KEGG BRITE: KEGG Orthology (KO) - Loxodonta africana (African savanna elephant)

KEGG Orthology (KO) - Loxodonta africana (African savanna elephant)

[ Brite menu \| Download htext \| Download json \| Help ]
	Search

One-click mode

KO

 09100 Metabolism

 09120 Genetic Information Processing

 09130 Environmental Information Processing

   09131 Membrane transport

   09132 Signal transduction

     02020 Two-component system

     04010 MAPK signaling pathway [PATH:lav04010]

     04013 MAPK signaling pathway - fly

     04016 MAPK signaling pathway - plant

     04011 MAPK signaling pathway - yeast

     04012 ErbB signaling pathway [PATH:lav04012]

     04014 Ras signaling pathway [PATH:lav04014]

     04015 Rap1 signaling pathway [PATH:lav04015]

     04310 Wnt signaling pathway [PATH:lav04310]

     04330 Notch signaling pathway [PATH:lav04330]

       100671694 DLL4; delta-like protein 4
       100662144 DLL3; delta-like protein 3
       100654838 DLL1; LOW QUALITY PROTEIN: delta-like protein 1
       100658294 JAG1; LOW QUALITY PROTEIN: protein jagged-1
       100669607 MFNG; beta-1,3-N-acetylglucosaminyltransferase manic fringe
       100655946 LFNG; beta-1,3-N-acetylglucosaminyltransferase lunatic fringe
       100659212 NOTCH1; neurogenic locus notch homolog protein 1
       100665966 NOTCH2; neurogenic locus notch homolog protein 2 isoform X2
       100661550 NOTCH3; LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 3
       100656367 NOTCH4; LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 4
       100656967 RBPJ; recombining binding protein suppressor of hairless isoform X1
       100660392 RBPJL; recombining binding protein suppressor of hairless-like protein
       100660397 HES1; transcription factor HES-1
       100675106 HES5; transcription factor HES-5
       100661585 HEY2; hairy/enhancer-of-split related with YRPW motif protein 2 isoform X1
       100657428 HEY1; hairy/enhancer-of-split related with YRPW motif protein 1 isoform X2
       100660120 HEYL; LOW QUALITY PROTEIN: hairy/enhancer-of-split related with YRPW motif-like protein
       100666789 PTCRA; pre T-cell antigen receptor alpha
       100673586 DVL3; segment polarity protein dishevelled homolog DVL-3 isoform X1
       100657749 DVL2; segment polarity protein dishevelled homolog DVL-2 isoform X1
       100657649 DVL1; segment polarity protein dishevelled homolog DVL-1 isoform X1
       100667670 NUMB; protein numb homolog isoform X3
       100674666 NUMBL; LOW QUALITY PROTEIN: numb-like protein
       100665515 ITCH; E3 ubiquitin-protein ligase Itchy homolog isoform X1
       100671097 E3 ubiquitin-protein ligase DTX3L
       100674079 DTX2; probable E3 ubiquitin-protein ligase DTX2 isoform X1
       100673734 DTX4; E3 ubiquitin-protein ligase DTX4 isoform X1
       100659187 DTX1; E3 ubiquitin-protein ligase DTX1
       100661227 DTX3; probable E3 ubiquitin-protein ligase DTX3 isoform X1
       100654887 LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase DTX3L-like
       100663807 ADAM17; disintegrin and metalloproteinase domain-containing protein 17 isoform X1
       100669746 PSEN1; LOW QUALITY PROTEIN: presenilin-1
       100660389 PSEN2; presenilin-2
       100655781 PSENEN; gamma-secretase subunit PEN-2
       100668088 NCSTN; nicastrin
       100677730 APH1A; gamma-secretase subunit APH-1A
       100677356 MAML3; mastermind-like protein 3 isoform X1
       100653892 MAML1; mastermind-like protein 1 isoform X1
       100657378 MAML2; mastermind-like protein 2 isoform X1
       100661096 EP300; LOW QUALITY PROTEIN: histone acetyltransferase p300
       100663731 LOW QUALITY PROTEIN: CREB-binding protein
       100668740 KAT2A; LOW QUALITY PROTEIN: histone acetyltransferase KAT2A
       100671393 KAT2B; histone acetyltransferase KAT2B
       100657629 SNW1; SNW domain-containing protein 1
       100674095 CTBP2; C-terminal-binding protein 2 isoform X2
       100675757 CTBP1; C-terminal-binding protein 1 isoform X1
       100668873 TLE2; LOW QUALITY PROTEIN: transducin-like enhancer protein 2
       100673880 TLE3; transducin-like enhancer protein 3 isoform X7
       100656101 transducin-like enhancer protein 4 isoform X1
       100670981 TLE1; transducin-like enhancer protein 1 isoform X6
       100675328 TLE6; transducin-like enhancer protein 6
       100660810 NCOR2; LOW QUALITY PROTEIN: nuclear receptor corepressor 2
       100659401 CIR1; corepressor interacting with RBPJ 1 isoform X1
       100654888 SPEN; LOW QUALITY PROTEIN: msx2-interacting protein
       100673540 HDAC2; LOW QUALITY PROTEIN: histone deacetylase 2
       100666845 HDAC1; histone deacetylase 1 isoform X2
       100665714 ATXN1L; ataxin-1-like
       100667899 ATXN1; ataxin-1

K06051 DLL; delta
K06051 DLL; delta
K06051 DLL; delta
K06052 JAG1; jagged-1
K05948 FNG; fringe [EC:2.4.1.222]
K05948 FNG; fringe [EC:2.4.1.222]
K02599 NOTCH1; Notch 1
K20994 NOTCH2; Notch 2
K20995 NOTCH3; Notch 3
K20996 NOTCH4; Notch 4
K06053 RBPSUH; recombining binding protein suppressor of hairless
K06053 RBPSUH; recombining binding protein suppressor of hairless
K06054 HES1; hairy and enhancer of split 1
K06055 HES5; hairy and enhancer of split 5
K09091 HEY; hairy and enhancer of split related with YRPW motif
K09091 HEY; hairy and enhancer of split related with YRPW motif
K09091 HEY; hairy and enhancer of split related with YRPW motif
K06056 PTCRA; pre T-cell antigen receptor alpha
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K06057 NUMBL; numb
K06057 NUMBL; numb
K05632 ITCH; E3 ubiquitin-protein ligase Itchy [EC:2.3.2.26]
K06058 DTX; deltex [EC:2.3.2.27]
K06058 DTX; deltex [EC:2.3.2.27]
K06058 DTX; deltex [EC:2.3.2.27]
K06058 DTX; deltex [EC:2.3.2.27]
K06058 DTX; deltex [EC:2.3.2.27]
K06058 DTX; deltex [EC:2.3.2.27]
K06059 ADAM17; disintegrin and metalloproteinase domain-containing protein 17 [EC:3.4.24.86]
K04505 PSEN1; presenilin 1 [EC:3.4.23.-]
K04522 PSEN2; presenilin 2 [EC:3.4.23.-]
K06170 PSENEN; presenilin enhancer 2
K06171 NCSTN; nicastrin
K06172 APH1; gamma-secretase subunit APH-1
K06061 MAML; mastermind
K06061 MAML; mastermind
K06061 MAML; mastermind
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K06062 PCAF; histone acetyltransferase [EC:2.3.1.48]
K06062 PCAF; histone acetyltransferase [EC:2.3.1.48]
K06063 SNW1; SNW domain-containing protein 1
K04496 CTBP; C-terminal binding protein [EC:1.1.1.428]
K04496 CTBP; C-terminal binding protein [EC:1.1.1.428]
K04497 GRO; groucho
K04497 GRO; groucho
K04497 GRO; groucho
K04497 GRO; groucho
K04497 GRO; groucho
K06065 NCOR2; nuclear receptor co-repressor 2
K06066 CIR; CBF1 interacting corepressor
K25100 SPEN; Msx2-interacting protein
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K23616 ATXN1_1L; ataxin 1/1L
K23616 ATXN1_1L; ataxin 1/1L

     04340 Hedgehog signaling pathway [PATH:lav04340]

     04341 Hedgehog signaling pathway - fly

     04350 TGF-beta signaling pathway [PATH:lav04350]

     04390 Hippo signaling pathway [PATH:lav04390]

     04391 Hippo signaling pathway - fly

     04392 Hippo signaling pathway - multiple species [PATH:lav04392]

     04370 VEGF signaling pathway [PATH:lav04370]

     04371 Apelin signaling pathway [PATH:lav04371]

     04630 JAK-STAT signaling pathway [PATH:lav04630]

     04064 NF-kappa B signaling pathway [PATH:lav04064]

     04668 TNF signaling pathway [PATH:lav04668]

     04066 HIF-1 signaling pathway [PATH:lav04066]

     04068 FoxO signaling pathway [PATH:lav04068]

     04020 Calcium signaling pathway [PATH:lav04020]

     04070 Phosphatidylinositol signaling system [PATH:lav04070]

     04072 Phospholipase D signaling pathway [PATH:lav04072]

     04071 Sphingolipid signaling pathway [PATH:lav04071]

     04024 cAMP signaling pathway [PATH:lav04024]

     04022 cGMP-PKG signaling pathway [PATH:lav04022]

     04151 PI3K-Akt signaling pathway [PATH:lav04151]

     04152 AMPK signaling pathway [PATH:lav04152]

     04150 mTOR signaling pathway [PATH:lav04150]

