 G Protein-coupled receptors
|
Rhodopsin family
|
 Acetylcholine (muscarinic)
|
Adrenaline
|
Dopamine
|
Histamine
|
Serotonin
|
HTR1 [HSA:3350 3351 3352 3354 3355] [KO:K04153]
|
HTR1A [HSA:3350] [KO:K04153]
|
HTR1B [HSA:3351] [KO:K04153]
|
HTR1D [HSA:3352] [KO:K04153]
|
HTR1F [HSA:3355] [KO:K04153]
|
HTR2 [HSA:3356 3357 3358] [KO:K04157]
|
HTR2A [HSA:3356] [KO:K04157]
|
 D00274 Cisapride (USP/INN)
D02092 Cisapride (JAN)
D07945 Fenfluramine (INN)
D04148 Fenfluramine hydrochloride (JAN/USAN) <JP/US>
D02363 Ketanserin (USAN/INN)
D08099 Ketanserin tartrate
D08244 Naftidrofuryl (INN)
D05107 Nafronyl oxalate (USAN)
D07307 Cyamemazine (INN)
D07756 Cyamemazine tartrate
D02671 Mesoridazine (USAN/INN)
D00795 Mesoridazine besylate (USP)
D08385 Pipotiazine (INN)
D02680 Pipotiazine palmitate (USAN)
D11169 Lumateperone (USAN/INN)
D11170 Lumateperone tosylate (USAN) <US>
D00561 Sertindole (USAN/INN)
D08687 Ziprasidone (INN)
D01939 Ziprasidone hydrochloride (USP) <US>
D02100 Ziprasidone mesylate (USAN) <US>
D04820 Lurasidone hydrochloride (JAN/USAN) <JP/US>
D02340 Loxapine (USAN/INN)
D00794 Loxapine succinate (USP) <US>
D08148 Loxapine hydrochloride
D00283 Clozapine (JAN/USP/INN) <JP/US>
D08456 Quetiapine (INN)
D00458 Quetiapine fumarate (JP19/USP) <JP/US>
D11769 Asenapine (INN) <US>
D02995 Asenapine maleate (JAN/USAN) <JP/US>
D00426 Risperidone (JP19/USP/INN) <JP/US>
D08235 Mosapramine (INN)
D01548 Mosapramine hydrochloride (JAN) <JP>
D01164 Aripiprazole (JP19/USP/INN) <JP/US>
D10355 Aripiprazole cavoxil (USAN)
D10364 Aripiprazole lauroxil (USAN) <US>
D10516 Aripiprazole hydrate (JAN) <JP/US>
D05339 Paliperidone (JAN/USP/INN) <JP/US>
D05340 Paliperidone palmitate (JAN/USAN) <JP/US>
D09997 Cariprazine (USAN/INN)
D09876 Cariprazine hydrochloride (JAN/USAN) <US>
D10309 Brexpiprazole (JAN/USAN/INN) <JP/US>
D13183 Brexpiprazole fumarate hydrate (JAN)
D08969 Pimavanserin tartrate (USAN) <US>
D08216 Mianserin (INN)
D01358 Mianserin hydrochloride (JAN/USAN) <JP>
D08257 Nefazodone (INN)
D00819 Nefazodone hydrochloride (USP) <US>
D01176 Blonanserin (JP19/INN) <JP>
D01624 Sarpogrelate hydrochloride (JP19) <JP>
D02372 Perospirone hydrochloride hydrate (JP19) <JP>
D02656 Fananserin (USAN/INN)
D02836 Altanserin tartrate (USAN)
D02893 Amesergide (USAN/INN)
D03005 Atiprosin maleate (USAN)
D04055 Esmirtazapine maleate (USAN)
D04788 Lubazodone hydrochloride (USAN)
D05738 Ritanserin (USAN/INN)
D06632 Pruvanserin (USAN/INN)
D06633 Pruvanserin hydrochloride (USAN)
D08508 Sarpogrelate (INN)
D09645 Nelotanserin (USAN/INN)
D09976 Temanogrel (USAN/INN)
D09977 Temanogrel hydrochloride (USAN)
D10006 Eplivanserin (USAN/INN)
D10329 Zicronapine (USAN/INN)
D10495 Zicronapine succinate (USAN)
D12881 Psilocybin (USAN)
D13135 Deupsilocin besylate (USAN)
D13136 Deupsilocin (USAN/INN)
D13141 Dimethyltryptamine (USAN/INN)
D13268 Deulumateperone (USAN/INN)
D13275 Remlifanserin (USAN/INN)
|
HTR2C [HSA:3358] [KO:K04157]
|
HTR4 [HSA:3360] [KO:K04160]
|
HTR6 [HSA:3362] [KO:K04162]
|
HTR7 [HSA:3363] [KO:K04163]
|
Trace amine
|
Anaphylatoxin
|
Angiotensin
|
Bradykinin
|
Cholecystokinin
|
Endothelin
|
Follicle stimulating hormone
|
Ghrelin
|
GHSR [HSA:2693] [KO:K04284]
|
D10563 Macimorelin (USAN)
D10562 Macimorelin acetate (USAN) <US>
D02040 Pralmorelin dihydrochloride (USAN) <JP>
D03373 Capromorelin tartrate (USAN)
D05734 Rismorelin porcine (USAN)
D08856 Anamorelin hydrochloride (JAN/USAN) <JP>
D09981 Ulimorelin (USAN/INN)
D09982 Ulimorelin hydrochloride (USAN)
D10660 Relamorelin (USAN/INN)
|
Gonadotropin-releasing hormone
|
Lutropin-choriogonadotropic hormone
|
Melanocortin
|
Motilin
|
Neuropeptide Y
|
Opioid
|
Orexin
|
Oxytocin
|
Relaxin
|
RXFP1 [HSA:59350] [KO:K04306]
|
D10488 Serelaxin (USAN/INN)
|
RXFP2 [HSA:122042] [KO:K04307]
|
D12783 Volenrelaxin (USAN)
|
Somatostatin
|
Tachykinin
|
Thrombin
|
Thyrotropin-releasing hormone
|
Vasopressin
|
Purine / pyrimidine
|
Adenosine
|
ADORA [HSA:134 135 136 140] [KO:K04265 K04266 K04267 K04268]
|
ADORA1 [HSA:134] [KO:K04265]
|
ADORA2 [HSA:135 136] [KO:K04266 K04267]
|
ADORA2A [HSA:135] [KO:K04266]
|
D12568 Regadenoson (INN) <US>
D05711 Regadenoson (USAN) <US>
D00528 Caffeine (USP) <JP>
D01453 Caffeine hydrate (JP19) <JP>
D07603 Caffeine citrate (USP) <US>
D04641 Istradefylline (JAN/USAN/INN) <JP/US>
D02017 Oxtriphylline (USP)
