KEGG Orthology (KO)

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 09100 Metabolism
 
 09120 Genetic Information Processing
 
 09130 Environmental Information Processing
 
   09131 Membrane transport
 
   09132 Signal transduction
     02020 Two-component system [PATH:ko02020]
     04010 MAPK signaling pathway [PATH:ko04010]
     04013 MAPK signaling pathway - fly [PATH:ko04013]
     04016 MAPK signaling pathway - plant [PATH:ko04016]
     04011 MAPK signaling pathway - yeast [PATH:ko04011]
     04012 ErbB signaling pathway [PATH:ko04012]
     04014 Ras signaling pathway [PATH:ko04014]
     04015 Rap1 signaling pathway [PATH:ko04015]
     04310 Wnt signaling pathway [PATH:ko04310]
     04330 Notch signaling pathway [PATH:ko04330]
     04340 Hedgehog signaling pathway [PATH:ko04340]
       K06225  PTCH1; patched 1
       K11101  PTCH2; patched 2
       K06226  SMO; smoothened
       K08439  GPR161; G protein-coupled receptor 161
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K08957  CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]
       K08958  CSNK1G; casein kinase 1, gamma [EC:2.7.11.1]
       K08959  CSNK1D; casein kinase 1, delta [EC:2.7.11.1]
       K08960  CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]
       K03083  GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
       K16797  GLI1; zinc finger protein GLI1
       K16798  GLI2; zinc finger protein GLI2
       K06230  GLI3; zinc finger protein GLI3
       K06229  SUFU; suppressor of fused
       K18806  KIF7; kinesin family member 7
       K06231  HHIP; hedgehog interacting protein
       K04503  CCND1; G1/S-specific cyclin-D1
       K10151  CCND2; G1/S-specific cyclin-D2
       K02161  BCL2; apoptosis regulator Bcl-2
       K03347  CUL1, CDC53; cullin 1
       K03362  FBXW1_11, BTRC, beta-TRCP; F-box and WD-40 domain protein 1/11
       K24678  HHAT; protein-cysteine N-palmitoyltransferase HHAT [EC:2.3.1.-]
       K24679  HHATL; protein-cysteine N-palmitoyltransferase HHAT-like protein
       K11988  SHH; sonic hedgehog
       K11989  IHH; indian hedgehog
       K11990  DHH; desert hedgehog
       K24680  DISP1; protein dispatched 1
       K24706  SCUBE2; signal peptide, CUB and EGF-like domain-containing protein 2
       K20020  BOC; brother of CDO
       K20033  CDON, CDO; cell adhesion molecule-related/down-regulated by oncogenes
       K06232  GAS1; growth arrest-specific 1
       K06233  LRP2; low density lipoprotein-related protein 2
       K23663  MOSMO; modulator of smoothened protein
       K23664  MEGF8; multipile epidermal growth factor-like domains protein 8
       K10604  MGRN1; E3 ubiquitin-protein ligase MGRN1 [EC:2.3.2.27]
       K04678  SMURF; E3 ubiquitin ligase SMURF1/2 [EC:2.3.2.26]
       K00910  ADRBK, GRK; beta-adrenergic-receptor kinase [EC:2.7.11.15]
       K19605  EVC1; ellis van creveld syndrome protein 1
       K19608  EVC2; ellis van creveld syndrome protein 2
       K23852  EFCAB7; EF-hand calcium-binding domain-containing protein 7
       K24677  IQCE; IQ domain-contaning protein E
       K04439  ARRB; beta-arrestin
       K10394  KIF3A; kinesin family member 3A
       K03869  CUL3; cullin 3
       K10523  SPOP; speckle-type POZ protein
     04341 Hedgehog signaling pathway - fly [PATH:ko04341]
       K06225  PTCH1; patched 1
       K06226  SMO; smoothened
       K06227  COS2; costal 2
       K06228  FU; fused [EC:2.7.11.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K08957  CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]
       K08958  CSNK1G; casein kinase 1, gamma [EC:2.7.11.1]
       K08960  CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]
       K03083  GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
       K16799  CI; transcriptional activator cubitus interruptus
       K06229  SUFU; suppressor of fused
       K03362  FBXW1_11, BTRC, beta-TRCP; F-box and WD-40 domain protein 1/11
       K03347  CUL1, CDC53; cullin 1
       K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
       K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
       K10523  SPOP; speckle-type POZ protein
       K04662  BMP4; bone morphogenetic protein 4
       K09319  EN; homeobox protein engrailed
       K06224  HH; hedgehog
       K24678  HHAT; protein-cysteine N-palmitoyltransferase HHAT [EC:2.3.1.-]
       K24680  DISP1; protein dispatched 1
       K20244  IHOG; interference hedgohog
       K20245  BOI; brother of ihog
       K04678  SMURF; E3 ubiquitin ligase SMURF1/2 [EC:2.3.2.26]
       K08291  GRK4_5_6; G protein-coupled receptor kinase [EC:2.7.11.16]
       K03869  CUL3; cullin 3
     04350 TGF-beta signaling pathway [PATH:ko04350]
     04390 Hippo signaling pathway [PATH:ko04390]
     04391 Hippo signaling pathway - fly [PATH:ko04391]
     04392 Hippo signaling pathway - multiple species [PATH:ko04392]
     04370 VEGF signaling pathway [PATH:ko04370]
     04371 Apelin signaling pathway [PATH:ko04371]
     04630 JAK-STAT signaling pathway [PATH:ko04630]
     04064 NF-kappa B signaling pathway [PATH:ko04064]
     04668 TNF signaling pathway [PATH:ko04668]
     04066 HIF-1 signaling pathway [PATH:ko04066]
     04068 FoxO signaling pathway [PATH:ko04068]
     04020 Calcium signaling pathway [PATH:ko04020]
     04070 Phosphatidylinositol signaling system [PATH:ko04070]
     04072 Phospholipase D signaling pathway [PATH:ko04072]
     04071 Sphingolipid signaling pathway [PATH:ko04071]
     04024 cAMP signaling pathway [PATH:ko04024]
       K05264  VIP; vasoactive intestinal peptide
       K05256  CRH; corticotropin-releasing hormone
       K08522  CGA; glycoprotein hormones alpha chain
       K08521  LHB; lutropin subunit beta
       K25483  GPHA2; glycoprotein hormone alpha-2
       K25484  GPHB5; glycoprotein hormone beta-5
       K05251  TSHB; thyrotropin subunit beta
       K05228  POMC; proopiomelanocortin
       K05259  GCG; glucagon
       K05258  GIP; gastric inhibitory polypeptide
       K05250  FSHB; follitropin subunit beta
       K12334  NPPA; natriuretic peptide A
       K05262  ADCYAP; pituitary adenylate cyclase-activating polypeptide
       K04141  ADRB1; adrenergic receptor beta-1
       K04142  ADRB2; adrenergic receptor beta-2
       K04144  DRD1; dopamine receptor D1
       K05840  DRD5; dopamine receptor D5
       K04266  ADORA2A, ADOR; adenosine receptor A2a
       K04160  HTR4; 5-hydroxytryptamine receptor 4
       K04162  HTR6; 5-hydroxytryptamine receptor 6
       K04259  PTGER2; prostaglandin E receptor 2
       K04587  ADCYAP1R1, PACAPRI; pituitary adenylate cyclase-activating polypeptide type I receptor
       K04590  VIPR2; vasoactive intestinal peptide receptor 2
       K04578  CRHR1; corticotropin releasing hormone receptor 1
       K04579  CRHR2; corticotropin releasing hormone receptor 2
       K04248  LHCGR; lutropin-choriogonadotropic hormone receptor
       K04249  TSHR; thyrotropin receptor
       K04200  MC2R; melanocortin 2 receptor
       K04581  GLP1R; glucagon-like peptide 1 receptor
       K04580  GIPR; gastric inhibitory polypeptide receptor
       K08424  GPR119; glucose-dependent insulinotropic receptor
       K04247  FSHR; follicle stimulating hormone receptor
       K12323  ANPRA, NPR1; atrial natriuretic peptide receptor A [EC:4.6.1.2]
       K04632  GNAS; guanine nucleotide-binding protein G(s) subunit alpha
       K16366  EDN1; endothelin-1
       K16367  EDN2; endothelin-2
       K05227  EDN3; endothelin-3
       K05237  SST; somatostatin
       K05232  NPY; neuropeptide Y
       K05254  GHRL; ghrelin
