KEGG   PATHWAY: mmma05200
Entry
mmma05200                   Pathway                                
Name
Pathways in cancer - Marmota marmota marmota (Alpine marmot)
Class
Human Diseases; Cancer: overview
Pathway map
mmma05200  Pathways in cancer
mmma05200

Organism
Marmota marmota marmota (Alpine marmot) [GN:mmma]
Gene
107139499  Dcc; netrin receptor DCC isoform X1 [KO:K06765]
107142678  Casp3; caspase-3 isoform X1 [KO:K02187] [EC:3.4.22.56]
107158031  caspase-3-like [KO:K02187] [EC:3.4.22.56]
107142215  Casp9; caspase-9 [KO:K04399] [EC:3.4.22.62]
107149698  Appl1; DCC-interacting protein 13-alpha isoform X1 [KO:K08733]
107151067  Cdh1; cadherin-1 [KO:K05689]
107145471  Ctnnb1; catenin beta-1 [KO:K02105]
107141385  Ctnna1; catenin alpha-1 isoform X3 [KO:K05691]
107154850  Ctnna3; catenin alpha-3 isoform X1 [KO:K05691]
107154248  Ctnna2; catenin alpha-2 isoform X2 [KO:K05691]
107146791  Axin1; axin-1 isoform X1 [KO:K02157]
107158361  Axin2; axin-2 isoform X1 [KO:K04385]
107141069  Apc; adenomatous polyposis coli protein isoform X6 [KO:K02085]
107157407  Apc2; LOW QUALITY PROTEIN: adenomatous polyposis coli protein 2 [KO:K02085]
107136282  Gsk3b; glycogen synthase kinase-3 beta isoform X1 [KO:K03083] [EC:2.7.11.26]
107148128  Tcf7; transcription factor 7 isoform X6 [KO:K02620]
107159692  Tcf7l1; transcription factor 7-like 1 isoform X1 [KO:K04490]
107149900  Tcf7l2; transcription factor 7-like 2 isoform X2 [KO:K04491]
107141378  Lef1; lymphoid enhancer-binding factor 1 isoform X7 [KO:K04492]
107147207  baculoviral IAP repeat-containing protein 5 [KO:K08731]
125610369  Birc5; baculoviral IAP repeat-containing protein 5 isoform X1 [KO:K08731]
107142789  Myc; myc proto-oncogene protein [KO:K04377]
107156886  Ccnd1; G1/S-specific cyclin-D1 [KO:K04503]
107148723  Wnt1; proto-oncogene Wnt-1 [KO:K03209]
107144491  Wnt2; protein Wnt-2 [KO:K00182]
107156150  Wnt2b; protein Wnt-2b [KO:K00182]
107160515  Wnt3; proto-oncogene Wnt-3 [KO:K00312]
107153302  Wnt3a; protein Wnt-3a [KO:K00312]
107142152  Wnt4; protein Wnt-4 [KO:K00408]
107149617  Wnt5a; LOW QUALITY PROTEIN: protein Wnt-5a [KO:K00444]
107155012  Wnt5b; protein Wnt-5b isoform X3 [KO:K00444]
107138480  Wnt6; protein Wnt-6 [KO:K00445]
107150185  protein Wnt-7a [KO:K00572]
107155744  Wnt7b; protein Wnt-7b [KO:K00572]
107141176  Wnt8a; protein Wnt-8a [KO:K00714]
107149946  Wnt8b; protein Wnt-8b [KO:K00714]
107160533  Wnt9b; protein Wnt-9b [KO:K01064]
107153234  Wnt9a; protein Wnt-9a isoform X1 [KO:K01064]
107138402  Wnt10a; protein Wnt-10a [KO:K01357]
107148595  Wnt10b; protein Wnt-10b isoform X1 [KO:K01357]
107135499  Wnt11; protein Wnt-11 isoform X1 [KO:K01384]
107144604  Wnt16; protein Wnt-16 [KO:K01558]
107138616  Fzd7; frizzled-7 [KO:K02432]
107156284  Fzd1; frizzled-1 [KO:K02432]
107150685  Fzd2; frizzled-2 [KO:K02235]
107153882  Fzd3; frizzled-3 [KO:K02329]
107156646  Fzd4; frizzled-4 [KO:K02354]
107140236  uncharacterized protein LOC107140236 [KO:K02375]
107142849  Fzd6; frizzled-6 isoform X1 [KO:K02376]
107147043  Fzd9; frizzled-9 [KO:K02842]
107159092  Fzd10; frizzled-10 [KO:K02842]
107152668  Lrp6; low-density lipoprotein receptor-related protein 6 isoform X1 [KO:K03068]
107157026  Lrp5; low-density lipoprotein receptor-related protein 5 isoform X2 [KO:K03068]
107155457  Dvl1; segment polarity protein dishevelled homolog DVL-1 [KO:K02353]
107154316  Dvl3; segment polarity protein dishevelled homolog DVL-3 [KO:K02353]
107157968  Dvl2; segment polarity protein dishevelled homolog DVL-2 isoform X1 [KO:K02353]
107149936  Frat1; LOW QUALITY PROTEIN: proto-oncogene FRAT1 [KO:K03069]
107149939  Frat2; GSK-3-binding protein FRAT2 [KO:K03096]
107135800  F2; prothrombin isoform X2 [KO:K01313] [EC:3.4.21.5]
107157900  Agt; angiotensinogen [KO:K09821]
107152260  F2r; proteinase-activated receptor 1 [KO:K03914]
107134437  F2rl3; proteinase-activated receptor 4 [KO:K04236]
107147705  Lpar1; lysophosphatidic acid receptor 1 isoform X1 [KO:K04289]
107145387  Lpar2; lysophosphatidic acid receptor 2 [KO:K04291]
107158249  Lpar3; lysophosphatidic acid receptor 3 [KO:K04294]
107156082  Lpar4; lysophosphatidic acid receptor 4 [KO:K04275]
107154955  Lpar5; lysophosphatidic acid receptor 5 [KO:K08390]
107141037  Lpar6; lysophosphatidic acid receptor 6 [KO:K04273]
107143327  Agtr1; type-1 angiotensin II receptor [KO:K04166]
107155972  guanine nucleotide-binding protein subunit alpha-12 [KO:K04346]
107158364  Gna13; guanine nucleotide-binding protein subunit alpha-13 [KO:K04639]
107145661  Arhgef12; rho guanine nucleotide exchange factor 12 [KO:K07532]
107156669  Arhgef11; rho guanine nucleotide exchange factor 11 isoform X7 [KO:K12331]
107151403  Arhgef1; rho guanine nucleotide exchange factor 1 isoform X1 [KO:K12330]
107155550  Plekhg5; pleckstrin homology domain-containing family G member 5 isoform X2 [KO:K19464]
107143485  Rhoa; transforming protein RhoA [KO:K04513]
107142324  transforming protein RhoA-like [KO:K04513]
107153326  transforming protein RhoA-like [KO:K04513]
107139600  Rock1; rho-associated protein kinase 1 isoform X1 [KO:K04514] [EC:2.7.11.39]
107137496  Rock2; rho-associated protein kinase 2 isoform X6 [KO:K17388] [EC:2.7.11.39]
