NEU.0000065135.28143.39
Reference
PMID:16095998
  Authors
Hulleman E, Helin K.
  Title
Molecular mechanisms in gliomagenesis.
  Journal
Adv Cancer Res 94:1-27 (2005)
DOI:10.1016/S0065-230X(05)94001-3
Reference
PMID:11057895
  Authors
Schlessinger J.
  Title
Cell signaling by receptor tyrosine kinases.
  Journal
Cell 103:211-25 (2000)
DOI:10.1016/S0092-8674(00)00114-8
Reference
PMID:9643506
  Authors
Ng HK, Lam PY.
  Title
The molecular genetics of central nervous system tumors.
  Journal
Pathology 30:196-202 (1998)
DOI:10.1080/00313029800169236
Reference
PMID:12084351
  Authors
Knobbe CB, Merlo A, Reifenberger G.
  Title
Pten signaling in gliomas.
  Journal
Neuro-oncol 4:196-211 (2002)
DOI:10.1093/neuonc/4.3.196
Reference
PMID:16557281
  Authors
Kondo T, Ezzat S, Asa SL.
  Title
Pathogenetic mechanisms in thyroid follicular-cell neoplasia.
  Journal
Nat Rev Cancer 6:292-306 (2006)
DOI:10.1038/nrc1836
Reference
PMID:16551846
  Authors
Chiloeches A, Marais R.
  Title
Is BRAF the Achilles' Heel of thyroid cancer?
  Journal
Clin Cancer Res 12:1661-4 (2006)
DOI:10.1158/1078-0432.CCR-06-0051
Reference
PMID:16946003
  Authors
Reddi HV, McIver B, Grebe SK, Eberhardt NL
  Title
The paired box-8/peroxisome proliferator-activated receptor-gamma oncogene in thyroid tumorigenesis.
  Journal
Endocrinology 148:932-5 (2007)
DOI:10.1210/en.2006-0926
Reference
PMID:17062879
  Authors
Santoro M, Melillo RM, Fusco A.
  Title
RET/PTC activation in papillary thyroid carcinoma: European Journal of Endocrinology Prize Lecture.
  Journal
Eur J Endocrinol 155:645-653 (2006)
DOI:10.1530/eje.1.02289
Reference
PMID:16242838
  Authors
Pierotti MA, Greco A.
  Title
Oncogenic rearrangements of the NTRK1/NGF receptor.
  Journal
Cancer Lett 232:90-8 (2006)
DOI:10.1016/j.canlet.2005.07.043
Reference
PMID:16189702
  Authors
Sobrinho-Simoes M, Preto A, Rocha AS, Castro P, Maximo V, Fonseca E, Soares P.
  Title
Molecular pathology of well-differentiated thyroid carcinomas.
  Journal
Virchows Arch 447:787-93 (2005)
DOI:10.1007/s00428-005-0065-5
Reference
PMID:11165748
  Authors
Gimm O.
  Title
Thyroid cancer.
  Journal
Cancer Lett 163:143-56 (2001)
DOI:10.1016/S0304-3835(00)00697-2
Reference
PMID:12094241
  Authors
Williams D.
  Title
Cancer after nuclear fallout: lessons from the Chernobyl accident.
  Journal
Nat Rev Cancer 2:543-9 (2002)
DOI:10.1038/nrc845
Reference
PMID:16236521
  Authors
Steffen B, Muller-Tidow C, Schwable J, Berdel WE, Serve H.
  Title
The molecular pathogenesis of acute myeloid leukemia.
  Journal
Crit Rev Oncol Hematol 56:195-221 (2005)
DOI:10.1016/j.critrevonc.2004.10.012
Reference
PMID:12563308
  Authors
Tenen DG.
  Title
Disruption of differentiation in human cancer: AML shows the way.
  Journal
Nat Rev Cancer 3:89-101 (2003)
DOI:10.1038/nrc989
Reference
PMID:16146838
  Authors
Choudhary C, Muller-Tidow C, Berdel WE, Serve H.
  Title
Signal transduction of oncogenic Flt3.
  Journal
Int J Hematol 82:93-9 (2005)
DOI:10.1532/IJH97.05090
Reference
PMID:12951584
  Authors
Stirewalt DL, Radich JP.
  Title
The role of FLT3 in haematopoietic malignancies.