       K05243  OXT; oxytocin-neurophysin 1
       K04153  HTR1; 5-hydroxytryptamine receptor 1
       K04129  CHRM1; muscarinic acetylcholine receptor M1
       K04130  CHRM2; muscarinic acetylcholine receptor M2
       K04145  DRD2; dopamine receptor D2
       K04615  GABBR; gamma-aminobutyric acid type B receptor
       K04265  ADORA1; adenosine receptor A1
       K04197  EDNRA; endothelin receptor type A
       K04204  NPY1R; neuropeptide Y receptor type 1
       K04217  SSTR1; somatostatin receptor 1
       K04218  SSTR2; somatostatin receptor 2
       K04221  SSTR5; somatostatin receptor 5
       K08401  HCAR1, GPR81; hydroxycarboxylic acid receptor 1
       K08402  HCAR2_3, GPR109; hydroxycarboxylic acid receptor 2/3
       K04328  FFAR2, GPR43; free fatty acid receptor 2
       K10042  SUCNR1, GPR91; succinate receptor 1
       K04260  PTGER3; prostaglandin E receptor 3
       K04229  OXTR; oxytocin receptor
       K04284  GHSR; growth hormone secretagogue receptor
       K04630  GNAI; guanine nucleotide-binding protein G(i) subunit alpha
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K11265  ADCY10; adenylate cyclase 10 [EC:4.6.1.1]
       K04948  CNGA1; cyclic nucleotide gated channel alpha 1
       K04949  CNGA2; cyclic nucleotide gated channel alpha 2
       K04950  CNGA3; cyclic nucleotide gated channel alpha 3
       K04951  CNGA4; cyclic nucleotide gated channel alpha 4
       K04952  CNGB1; cyclic nucleotide gated channel beta 1
       K04953  CNGB3; cyclic nucleotide gated channel beta 3
       K02183  CALM; calmodulin
       K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
       K05869  CAMK4; calcium/calmodulin-dependent protein kinase IV [EC:2.7.11.17]
       K21108  BVES, POPDC1; blood vessel epicardial substance
       K26206  POPDC2; popeye domain-containing protein 2
       K26207  POPDC3; popeye domain-containing protein 3
       K04913  KCNK2, K2P2.1; potassium channel subfamily K member 2
       K04955  HCN2; hyperpolarization activated cyclic nucleotide-gated potassium channel 2
       K04957  HCN4; hyperpolarization activated cyclic nucleotide-gated potassium channel 4
       K05673  ABCC4; ATP-binding cassette, subfamily C (CFTR/MRP), member 4
       K08014  RAPGEF3, EPAC1; Rap guanine nucleotide exchange factor 3
       K04351  RAPGEF4, EPAC2; Rap guanine nucleotide exchange factor 4
       K07829  RRAS; Ras-related protein R-Ras
       K07830  RRAS2, TC21; Ras-related protein R-Ras2
       K01115  PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
       K05860  PLCE; phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
       K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
       K04353  RAP1A; Ras-related protein Rap-1A
       K07836  RAP1B; Ras-related protein Rap-1B
       K05731  TIAM1; T-lymphoma invasion and metastasis-inducing protein 1
       K05730  VAV; guanine nucleotide exchange factor VAV
       K04392  RAC1; Ras-related C3 botulinum toxin substrate 1
       K07860  RAC2; Ras-related C3 botulinum toxin substrate 2
       K07861  RAC3; Ras-related C3 botulinum toxin substrate 3
       K04409  PAK1; p21-activated kinase 1 [EC:2.7.11.1]
       K12490  ARAP3; Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
       K04513  RHOA; Ras homolog gene family, member A
       K05702  AF6, MLLT4; afadin
       K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
       K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K04365  BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K15494  PPP1R1B, DARPP32; protein phosphatase 1 regulatory subunit 1B
       K06269  PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
       K05870  CREB1; cyclic AMP-responsive element-binding protein 1
       K09048  CREB3; cyclic AMP-responsive element-binding protein 3
       K09047  CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
       K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
       K04355  BDNF; brain-derived neurotrophic factor
       K04379  FOS; proto-oncogene protein c-fos
       K04448  JUN; transcription factor AP-1
       K06230  GLI3; zinc finger protein GLI3
       K16797  GLI1; zinc finger protein GLI1
       K06225  PTCH1; patched 1
       K06231  HHIP; hedgehog interacting protein
       K04734  NFKBIA; NF-kappa-B inhibitor alpha
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04735  RELA; transcription factor p65
       K18435  SOX9; transcription factor SOX9 (SOX group E)
       K04665  AMH; anti-mullerian hormone
       K07294  NR1C1, PPARA; peroxisome proliferator-activated receptor alpha
       K00232  E1.3.3.6, ACOX1, ACOX3; acyl-CoA oxidase [EC:1.3.3.6]
       K04446  NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
       K03914  F2R, PAR1; coagulation factor II (thrombin) receptor
       K02158  BAD; Bcl-2-antagonist of cell death
       K07188  LIPE, HSL; hormone-sensitive lipase [EC:3.1.1.79]
       K04514  ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
       K17388  ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
       K06270  PPP1R12A, MYPT1; protein phosphatase 1 regulatory subunit 12A
       K12755  MYL9; myosin regulatory light chain 9
       K12044  TNNI3; troponin I, cardiac muscle
       K05852  PLN; phospholamban
       K05853  ATP2A; P-type Ca2+ transporter type 2A [EC:7.2.2.10]
       K04962  RYR2; ryanodine receptor 2
       K05208  GRIN1; glutamate receptor ionotropic, NMDA 1
       K05209  GRIN2A; glutamate receptor ionotropic, NMDA 2A
       K05210  GRIN2B; glutamate receptor ionotropic, NMDA 2B
       K05211  GRIN2C; glutamate receptor ionotropic, NMDA 2C
       K05212  GRIN2D; glutamate receptor ionotropic, NMDA 2D
       K05213  GRIN3A; glutamate receptor ionotropic, NMDA 3A
       K05214  GRIN3B; glutamate receptor ionotropic, NMDA 3B
       K05197  GRIA1; glutamate receptor 1
       K05198  GRIA2; glutamate receptor 2
       K05199  GRIA3; glutamate receptor 3
       K05200  GRIA4; glutamate receptor 4
       K05031  CFTR, ABCC7; cystic fibrosis transmembrane conductance regulator [EC:5.6.1.6]
       K01539  ATP1A; sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
       K01540  ATP1B, CD298; sodium/potassium-transporting ATPase subunit beta
       K01538  FXYD2, ATP1G1; sodium/potassium-transporting ATPase subunit gamma (FXYD domain-containing ion transport regulator 2)
       K13360  FXYD1, PLM; FXYD domain-containing ion transport regulator 1
       K05742  SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
       K16056  ORAI1; calcium release-activated calcium channel protein 1
       K05850  ATP2B; P-type Ca2+ transporter type 2B [EC:7.2.2.10]
       K04850  CACNA1C, CAV1.2; voltage-dependent calcium channel L type alpha-1C
       K04851  CACNA1D, CAV1.3; voltage-dependent calcium channel L type alpha-1D
       K04853  CACNA1F, CAV1.4; voltage-dependent calcium channel L type alpha-1F
       K04857  CACNA1S, CAV1.1; voltage-dependent calcium channel L type alpha-1S
       K19021  PDE3A; cGMP-inhibited 3',5'-cyclic phosphodiesterase A [EC:3.1.4.17]
       K13296  PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B [EC:3.1.4.17]
       K13293  PDE4; cAMP-specific phosphodiesterase 4 [EC:3.1.4.53]
       K18438  PDE10; cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10 [EC:3.1.4.17 3.1.4.35]
     04022 cGMP-PKG signaling pathway [PATH:ko04022]
     04151 PI3K-Akt signaling pathway [PATH:ko04151]
     04152 AMPK signaling pathway [PATH:ko04152]
     04150 mTOR signaling pathway [PATH:ko04150]
     04075 Plant hormone signal transduction [PATH:ko04075]
 