107153384  Cxcl12; stromal cell-derived factor 1 isoform X1 [KO:K10031]
107136819  Cxcr4; C-X-C chemokine receptor type 4 [KO:K04189]
107143459  Gnai2; guanine nucleotide-binding protein G(i) subunit alpha-2 isoform X1 [KO:K04630]
107144582  Gnai1; LOW QUALITY PROTEIN: guanine nucleotide-binding protein G(i) subunit alpha-1 [KO:K04630]
107158616  Gnai3; guanine nucleotide-binding protein G(i) subunit alpha-3 [KO:K04630]
107144975  Ptger1; prostaglandin E2 receptor EP1 subtype [KO:K04258]
107138275  Ptger2; prostaglandin E2 receptor EP2 subtype isoform X1 [KO:K04259]
107146416  Ptger3; prostaglandin E2 receptor EP3 subtype isoform X3 [KO:K04260]
107146403  Ptger4; prostaglandin E2 receptor EP4 subtype [KO:K04261]
107137583  guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas isoform X1 [KO:K04632]
107137572  Gnas; neuroendocrine secretory protein 55 [KO:K04632]
107146235  Adcy1; adenylate cyclase type 1 [KO:K08041] [EC:4.6.1.1]
107146314  Adcy2; adenylate cyclase type 2 [KO:K08042] [EC:4.6.1.1]
107137043  Adcy3; adenylate cyclase type 3 isoform X1 [KO:K08043] [EC:4.6.1.1]
107147463  Adcy4; adenylate cyclase type 4 isoform X1 [KO:K08044] [EC:4.6.1.1]
107143106  Adcy5; adenylate cyclase type 5 [KO:K08045] [EC:4.6.1.1]
107148587  Adcy6; adenylate cyclase type 6 isoform X2 [KO:K08046] [EC:4.6.1.1]
107144878  Adcy7; adenylate cyclase type 7 isoform X1 [KO:K08047] [EC:4.6.1.1]
107143016  Adcy8; adenylate cyclase type 8 isoform X1 [KO:K08048] [EC:4.6.1.1]
107146665  Adcy9; adenylate cyclase type 9 [KO:K08049] [EC:4.6.1.1]
107135580  cAMP-dependent protein kinase catalytic subunit beta [KO:K04345] [EC:2.7.11.11]
107158295  Prkacb; cAMP-dependent protein kinase catalytic subunit beta isoform X1 [KO:K04345] [EC:2.7.11.11]
107144974  Prkaca; cAMP-dependent protein kinase catalytic subunit alpha [KO:K04345] [EC:2.7.11.11]
107155582  Gnb1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 [KO:K04536]
107147087  Gnb2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 [KO:K04537]
107154943  Gnb3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 isoform X1 [KO:K07825]
107149461  Gnb4; guanine nucleotide-binding protein subunit beta-4 isoform X1 [KO:K04538]
107137620  Gnb5; guanine nucleotide-binding protein subunit beta-5 [KO:K04539]
107143498  Gng2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 [KO:K07826]
107135927  Gng3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 [KO:K04540]
107157965  Gng4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 [KO:K04541]
107158288  Gng5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 [KO:K04542]
107143532  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5-like [KO:K04542]
107157268  Gng7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 [KO:K04543]
107151728  Gng8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 [KO:K04544]
107141225  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 [KO:K04545]
107144757  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10-like [KO:K04545]
107149406  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10-like [KO:K04545]
107151942  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10-like [KO:K04545]
107145232  Gng14; putative guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-14 [KO:K04347]
107146407  Gng12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 [KO:K04347]
107146761  Gng13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 [KO:K04547]
107134493  guanine nucleotide-binding protein G(T) subunit gamma-T1-like [KO:K04548]
107150476  Gngt2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 [KO:K04549]
107138754  Col4a4; collagen alpha-4(IV) chain isoform X1 [KO:K06237]
107140898  Col4a2; collagen alpha-2(IV) chain isoform X1 [KO:K06237]
107140899  Col4a1; collagen alpha-1(IV) chain isoform X1 [KO:K06237]
107138412  Col4a3; collagen alpha-3(IV) chain isoform X1 [KO:K06237]
107152443  Col4a5; collagen alpha-5(IV) chain [KO:K06237]
107152445  Col4a6; collagen alpha-6(IV) chain [KO:K06237]
107152136  Lama2; laminin subunit alpha-2 isoform X1 [KO:K05637]
107139357  Lama1; laminin subunit alpha-1 [KO:K05637]
107139578  Lama3; laminin subunit alpha-3 isoform X1 [KO:K06240]
107152263  Lama5; laminin subunit alpha-5 [KO:K06240]
107154678  Lama4; laminin subunit alpha-4 isoform X1 [KO:K06241]
107144537  Lamb1; laminin subunit beta-1 [KO:K05636]
107143494  Lamb2; laminin subunit beta-2 [KO:K06243]
107140587  Lamb3; laminin subunit beta-3 [KO:K06244]
107144421  Lamb4; laminin subunit beta-4 isoform X1 [KO:K06245]
107147313  Lamc1; LOW QUALITY PROTEIN: laminin subunit gamma-1 [KO:K05635]
107147312  Lamc2; laminin subunit gamma-2 [KO:K06246]
107151993  Lamc3; LOW QUALITY PROTEIN: laminin subunit gamma-3 [KO:K06247]
107138669  Fn1; fibronectin isoform X3 [KO:K05717]
107151937  Itga2; integrin alpha-2 [KO:K06481]
107150514  Itga2b; integrin alpha-IIb [KO:K06476]
107150463  Itga3; integrin alpha-3 isoform X2 [KO:K06482]
107136925  Itga6; integrin alpha-6 isoform X1 [KO:K06485]
107138529  Itgav; integrin alpha-V isoform X1 [KO:K06487]
107140415  Itgb1; integrin beta-1 isoform X2 [KO:K05719]
107142960  Ptk2; focal adhesion kinase 1 isoform X22 [KO:K05725] [EC:2.7.10.2]