D03898 Doxofylline (USAN/INN)
D03120 Binodenoson (USAN/INN)
D03212 Apadenoson (USAN)
D09003 Sonedenoson (USAN)
D09717 Preladenant (USAN/INN)
D09991 Vipadenant (USAN/INN)
D10174 Tozadenant (USAN)
D10362 Evodenoson (USAN/INN)
D11547 Ciforadenant (USAN)
D11978 Inupadenant (USAN)
D11979 Inupadenant hydrochloride (USAN)
|
ADORA2B [HSA:136] [KO:K04267]
|
ADORA3 [HSA:140] [KO:K04268]
|
Cysteinyl leukotriene
|
Free fatty acid
|
Leukotriene
|
Lysophosphatidic acid
|
Oleoylethanolamide
|
Prostaglandin
|
Prostacyclin
|
Sphingolipid
|
Thromboxane
|
Cannabinoid
|
Melatonin
|
Platelet activating factor
|
R-spondin
|
Orphan GPCR
|
Secretin receptor family
|
Metabotropic glutamate receptor family
|
Frizzled / Smoothened family
|
Others
|
|
Ion channels
|
|
Nuclear receptors
|
Thyroid hormone like receptors
|
Thyroid hormone receptor (THR)
|
Retinoic acid receptor (RAR)
|
Peroxisome proliferator-activated receptor (PPAR)
|
RAR-related orphan receptor
|
NR1F3 (RORC) [HSA:6097] [KO:K08534]
|
D12274 Cedirogant (USAN/INN)
|
Liver X receptor like receptor
|
Vitamin D3 like receptor
|
Hepatocyte nuclear factor 4 like receptors
|
Estrogen like receptors
|
Estrogen receptor
|
3-Ketosteroid receptor
|
NR3C1 (GR) [HSA:2908] [KO:K05771]
|
D00385 Triamcinolone (JP19/USP/INN) <JP>
D00983 Triamcinolone acetonide (JP19/USP) <JP/US>
D00984 Triamcinolone diacetate (JAN/USP)
D00985 Triamcinolone hexacetonide (USP/INN)
D06216 Triamcinolone acetonide sodium phosphate (USAN)
D00292 Dexamethasone (JP19/USP/INN) <JP/US>
D00975 Dexamethasone sodium phosphate (JAN/USP) <JP/US>
D01510 Dexamethasone metasulfobenzoate sodium (JAN) <JP>
D01615 Dexamethasone palmitate (JAN) <JP>
D01632 Dexamethasone dipropionate (USAN) <JP>
D01948 Dexamethasone valerate (JAN) <JP>
D02174 Dexamethasone acetate (JAN/USP)
D02591 Dexamethasone acefurate (USAN/INN)
D02592 Dexamethasone beloxil (USAN)
D07073 Dexamethasone cipecilate (JAN/INN) <JP>
D07796 Dexamethasone 21-acetate
D07797 Dexamethasone isonicotinate
D07798 Dexamethasone sodium hemisulfate
D07799 Dexamethasone 21-tebutate
D07800 Dexamethasone 21-valerate
D07801 Dexamethasone phenylpropionate
D07802 Dexamethasone phosphate
D00088 Hydrocortisone (JP19/USP/INN) <JP/US>
D00165 Hydrocortisone acetate (JP19/USP) <US>
D00976 Hydrocortisone cypionate
D00977 Hydrocortisone sodium phosphate (JP19/USP) <JP>
D00978 Hydrocortisone sodium succinate (JP19/USP) <JP/US>
D01442 Hydrocortisone succinate (JP19)
D01619 Hydrocortisone butyrate (JP19/USP) <JP/US>
D01886 Hydrocortisone probutate (USAN) <JP>
D02288 Hydrocortisone valerate (USP) <US>
D04467 Hydrocortisone hemisuccinate (USP)
D06876 Hydrocortisone aceponate (INN)
D09796 Hydrocortisone caproate (JAN)
D00472 Prednisolone (JP19/USP/INN) <JP/US>
D00980 Prednisolone acetate (JP19/USP/INN) <JP/US>
D00981 Prednisolone sodium phosphate (JP19/USP) <US>
D00982 Prednisolone tebutate (JAN/USP)
D01239 Prednisolone sodium succinate (JP19/USP) <JP>
D01998 Prednisolone farnesylate (JAN)
D02156 Prednisolone hemisuccinate (USP)
D03301 Prednisolone valerate acetate (JAN) <JP>
D08412 Prednisolone pivalate
D08413 Prednisolone sodium metazoate (USAN)
D08414 Prednisolone 21-(sodium tetrahydrophthalate)
D08415 Prednisolone steaglate (BAN)
D00473 Prednisone (USP) <US>
D08416 Prednisone acetate
D00244 Betamethasone (JP19/USP/INN) <JP>
D00972 Betamethasone sodium phosphate (JP19/USP) <JP>
D01357 Betamethasone valerate (JP19/USP) <JP/US>
D01402 Betamethasone acetate (JAN/USP)
D01637 Betamethasone dipropionate (JP19/USP) <JP/US>
D02032 Betamethasone butyrate propionate (JAN) <JP>
D02286 Betamethasone benzoate (USP)
D08610 Tixocortol (INN)
D06171 Tixocortol pivalate (USAN)
D00246 Budesonide (JP19/USP/INN) <JP/US>
D07495 Beclometasone (INN)
D00689 Beclomethasone dipropionate (USP) <JP/US>
D11572 Beclomethasone dipropionate monohydrate
D01367 Fluorometholone (JP19/USP/INN) <JP/US>
D04221 Fluorometholone acetate (USP) <US>
D04218 Fluocortolone (USAN/INN)
D04219 Fluocortolone caproate (USAN)
D07973 Fluocortolone 21-pivalate
D01825 Fluocinolone acetonide (JP19/USP/INN) <JP/US>
D00325 Fluocinonide (JP19/USP/INN) <JP/US>
D00407 Methylprednisolone (JP19/USP/INN) <JP/US>
D00751 Methylprednisolone sodium succinate (JAN/USP) <JP/US>
D00979 Methylprednisolone acetate (JAN/USP) <JP/US>
D05000 Methylprednisolone hemisuccinate (USP)