     04075 Plant hormone signal transduction

   09133 Signaling molecules and interaction

 09140 Cellular Processes

 09150 Organismal Systems

   09151 Immune system

     04640 Hematopoietic cell lineage [PATH:lav04640]

     04610 Complement and coagulation cascades [PATH:lav04610]

     04611 Platelet activation [PATH:lav04611]

     04613 Neutrophil extracellular trap formation [PATH:lav04613]

     04620 Toll-like receptor signaling pathway [PATH:lav04620]

     04624 Toll and Imd signaling pathway

     04621 NOD-like receptor signaling pathway [PATH:lav04621]

     04622 RIG-I-like receptor signaling pathway [PATH:lav04622]

     04623 Cytosolic DNA-sensing pathway [PATH:lav04623]

     04625 C-type lectin receptor signaling pathway [PATH:lav04625]

     04650 Natural killer cell mediated cytotoxicity [PATH:lav04650]

     04612 Antigen processing and presentation [PATH:lav04612]

     04660 T cell receptor signaling pathway [PATH:lav04660]

     04658 Th1 and Th2 cell differentiation [PATH:lav04658]

       100671694 DLL4; delta-like protein 4
       100662144 DLL3; delta-like protein 3
       100654838 DLL1; LOW QUALITY PROTEIN: delta-like protein 1
       100661550 NOTCH3; LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 3
       100677356 MAML3; mastermind-like protein 3 isoform X1
       100653892 MAML1; mastermind-like protein 1 isoform X1
       100657378 MAML2; mastermind-like protein 2 isoform X1
       100656967 RBPJ; recombining binding protein suppressor of hairless isoform X1
       100660392 RBPJL; recombining binding protein suppressor of hairless-like protein
       100662194 NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1
       100654730 RELA; transcription factor p65 isoform X2
       100663285 IFNG; interferon gamma
       100665172 IFNGR1; interferon gamma receptor 1
       100667304 IFNGR2; interferon gamma receptor 2 isoform X1
       100655548 JAK1; tyrosine-protein kinase JAK1
       100676652 JAK2; tyrosine-protein kinase JAK2 isoform X1
       100668424 STAT1; signal transducer and activator of transcription 1-alpha/beta
       100665137 IL12A; interleukin-12 subunit alpha
       100657211 IL12B; interleukin-12 subunit beta
       100672726 IL12RB1; interleukin-12 receptor subunit beta-1 isoform X1
       100666176 IL12RB2; interleukin-12 receptor subunit beta-2 isoform X1
       100672245 TYK2; non-receptor tyrosine-protein kinase TYK2
       100668145 STAT4; signal transducer and activator of transcription 4 isoform X1
       100676521 TBX21; LOW QUALITY PROTEIN: T-box transcription factor TBX21
       100670732 RUNX3; LOW QUALITY PROTEIN: runt-related transcription factor 3
       100672091 HLA class II histocompatibility antigen, DO alpha chain isoform X1
       100672379 HLA class II histocompatibility antigen, DM alpha chain
       100664409 HLA class II histocompatibility antigen, DQ alpha 2 chain-like
       100665293 HLA class II histocompatibility antigen, DRB1-4 beta chain-like
       100662176 HLA class II histocompatibility antigen, DP alpha 1 chain-like isoform X4
       100668794 HLA class II histocompatibility antigen, DQ beta 2 chain-like isoform X2
       100673529 HLA class II histocompatibility antigen, DO beta chain
       100675728 DLA class II histocompatibility antigen, DR-1 beta chain-like
       100669075 LOW QUALITY PROTEIN: HLA class II histocompatibility antigen, DQ beta 1 chain-like
       100666146 HLA class II histocompatibility antigen, DR alpha chain-like
       100665860 DLA class II histocompatibility antigen, DR-1 beta chain-like
       100675445 LOW QUALITY PROTEIN: HLA class II histocompatibility antigen, DR alpha chain-like
       100667002 LOW QUALITY PROTEIN: HLA class II histocompatibility antigen, DR alpha chain-like
       100664981 LOW QUALITY PROTEIN: HLA class II histocompatibility antigen, DR alpha chain-like
       100665266 LOW QUALITY PROTEIN: mamu class II histocompatibility antigen, DR alpha chain-like
       100671834 HLA class II histocompatibility antigen, DP beta 1 chain-like
       111748122 SLA class II histocompatibility antigen, DQ haplotype C beta chain-like
       100672669 HLA class II histocompatibility antigen, DM beta chain isoform X1
       100674958 mamu class II histocompatibility antigen, DR alpha chain
       100665550 LOW QUALITY PROTEIN: HLA class II histocompatibility antigen, DR alpha chain-like
       100665834 DLA class II histocompatibility antigen, DR-1 beta chain-like
       111748125 HLA class II histocompatibility antigen, DP beta 1 chain-like
       100671798 LOW QUALITY PROTEIN: HLA class II histocompatibility antigen, DP alpha 1 chain
       100673824 HLA class II histocompatibility antigen, DQ beta 2 chain-like
       100659676 DLA class II histocompatibility antigen, DR-1 beta chain-like
       100675007 CD4; LOW QUALITY PROTEIN: T-cell surface glycoprotein CD4
       100666557 LCK; tyrosine-protein kinase Lck isoform X2
       100654724 CD3E; T-cell surface glycoprotein CD3 epsilon chain isoform X1
       100661940 CD3G; T-cell surface glycoprotein CD3 gamma chain isoform X1
       100676739 uncharacterized protein LOC100676739
       111749403 immunoglobulin gamma-1 heavy chain-like
       100656321 CD247; T-cell surface glycoprotein CD3 zeta chain
       100661471 CD3D; T-cell surface glycoprotein CD3 delta chain
       100666693 tyrosine-protein kinase ZAP-70
       100675602 LAT; linker for activation of T-cells family member 1
       100677739 PLCG1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1
       100661626 PPP3CA; serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform
       100664832 PPP3CC; serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform isoform X1
       100677352 PPP3CB; serine/threonine-protein phosphatase 2B catalytic subunit beta isoform isoform X1
       111751572 PPP3R1; calcineurin subunit B type 1
       100668807 PPP3R2; calcineurin subunit B type 2
       100655623 NFATC1; nuclear factor of activated T-cells, cytoplasmic 1 isoform X3
       100672662 NFATC2; nuclear factor of activated T-cells, cytoplasmic 2 isoform X1
       100658037 NFATC3; nuclear factor of activated T-cells, cytoplasmic 3 isoform X2
       100657357 PRKCQ; protein kinase C theta type
       100664361 CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1
       100657363 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta isoform X3
       100661492 IKBKG; LOW QUALITY PROTEIN: NF-kappa-B essential modulator
       100675651 NFKBIA; NF-kappa-B inhibitor alpha
       100657581 NFKBIB; NF-kappa-B inhibitor beta
       100660527 NFKBIE; NF-kappa-B inhibitor epsilon
       100658240 MAPK3; mitogen-activated protein kinase 3
       100665157 MAPK1; mitogen-activated protein kinase 1
       100674799 FOS; LOW QUALITY PROTEIN: proto-oncogene c-Fos
       100673331 MAPK14; mitogen-activated protein kinase 14 isoform X1
       100656926 MAPK13; mitogen-activated protein kinase 13
       100661039 MAPK12; mitogen-activated protein kinase 12 isoform X1
       100654943 MAPK9; mitogen-activated protein kinase 9 isoform X1
       100674229 MAPK8; mitogen-activated protein kinase 8 isoform X1
       100673395 MAPK10; mitogen-activated protein kinase 10 isoform X1
       100670432 JUN; transcription factor AP-1
       100656398 IL2; interleukin-2
       100655361 IL2RA; interleukin-2 receptor subunit alpha
       100669139 IL2RB; interleukin-2 receptor subunit beta isoform X1
       100664834 IL2RG; cytokine receptor common subunit gamma isoform X1
       100665896 JAK3; LOW QUALITY PROTEIN: tyrosine-protein kinase JAK3
       100672448 signal transducer and activator of transcription 5A
       100669299 STAT5B; signal transducer and activator of transcription 5B isoform X1
       100674484 IL4; interleukin-4
       100654822 IL4R; interleukin-4 receptor subunit alpha
       100675819 STAT6; signal transducer and activator of transcription 6 isoform X1
       100655161 GATA3; LOW QUALITY PROTEIN: trans-acting T-cell-specific transcription factor GATA-3
       100663565 IL5; interleukin-5
       100674770 IL13; interleukin-13
       100675973 MAF; LOW QUALITY PROTEIN: transcription factor Maf
       100658294 JAG1; LOW QUALITY PROTEIN: protein jagged-1
       100659212 NOTCH1; neurogenic locus notch homolog protein 1
       100665966 NOTCH2; neurogenic locus notch homolog protein 2 isoform X2

K06051 DLL; delta
K06051 DLL; delta
K06051 DLL; delta
K20995 NOTCH3; Notch 3
K06061 MAML; mastermind
K06061 MAML; mastermind
K06061 MAML; mastermind
K06053 RBPSUH; recombining binding protein suppressor of hairless
K06053 RBPSUH; recombining binding protein suppressor of hairless
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04687 IFNG; interferon gamma
K05132 IFNGR1; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11220 STAT1; signal transducer and activator of transcription 1
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05063 IL12RB1; interleukin 12 receptor beta-1
K05064 IL12RB2; interleukin 12 receptor beta-2
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
K11222 STAT4; signal transducer and activator of transcription 4
K10166 TBX21; T-box protein 21
K09279 RUNX3; runt-related transcription factor 3
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06454 CD4; T-cell surface glycoprotein CD4
K05856 LCK; lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2]
K06451 CD3E; T-cell surface glycoprotein CD3 epsilon chain
K06452 CD3G; T-cell surface glycoprotein CD3 gamma chain
K10785 TRBV; T-cell receptor beta chain V region
K10785 TRBV; T-cell receptor beta chain V region
K06453 CD3Z; CD3Z antigen, zeta polypeptide
K06450 CD3D; T-cell surface glycoprotein CD3 delta chain
K07360 ZAP70; tyrosine-protein kinase ZAP-70 [EC:2.7.10.2]
K07362 LAT; linker for activation of T cells family member 1
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K04446 NFATC1; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3; nuclear factor of activated T-cells, cytoplasmic 3
K18052 PRKCQ; novel protein kinase C theta type [EC:2.7.11.13]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02581 NFKBIB; NF-kappa-B inhibitor beta
K05872 NFKBIE; NF-kappa-B inhibitor epsilon
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04379 FOS; proto-oncogene protein c-fos
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K05429 IL2; interleukin 2
K05068 IL2RA; interleukin 2 receptor alpha
K05069 IL2RB; interleukin 2 receptor beta
K05070 IL2RG; interleukin 2 receptor gamma
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K05430 IL4; interleukin 4
K05071 IL4R; interleukin 4 receptor
K11225 STAT6; signal transducer and activator of transcription 6
K17895 GATA3; GATA-binding protein 3
K05428 IL5; interleukin 5
K05435 IL13; interleukin 13
K09035 CMAF; transcription factor Maf
K06052 JAG1; jagged-1
K02599 NOTCH1; Notch 1
K20994 NOTCH2; Notch 2