107143149  Pik3cb; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
107149519  Pik3ca; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
107155522  Pik3cd; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
107139438  Pik3r1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X2 [KO:K02649]
107141811  Pik3r3; phosphatidylinositol 3-kinase regulatory subunit gamma [KO:K02649]
107145061  Pik3r2; phosphatidylinositol 3-kinase regulatory subunit beta [KO:K02649]
107153335  Pten; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X1 [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
107153831  Nkx3-1; homeobox protein Nkx-3.1 [KO:K09348]
107151082  Akt1; RAC-alpha serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
107140468  Akt3; RAC-gamma serine/threonine-protein kinase isoform X2 [KO:K04456] [EC:2.7.11.1]
107151462  Akt2; RAC-beta serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
107149793  Chuk; inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1 [KO:K04467] [EC:2.7.11.10]
107159633  Ikbkb; inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1 [KO:K07209] [EC:2.7.11.10]
107160284  Ikbkg; NF-kappa-B essential modulator isoform X3 [KO:K07210]
107143750  Nfkbia; NF-kappa-B inhibitor alpha [KO:K04734]
107141352  Nfkb1; nuclear factor NF-kappa-B p105 subunit isoform X1 [KO:K02580]
107149833  Nfkb2; nuclear factor NF-kappa-B p100 subunit isoform X3 [KO:K04469]
107156942  Rela; transcription factor p65 [KO:K04735]
107147540  Ptgs2; prostaglandin G/H synthase 2 [KO:K11987] [EC:1.14.99.1]
107155278  Nos2; nitric oxide synthase, inducible isoform X2 [KO:K13241] [EC:1.14.13.39]
107139463  Bcl2; apoptosis regulator Bcl-2 isoform X1 [KO:K02161]
107145909  Birc2; baculoviral IAP repeat-containing protein 2 [KO:K16060]
107145910  Birc3; baculoviral IAP repeat-containing protein 3 isoform X1 [KO:K16060]
107152984  E3 ubiquitin-protein ligase XIAP isoform X1 [KO:K04725] [EC:2.3.2.27]
107148893  Birc7; baculoviral IAP repeat-containing protein 7 isoform X1 [KO:K16061]
107143681  bcl-2-like protein 1 [KO:K04570]
107139077  Bcl2l1; bcl-2-like protein 1 isoform X1 [KO:K04570]
107142240  LOW QUALITY PROTEIN: bcl-2-like protein 1 [KO:K04570]
107153030  bcl-2-like protein 1 [KO:K04570]
107152135  Traf1; TNF receptor-associated factor 1 isoform X1 [KO:K03172]
107159171  Traf2; TNF receptor-associated factor 2 isoform X2 [KO:K03173] [EC:2.3.2.27]
107150805  Traf3; TNF receptor-associated factor 3 isoform X1 [KO:K03174]
107155151  Traf4; TNF receptor-associated factor 4 [KO:K09848]
107140575  Traf5; TNF receptor-associated factor 5 isoform X2 [KO:K09849]
107135761  Traf6; TNF receptor-associated factor 6 [KO:K03175] [EC:2.3.2.27]
107155502  Mtor; serine/threonine-protein kinase mTOR [KO:K07203] [EC:2.7.11.1]
107150382  Rps6kb1; ribosomal protein S6 kinase beta-1 isoform X1 [KO:K04688] [EC:2.7.11.1]
107157003  Rps6kb2; ribosomal protein S6 kinase beta-2 isoform X1 [KO:K04688] [EC:2.7.11.1]
107135974  Bad; bcl2-associated agonist of cell death [KO:K02158]
107136379  forkhead box protein O1 [KO:K07201]
107140789  Foxo1; forkhead box protein O1 [KO:K07201]
107139728  Mdm2; E3 ubiquitin-protein ligase Mdm2 [KO:K06643] [EC:2.3.2.27]
107153032  E3 ubiquitin-protein ligase Mdm2-like [KO:K06643] [EC:2.3.2.27]
107158442  LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase Mdm2-like [KO:K06643] [EC:2.3.2.27]
107158007  Tp53; cellular tumor antigen p53 [KO:K04451]
107152676  Cdkn1b; cyclin-dependent kinase inhibitor 1B [KO:K06624]
107143854  Cdkn1a; cyclin-dependent kinase inhibitor 1 [KO:K06625]
107154530  Bcr; breakpoint cluster region protein [KO:K08878] [EC:2.7.11.1]
107151996  Abl1; tyrosine-protein kinase ABL1 isoform X1 [KO:K06619] [EC:2.7.10.2]
107154688  Crkl; crk-like protein isoform X1 [KO:K04438]
107155214  Crk; adapter molecule crk isoform X1 [KO:K04438]
107145778  Cbl; E3 ubiquitin-protein ligase CBL isoform X1 [KO:K04707] [EC:2.3.2.27]
107150571  Stat5a; signal transducer and activator of transcription 5A isoform X1 [KO:K11223]
107150572  signal transducer and activator of transcription 5B isoform X1 [KO:K11224]
107143864  Pim1; serine/threonine-protein kinase pim-1 [KO:K04702] [EC:2.7.11.1]
107134421  Pim2; serine/threonine-protein kinase pim-2 [KO:K08806] [EC:2.7.11.1]
107154354  Kng1; kininogen-1 isoform X3 [KO:K03898]
107149254  Edn1; endothelin-1 [KO:K16366]
107145699  Bdkrb1; B1 bradykinin receptor [KO:K03915]
107150360  Bdkrb2; B2 bradykinin receptor [KO:K03916]
107141249  Ednra; endothelin-1 receptor [KO:K04197]
107153782  Ednrb; endothelin receptor type B [KO:K04198]
107148216  guanine nucleotide-binding protein G(q) subunit alpha [KO:K04634]
107157430  Gna11; guanine nucleotide-binding protein subunit alpha-11 [KO:K04635]
107135966  Plcb3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 isoform X1 [KO:K05858] [EC:3.1.4.11]
107138232  Plcb2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X1 [KO:K05858] [EC:3.1.4.11]
107145524  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X3 [KO:K05858] [EC:3.1.4.11]
107145453  Plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 [KO:K05858] [EC:3.1.4.11]