D05001 Methylprednisolone sodium phosphate (USAN)
D05002 Methylprednisolone suleptanate (USAN/INN)
D07203 Methylprednisolone aceponate (INN)
D07717 Clobetasone (INN)
D01273 Clobetasone butyrate (JAN/USAN) <JP>
D04208 Flumethasone (USAN)
D01464 Flumethasone pivalate (USP)
D07972 Fluocortin (INN)
D04217 Fluocortin butyl (USAN)
D07201 Fluprednidene (INN)
D07980 Fluprednidene acetate
D03696 Desonide (USP/INN) <US>
D07116 Alclometasone (INN)
D01820 Alclometasone dipropionate (JAN/USP) <JP/US>
D07719 Clocortolone (INN)
D02287 Clocortolone pivalate (USP) <US>
D03541 Clocortolone acetate (USAN)
D04201 Flucloronide (USAN)
D03697 Desoximetasone (USP/INN) <US>
D03812 Diflucortolone (USAN)
D01764 Diflucortolone valerate (JP19) <JP>
D03813 Diflucortolone pivalate (USAN)
D00328 Flurandrenolide (USP) <US>
D07827 Diflorasone (INN)
D01327 Diflorasone diacetate (JP19/USP) <JP/US>
D01387 Amcinonide (JAN/USP/INN) <JP/US>
D07202 Halometasone (INN)
D08227 Mometasone (INN)
D00690 Mometasone furoate (JAN/USP) <JP/US>
D03325 Mometasone furoate hydrate (JAN) <JP/US>
D07981 Fluticasone (INN)
D01708 Fluticasone propionate (JAN/USP) <JP/US>
D06315 Fluticasone furoate (JAN/USAN/INN) <JP/US>
D05601 Prednicarbate (USP/INN)
D01266 Difluprednate (JAN/USAN/INN) <JP/US>
D08660 Ulobetasol (INN)
D04409 Halobetasol propionate (USP) <US>
D07715 Clobetasol (INN)
D01272 Clobetasol propionate (JP19/USP) <JP/US>
D01308 Halcinonide (JAN/USP/INN) <US>
D00585 Mifepristone (JAN/USAN/INN) <US>
D07464 Paramethasone (INN)
D01229 Paramethasone acetate (JAN/USAN)
D07749 Cortisone (INN)
D00973 Cortisone acetate (JP19/USP) <JP/US>
D07230 Prednylidene (INN)
D05729 Rimexolone (USP/INN)
D03671 Deflazacort (USAN/INN) <US>
D03561 Cloprednol (USAN/INN)
D06673 Meprednisone (USP/INN)
D03594 Cortivazol (USAN)
D11000 Vamorolone (USAN/INN) <US>
D00324 Flunisolide (JAN/USP) <US>
D04214 Flunisolide acetate (USAN)
D01703 Ciclesonide (JAN/USAN/INN) <JP/US>
D02289 Medrysone (USAN)
D04244 Formocortal (USAN/INN)
D08147 Loteprednol (INN)
D01689 Loteprednol etabonate (JAN/USAN) <US>
D01434 Deprodone propionate (JAN) <JP>
D01743 Halopredone acetate (JAN/USAN)
D03691 Descinolone acetonide (USAN)
D04227 Fluprednisolone (USAN/INN)
D04228 Fluprednisolone valerate (USAN)
D05194 Nivazol (USAN)
D05603 Prednival (USAN)
D05719 Resocortol butyrate (USAN)
D06135 Ticabesone propionate (USAN)
D06161 Tipredane (USAN)
D06201 Tralonide (USAN/INN)
D07814 Dichlorisone (INN)
D07815 Dichlorisone acetate
D07975 Flupamesone
D08036 Halopredone (INN)
D08429 Proligestone (INN)
D08476 Resocortol (INN)
D10136 Mapracorat (USAN)
D10617 Dagrocorat (USAN/INN)
D10634 Fosdagrocorat (USAN/INN)
D11336 Relacorilant (USAN) <US>
D11665 Exicorilant (USAN/INN)
D11667 Miricorilant (USAN/INN)
D11937 Velsecorat (USAN/INN)
D12638 Dazucorilant (USAN/INN)
|
NR3C2 (MR) [HSA:4306] [KO:K08555]
|
NR3C3 (PGR) [HSA:5241] [KO:K08556]
|
NR3C4 (AR) [HSA:367] [KO:K08557]
|
|
Protein kinases
|
Serine/threonine kinases
|
Receptor serine/threonine kinases (RSTK)
|
Receptor tyrosine kinases (RTK)
|
Non-receptor tyrosine kinases
|
SRC family
|
ABL family
|
SYK family
|
JAK family
|
FAK family
|
TEC family
|
BTK [HSA:695] [KO:K07370]
|
D10223 Ibrutinib (JAN/USAN) <JP/US>
D10893 Acalabrutinib (JAN/USAN/INN) <JP/US>
D11720 Acalabrutinib maleate (USAN)
D12704 Acalabrutinib maleate hydrate (JAN) <JP/US>
D11422 Zanubrutinib (JAN/USAN/INN) <JP/US>
D12160 Orelabrutinib (USAN/INN)
D12050 Pirtobrutinib (JAN/USAN) <JP/US>
D12594 Tirabrutinib (USAN/INN)
D11070 Tirabrutinib hydrochloride (JAN/USAN) <JP>
D12285 Remibrutinib (JAN/USAN/INN) <JP/US>
D12213 Tolebrutinib (JAN/USAN/INN)
D10730 Spebrutinib (USAN/INN)
D10731 Spebrutinib besylate (USAN)
D11428 Vecabrutinib (USAN/INN)
D11457 Fenebrutinib (USAN/INN)
D11478 Branebrutinib (USAN)
D11502 Vecabrutinib succinate (USAN)
D11873 Rilzabrutinib (JAN/USAN/INN) <JP/US>
D12052 Luxeptinib (USAN)
D12158 Elsubrutinib (USAN/INN)
D12383 Edralbrutinib (USAN/INN)
D12467 Evobrutinib (USAN/INN)
D12489 Atuzabrutinib (USAN/INN)
D12504 Nemtabrutinib (USAN/INN)
D12858 Zelebrudomide (USAN)
D13115 Bexobrutideg (USAN)
D13142 Docirbrutinib (USAN/INN)
D13143 Docirbrutinib mesylate (USAN)
D13253 Birelentinib (USAN/INN)
D13261 Corubrutinib (USAN)
D13277 Flixebrutinib (USAN)
|
ITK [HSA:3702] [KO:K07363]
|
|
Peptidases and inhibitors
