KEGG image  Pharmacogenomic Biomarkers

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Somatic variations in targeted cancer therapies

Drug KEGG
DRUG
ATC Product Target Biomarker KEGG
VARIANT
KEGG
NETWORK
Rituximab D02994 L01XC02 Rituxan CD20 CD20 positive
Trastuzumab D03257 L01XC03 Herceptin HER2 HER2 overexpression 2064v1 nt06270
nt06261
Gemtuzumab ozogamicin D03259 L01XC05 Mylotarg CD33 CD33 positive
Cetuximab D03455 L01XC06 Erbitux EGFR EGFR expression, KRAS wild type
Panitumumab D05350 L01XC08 Vectibix EGFR EGFR expression, KRAS wild type
Ofatumumab D09314 L01XC10 Arzerra CD20 CD20 positive
Ipilimumab D04603 L01XC11 Yervoy CTLA4 Microsatellite instability-high (MSI-H) or mismatch repair deficiency (dMMR)
Brentuximab vedotin D09587 L01XC12 Adcetris CD30 CD30 positive
Pertuzumab D05446 L01XC13 Perjeta HER2 HER2 positive 2064v1
2064v3
nt06270
Trastuzumab emtansine D09980 L01XC14 Kadcyla HER2 HER2 positive 2064v1
2064v3
nt06270
Obinutuzumab D09321 L01XC15 Gazyva CD20 CD20 positive
Dinutuximab D10559 L01XC16 Unituxin GD2 MYCN amplification
Nivolumab D10316 L01XC17 Opdivo PD1 PDL1 positive
BRAF V600
Microsatellite instability-high (MSI-H) or mismatch repair deficiency (dMMR)
Pembrolizumab D10574 L01XC18 Keytruda PD1 PDL1 positive
Microsatellite instability-high (MSI-H) or mismatch repair deficiency (dMMR)
Blinatumomab D09325 L01XC19 Blincyto CD19 Philadelphia chromosome (BCR-ABL fusion gene) negative
Mogamulizumab D09761 L01XC25 Poteligeo CCR4 CCR4 positive
Inotuzumab ozogamicin D08933 L01XC26 Besponsa CD22 CD22 positive
Durvalumab D10808 L01XC28 Imfinzi PDL1 PDL1 positive
Avelumab D10817 L01XC31 Bavencio PDL1 PDL1 positive
Atezolizumab D10773 L01XC32 Tecentriq PDL1 PDL1 positive
HER2 negative
ESR1, PGR negative
Cemiplimab D11108 L01XC33 Libtayo PD1 PDL1 positive
Trastuzumab deruxtecan D11529 Enhertu HER2 HER2 positive 2064v1
2064v3
nt06270
Imatinib D01441 L01XE01 Gleevec BCR-ABL
FIP1L1-PDGFRA
KIT
PDGFR
Philadelphia chromosome (BCR-ABL fusion gene)
FIP1L1-PDGFRA fusion gene
KIT mutation D816V negative
PDGFR rearrangement
25v1