  Journal
Nat Rev Cancer 3:650-65 (2003)
DOI:10.1038/nrc1169
Reference
PMID:16642045
  Authors
Martelli AM, Nyakern M, Tabellini G, Bortul R, Tazzari PL, Evangelisti C, Cocco L.
  Title
Phosphoinositide 3-kinase/Akt signaling pathway and its therapeutical implications for human acute myeloid leukemia.
  Journal
Leukemia 20:911-28 (2006)
DOI:10.1038/sj.leu.2404245
Reference
PMID:15625120
  Authors
Lennartsson J, Jelacic T, Linnekin D, Shivakrupa R.
  Title
Normal and oncogenic forms of the receptor tyrosine kinase kit.
  Journal
Stem Cells 23:16-43 (2005)
DOI:10.1634/stemcells.2004-0117
Reference
PMID:11721960
  Authors
Lorsbach RB, Downing JR.
  Title
The role of the AML1 transcription factor in leukemogenesis.
  Journal
Int J Hematol 74:258-65 (2001)
DOI:10.1007/BF02982058
Reference
PMID:12468433
  Authors
Mizuki M, Schwable J, Steur C, Choudhary C, Agrawal S, Sargin B, Steffen B, Matsumura I, Kanakura Y, Bohmer FD, Muller-Tidow C, Berdel WE, Serve H.
  Title
Suppression of myeloid transcription factors and induction of STAT response genes by AML-specific Flt3 mutations.
  Journal
Blood 101:3164-73 (2003)
DOI:10.1182/blood-2002-06-1677
Reference
PMID:17554387
  Authors
Mikesch JH, Steffen B, Berdel WE, Serve H, Muller-Tidow C.
  Title
The emerging role of Wnt signaling in the pathogenesis of acute myeloid leukemia.
  Journal
Leukemia 21:1638-47 (2007)
DOI:10.1038/sj.leu.2404732
Reference
PMID:16352814
  Authors
Mueller BU, Pabst T, Fos J, Petkovic V, Fey MF, Asou N, Buergi U, Tenen DG.
  Title
ATRA resolves the differentiation block in t(15;17) acute myeloid leukemia by restoring PU.1 expression.
  Journal
Blood 107:3330-8 (2006)
DOI:10.1182/blood-2005-07-3068
Reference
PMID:15719031
  Authors
Ren R.
  Title
Mechanisms of BCR-ABL in the pathogenesis of chronic myelogenous leukaemia.
  Journal
Nat Rev Cancer 5:172-83 (2005)
DOI:10.1038/nrc1567
Reference
PMID:11071626
  Authors
Deininger MW, Goldman JM, Melo JV.
  Title
The molecular biology of chronic myeloid leukemia.
  Journal
Blood 96:3343-56 (2000)
Reference
PMID:14982876
  Authors
Calabretta B, Perrotti D.
  Title
The biology of CML blast crisis.
  Journal
Blood 103:4010-22 (2004)
DOI:10.1182/blood-2003-12-4111
Reference
PMID:10403855
  Authors
Faderl S, Talpaz M, Estrov Z, O'Brien S, Kurzrock R, Kantarjian HM.
  Title
The biology of chronic myeloid leukemia.
  Journal
N Engl J Med 341:164-72 (1999)
DOI:10.1056/NEJM199907153410306
Reference
PMID:15156182
  Authors
Mitani K.
  Title
Molecular mechanisms of leukemogenesis by AML1/EVI-1.
  Journal
Oncogene 23:4263-9 (2004)
DOI:10.1038/sj.onc.1207777
Reference
PMID:16484590
  Authors
Dong M, Blobe GC.
  Title
Role of transforming growth factor-beta in hematologic malignancies.
  Journal
Blood 107:4589-96 (2006)
DOI:10.1182/blood-2005-10-4169
Reference
PMID:9834202
  Authors
Kurokawa M, Mitani K, Imai Y, Ogawa S, Yazaki Y, Hirai H.
  Title
The t(3;21) fusion product, AML1/Evi-1, interacts with Smad3 and blocks transforming growth factor-beta-mediated growth inhibition of myeloid cells.
  Journal
Blood 92:4003-12 (1998)
Reference
PMID:12801837
  Authors
Brusa G, Benvenuti M, Mazzacurati L, Mancini M, Pattacini L, Martinelli G, Barbieri E, Greenberger JS, Baccarani M, Santucci MA.
  Title
p53 loss of function enhances genomic instability and accelerates clonal evolution of murine myeloid progenitors expressing the p(210)BCR-ABL tyrosine kinase.