   09133 Signaling molecules and interaction
 
 09140 Cellular Processes
 
 09150 Organismal Systems
 
   09151 Immune system
 
   09152 Endocrine system
 
   09153 Circulatory system
 
   09154 Digestive system
 
   09155 Excretory system
 
   09156 Nervous system
 
   09157 Sensory system
 
   09158 Development and regeneration
     04320 Dorso-ventral axis formation [PATH:ko04320]
     04360 Axon guidance [PATH:ko04360]
       K07522  NTNG1; netrin-G1
       K16359  NTNG2; netrin-G2
       K07523  LRRC4C, NGL1; netrin-G1 ligand
       K16351  LRRC4, NGL2; netrin-G2 ligand
       K06843  NTN1; netrin 1
       K06844  NTN3; netrin 3
       K06845  NTN4; netrin 4
       K06765  DCC; deleted in colorectal carcinoma
       K01116  PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
       K05859  PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
       K04964  TRPC1; transient receptor potential cation channel subfamily C member 1
       K04966  TRPC3; transient receptor potential cation channel subfamily C member 3
       K04967  TRPC4; transient receptor potential cation channel subfamily C member 4
       K04968  TRPC5; transient receptor potential cation channel subfamily C member 5
       K04969  TRPC6; transient receptor potential cation channel subfamily C member 6
       K04348  PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
       K06268  PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
       K17332  NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
       K17333  NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
       K17334  NFATC4, NFAT3; nuclear factor of activated T-cells, cytoplasmic 4
       K05725  PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
       K05703  FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
       K05704  SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
       K04392  RAC1; Ras-related C3 botulinum toxin substrate 1
       K07860  RAC2; Ras-related C3 botulinum toxin substrate 2
       K07861  RAC3; Ras-related C3 botulinum toxin substrate 3
       K04393  CDC42; cell division control protein 42
       K07520  ABLIM; actin-binding LIM protein
       K07365  NCK1; NCK adaptor protein 1
       K04409  PAK1; p21-activated kinase 1 [EC:2.7.11.1]
       K04410  PAK2; p21-activated kinase 2 [EC:2.7.11.1]
       K05733  PAK3, MRX30; p21-activated kinase 3 [EC:2.7.11.1]
       K05734  PAK4; p21-activated kinase 4 [EC:2.7.11.1]
       K05736  PAK5, PAK7; p21-activated kinase 5 [EC:2.7.11.1]
       K05735  PAK6; p21-activated kinase 6 [EC:2.7.11.1]
       K04513  RHOA; Ras homolog gene family, member A
       K04514  ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
       K17388  ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
       K07521  UNC5; netrin receptor unc-5
       K07293  PTPN11, SHP2; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
       K23096  RGMA; repulsive guidance molecule A
       K06766  NEO1; neogenin
       K12753  MYL5; myosin regulatory light chain 5
       K12755  MYL9; myosin regulatory light chain 9
       K12757  MYL12; myosin regulatory light chain 12
       K07532  ARHGEF12, LARG; Rho guanine nucleotide exchange factor 12
       K24609  LRIG2; leucine-rich repeats and immunoglobulin-like domains protein 2
       K05462  EFNA; ephrin-A
       K05463  EFNB; ephrin-B
       K05102  EPHA1, EPH; Eph receptor A1 [EC:2.7.10.1]
       K05103  EPHA2, ECK; Eph receptor A2 [EC:2.7.10.1]
       K05104  EPHA3, HEK, TYRO4; Eph receptor A3 [EC:2.7.10.1]
       K05105  EPHA4, SEK, TYRO1; Eph receptor A4 [EC:2.7.10.1]
       K05106  EPHA5, EHK1, TYRO4; Eph receptor A5 [EC:2.7.10.1]
       K05107  EPHA6, EHK2; Eph receptor A6 [EC:2.7.10.1]
       K05108  EPHA7, EHK3, HEK11; EphA7 [EC:2.7.10.1]
       K05109  EPHA8, EEK; Eph receptor A8 [EC:2.7.10.1]
       K05110  EPHB1, ELK, NET; Eph receptor B1 [EC:2.7.10.1]
       K05111  EPHB2, ERK, DRT; Eph receptor B2 [EC:2.7.10.1]
       K05112  EPHB3, HEK2, ETK2; Eph receptor B3 [EC:2.7.10.1]
       K05113  EPHB4, HTK; Eph receptor B4 [EC:2.7.10.1]
       K05114  EPHB6; Eph receptor B6 [EC:2.7.10.1]
       K06619  ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
       K05746  ENAH, MENA; enabled
       K04352  RASA1, RASGAP; Ras GTPase-activating protein 1
       K07525  NGEF, EPHEXIN, ARHGEF27; neuronal guanine nucleotide exchange factor
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K19862  NCK2, GRB4; NCK adaptor protein 2
       K07524  RGS3; regulator of G-protein signalling 3
       K10031  CXCL12; C-X-C motif chemokine 12
       K04189  CXCR4, CD184; C-X-C chemokine receptor type 4
       K04630  GNAI; guanine nucleotide-binding protein G(i) subunit alpha
       K06838  SLIT1; slit 1
       K06839  SLIT2; slit 2
       K06850  SLIT3; slit 3
       K06753  ROBO1; roundabout, axon guidance receptor 1
       K06754  ROBO2; roundabout, axon guidance receptor 2
       K06755  ROBO3; roundabout, axon guidance receptor 3
       K07526  SRGAP; SLIT-ROBO Rho GTPase activating protein
       K06840  SEMA3; semaphorin 3
       K06820  PLXNA; plexin A
       K06724  NRP1, CD304; neuropilin 1
       K06550  L1CAM, CD171; L1 cell adhesion molecule
       K05743  LIMK1; LIM domain kinase 1 [EC:2.7.11.1]
       K05744  LIMK2; LIM domain kinase 2 [EC:2.7.11.1]
       K05765  CFL; cofilin
       K07530  RHOD; Ras homolog gene family, member D
       K07531  RND1; Rho family GTPase 1
       K07527  FES, FPS; tyrosine-protein kinase Fes/Fps [EC:2.7.10.2]
       K07529  DPYSL5, CRAM; dihydropyrimidinase-like 5
       K07528  DPYSL2, CRMP2; dihydropyrimidinase-like 2
       K02090  CDK5; cyclin-dependent kinase 5 [EC:2.7.11.22]
       K03083  GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
       K06521  SEMA4, CD100; semaphorin 4
       K06841  SEMA5; semaphorin 5
       K06842  SEMA6; semaphorin 6
       K06821  PLXNB; plexin B
       K05099  MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K07829  RRAS; Ras-related protein R-Ras
       K06529  SEMA7, CD108; semaphorin 7
       K06572  PLXNC, CD232; plexin C
       K05719  ITGB1, CD29; integrin beta 1
       K11988  SHH; sonic hedgehog
       K06225  PTCH1; patched 1
       K06226  SMO; smoothened
       K02677  PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
       K06272  ILK; integrin-linked kinase [EC:2.7.11.1]
       K20020  BOC; brother of CDO
       K00444  WNT5; wingless-type MMTV integration site family, member 5
       K02329  FZD3; frizzled 3
       K05128  RYK; RYK receptor-like tyrosine kinase [EC:2.7.10.1]
       K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
       K00408  WNT4; wingless-type MMTV integration site family, member 4
       K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
       K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
       K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
       K04237  PARD3; partitioning defective protein 3
       K18952  PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
       K06093  PARD6; partitioning defective protein 6
       K05766  SSH; protein phosphatase slingshot [EC:3.1.3.16 3.1.3.48]
       K16621  BMP7; bone morphogenetic protein 7
       K20013  GDF7; growth differentiation factor 7
       K04671  BMPR2; bone morphogenetic protein receptor type-2 [EC:2.7.11.30]
       K13578  BMPR1B, ALK6, CDw293; bone morphogenetic protein receptor type-1B [EC:2.7.11.30]
     04361 Axon regeneration [PATH:ko04361]
     04380 Osteoclast differentiation [PATH:ko04380]
 
