Entry Name Pathways in cancer - Macaca mulatta (rhesus monkey)
Class Human Diseases; Cancer: overviewBRITE hierarchy
Pathway map Organism Macaca mulatta (rhesus monkey) [GN:
mcc ]
Gene 100169972 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 [KO:K04540 ]
100423838 DVL3; segment polarity protein dishevelled homolog DVL-3 isoform X1 [KO:K02353 ]
100424606 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 [KO:K04347 ]
100429106 GNA12; guanine nucleotide-binding protein subunit alpha-12 isoform X1 [KO:K04346 ]
106992315 TGFB1; transforming growth factor beta-1 proprotein isoform X2 [KO:K13375 ]
106995138 IL3RA; interleukin-3 receptor subunit alpha isoform X1 [KO:K04737 ]
106996285 VHL; von Hippel-Lindau disease tumor suppressor isoform X1 [KO:K03871 ]
114669860 NFKB2; LOW QUALITY PROTEIN: nuclear factor NF-kappa-B p100 subunit [KO:K04469 ]
114673968 GNG14; putative guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-14 [KO:K04347 ]
114673987 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 isoform X1 [KO:K04544 ]
574127 IL6ST; interleukin-6 receptor subunit beta precursor [KO:K05060 ]
574128 STAT3; signal transducer and activator of transcription 3 isoform X1 [KO:K04692 ]
574129 STAT5A; signal transducer and activator of transcription 5A isoform 2 [KO:K11223 ]
574159 FASLG; tumor necrosis factor ligand superfamily member 6 [KO:K04389 ]
574190 PPARG; peroxisome proliferator-activated receptor gamma [KO:K08530 ]
574199 IL12RB1; interleukin-12 receptor subunit beta-1 [KO:K05063 ]
574209 VEGFA; vascular endothelial growth factor A isoform 1 precursor [KO:K05448 ]
574300 IL2RA; interleukin-2 receptor subunit alpha precursor [KO:K05068 ]
574332 FAS; tumor necrosis factor receptor superfamily member 6 precursor [KO:K04390 ]
574334 CXCL12; stromal cell-derived factor 1 precursor [KO:K10031 ]
574345 FGF7; fibroblast growth factor 7 precursor [KO:K04358 ]
613031 TGFA; protransforming growth factor alpha isoform X2 [KO:K08774 ]
613251 PTGER1; prostaglandin E2 receptor EP1 subtype [KO:K04258 ]
641338 IL2RG; cytokine receptor common subunit gamma precursor [KO:K05070 ]
693443 APC; adenomatous polyposis coli protein isoform X1 [KO:K02085 ]
693650 STAT1; signal transducer and activator of transcription 1-alpha/beta [KO:K11220 ]
693753 CALML4; LOW QUALITY PROTEIN: calmodulin-like protein 4 [KO:K02183 ]
693854 STAT4; signal transducer and activator of transcription 4 isoform X2 [KO:K11222 ]
693961 TRAF3; TNF receptor-associated factor 3 isoform X1 [KO:K03174 ]
694164 APAF1; apoptotic protease-activating factor 1 [KO:K02084 ]
694560 TCF7L1; transcription factor 7-like 1 isoform X2 [KO:K04490 ]
694618 BMP4; bone morphogenetic protein 4 isoform X1 [KO:K04662 ]
694747 IL12B; interleukin-12 subunit beta precursor [KO:K05425 ]
694929 HES5; transcription factor HES-5 isoform X1 [KO:K06055 ]
695064 ZBTB16; zinc finger and BTB domain-containing protein 16 [KO:K10055 ]
695220 PTGER4; prostaglandin E2 receptor EP4 subtype [KO:K04261 ]
695382 RASSF5; ras association domain-containing protein 5 isoform X1 [KO:K08015 ]
695441 GNB5; guanine nucleotide-binding protein subunit beta-5 isoform X1 [KO:K04539 ]
695537 MITF; microphthalmia-associated transcription factor [KO:K09455 ]
695776 LEF1; lymphoid enhancer-binding factor 1 isoform X3 [KO:K04492 ]