107158309  Prkca; protein kinase C alpha type [KO:K02677] [EC:2.7.11.13]
107146552  Prkcb; protein kinase C beta type isoform X1 [KO:K19662] [EC:2.7.11.13]
107158898  Prkcg; protein kinase C gamma type [KO:K19663] [EC:2.7.11.13]
107136571  Il2; interleukin-2 [KO:K05429]
107147998  Il3; interleukin-3 [KO:K04736]
107148001  Il4; interleukin-4 [KO:K05430]
107148178  Il5; interleukin-5 [KO:K05428]
107146026  Il6; interleukin-6 [KO:K05405]
107142463  Il7; interleukin-7 isoform X2 [KO:K05431]
107143551  Il12a; interleukin-12 subunit alpha [KO:K05406]
107148164  Il12b; interleukin-12 subunit beta [KO:K05425]
107148000  Il13; interleukin-13 [KO:K05435]
107141230  Il15; interleukin-15 [KO:K05433]
107139832  Il23a; interleukin-23 subunit alpha [KO:K05426]
107146608  Epo; erythropoietin [KO:K05437]
107134700  interferon alpha-5-like [KO:K05414]
107147930  interferon alpha-5-like [KO:K05414]
107135123  interferon alpha-13-like [KO:K05414]
107156481  interferon alpha-5-like [KO:K05414]
107156482  interferon alpha-5-like [KO:K05414]
107156485  interferon alpha-5-like [KO:K05414]
107156486  interferon alpha-5-like [KO:K05414]
107156487  interferon alpha-5-like [KO:K05414]
107156488  interferon alpha-5-like [KO:K05414]
107140076  Ifng; interferon gamma [KO:K04687]
107150214  Il2ra; interleukin-2 receptor subunit alpha [KO:K05068]
107139886  Il2rb; interleukin-2 receptor subunit beta isoform X2 [KO:K05069]
107155679  Il2rg; cytokine receptor common subunit gamma [KO:K05070]
107146879  Il4r; LOW QUALITY PROTEIN: interleukin-4 receptor subunit alpha [KO:K05071]
107139666  cytokine receptor common subunit beta-like [KO:K04738]
107139667  cytokine receptor common subunit beta-like [KO:K04738]
107150173  Il5ra; interleukin-5 receptor subunit alpha [KO:K05067]
107156605  Il6r; interleukin-6 receptor subunit alpha [KO:K05055]
107151880  Il6st; interleukin-6 receptor subunit beta [KO:K05060]
107151121  Il7r; LOW QUALITY PROTEIN: interleukin-7 receptor subunit alpha [KO:K05072]
107145059  Il12rb1; interleukin-12 receptor subunit beta-1 [KO:K05063]
107141672  Il12rb2; interleukin-12 receptor subunit beta-2 isoform X2 [KO:K05064]
107153005  Il13ra1; interleukin-13 receptor subunit alpha-1 [KO:K05076]
107150213  Il15ra; interleukin-15 receptor subunit alpha isoform X1 [KO:K05074]
107141420  Il23r; interleukin-23 receptor isoform X1 [KO:K05065]
107145210  Epor; erythropoietin receptor [KO:K05079]
107136440  Ifnar1; interferon alpha/beta receptor 1 isoform X1 [KO:K05130]
107136438  Ifnar2; interferon alpha/beta receptor 2 isoform X1 [KO:K05131]
107155664  Ifngr1; interferon gamma receptor 1 isoform X1 [KO:K05132]
107136144  Ifngr2; interferon gamma receptor 2 [KO:K05133]
107137329  Eml4; echinoderm microtubule-associated protein-like 4 isoform X2 [KO:K15420]
107137383  Alk; ALK tyrosine kinase receptor [KO:K05119] [EC:2.7.10.1]
107138242  Rasgrp1; RAS guanyl-releasing protein 1 isoform X1 [KO:K04350]
107135982  Rasgrp2; RAS guanyl-releasing protein 2 isoform X1 [KO:K12361]
107137363  Rasgrp3; ras guanyl-releasing protein 3 isoform X1 [KO:K12362]
107151494  Rasgrp4; RAS guanyl-releasing protein 4 [KO:K12363]
107141689  Jak1; tyrosine-protein kinase JAK1 isoform X1 [KO:K11217] [EC:2.7.10.2]
107148240  Jak2; tyrosine-protein kinase JAK2 isoform X1 [KO:K04447] [EC:2.7.10.2]
107145057  Jak3; tyrosine-protein kinase JAK3 isoform X1 [KO:K11218] [EC:2.7.10.2]
107150570  Stat3; signal transducer and activator of transcription 3 isoform X1 [KO:K04692]
107138551  Stat1; signal transducer and activator of transcription 1-alpha/beta isoform X1 [KO:K11220]
107140168  Stat2; signal transducer and activator of transcription 2 isoform X1 [KO:K11221]
107138552  Stat4; signal transducer and activator of transcription 4 [KO:K11222]
107140146  Stat6; signal transducer and activator of transcription 6 isoform X1 [KO:K11225]
107143955  Vegfa; vascular endothelial growth factor A isoform X1 [KO:K05448]
107135964  Vegfb; vascular endothelial growth factor B isoform X2 [KO:K16858]
107149280  Pgf; placenta growth factor isoform X1 [KO:K16859]
107142701  Vegfc; vascular endothelial growth factor C [KO:K05449]
107144245  Vegfd; vascular endothelial growth factor D [KO:K05449]
107137192  Tgfa; protransforming growth factor alpha isoform X1 [KO:K08774]
107141390  Egf; LOW QUALITY PROTEIN: pro-epidermal growth factor [KO:K04357]
107146095  Egfr; epidermal growth factor receptor isoform X1 [KO:K04361] [EC:2.7.10.1]
107160020  Erbb2; receptor tyrosine-protein kinase erbB-2 [KO:K05083] [EC:2.7.10.1]
107155905  Pdgfa; platelet-derived growth factor subunit A [KO:K04359]
107139238  Pdgfra; platelet-derived growth factor receptor alpha [KO:K04363] [EC:2.7.10.1]
107154281  Pdgfrb; platelet-derived growth factor receptor beta [KO:K05089] [EC:2.7.10.1]
107139962  Igf1; insulin-like growth factor I isoform X1 [KO:K05459]
107157065  Igf2; insulin-like growth factor II isoform X1 [KO:K13769]
107148359  Igf1r; insulin-like growth factor 1 receptor [KO:K05087] [EC:2.7.10.1]
107139702  Kitlg; kit ligand isoform X1 [KO:K05461]
107139239  Kit; mast/stem cell growth factor receptor Kit isoform X8 [KO:K05091] [EC:2.7.10.1]