  Journal
Haematologica 88:622-30 (2003)
Reference
PMID:11160144
  Authors
Baldwin AS.
  Title
Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kappaB.
  Journal
J Clin Invest 107:241-6 (2001)
DOI:10.1172/JCI11991
Reference
PMID:12244301
  Authors
Shin I, Yakes FM, Rojo F, Shin NY, Bakin AV, Baselga J, Arteaga CL.
  Title
PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localization.
  Journal
Nat Med 8:1145-52 (2002)
DOI:10.1038/nm759
Reference
PMID:15948971
  Authors
Tilli CM, Van Steensel MA, Krekels GA, Neumann HA, Ramaekers FC.
  Title
Molecular aetiology and pathogenesis of basal cell carcinoma.
  Journal
Br J Dermatol 152:1108-24 (2005)
DOI:10.1111/j.1365-2133.2005.06587.x
Reference
PMID:12588368
  Authors
Saldanha G, Fletcher A, Slater DN.
  Title
Basal cell carcinoma: a dermatopathological and molecular biological update.
  Journal
Br J Dermatol 148:195-202 (2003)
DOI:10.1046/j.1365-2133.2003.05151.x
Reference
PMID:15978322
  Authors
Daya-Grosjean L, Couve-Privat S.
  Title
Sonic hedgehog signaling in basal cell carcinomas.
  Journal
Cancer Lett 225:181-92 (2005)
DOI:10.1016/j.canlet.2004.10.003
Reference
PMID:15468170
  Authors
Tsai KY, Tsao H.
  Title
The genetics of skin cancer.
  Journal
Am J Med Genet C Semin Med Genet 131C:82-92 (2004)
DOI:10.1002/ajmg.c.30037
Reference
PMID:16881963
  Authors
Athar M, Tang X, Lee JL, Kopelovich L, Kim AL.
  Title
Hedgehog signalling in skin development and cancer.
  Journal
Exp Dermatol 15:667-77 (2006)
DOI:10.1111/j.1600-0625.2006.00473.x
Reference
PMID:16306523
  Authors
Rubin AI, Chen EH, Ratner D.
  Title
Basal-cell carcinoma.
  Journal
N Engl J Med 353:2262-9 (2005)
DOI:10.1056/NEJMra044151
Reference
PMID:11276000
  Authors
Saldanha G.
  Title
The Hedgehog signalling pathway and cancer.
  Journal
J Pathol 193:427-32 (2001)
DOI:10.1002/1096-9896(2000)9999:9999<::AID-PATH815>3.0.CO;2-N
Reference
PMID:15270885
  Authors
Saldanha G, Ghura V, Potter L, Fletcher A.
  Title
Nuclear beta-catenin in basal cell carcinoma correlates with increased proliferation.
  Journal
Br J Dermatol 151:157-64 (2004)
DOI:10.1111/j.1365-2133.2004.06048.x
Reference
PMID:14737121
  Authors
Pasca di Magliano M, Hebrok M.
  Title
Hedgehog signalling in cancer formation and maintenance.
  Journal
Nat Rev Cancer 3:903-11 (2003)
DOI:10.1038/nrc1229
Reference
PMID:15656799
  Authors
Reifenberger J, Wolter M, Knobbe CB, Kohler B, Schonicke A, Scharwachter C, Kumar K, Blaschke B, Ruzicka T, Reifenberger G.
  Title
Somatic mutations in the PTCH, SMOH, SUFUH and TP53 genes in sporadic basal cell carcinomas.
  Journal
Br J Dermatol 152:43-51 (2005)
DOI:10.1111/j.1365-2133.2005.06353.x
Reference
PMID:14556242
  Authors
Cohen MM Jr.
  Title
The hedgehog signaling network.
  Journal
Am J Med Genet A 123:5-28 (2003)
DOI:10.1002/ajmg.a.20495
Reference
PMID:11736900
  Authors
Yamazaki F, Aragane Y, Kawada A, Tezuka T.
  Title
Immunohistochemical detection for nuclear beta-catenin in sporadic basal cell carcinoma.
  Journal
Br J Dermatol 145:771-7 (2001)
DOI:10.1046/j.1365-2133.2001.04468.x
Reference
PMID:16054233
  Authors
Erb P, Ji J, Wernli M, Kump E, Glaser A, Buchner SA.
  Title
Role of apoptosis in basal cell and squamous cell carcinoma formation.