   09149 Aging
 
   09159 Environmental adaptation
 
 09160 Human Diseases
 
   09161 Cancer: overview
     05200 Pathways in cancer [PATH:ko05200]
       K06765  DCC; deleted in colorectal carcinoma
       K02187  CASP3; caspase 3 [EC:3.4.22.56]
       K04399  CASP9; caspase 9 [EC:3.4.22.62]
       K08733  APPL1, DIP13A; DCC-interacting protein 13 alpha
       K05689  CDH1, CDHE, CD324; cadherin 1, type 1, E-cadherin
       K02105  CTNNB1; catenin beta 1
       K05691  CTNNA; catenin alpha
       K02157  AXIN1; axin 1
       K04385  AXIN2; axin 2
       K02085  APC; adenomatosis polyposis coli protein
       K03083  GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
       K02620  TCF7, TCF-1; transcription factor 7
       K04490  TCF7L1; transcription factor 7-like 1
       K04491  TCF7L2; transcription factor 7-like 2
       K04492  LEF1; lymphoid enhancer-binding factor 1
       K08731  BIRC5; baculoviral IAP repeat-containing protein 5
       K04377  MYC; Myc proto-oncogene protein
       K04503  CCND1; G1/S-specific cyclin-D1
       K03209  WNT1; wingless-type MMTV integration site family, member 1
       K00182  WNT2; wingless-type MMTV integration site family, member 2
       K00312  WNT3; wingless-type MMTV integration site family, member 3
       K00408  WNT4; wingless-type MMTV integration site family, member 4
       K00444  WNT5; wingless-type MMTV integration site family, member 5
       K00445  WNT6; wingless-type MMTV integration site family, member 6
       K00572  WNT7; wingless-type MMTV integration site family, member 7
       K00714  WNT8; wingless-type MMTV integration site family, member 8
       K01064  WNT9; wingless-type MMTV integration site family, member 9
       K01357  WNT10; wingless-type MMTV integration site family, member 10
       K01384  WNT11; wingless-type MMTV integration site family, member 11
       K01558  WNT16; wingless-type MMTV integration site family, member 16
       K02432  FZD1_7, fz; frizzled 1/7
       K02235  FZD2; frizzled 2
       K02329  FZD3; frizzled 3
       K02354  FZD4, fz4, CD344; frizzled 4
       K02375  FZD5_8, fz2; frizzled 5/8
       K02376  FZD6; frizzled 6
       K02842  FZD9_10, CD349_50; frizzled 9/10
       K03068  LRP5_6; low density lipoprotein receptor-related protein 5/6
       K02353  DVL; segment polarity protein dishevelled
       K03069  FRAT1; frequently rearranged in advanced T-cell lymphomas 1
       K03096  FRAT2; frequently rearranged in advanced T-cell lymphomas 2
       K01313  F2; coagulation factor II (thrombin) [EC:3.4.21.5]
       K09821  AGT, SERPINA8; angiotensinogen
       K03914  F2R, PAR1; coagulation factor II (thrombin) receptor
       K04236  F2RL3, PAR4; coagulation factor II (thrombin) receptor-like 3
       K04289  LPAR1, EDG2; lysophosphatidic acid receptor 1
       K04291  LPAR2, EDG4; lysophosphatidic acid receptor 2
       K04294  LPAR3, EDG7; lysophosphatidic acid receptor 3
       K04275  LPAR4, GPR23; lysophosphatidic acid receptor 4
       K08390  LPAR5, GPR92; lysophosphatidic acid receptor 5
       K04273  LPAR6, P2RY5; lysophosphatidic acid receptor 6
       K04166  AGTR1; angiotensin II receptor type 1
       K04346  GNA12; guanine nucleotide-binding protein subunit alpha-12
       K04639  GNA13; guanine nucleotide-binding protein subunit alpha-13
       K07532  ARHGEF12, LARG; Rho guanine nucleotide exchange factor 12
       K12331  ARHGEF11; Rho guanine nucleotide exchange factor 11
       K12330  ARHGEF1; Rho guanine nucleotide exchange factor 1
       K19464  PLEKHG5; pleckstrin homology domain-containing family G member 5
       K04513  RHOA; Ras homolog gene family, member A
       K04514  ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
       K17388  ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
       K10031  CXCL12; C-X-C motif chemokine 12
       K04189  CXCR4, CD184; C-X-C chemokine receptor type 4
       K04630  GNAI; guanine nucleotide-binding protein G(i) subunit alpha
       K04258  PTGER1; prostaglandin E receptor 1
       K04259  PTGER2; prostaglandin E receptor 2
       K04260  PTGER3; prostaglandin E receptor 3
       K04261  PTGER4; prostaglandin E receptor 4
       K04632  GNAS; guanine nucleotide-binding protein G(s) subunit alpha
       K08041  ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
       K08042  ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
       K08043  ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
       K08044  ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
       K08045  ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
       K08046  ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
       K08047  ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
       K08048  ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
       K08049  ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K04536  GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
       K04537  GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
       K07825  GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
       K04538  GNB4; guanine nucleotide-binding protein subunit beta-4
       K04539  GNB5; guanine nucleotide-binding protein subunit beta-5
       K07826  GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
       K04540  GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
       K04541  GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
       K04542  GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
       K04543  GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
       K04544  GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
       K04545  GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
       K04546  GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
       K04347  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
       K04547  GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
       K04548  GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
       K04549  GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
       K06237  COL4A; collagen type IV alpha
       K05637  LAMA1_2; laminin, alpha 1/2
       K06240  LAMA3_5; laminin, alpha 3/5
       K06241  LAMA4; laminin, alpha 4
       K05636  LAMB1; laminin, beta 1
       K06243  LAMB2; laminin, beta 2
       K06244  LAMB3; laminin, beta 3
       K06245  LAMB4; laminin, beta 4
       K05635  LAMC1; laminin, gamma 1
       K06246  LAMC2; laminin, gamma 2
       K06247  LAMC3; laminin, gamma 3
       K05717  FN1; fibronectin 1
       K06481  ITGA2, CD49b; integrin alpha 2
       K06476  ITGA2B, CD41; integrin alpha 2B
       K06482  ITGA3, CD49c; integrin alpha 3
       K06485  ITGA6, CD49f; integrin alpha 6
       K06487  ITGAV, CD51; integrin alpha V
       K05719  ITGB1, CD29; integrin beta 1
       K05725  PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
       K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
       K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
       K01110  PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
       K09348  NKX3-1; homeobox protein Nkx-3.1
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
       K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
       K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
       K04734  NFKBIA; NF-kappa-B inhibitor alpha
       K02580  NFKB1; nuclear factor NF-kappa-B p105 subunit
       K04469  NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
       K04735  RELA; transcription factor p65
       K11987  PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
       K13241  NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
       K02161  BCL2; apoptosis regulator Bcl-2
       K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
       K04725  XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
       K16061  BIRC7_8; baculoviral IAP repeat-containing protein 7/8
       K04570  BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
       K03172  TRAF1; TNF receptor-associated factor 1
       K03173  TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
       K03174  TRAF3; TNF receptor-associated factor 3
       K09848  TRAF4; TNF receptor-associated factor 4
       K09849  TRAF5; TNF receptor-associated factor 5
       K03175  TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
       K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
       K04688  RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