nt06276
Gefitinib D01977 L01XE02 Iressa EGFR EGFR exon 19 deletion or exon 21 L858R mutation 1956v2 nt06266
Erlotinib D04023 L01XE03 Tarceva EGFR EGFR exon 19 deletion or exon 21 L858R mutation 1956v2 nt06266
Dasatinib D06414 L01XE06 Sprycel BCR-ABL Philadelphia chromosome, BCR-ABL T315I mutation 25v2 nt06276
Lapatinib D04024 L01XE07 Tykerb EGFR
HER2
HER2 positive
ESR1, PGR positive
HLA-DQA1*0201 or HLA-DRB1*0701 allele carrier
2064v1 nt06270
Nilotinib D06413 L01XE08 Tasigna BCR-ABL Philadelphia chromosome (BCR-ABL fusion gene)
UGT1A1*28 allele homozygotes
25v2
54658v1
nt06276
Everolimus D02714 L01XE10
L04AA18
Afinitor
Zortress
MTOR ESR1 positive
HER2 negative
Afatinib D09733 L01XE13 Giotrif EGFR EGFR exon 19 deletion or exon 21 L858R mutation 1956v2 nt06266
Bosutinib D09728 L01XE14 Bosulif BCR-ABL Philadelphia chromosome (BCR-ABL fusion gene) 25v2 nt06276
Vemurafenib D09996 L01XE15 Zelboraf BRAF BRAF V600E mutation
NRAS mutation
673v1 nt06268
Crizotinib D09731 L01XE16 Xalkori EML4-ALK
ROS1
EML4-ALK fusion gene
ROS1 fusion gene
238v1
6098v1
nt06266
Dabrafenib D10104 L01XE23 Tafinlar BRAF BRAF V600E mutation
G6PD deficiency
673v1 nt06268
Ponatinib D09951 L01XE24 Iclusig BCR-ABL Philadelphia chromosome, BCR-ABL T315I mutation 25v2 nt06276
Trametinib D10176 L01XE25 Mekinist MEK BRAF V600E/K mutation 673v1 nt06268
Ibrutinib D10223 L01XE27 Imbruvica BTK Chromosome 17p deletion
Chromosome 11q deletion
Ceritinib D10551 L01XE28 Zykadia EML4-ALK ALK gene rearrangement 238v2 nt06266
Palbociclib D10372 L01XE33 Ibrance CDK4/6 ESR1 positive
HER2 negative
Osimertinib D10766 L01XE35 Tagrisso EGFR EGFR T790M mutation 1956v3 nt06266
Alectinib D10450 L01XE36 Alecensa EML4-ALK ALK gene rearrangement 238v2 nt06266
Cobimetinib D10615 L01XE38 Cotellic MEK BRAF V600E/K mutation 673v1 nt06268
Midostaurin D05029 L01XE39 Rydapt FLT3 (CD135) FLT3 mutation 2322v1
2322v2
Binimetinib D10604 L01XE41 Mektovi MEK BRAF V600E/K mutation 673v1 nt06268
Ribociclib D10979 L01XE42 Kisqali CDK4/6 ESR1 positive
HER2 negative
Brigatinib D10866 L01XE43 Alunbrig EML4-ALK ALK gene rearrangement 238v2 nt06266
Lorlatinib D11012 L01XE44 Lorbrena EML4-ALK ALK gene rearrangement 238v2 nt06266
Neratinib D10898 L01XE45 Nerlynx EGFR
HER2
HER4
HER2 positive 2064v1
2064v3
nt06270
Encorafenib D11053 L01XE46 Braftovi BRAF BRAF V600E/K mutation 673v1 nt06268
Dacomitinib D10514 L01XE47 Vizimpro EGFR EGFR exon 19 deletion or exon 21 L858R mutation 1956v2 nt06266
Abemaciclib D10688 L01XE50 Verzenio CDK4/6 ESR1 positive
HER2 negative
Quizartinib D09956 L01XE52 Vanflyta FLT3 (CD135) FLT3 mutation 2322v2
Larotrectinib D11138 L01XE53 Vitrakvi TRKA TRK positive
Gilteritinib D10800 L01XE54 Xospata FLT3 (CD135) FLT3 mutation 2322v1
2322v2
Entrectinib D10926 L01XE56 Rozlytrek NTRK1
ROS1
NTRK1 fusion gene
ROS1 fusion gene
4914v1
6098v1
Erdafitinib D10927 Balversa FGFR3
FGFR2
FGFR3,2 genetic alterations 2261v2
2263v2
nt06265
Omacetaxine D08956 L01XX40 Synribo CCND1 Philadelphia chromosome (BCR-ABL fusion gene) negative
Olaparib D09730 L01XX46 Lynparza PARP1 BRCA1,2 mutation
HER2 negative
Venetoclax D10679 L01XX52 Venclexta BCL2 Chromosome 17p deletion
Niraparib D10140 L01XX54 Zejula PARP1 BRCA1,2 mutation or wild type
Rucaparib D10079 L01XX55 Rubraca PARP1 BRCA1,2 mutation
Enasidenib D11044 L01XX59 Idhifa IDH2 IDH2 mutation 3418v1
Talazoparib D10733 L01XX60 Talzenna PARP1/2 BRCA1,2 mutation
HER2 negative
Ivosidenib D11090 L01XX62 Tibsovo IDH1 IDH1 mutation 3417v1
Alpelisib D11011 L01XX65 Piqray PIK3CA PIK3CA mutation
ESR1 positive
HER2 negative
5290v1 nt06270
Tamoxifen D00966 L02BA01 Nolvadex NR3A (ESR) ESR1, PGR positive
Factor V Leiden negative
Prothrombin G20210A negative