|
Aspartic peptidases
|
Cysteine peptidases
|
Papain family
|
CTSC (DPP1) [HSA:1075] [KO:K01275]
|
CTSK [HSA:1513] [KO:K01371]
|
D06634 Relacatib (USAN/INN)
D08955 Odanacatib (JAN/USAN)
|
CTSL [HSA:1514] [KO:K01365]
|
CTSS [HSA:1520] [KO:K01368]
|
Caspase family
|
Metallo peptidases
|
Serine peptidases
|
Chymotrypsin family
|
Subtilisin family
|
Prolyl oligopeptidase family
|
DPP4 (CD26) [HSA:1803] [KO:K01278]
|
D08516 Sitagliptin (USAN/INN) <US>
D06645 Sitagliptin phosphate (USAN) <JP/US>
D12294 Sitagliptin phosphate (JAN)
D13055 Sitagliptin hydrochloride <US>
D07080 Vildagliptin (JAN/USAN/INN) <JP>
D08996 Saxagliptin (USAN/INN)
D09753 Saxagliptin hydrate (JAN) <JP/US>
D10262 Saxagliptin hydrochloride <US>
D06553 Alogliptin benzoate (JAN/USAN) <JP/US>
D09566 Linagliptin (JAN/USAN/INN) <JP/US>
D12703 Linagliptin hydrate (JAN)
D10502 Gemigliptin (INN)
D11023 Evogliptin (INN)
D08616 Teneligliptin (INN)
D09756 Teneligliptin hydrobromide hydrate (JAN) <JP>
D11968 Teneligliptin hydrobromide (JAN)
D06578 Denagliptin tosylate (USAN)
D08631 Carmegliptin (USAN/INN)
D09326 Carmegliptin dihydrochloride (USAN)
D09333 Dutogliptin (USAN)
D09334 Dutogliptin tartrate (USAN)
D09625 Gosogliptin (USAN/INN)
D09780 Anagliptin (JAN/INN) <JP>
D10178 Trelagliptin (USAN)
D10179 Trelagliptin succinate (JAN/USAN) <JP>
D10317 Omarigliptin (JAN/USAN/INN) <JP>
|
DPP8 [HSA:54878] [KO:K08655]
|
DPP9 [HSA:91039] [KO:K08656]
|
ClpP endopeptidase family
|
Family S53
|
Threonine peptidases
|
Peptidase inhibitors
|
Other related factors
|
Complement and coagulation
|
F8 [HSA:2157] [KO:K03899]
|
D00291 Desmopressin (INN)
D02235 Desmopressin acetate (USP) <JP/US>
|
F8* [HSA_VAR:2157v1] [HSA:2157] [KO:K03899]
|
D08798 Freeze-dried human blood-coagulation factor VIII <JP>
D05401 Octocog alfa (INN)
D05409 Rurioctocog alfa (genetical recombination) (JAN) <JP>
D08232 Moroctocog alfa (INN)
D10227 Turoctocog alfa (INN) <JP>
D10539 Efraloctocog alfa (genetical recombination) (JAN) <JP>
D10758 Turoctocog alfa pegol (genetical recombination) (JAN) <JP>
D10759 Damoctocog alfa pegol (INN) <JP>
D10760 Rurioctocog alfa pegol (genetical recombination) (JAN) <JP>
D10771 Octocog beta (genetical recombination) (JAN) <JP>
D10818 Lonoctocog alfa (INN) <JP>
D10830 Efmoroctocog alfa (INN)
D10831 Susoctocog alfa (INN) <JP>
D10842 Simoctocog alfa (INN) <JP>
D12441 Efanesoctocog alfa (INN) <JP>
D12434 Valoctocogene roxaparvovec (USAN/INN)
|
VWF [HSA:7450] [KO:K03900]
|
D11160 Caplacizumab (USAN/INN) <JP/US>
D09892 Egaptivon pegol (USAN)
D12863 Rondaptivon pegol
|
VWF* [HSA_VAR:7450v1] [HSA:7450] [KO:K03900]
|
D08798 Freeze-dried human blood-coagulation factor VIII <JP>
|
GP6 [HSA:51206] [KO:K06264]
|
D12413 Glenzocimab (USAN/INN)
|
CFP [HSA:5199] [KO:K15412]
|
D12823 Tarperprumig (USAN/INN)
|
C1Q [HSA:712 713 714] [KO:K03986 K03987 K03988]
|
D13263 Vonaprument (USAN)
|
C1QRS [HSA:712 713 714 715 716] [KO:K03986 K03987 K03988 K01330 K01331]
|
D13328 Pegtarazimod (USAN/INN)
D13329 Pegtarazimod hydrochloride (USAN)
|
|
Signaling molecules and receptors
|
|
Cell surface molecules and ligands
|
Cell adhesion molecules: Ig superfamiy
|
Cell adhesion molecules: other families
|
Other cell surface molecules
|
Immune checkpoints
|
CTLA4 (CD152) [HSA:1493] [KO:K06538]
|
PDCD1 (PD1, CD279) [HSA:5133] [KO:K06744]
|
PDL1 (CD274) [HSA:29126] [KO:K06745]
|
LAG3 (CD223) [HSA:3902] [KO:K06565]
|
D11350 Relatlimab (USAN)
D12156 Ieramilimab (USAN/INN)
D12317 Bavunalimab (USAN/INN)
D12469 Favezelimab (USAN/INN)
D12480 Tuparstobart (USAN/INN)
D12961 Tobemstomig (USAN/INN)
|
TIGIT [HSA:201633] [KO:K16350]
|
B7H4 (VTCN1) [HSA:79679] [KO:K06747]
|
CD molecules
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Other
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Transporters
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Enzymes
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Oxidoreductases (EC1)
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Dehydrogenases [EC:1.1.1.-]
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Oxidases [EC:1.1.3.-]
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Dehydrogenases [EC:1.2.1.-]
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Dehydrogenases [EC:1.3.-.-]
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Amine oxidases [EC:1.4.3.-]