  Journal
Immunol Lett 100:68-72 (2005)
DOI:10.1016/j.imlet.2005.06.008
Reference
PMID:11130178
  Authors
Toftgard R.
  Title
Hedgehog signalling in cancer.
  Journal
Cell Mol Life Sci 57:1720-31 (2000)
DOI:10.1007/PL00000654
Reference
PMID:16822996
  Authors
Miller AJ, Mihm MC Jr.
  Title
Melanoma.
  Journal
N Engl J Med 355:51-65 (2006)
DOI:10.1056/NEJMra052166
Reference
PMID:12894244
  Authors
Chin L.
  Title
The genetics of malignant melanoma: lessons from mouse and man.
  Journal
Nat Rev Cancer 3:559-70 (2003)
DOI:10.1038/nrc1145
Reference
PMID:16750612
  Authors
Takata M, Saida T.
  Title
Genetic alterations in melanocytic tumors.
  Journal
J Dermatol Sci 43:1-10 (2006)
DOI:10.1016/j.jdermsci.2006.05.002
Reference
PMID:15841168
  Authors
Chudnovsky Y, Khavari PA, Adams AE.
  Title
Melanoma genetics and the development of rational therapeutics.
  Journal
J Clin Invest 115:813-24 (2005)
DOI:10.1172/JCI24808
Reference
PMID:16001050
  Authors
Merlino G.
  Title
Cancer biology: the weakest link?
  Journal
Nature 436:33-5 (2005)
DOI:10.1038/436033a
Reference
PMID:16001072
  Authors
Garraway LA, Widlund HR, Rubin MA, Getz G, Berger AJ, Ramaswamy S, Beroukhim R, Milner DA, Granter SR, Du J, Lee C, Wagner SN, Li C, Golub TR, Rimm DL, Meyerson ML, Fisher DE, Sellers WR.
  Title
Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma.
  Journal
Nature 436:117-22 (2005)
DOI:10.1038/nature03664
Reference
PMID:16899407
  Authors
Levy C, Khaled M, Fisher DE.
  Title
MITF: master regulator of melanocyte development and melanoma oncogene.
  Journal
Trends Mol Med 12:406-14 (2006)
DOI:10.1016/j.molmed.2006.07.008
Reference
PMID:15009714
  Authors
Tsao H, Goel V, Wu H, Yang G, Haluska FG.
  Title
Genetic interaction between NRAS and BRAF mutations and PTEN/MMAC1 inactivation in melanoma.
  Journal
J Invest Dermatol 122:337-41 (2004)
DOI:10.1046/j.0022-202X.2004.22243.x
Reference
PMID:11224709
  Authors
Gruss C, Herlyn M.
  Title
Role of cadherins and matrixins in melanoma.
  Journal
Curr Opin Oncol 13:117-23 (2001)
DOI:10.1097/00001622-200103000-00006
Reference
PMID:15721476
  Authors
Thompson JF, Scolyer RA, Kefford RF.
  Title
Cutaneous melanoma.
  Journal
Lancet 365:687-701 (2005)
DOI:10.1016/S0140-6736(05)17951-3
Reference
PMID:14695152
  Authors
Omholt K, Platz A, Kanter L, Ringborg U, Hansson J.
  Title
NRAS and BRAF mutations arise early during melanoma pathogenesis and are preserved throughout tumor progression.
  Journal
Clin Cancer Res 9:6483-8 (2003)
Reference
PMID:15557758
  Authors
Hussein MR.
  Title
The TP53 tumor suppressor gene and melanoma tumorigenesis: is there a relationship?
  Journal
Tumour Biol 25:200-7 (2004)
DOI:10.1159/000081103
Reference
PMID:10843728
  Authors
Lazar-Molnar E, Hegyesi H, Toth S, Falus A.
  Title
Autocrine and paracrine regulation by cytokines and growth factors in melanoma.
  Journal
Cytokine 12:547-54 (2000)
DOI:10.1006/cyto.1999.0614
Reference
PMID:16339096
  Authors
Cohen HT, McGovern FJ.
  Title
Renal-cell carcinoma.
  Journal
N Engl J Med 353:2477-90 (2005)
DOI:10.1056/NEJMra043172
Reference
PMID:15122209
  Authors
Pavlovich CP, Schmidt LS.
  Title
Searching for the hereditary causes of renal-cell carcinoma.