       K02158  BAD; Bcl-2-antagonist of cell death
       K07201  FOXO1; forkhead box protein O1
       K06643  MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
       K04451  TP53, P53; tumor protein p53
       K06624  CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
       K06625  CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
       K08878  BCR1, BCR; breakpoint cluster region protein [EC:2.7.11.1]
       K06619  ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
       K04438  CRK, CRKII; C-crk adapter molecule crk
       K04707  CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
       K11223  STAT5A; signal transducer and activator of transcription 5A
       K11224  STAT5B; signal transducer and activator of transcription 5B
       K04702  PIM1; proto-oncogene serine/threonine-protein kinase Pim-1 [EC:2.7.11.1]
       K08806  PIM2; proto-oncogene serine/threonine-protein kinase Pim-2 [EC:2.7.11.1]
       K03898  KNG, BK; kininogen
       K16366  EDN1; endothelin-1
       K03915  BDKRB1; bradykinin receptor B1
       K03916  BDKRB2; bradykinin receptor B2
       K04197  EDNRA; endothelin receptor type A
       K04198  EDNRB; endothelin receptor type B
       K04634  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
       K04635  GNA11; guanine nucleotide-binding protein subunit alpha-11
       K05858  PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
       K02677  PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
       K19662  PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
       K19663  PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
       K05429  IL2; interleukin 2
       K04736  IL3; interleukin 3
       K05430  IL4; interleukin 4
       K05428  IL5; interleukin 5
       K05405  IL6; interleukin 6
       K05431  IL7; interleukin 7
       K05406  IL12A; interleukin 12A
       K05425  IL12B; interleukin 12B
       K05435  IL13; interleukin 13
       K05433  IL15; interleukin 15
       K05426  IL23A; interleukin 23 subunit alpha
       K05437  EPO; erythropoietin
       K05414  IFNA; interferon alpha
       K04687  IFNG; interferon gamma
       K05068  IL2RA, CD25; interleukin 2 receptor alpha
       K05069  IL2RB, CD122; interleukin 2 receptor beta
       K05070  IL2RG, CD132; interleukin 2 receptor gamma
       K04737  IL3RA, CD123; interleukin 3 receptor alpha
       K05071  IL4R, CD124; interleukin 4 receptor
       K04738  CSF2RB, IL3RB, CD131; cytokine receptor common subunit beta
       K05067  IL5RA, CD125; interleukin 5 receptor alpha
       K05055  IL6R, CD126; interleukin 6 receptor
       K05060  IL6ST, GP130, CD130; interleukin 6 signal transducer
       K05072  IL7R, CD127; interleukin 7 receptor
       K05063  IL12RB1, CD212; interleukin 12 receptor beta-1
       K05064  IL12RB2; interleukin 12 receptor beta-2
       K05076  IL13RA1, CD213A1; interleukin 13 receptor alpha-1
       K05074  IL15RA, CD215; interleukin 15 receptor alpha
       K05065  IL23R; interleukin 23 receptor
       K05079  EPOR; erythropoietin receptor
       K05130  IFNAR1; interferon receptor 1
       K05131  IFNAR2; interferon receptor 2
       K05132  IFNGR1, CD119; interferon gamma receptor 1
       K05133  IFNGR2; interferon gamma receptor 2
       K15420  EML4; echinoderm microtubule-associated protein-like 4
       K05119  ALK, CD246; anaplastic lymphoma kinase [EC:2.7.10.1]
       K04350  RASGRP1; RAS guanyl-releasing protein 1
       K12361  RASGRP2; RAS guanyl-releasing protein 2
       K12362  RASGRP3; RAS guanyl-releasing protein 3
       K12363  RASGRP4; RAS guanyl-releasing protein 4
       K11217  JAK1; Janus kinase 1 [EC:2.7.10.2]
       K04447  JAK2; Janus kinase 2 [EC:2.7.10.2]
       K11218  JAK3; Janus kinase 3 [EC:2.7.10.2]
       K04692  STAT3; signal transducer and activator of transcription 3
       K11220  STAT1; signal transducer and activator of transcription 1
       K11221  STAT2; signal transducer and activator of transcription 2
       K11222  STAT4; signal transducer and activator of transcription 4
       K11225  STAT6; signal transducer and activator of transcription 6
       K05448  VEGFA; vascular endothelial growth factor A
       K16858  VEGFB; vascular endothelial growth factor B
       K16859  PGF; placenta growth factor
       K05449  VEGFC_D; vascular endothelial growth factor C/D
       K08774  TGFA; transforming growth factor, alpha
       K04357  EGF; epidermal growth factor
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K05083  ERBB2, HER2, CD340; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
       K04359  PDGFA; platelet-derived growth factor subunit A
       K17386  PDGFB; platelet-derived growth factor subunit B
       K04363  PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
       K05089  PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
       K05459  IGF1; insulin-like growth factor 1
       K13769  IGF2; insulin-like growth factor 2
       K05087  IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
       K05461  KITLG; KIT ligand
       K05091  KIT, SCFR, CD117; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
       K05454  FLT3LG; fms-related tyrosine kinase 3 ligand
       K05092  FLT3, FLK2, CD135; fms-related tyrosine kinase 3 [EC:2.7.10.1]
       K05460  HGF; hepatocyte growth factor
       K05099  MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
       K18496  FGF1; fibroblast growth factor 1
       K18497  FGF2; fibroblast growth factor 2
       K04358  FGF; fibroblast growth factor
       K22603  FGF19; fibroblast growth factor 19
       K22429  FGF21; fibroblast growth factor 21
       K22428  FGF23; fibroblast growth factor 23
       K04362  FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
       K05093  FGFR2, CD332; fibroblast growth factor receptor 2 [EC:2.7.10.1]
       K05094  FGFR3, CD333; fibroblast growth factor receptor 3 [EC:2.7.10.1]
       K05095  FGFR4, CD334; fibroblast growth factor receptor 4 [EC:2.7.10.1]
       K04364  GRB2; growth factor receptor-bound protein 2
       K03099  SOS; son of sevenless
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K08845  ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04365  BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04448  JUN; transcription factor AP-1
       K04379  FOS; proto-oncogene protein c-fos
       K02678  ETS1, pnt; C-ets-1
       K01388  MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
       K01398  MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
       K01403  MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
       K10030  IL8, CXCL8; interleukin 8
       K02089  CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
       K04445  RPS6KA5, MSK1; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
       K05126  RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
       K09288  CCDC6, PTC; coiled-coil domain-containing protein 6
       K09289  NCOA4, PTC3; nuclear receptor coactivator 4
       K03176  NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
       K09290  TPM3; tropomyosin 3
       K09291  TPR, MLP1, MLP2; nucleoprotein TPR
       K09292  TFG; protein TFG
       K09850  RASSF1; Ras association domain-containing protein 1
       K08015  RASSF5, RAPL; Ras association domain-containing protein 5
       K04411  STK4, MST1; serine/threonine kinase 4
       K08803  DAPK; death-associated protein kinase [EC:2.7.11.1]
       K01116  PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
       K05859  PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
       K04375  ELK1; ETS domain-containing protein Elk-1
       K02183  CALM; calmodulin
       K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
       K08732  RALGDS; ral guanine nucleotide dissociation stimulator
       K07834  RALA; Ras-related protein Ral-A
       K07835  RALB; Ras-related protein Ral-B
       K08773  RALBP1; RalA-binding protein 1
       K04393  CDC42; cell division control protein 42
       K04392  RAC1; Ras-related C3 botulinum toxin substrate 1
       K07860  RAC2; Ras-related C3 botulinum toxin substrate 2
       K07861  RAC3; Ras-related C3 botulinum toxin substrate 3
       K01115  PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
       K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
       K09293  PAX8; paired box protein 8
       K08530  NR1C3, PPARG; peroxisome proliferator-activated receptor gamma