     04659 Th17 cell differentiation [PATH:lav04659]

     04657 IL-17 signaling pathway [PATH:lav04657]

     04662 B cell receptor signaling pathway [PATH:lav04662]

     04664 Fc epsilon RI signaling pathway [PATH:lav04664]

     04666 Fc gamma R-mediated phagocytosis [PATH:lav04666]

     04670 Leukocyte transendothelial migration [PATH:lav04670]

     04672 Intestinal immune network for IgA production [PATH:lav04672]

     04062 Chemokine signaling pathway [PATH:lav04062]

   09152 Endocrine system

   09153 Circulatory system

   09154 Digestive system

   09155 Excretory system

   09156 Nervous system

   09157 Sensory system

   09158 Development and regeneration

   09149 Aging

   09159 Environmental adaptation

 09160 Human Diseases

   09161 Cancer: overview

     05200 Pathways in cancer [PATH:lav05200]

       100672256 CASP3; caspase-3 isoform X2
       100656597 CASP9; caspase-9 isoform X3
       100657434 APPL1; DCC-interacting protein 13-alpha isoform X1
       100659456 CDH1; cadherin-1
       100670988 CTNNB1; LOW QUALITY PROTEIN: catenin beta-1
       100667386 CTNNA3; catenin alpha-3
       100672682 CTNNA1; LOW QUALITY PROTEIN: catenin alpha-1
       100661836 CTNNA2; catenin alpha-2 isoform X3
       100655765 AXIN1; axin-1
       100663921 AXIN2; axin-2
       100659017 APC; adenomatous polyposis coli protein isoform X2
       100675105 GSK3B; glycogen synthase kinase-3 beta isoform X2
       100663559 TCF7; transcription factor 7 isoform X3
       100656106 TCF7L2; transcription factor 7-like 2 isoform X22
       100658960 LEF1; lymphoid enhancer-binding factor 1 isoform X2
       100671026 BIRC5; baculoviral IAP repeat-containing protein 5
       100665874 MYC; myc proto-oncogene protein
       100669703 CCND1; G1/S-specific cyclin-D1
       100653551 WNT2B; protein Wnt-2b
       100657046 WNT2; protein Wnt-2
       100663058 WNT3; proto-oncogene Wnt-3
       100662337 WNT3A; protein Wnt-3a
       100664388 WNT4; LOW QUALITY PROTEIN: protein Wnt-4
       100664544 WNT5B; protein Wnt-5b isoform X2
       100658849 WNT5A; protein Wnt-5a isoform X1
       100675069 WNT6; protein Wnt-6
       100675463 WNT7A; protein Wnt-7a
       100660629 WNT7B; protein Wnt-7b
       100665788 WNT8B; protein Wnt-8b
       100668409 WNT8A; protein Wnt-8a
       100658979 WNT9B; protein Wnt-9b
       100662057 WNT9A; protein Wnt-9a
       100674782 WNT10A; protein Wnt-10a
       100655805 WNT10B; protein Wnt-10b
       100656630 WNT11; protein Wnt-11
       100659037 WNT16; protein Wnt-16
       100657335 FZD1; frizzled-1
       100658936 FZD7; frizzled-7
       100654997 FZD2; frizzled-2
       100666465 FZD3; frizzled-3
       100675317 FZD4; frizzled-4
       100674586 FZD5; frizzled-5
       100666499 FZD8; LOW QUALITY PROTEIN: frizzled-8
       100677440 FZD6; frizzled-6
       100660631 FZD10; frizzled-10
       100658734 LRP6; LOW QUALITY PROTEIN: low-density lipoprotein receptor-related protein 6
       100666209 LRP5; LOW QUALITY PROTEIN: low-density lipoprotein receptor-related protein 5
       100673586 DVL3; segment polarity protein dishevelled homolog DVL-3 isoform X1
       100657749 DVL2; segment polarity protein dishevelled homolog DVL-2 isoform X1
       100657649 DVL1; segment polarity protein dishevelled homolog DVL-1 isoform X1
       100669466 FRAT1; proto-oncogene FRAT1
       100669183 FRAT2; GSK-3-binding protein FRAT2
       100666651 F2; prothrombin
       100670141 AGT; LOW QUALITY PROTEIN: angiotensinogen
       100668995 F2R; proteinase-activated receptor 1
       100653569 F2RL3; proteinase-activated receptor 4
       100668056 LPAR1; lysophosphatidic acid receptor 1 isoform X1
       100674529 LPAR2; lysophosphatidic acid receptor 2
       100655832 LPAR3; lysophosphatidic acid receptor 3
       100656506 LPAR4; lysophosphatidic acid receptor 4
       100674432 LPAR5; lysophosphatidic acid receptor 5
       100669291 LPAR6; lysophosphatidic acid receptor 6
       100659079 AGTR1; type-1 angiotensin II receptor
       100676444 GNA12; guanine nucleotide-binding protein subunit alpha-12
       100664965 GNA13; guanine nucleotide-binding protein subunit alpha-13
       100661002 ARHGEF12; rho guanine nucleotide exchange factor 12 isoform X1
       100673301 ARHGEF11; rho guanine nucleotide exchange factor 11 isoform X1
       100674589 ARHGEF1; rho guanine nucleotide exchange factor 1 isoform X2
       100670811 PLEKHG5; pleckstrin homology domain-containing family G member 5 isoform X1
       100677447 RHOA; transforming protein RhoA
       100657418 ROCK1; rho-associated protein kinase 1 isoform X1
       100658857 ROCK2; rho-associated protein kinase 2 isoform X1
       100670325 CXCL12; stromal cell-derived factor 1
       100660744 CXCR4; C-X-C chemokine receptor type 4
       100666344 GNAI1; guanine nucleotide-binding protein G(i) subunit alpha-1
       100670234 GNAI2; guanine nucleotide-binding protein G(i) subunit alpha-2
       100667957 GNAI3; LOW QUALITY PROTEIN: guanine nucleotide-binding protein G(k) subunit alpha
       100675204 PTGER1; LOW QUALITY PROTEIN: prostaglandin E2 receptor EP1 subtype
       100675931 PTGER2; LOW QUALITY PROTEIN: prostaglandin E2 receptor EP2 subtype
       100675292 PTGER3; prostaglandin E2 receptor EP3 subtype
       100658841 PTGER4; prostaglandin E2 receptor EP4 subtype
       100655206 guanine nucleotide-binding protein G(s) subunit alpha isoform X1
       100669226 neuroendocrine secretory protein 55-like
       100671072 ADCY1; adenylate cyclase type 1
       100673570 ADCY2; LOW QUALITY PROTEIN: adenylate cyclase type 2
       100674724 ADCY3; adenylate cyclase type 3
       100675525 ADCY4; adenylate cyclase type 4
       100670244 ADCY5; LOW QUALITY PROTEIN: adenylate cyclase type 5
       100653532 ADCY6; adenylate cyclase type 6 isoform X1
       100653771 ADCY7; adenylate cyclase type 7 isoform X1
       100661616 ADCY8; adenylate cyclase type 8
       100663448 ADCY9; LOW QUALITY PROTEIN: adenylate cyclase type 9
       100656966 PRKACB; cAMP-dependent protein kinase catalytic subunit beta isoform X1
       100674245 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha
       100673391 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
       100677127 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
       100674807 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
       100669106 GNB4; LOW QUALITY PROTEIN: guanine nucleotide-binding protein subunit beta-4
       100674665 GNB5; guanine nucleotide-binding protein subunit beta-5 isoform X1
       100668996 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 isoform X2
       100676083 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
       100664179 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
       100656403 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
       100655407 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
       100662559 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
       111749727 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
       111751488 GNG14; LOW QUALITY PROTEIN: putative guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-14
       111750996 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
       100675882 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
       111749728 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
       111751775 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
       100664111 COL4A3; collagen alpha-3(IV) chain
       100664398 COL4A4; collagen alpha-4(IV) chain
       100677472 COL4A1; collagen alpha-1(IV) chain
       100667607 COL4A5; collagen alpha-5(IV) chain
       100667893 collagen alpha-6(IV) chain
       100677754 COL4A2; LOW QUALITY PROTEIN: collagen alpha-2(IV) chain
       100672596 LAMA1; laminin subunit alpha-1
       100677404 LAMA2; laminin subunit alpha-2
       104845537 LAMA3; laminin subunit alpha-3
       100676944 LAMA5; LOW QUALITY PROTEIN: laminin subunit alpha-5
       111749628 laminin subunit alpha-3-like
       100662531 LAMA4; LOW QUALITY PROTEIN: laminin subunit alpha-4
       100675837 LAMB1; laminin subunit beta-1 isoform X1
       100655070 LAMB2; laminin subunit beta-2
       100666736 LAMB3; LOW QUALITY PROTEIN: laminin subunit beta-3
       100658659 LAMB4; LOW QUALITY PROTEIN: laminin subunit beta-4
       100671561 LAMC1; laminin subunit gamma-1
       100661346 LAMC2; laminin subunit gamma-2
       100670126 LAMC3; LOW QUALITY PROTEIN: laminin subunit gamma-3
       100667853 FN1; fibronectin isoform X8
       100674705 ITGA2; integrin alpha-2
       100654429 ITGA2B; LOW QUALITY PROTEIN: integrin alpha-IIb
       100671578 ITGA3; LOW QUALITY PROTEIN: integrin alpha-3
       100661035 ITGA6; integrin alpha-6 isoform X1
       100671252 ITGAV; integrin alpha-V isoform X1
       100664978 ITGB1; integrin beta-1 isoform X1
       100668436 PTK2; LOW QUALITY PROTEIN: focal adhesion kinase 1
       100657948 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
       100658340 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1
       100666266 PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
       100653731 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1
       100665045 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
       100675496 PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma
       100660561 PTEN; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X1
       100662288 NKX3-1; homeobox protein Nkx-3.1
       100663184 AKT2; RAC-beta serine/threonine-protein kinase isoform X1
       100657536 AKT3; RAC-gamma serine/threonine-protein kinase isoform X2
       100660187 AKT1; RAC-alpha serine/threonine-protein kinase
       100664361 CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1
       100657363 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta isoform X3
       100661492 IKBKG; LOW QUALITY PROTEIN: NF-kappa-B essential modulator
       100675651 NFKBIA; NF-kappa-B inhibitor alpha
       100662194 NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1
       100657917 NFKB2; nuclear factor NF-kappa-B p100 subunit isoform X2
       100654730 RELA; transcription factor p65 isoform X2
       100666359 PTGS2; prostaglandin G/H synthase 2
       100676634 NOS2; LOW QUALITY PROTEIN: nitric oxide synthase, inducible
       100675268 BCL2; apoptosis regulator Bcl-2
       100659163 baculoviral IAP repeat-containing protein 3
       100659446 baculoviral IAP repeat-containing protein 2 isoform X1
       100657657 XIAP; E3 ubiquitin-protein ligase XIAP
       100655646 BCL2L1; bcl-2-like protein 1 isoform X1
       100656766 TRAF1; TNF receptor-associated factor 1 isoform X1
       100670400 TRAF2; TNF receptor-associated factor 2 isoform X2
       100668716 TRAF3; TNF receptor-associated factor 3
       100660891 TRAF4; TNF receptor-associated factor 4
       100663885 TRAF5; TNF receptor-associated factor 5
       100671471 TRAF6; TNF receptor-associated factor 6
       100660112 MTOR; LOW QUALITY PROTEIN: serine/threonine-protein kinase mTOR
       100653946 RPS6KB1; ribosomal protein S6 kinase beta-1 isoform X1
       100671034 RPS6KB2; ribosomal protein S6 kinase beta-2 isoform X1
       100668387 BAD; bcl2-associated agonist of cell death
       100655740 FOXO1; forkhead box protein O1
       100669448 MDM2; E3 ubiquitin-protein ligase Mdm2 isoform X2
       100663725 TP53; cellular tumor antigen p53 isoform X1
       100674125 CDKN1B; cyclin-dependent kinase inhibitor 1B
       100671706 CDKN1A; cyclin-dependent kinase inhibitor 1
       100670748 BCR; breakpoint cluster region protein
       100677152 ABL1; tyrosine-protein kinase ABL1 isoform X1
       100659273 CRK; adapter molecule crk isoform X1
       100662046 CRKL; crk-like protein
       100658892 CBL; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase CBL
       100672448 signal transducer and activator of transcription 5A
       100669299 STAT5B; signal transducer and activator of transcription 5B isoform X1
       100677514 PIM1; LOW QUALITY PROTEIN: serine/threonine-protein kinase pim-1
       100664013 PIM2; serine/threonine-protein kinase pim-2
       100655555 KNG1; kininogen-1
       100672459 EDN1; endothelin-1 isoform X1
       100674513 BDKRB1; B1 bradykinin receptor
       100666730 BDKRB2; B2 bradykinin receptor
       100654723 EDNRA; endothelin-1 receptor
       100654118 EDNRB; endothelin receptor type B isoform X1
       100656672 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha isoform X1
       100675896 guanine nucleotide-binding protein subunit alpha-11
       100670617 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X3
       100672435 PLCB1; LOW QUALITY PROTEIN: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1
       100668575 PLCB2; LOW QUALITY PROTEIN: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2
       100663829 PLCB3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 isoform X1
       100665537 PRKCA; protein kinase C alpha type isoform X1
       100672078 PRKCB; LOW QUALITY PROTEIN: protein kinase C beta type
       100671733 PRKCG; LOW QUALITY PROTEIN: protein kinase C gamma type
       100656398 IL2; interleukin-2
       111750521 interleukin-3-like
       100674484 IL4; interleukin-4
       100663565 IL5; interleukin-5
       100660846 IL6; interleukin-6
       100658284 IL7; interleukin-7
       100665137 IL12A; interleukin-12 subunit alpha
       100657211 IL12B; interleukin-12 subunit beta
       100674770 IL13; interleukin-13
       100657564 IL15; interleukin-15
       100656085 IL23A; interleukin-23 subunit alpha
       100665583 interferon alpha-5-like
       100659984 interferon alpha-5-like
       100660270 interferon alpha-5-like
       100661986 interferon alpha-5-like
       100662831 interferon alpha-5-like
       100663685 interferon alpha-6-like
       100660554 interferon alpha-5-like
       100661135 interferon alpha-5-like
       100663285 IFNG; interferon gamma
       100655361 IL2RA; interleukin-2 receptor subunit alpha
       100669139 IL2RB; interleukin-2 receptor subunit beta isoform X1
       100664834 IL2RG; cytokine receptor common subunit gamma isoform X1
       104847204 IL3RA; interleukin-3 receptor subunit alpha isoform X1
       100654822 IL4R; interleukin-4 receptor subunit alpha
       100671503 cytokine receptor common subunit beta-like
       100670281 cytokine receptor common subunit beta
       100662380 IL5RA; interleukin-5 receptor subunit alpha
       100664198 IL6R; interleukin-6 receptor subunit alpha
       100669556 IL6ST; interleukin-6 receptor subunit beta isoform X2
       100671266 IL7R; interleukin-7 receptor subunit alpha isoform X1
       100672726 IL12RB1; interleukin-12 receptor subunit beta-1 isoform X1
       100666176 IL12RB2; interleukin-12 receptor subunit beta-2 isoform X1
       100661365 IL13RA1; interleukin-13 receptor subunit alpha-1 isoform X1
       100655923 IL15RA; interleukin-15 receptor subunit alpha
       100654129 IL23R; interleukin-23 receptor
       100666267 EPOR; LOW QUALITY PROTEIN: erythropoietin receptor
       100667586 IFNAR1; interferon alpha/beta receptor 1
       100672898 IFNAR2; interferon alpha/beta receptor 2 isoform X2
       100665172 IFNGR1; interferon gamma receptor 1
       100667304 IFNGR2; interferon gamma receptor 2 isoform X1
       104846437 EML4; echinoderm microtubule-associated protein-like 4 isoform X1
       100661350 ALK; ALK tyrosine kinase receptor
       100667149 RASGRP1; RAS guanyl-releasing protein 1 isoform X1
       100661291 RASGRP2; RAS guanyl-releasing protein 2
       100664201 RASGRP3; ras guanyl-releasing protein 3 isoform X1
       100654736 RASGRP4; RAS guanyl-releasing protein 4 isoform X1
       100655548 JAK1; tyrosine-protein kinase JAK1
       100676652 JAK2; tyrosine-protein kinase JAK2 isoform X1
       100665896 JAK3; LOW QUALITY PROTEIN: tyrosine-protein kinase JAK3
       100669583 STAT3; signal transducer and activator of transcription 3 isoform X2
       100668424 STAT1; signal transducer and activator of transcription 1-alpha/beta
       100656374 STAT2; signal transducer and activator of transcription 2
       100668145 STAT4; signal transducer and activator of transcription 4 isoform X1