695843 LRP6; low-density lipoprotein receptor-related protein 6 precursor [KO:K03068 ]
695896 FGF5; fibroblast growth factor 5 isoform X1 [KO:K04358 ]
696327 ZBTB17; zinc finger and BTB domain-containing protein 17 [KO:K10500 ]
696331 IL2RB; interleukin-2 receptor subunit beta precursor [KO:K05069 ]
696685 LAMA4; laminin subunit alpha-4 isoform X1 [KO:K06241 ]
696709 RAC2; ras-related C3 botulinum toxin substrate 2 [KO:K07860 ]
696749 RUNX1; runt-related transcription factor 1 [KO:K08367 ]
697069 PLCG1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1 [KO:K01116 ] [EC:3.1.4.11 ]
697082 BCL2L11; bcl-2-like protein 11 isoform X1 [KO:K16341 ]
697188 CDKN1B; cyclin-dependent kinase inhibitor 1B [KO:K06624 ]
697324 CKS2; cyclin-dependent kinases regulatory subunit 2 [KO:K02219 ]
697329 EDNRB; endothelin receptor type B isoform X2 [KO:K04198 ]
697453 DLL3; LOW QUALITY PROTEIN: delta-like protein 3 [KO:K06051 ]
697508 CSF2RB; cytokine receptor common subunit beta isoform X1 [KO:K04738 ]
697581 SMAD2; mothers against decapentaplegic homolog 2 [KO:K04500 ]
697671 BIRC7; baculoviral IAP repeat-containing protein 7 isoform X1 [KO:K16061 ]
697835 GADD45G; growth arrest and DNA damage-inducible protein GADD45 gamma [KO:K04402 ]
698444 IGF1; insulin-like growth factor I precursor [KO:K05459 ]
698619 EGF; pro-epidermal growth factor isoform X2 [KO:K04357 ]
698782 MLH1; DNA mismatch repair protein Mlh1 isoform X1 [KO:K08734 ]
698840 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 [KO:K04549 ]
698922 ELOC; transcription elongation factor B polypeptide 1 [KO:K03872 ]
698931 SLC2A1; solute carrier family 2, facilitated glucose transporter member 1 [KO:K07299 ]
698996 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha [KO:K02649 ]
699310 GNAI3; guanine nucleotide-binding protein G(k) subunit alpha [KO:K04630 ]
699385 HEY1; hairy/enhancer-of-split related with YRPW motif protein 1 isoform X1 [KO:K09091 ]
699502 VEGFC; vascular endothelial growth factor C precursor [KO:K05449 ]
699604 IFNAR1; interferon alpha/beta receptor 1 precursor [KO:K05130 ]
699726 IFNAR2; interferon alpha/beta receptor 2 isoform X1 [KO:K05131 ]
699869 IL7R; interleukin-7 receptor subunit alpha [KO:K05072 ]
699889 CCDC6; coiled-coil domain-containing protein 6 [KO:K09288 ]
700206 RARA; retinoic acid receptor alpha isoform X2 [KO:K08527 ]
700382 CCNE2; G1/S-specific cyclin-E2 isoform X2 [KO:K06626 ]
700485 RARB; retinoic acid receptor beta isoform X2 [KO:K08528 ]
700589 CCNE1; G1/S-specific cyclin-E1 isoform X1 [KO:K06626 ]
700606 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 [KO:K04546 ]
700617 SKP2; S-phase kinase-associated protein 2 isoform X1 [KO:K03875 ]
700677 IL12RB2; interleukin-12 receptor subunit beta-2 [KO:K05064 ]
700724 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1 [KO:K04548 ]
701054 GADD45A; growth arrest and DNA damage-inducible protein GADD45 alpha [KO:K04402 ]
701205 HHIP; hedgehog-interacting protein precursor [KO:K06231 ]
701237 IKBKG; NF-kappa-B essential modulator isoform X1 [KO:K07210 ]
701313 LAMA3; laminin subunit alpha-3 isoform X1 [KO:K06240 ]
701584 FGF10; fibroblast growth factor 10 precursor [KO:K04358 ]
701759 TCF7L2; transcription factor 7-like 2 isoform X9 [KO:K04491 ]
701803 SMAD4; mothers against decapentaplegic homolog 4 [KO:K04501 ]
701906 PAX8; paired box protein Pax-8 isoform X6 [KO:K09293 ]