       K08524  RXRA, NR2B1; retinoid X receptor alpha
       K08525  RXRB, NR2B2; retinoid X receptor beta
       K08526  RXRG, NR2B3; retinoid X receptor gamma
       K08528  RARB, NR1B2; retinoic acid receptor beta
       K08550  ESR1, NR3A1; estrogen receptor alpha
       K08551  ESR2, NR3A2; estrogen receptor beta
       K09101  NCOA1, SRC1, KAT13A; nuclear receptor coactivator 1 [EC:2.3.1.48]
       K11256  NCOA3, ACTR, KAT13B; nuclear receptor coactivator 3 [EC:2.3.1.48]
       K04684  SP1; transcription factor Sp1
       K04504  NR1C2, PPARD; peroxisome proliferator-activated receptor delta
       K10056  JUP, PG; junction plakoglobin
       K10055  ZBTB16, PLZF; zinc finger and BTB domain-containing protein 16
       K08527  RARA, NR1B1; retinoic acid receptor alpha
       K06627  CCNA; cyclin-A
       K10054  PML, TRIM19; E3 SUMO-protein ligase PML [EC:2.3.2.-]
       K08367  RUNX1, AML1; runt-related transcription factor 1
       K10053  RUNX1T1, CBFA2T1; CBFA2/RNUX1 translocation partner 1
       K09438  SPI1; transcription factor PU.1
       K09055  CEBPA; CCAAT/enhancer binding protein (C/EBP), alpha
       K05066  CSF2RA, GMCSFR, CD116; granulocyte-macrophage colony-stimulating factor receptor alpha
       K05061  CSF3R, CD114; granulocyte colony-stimulating factor receptor
       K05090  CSF1R, FMS, CD115; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
       K06621  CDKN2A, P16, INK4A; cyclin-dependent kinase inhibitor 2A
       K17454  E2F1; transcription factor E2F1
       K09389  E2F2; transcription factor E2F2
       K06620  E2F3; transcription factor E2F3
       K04453  MAX; Max protein
       K10500  ZBTB17, MIZ1; zinc finger and BTB domain-containing protein 17
       K04685  CDKN2B, P15, INK4B; cyclin-dependent kinase inhibitor 2B
       K02091  CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
       K10151  CCND2; G1/S-specific cyclin-D2
       K10152  CCND3; G1/S-specific cyclin-D3
       K02219  CKS1; cyclin-dependent kinase regulatory subunit CKS1
       K03094  SKP1, CBF3D; S-phase kinase-associated protein 1
       K03347  CUL1, CDC53; cullin 1
       K03868  RBX1, ROC1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
       K03875  SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
       K02206  CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
       K06626  CCNE; G1/S-specific cyclin-E1
       K06618  RB1; retinoblastoma-associated protein
       K04402  GADD45; growth arrest and DNA-damage-inducible protein
       K02159  BAX; apoptosis regulator BAX
       K14021  BAK, BAK1; Bcl-2 homologous antagonist/killer
       K10140  DDB2; DNA damage-binding protein 2
       K03511  POLK; DNA polymerase kappa [EC:2.7.7.7]
       K11126  TERT, EST2; telomerase reverse transcriptase [EC:2.7.7.49]
       K22183  TERC; telomerase RNA component
       K09455  MITF; microphthalmia-associated transcription factor
       K13375  TGFB1; transforming growth factor beta-1
       K13376  TGFB2; transforming growth factor beta-2
       K13377  TGFB3; transforming growth factor beta-3
       K04674  TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
       K04388  TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
       K04500  SMAD2; mothers against decapentaplegic homolog 2
       K23605  SMAD3; mothers against decapentaplegic homolog 3
       K04501  SMAD4; mothers against decapentaplegic homolog 4
       K04462  MECOM, EVI1, PRDM3; [histone H3]-lysine9 N-methyltransferase (ecotropic virus integration site 1 protein) [EC:2.1.1.367]
       K04496  CTBP; C-terminal binding protein [EC:1.1.1.428]
       K06067  HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
       K08734  MLH1; DNA mismatch repair protein MLH1
       K08735  MSH2; DNA mismatch repair protein MSH2
       K08736  MSH3; DNA mismatch repair protein MSH3
       K08737  MSH6; DNA mismatch repair protein MSH6
       K08775  BRCA2, FANCD1; breast cancer 2 susceptibility protein
       K04482  RAD51; DNA repair protein RAD51
       K04389  TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
       K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
       K02373  FADD; FAS-associated death domain protein
       K04398  CASP8; caspase 8 [EC:3.4.22.61]
       K04726  BID; BH3 interacting domain death agonist
       K10131  PMAIP1, NOXA; phorbol-12-myristate-13-acetate-induced protein 1
       K10132  BBC3, PUMA; Bcl-2-binding component 3
       K16341  BCL2L11, BIM; Bcl-2-like protein 11
       K08738  CYC; cytochrome c
       K02084  APAF1; apoptotic protease-activating factor
       K04397  CASP7; caspase 7 [EC:3.4.22.60]
       K10456  KLHL19, KEAP1, INRF2; kelch-like protein 19
       K05638  NFE2L2, NRF2; nuclear factor erythroid 2-related factor 2
       K00510  HMOX1; heme oxygenase 1 [EC:1.14.14.18]
       K00355  NQO1; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]
       K00799  GST, gst; glutathione S-transferase [EC:2.5.1.18]
       K23790  GSTP; glutathione S-transferase P [EC:2.5.1.18]
       K22182  TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
       K03871  VHL; von Hippel-Lindau disease tumor supressor
       K03872  ELOC, TCEB1; elongin-C
       K03873  ELOB, TCEB2; elongin-B
       K03870  CUL2; cullin 2
       K09592  EGLN, HPH; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
       K01679  E4.2.1.2B, fumC, FH; fumarate hydratase, class II [EC:4.2.1.2]
       K08268  HIF1A; hypoxia-inducible factor 1 alpha
       K09095  HIF2A, EPAS1; hypoxia-inducible factor 2 alpha
       K09097  ARNT; aryl hydrocarbon receptor nuclear translocator
       K15589  ARNT2; aryl hydrocarbon receptor nuclear translocator 2
       K04498  EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
       K07299  SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
       K06052  JAG1, CD339; jagged-1
       K21635  JAG2; jagged-2
       K06051  DLL; delta
       K02599  NOTCH1; Notch 1
       K20994  NOTCH2; Notch 2
       K20995  NOTCH3; Notch 3
       K20996  NOTCH4; Notch 4
       K06054  HES1; hairy and enhancer of split 1
       K06055  HES5; hairy and enhancer of split 5
       K09091  HEY; hairy and enhancer of split related with YRPW motif
       K05097  FLT4, VEGFR3; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
       K11988  SHH; sonic hedgehog
       K06225  PTCH1; patched 1
       K06226  SMO; smoothened
       K18806  KIF7; kinesin family member 7
       K06229  SUFU; suppressor of fused
       K16797  GLI1; zinc finger protein GLI1
       K16798  GLI2; zinc finger protein GLI2
       K06230  GLI3; zinc finger protein GLI3
       K21283  BMP2; bone morphogenetic protein 2
       K04662  BMP4; bone morphogenetic protein 4
       K06231  HHIP; hedgehog interacting protein
       K11101  PTCH2; patched 2
       K08557  AR, NR3C4; androgen receptor
       K04079  HSP90A, htpG; molecular chaperone HtpG
       K09487  HSP90B, TRA1; heat shock protein 90kDa beta
       K01351  KLK3, PSA; semenogelase [EC:3.4.21.77]
     05202 Transcriptional misregulation in cancer [PATH:ko05202]
     05206 MicroRNAs in cancer [PATH:ko05206]
     05205 Proteoglycans in cancer [PATH:ko05205]
       K06256  CD44; CD44 antigen
       K05704  SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
       K06106  CTTN, EMS1; cortactin
       K05083  ERBB2, HER2, CD340; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
       K04364  GRB2; growth factor receptor-bound protein 2
       K05730  VAV; guanine nucleotide exchange factor VAV
       K02833  HRAS; GTPase HRas
       K07827  KRAS, KRAS2; GTPase KRas
       K07828  NRAS; GTPase NRas
       K07829  RRAS; Ras-related protein R-Ras
       K07830  RRAS2, TC21; Ras-related protein R-Ras2
       K07831  MRAS; Ras-related protein M-Ras
       K04365  BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04366  RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K08845  ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
       K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
       K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
       K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
       K04392  RAC1; Ras-related C3 botulinum toxin substrate 1
       K16848  IQGAP1; Ras GTPase-activating-like protein IQGAP1
       K04393  CDC42; cell division control protein 42
       K04375  ELK1; ETS domain-containing protein Elk-1
       K08550  ESR1, NR3A1; estrogen receptor alpha
       K04503  CCND1; G1/S-specific cyclin-D1