  Journal
Nat Rev Cancer 4:381-93 (2004)
DOI:10.1038/nrc1364
Reference
PMID:14634372
  Authors
Linehan WM, Walther MM, Zbar B.
  Title
The genetic basis of cancer of the kidney.
  Journal
J Urol 170:2163-72 (2003)
DOI:10.1097/01.ju.0000096060.92397.ed
Reference
PMID:14685170
  Authors
Birchmeier C, Birchmeier W, Gherardi E, Vande Woude GF.
  Title
Met, metastasis, motility and more.
  Journal
Nat Rev Mol Cell Biol 4:915-25 (2003)
DOI:10.1038/nrm1261
Reference
PMID:15611513
  Authors
Kim WY, Kaelin WG.
  Title
Role of VHL gene mutation in human cancer.
  Journal
J Clin Oncol 22:4991-5004 (2004)
DOI:10.1200/JCO.2004.05.061
Reference
PMID:17211469
  Authors
Sudarshan S, Linehan WM, Neckers L.
  Title
HIF and fumarate hydratase in renal cancer.
  Journal
Br J Cancer 96:403-7 (2007)
DOI:10.1038/sj.bjc.6603547
Reference
PMID:17287871
  Authors
Sudarshan S, Pinto PA, Neckers L, Linehan WM.
  Title
Mechanisms of disease: hereditary leiomyomatosis and renal cell cancer--a distinct form of hereditary kidney cancer.
  Journal
Nat Clin Pract Urol 4:104-10 (2007)
DOI:10.1038/ncpuro0711
Reference
PMID:12351585
  Authors
Bodmer D, van den Hurk W, van Groningen JJ, Eleveld MJ, Martens GJ, Weterman MA, van Kessel AG.
  Title
Understanding familial and non-familial renal cell cancer.
  Journal
Hum Mol Genet 11:2489-98 (2002)
DOI:10.1093/hmg/11.20.2489
Reference
PMID:17158541
  Authors
Mitra AP, Datar RH, Cote RJ.
  Title
Molecular pathways in invasive bladder cancer: new insights into mechanisms, progression, and target identification.
  Journal
J Clin Oncol 24:5552-64 (2006)
DOI:10.1200/JCO.2006.08.2073
Reference
PMID:16474624
  Authors
Wolff EM, Liang G, Jones PA.
  Title
Mechanisms of Disease: genetic and epigenetic alterations that drive bladder cancer.
  Journal
Nat Clin Pract Urol 2:502-10 (2005)
DOI:10.1038/ncpuro0318
Reference
PMID:16110317
  Authors
Wu XR.
  Title
Urothelial tumorigenesis: a tale of divergent pathways.
  Journal
Nat Rev Cancer 5:713-25 (2005)
DOI:10.1038/nrc1697
Reference
PMID:11103787
  Authors
Brown NS, Jones A, Fujiyama C, Harris AL, Bicknell R.
  Title
Thymidine phosphorylase induces carcinoma cell oxidative stress and promotes secretion of angiogenic factors.
  Journal
Cancer Res 60:6298-302 (2000)
Reference
PMID:12850530
  Authors
Bellmunt J, Hussain M, Dinney CP.
  Title
Novel approaches with targeted therapies in bladder cancer. Therapy of bladder cancer by blockade of the epidermal growth factor receptor family.
  Journal
Crit Rev Oncol Hematol 46 Suppl:S85-104 (2003)
DOI:10.1016/S1040-8428(03)00067-2
Reference
PMID:17149381
  Authors
Sugano K, Kakizoe T.
  Title
Genetic alterations in bladder cancer and their clinical applications in molecular tumor staging.
  Journal
Nat Clin Pract Urol 3:642-52 (2006)
DOI:10.1038/ncpuro0649
Reference
PMID:15746962
  Authors
Dunn KL, Espino PS, Drobic B, He S, Davie JR.
  Title
The Ras-MAPK signal transduction pathway, cancer and chromatin remodeling.
  Journal
Biochem Cell Biol 83:1-14 (2005)
DOI:10.1139/o04-121
Reference
PMID:15551095
  Authors
Williams SG, Stein JP.
  Title
Molecular pathways in bladder cancer.
  Journal
Urol Res 32:373-85 (2004)
DOI:10.1007/s00240-003-0345-y
Reference
PMID:12878745
  Authors
Nelson WG, De Marzo AM, Isaacs WB.
  Title
Prostate cancer.