       100675819 STAT6; signal transducer and activator of transcription 6 isoform X1
       100661392 VEGFA; vascular endothelial growth factor A
       100668949 VEGFB; vascular endothelial growth factor B isoform X1
       100674895 PGF; placenta growth factor isoform X2
       100657845 VEGFC; vascular endothelial growth factor C
       100665819 VEGFD; vascular endothelial growth factor D
       100665332 TGFA; protransforming growth factor alpha
       100670137 EGF; LOW QUALITY PROTEIN: pro-epidermal growth factor
       100659125 EGFR; epidermal growth factor receptor isoform X1
       100662583 ERBB2; receptor tyrosine-protein kinase erbB-2 isoform X2
       100663544 PDGFB; platelet-derived growth factor subunit B isoform X2
       100670735 PDGFRA; platelet-derived growth factor receptor alpha isoform X1
       100671240 PDGFRB; platelet-derived growth factor receptor beta isoform X1
       100664710 IGF1; insulin-like growth factor I isoform X1
       100664990 IGF2; insulin-like growth factor II
       100655087 IGF1R; insulin-like growth factor 1 receptor
       100654759 KITLG; kit ligand isoform X1
       100655943 KIT; mast/stem cell growth factor receptor Kit isoform X2
       100669548 FLT3LG; fms-related tyrosine kinase 3 ligand isoform X3
       100668366 FLT3; receptor-type tyrosine-protein kinase FLT3 isoform X1
       100665493 HGF; hepatocyte growth factor
       100656285 MET; hepatocyte growth factor receptor isoform X1
       100663763 FGF1; fibroblast growth factor 1
       100657533 FGF2; fibroblast growth factor 2
       100663120 FGF10; fibroblast growth factor 10
       100668915 FGF6; fibroblast growth factor 6
       100658495 FGF16; LOW QUALITY PROTEIN: fibroblast growth factor 16
       100675766 FGF17; fibroblast growth factor 17 isoform X1
       100671479 FGF9; fibroblast growth factor 9
       100672847 FGF7; fibroblast growth factor 7
       100668860 FGF4; fibroblast growth factor 4
       100662939 FGF8; fibroblast growth factor 8
       100656834 FGF18; LOW QUALITY PROTEIN: fibroblast growth factor 18
       100656129 FGF5; fibroblast growth factor 5
       100669156 FGF22; LOW QUALITY PROTEIN: fibroblast growth factor 22
       100656791 FGF20; fibroblast growth factor 20
       100661893 FGF21; LOW QUALITY PROTEIN: fibroblast growth factor 21
       100668635 FGF23; fibroblast growth factor 23
       100662289 FGFR1; fibroblast growth factor receptor 1 isoform X3
       100664128 fibroblast growth factor receptor 2 isoform X1
       100674054 FGFR3; fibroblast growth factor receptor 3 isoform X1
       100672193 FGFR4; fibroblast growth factor receptor 4 isoform X1
       100655474 GRB2; growth factor receptor-bound protein 2
       100657379 SOS1; LOW QUALITY PROTEIN: son of sevenless homolog 1
       100656200 SOS2; son of sevenless homolog 2 isoform X1
       100661512 KRAS; GTPase KRas isoform X2
       100659051 NRAS; GTPase NRas
       100671404 ARAF; serine/threonine-protein kinase A-Raf isoform X3
       100664119 BRAF; serine/threonine-protein kinase B-raf
       100655727 RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X1
       100667623 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1
       100657587 MAP2K2; dual specificity mitogen-activated protein kinase kinase 2
       100658240 MAPK3; mitogen-activated protein kinase 3
       100665157 MAPK1; mitogen-activated protein kinase 1
       100670432 JUN; transcription factor AP-1
       100674799 FOS; LOW QUALITY PROTEIN: proto-oncogene c-Fos
       100656331 ETS1; protein C-ets-1
       100656422 MMP1; interstitial collagenase
       100659450 MMP2; 72 kDa type IV collagenase
       100664260 MMP9; LOW QUALITY PROTEIN: matrix metalloproteinase-9
       100664099 CXCL8; interleukin-8
       104847103 CDK4; cyclin-dependent kinase 4
       100664075 RPS6KA5; ribosomal protein S6 kinase alpha-5 isoform X1
       100672176 RET; LOW QUALITY PROTEIN: proto-oncogene tyrosine-protein kinase receptor Ret
       100667956 CCDC6; coiled-coil domain-containing protein 6
       100672028 NCOA4; nuclear receptor coactivator 4 isoform X1
       100668650 NTRK1; LOW QUALITY PROTEIN: high affinity nerve growth factor receptor
       100674827 TPM3; tropomyosin alpha-3 chain isoform X1
       100667592 TPR; nucleoprotein TPR isoform X2
       100674755 TFG; protein TFG isoform X1
       100668441 RASSF1; ras association domain-containing protein 1 isoform X1
       100664175 RASSF5; LOW QUALITY PROTEIN: ras association domain-containing protein 5
       100659146 STK4; serine/threonine-protein kinase 4 isoform X1
       100669366 DAPK1; death-associated protein kinase 1 isoform X2
       100670001 DAPK3; death-associated protein kinase 3 isoform X2
       100669221 DAPK2; death-associated protein kinase 2 isoform X1
       100677739 PLCG1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1
       100658990 PLCG2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
       100670835 ELK1; ETS domain-containing protein Elk-1 isoform X1
       100663507 CALM1; calmodulin-1
       100664679 CALM2; calmodulin-2
       100657612 calmodulin
       100669885 CALML4; calmodulin-like protein 4 isoform X1
       100658962 CALML3; calmodulin-like protein 3
       100658208 calmodulin
       104846071 CAMK2A; calcium/calmodulin-dependent protein kinase type II subunit alpha
       100653927 CAMK2G; calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X1
       100663321 CAMK2D; calcium/calmodulin-dependent protein kinase type II subunit delta isoform X2
       100658516 CAMK2B; calcium/calmodulin-dependent protein kinase type II subunit beta
       100659236 RALGDS; ral guanine nucleotide dissociation stimulator isoform X1
       100674091 LOW QUALITY PROTEIN: ral guanine nucleotide dissociation stimulator-like
       100662460 RALA; ras-related protein Ral-A
       100669974 RALB; ras-related protein Ral-B
       100674030 RALBP1; ralA-binding protein 1
       100664103 CDC42; cell division control protein 42 homolog
       100664204 RAC1; ras-related C3 botulinum toxin substrate 1
       100670080 RAC2; ras-related C3 botulinum toxin substrate 2
       100660595 PLD1; phospholipase D1 isoform X2
       100658318 PLD2; LOW QUALITY PROTEIN: phospholipase D2
       100654943 MAPK9; mitogen-activated protein kinase 9 isoform X1
       100674229 MAPK8; mitogen-activated protein kinase 8 isoform X1
       100673395 MAPK10; mitogen-activated protein kinase 10 isoform X1
       100674361 PAX8; paired box protein Pax-8
       100654408 PPARG; peroxisome proliferator-activated receptor gamma isoform X1
       100674208 retinoic acid receptor RXR-alpha-like
       100662699 RXRB; retinoic acid receptor RXR-beta isoform X2
       100653765 RXRG; retinoic acid receptor RXR-gamma
       100675215 RARB; retinoic acid receptor beta
       100677316 ESR1; estrogen receptor
       100677158 ESR2; estrogen receptor beta
       100673959 NCOA1; nuclear receptor coactivator 1 isoform X3
       100668174 NCOA3; nuclear receptor coactivator 3 isoform X1
       100662543 SP1; transcription factor Sp1
       100666968 PPARD; peroxisome proliferator-activated receptor delta isoform X1
       100666092 JUP; junction plakoglobin
       100662039 ZBTB16; zinc finger and BTB domain-containing protein 16
       100666758 RARA; retinoic acid receptor alpha isoform X1
       100667107 CCNA1; cyclin-A1
       100654979 CCNA2; cyclin-A2
       100663907 PML; protein PML isoform X2
       100665882 RUNX1; runt-related transcription factor 1 isoform X1
       100665783 RUNX1T1; protein CBFA2T1 isoform X2
       100673678 SPI1; transcription factor PU.1 isoform X2
       100664106 CEBPA; CCAAT/enhancer-binding protein alpha
       111749385 granulocyte-macrophage colony-stimulating factor receptor subunit alpha-like
       100664139 CSF2RA; granulocyte-macrophage colony-stimulating factor receptor subunit alpha isoform X1
       100665706 CSF3R; LOW QUALITY PROTEIN: granulocyte colony-stimulating factor receptor
       100670956 CSF1R; macrophage colony-stimulating factor 1 receptor isoform X1
       104845647 cyclin-dependent kinase inhibitor 2A-like
       100664468 E2F1; LOW QUALITY PROTEIN: transcription factor E2F1
       100665816 E2F2; transcription factor E2F2 isoform X1
       100656140 E2F3; transcription factor E2F3 isoform X1
       100656577 MAX; protein max isoform X2
       100654604 ZBTB17; zinc finger and BTB domain-containing protein 17 isoform X1
       100664726 CDKN2B; cyclin-dependent kinase 4 inhibitor B
       100655429 CDK6; cyclin-dependent kinase 6 isoform X1
       100668070 CCND2; G1/S-specific cyclin-D2
       100668683 CCND3; G1/S-specific cyclin-D3 isoform X1
       100654046 CKS1B; cyclin-dependent kinases regulatory subunit 1
       100657682 CKS2; cyclin-dependent kinases regulatory subunit 2
       100663845 SKP1; S-phase kinase-associated protein 1
       100664600 CUL1; cullin-1
       100657479 RBX1; E3 ubiquitin-protein ligase RBX1
       100676976 SKP2; S-phase kinase-associated protein 2 isoform X1
       100668134 CDK2; cyclin-dependent kinase 2 isoform X2
       100668342 CCNE2; G1/S-specific cyclin-E2 isoform X1
       100659451 CCNE1; G1/S-specific cyclin-E1 isoform X1
       100673196 RB1; retinoblastoma-associated protein
       100658253 GADD45G; growth arrest and DNA damage-inducible protein GADD45 gamma
       100655692 GADD45B; growth arrest and DNA damage-inducible protein GADD45 beta isoform X2
       100653562 GADD45A; growth arrest and DNA damage-inducible protein GADD45 alpha
       100673560 BAX; apoptosis regulator BAX
       100669799 BAK1; bcl-2 homologous antagonist/killer
       100665802 DDB2; DNA damage-binding protein 2 isoform X1
       100662275 POLK; DNA polymerase kappa isoform X2
       100676312 TERT; telomerase reverse transcriptase
       100668533 MITF; microphthalmia-associated transcription factor isoform X1
       100667634 TGFB1; transforming growth factor beta-1
       100656534 TGFB2; transforming growth factor beta-2 isoform X2
       100653832 TGFB3; transforming growth factor beta-3 isoform X1
       100656286 TGFBR1; TGF-beta receptor type-1 isoform X1
       100671392 TGFBR2; TGF-beta receptor type-2 isoform X2
       100663495 SMAD2; mothers against decapentaplegic homolog 2 isoform X1
       100659509 SMAD4; mothers against decapentaplegic homolog 4
       100664202 MECOM; MDS1 and EVI1 complex locus protein EVI1 isoform X7
       100674095 CTBP2; C-terminal-binding protein 2 isoform X2
       100675757 CTBP1; C-terminal-binding protein 1 isoform X1
       100673540 HDAC2; LOW QUALITY PROTEIN: histone deacetylase 2
       100666845 HDAC1; histone deacetylase 1 isoform X2
       100669404 MLH1; DNA mismatch repair protein Mlh1 isoform X1
       100653677 MSH2; DNA mismatch repair protein Msh2
       100674995 MSH3; DNA mismatch repair protein Msh3 isoform X2
       100677382 MSH6; DNA mismatch repair protein Msh6
       100669658 BRCA2; LOW QUALITY PROTEIN: breast cancer type 2 susceptibility protein
       100662321 RAD51; DNA repair protein RAD51 homolog 1
       100662586 FASLG; tumor necrosis factor ligand superfamily member 6
       100657715 FAS; tumor necrosis factor receptor superfamily member 6 isoform X1
       100662633 FADD; FAS-associated death domain protein
       100663575 caspase-8
       100660542 CASP8; caspase-8 isoform X1
       100662196 BID; BH3-interacting domain death agonist
       100677531 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
       100671262 BBC3; LOW QUALITY PROTEIN: bcl-2-binding component 3
       100659585 BCL2L11; bcl-2-like protein 11 isoform X2
       100654286 cytochrome c, testis-specific
       100657132 cytochrome c
       100665091 APAF1; apoptotic protease-activating factor 1 isoform X2
       100670890 CASP7; caspase-7 isoform X3
       100662208 KEAP1; kelch-like ECH-associated protein 1
       100655138 NFE2L2; nuclear factor erythroid 2-related factor 2 isoform X1
       100673521 HMOX1; heme oxygenase 1 isoform X2
       100668568 NQO1; NAD(P)H dehydrogenase [quinone] 1 isoform X1
       100672857 GSTA4; glutathione S-transferase A4 isoform X1
       100674860 glutathione S-transferase-like
       100673430 glutathione S-transferase A2
       100670476 glutathione S-transferase alpha-4-like
       100670760 glutathione S-transferase A1
       100675090 glutathione S-transferase omega-1
       100654951 MGST1; microsomal glutathione S-transferase 1
       100668813 glutathione S-transferase Mu 4-like isoform X1
       100669275 glutathione S-transferase Mu 1-like isoform X2
       100670040 glutathione S-transferase Mu 1 isoform X1
       100654410 MGST2; microsomal glutathione S-transferase 2
       100654331 MGST3; microsomal glutathione S-transferase 3
       100677494 glutathione S-transferase theta-1-like isoform X2
       100666638 glutathione S-transferase Mu 1-like
       100667211 GSTM3; glutathione S-transferase Mu 3
       100666921 uncharacterized protein LOC100666921
       100666354 glutathione S-transferase Mu 1-like
       100659524 glutathione S-transferase omega-2
       100675794 glutathione S-transferase theta-4
       100669606 GSTP1; glutathione S-transferase P isoform X2
       100666991 TXNRD1; thioredoxin reductase 1, cytoplasmic
       100670423 TXNRD3; thioredoxin reductase 3
       100672080 TXNRD2; thioredoxin reductase 2, mitochondrial
       111750613 VHL; LOW QUALITY PROTEIN: von Hippel-Lindau disease tumor suppressor
       100655998 ELOC; elongin-C
       100658327 ELOB; elongin-B isoform X2
       100662056 CUL2; cullin-2 isoform X1
       100674039 EGLN3; egl nine homolog 3
       100672145 EGLN1; egl nine homolog 1
       100675805 EGLN2; LOW QUALITY PROTEIN: egl nine homolog 2
       100667785 FH; fumarate hydratase, mitochondrial isoform X1
       100659617 HIF1A; hypoxia-inducible factor 1-alpha
       100655103 EPAS1; endothelial PAS domain-containing protein 1 isoform X1
       100673667 ARNT; aryl hydrocarbon receptor nuclear translocator isoform X6
       100677652 ARNT2; aryl hydrocarbon receptor nuclear translocator 2
       100661096 EP300; LOW QUALITY PROTEIN: histone acetyltransferase p300
       100663731 LOW QUALITY PROTEIN: CREB-binding protein
       100677089 SLC2A1; solute carrier family 2, facilitated glucose transporter member 1
       100658294 JAG1; LOW QUALITY PROTEIN: protein jagged-1
       100671694 DLL4; delta-like protein 4
       100662144 DLL3; delta-like protein 3
       100654838 DLL1; LOW QUALITY PROTEIN: delta-like protein 1
       100659212 NOTCH1; neurogenic locus notch homolog protein 1
       100665966 NOTCH2; neurogenic locus notch homolog protein 2 isoform X2
       100661550 NOTCH3; LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 3
       100656367 NOTCH4; LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 4
       100660397 HES1; transcription factor HES-1
       100675106 HES5; transcription factor HES-5
       100661585 HEY2; hairy/enhancer-of-split related with YRPW motif protein 2 isoform X1
       100657428 HEY1; hairy/enhancer-of-split related with YRPW motif protein 1 isoform X2
       100660120 HEYL; LOW QUALITY PROTEIN: hairy/enhancer-of-split related with YRPW motif-like protein
       100677038 FLT4; LOW QUALITY PROTEIN: vascular endothelial growth factor receptor 3
       100669796 SHH; LOW QUALITY PROTEIN: sonic hedgehog protein
       100676123 PTCH1; protein patched homolog 1
       100668802 SMO; smoothened homolog
       100663622 kinesin-like protein KIF7
       104846247 kinesin-like protein KIF7
       100656489 SUFU; suppressor of fused homolog isoform X2
       100653709 GLI1; zinc finger protein GLI1
       100662027 GLI2; LOW QUALITY PROTEIN: zinc finger protein GLI2
       100657131 GLI3; transcriptional activator GLI3 isoform X1
       100654878 BMP2; bone morphogenetic protein 2
       100654115 BMP4; bone morphogenetic protein 4 isoform X1
       100656714 HHIP; hedgehog-interacting protein
       100671301 PTCH2; LOW QUALITY PROTEIN: protein patched homolog 2
       100667886 AR; androgen receptor isoform X1
       100656361 HSP90AB1; heat shock protein HSP 90-beta
       100676217 HSP90AA1; LOW QUALITY PROTEIN: heat shock protein HSP 90-alpha
       100670864 HSP90B1; endoplasmin