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Dihydrofolate reductase [EC:1.5.1.3]
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NAD(P)H dehydrogenase [EC:1.6.5.2]
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Peroxidase [EC:1.11.1.-]
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Peroxygenase [EC:1.11.2.-]
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Dioxygenases [EC:1.13.11.-]
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Prolyl 4-hydroxylase [EC:1.14.11.2]
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HIF hydroxylase [EC:1.14.11.29]
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Nitic oxide synthase [EC:1.14.13.39]
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Cytochrome P450 [EC:1.14.14.-]
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Other monooxygenases [EC:1.14.16.- 1.14.17.- 1.14.18.-]
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Prostaglandin synthase [EC:1.14.99.1]
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PTGS1 (COX1) [HSA:5742] [KO:K00509]
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D07516 Benzydamine (INN)
D01410 Benzydamine hydrochloride (JAN/USAN)
D07517 Benzydamine salicylate
D00109 Aspirin (JP19/USP) <JP>
D05181 Aspirin aluminum (JP19)
D07579 Aspirin calcium salt
D07580 Aspirin DL-lysine (JAN)
D07581 Aspirin magnesium salt
D07582 Aspirin sodium
D12595 Aspirin trelamine (USAN)
D12596 Aspirin trelamine hydrochloride (USAN)
D07141 Indobufen (INN)
D07421 Aloxiprin (INN)
D07142 Triflusal (INN)
D00141 Indomethacin (USP) <JP/US>
D01565 Indometacin farnesil (JAN) <JP>
D02110 Indomethacin sodium (USP) <JP>
D00126 Ibuprofen (JP19/USP/INN) <JP/US>
D01122 Ibuprofen piconol (JP19/USAN) <JP>
D04490 Ibuprofen aluminum (USAN)
D06606 Ibuprofen lysine (USAN) <JP/US>
D08058 Ibuprofen arginine salt
D08059 Ibuprofen sodium
D09760 Ibuprofen sodium (USAN)
D12597 Ibuprofen trelamine (USAN)
D12598 Ibuprofen trelamine hydrochloride (USAN)
D08501 Trolamine salicylate (USP)
D07816 Diclofenac (USAN/INN)
D00903 Diclofenac potassium (USP) <US>
D00904 Diclofenac sodium (JP19/USP) <JP/US>
D07817 Diclofenac diethylamine
D07818 Diclofenac epolamine <US>
D07819 Diclofenac calcium
D00118 Naproxen (JP19/USP/INN) <JP/US>
D00970 Naproxen sodium (USP) <US>
D10017 Naproxen etemesil (USAN)
D00510 Phenylbutazone (JP19/USP/INN)
D08363 Phenylbutazone calcium
D08364 Phenylbutazone sodium
D08324 Oxyphenbutazone (INN)
D05319 Oxyphenbutazone hydrate
D00120 Sulindac (JP19/USP/INN) <US>
D02355 Tolmetin (USAN/INN)
D00158 Tolmetin sodium (JAN/USP) <US>
D01582 Acemetacin (JP19/INN) <JP>
D08427 Proglumetacin (INN)
D01765 Proglumetacin maleate (JAN)
D08104 Ketorolac (INN)
D00813 Ketorolac tromethamine (USP) <US>
D01545 Aceclofenac (JAN/INN)
D01271 Bufexamac (JAN/INN)
D00127 Piroxicam (JP19/USP/INN) <US>
D05511 Piroxicam betadex (USAN)
D05512 Piroxicam cinnamate (USAN)
D05513 Piroxicam olamine (USAN)
D01767 Tenoxicam (JAN/USAN/INN)
D07267 Droxicam (INN)
D01866 Lornoxicam (JP19/USAN/INN) <JP>
D00132 Ketoprofen (JP19/USP/INN) <JP/US>
D08102 Ketoprofen lysine
D08103 Ketoprofen sodium
D02350 Fenoprofen (USAN/INN)
D00968 Fenoprofen calcium (JAN/USP) <US>
D01344 Fenbufen (JP19/USAN/INN)
D00330 Flurbiprofen (JP19/USP/INN) <JP/US>
D01475 Flurbiprofen axetil (JAN) <JP>
D02290 Flurbiprofen sodium (USP) <US>
D10254 Esflurbiprofen (JAN/USAN)
D01325 Tiaprofenic acid (JAN/INN)
D00463 Oxaprozin (JP19/USP/INN) <JP/US>
D07268 Ibuproxam (INN)
D03715 Dexibuprofen (USAN/INN)
D03718 Dexibuprofen lysine (USAN)
D01513 Alminoprofen (JP19/INN)
D07269 Dexketoprofen (INN)
D09568 Naproxcinod (USAN/INN)
D08149 Loxoprofen (INN)
D01709 Loxoprofen sodium hydrate (JP19) <JP>
D00151 Mefenamic acid (JP19/USP/INN) <JP/US>
D01183 Tolfenamic acid (JAN/INN)
D01581 Flufenamic acid (JAN/USAN/INN)
D01823 Ufenamate (JAN/INN) <JP>
D03254 Flufenamate aluminum (JAN)
D02341 Meclofenamic acid (USAN/INN)
D00169 Meclofenamate sodium (USP) <US>
D08162 Meclofenamate sodium
D00425 Nabumetone (JP19/USP/INN) <JP/US>
D06072 Tenidap (USAN/INN)
D06073 Tenidap sodium (USAN)
D04102 Etofenamate (USAN/INN)
D01675 Felbinac (JP19/USAN/INN) <JP>
D01841 Felbinac ethyl (JAN)
D08374 Piketoprofen (INN)
D08375 Piketoprofen hydrochloride
D00810 Choline salicylate (JAN/USAN/INN)
D00566 Sodium salicylate (JP19/USP) <JP>