  Journal
N Engl J Med 349:366-81 (2003)
DOI:10.1056/NEJMra021562
Reference
PMID:15724144
  Authors
Li L, Ittmann MM, Ayala G, Tsai MJ, Amato RJ, Wheeler TM, Miles BJ, Kadmon D, Thompson TC.
  Title
The emerging role of the PI3-K-Akt pathway in prostate cancer progression.
  Journal
Prostate Cancer Prostatic Dis 8:108-18 (2005)
DOI:10.1038/sj.pcan.4500776
Reference
PMID:16551847
  Authors
Pienta KJ, Bradley D.
  Title
Mechanisms underlying the development of androgen-independent prostate cancer.
  Journal
Clin Cancer Res 12:1665-71 (2006)
DOI:10.1158/1078-0432.CCR-06-0067
Reference
PMID:11900250
  Authors
Feldman BJ, Feldman D.
  Title
The development of androgen-independent prostate cancer.
  Journal
Nat Rev Cancer 1:34-45 (2001)
DOI:10.1038/35094009
Reference
PMID:15082523
  Authors
Heinlein CA, Chang C.
  Title
Androgen receptor in prostate cancer.
  Journal
Endocr Rev 25:276-308 (2004)
DOI:10.1210/er.2002-0032
Reference
PMID:9422516
  Authors
Koivisto P, Kolmer M, Visakorpi T, Kallioniemi OP.
  Title
Androgen receptor gene and hormonal therapy failure of prostate cancer.
  Journal
Am J Pathol 152:1-9 (1998)
Reference
PMID:10835690
  Authors
Zhao XY, Malloy PJ, Krishnan AV, Swami S, Navone NM, Peehl DM, Feldman D.
  Title
Glucocorticoids can promote androgen-independent growth of prostate cancer cells through a mutated androgen receptor.
  Journal
Nat Med 6:703-6 (2000)
DOI:10.1038/76287
Reference
PMID:10453277
  Authors
Macri E, Loda M.
  Title
Role of p27 in prostate carcinogenesis.
  Journal
Cancer Metastasis Rev 17:337-44 (1998)
DOI:10.1023/A:1006133620914
Reference
PMID:11750244
  Authors
Steers WD.
  Title
5alpha-reductase activity in the prostate.
  Journal
Urology 58:17-24; discussion 24 (2001)
DOI:10.1016/S0090-4295(01)01299-7
Reference
PMID:8069858
  Authors
Lin D, Meyer DJ, Ketterer B, Lang NP, Kadlubar FF.
  Title
Effects of human and rat glutathione S-transferases on the covalent DNA binding of the N-acetoxy derivatives of heterocyclic amine carcinogens in vitro: a possible mechanism of organ specificity in their carcinogenesis.
  Journal
Cancer Res 54:4920-6 (1994)
Reference
PMID:11527574
  Authors
Grimes CA, Jope RS.
  Title
The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling.
  Journal
Prog Neurobiol 65:391-426 (2001)
DOI:10.1016/S0301-0082(01)00011-9
Reference
PMID:15947972
  Authors
Ryan AJ, Susil B, Jobling TW, Oehler MK.
  Title
Endometrial cancer.
  Journal
Cell Tissue Res 322:53-61 (2005)
DOI:10.1007/s00441-005-1109-5
Reference
PMID:14747944
  Authors
Lax SF.
  Title
Molecular genetic pathways in various types of endometrial carcinoma: from a phenotypical to a molecular-based classification.
  Journal
Virchows Arch 444:213-23 (2004)
DOI:10.1007/s00428-003-0947-3
Reference
PMID:16508724
  Authors
Shiozawa T, Konishi I.
  Title
Early endometrial carcinoma: clinicopathology, hormonal aspects, molecular genetics, diagnosis, and treatment.
  Journal
Int J Clin Oncol 11:13-21 (2006)
DOI:10.1007/s10147-005-0546-1
Reference
PMID:17028294
  Authors
Hecht JL, Mutter GL.
  Title
Molecular and pathologic aspects of endometrial carcinogenesis.
  Journal
J Clin Oncol 24:4783-91 (2006)
DOI:10.1200/JCO.2006.06.7173
Reference
PMID:11431710
  Authors
Matias-Guiu X, Catasus L, Bussaglia E, Lagarda H, Garcia A, Pons C, Munoz J, Arguelles R, Machin P, Prat J.
  Title
Molecular pathology of endometrial hyperplasia and carcinoma.