K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K08733 APPL1; DCC-interacting protein 13 alpha
K05689 CDH1; cadherin 1, type 1, E-cadherin
K02105 CTNNB1; catenin beta 1
K05691 CTNNA; catenin alpha
K05691 CTNNA; catenin alpha
K05691 CTNNA; catenin alpha
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02085 APC; adenomatosis polyposis coli protein
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02620 TCF7; transcription factor 7
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K08731 BIRC5; baculoviral IAP repeat-containing protein 5
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; G1/S-specific cyclin-D1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7; frizzled 1/7
K02432 FZD1_7; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4; frizzled 4
K02375 FZD5_8; frizzled 5/8
K02375 FZD5_8; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10; frizzled 9/10
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K03069 FRAT1; frequently rearranged in advanced T-cell lymphomas 1
K03096 FRAT2; frequently rearranged in advanced T-cell lymphomas 2
K01313 F2; coagulation factor II (thrombin) [EC:3.4.21.5]
K09821 AGT; angiotensinogen
K03914 F2R; coagulation factor II (thrombin) receptor
K04236 F2RL3; coagulation factor II (thrombin) receptor-like 3
K04289 LPAR1; lysophosphatidic acid receptor 1
K04291 LPAR2; lysophosphatidic acid receptor 2
K04294 LPAR3; lysophosphatidic acid receptor 3
K04275 LPAR4; lysophosphatidic acid receptor 4
K08390 LPAR5; lysophosphatidic acid receptor 5
K04273 LPAR6; lysophosphatidic acid receptor 6
K04166 AGTR1; angiotensin II receptor type 1
K04346 GNA12; guanine nucleotide-binding protein subunit alpha-12
K04639 GNA13; guanine nucleotide-binding protein subunit alpha-13
K07532 ARHGEF12; Rho guanine nucleotide exchange factor 12
K12331 ARHGEF11; Rho guanine nucleotide exchange factor 11
K12330 ARHGEF1; Rho guanine nucleotide exchange factor 1
K19464 PLEKHG5; pleckstrin homology domain-containing family G member 5
K04513 RHOA; Ras homolog gene family, member A
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K10031 CXCL12; C-X-C motif chemokine 12
K04189 CXCR4; C-X-C chemokine receptor type 4
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04258 PTGER1; prostaglandin E receptor 1
K04259 PTGER2; prostaglandin E receptor 2
K04260 PTGER3; prostaglandin E receptor 3
K04261 PTGER4; prostaglandin E receptor 4
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K05637 LAMA1_2; laminin, alpha 1/2
K05637 LAMA1_2; laminin, alpha 1/2
K06240 LAMA3_5; laminin, alpha 3/5
K06240 LAMA3_5; laminin, alpha 3/5
K06240 LAMA3_5; laminin, alpha 3/5
K06241 LAMA4; laminin, alpha 4
K05636 LAMB1; laminin, beta 1
K06243 LAMB2; laminin, beta 2
K06244 LAMB3; laminin, beta 3
K06245 LAMB4; laminin, beta 4
K05635 LAMC1; laminin, gamma 1
K06246 LAMC2; laminin, gamma 2
K06247 LAMC3; laminin, gamma 3
K05717 FN1; fibronectin 1
K06481 ITGA2; integrin alpha 2
K06476 ITGA2B; integrin alpha 2B
K06482 ITGA3; integrin alpha 3
K06485 ITGA6; integrin alpha 6
K06487 ITGAV; integrin alpha V
K05719 ITGB1; integrin beta 1
K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K09348 NKX3-1; homeobox protein Nkx-3.1
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04469 NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
K04735 RELA; transcription factor p65
K11987 PTGS2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
K02161 BCL2; apoptosis regulator Bcl-2
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04725 XIAP; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K03172 TRAF1; TNF receptor-associated factor 1
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K03174 TRAF3; TNF receptor-associated factor 3
K09848 TRAF4; TNF receptor-associated factor 4
K09849 TRAF5; TNF receptor-associated factor 5
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K07201 FOXO1; forkhead box protein O1
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53; tumor protein p53
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K08878 BCR1; breakpoint cluster region protein [EC:2.7.11.1]
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K04438 CRK; C-crk adapter molecule crk
K04438 CRK; C-crk adapter molecule crk
K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K04702 PIM1; proto-oncogene serine/threonine-protein kinase Pim-1 [EC:2.7.11.1]
K08806 PIM2; proto-oncogene serine/threonine-protein kinase Pim-2 [EC:2.7.11.1]
K03898 KNG; kininogen
K16366 EDN1; endothelin-1
K03915 BDKRB1; bradykinin receptor B1
K03916 BDKRB2; bradykinin receptor B2
K04197 EDNRA; endothelin receptor type A
K04198 EDNRB; endothelin receptor type B
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K05429 IL2; interleukin 2
K04736 IL3; interleukin 3
K05430 IL4; interleukin 4
K05428 IL5; interleukin 5
K05405 IL6; interleukin 6
K05431 IL7; interleukin 7
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05435 IL13; interleukin 13
K05433 IL15; interleukin 15
K05426 IL23A; interleukin 23 subunit alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K04687 IFNG; interferon gamma
K05068 IL2RA; interleukin 2 receptor alpha
K05069 IL2RB; interleukin 2 receptor beta
K05070 IL2RG; interleukin 2 receptor gamma
K04737 IL3RA; interleukin 3 receptor alpha
K05071 IL4R; interleukin 4 receptor
K04738 CSF2RB; cytokine receptor common subunit beta
K04738 CSF2RB; cytokine receptor common subunit beta
K05067 IL5RA; interleukin 5 receptor alpha
K05055 IL6R; interleukin 6 receptor
K05060 IL6ST; interleukin 6 signal transducer
K05072 IL7R; interleukin 7 receptor
K05063 IL12RB1; interleukin 12 receptor beta-1
K05064 IL12RB2; interleukin 12 receptor beta-2
K05076 IL13RA1; interleukin 13 receptor alpha-1
K05074 IL15RA; interleukin 15 receptor alpha
K05065 IL23R; interleukin 23 receptor
K05079 EPOR; erythropoietin receptor
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K05132 IFNGR1; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K15420 EML4; echinoderm microtubule-associated protein-like 4
K05119 ALK; anaplastic lymphoma kinase [EC:2.7.10.1]
K04350 RASGRP1; RAS guanyl-releasing protein 1
K12361 RASGRP2; RAS guanyl-releasing protein 2
K12362 RASGRP3; RAS guanyl-releasing protein 3
K12363 RASGRP4; RAS guanyl-releasing protein 4
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K11222 STAT4; signal transducer and activator of transcription 4
K11225 STAT6; signal transducer and activator of transcription 6
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K16859 PGF; placenta growth factor
K05449 VEGFC_D; vascular endothelial growth factor C/D
K05449 VEGFC_D; vascular endothelial growth factor C/D
K08774 TGFA; transforming growth factor, alpha
K04357 EGF; epidermal growth factor
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K17386 PDGFB; platelet-derived growth factor subunit B
K04363 PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05459 IGF1; insulin-like growth factor 1
K13769 IGF2; insulin-like growth factor 2
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K05461 KITLG; KIT ligand
K05091 KIT; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K05454 FLT3LG; fms-related tyrosine kinase 3 ligand
K05092 FLT3; fms-related tyrosine kinase 3 [EC:2.7.10.1]
K05460 HGF; hepatocyte growth factor
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K04362 FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04379 FOS; proto-oncogene protein c-fos
K02678 ETS1; C-ets-1
K01388 MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
K01398 MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K10030 IL8; interleukin 8
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K04445 RPS6KA5; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
K05126 RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
K09288 CCDC6; coiled-coil domain-containing protein 6
K09289 NCOA4; nuclear receptor coactivator 4
K03176 NTRK1; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K09290 TPM3; tropomyosin 3
K09291 TPR; nucleoprotein TPR
K09292 TFG; protein TFG
K09850 RASSF1; Ras association domain-containing protein 1
K08015 RASSF5; Ras association domain-containing protein 5
K04411 STK4; serine/threonine kinase 4
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K04375 ELK1; ETS domain-containing protein Elk-1
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K07834 RALA; Ras-related protein Ral-A
K07835 RALB; Ras-related protein Ral-B
K08773 RALBP1; RalA-binding protein 1
K04393 CDC42; cell division control protein 42
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K09293 PAX8; paired box protein 8
K08530 NR1C3; peroxisome proliferator-activated receptor gamma
K08524 RXRA; retinoid X receptor alpha
K08525 RXRB; retinoid X receptor beta
K08526 RXRG; retinoid X receptor gamma
K08528 RARB; retinoic acid receptor beta
K08550 ESR1; estrogen receptor alpha
K08551 ESR2; estrogen receptor beta
K09101 NCOA1; nuclear receptor coactivator 1 [EC:2.3.1.48]
K11256 NCOA3; nuclear receptor coactivator 3 [EC:2.3.1.48]
K04684 SP1; transcription factor Sp1
K04504 NR1C2; peroxisome proliferator-activated receptor delta
K10056 JUP; junction plakoglobin
K10055 ZBTB16; zinc finger and BTB domain-containing protein 16
K08527 RARA; retinoic acid receptor alpha
K06627 CCNA; cyclin-A
K06627 CCNA; cyclin-A
K10054 PML; E3 SUMO-protein ligase PML [EC:2.3.2.-]
K08367 RUNX1; runt-related transcription factor 1
K10053 RUNX1T1; CBFA2/RNUX1 translocation partner 1
K09438 SPI1; transcription factor PU.1
K09055 CEBPA; CCAAT/enhancer binding protein (C/EBP), alpha
K05066 CSF2RA; granulocyte-macrophage colony-stimulating factor receptor alpha
K05066 CSF2RA; granulocyte-macrophage colony-stimulating factor receptor alpha
K05061 CSF3R; granulocyte colony-stimulating factor receptor
K05090 CSF1R; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04453 MAX; Max protein
K10500 ZBTB17; zinc finger and BTB domain-containing protein 17
K04685 CDKN2B; cyclin-dependent kinase inhibitor 2B
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K02219 CKS1; cyclin-dependent kinase regulatory subunit CKS1
K02219 CKS1; cyclin-dependent kinase regulatory subunit CKS1
K03094 SKP1; S-phase kinase-associated protein 1
K03347 CUL1; cullin 1
K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
K03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K06618 RB1; retinoblastoma-associated protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]
K09455 MITF; microphthalmia-associated transcription factor
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04462 MECOM; [histone H3]-lysine9 N-methyltransferase (ecotropic virus integration site 1 protein) [EC:2.1.1.367]
K04496 CTBP; C-terminal binding protein [EC:1.1.1.428]
K04496 CTBP; C-terminal binding protein [EC:1.1.1.428]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K08734 MLH1; DNA mismatch repair protein MLH1
K08735 MSH2; DNA mismatch repair protein MSH2
K08736 MSH3; DNA mismatch repair protein MSH3
K08737 MSH6; DNA mismatch repair protein MSH6
K08775 BRCA2; breast cancer 2 susceptibility protein
K04482 RAD51; DNA repair protein RAD51
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K10131 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
K10132 BBC3; Bcl-2-binding component 3
K16341 BCL2L11; Bcl-2-like protein 11
K08738 CYC; cytochrome c
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04397 CASP7; caspase 7 [EC:3.4.22.60]
K10456 KLHL19; kelch-like protein 19
K05638 NFE2L2; nuclear factor erythroid 2-related factor 2
K00510 HMOX1; heme oxygenase 1 [EC:1.14.14.18]
K00355 NQO1; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K23790 GSTP; glutathione S-transferase P [EC:2.5.1.18]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K03871 VHL; von Hippel-Lindau disease tumor supressor
K03872 ELOC; elongin-C
K03873 ELOB; elongin-B
K03870 CUL2; cullin 2
K09592 EGLN; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K09592 EGLN; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K09592 EGLN; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K09095 HIF2A; hypoxia-inducible factor 2 alpha
K09097 ARNT; aryl hydrocarbon receptor nuclear translocator
K15589 ARNT2; aryl hydrocarbon receptor nuclear translocator 2
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K07299 SLC2A1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
K06052 JAG1; jagged-1
K06051 DLL; delta
K06051 DLL; delta
K06051 DLL; delta
K02599 NOTCH1; Notch 1
K20994 NOTCH2; Notch 2
K20995 NOTCH3; Notch 3
K20996 NOTCH4; Notch 4
K06054 HES1; hairy and enhancer of split 1
K06055 HES5; hairy and enhancer of split 5
K09091 HEY; hairy and enhancer of split related with YRPW motif
K09091 HEY; hairy and enhancer of split related with YRPW motif
K09091 HEY; hairy and enhancer of split related with YRPW motif
K05097 FLT4; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K11988 SHH; sonic hedgehog
K06225 PTCH1; patched 1
K06226 SMO; smoothened
K18806 KIF7; kinesin family member 7
K18806 KIF7; kinesin family member 7
K06229 SUFU; suppressor of fused
K16797 GLI1; zinc finger protein GLI1
K16798 GLI2; zinc finger protein GLI2
K06230 GLI3; zinc finger protein GLI3
K21283 BMP2; bone morphogenetic protein 2
K04662 BMP4; bone morphogenetic protein 4
K06231 HHIP; hedgehog interacting protein
K11101 PTCH2; patched 2
K08557 AR; androgen receptor
K04079 HSP90A; molecular chaperone HtpG
K04079 HSP90A; molecular chaperone HtpG
K09487 HSP90B; heat shock protein 90kDa beta