701951 PLCB2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 [KO:K05858 ] [EC:3.1.4.11 ]
702041 GRB2; growth factor receptor-bound protein 2 [KO:K04364 ]
702385 RASSF1; ras association domain-containing protein 1 isoform X1 [KO:K09850 ]
702468 BIRC3; baculoviral IAP repeat-containing protein 3 [KO:K16060 ]
702494 GLI3; transcriptional activator GLI3 isoform X1 [KO:K06230 ]
702504 CAMK2D; calcium/calmodulin-dependent protein kinase type II subunit delta isoform X2 [KO:K04515 ] [EC:2.7.11.17 ]
702592 BIRC2; baculoviral IAP repeat-containing protein 2 [KO:K16060 ]
702727 FGF22; fibroblast growth factor 22 precursor [KO:K04358 ]
702789 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1 [KO:K10131 ]
703173 PDGFB; platelet-derived growth factor subunit B [KO:K17386 ]
703239 TGFB3; transforming growth factor beta-3 precursor [KO:K13377 ]
703398 PTGER3; prostaglandin E2 receptor EP3 subtype isoform X2 [KO:K04260 ]
703399 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 [KO:K04536 ]
703514 CALML6; calmodulin-like protein 6 isoform X1 [KO:K02183 ]
703518 PLEKHG5; pleckstrin homology domain-containing family G member 5 isoform X7 [KO:K19464 ]
703707 COL4A6; collagen alpha-6(IV) chain isoform X1 [KO:K06237 ]
703780 GNAI2; guanine nucleotide-binding protein G(i) subunit alpha-2 [KO:K04630 ]
703814 COL4A5; collagen alpha-5(IV) chain isoform X1 [KO:K06237 ]
703838 RASGRP1; RAS guanyl-releasing protein 1 isoform X3 [KO:K04350 ]
704649 IL5RA; interleukin-5 receptor subunit alpha [KO:K05067 ]
704678 HIF1A; hypoxia-inducible factor 1-alpha isoform X4 [KO:K08268 ]
705404 IL4R; interleukin-4 receptor subunit alpha isoform X2 [KO:K05071 ]
705680 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha [KO:K04634 ]
705864 DVL1; segment polarity protein dishevelled homolog DVL-1 isoform X1 [KO:K02353 ]
705980 CAMK2G; calcium/calmodulin-dependent protein kinase type II subunit gamma [KO:K04515 ] [EC:2.7.11.17 ]
706132 KIF7; kinesin-like protein KIF7 isoform X1 [KO:K18806 ]
706659 FGF17; fibroblast growth factor 17 precursor [KO:K04358 ]
706977 CAMK2B; calcium/calmodulin-dependent protein kinase type II subunit beta isoform X11 [KO:K04515 ] [EC:2.7.11.17 ]
707310 PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma [KO:K02649 ]
707345 APC2; adenomatous polyposis coli protein 2 isoform X1 [KO:K02085 ]
707540 TGFB2; transforming growth factor beta-2 precursor [KO:K13376 ]
707606 NFE2L2; nuclear factor erythroid 2-related factor 2 [KO:K05638 ]
707637 CDC42; cell division control protein 42 homolog [KO:K04393 ]
707725 PDGFA; platelet-derived growth factor subunit A isoform X1 [KO:K04359 ]
708024 PTGER2; prostaglandin E2 receptor EP2 subtype [KO:K04259 ]
708193 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 [KO:K04545 ]
708287 COL4A4; collagen alpha-4(IV) chain isoform X1 [KO:K06237 ]
708431 HSP90AA1; heat shock protein 90kDa alpha (cytosolic), class A member 1 [KO:K04079 ]
708579 RAD51; DNA repair protein RAD51 homolog 1 isoform X1 [KO:K04482 ]
708606 FADD; FAS-associated death domain protein [KO:K02373 ]
708918 FGF3; fibroblast growth factor 3 precursor [KO:K04358 ]
708940 GNAI1; guanine nucleotide-binding protein G(i) subunit alpha-1 isoform X1 [KO:K04630 ]
709209 CDKN2B; cyclin-dependent kinase 4 inhibitor B [KO:K04685 ]
709489 GNB4; guanine nucleotide-binding protein subunit beta-4 [KO:K04538 ]