2153v1
2147v1
Fulvestrant D01161 L02BA03 Faslodex NR3A (ESR) ESR1, PGR positive
HER2 negative
Anastrozole D00960 L02BG03 Arimidex CYP19A1 (ARO) ESR1, PGR positive
Letrozole D00964 L02BG04 Femara CYP19A1 (ARO) ESR1, PGR positive
Exemestane D00963 L02BG06 Aromasin CYP19A1 (ARO) ESR1, PGR positive
Ibritumomab tiuxetan D04489 V10XX02 Zevalin CD20 CD20 positive
Tucatinib D11141 Tukysa HER2
HER3
HER2 positive 2064v1
2064v3
nt06270
Pemigatinib D11417 Pemazyre FGFR2 FGFR2 fusion gene 2263v2
Selpercatinib D11713 Retevmo RET RET fusion positive 5979v1
5979v2
nt06274
Tepotinib D11073 Tepmetko MET MET exon 14 skipping 4233v4 nt06266
Capmatinib D10891 Tabrecta MET MET exon 14 skipping 4233v4 nt06266
Sacituzumab govitecan D10985 Trodelvy TOP1
TACSTD2
HER2 negative
ESR1, PGR negative
Letrozole and ribociclib D11068 Kisqali femara ESR1, PGR positive
HER2 negative