D01811 Salicylamide (JAN/USP/INN)
D00428 Salsalate (USP/INN)
D00217 Acetaminophen (JP19/USP) <JP/US>
D07294 Propacetamol (INN)
D08434 Propacetamol hydrochloride
D01578 Pranoprofen (JP19/INN) <JP>
D05143 Nepafenac (JAN/USAN/INN) <JP/US>
D07541 Bromfenac (INN)
D03163 Bromfenac sodium (USAN) <JP/US>
D00827 Magnesium salicylate (USP)
D01090 Pamicogrel (JAN/INN)
D01397 Ampiroxicam (JP19/INN)
D01527 Epidihydrocholesterin (JAN)
D01547 Zaltoprofen (JP19/INN) <JP>
D01557 Glycol salicylate (JAN)
D01718 Mofezolac (JAN/INN)
D01788 Amfenac sodium (USAN)
D03410 Carprofen (USP/INN)
D05275 Orpanoxin (USAN/INN)
D05451 Phenbutazone sodium glycerate (USAN)
D05598 Pravadoline maleate (USAN)
D05791 Salicylate meglumine (USAN)
D06017 Tebufelone (USAN/INN)
D06364 Zidometacin (USAN/INN)
D07443 Amfenac (INN)
D07453 Amtolmetin guacil (INN)
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PTGS2 (COX2) [HSA:5743] [KO:K11987]
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D07516 Benzydamine (INN)
D01410 Benzydamine hydrochloride (JAN/USAN)
D07517 Benzydamine salicylate
D00109 Aspirin (JP19/USP) <JP>
D05181 Aspirin aluminum (JP19)
D07579 Aspirin calcium salt
D07580 Aspirin DL-lysine (JAN)
D07581 Aspirin magnesium salt
D07582 Aspirin sodium
D12595 Aspirin trelamine (USAN)
D12596 Aspirin trelamine hydrochloride (USAN)
D07141 Indobufen (INN)
D07421 Aloxiprin (INN)
D00141 Indomethacin (USP) <JP/US>
D01565 Indometacin farnesil (JAN) <JP>
D02110 Indomethacin sodium (USP) <JP>
D00126 Ibuprofen (JP19/USP/INN) <JP/US>
D01122 Ibuprofen piconol (JP19/USAN) <JP>
D04490 Ibuprofen aluminum (USAN)
D06606 Ibuprofen lysine (USAN) <JP/US>
D08058 Ibuprofen arginine salt
D08059 Ibuprofen sodium
D09760 Ibuprofen sodium (USAN)
D12597 Ibuprofen trelamine (USAN)
D12598 Ibuprofen trelamine hydrochloride (USAN)
D08501 Trolamine salicylate (USP)
D07816 Diclofenac (USAN/INN)
D00903 Diclofenac potassium (USP) <US>
D00904 Diclofenac sodium (JP19/USP) <JP/US>
D07817 Diclofenac diethylamine
D07818 Diclofenac epolamine <US>
D07819 Diclofenac calcium
D00118 Naproxen (JP19/USP/INN) <JP/US>
D00970 Naproxen sodium (USP) <US>
D10017 Naproxen etemesil (USAN)
D00567 Celecoxib (JP19/USP/INN) <JP/US>
D00510 Phenylbutazone (JP19/USP/INN)
D08363 Phenylbutazone calcium
D08364 Phenylbutazone sodium
D08324 Oxyphenbutazone (INN)
D05319 Oxyphenbutazone hydrate
D00120 Sulindac (JP19/USP/INN) <US>
D02355 Tolmetin (USAN/INN)
D00158 Tolmetin sodium (JAN/USP) <US>
D01252 Alclofenac (JAN/USP/INN)
D00315 Etodolac (JP19/USP/INN) <JP/US>
D01582 Acemetacin (JP19/INN) <JP>
D08427 Proglumetacin (INN)
D01765 Proglumetacin maleate (JAN)
D08104 Ketorolac (INN)
D00813 Ketorolac tromethamine (USP) <US>
D01545 Aceclofenac (JAN/INN)
D01271 Bufexamac (JAN/INN)
D00127 Piroxicam (JP19/USP/INN) <US>
D05511 Piroxicam betadex (USAN)
D05512 Piroxicam cinnamate (USAN)
D05513 Piroxicam olamine (USAN)
D01767 Tenoxicam (JAN/USAN/INN)
D07267 Droxicam (INN)
D01866 Lornoxicam (JP19/USAN/INN) <JP>
D00969 Meloxicam (JAN/USP/INN) <JP/US>
D00132 Ketoprofen (JP19/USP/INN) <JP/US>
D08102 Ketoprofen lysine
D08103 Ketoprofen sodium
D02350 Fenoprofen (USAN/INN)
D00968 Fenoprofen calcium (JAN/USP) <US>
D01344 Fenbufen (JP19/USAN/INN)
D00330 Flurbiprofen (JP19/USP/INN) <JP/US>
D01475 Flurbiprofen axetil (JAN) <JP>
D02290 Flurbiprofen sodium (USP) <US>
D10254 Esflurbiprofen (JAN/USAN)
D01325 Tiaprofenic acid (JAN/INN)
D00463 Oxaprozin (JP19/USP/INN) <JP/US>
D07268 Ibuproxam (INN)
D03715 Dexibuprofen (USAN/INN)
D03718 Dexibuprofen lysine (USAN)
D01513 Alminoprofen (JP19/INN)
D07269 Dexketoprofen (INN)
D09568 Naproxcinod (USAN/INN)
D08149 Loxoprofen (INN)
D01709 Loxoprofen sodium hydrate (JP19) <JP>
D00151 Mefenamic acid (JP19/USP/INN) <JP/US>
D01183 Tolfenamic acid (JAN/INN)
D01581 Flufenamic acid (JAN/USAN/INN)
D01823 Ufenamate (JAN/INN) <JP>
D03254 Flufenamate aluminum (JAN)
D02341 Meclofenamic acid (USAN/INN)
D00169 Meclofenamate sodium (USP) <US>
D08162 Meclofenamate sodium
D00568 Rofecoxib (JAN/USAN/INN)
D02709 Valdecoxib (USAN/INN)
D03716 Parecoxib (USAN/INN)
D03717 Parecoxib sodium (USAN)
D03710 Etoricoxib (USAN/INN)
D03714 Lumiracoxib (USAN/INN)
D10656 Polmacoxib (USAN/INN)
D00425 Nabumetone (JP19/USP/INN) <JP/US>
D08275 Niflumic acid (INN)
D01049 Nimesulide (JAN/INN)
D06072 Tenidap (USAN/INN)
D06073 Tenidap sodium (USAN)