  Journal
Hum Pathol 32:569-77 (2001)
DOI:10.1053/hupa.2001.25929
Reference
PMID:15284264
  Authors
Slomovitz BM, Broaddus RR, Burke TW, Sneige N, Soliman PT, Wu W, Sun CC, Munsell MF, Gershenson DM, Lu KH.
  Title
Her-2/neu overexpression and amplification in uterine papillary serous carcinoma.
  Journal
J Clin Oncol 22:3126-32 (2004)
DOI:10.1200/JCO.2004.11.154
Reference
PMID:7585656
  Authors
Saffari B, Jones LA, el-Naggar A, Felix JC, George J, Press MF.
  Title
Amplification and overexpression of HER-2/neu (c-erbB2) in endometrial cancers: correlation with overall survival.
  Journal
Cancer Res 55:5693-8 (1995)
Reference
PMID:16248975
  Authors
Kim D, Chung J.
  Title
Akt: versatile mediator of cell survival and beyond.
  Journal
J Biochem Mol Biol 35:106-15 (2002)
DOI:10.5483/bmbrep.2002.35.1.106
Reference
PMID:12711111
  Authors
Sanchez-Cespedes M.
  Title
Dissecting the genetic alterations involved in lung carcinogenesis.
  Journal
Lung Cancer 40:111-21 (2003)
DOI:10.1016/S0169-5002(03)00033-3
Reference
PMID:11720739
  Authors
Kaye FJ.
  Title
Molecular biology of lung cancer.
  Journal
Lung Cancer 34 Suppl 2:S35-41 (2001)
DOI:10.1016/S0169-5002(01)00342-7
Reference
PMID:12616528
  Authors
Shivapurkar N, Reddy J, Chaudhary PM, Gazdar AF.
  Title
Apoptosis and lung cancer: a review.
  Journal
J Cell Biochem 88:885-98 (2003)
DOI:10.1002/jcb.10440
Reference
PMID:11807782
  Authors
Sartorius UA, Krammer PH.
  Title
Upregulation of Bcl-2 is involved in the mediation of chemotherapy resistance in human small cell lung cancer cell lines.
  Journal
Int J Cancer 97:584-92 (2002)
DOI:10.1002/ijc.10096
Reference
PMID:16064138
  Authors
Adhikary S, Eilers M.
  Title
Transcriptional regulation and transformation by Myc proteins.
  Journal
Nat Rev Mol Cell Biol 6:635-45 (2005)
DOI:10.1038/nrm1703
Reference
PMID:11463388
  Authors
Spruck C, Strohmaier H, Watson M, Smith AP, Ryan A, Krek TW, Reed SI.
  Title
A CDK-independent function of mammalian Cks1: targeting of SCF(Skp2) to the CDK inhibitor p27Kip1.
  Journal
Mol Cell 7:639-50 (2001)
DOI:10.1016/S1097-2765(01)00210-6
Reference
PMID:15109562
  Authors
Buttery RC, Rintoul RC, Sethi T.
  Title
Small cell lung cancer: the importance of the extracellular matrix.
  Journal
Int J Biochem Cell Biol 36:1154-60 (2004)
DOI:10.1016/S1357-2725(03)00261-9
Reference
PMID:11559746
  Authors
Yamada KM, Araki M.
  Title
Tumor suppressor PTEN: modulator of cell signaling, growth, migration and apoptosis.
  Journal
J Cell Sci 114:2375-82 (2001)
Reference
PMID:11905738
  Authors
Rintoul RC, Sethi T.
  Title
The role of extracellular matrix in small-cell lung cancer.
  Journal
Lancet Oncol 2:437-42 (2001)
DOI:10.1016/S1470-2045(00)00421-6
Reference
PMID:12243753
  Authors
Ekedahl J, Joseph B, Grigoriev MY, Muller M, Magnusson C, Lewensohn R, Zhivotovsky B.
  Title
Expression of inhibitor of apoptosis proteins in small- and non-small-cell lung carcinoma cells.
  Journal
Exp Cell Res 279:277-90 (2002)
DOI:10.1006/excr.2002.5608
Reference
PMID:12379883
  Authors
Osada H, Takahashi T.
  Title
Genetic alterations of multiple tumor suppressors and oncogenes in the carcinogenesis and progression of lung cancer.