107151249  Flt3lg; fms-related tyrosine kinase 3 ligand isoform X3 [KO:K05454]
107140769  Flt3; receptor-type tyrosine-protein kinase FLT3 [KO:K05092] [EC:2.7.10.1]
107144587  Hgf; hepatocyte growth factor isoform X1 [KO:K05460]
107144489  Met; hepatocyte growth factor receptor isoform X1 [KO:K05099] [EC:2.7.10.1]
107142266  Fgf1; fibroblast growth factor 1 isoform X2 [KO:K18496]
107142609  Fgf20; fibroblast growth factor 20 [KO:K04358]
107149993  Fgf8; fibroblast growth factor 8 [KO:K04358]
107138118  Fgf7; fibroblast growth factor 7 [KO:K04358]
107147961  Fgf18; fibroblast growth factor 18 [KO:K04358]
107159277  Fgf16; fibroblast growth factor 16 [KO:K04358]
107151908  Fgf10; fibroblast growth factor 10 [KO:K04358]
107153651  Fgf5; fibroblast growth factor 5 isoform X1 [KO:K04358]
107142234  fibroblast growth factor 4-like [KO:K04358]
107153940  Fgf17; fibroblast growth factor 17 isoform X1 [KO:K04358]
107154986  Fgf6; fibroblast growth factor 6 [KO:K04358]
107156889  Fgf3; fibroblast growth factor 3 [KO:K04358]
107156928  Fgf4; fibroblast growth factor 4 [KO:K04358]
107157551  Fgf22; fibroblast growth factor 22 isoform X1 [KO:K04358]
107156888  Fgf19; fibroblast growth factor 19 [KO:K22603]
107151276  Fgf21; fibroblast growth factor 21 [KO:K22429]
107161066  fibroblast growth factor 23-like [KO:K22428]
107154988  Fgf23; fibroblast growth factor 23 [KO:K22428]
107155394  Fgfr1; fibroblast growth factor receptor 1 isoform X2 [KO:K04362] [EC:2.7.10.1]
107152829  Fgfr2; fibroblast growth factor receptor 2 isoform X1 [KO:K05093] [EC:2.7.10.1]
107139080  Fgfr3; fibroblast growth factor receptor 3 isoform X2 [KO:K05094] [EC:2.7.10.1]
107144715  Fgfr4; fibroblast growth factor receptor 4 [KO:K05095] [EC:2.7.10.1]
107157785  Grb2; growth factor receptor-bound protein 2 [KO:K04364]
107137015  Sos1; son of sevenless homolog 1 [KO:K03099]
107143517  Sos2; son of sevenless homolog 2 [KO:K03099]
107157108  Hras; GTPase HRas isoform X1 [KO:K02833]
107152729  Kras; GTPase KRas isoform X1 [KO:K07827]
107156178  Nras; GTPase NRas [KO:K07828]
107144326  Araf; serine/threonine-protein kinase A-Raf isoform X1 [KO:K08845] [EC:2.7.11.1]
107149118  Braf; serine/threonine-protein kinase B-raf isoform X7 [KO:K04365] [EC:2.7.11.1]
107150090  Raf1; RAF proto-oncogene serine/threonine-protein kinase isoform X2 [KO:K04366] [EC:2.7.11.1]
107138000  Map2k1; dual specificity mitogen-activated protein kinase kinase 1 isoform X1 [KO:K04368] [EC:2.7.12.2]
107157283  Map2k2; dual specificity mitogen-activated protein kinase kinase 2 [KO:K04369] [EC:2.7.12.2]
107146562  Mapk3; mitogen-activated protein kinase 3 [KO:K04371] [EC:2.7.11.24]
107154676  Mapk1; mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
107141712  Jun; transcription factor Jun [KO:K04448]
107149351  Fos; protein c-Fos [KO:K04379]
107153508  Ets1; protein C-ets-1 isoform X4 [KO:K02678]
107145904  Mmp1; interstitial collagenase [KO:K01388] [EC:3.4.24.7]
107144864  Mmp2; 72 kDa type IV collagenase [KO:K01398] [EC:3.4.24.24]
107136735  Mmp9; matrix metalloproteinase-9 [KO:K01403] [EC:3.4.24.35]
107158812  Cxcl8; interleukin-8 [KO:K10030]
125611315  C-X-C motif chemokine 15-like [KO:K10030]
107140113  Cdk4; cyclin-dependent kinase 4 [KO:K02089] [EC:2.7.11.22]
107149869  Rps6ka5; ribosomal protein S6 kinase alpha-5 isoform X1 [KO:K04445] [EC:2.7.11.1]
107153442  Ret; proto-oncogene tyrosine-protein kinase receptor Ret isoform X1 [KO:K05126] [EC:2.7.10.1]
107158203  Ccdc6; coiled-coil domain-containing protein 6 [KO:K09288]
107153357  Ncoa4; nuclear receptor coactivator 4 isoform X1 [KO:K09289]
107156672  Ntrk1; high affinity nerve growth factor receptor [KO:K03176] [EC:2.7.10.1]
107141701  LOW QUALITY PROTEIN: tropomyosin alpha-3 chain-like [KO:K09290]
107141896  LOW QUALITY PROTEIN: tropomyosin alpha-3 chain-like [KO:K09290]
107156756  Tpm3; tropomyosin alpha-3 chain isoform X5 [KO:K09290]
107147297  Tpr; nucleoprotein TPR isoform X1 [KO:K09291]
107136358  Tfg; protein TFG isoform X1 [KO:K09292]
107143448  Rassf1; ras association domain-containing protein 1 isoform X2 [KO:K09850]
107140609  Rassf5; ras association domain-containing protein 5 isoform X1 [KO:K08015]
107136512  Stk4; serine/threonine-protein kinase 4 isoform X1 [KO:K04411]
107138032  Dapk2; death-associated protein kinase 2 isoform X1 [KO:K08803] [EC:2.7.11.1]
107157443  Dapk3; death-associated protein kinase 3 [KO:K08803] [EC:2.7.11.1]
107154852  LOW QUALITY PROTEIN: death-associated protein kinase 1 [KO:K08803] [EC:2.7.11.1]
107138082  Plcg1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [KO:K01116] [EC:3.1.4.11]
107150868  Plcg2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 isoform X2 [KO:K05859] [EC:3.1.4.11]
107144330  Elk1; ETS domain-containing protein Elk-1 [KO:K04375]
107137302  Calm2; calmodulin-2 isoform X1 [KO:K02183]
107149860  Calm1; calmodulin-1 [KO:K02183]
107150315  calmodulin-like [KO:K02183]
107150317  calmodulin-like protein 3 [KO:K02183]
107151326  Calm3; calmodulin-3 [KO:K02183]
107137985  Calml4; LOW QUALITY PROTEIN: calmodulin-like protein 4 [KO:K02183]
107153315  calmodulin-like [KO:K02183]
107155450  Calml6; calmodulin-like protein 6 [KO:K02183]