Germline mutations in genetic disorder treatments

Drug KEGG
DRUG
ATC Product KEGG
DISEASE
Biomarker KEGG
VARIANT
KEGG
NETWORK
Carglumic acid D07130 A16AA05 Carbaglu H01032 NAGS deficiency (CPS1 activator) 162417v1 nt06010
Imiglucerase D03020 A16AB02 Cerezyme H00126 GBA deficiency (enzyme replacement) 2629v1 nt06014
Agalsidase alpha D02784 A16AB03 H00125 GLA deficiency (enzyme replacement) 2717v1 nt06014
Agalsidase beta D03228 A16AB04 Fabrazyme H00125 GLA deficiency (enzyme replacement) 2717v1 nt06014
Laronidase D04670 A16AB05 Aldurazyme H00128 IDUA deficiency (enzyme replacement) 3425v1 nt06012
Sacrosidase D05782 A16AB06 Sucraid H00115 SI deficiency (enzyme replacement) 6476v1
Alglucosidase alfa D03207 A16AB07 Lumizyme H01940 GAA deficiency (enzyme replacement) 2548v1 nt06017
Galsulfase D06565 A16AB08 Naglazyme H00131 ARSB deficiency (enzyme replacement) 411v1 nt06012
Idursulfase D04499 A16AB09 Elaprase H00129 IDS deficiency (enzyme replacement) 3423v1 nt06012
Velaglucerase alfa D09029 A16AB10 Vpriv H00126 GBA deficiency (enzyme replacement) 2629v1 nt06014
Taliglucerase alfa D09675 A16AB11 Elelyso H00126 GBA deficiency (enzyme replacement) 2629v1 nt06014
Elosulfase D10333 A16AB12 Vimizim H00123 GALNS deficiency (enzyme replacement) 2588v1 nt06012
Asfotase alfa D10595 A16AB13 Strensiq H00213 ALPL deficiency (enzyme replacement) 249v1
Sebelipase alfa D10377 A16AB14 Kanuma H00148 LIPA deficiency (enzyme replacement) 3988v1
Velmanase alfa D11024 A16AB15 Lamzede H00139 MAN2B1 deficiency (enzyme replacement) 4125v1
Cerliponase alfa D10813 A16AB17 Brineura H00149 TPP1 deficiency (enzyme replacement) 1200v1
Vestronidase alfa D11004 A16AB18 MepseVII H00132 GUSB deficiency (enzyme replacement) 2990v1 nt06012
Pegvaliase D11077 A16AB19 Palynziq H00167 PAH deficiency (substitution by PAL activity) 5053v1
Sodium phenylbutyrate D05868 A16AX03 Buphenyl H01398 ASS1, CPS1, OTC deficiency 445v1
1373v1
5009v1
Nitisinone D05177 A16AX04 Orfadin H00165 FAH deficiency (HPD inhibitor) 2184v1 nt06016
Miglustat D05032 A16AX06 Zavesca H00126 GBA deficiency (UGCG inhibitor) 2629v1 nt06014
Sapropterin D01798 A16AX07 Kuvan H00167 QDPR deficiency (cofactor replacement) 5860v1 nt06016
Eliglustat D09894 A16AX10 Cerdelga H00126 GBA deficiency (UGCG inhibitor)
CYP2D6 polymorphism
2629v1 nt06014
Migalastat D05031 A16AX14 Galafold H00125 GLA variant (migalastat amenable) 2717v2 nt06014
Avalglucosidase alfa D11744 H01940 GAA deficiency (enzyme replacement) 2548v1 nt06017
Fosdenopterin D11779 H02311 MOCS1 deficiency (cofactor replacement) 4337v1
Elapegademase D11017 L03AX21 Revcovi H02309 ADA deficiency (enzyme replacement) 100v1
Eteplirsen D09900 M09AX06 (Exondys 51) H01963 DMD mutation (exon 51 skipping amenable) 1756v1
Golodirsen D11707 Vyondys 53 H01963 DMD mutation (exon 53 skipping amenable) 1756v1
Ivacaftor D09916 R07AX02 Kalydeco H00218 CFTR mutation 1080v1
Lumacaftor and ivacaftor D10685 R07AX30 Orkambi H00218 CFTR mutation 1080v1
Tezacaftor and ivacaftor D11042 R07AX31 Symdeko H00218 CFTR mutation 1080v1
Elexacaftor, ivacaftor and tezacaftor D11700 Trikafta H00218 CFTR mutation 1080v1

Pathogen genome variants in infectious disease treatments

Drug KEGG
DRUG
ATC Product Target Biomarker
Maraviroc D06670 J05AX09 Selzentry CCR5 CCR5-tropic HIV-1 (R5 variant)

Polymorphisms and mutations affecting drug response

Drug KEGG
DRUG
ATC Biomarker KEGG
VARIANT
Omeprazole D00455
D05259
A02BC01 CYP2C19 polymorphism 1557v1
Pantoprazole D02593 A02BC02 CYP2C19 polymorphism 1557v1
Lansoprazole D00355 A02BC03 CYP2C19 polymorphism 1557v1
Rabeprazole D00724 A02BC04 CYP2C19 polymorphism 1557v1
Esomeprazole D01984
D04056
D10120
A02BC05 CYP2C19 polymorphism 1557v1
Dexlansoprazole D08903 A02BC06 CYP2C19 polymorphism 1557v1
Metoclopramide D05008 A03FA01 CYB5R deficiency
G6PD deficiency