  Journal
Oncogene 21:7421-34 (2002)
DOI:10.1038/sj.onc.1205802
Reference
PMID:12741677
  Authors
Yokota J, Nishioka M, Tani M, Kohno T.
  Title
Genetic alterations responsible for metastatic phenotypes of lung cancer cells.
  Journal
Clin Exp Metastasis 20:189-93 (2003)
DOI:10.1023/a:1022978932215
Reference
PMID:16870043
  Authors
Aviel-Ronen S, Blackhall FH, Shepherd FA, Tsao MS.
  Title
K-ras mutations in non-small-cell lung carcinoma: a review.
  Journal
Clin Lung Cancer 8:30-8 (2006)
DOI:10.3816/CLC.2006.n.030
Reference
PMID:15948711
  Authors
Pfeifer GP, Dammann R.
  Title
Methylation of the tumor suppressor gene RASSF1A in human tumors.
  Journal
Biochemistry (Mosc) 70:576-83 (2005)
DOI:10.1007/s10541-005-0151-y
Reference
PMID:11902573
  Authors
Altucci L, Gronemeyer H.
  Title
The promise of retinoids to fight against cancer.
  Journal
Nat Rev Cancer 1:181-93 (2001)
DOI:10.1038/35106036
Reference
PMID:10944551
  Authors
Virmani AK, Rathi A, Zochbauer-Muller S, Sacchi N, Fukuyama Y, Bryant D, Maitra A, Heda S, Fong KM, Thunnissen F, Minna JD, Gazdar AF.
  Title
Promoter methylation and silencing of the retinoic acid receptor-beta gene in lung carcinomas.
  Journal
J Natl Cancer Inst 92:1303-7 (2000)
DOI:10.1093/jnci/92.16.1303
Reference
PMID:12867060
  Authors
Hirsch FR, Scagliotti GV, Langer CJ, Varella-Garcia M, Franklin WA.
  Title
Epidermal growth factor family of receptors in preneoplasia and lung cancer: perspectives for targeted therapies.
  Journal
Lung Cancer 41 Suppl 1:S29-42 (2003)
DOI:10.1016/S0169-5002(03)00137-5
Reference
PMID:16112428
  Authors
Panani AD, Roussos C.
  Title
Cytogenetic and molecular aspects of lung cancer.
  Journal
Cancer Lett 239:1-9 (2006)
DOI:10.1016/j.canlet.2005.06.030
Reference
PMID:12407699
  Authors
Mitsuuchi Y, Testa JR.
  Title
Cytogenetics and molecular genetics of lung cancer.
  Journal
Am J Med Genet 115:183-8 (2002)
DOI:10.1002/ajmg.10692
Reference
PMID:15942304
  Authors
Breuer RH, Postmus PE, Smit EF.
  Title
Molecular pathology of non-small-cell lung cancer.
  Journal
Respiration 72:313-30 (2005)
DOI:10.1159/000085376
Reference
PMID:11895903
  Authors
Piyathilake CJ, Frost AR, Manne U, Weiss H, Bell WC, Heimburger DC, Grizzle WE.
  Title
Differential expression of growth factors in squamous cell carcinoma and precancerous lesions of the lung.
  Journal
Clin Cancer Res 8:734-44 (2002)
Reference
PMID:16189154
  Authors
Awaya H, Takeshima Y, Furonaka O, Kohno N, Inai K.
  Title
Gene amplification and protein expression of EGFR and HER2 by chromogenic in situ hybridisation and immunohistochemistry in atypical adenomatous hyperplasia and adenocarcinoma of the lung.
  Journal
J Clin Pathol 58:1076-80 (2005)
DOI:10.1136/jcp.2004.025585
Reference
PMID:21193867
  Authors
Lappano R, Maggiolini M
  Title
G protein-coupled receptors: novel targets for drug discovery in cancer.
  Journal
Nat Rev Drug Discov 10:47-60 (2011)
DOI:10.1038/nrd3320
Reference
PMID:24508914
  Authors
O'Hayre M, Degese MS, Gutkind JS
  Title
Novel insights into G protein and G protein-coupled receptor signaling in cancer.
  Journal
Curr Opin Cell Biol 27:126-35 (2014)
DOI:10.1016/j.ceb.2014.01.005
Reference
PMID:17251915
  Authors
Dorsam RT, Gutkind JS
  Title
G-protein-coupled receptors and cancer.
  Journal
Nat Rev Cancer 7:79-94 (2007)
DOI:10.1038/nrc2069
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