107141405  Camk2d; calcium/calmodulin-dependent protein kinase type II subunit delta isoform X9 [KO:K04515] [EC:2.7.11.17]
107142680  Camk2a; calcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1 [KO:K04515] [EC:2.7.11.17]
107146068  Camk2b; calcium/calmodulin-dependent protein kinase type II subunit beta isoform X1 [KO:K04515] [EC:2.7.11.17]
107158156  Camk2g; calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X1 [KO:K04515] [EC:2.7.11.17]
107151971  Ralgds; ral guanine nucleotide dissociation stimulator isoform X6 [KO:K08732]
107146193  Rala; ras-related protein Ral-A isoform X2 [KO:K07834]
107155719  Ralb; ras-related protein Ral-B [KO:K07835]
107159444  Ralbp1; ralA-binding protein 1 [KO:K08773]
107142153  Cdc42; cell division control protein 42 homolog isoform X2 [KO:K04393]
107155970  Rac1; ras-related C3 botulinum toxin substrate 1 isoform X2 [KO:K04392]
107157825  Rac3; ras-related C3 botulinum toxin substrate 3 [KO:K07861]
107149483  Pld1; phospholipase D1 isoform X1 [KO:K01115] [EC:3.1.4.4]
107159403  Pld2; phospholipase D2 isoform X1 [KO:K01115] [EC:3.1.4.4]
107159793  Mapk9; mitogen-activated protein kinase 9 isoform X1 [KO:K04440] [EC:2.7.11.24]
107153372  Mapk8; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
107153644  Mapk10; mitogen-activated protein kinase 10 isoform X1 [KO:K04440] [EC:2.7.11.24]
107144171  LOW QUALITY PROTEIN: mitogen-activated protein kinase 8-like [KO:K04440] [EC:2.7.11.24]
107154039  Pax8; paired box protein Pax-8 isoform X1 [KO:K09293]
107150087  Pparg; peroxisome proliferator-activated receptor gamma isoform X2 [KO:K08530]
107159163  Rxra; retinoic acid receptor RXR-alpha isoform X1 [KO:K08524]
107143792  Rxrb; LOW QUALITY PROTEIN: retinoic acid receptor RXR-beta [KO:K08525]
107147439  Rxrg; retinoic acid receptor RXR-gamma isoform X3 [KO:K08526]
107145546  Rarb; retinoic acid receptor beta isoform X2 [KO:K08528]
107156275  Esr1; estrogen receptor isoform X1 [KO:K08550]
107145990  Esr2; estrogen receptor beta isoform X1 [KO:K08551]
107137457  Ncoa1; nuclear receptor coactivator 1 isoform X4 [KO:K09101] [EC:2.3.1.48]
107136340  Ncoa3; nuclear receptor coactivator 3 isoform X2 [KO:K11256] [EC:2.3.1.48]
107148811  Sp1; transcription factor Sp1 isoform X1 [KO:K04684]
107143827  Ppard; peroxisome proliferator-activated receptor delta isoform X1 [KO:K04504]
107150587  junction plakoglobin [KO:K10056]
107145845  Zbtb16; zinc finger and BTB domain-containing protein 16 isoform X1 [KO:K10055]
107150624  Rara; retinoic acid receptor alpha isoform X1 [KO:K08527]
107136738  Ccna2; cyclin-A2 isoform X1 [KO:K06627]
107140851  Ccna1; cyclin-A1 [KO:K06627]
107137956  Pml; protein PML isoform X1 [KO:K10054] [EC:2.3.2.-]
107136457  Runx1; runt-related transcription factor 1 isoform X2 [KO:K08367]
107142496  Runx1t1; LOW QUALITY PROTEIN: protein CBFA2T1 [KO:K10053]
107135812  Spi1; transcription factor PU.1 isoform X1 [KO:K09438]
107160206  granulocyte-macrophage colony-stimulating factor receptor subunit alpha [KO:K05066]
107160207  granulocyte-macrophage colony-stimulating factor receptor subunit alpha-like isoform X1 [KO:K05066]
107141944  Csf3r; granulocyte colony-stimulating factor receptor isoform X1 [KO:K05061]
107142656  Csf1r; macrophage colony-stimulating factor 1 receptor isoform X1 [KO:K05090] [EC:2.7.10.1]
107147876  cyclin-dependent kinase 4 inhibitor B-like [KO:K06621]
107140105  E2f1; transcription factor E2F1 [KO:K17454]
107141554  E2f2; transcription factor E2F2 isoform X1 [KO:K09389]
107149286  E2f3; transcription factor E2F3 [KO:K06620]
107143410  Max; protein max isoform X1 [KO:K04453]
107142205  Zbtb17; zinc finger and BTB domain-containing protein 17 isoform X1 [KO:K10500]
107147875  cyclin-dependent kinase inhibitor 2A-like [KO:K04685]
107160066  Cdk6; cyclin-dependent kinase 6 [KO:K02091] [EC:2.7.11.22]
107154990  Ccnd2; G1/S-specific cyclin-D2 [KO:K10151]
107143908  Ccnd3; G1/S-specific cyclin-D3 isoform X2 [KO:K10152]
107137090  cyclin-dependent kinases regulatory subunit 2 [KO:K02219]
125612843  LOW QUALITY PROTEIN: cyclin-dependent kinases regulatory subunit 2-like [KO:K02219]
107156738  Cks1b; cyclin-dependent kinases regulatory subunit 1 [KO:K02219]
107157611  Cks2; cyclin-dependent kinases regulatory subunit 2 [KO:K02219]
107138192  S-phase kinase-associated protein 1-like isoform X2 [KO:K03094]
107148129  Skp1; S-phase kinase-associated protein 1 isoform X2 [KO:K03094]
107148972  Cul1; cullin-1 [KO:K03347]
107155854  Rbx1; E3 ubiquitin-protein ligase RBX1 isoform X1 [KO:K03868] [EC:2.3.2.32]
107151118  Skp2; S-phase kinase-associated protein 2 isoform X2 [KO:K03875]
107140193  Cdk2; cyclin-dependent kinase 2 isoform X1 [KO:K02206] [EC:2.7.11.22]
107151531  Ccne1; G1/S-specific cyclin-E1 isoform X2 [KO:K06626]
107142513  Ccne2; G1/S-specific cyclin-E2 isoform X1 [KO:K06626]
107141039  Rb1; retinoblastoma-associated protein isoform X2 [KO:K06618]
107146405  Gadd45a; growth arrest and DNA damage-inducible protein GADD45 alpha [KO:K04402]
107157267  Gadd45b; growth arrest and DNA damage-inducible protein GADD45 beta [KO:K04402]
107157608  Gadd45g; growth arrest and DNA damage-inducible protein GADD45 gamma [KO:K04402]