2539v1
Palonosetron D05343 A04AA05 CYP2D6 polymorphism 1565v1
Dronabinol D00306 A04AD10 CYP2C9 polymorphism 1559v1
Sulfasalazine D00448 A07EC01 G6PD deficiency 2539v1
Glibenclamide (Glyburide) D00336 A10BB01 G6PD deficiency 2539v1
Chlorpropamide D00271 A10BB02 G6PD deficiency 2539v1
Glipizide D00335 A10BB07 G6PD deficiency 2539v1
Glimepiride D00593 A10BB12 G6PD deficiency 2539v1
Warfarin D00564 B01AA03 VKORC1 rs9923231
CYP2C9 polymorphism
PROC deficiency
PROS deficiency
79001v1
1559v1

 
Clopidogrel D00769 B01AC04 CYP2C19 polymorphism 1557v1
Prasugrel D05597 B01AC22 CYP2C19 polymorphism
CYP2C9 polymorphism
CYP3A5 polymorphism
CYP2B6 polymorphism
1557v1
1559v1
1577v1
1555v1
Ticagrelor D09017 B01AC24 CYP2C19 polymorphism 1557v1
Eltrombopag D03978 B02BX05 Factor V Leiden
ATIII deficiency
2153v1
 
Lusutrombopag D10476 B02BX07 Factor V Leiden
Prothrombin 20210A
ATIII deficiency
PROC deficiency
PROS deficiency
2153v1
2147v1


 
Avatrombopag D10307 B02BX08 Factor V Leiden
Prothrombin 20210A
ATIII deficiency
PROC deficiency
PROS deficiency
2153v1
2147v1