D04102 Etofenamate (USAN/INN)
D01675 Felbinac (JP19/USAN/INN) <JP>
D01841 Felbinac ethyl (JAN)
D08374 Piketoprofen (INN)
D08375 Piketoprofen hydrochloride
D00810 Choline salicylate (JAN/USAN/INN)
D00566 Sodium salicylate (JP19/USP) <JP>
D01811 Salicylamide (JAN/USP/INN)
D00428 Salsalate (USP/INN)
D00130 Diflunisal (JAN/USP/INN) <US>
D00217 Acetaminophen (JP19/USP) <JP/US>
D07294 Propacetamol (INN)
D08434 Propacetamol hydrochloride
D01578 Pranoprofen (JP19/INN) <JP>
D05143 Nepafenac (JAN/USAN/INN) <JP/US>
D07541 Bromfenac (INN)
D03163 Bromfenac sodium (USAN) <JP/US>
D00827 Magnesium salicylate (USP)
D01090 Pamicogrel (JAN/INN)
D01397 Ampiroxicam (JP19/INN)
D01547 Zaltoprofen (JP19/INN) <JP>
D01557 Glycol salicylate (JAN)
D01788 Amfenac sodium (USAN)
D01974 Tilmacoxib (JAN/USAN/INN)
D03410 Carprofen (USP/INN)
D03652 Darbufelone mesylate (USAN)
D03689 Deracoxib (USAN)
D03712 Firocoxib (USAN/INN)
D04863 Mavacoxib (USAN)
D05275 Orpanoxin (USAN/INN)
D05451 Phenbutazone sodium glycerate (USAN)
D05598 Pravadoline maleate (USAN)
D05791 Salicylate meglumine (USAN)
D06017 Tebufelone (USAN/INN)
D06364 Zidometacin (USAN/INN)
D07443 Amfenac (INN)
D07453 Amtolmetin guacil (INN)
D07888 Eltenac (INN)
D08657 Apricoxib (USAN/INN)
D11020 Diclofenac etalhyaluronate sodium (JAN) <JP>
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Histone demethylase [EC:1.14.99.66]
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Superoxide dismutase [EC:1.15.1.1]
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Xanthine dehydrogenase/oxidase [EC:1.17.1.4 1.17.3.2]
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Ribonucleoside-diphosphate reductase [EC:1.17.4.1]
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Vitamin-K-epoxide reductase [EC:1.17.4.4]
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Thyroxine 5'-deiodinase [EC:1.21.99.4]
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Transferases (EC2)
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Hydrolases (EC3)
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Carboxylic-ester hydrolases [EC:3.1.1.-]
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Phosphatases [EC:3.1.3.-]
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Phosphodiesterases [EC:3.1.4.-]
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SMPD1* [HSA_VAR:6609v1] [HSA:6609] [KO:K12350]
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PDE [HSA:10846 27115 50940 5136 5137 5138 5139 5140 5141 5142 5143 5144 5150 5151 5153 8622] [KO:K18438 K18436 K13298 K13755 K18283 K19021 K13296 K13293 K18437]
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D07425 Papaverine (BAN)
D02218 Papaverine hydrochloride (JP19/USP) <JP>
D07439 Papaverine sulfate
D07089 Moxaverine (INN)
D08238 Moxaverine hydrochloride
D07546 Bucladesine (INN)
D01238 Bucladesine sodium (JAN) <JP>
D01220 Trapidil (JP19/INN) <JP>
D07961 Flavoxate (INN)
D00718 Flavoxate hydrochloride (JP19/USP) <JP/US>
D00691 Dyphylline (USP) <JP>
D02017 Oxtriphylline (USP)
D01771 Proxyphylline (JAN/INN)
D00371 Theophylline (JP19) <JP/US>
D01712 Theophylline sodium acetate (JAN)
D06103 Theophylline (USP)
D06104 Theophylline sodium glycinate (USP)
D00227 Aminophylline (USP/INN)
D05429 Aminophylline hydrate (JP19) <JP>
D11630 Aminophylline dihydrate <US>
D03075 Bemoradan (USAN/INN)
D04006 Enprofylline (USAN/INN)
D05278 Oxagrelate (USAN/INN)
D05612 Prinoxodan (USAN/INN)
D06132 Tibenelast sodium (USAN)
D09822 Theosalicin (JAN)
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PDE [HSA:5153 5138 5139 5140 5141 5142 5143 5144 8654] [KO:K13755 K18283 K19021 K13296 K13293 K13762]
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PDE1 [HSA:5136 5153 5137] [KO:K13755]
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PDE2A [HSA:5138] [KO:K18283]
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PDE3 [HSA:5139 5140] [KO:K19021 K13296]
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PDE4 [HSA:5141 5142 5143 5144] [KO:K13293]
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PDE4A [HSA:5141] [KO:K13293]
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PDE4B [HSA:5142] [KO:K13293]
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PDE4D [HSA:5144] [KO:K13293]
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PDE5 [HSA:8654] [KO:K13762]