       K05692  ACTB_G1; actin beta/gamma 1
       K04437  FLNA; filamin-A
       K04409  PAK1; p21-activated kinase 1 [EC:2.7.11.1]
       K05731  TIAM1; T-lymphoma invasion and metastasis-inducing protein 1
       K12330  ARHGEF1; Rho guanine nucleotide exchange factor 1
       K04513  RHOA; Ras homolog gene family, member A
       K04514  ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
       K17388  ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
       K10380  ANK1; ankyrin-1
       K09255  ANK2, ANKB; ankyrin-2
       K09259  ANK3, ANKG; ankyrin-3
       K09593  GAB1; GRB2-associated-binding protein 1
       K00922  PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
       K02649  PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
       K04456  AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
       K05742  SLC9A1, NHE1; solute carrier family 9 (sodium/hydrogen exchanger), member 1
       K06269  PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
       K06270  PPP1R12A, MYPT1; protein phosphatase 1 regulatory subunit 12A
       K12329  PPP1R12B, MYPT2; protein phosphatase 1 regulatory subunit 12B
       K17457  PPP1R12C, MBS85; protein phosphatase 1 regulatory subunit 12C
       K07532  ARHGEF12, LARG; Rho guanine nucleotide exchange factor 12
       K05860  PLCE; phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
       K04958  ITPR1; inositol 1,4,5-triphosphate receptor type 1
       K04959  ITPR2; inositol 1,4,5-triphosphate receptor type 2
       K04960  ITPR3; inositol 1,4,5-triphosphate receptor type 3
       K04515  CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
       K10164  NANOG; homeobox protein Nanog
       K12823  DDX5, DBP2; ATP-dependent RNA helicase DDX5/DBP2 [EC:5.6.2.7]
       K03685  rnc, DROSHA, RNT1; ribonuclease III [EC:3.1.26.3]
       K04692  STAT3; signal transducer and activator of transcription 3
       K16863  MIR21; microRNA 21
       K09069  TWIST; twist
       K16864  MIR10A; microRNA 10a
       K17393  MIR10B; microRNA 10b
       K09295  HOXD10; homrobox protein Hox-D10
       K04660  DCN; decorin
       K05459  IGF1; insulin-like growth factor 1
       K05087  IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
       K07203  MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
       K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
       K04688  RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
       K03258  EIF4B; translation initiation factor 4B
       K02991  RP-S6e, RPS6; small subunit ribosomal protein S6e
       K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
       K06278  CAV1; caveolin 1
       K12958  CAV2; caveolin 2
       K12959  CAV3; caveolin 3
       K06497  CD63, MLA1, TSPAN30; CD63 antigen
       K06625  CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
       K02187  CASP3; caspase 3 [EC:3.4.22.56]
       K13375  TGFB1; transforming growth factor beta-1
       K10159  TLR2, CD282; toll-like receptor 2
       K10160  TLR4, CD284; toll-like receptor 4
       K16865  PDCD4; programmed cell death protein 4
       K03156  TNF, TNFA; tumor necrosis factor superfamily, member 2
       K05425  IL12B; interleukin 12B
       K05084  ERBB3, HER3; receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1]
       K05085  ERBB4, HER4; receptor tyrosine-protein kinase erbB-4 [EC:2.7.10.1]
       K04377  MYC; Myc proto-oncogene protein
       K02105  CTNNB1; catenin beta 1
       K08268  HIF1A; hypoxia-inducible factor 1 alpha
       K09108  TFAP4; transcription factor AP-4
       K05448  VEGFA; vascular endothelial growth factor A
       K05098  KDR, VEGFR2, CD309; kinase insert domain protein receptor [EC:2.7.10.1]
       K05099  MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
       K04707  CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
       K16866  TIMP3; metalloproteinase inhibitor 3
       K16857  THBS1; thrombospondin 1
       K01398  MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
       K01403  MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
       K08122  LUM; lumican
       K04389  TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
       K04390  TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
       K06643  MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
       K04451  TP53, P53; tumor protein p53
       K13376  TGFB2; transforming growth factor beta-2
       K04500  SMAD2; mothers against decapentaplegic homolog 2
       K07964  HPSE; heparanase [EC:3.2.1.166]
       K07965  HPSE2; heparanase 2 [EC:3.2.1.-]
       K06257  SDC1, CD138; syndecan 1
       K01348  PLAU; urokinase plasminogen activator [EC:3.4.21.73]
       K03985  PLAUR, CD87; plasminogen activator, urokinase receptor
       K06236  COL1A; collagen type I alpha
       K06481  ITGA2, CD49b; integrin alpha 2
       K05719  ITGB1, CD29; integrin beta 1
       K06251  VTN; vitronectin
       K06487  ITGAV, CD51; integrin alpha V
       K06493  ITGB3, CD61; integrin beta 3
       K05717  FN1; fibronectin 1
       K06588  ITGB5; integrin beta 5
       K05460  HGF; hepatocyte growth factor
       K03209  WNT1; wingless-type MMTV integration site family, member 1
       K02432  FZD1_7, fz; frizzled 1/7
       K02235  FZD2; frizzled 2
       K02329  FZD3; frizzled 3
       K02354  FZD4, fz4, CD344; frizzled 4
       K02375  FZD5_8, fz2; frizzled 5/8
       K02376  FZD6; frizzled 6
       K02842  FZD9_10, CD349_50; frizzled 9/10
       K06484  ITGA5, CD49e; integrin alpha 5
       K16336  SDC2, CD362; syndecan 2
       K08007  EZR, VIL2; ezrin
       K05762  RDX; radixin
       K05763  MSN; moesin
       K16338  SDC4; syndecan 4
       K18497  FGF2; fibroblast growth factor 2
       K04362  FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
       K12461  FRS2; fibroblast growth factor receptor substrate 2
       K07293  PTPN11, SHP2; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
       K03099  SOS; son of sevenless
       K01116  PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
       K05859  PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
       K02677  PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
       K19662  PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
       K19663  PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
       K16867  NUDT16L1, SDOS; NUDT16-like protein 1
       K05760  PXN; paxillin
       K05725  PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
       K08523  HBEGF; heparin-binding EGF-like growth factor
       K08107  GPC1; glypican 1
       K13769  IGF2; insulin-like growth factor 2
       K08109  GPC3; glypican 3
       K00182  WNT2; wingless-type MMTV integration site family, member 2
       K00312  WNT3; wingless-type MMTV integration site family, member 3
       K00408  WNT4; wingless-type MMTV integration site family, member 4
       K00444  WNT5; wingless-type MMTV integration site family, member 5
       K00445  WNT6; wingless-type MMTV integration site family, member 6
       K00572  WNT7; wingless-type MMTV integration site family, member 7
       K00714  WNT8; wingless-type MMTV integration site family, member 8
       K01064  WNT9; wingless-type MMTV integration site family, member 9
       K01357  WNT10; wingless-type MMTV integration site family, member 10
       K01384  WNT11; wingless-type MMTV integration site family, member 11
       K01558  WNT16; wingless-type MMTV integration site family, member 16
       K11988  SHH; sonic hedgehog
       K11989  IHH; indian hedgehog
       K06225  PTCH1; patched 1
       K06226  SMO; smoothened
       K06255  HSPG2; basement membrane-specific heparan sulfate proteoglycan core protein
       K01365  CTSL; cathepsin L [EC:3.4.22.15]
       K04345  PKA; protein kinase A [EC:2.7.11.11]
       K04441  P38; p38 MAP kinase [EC:2.7.11.24]
       K09543  HSPB2; heat shock protein beta-2
       K05697  PTPN6, SHP1; tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]
     05204 Chemical carcinogenesis - DNA adducts [PATH:ko05204]
     05207 Chemical carcinogenesis - receptor activation [PATH:ko05207]
     05208 Chemical carcinogenesis - reactive oxygen species [PATH:ko05208]
     05203 Viral carcinogenesis [PATH:ko05203]
     05230 Central carbon metabolism in cancer [PATH:ko05230]
     05231 Choline metabolism in cancer [PATH:ko05231]
     05235 PD-L1 expression and PD-1 checkpoint pathway in cancer [PATH:ko05235]
 