     05202 Transcriptional misregulation in cancer [PATH:lav05202]

     05206 MicroRNAs in cancer [PATH:lav05206]

     05205 Proteoglycans in cancer [PATH:lav05205]

     05204 Chemical carcinogenesis - DNA adducts [PATH:lav05204]

     05207 Chemical carcinogenesis - receptor activation [PATH:lav05207]

       100656157 CHRNA7-FAM7A fusion protein
       100665736 ARRB1; beta-arrestin-1 isoform X6
       100660311 ARRB2; beta-arrestin-2 isoform X1
       100675475 SRC; proto-oncogene tyrosine-protein kinase Src
       100655727 RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X1
       100673196 RB1; retinoblastoma-associated protein
       100664468 E2F1; LOW QUALITY PROTEIN: transcription factor E2F1
       100671026 BIRC5; baculoviral IAP repeat-containing protein 5
       100657657 XIAP; E3 ubiquitin-protein ligase XIAP
       100666475 CDC6; cell division control protein 6 homolog
       100659991 CDC25A; M-phase inducer phosphatase 1 isoform X1
       100676652 JAK2; tyrosine-protein kinase JAK2 isoform X1
       100669583 STAT3; signal transducer and activator of transcription 3 isoform X2
       100663886 IKBKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform X3
       100669703 CCND1; G1/S-specific cyclin-D1
       100664510 CHRNA4; neuronal acetylcholine receptor subunit alpha-4
       100677002 CHRNB2; neuronal acetylcholine receptor subunit beta-2
       100674819 CHRNA3; neuronal acetylcholine receptor subunit alpha-3 isoform X2
       100674530 CHRNB4; neuronal acetylcholine receptor subunit beta-4
       100659992 CACNA1D; LOW QUALITY PROTEIN: voltage-dependent L-type calcium channel subunit alpha-1D
       100674649 CACNA1F; LOW QUALITY PROTEIN: voltage-dependent L-type calcium channel subunit alpha-1F
       100673089 CACNA1S; LOW QUALITY PROTEIN: voltage-dependent L-type calcium channel subunit alpha-1S
       100660444 CACNA1B; voltage-dependent N-type calcium channel subunit alpha-1B
       100655176 CACNA1A; LOW QUALITY PROTEIN: voltage-dependent P/Q-type calcium channel subunit alpha-1A
       100657948 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
       100658340 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1
       100666266 PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
       100653731 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1
       100665045 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
       100675496 PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma
       100663184 AKT2; RAC-beta serine/threonine-protein kinase isoform X1
       100657536 AKT3; RAC-gamma serine/threonine-protein kinase isoform X2
       100660187 AKT1; RAC-alpha serine/threonine-protein kinase
       100660112 MTOR; LOW QUALITY PROTEIN: serine/threonine-protein kinase mTOR
       100662194 NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1
       100654730 RELA; transcription factor p65 isoform X2
       100661512 KRAS; GTPase KRas isoform X2
       100659051 NRAS; GTPase NRas
       100667623 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1
       100657587 MAP2K2; dual specificity mitogen-activated protein kinase kinase 2
       100658240 MAPK3; mitogen-activated protein kinase 3
       100665157 MAPK1; mitogen-activated protein kinase 1
       100674799 FOS; LOW QUALITY PROTEIN: proto-oncogene c-Fos
       100670432 JUN; transcription factor AP-1
       100665874 MYC; myc proto-oncogene protein
       100675268 BCL2; apoptosis regulator Bcl-2
       100665537 PRKCA; protein kinase C alpha type isoform X1
       100672078 PRKCB; LOW QUALITY PROTEIN: protein kinase C beta type
       100671733 PRKCG; LOW QUALITY PROTEIN: protein kinase C gamma type
       100661392 VEGFA; vascular endothelial growth factor A
       100657533 FGF2; fibroblast growth factor 2
       100654973 ADRB1; LOW QUALITY PROTEIN: beta-1 adrenergic receptor
       100664615 ADRB2; beta-2 adrenergic receptor
       100674524 ADRB3; beta-3 adrenergic receptor
       100655206 guanine nucleotide-binding protein G(s) subunit alpha isoform X1
       100669226 neuroendocrine secretory protein 55-like
       100671072 ADCY1; adenylate cyclase type 1
       100673570 ADCY2; LOW QUALITY PROTEIN: adenylate cyclase type 2
       100674724 ADCY3; adenylate cyclase type 3
       100675525 ADCY4; adenylate cyclase type 4
       100670244 ADCY5; LOW QUALITY PROTEIN: adenylate cyclase type 5
       100653532 ADCY6; adenylate cyclase type 6 isoform X1
       100653771 ADCY7; adenylate cyclase type 7 isoform X1
       100661616 ADCY8; adenylate cyclase type 8
       100663448 ADCY9; LOW QUALITY PROTEIN: adenylate cyclase type 9
       100656966 PRKACB; cAMP-dependent protein kinase catalytic subunit beta isoform X1
       100674245 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha
       100675162 CREB1; cyclic AMP-responsive element-binding protein 1 isoform X1
       100657989 ATF2; cyclic AMP-dependent transcription factor ATF-2 isoform X1
       100662521 ATF4; cyclic AMP-dependent transcription factor ATF-4 isoform X2
       100653565 CREB3L1; cyclic AMP-responsive element-binding protein 3-like protein 1
       100673694 CREB3L4; cyclic AMP-responsive element-binding protein 3-like protein 4
       100666211 CREB3L2; cyclic AMP-responsive element-binding protein 3-like protein 2
       100670574 CREB3L3; cyclic AMP-responsive element-binding protein 3-like protein 3
       100677344 CREB3; cyclic AMP-responsive element-binding protein 3 isoform X1
       100675079 CREB5; cyclic AMP-responsive element-binding protein 5 isoform X1
       100666885 ATF6B; cyclic AMP-dependent transcription factor ATF-6 beta isoform X2
       100666344 GNAI1; guanine nucleotide-binding protein G(i) subunit alpha-1
       100670234 GNAI2; guanine nucleotide-binding protein G(i) subunit alpha-2
       100667957 GNAI3; LOW QUALITY PROTEIN: guanine nucleotide-binding protein G(k) subunit alpha
       100668387 BAD; bcl2-associated agonist of cell death
       100661433 CHRNA9; neuronal acetylcholine receptor subunit alpha-9
       100654322 RPS6KA6; ribosomal protein S6 kinase alpha-6 isoform X1
       100658801 RPS6KA2; ribosomal protein S6 kinase alpha-2 isoform X1
       100659843 RPS6KA3; ribosomal protein S6 kinase alpha-3
       100676062 RPS6KA1; LOW QUALITY PROTEIN: ribosomal protein S6 kinase alpha-1
       100677316 ESR1; estrogen receptor
       100677158 ESR2; estrogen receptor beta
       100675066 VDR; vitamin D3 receptor isoform X2
       100668683 CCND3; G1/S-specific cyclin-D3 isoform X1
       100659125 EGFR; epidermal growth factor receptor isoform X1
       100655474 GRB2; growth factor receptor-bound protein 2
       100657379 SOS1; LOW QUALITY PROTEIN: son of sevenless homolog 1
       100656200 SOS2; son of sevenless homolog 2 isoform X1
       100665518 EIF4EBP1; eukaryotic translation initiation factor 4E-binding protein 1
       100653946 RPS6KB1; ribosomal protein S6 kinase beta-1 isoform X1
       100671034 RPS6KB2; ribosomal protein S6 kinase beta-2 isoform X1
       100670353 PAQR7; membrane progestin receptor alpha
       100672192 PAQR8; membrane progestin receptor beta isoform X2
       100658223 PAQR5; LOW QUALITY PROTEIN: membrane progestin receptor gamma
       100658131 PGR; LOW QUALITY PROTEIN: progesterone receptor
       100663523 TNFSF11; tumor necrosis factor ligand superfamily member 11
       100672448 signal transducer and activator of transcription 5A
       100669299 STAT5B; signal transducer and activator of transcription 5B isoform X1
       100656694 BCL6; B-cell lymphoma 6 protein isoform X1
       100657633 KLF5; Krueppel-like factor 5
       100671451 KLF4; Krueppel-like factor 4 isoform X2
       100665966 NOTCH2; neurogenic locus notch homolog protein 2 isoform X2
       100658294 JAG1; LOW QUALITY PROTEIN: protein jagged-1
       100667886 AR; androgen receptor isoform X1
       100670137 EGF; LOW QUALITY PROTEIN: pro-epidermal growth factor
       100663120 FGF10; fibroblast growth factor 10
       100668915 FGF6; fibroblast growth factor 6
       100658495 FGF16; LOW QUALITY PROTEIN: fibroblast growth factor 16
       100675766 FGF17; fibroblast growth factor 17 isoform X1
       100671479 FGF9; fibroblast growth factor 9
       100672847 FGF7; fibroblast growth factor 7
       100668860 FGF4; fibroblast growth factor 4
       100662939 FGF8; fibroblast growth factor 8
       100656834 FGF18; LOW QUALITY PROTEIN: fibroblast growth factor 18
       100656129 FGF5; fibroblast growth factor 5
       100669156 FGF22; LOW QUALITY PROTEIN: fibroblast growth factor 22
       100656791 FGF20; fibroblast growth factor 20
       100671694 DLL4; delta-like protein 4
       100662144 DLL3; delta-like protein 3
       100654838 DLL1; LOW QUALITY PROTEIN: delta-like protein 1
       100657504 PTGES3; prostaglandin E synthase 3
       100677666 AIPL1; aryl-hydrocarbon-interacting protein-like 1
       100672942 AIP; AH receptor-interacting protein isoform X1
       104847035 aryl hydrocarbon receptor-like
       100664247 AHR; aryl hydrocarbon receptor
       100656361 HSP90AB1; heat shock protein HSP 90-beta
       100676217 HSP90AA1; LOW QUALITY PROTEIN: heat shock protein HSP 90-alpha
       100670864 HSP90B1; endoplasmin
       100655457 KPNA1; importin subunit alpha-5
       100667905 KPNA2; importin subunit alpha-1 isoform X1
       100667047 KPNA7; importin subunit alpha-8
       100664002 KPNA4; LOW QUALITY PROTEIN: importin subunit alpha-3
       100674915 KPNA3; importin subunit alpha-4 isoform X2
       100659673 importin subunit alpha-6 isoform X1
       100665420 KPNA6; importin subunit alpha-7 isoform X1
       100677082 KPNB1; importin subunit beta-1
       100673667 ARNT; aryl hydrocarbon receptor nuclear translocator isoform X6
       100665901 cytochrome P450 1A1
       100655003 LOW QUALITY PROTEIN: cytochrome P450 1B1
       100673770 EPHX1; epoxide hydrolase 1
       100658579 EPHX2; bifunctional epoxide hydrolase 2 isoform X1
       100672531 EPHX3; epoxide hydrolase 3
       100666859 EPHX4; epoxide hydrolase 4
       100672857 GSTA4; glutathione S-transferase A4 isoform X1
       100674860 glutathione S-transferase-like
       100673430 glutathione S-transferase A2
       100670476 glutathione S-transferase alpha-4-like
       100670760 glutathione S-transferase A1
       100675090 glutathione S-transferase omega-1
       100654951 MGST1; microsomal glutathione S-transferase 1
       100668813 glutathione S-transferase Mu 4-like isoform X1
       100669275 glutathione S-transferase Mu 1-like isoform X2
       100670040 glutathione S-transferase Mu 1 isoform X1
       100654410 MGST2; microsomal glutathione S-transferase 2
       100654331 MGST3; microsomal glutathione S-transferase 3
       100677494 glutathione S-transferase theta-1-like isoform X2
       100666638 glutathione S-transferase Mu 1-like
       100667211 GSTM3; glutathione S-transferase Mu 3
       100666921 uncharacterized protein LOC100666921
       100666354 glutathione S-transferase Mu 1-like
       100659524 glutathione S-transferase omega-2
       100675794 glutathione S-transferase theta-4
       100669866 UGT2A2; UDP-glucuronosyltransferase 2A2 isoform X3
       100670349 UDP-glucuronosyltransferase 2B31-like isoform X1
       100670816 UDP-glucuronosyltransferase 2B4-like isoform X1
       100671295 UDP-glucuronosyltransferase 2B4-like isoform X1
       100672057 UDP-glucuronosyltransferase 2B31-like isoform X1
       100672537 UDP-glucuronosyltransferase 2B4-like isoform X1
       100663533 UDP-glucuronosyltransferase 2B31-like isoform X1
       100664001 UDP-glucuronosyltransferase 2B31-like isoform X1
       100664281 UDP-glucuronosyltransferase 2B17-like isoform X1
       100664768 UDP-glucuronosyltransferase 2B4-like isoform X5
       100665991 UDP-glucuronosyltransferase 2B31-like isoform X1
       100666277 UDP-glucuronosyltransferase 2B4-like isoform X1
       100677293 UDP-glucuronosyltransferase 2B31-like isoform X1
       100664273 UDP-glucuronosyltransferase 2B17-like
       100660608 UDP-glucuronosyltransferase 1-6-like isoform X1
       111752753 UDP-glucuronosyltransferase 1-1-like
       100659747 UDP-glucuronosyltransferase 1-3-like
       100658045 LOW QUALITY PROTEIN: UDP-glucuronosyltransferase 1-6
       100665534 UDP-glucuronosyltransferase 2B31-like
       100663710 UDP-glucuronosyltransferase 2B17-like
       100662036 LOW QUALITY PROTEIN: UDP-glucuronosyltransferase 1-10-like
       100662603 UDP-glucuronosyltransferase 1-10-like
       100662881 UDP-glucuronosyltransferase 1-10-like
       100662317 UDP-glucuronosyltransferase 1-10-like
       100663166 LOW QUALITY PROTEIN: UDP-glucuronosyltransferase 1-10-like
       100667350 cytochrome P450 2B11-like
       100677786 LOW QUALITY PROTEIN: cytochrome P450 2B11-like
       100655283 NR1I3; nuclear receptor subfamily 1 group I member 3
       100674208 retinoic acid receptor RXR-alpha-like
       100662699 RXRB; retinoic acid receptor RXR-beta isoform X2
       100653765 RXRG; retinoic acid receptor RXR-gamma
       100658793 cytochrome P450 3A9-like
       100677295 cytochrome P450 3A8-like isoform X2
       100658511 cytochrome P450 3A21-like
       100677576 cytochrome P450 3A12-like isoform X2
       100666189 cytochrome P450 1A2 isoform X1
       100657770 PPARA; peroxisome proliferator-activated receptor alpha isoform X1