709509 NCOA4; nuclear receptor coactivator 4 isoform X1 [KO:K09289 ]
709511 CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X3 [KO:K04467 ] [EC:2.7.11.10 ]
709565 BIRC5; baculoviral IAP repeat-containing protein 5 [KO:K08731 ]
709760 STAT5B; signal transducer and activator of transcription 5B isoform X1 [KO:K11224 ]
709947 NOTCH1; neurogenic locus notch homolog protein 1 [KO:K02599 ]
709959 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922 ] [EC:2.7.1.153 ]
710000 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 [KO:K07826 ]
710324 NFKB1; nuclear factor NF-kappa-B p105 subunit [KO:K02580 ]
710540 CAMK2A; calcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1 [KO:K04515 ] [EC:2.7.11.17 ]
710548 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 [KO:K04542 ]
710552 PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1 [KO:K00922 ] [EC:2.7.1.153 ]
710643 FGF23; fibroblast growth factor 23 precursor [KO:K22428 ]
710802 IGF2; insulin-like growth factor II isoform X2 [KO:K13769 ]
710986 IL13RA1; interleukin-13 receptor subunit alpha-1 [KO:K05076 ]
711187 MSH3; DNA mismatch repair protein Msh3 isoform X1 [KO:K08736 ]
711257 GADD45B; growth arrest and DNA damage-inducible protein GADD45 beta [KO:K04402 ]
711335 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 [KO:K04543 ]
711355 SMAD3; mothers against decapentaplegic homolog 3 [KO:K23605 ]
711879 TRAF5; TNF receptor-associated factor 5 isoform X1 [KO:K09849 ]
712010 SPI1; transcription factor PU.1 isoform X3 [KO:K09438 ]
712096 ARHGEF12; rho guanine nucleotide exchange factor 12 isoform X2 [KO:K07532 ]
712444 COL4A3; collagen alpha-3(IV) chain isoform X1 [KO:K06237 ]
712610 ELK1; ETS domain-containing protein Elk-1 [KO:K04375 ]
712627 IL23A; interleukin-23 subunit alpha precursor [KO:K05426 ]
712654 VEGFD; vascular endothelial growth factor D [KO:K05449 ]
712694 STAT2; signal transducer and activator of transcription 2 [KO:K11221 ]
712773 AGTR1; type-1 angiotensin II receptor isoform X2 [KO:K04166 ]
712786 ARNT2; aryl hydrocarbon receptor nuclear translocator 2 isoform X1 [KO:K15589 ]
712788 IL15RA; interleukin-15 receptor subunit alpha isoform 2 precursor [KO:K05074 ]
712988 HEY2; hairy/enhancer-of-split related with YRPW motif protein 2 [KO:K09091 ]
713485 CSF3R; granulocyte colony-stimulating factor receptor isoform X1 [KO:K05061 ]
713777 SOS1; son of sevenless homolog 1 isoform X1 [KO:K03099 ]
713798 NOTCH2; neurogenic locus notch homolog protein 2 precursor [KO:K20994 ]
713904 E2F3; transcription factor E2F3 isoform X1 [KO:K06620 ]
713913 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 [KO:K07825 ]
714159 STAT6; signal transducer and activator of transcription 6 [KO:K11225 ]
714173 PLCG2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 isoform X1 [KO:K05859 ] [EC:3.1.4.11 ]
714381 DVL2; segment polarity protein dishevelled homolog DVL-2 [KO:K02353 ]
714436 RALGDS; ral guanine nucleotide dissociation stimulator isoform X4 [KO:K08732 ]
714641 EPAS1; endothelial PAS domain-containing protein 1 isoform X1 [KO:K09095 ]
714843 GLI1; zinc finger protein GLI1 isoform X1 [KO:K16797 ]
715091 EML4; echinoderm microtubule-associated protein-like 4 isoform X1 [KO:K15420 ]
715394 LAMA2; laminin subunit alpha-2 isoform X1 [KO:K05637 ]
715919 RELA; transcription factor p65 isoform X1 [KO:K04735 ]