   09162 Cancer: specific types
     05210 Colorectal cancer [PATH:ko05210]
     05212 Pancreatic cancer [PATH:ko05212]
     05225 Hepatocellular carcinoma [PATH:ko05225]
     05226 Gastric cancer [PATH:ko05226]
     05214 Glioma [PATH:ko05214]
     05216 Thyroid cancer [PATH:ko05216]
     05221 Acute myeloid leukemia [PATH:ko05221]
     05220 Chronic myeloid leukemia [PATH:ko05220]
     05217 Basal cell carcinoma [PATH:ko05217]
       K04451  TP53, P53; tumor protein p53
       K06625  CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
       K04402  GADD45; growth arrest and DNA-damage-inducible protein
       K02159  BAX; apoptosis regulator BAX
       K14021  BAK, BAK1; Bcl-2 homologous antagonist/killer
       K10140  DDB2; DNA damage-binding protein 2
       K03511  POLK; DNA polymerase kappa [EC:2.7.7.7]
       K11988  SHH; sonic hedgehog
       K06225  PTCH1; patched 1
       K06226  SMO; smoothened
       K18806  KIF7; kinesin family member 7
       K06229  SUFU; suppressor of fused
       K16797  GLI1; zinc finger protein GLI1
       K16798  GLI2; zinc finger protein GLI2
       K06230  GLI3; zinc finger protein GLI3
       K21283  BMP2; bone morphogenetic protein 2
       K04662  BMP4; bone morphogenetic protein 4
       K06231  HHIP; hedgehog interacting protein
       K11101  PTCH2; patched 2
       K03209  WNT1; wingless-type MMTV integration site family, member 1
       K00182  WNT2; wingless-type MMTV integration site family, member 2
       K00312  WNT3; wingless-type MMTV integration site family, member 3
       K00408  WNT4; wingless-type MMTV integration site family, member 4
       K00444  WNT5; wingless-type MMTV integration site family, member 5
       K00445  WNT6; wingless-type MMTV integration site family, member 6
       K00572  WNT7; wingless-type MMTV integration site family, member 7
       K00714  WNT8; wingless-type MMTV integration site family, member 8
       K01064  WNT9; wingless-type MMTV integration site family, member 9
       K01357  WNT10; wingless-type MMTV integration site family, member 10
       K01384  WNT11; wingless-type MMTV integration site family, member 11
       K01558  WNT16; wingless-type MMTV integration site family, member 16
       K02432  FZD1_7, fz; frizzled 1/7
       K02235  FZD2; frizzled 2
       K02329  FZD3; frizzled 3
       K02354  FZD4, fz4, CD344; frizzled 4
       K02375  FZD5_8, fz2; frizzled 5/8
       K02376  FZD6; frizzled 6
       K02842  FZD9_10, CD349_50; frizzled 9/10
       K02353  DVL; segment polarity protein dishevelled
       K03083  GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
       K02157  AXIN1; axin 1
       K04385  AXIN2; axin 2
       K02085  APC; adenomatosis polyposis coli protein
       K02105  CTNNB1; catenin beta 1
       K02620  TCF7, TCF-1; transcription factor 7
       K04490  TCF7L1; transcription factor 7-like 1
       K04491  TCF7L2; transcription factor 7-like 2
       K04492  LEF1; lymphoid enhancer-binding factor 1
     05218 Melanoma [PATH:ko05218]
     05211 Renal cell carcinoma [PATH:ko05211]
     05219 Bladder cancer [PATH:ko05219]
     05215 Prostate cancer [PATH:ko05215]
     05213 Endometrial cancer [PATH:ko05213]
     05224 Breast cancer [PATH:ko05224]
     05222 Small cell lung cancer [PATH:ko05222]
     05223 Non-small cell lung cancer [PATH:ko05223]
 
   09172 Infectious disease: viral
 
   09171 Infectious disease: bacterial
 
   09174 Infectious disease: parasitic
 
   09163 Immune disease
 
   09164 Neurodegenerative disease
 
   09165 Substance dependence
 
   09166 Cardiovascular disease
 
   09167 Endocrine and metabolic disease
 
   09175 Drug resistance: antimicrobial
 
   09176 Drug resistance: antineoplastic
 
 09180 Brite Hierarchies
 
 09190 Not Included in Pathway or Brite

[ KO | BRITE | KEGG2 | KEGG ]
Last updated: May 9, 2024