K04809 CHRNA7; nicotinic acetylcholine receptor alpha-7
K04439 ARRB; beta-arrestin
K04439 ARRB; beta-arrestin
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K08731 BIRC5; baculoviral IAP repeat-containing protein 5
K04725 XIAP; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K02213 CDC6; cell division control protein 6
K06645 CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K07211 IKBKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
K04503 CCND1; G1/S-specific cyclin-D1
K04806 CHRNA4; nicotinic acetylcholine receptor alpha-4
K04813 CHRNB2; nicotinic acetylcholine receptor beta-2
K04805 CHRNA3; nicotinic acetylcholine receptor alpha-3
K04815 CHRNB4; nicotinic acetylcholine receptor beta-4
K04851 CACNA1D; voltage-dependent calcium channel L type alpha-1D
K04853 CACNA1F; voltage-dependent calcium channel L type alpha-1F
K04857 CACNA1S; voltage-dependent calcium channel L type alpha-1S
K04849 CACNA1B; voltage-dependent calcium channel N type alpha-1B
K04344 CACNA1A; voltage-dependent calcium channel P/Q type alpha-1A
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04379 FOS; proto-oncogene protein c-fos
K04448 JUN; transcription factor AP-1
K04377 MYC; Myc proto-oncogene protein
K02161 BCL2; apoptosis regulator Bcl-2
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K05448 VEGFA; vascular endothelial growth factor A
K18497 FGF2; fibroblast growth factor 2
K04141 ADRB1; adrenergic receptor beta-1
K04142 ADRB2; adrenergic receptor beta-2
K04143 ADRB3; adrenergic receptor beta-3
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04450 ATF2; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B; cyclic AMP-dependent transcription factor ATF-6 beta
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K02158 BAD; Bcl-2-antagonist of cell death
K04810 CHRNA9; nicotinic acetylcholine receptor alpha-9
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K08550 ESR1; estrogen receptor alpha
K08551 ESR2; estrogen receptor beta
K08539 VDR; vitamin D3 receptor
K10152 CCND3; G1/S-specific cyclin-D3
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K25039 PAQR7; membrane progestin receptor alpha
K25040 PAQR8; membrane progestin receptor beta
K25041 PAQR5; membrane progestin receptor gamma
K08556 PGR; progesterone receptor
K05473 TNFSF11; tumor necrosis factor ligand superfamily member 11
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K15618 BCL6; B-cell lymphoma 6 protein
K09206 KLF5; krueppel-like factor 5
K17846 KLF4; krueppel-like factor 4
K20994 NOTCH2; Notch 2
K06052 JAG1; jagged-1
K08557 AR; androgen receptor
K04357 EGF; epidermal growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K06051 DLL; delta
K06051 DLL; delta
K06051 DLL; delta
K15730 PTGES3; cytosolic prostaglandin-E synthase [EC:5.3.99.3]
K17767 AIP; AH receptor-interacting protein
K17767 AIP; AH receptor-interacting protein
K09093 AHR; aryl hydrocarbon receptor
K09093 AHR; aryl hydrocarbon receptor
K04079 HSP90A; molecular chaperone HtpG
K04079 HSP90A; molecular chaperone HtpG
K09487 HSP90B; heat shock protein 90kDa beta
K23940 KPNA1; importin subunit alpha-5
K15043 KPNA2_7; importin subunit alpha-1/8
K15043 KPNA2_7; importin subunit alpha-1/8
K23583 KPNA3_4; importin subunit alpha-4/3
K23583 KPNA3_4; importin subunit alpha-4/3
K15042 KPNA5_6; importin subunit alpha-6/7
K15042 KPNA5_6; importin subunit alpha-6/7
K14293 KPNB1; importin subunit beta-1
K09097 ARNT; aryl hydrocarbon receptor nuclear translocator
K07408 CYP1A1; cytochrome P450 family 1 subfamily A1 [EC:1.14.14.1]
K07410 CYP1B1; cytochrome P450 family 1 subfamily B1 [EC:1.14.14.1]
K01253 EPHX1; microsomal epoxide hydrolase [EC:3.3.2.9]
K08726 EPHX2; soluble epoxide hydrolase / lipid-phosphate phosphatase [EC:3.3.2.10 3.1.3.76]
K22368 EPHX3; epoxide hydrolase 3 [EC:3.3.2.10]
K22369 EPHX4; epoxide hydrolase 4 [EC:3.3.-.-]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K07412 CYP2B; cytochrome P450 family 2 subfamily B [EC:1.14.14.1]
K07412 CYP2B; cytochrome P450 family 2 subfamily B [EC:1.14.14.1]
K08541 NR1I3; constitutive androstane receptor
K08524 RXRA; retinoid X receptor alpha
K08525 RXRB; retinoid X receptor beta
K08526 RXRG; retinoid X receptor gamma
K07424 CYP3A; cytochrome P450 family 3 subfamily A [EC:1.14.14.1]
K07424 CYP3A; cytochrome P450 family 3 subfamily A [EC:1.14.14.1]
K07424 CYP3A; cytochrome P450 family 3 subfamily A [EC:1.14.14.1]
K07424 CYP3A; cytochrome P450 family 3 subfamily A [EC:1.14.14.1]
K07409 CYP1A2; cytochrome P450 family 1 subfamily A2 [EC:1.14.14.1]
K07294 NR1C1; peroxisome proliferator-activated receptor alpha

     05208 Chemical carcinogenesis - reactive oxygen species [PATH:lav05208]

     05203 Viral carcinogenesis [PATH:lav05203]

     05230 Central carbon metabolism in cancer [PATH:lav05230]

     05231 Choline metabolism in cancer [PATH:lav05231]

     05235 PD-L1 expression and PD-1 checkpoint pathway in cancer [PATH:lav05235]

   09162 Cancer: specific types

     05210 Colorectal cancer [PATH:lav05210]

     05212 Pancreatic cancer [PATH:lav05212]

     05225 Hepatocellular carcinoma [PATH:lav05225]

     05226 Gastric cancer [PATH:lav05226]

     05214 Glioma [PATH:lav05214]

     05216 Thyroid cancer [PATH:lav05216]

     05221 Acute myeloid leukemia [PATH:lav05221]

     05220 Chronic myeloid leukemia [PATH:lav05220]

     05217 Basal cell carcinoma [PATH:lav05217]

     05218 Melanoma [PATH:lav05218]

     05211 Renal cell carcinoma [PATH:lav05211]

     05219 Bladder cancer [PATH:lav05219]

     05215 Prostate cancer [PATH:lav05215]

     05213 Endometrial cancer [PATH:lav05213]

     05224 Breast cancer [PATH:lav05224]

       100677316 ESR1; estrogen receptor
       100677158 ESR2; estrogen receptor beta
       100673959 NCOA1; nuclear receptor coactivator 1 isoform X3
       100668174 NCOA3; nuclear receptor coactivator 3 isoform X1
       100674799 FOS; LOW QUALITY PROTEIN: proto-oncogene c-Fos
       100670432 JUN; transcription factor AP-1
       100662543 SP1; transcription factor Sp1
       100669703 CCND1; G1/S-specific cyclin-D1
       100665874 MYC; myc proto-oncogene protein
       100658131 PGR; LOW QUALITY PROTEIN: progesterone receptor
       100664388 WNT4; LOW QUALITY PROTEIN: protein Wnt-4
       100663523 TNFSF11; tumor necrosis factor ligand superfamily member 11
       100662583 ERBB2; receptor tyrosine-protein kinase erbB-2 isoform X2
       100663763 FGF1; fibroblast growth factor 1
       100657533 FGF2; fibroblast growth factor 2
       100663120 FGF10; fibroblast growth factor 10
       100668915 FGF6; fibroblast growth factor 6
       100658495 FGF16; LOW QUALITY PROTEIN: fibroblast growth factor 16
       100675766 FGF17; fibroblast growth factor 17 isoform X1
       100671479 FGF9; fibroblast growth factor 9
       100672847 FGF7; fibroblast growth factor 7
       100668860 FGF4; fibroblast growth factor 4
       100662939 FGF8; fibroblast growth factor 8
       100656834 FGF18; LOW QUALITY PROTEIN: fibroblast growth factor 18
       100656129 FGF5; fibroblast growth factor 5
       100669156 FGF22; LOW QUALITY PROTEIN: fibroblast growth factor 22
       100656791 FGF20; fibroblast growth factor 20
       100661893 FGF21; LOW QUALITY PROTEIN: fibroblast growth factor 21
       100668635 FGF23; fibroblast growth factor 23
       100662289 FGFR1; fibroblast growth factor receptor 1 isoform X3
       100664710 IGF1; insulin-like growth factor I isoform X1
       100655087 IGF1R; insulin-like growth factor 1 receptor
       100670137 EGF; LOW QUALITY PROTEIN: pro-epidermal growth factor
       100659125 EGFR; epidermal growth factor receptor isoform X1
       100655943 KIT; mast/stem cell growth factor receptor Kit isoform X2
       100653766 SHC1; SHC-transforming protein 1 isoform X2
       100659669 SHC3; SHC-transforming protein 3
       100654827 SHC4; SHC-transforming protein 4
       100655474 GRB2; growth factor receptor-bound protein 2
       100657379 SOS1; LOW QUALITY PROTEIN: son of sevenless homolog 1
       100656200 SOS2; son of sevenless homolog 2 isoform X1
       100661512 KRAS; GTPase KRas isoform X2
       100659051 NRAS; GTPase NRas
       100671404 ARAF; serine/threonine-protein kinase A-Raf isoform X3
       100664119 BRAF; serine/threonine-protein kinase B-raf
       100655727 RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X1
       100667623 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1
       100657587 MAP2K2; dual specificity mitogen-activated protein kinase kinase 2
       100658240 MAPK3; mitogen-activated protein kinase 3
       100665157 MAPK1; mitogen-activated protein kinase 1
       100657948 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
       100658340 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1
       100666266 PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
       100653731 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1
       100665045 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
       100675496 PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma
       100660561 PTEN; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X1
       100663184 AKT2; RAC-beta serine/threonine-protein kinase isoform X1
       100657536 AKT3; RAC-gamma serine/threonine-protein kinase isoform X2
       100660187 AKT1; RAC-alpha serine/threonine-protein kinase
       100660112 MTOR; LOW QUALITY PROTEIN: serine/threonine-protein kinase mTOR
       100653946 RPS6KB1; ribosomal protein S6 kinase beta-1 isoform X1
       100671034 RPS6KB2; ribosomal protein S6 kinase beta-2 isoform X1
       100658294 JAG1; LOW QUALITY PROTEIN: protein jagged-1
       100671694 DLL4; delta-like protein 4
       100662144 DLL3; delta-like protein 3
       100654838 DLL1; LOW QUALITY PROTEIN: delta-like protein 1
       100659212 NOTCH1; neurogenic locus notch homolog protein 1
       100665966 NOTCH2; neurogenic locus notch homolog protein 2 isoform X2
       100661550 NOTCH3; LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 3
       100656367 NOTCH4; LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 4
       100660397 HES1; transcription factor HES-1
       100675106 HES5; transcription factor HES-5
       100661585 HEY2; hairy/enhancer-of-split related with YRPW motif protein 2 isoform X1
       100657428 HEY1; hairy/enhancer-of-split related with YRPW motif protein 1 isoform X2
       100660120 HEYL; LOW QUALITY PROTEIN: hairy/enhancer-of-split related with YRPW motif-like protein
       100677038 FLT4; LOW QUALITY PROTEIN: vascular endothelial growth factor receptor 3
       100671706 CDKN1A; cyclin-dependent kinase inhibitor 1
       100657917 NFKB2; nuclear factor NF-kappa-B p100 subunit isoform X2
       100653551 WNT2B; protein Wnt-2b
       100657046 WNT2; protein Wnt-2
       100663058 WNT3; proto-oncogene Wnt-3
       100662337 WNT3A; protein Wnt-3a
       100664544 WNT5B; protein Wnt-5b isoform X2
       100658849 WNT5A; protein Wnt-5a isoform X1
       100675069 WNT6; protein Wnt-6
       100675463 WNT7A; protein Wnt-7a
       100660629 WNT7B; protein Wnt-7b
       100665788 WNT8B; protein Wnt-8b
       100668409 WNT8A; protein Wnt-8a
       100658979 WNT9B; protein Wnt-9b
       100662057 WNT9A; protein Wnt-9a
       100674782 WNT10A; protein Wnt-10a
       100655805 WNT10B; protein Wnt-10b
       100656630 WNT11; protein Wnt-11
       100659037 WNT16; protein Wnt-16
       100657335 FZD1; frizzled-1
       100658936 FZD7; frizzled-7
       100654997 FZD2; frizzled-2
       100666465 FZD3; frizzled-3
       100675317 FZD4; frizzled-4
       100674586 FZD5; frizzled-5
       100666499 FZD8; LOW QUALITY PROTEIN: frizzled-8
       100677440 FZD6; frizzled-6
       100660631 FZD10; frizzled-10
       100658734 LRP6; LOW QUALITY PROTEIN: low-density lipoprotein receptor-related protein 6
       100666209 LRP5; LOW QUALITY PROTEIN: low-density lipoprotein receptor-related protein 5
       100673586 DVL3; segment polarity protein dishevelled homolog DVL-3 isoform X1
       100657749 DVL2; segment polarity protein dishevelled homolog DVL-2 isoform X1
       100657649 DVL1; segment polarity protein dishevelled homolog DVL-1 isoform X1
       100669466 FRAT1; proto-oncogene FRAT1
       100669183 FRAT2; GSK-3-binding protein FRAT2
       100675105 GSK3B; glycogen synthase kinase-3 beta isoform X2
       100655765 AXIN1; axin-1
       100663921 AXIN2; axin-2
       100659017 APC; adenomatous polyposis coli protein isoform X2
       100670988 CTNNB1; LOW QUALITY PROTEIN: catenin beta-1
       100669057 CSNK1A1; casein kinase I isoform X3
       100663559 TCF7; transcription factor 7 isoform X3
       100656106 TCF7L2; transcription factor 7-like 2 isoform X22
       100658960 LEF1; lymphoid enhancer-binding factor 1 isoform X2
       100663725 TP53; cellular tumor antigen p53 isoform X1
       100658253 GADD45G; growth arrest and DNA damage-inducible protein GADD45 gamma
       100655692 GADD45B; growth arrest and DNA damage-inducible protein GADD45 beta isoform X2
       100653562 GADD45A; growth arrest and DNA damage-inducible protein GADD45 alpha
       100673560 BAX; apoptosis regulator BAX
       100669799 BAK1; bcl-2 homologous antagonist/killer
       100665802 DDB2; DNA damage-binding protein 2 isoform X1
       100662275 POLK; DNA polymerase kappa isoform X2
       104847103 CDK4; cyclin-dependent kinase 4
       100655429 CDK6; cyclin-dependent kinase 6 isoform X1
       100673196 RB1; retinoblastoma-associated protein
       100664468 E2F1; LOW QUALITY PROTEIN: transcription factor E2F1
       100665816 E2F2; transcription factor E2F2 isoform X1
       100656140 E2F3; transcription factor E2F3 isoform X1
       100653763 BRCA1; breast cancer type 1 susceptibility protein
       100669658 BRCA2; LOW QUALITY PROTEIN: breast cancer type 2 susceptibility protein