107151268  Bax; apoptosis regulator BAX isoform X1 [KO:K02159]
107143808  Bak1; bcl-2 homologous antagonist/killer [KO:K14021]
107135807  Ddb2; DNA damage-binding protein 2 isoform X1 [KO:K10140]
107152268  Polk; DNA polymerase kappa isoform X1 [KO:K03511] [EC:2.7.7.7]
107146303  Tert; telomerase reverse transcriptase [KO:K11126] [EC:2.7.7.49]
107150120  Mitf; microphthalmia-associated transcription factor isoform X3 [KO:K09455]
107151630  Tgfb1; transforming growth factor beta-1 proprotein [KO:K13375]
107140543  Tgfb2; transforming growth factor beta-2 proprotein isoform X2 [KO:K13376]
107149439  Tgfb3; transforming growth factor beta-3 proprotein [KO:K13377]
107147762  Tgfbr1; TGF-beta receptor type-1 isoform X2 [KO:K04674] [EC:2.7.11.30]
107145534  Tgfbr2; TGF-beta receptor type-2 isoform X1 [KO:K04388] [EC:2.7.11.30]
107139517  Smad2; mothers against decapentaplegic homolog 2 isoform X1 [KO:K04500]
107137992  Smad3; mothers against decapentaplegic homolog 3 isoform X2 [KO:K23605]
107139501  Smad4; mothers against decapentaplegic homolog 4 isoform X1 [KO:K04501]
107149498  Mecom; histone-lysine N-methyltransferase MECOM isoform X15 [KO:K04462] [EC:2.1.1.367]
107139072  Ctbp1; C-terminal-binding protein 1 isoform X1 [KO:K04496] [EC:1.1.1.428]
107147213  C-terminal-binding protein 2-like [KO:K04496] [EC:1.1.1.428]
107152857  Ctbp2; C-terminal-binding protein 2 isoform X1 [KO:K04496] [EC:1.1.1.428]
107142001  Hdac1; histone deacetylase 1 [KO:K06067] [EC:3.5.1.98]
107154686  Hdac2; histone deacetylase 2 [KO:K06067] [EC:3.5.1.98]
107145509  Mlh1; DNA mismatch repair protein Mlh1 isoform X1 [KO:K08734]
107137005  Msh2; DNA mismatch repair protein Msh2 [KO:K08735]
107152325  Msh3; DNA mismatch repair protein Msh3 isoform X1 [KO:K08736]
107137298  Msh6; DNA mismatch repair protein Msh6 isoform X1 [KO:K08737]
107140779  Brca2; breast cancer type 2 susceptibility protein isoform X1 [KO:K08775]
107138223  Rad51; DNA repair protein RAD51 homolog 1 [KO:K04482]
107147374  Faslg; tumor necrosis factor ligand superfamily member 6 [KO:K04389]
107153328  Fas; tumor necrosis factor receptor superfamily member 6 [KO:K04390]
107157044  Fadd; FAS-associated death domain protein [KO:K02373]
107138607  Casp8; caspase-8 isoform X1 [KO:K04398] [EC:3.4.22.61]
107155037  Bid; BH3-interacting domain death agonist isoform X1 [KO:K04726]
125617707  Pmaip1; phorbol-12-myristate-13-acetate-induced protein 1 [KO:K10131]
107154151  Bcl2l11; bcl-2-like protein 11 isoform X1 [KO:K16341]
107146118  cytochrome c, somatic [KO:K08738]
125618140  LOW QUALITY PROTEIN: cytochrome c, testis-specific-like [KO:K08738]
107161017  cytochrome c, somatic [KO:K08738]
107149067  cytochrome c, somatic-like [KO:K08738]
107135575  cytochrome c, somatic-like [KO:K08738]
107151095  cytochrome c, somatic-like [KO:K08738]
107136200  cytochrome c, somatic-like [KO:K08738]
107139684  Apaf1; LOW QUALITY PROTEIN: apoptotic protease-activating factor 1 [KO:K02084]
107149904  Casp7; caspase-7 isoform X3 [KO:K04397] [EC:3.4.22.60]
107145182  Keap1; kelch-like ECH-associated protein 1 isoform X1 [KO:K10456]
107136946  Nfe2l2; nuclear factor erythroid 2-related factor 2 isoform X2 [KO:K05638]
107139907  Hmox1; heme oxygenase 1 [KO:K00510] [EC:1.14.14.18]
107148343  LOW QUALITY PROTEIN: heme oxygenase 1-like [KO:K00510] [EC:1.14.14.18]
107159569  heme oxygenase 1-like [KO:K00510] [EC:1.14.14.18]
107151923  LOW QUALITY PROTEIN: heme oxygenase 1-like [KO:K00510] [EC:1.14.14.18]
107150944  Nqo1; NAD(P)H dehydrogenase [quinone] 1 [KO:K00355] [EC:1.6.5.2]
107136669  Mgst2; microsomal glutathione S-transferase 2 isoform X1 [KO:K00799] [EC:2.5.1.18]
107149868  Gsto1; glutathione S-transferase omega-1 isoform X1 [KO:K00799] [EC:2.5.1.18]
107149870  Gsto2; glutathione S-transferase omega-2 [KO:K00799] [EC:2.5.1.18]
107143994  glutathione S-transferase A3-like isoform X1 [KO:K00799] [EC:2.5.1.18]
107143996  glutathione S-transferase alpha-3 [KO:K00799] [EC:2.5.1.18]
107143997  glutathione S-transferase alpha-3-like [KO:K00799] [EC:2.5.1.18]
107143998  glutathione S-transferase alpha-3-like isoform X3 [KO:K00799] [EC:2.5.1.18]
107144001  glutathione S-transferase alpha-3-like [KO:K00799] [EC:2.5.1.18]
107144002  glutathione S-transferase A1 [KO:K00799] [EC:2.5.1.18]
107144003  glutathione S-transferase A4 [KO:K00799] [EC:2.5.1.18]
107144096  glutathione S-transferase-like isoform X1 [KO:K00799] [EC:2.5.1.18]
107147437  Mgst3; microsomal glutathione S-transferase 3 [KO:K00799] [EC:2.5.1.18]
107158574  Gstm3; glutathione S-transferase Mu 3 isoform X3 [KO:K00799] [EC:2.5.1.18]
107158576  glutathione S-transferase Mu 1 isoform X1 [KO:K00799] [EC:2.5.1.18]
107158579  glutathione S-transferase Mu 2 [KO:K00799] [EC:2.5.1.18]
107158580  Gstm4; glutathione S-transferase Mu 4 isoform X2 [KO:K00799] [EC:2.5.1.18]
107152703  Mgst1; microsomal glutathione S-transferase 1 [KO:K00799] [EC:2.5.1.18]
107154533  glutathione S-transferase theta-4 [KO:K00799] [EC:2.5.1.18]
107154664  glutathione S-transferase theta-3 [KO:K00799] [EC:2.5.1.18]
107154665  glutathione S-transferase theta-1 isoform X1 [KO:K00799] [EC:2.5.1.18]