715971 ARNT; aryl hydrocarbon receptor nuclear translocator isoform X1 [KO:K09097 ]
716098 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1 [KO:K00922 ] [EC:2.7.1.153 ]
716117 HEYL; hairy/enhancer-of-split related with YRPW motif-like protein [KO:K09091 ]
716364 TRAF4; TNF receptor-associated factor 4 isoform X1 [KO:K09848 ]
716690 IL6R; interleukin-6 receptor subunit alpha isoform X2 [KO:K05055 ]
717153 CEBPA; CCAAT/enhancer-binding protein alpha [KO:K09055 ]
717164 CKS1B; cyclin-dependent kinases regulatory subunit 1 [KO:K02219 ]
717323 NOTCH4; neurogenic locus notch homolog protein 4 isoform X1 [KO:K20996 ]
717368 RXRB; retinoic acid receptor RXR-beta isoform X2 [KO:K08525 ]
717740 BAD; bcl2-associated agonist of cell death [KO:K02158 ]
717755 RAC1; ras-related C3 botulinum toxin substrate 1 isoform X1 [KO:K04392 ]
717764 PLCB3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 [KO:K05858 ] [EC:3.1.4.11 ]
718144 GNA13; guanine nucleotide-binding protein subunit alpha-13 isoform X1 [KO:K04639 ]
718223 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 [KO:K04541 ]
718387 PLCB1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 [KO:K05858 ] [EC:3.1.4.11 ]
718418 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X3 [KO:K05858 ] [EC:3.1.4.11 ]
718632 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X1 [KO:K04345 ] [EC:2.7.11.11 ]
718727 ARHGEF11; rho guanine nucleotide exchange factor 11 isoform X12 [KO:K12331 ]
718751 PTCH1; protein patched homolog 1 isoform X1 [KO:K06225 ]
718861 PPARD; peroxisome proliferator-activated receptor delta isoform X1 [KO:K04504 ]
719119 NOTCH3; neurogenic locus notch homolog protein 3 [KO:K20995 ]
719199 CDKN1A; cyclin-dependent kinase inhibitor 1 [KO:K06625 ]
719239 FLT3LG; fms-related tyrosine kinase 3 ligand isoform X2 [KO:K05454 ]
719248 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 [KO:K04537 ]
719305 RAC3; ras-related C3 botulinum toxin substrate 3 isoform X1 [KO:K07861 ]
719367 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta [KO:K02649 ]
720514 KEAP1; kelch-like ECH-associated protein 1 [KO:K10456 ]
721605 LRP5; low-density lipoprotein receptor-related protein 5 isoform X1 [KO:K03068 ]
721649 GNA11; guanine nucleotide-binding protein subunit alpha-11 [KO:K04635 ]
721712 FLT3; LOW QUALITY PROTEIN: receptor-type tyrosine-protein kinase FLT3 [KO:K05092 ] [EC:2.7.10.1 ]
721821 MAP2K2; dual specificity mitogen-activated protein kinase kinase 2 isoform X1 [KO:K04369 ] [EC:2.7.12.2 ]
721981 BRCA2; LOW QUALITY PROTEIN: breast cancer type 2 susceptibility protein [KO:K08775 ]
722068 RXRA; retinoic acid receptor RXR-alpha isoform X1 [KO:K08524 ]
722115 VEGFB; vascular endothelial growth factor B isoform X2 [KO:K16858 ]
722198 ARHGEF1; rho guanine nucleotide exchange factor 1 isoform X2 [KO:K12330 ]
722398 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 [KO:K04547 ]
722472 LAMA1; LOW QUALITY PROTEIN: laminin subunit alpha-1 [KO:K05637 ]
Compound C00681 1-Acyl-sn-glycerol 3-phosphate
C01245 D-myo-Inositol 1,4,5-trisphosphate
C05981 Phosphatidylinositol-3,4,5-trisphosphate
C16038 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
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Journal Related mcc04060 Cytokine-cytokine receptor interaction
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