K08550 ESR1; estrogen receptor alpha
K08551 ESR2; estrogen receptor beta
K09101 NCOA1; nuclear receptor coactivator 1 [EC:2.3.1.48]
K11256 NCOA3; nuclear receptor coactivator 3 [EC:2.3.1.48]
K04379 FOS; proto-oncogene protein c-fos
K04448 JUN; transcription factor AP-1
K04684 SP1; transcription factor Sp1
K04503 CCND1; G1/S-specific cyclin-D1
K04377 MYC; Myc proto-oncogene protein
K08556 PGR; progesterone receptor
K00408 WNT4; wingless-type MMTV integration site family, member 4
K05473 TNFSF11; tumor necrosis factor ligand superfamily member 11
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K04362 FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05459 IGF1; insulin-like growth factor 1
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04357 EGF; epidermal growth factor
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05091 KIT; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K06279 SHC1; SHC-transforming protein 1
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K06052 JAG1; jagged-1
K06051 DLL; delta
K06051 DLL; delta
K06051 DLL; delta
K02599 NOTCH1; Notch 1
K20994 NOTCH2; Notch 2
K20995 NOTCH3; Notch 3
K20996 NOTCH4; Notch 4
K06054 HES1; hairy and enhancer of split 1
K06055 HES5; hairy and enhancer of split 5
K09091 HEY; hairy and enhancer of split related with YRPW motif
K09091 HEY; hairy and enhancer of split related with YRPW motif
K09091 HEY; hairy and enhancer of split related with YRPW motif
K05097 FLT4; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04469 NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7; frizzled 1/7
K02432 FZD1_7; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4; frizzled 4
K02375 FZD5_8; frizzled 5/8
K02375 FZD5_8; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10; frizzled 9/10
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K03069 FRAT1; frequently rearranged in advanced T-cell lymphomas 1
K03096 FRAT2; frequently rearranged in advanced T-cell lymphomas 2
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02085 APC; adenomatosis polyposis coli protein
K02105 CTNNB1; catenin beta 1
K08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]
K02620 TCF7; transcription factor 7
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K04451 TP53; tumor protein p53
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
K08775 BRCA2; breast cancer 2 susceptibility protein

     05222 Small cell lung cancer [PATH:lav05222]

     05223 Non-small cell lung cancer [PATH:lav05223]

   09172 Infectious disease: viral

   09171 Infectious disease: bacterial

   09174 Infectious disease: parasitic

   09163 Immune disease

   09164 Neurodegenerative disease

   09165 Substance dependence

   09166 Cardiovascular disease

   09167 Endocrine and metabolic disease

   09175 Drug resistance: antimicrobial

   09176 Drug resistance: antineoplastic

     01521 EGFR tyrosine kinase inhibitor resistance [PATH:lav01521]

     01524 Platinum drug resistance [PATH:lav01524]

     01523 Antifolate resistance [PATH:lav01523]

     01522 Endocrine resistance [PATH:lav01522]

       100670112 ABCB11; LOW QUALITY PROTEIN: bile salt export pump
       100677316 ESR1; estrogen receptor
       100677158 ESR2; estrogen receptor beta
       100668174 NCOA3; nuclear receptor coactivator 3 isoform X1
       100660695 MED1; mediator of RNA polymerase II transcription subunit 1 isoform X1
       100669672 CARM1; histone-arginine methyltransferase CARM1 isoform X1
       100674799 FOS; LOW QUALITY PROTEIN: proto-oncogene c-Fos
       100670432 JUN; transcription factor AP-1
       100662543 SP1; transcription factor Sp1
       100669709 NCOR1; LOW QUALITY PROTEIN: nuclear receptor corepressor 1
       100677095 GPER1; G-protein coupled estrogen receptor 1
       100655206 guanine nucleotide-binding protein G(s) subunit alpha isoform X1
       100669226 neuroendocrine secretory protein 55-like
       100675475 SRC; proto-oncogene tyrosine-protein kinase Src
       100659450 MMP2; 72 kDa type IV collagenase
       100664260 MMP9; LOW QUALITY PROTEIN: matrix metalloproteinase-9
       100675899 HBEGF; proheparin-binding EGF-like growth factor isoform X2
       100671072 ADCY1; adenylate cyclase type 1
       100673570 ADCY2; LOW QUALITY PROTEIN: adenylate cyclase type 2
       100674724 ADCY3; adenylate cyclase type 3
       100675525 ADCY4; adenylate cyclase type 4
       100670244 ADCY5; LOW QUALITY PROTEIN: adenylate cyclase type 5
       100653532 ADCY6; adenylate cyclase type 6 isoform X1
       100653771 ADCY7; adenylate cyclase type 7 isoform X1
       100661616 ADCY8; adenylate cyclase type 8
       100663448 ADCY9; LOW QUALITY PROTEIN: adenylate cyclase type 9
       100656966 PRKACB; cAMP-dependent protein kinase catalytic subunit beta isoform X1
       100674245 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha
       100659125 EGFR; epidermal growth factor receptor isoform X1
       100662583 ERBB2; receptor tyrosine-protein kinase erbB-2 isoform X2
       100664710 IGF1; insulin-like growth factor I isoform X1
       100655087 IGF1R; insulin-like growth factor 1 receptor
       100653766 SHC1; SHC-transforming protein 1 isoform X2
       100659669 SHC3; SHC-transforming protein 3
       100654827 SHC4; SHC-transforming protein 4
       100655474 GRB2; growth factor receptor-bound protein 2
       100657379 SOS1; LOW QUALITY PROTEIN: son of sevenless homolog 1
       100656200 SOS2; son of sevenless homolog 2 isoform X1
       100661512 KRAS; GTPase KRas isoform X2
       100659051 NRAS; GTPase NRas
       100671404 ARAF; serine/threonine-protein kinase A-Raf isoform X3
       100664119 BRAF; serine/threonine-protein kinase B-raf
       100655727 RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X1
       100667623 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1
       100657587 MAP2K2; dual specificity mitogen-activated protein kinase kinase 2
       100658240 MAPK3; mitogen-activated protein kinase 3
       100665157 MAPK1; mitogen-activated protein kinase 1
       100657948 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
       100658340 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1
       100666266 PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
       100653731 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1
       100665045 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
       100675496 PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma
       100663184 AKT2; RAC-beta serine/threonine-protein kinase isoform X1
       100657536 AKT3; RAC-gamma serine/threonine-protein kinase isoform X2
       100660187 AKT1; RAC-alpha serine/threonine-protein kinase
       100660112 MTOR; LOW QUALITY PROTEIN: serine/threonine-protein kinase mTOR
       100653946 RPS6KB1; ribosomal protein S6 kinase beta-1 isoform X1
       100671034 RPS6KB2; ribosomal protein S6 kinase beta-2 isoform X1
       100668436 PTK2; LOW QUALITY PROTEIN: focal adhesion kinase 1
       100673331 MAPK14; mitogen-activated protein kinase 14 isoform X1
       100656926 MAPK13; mitogen-activated protein kinase 13
       100661039 MAPK12; mitogen-activated protein kinase 12 isoform X1
       100654943 MAPK9; mitogen-activated protein kinase 9 isoform X1
       100674229 MAPK8; mitogen-activated protein kinase 8 isoform X1
       100673395 MAPK10; mitogen-activated protein kinase 10 isoform X1
       100675268 BCL2; apoptosis regulator Bcl-2
       100673560 BAX; apoptosis regulator BAX
       100668387 BAD; bcl2-associated agonist of cell death
       111753233 BIK; bcl-2-interacting killer isoform X1
       100658294 JAG1; LOW QUALITY PROTEIN: protein jagged-1
       100671694 DLL4; delta-like protein 4
       100662144 DLL3; delta-like protein 3
       100654838 DLL1; LOW QUALITY PROTEIN: delta-like protein 1
       100659212 NOTCH1; neurogenic locus notch homolog protein 1
       100665966 NOTCH2; neurogenic locus notch homolog protein 2 isoform X2
       100661550 NOTCH3; LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 3
       100656367 NOTCH4; LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 4
       100669703 CCND1; G1/S-specific cyclin-D1
       104847103 CDK4; cyclin-dependent kinase 4
       100673196 RB1; retinoblastoma-associated protein
       100664468 E2F1; LOW QUALITY PROTEIN: transcription factor E2F1
       100665816 E2F2; transcription factor E2F2 isoform X1
       100656140 E2F3; transcription factor E2F3 isoform X1
       100669448 MDM2; E3 ubiquitin-protein ligase Mdm2 isoform X2
       100663725 TP53; cellular tumor antigen p53 isoform X1
       104845647 cyclin-dependent kinase inhibitor 2A-like
       100669475 CDKN2C; cyclin-dependent kinase 4 inhibitor C
       100671706 CDKN1A; cyclin-dependent kinase inhibitor 1
       100674125 CDKN1B; cyclin-dependent kinase inhibitor 1B

K05664 ABCB11; ATP-binding cassette, subfamily B (MDR/TAP), member 11
K08550 ESR1; estrogen receptor alpha
K08551 ESR2; estrogen receptor beta
K11256 NCOA3; nuclear receptor coactivator 3 [EC:2.3.1.48]
K15144 MED1; mediator of RNA polymerase II transcription subunit 1
K05931 CARM1; type I protein arginine methyltransferase [EC:2.1.1.319]
K04379 FOS; proto-oncogene protein c-fos
K04448 JUN; transcription factor AP-1
K04684 SP1; transcription factor Sp1
K04650 NCOR1; nuclear receptor co-repressor 1
K04246 GPER1; G-protein coupled estrogen receptor 1
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K01398 MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K08523 HBEGF; heparin-binding EGF-like growth factor
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K05459 IGF1; insulin-like growth factor 1
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K06279 SHC1; SHC-transforming protein 1
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K02161 BCL2; apoptosis regulator Bcl-2
K02159 BAX; apoptosis regulator BAX
K02158 BAD; Bcl-2-antagonist of cell death
K18452 BIK; Bcl-2-interacting killer
K06052 JAG1; jagged-1
K06051 DLL; delta
K06051 DLL; delta
K06051 DLL; delta
K02599 NOTCH1; Notch 1
K20994 NOTCH2; Notch 2
K20995 NOTCH3; Notch 3
K20996 NOTCH4; Notch 4
K04503 CCND1; G1/S-specific cyclin-D1
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53; tumor protein p53
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K06622 CDKN2C; cyclin-dependent kinase inhibitor 2C
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B

 09180 Brite Hierarchies

 09190 Not Included in Pathway or Brite

[ KO | BRITE | KEGG2 | KEGG ]
Last updated: April 25, 2024