107154666  glutathione S-transferase theta-2B-like isoform X1 [KO:K00799] [EC:2.5.1.18]
107157012  Gstp1; glutathione S-transferase P isoform X1 [KO:K23790] [EC:2.5.1.18]
107139944  Txnrd1; thioredoxin reductase 1, cytoplasmic isoform X2 [KO:K22182] [EC:1.8.1.9]
107160100  Txnrd3; thioredoxin reductase 3 [KO:K22182] [EC:1.8.1.9]
107154726  Txnrd2; thioredoxin reductase 2, mitochondrial isoform X5 [KO:K22182] [EC:1.8.1.9]
107150134  Vhl; von Hippel-Lindau disease tumor suppressor [KO:K03871]
107142450  Eloc; elongin-C [KO:K03872]
107137283  elongin-C [KO:K03872]
107159622  elongin-C [KO:K03872]
107152958  elongin-C-like [KO:K03872]
107140410  Cul2; cullin-2 isoform X1 [KO:K03870]
107151442  Egln2; prolyl hydroxylase EGLN2 isoform X1 [KO:K09592] [EC:1.14.11.29]
107147239  Egln3; prolyl hydroxylase EGLN3 [KO:K09592] [EC:1.14.11.29]
107140458  Fh; fumarate hydratase, mitochondrial [KO:K01679] [EC:4.2.1.2]
107145894  Hif1a; hypoxia-inducible factor 1-alpha isoform X1 [KO:K08268]
107137310  Epas1; endothelial PAS domain-containing protein 1 isoform X2 [KO:K09095]
107156832  Arnt; aryl hydrocarbon receptor nuclear translocator isoform X1 [KO:K09097]
107148324  Arnt2; aryl hydrocarbon receptor nuclear translocator 2 isoform X7 [KO:K15589]
107146666  CREB-binding protein isoform X1 [KO:K04498] [EC:2.3.1.48]
107155853  Ep300; histone acetyltransferase p300 isoform X1 [KO:K04498] [EC:2.3.1.48]
107141876  Slc2a1; solute carrier family 2, facilitated glucose transporter member 1 [KO:K07299]
107140005  Jag1; protein jagged-1 isoform X1 [KO:K06052]
107144970  Jag2; protein jagged-2 [KO:K21635]
107138211  Dll4; delta-like protein 4 [KO:K06051]
107153087  delta-like protein 1 isoform X1 [KO:K06051]
107153149  delta-like protein 1 [KO:K06051]
107151739  Dll3; delta-like protein 3 [KO:K06051]
107159127  Notch1; neurogenic locus notch homolog protein 1 [KO:K02599]
107158599  Notch2; neurogenic locus notch homolog protein 2 [KO:K20994]
107145027  Notch3; neurogenic locus notch homolog protein 3 [KO:K20995]
107143763  Notch4; neurogenic locus notch homolog protein 4 isoform X1 [KO:K20996]
107154386  Hes1; transcription factor HES-1 [KO:K06054]
107142464  Hey1; hairy/enhancer-of-split related with YRPW motif protein 1 isoform X1 [KO:K09091]
107141493  Heyl; hairy/enhancer-of-split related with YRPW motif-like protein [KO:K09091]
107155148  Hey2; hairy/enhancer-of-split related with YRPW motif protein 2 [KO:K09091]
107159792  Flt4; vascular endothelial growth factor receptor 3 [KO:K05097] [EC:2.7.10.1]
107156278  Shh; sonic hedgehog protein [KO:K11988]
107157623  Ptch1; protein patched homolog 1 [KO:K06225]
107149063  Smo; LOW QUALITY PROTEIN: smoothened homolog [KO:K06226]
107148432  Kif7; kinesin-like protein KIF7 isoform X1 [KO:K18806]
107149839  Sufu; suppressor of fused homolog isoform X1 [KO:K06229]
107140134  Gli1; zinc finger protein GLI1 [KO:K16797]
107136590  Gli2; zinc finger protein GLI2 [KO:K16798]
107146060  Gli3; transcriptional activator GLI3 isoform X1 [KO:K06230]
107145218  Bmp2; LOW QUALITY PROTEIN: bone morphogenetic protein 2 [KO:K21283]
107138284  Bmp4; bone morphogenetic protein 4 isoform X1 [KO:K04662]
107141239  hedgehog-interacting protein isoform X1 [KO:K06231]
107141833  Ptch2; protein patched homolog 2 isoform X1 [KO:K11101]
107155629  Ar; androgen receptor [KO:K08557]
107143959  Hsp90ab1; heat shock protein HSP 90-beta [KO:K04079]
107150665  Hsp90aa1; heat shock protein HSP 90-alpha isoform X1 [KO:K04079]
107139953  Hsp90b1; endoplasmin [KO:K09487]
Compound
C00027  Hydrogen peroxide
C00039  DNA
C00076  Calcium cation
C00122  Fumarate
C00149  (S)-Malate
C00165  Diacylglycerol
C00187  Cholesterol
C00280  Androstenedione
C00410  Progesterone
C00416  Phosphatidate
C00533  Nitric oxide
C00535  Testosterone
C00575  3',5'-Cyclic AMP
C00584  Prostaglandin E2
C00681  1-Acyl-sn-glycerol 3-phosphate
C00704  Superoxide
C00735  Cortisol
C00762  Cortisone
C00777  Retinoate
C00951  Estradiol-17beta
C01227  Dehydroepiandrosterone
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01471  Acrolein
C03917  Dihydrotestosterone
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C07653  Flutamide
C15493  9-cis-Retinoic acid
C16038  2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
C16844  Hydroxyl radical
C21641  Hydroperoxyl radical
C21642  4-Hydroxynonenal
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Related
pathway
mmma03320  PPAR signaling pathway
mmma04010  MAPK signaling pathway
mmma04020  Calcium signaling pathway
mmma04024  cAMP signaling pathway
mmma04060  Cytokine-cytokine receptor interaction
mmma04066  HIF-1 signaling pathway
mmma04110  Cell cycle
mmma04115  p53 signaling pathway
mmma04150  mTOR signaling pathway
mmma04151  PI3K-Akt signaling pathway
mmma04210  Apoptosis
mmma04310  Wnt signaling pathway
mmma04330  Notch signaling pathway
mmma04340  Hedgehog signaling pathway
mmma04350  TGF-beta signaling pathway
mmma04370  VEGF signaling pathway
mmma04510  Focal adhesion
mmma04512  ECM-receptor interaction
mmma04520  Adherens junction
mmma04630  JAK-STAT signaling pathway
mmma04915  Estrogen signaling pathway
KO pathway
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