 
Quinidine D00642
D02272
C01BA01 CYP2D6 polymorphism 1565v1
Procainamide D08421
D00477
C01BA02 NAT polymorphism 9v1
10v1
Propafenone D00640 C01BC03 CYP2D6 polymorphism 1565v1
Isosorbide dinitrate D00516 C01DA08 CYB5R deficiency
Isosorbide mononitrate D00630 C01DA14 CYB5R deficiency
Hydralazine and isosorbide D10209 NAT polymorphism 9v1
10v1
Propranolol D00483 C07AA05 CYP2D6 polymorphism 1565v1
Metoprolol D00601
D00635
C07AB02 CYP2D6 polymorphism 1565v1
Carvedilol D00255
D03415
C07AG02 CYP2D6 polymorphism 1565v1
Rosuvastatin D01915 C10AA07 SLCO1B1 polymorphism
Mafenide D01166 D06BA03 G6PD deficiency 2539v1
Dapsone D00592 D10AX05
J04BA02
G6PD deficiency 2539v1
Flibanserin D02577 G02CX02 CYP2C9 polymorphism
CYP2C19 polymorphism
CYP2D6 polymorphism
1559v1
1557v1
1565v1
Drospirenone and ethinylestradiol D09741 G03AA12 CYP2C19 polymorphism 1557v1
Tolterodine D01148 G04BD07 CYP2D6 polymorphism 1565v1
Darifenacin D01699 G04BD10 CYP2D6 polymorphism 1565v1
Fesoterodine D08923 G04BD11 CYP2D6 polymorphism 1565v1
Elagolix D09336 H01CC03 SLCO1B1 polymorphism
Parathyroid hormone D05364 H05AA03 CASR positive
Sulfamethoxazole and trimethoprim D00285 J01EE01 G6PD deficiency 2539v1
Nalidixic acid D00183 J01MB02 G6PD deficiency 2539v1
Nitrofurantoin D00439 J01XE01 G6PD deficiency 2539v1
Voriconazole D00578 J02AC03 CYP2C19 polymorphism 1557v1
Rifampin, isoniazid, and pyrazinamide D10210 NAT polymorphism 9v1
10v1
Efavirenz D00896 J05AG03 CYP2B6 1555v1
Abacavir D00891 J05AF06 HLA-B*5701
Daclatasvir D10105 J05AP07 IL28B rs12979860 282617v1
Elbasvir and grazoprevir D10778 J05AP54 IL28B allele carrier
Dolutegravir D10113 J05AX12 UGT1A1 polymorphism 54658v1
Sofosbuvir D10366 J05AX15 IL28B rs12979860 282617v1
Dasabuvir, ombitasvir,
paritaprevir and ritonavir
D10582 J05AX66 IL28B rs12979860 282617v1
Mercaptopurine D00161 L01BB02 TPMT polymorphism 7172v1
Thioguanine D06109 L01BB03 TPMT polymorphism 7172v1
Fluorouracil D00584 L01BC02 DPYD deficiency
Capecitabine D01223 L01BC06 DPYD deficiency
Cisplatin D00275 L01XA01 TPMT polymorphism 7172v1
Lapatinib D04024 L01XE07 HLA-DQA1*0201
HLA-DRB1*0701
Nilotinib D06413 L01XE08 UGT1A1 polymorphism 54658v1
Pazopanib D05380 L01XE11 UGT1A1 polymorphism 54658v1
Irinotecan D01061 L01XX19 UGT1A1 polymorphism 54658v1
Belinostat D08870 L01XX49 UGT1A1 polymorphism 54658v1
Peginterferon alfa-2b D02748 L03AB10 IL28B rs12979860
Mycophenolic acid D00752
D05095
D05096
L04AA06 HPRT deficiency
Azathioprine D00238 L04AX01 TPMT polymorphism 7172v1
Lenalidomide D04687 L04AX04 Chromosome 5q deletion
Piroxicam D00127 M01AC01 CYP2C9 polymorphism 1559v1
Celecoxib D00567 L01XX33
M01AH01
CYP2C9 polymorphism 1559v1
Flurbiprofen D00330
D02290
M01AE09
M02AA19
R02AX01
S01BC04
CYP2C9 polymorphism 1559v1
Succinylcholine D00766 M03AB01 BCHE deficiency
Carisoprodol D00768 M03BA02 CYP2C19 polymorphism 1557v1
Lesinurad D09921 M04AB05 CYP2C9 polymorphism 1559v1
Pegloticase D09316 M04AX02 G6PD deficiency
Sevoflurane D00547 N01AB08 RYR1 positive
Prilocaine and lidocaine D02740 N01BB52
N01BB54
CYB5R deficiency
G6PD deficiency