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PDE9 [HSA:5152] [KO:K13761]
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PDE10A [HSA:10846] [KO:K18438]
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ENPP2 (ATX) [HSA:5168] [KO:K01122]
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Sulfatases [EC:3.1.6.-]
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Glycosidases [EC:3.2.1.-]
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ADP-ribosyl cyclase [EC:3.2.2.6]
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Glutaminase [EC:3.5.1.2]
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Histone deacetylase [EC:3.5.1.98]
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Fatty acid amide hydrolase [EC:3.5.1.99]
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Arginase [EC:3.5.3.1]
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Adenosine deaminase [EC:3.5.4.4]
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Cytidine deaminase [EC:3.5.4.5]
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ATPase [EC:3.6.3.-]
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Lyases (EC4)
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Isomerases (EC5)
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Peptidylprolyl isomerase [EC:5.2.1.8]
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Prostaglandin-E synthase [EC:5.3.99.3]
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Thromboxane-A synthase [EC:5.3.99.5]
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TBXAS1 (CYP5A1) [HSA:6916] [KO:K01832]
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D07140 Picotamide (BAN)
D01220 Trapidil (JP19/INN) <JP>
D01683 Ozagrel hydrochloride hydrate (JAN) <JP>
D01684 Ozagrel sodium (JP19) <JP>
D03661 Dazmegrel (USAN/INN)
D03663 Dazoxiben hydrochloride (USAN)
D04276 Furegrelate sodium (USAN)
D05502 Pirmagrel (USAN/INN)
D05727 Ridogrel (USAN/INN)
D06077 Terbogrel (USAN/INN)
D08327 Ozagrel (INN)
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DNA topoisomerase [EC:5.99.1.-]
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Ligases (EC6)
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Nucleic acids
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Not elsewhere classified
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Genetic information processing
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Transcription factor
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NFE2L2 [HSA:4780] [KO:K05638]
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AHR [HSA:196] [KO:K09093]
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HIF1A [HSA:3091] [KO:K08268]
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HIF2A (EPAS1) [HSA:2034] [KO:K09095]
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MYC [HSA:4609] [KO:K04377]
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SP1 [HSA:6667] [KO:K04684]
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EGR1 [HSA:1958] [KO:K09203]
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WT1 (WT33) [HSA:7490] [KO:K09234]
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BCL6 [HSA:604] [KO:K15618]
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NANOG [HSA:79923] [KO:K10164]
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NFKB1 [HSA:4790] [KO:K02580]
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STAT3 [HSA:6774] [KO:K04692]
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TP53 (p53) [HSA:7157] [KO:K04451]
|
TP53* (p53) [HSA_VAR:7157v1] [HSA:7157] [KO:K04451]
|
RELA (NKFB3, p65) [HSA:5970] [KO:K04735]
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D12181 Edasalonexent (USAN/INN)
|
IKZF1/3 [HSA:10320 22806] [KO:K09220]
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Translation factor
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Chaperone and folding catalyst
|
Spliceosome
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Environmental information processing
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Cellular process
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Organismal systems
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Unclassified
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Target-based Classification of Drugs