2539v1
Tramadol D01355 N02AX02 CYP2D6 polymorphism 1565v1
Tramadol and acetaminophen D09999 N02AX52 CYP2D6 polymorphism 1565v1
Phenytoin D00512
D02103
N03AB02 HLA-B*1502
Fosphenytoin D02096 N03AB05 HLA-B*1502
Carbamazepine D00252 N03AF01 HLA-B*1502
HLA-A*3101
Oxcarbazepine D00533 N03AF02 HLA-B*1502
Valproic acid D00399
D00304
D00710
N03AG01 POLG deficiency
CPS1,OTC,NAGS / ASS1,ASL / ARG deficiency
(Urea cycle disorders)
1373v1
5009v1
162417v1
445v1
435v1
383v1
Lacosamide D07299 N03AX18 CYP2C19 polymorphism 1557v1
Brivaracetam D08879 N03AX23 CYP2C19 polymorphism 1557v1
Perphenazine D00503 N05AB03 CYP2D6 polymorphism 1565v1
Thioridazine D00798 N05AC02 CYP2D6 polymorphism 1565v1
Pimozide D00560 N05AG02 CYP2D6 polymorphism 1565v1
Clozapine D00283 N05AH02 CYP2D6 polymorphism 1565v1
Risperidone D00426 N05AX08 CYP2D6 polymorphism 1565v1
Aripiprazole D01164
D10364
N05AX12 CYP2D6 polymorphism 1565v1
Brexpiprazole D10309 N05AX13 CYP2D6 polymorphism 1565v1
Iloperidone D02666 N05AX14 CYP2D6 polymorphism 1565v1
Diazepam D00293 N05BA01 CYP2C19 polymorphism 1557v1
Clobazam D01253 N05BA09 CYP2C19 polymorphism 1557v1
Desipramine D00812 N06AA01 CYP2D6 polymorphism 1565v1
Imipramine D00815 N06AA02 CYP2D6 polymorphism 1565v1
Clomipramine D00811 N06AA04 CYP2D6 polymorphism 1565v1
Amitriptyline D00809 N06AA09 CYP2D6 polymorphism 1565v1
Trimipramine D02408 N06AA06 CYP2D6 polymorphism 1565v1
Nortriptyline D00816 N06AA10 CYP2D6 polymorphism 1565v1
Protriptyline D00484 N06AA11 CYP2D6 polymorphism 1565v1
Doxepin D00814 N06AA12 CYP2C19 polymorphism
CYP2D6 polymorphism
1557v1
1565v1
Fluoxetine D00823 N06AB03 CYP2D6 polymorphism 1565v1
Citalopram D00822 N06AB04 CYP2C19 polymorphism
CYP2D6 polymorphism
1557v1
1565v1
Paroxetine D02260
D05374
D05375
N06AB05 CYP2D6 polymorphism 1565v1
Fluvoxamine D00824 N06AB08 CYP2D6 polymorphism 1565v1
Escitalopram D02567 N06AB10 CYP2C19 polymorphism
CYP2D6 polymorphism
1557v1
1565v1
Nefazodone D00819 N06AX06 CYP2D6 polymorphism 1565v1
Venlafaxine D00821 N06AX16 CYP2D6 polymorphism 1565v1
Duloxetine D01179 N06AX21 CYP2D6 polymorphism 1565v1
Vortioxetine D10185 N06AX26 CYP2D6 polymorphism 1565v1
Chlordiazepoxide and amitriptyline D10207 N06CA01 CYP2D6 polymorphism 1565v1
Modafinil D01832 N06BA07 CYP2D6 polymorphism 1565v1
Atomoxetine D02574 N06BA09 CYP2D6 polymorphism 1565v1
Galantamine D02173 N06DA04 CYP2D6 polymorphism 1565v1
Cevimeline D00661 N07AX03 CYP2D6 polymorphism 1565v1
Lofexidine D04765 N07BC04 CYP2D6 polymorphism 1565v1
Tetrabenazine D08575 N07XX06 CYP2D6 polymorphism 1565v1
Dextromethorphan and quinidine D10208 N07XX59 CYP2D6 polymorphism 1565v1
Deutetrabenazine D10701 CYP2D6 polymorphism 1565v1
Valbenazine D10999 CYP2D6 polymorphism 1565v1
Chloroquine D02125 P01BA01 G6PD deficiency 2539v1
Primaquine D02126 P01BA03 G6PD deficiency 2539v1
Tafenoquine D10670 P01BA07 G6PD deficiency 2539v1
Quinine sulfate D02262 P01BC01 G6PD deficiency
CYP2D6 polymorphism
2539v1
1565v1
Indacaterol D09319 R03AC18 UGT1A1 polymorphism 54658v1
Arformoterol D02981 UGT1A1 polymorphism
CYP2D6 polymorphism
54658v1
1565v1
Codeine D03580 R05DA04 CYP2D6 polymorphism 1565v1
Sodium nitrite D05865 V03AB08 G6PD deficiency 2539v1
Methylene blue D02312 V03AB17 G6PD deficiency 2539v1
Succimer D00572 G6PD deficiency 2539v1
Rasburicase D05704 V03AF07 G6PD deficiency
CYB5R deficiency
2539v1

See also: Pharmacogenomic biomarkers in drug labeling

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Last updated: June 4, 2020