KEGG   ORTHOLOGY: K04441
Entry
K04441                      KO                                     
Symbol
P38
Name
p38 MAP kinase [EC:2.7.11.24]
Pathway
map01522  Endocrine resistance
map04010  MAPK signaling pathway
map04011  MAPK signaling pathway - yeast
map04013  MAPK signaling pathway - fly
map04015  Rap1 signaling pathway
map04068  FoxO signaling pathway
map04071  Sphingolipid signaling pathway
map04114  Oocyte meiosis
map04139  Mitophagy - yeast
map04212  Longevity regulating pathway - worm
map04218  Cellular senescence
map04261  Adrenergic signaling in cardiomyocytes
map04361  Axon regeneration
map04370  VEGF signaling pathway
map04380  Osteoclast differentiation
map04550  Signaling pathways regulating pluripotency of stem cells
map04611  Platelet activation
map04613  Neutrophil extracellular trap formation
map04620  Toll-like receptor signaling pathway
map04621  NOD-like receptor signaling pathway
map04622  RIG-I-like receptor signaling pathway
map04624  Toll and Imd signaling pathway
map04625  C-type lectin receptor signaling pathway
map04657  IL-17 signaling pathway
map04658  Th1 and Th2 cell differentiation
map04659  Th17 cell differentiation
map04660  T cell receptor signaling pathway
map04664  Fc epsilon RI signaling pathway
map04668  TNF signaling pathway
map04670  Leukocyte transendothelial migration
map04714  Thermogenesis
map04722  Neurotrophin signaling pathway
map04723  Retrograde endocannabinoid signaling
map04728  Dopaminergic synapse
map04750  Inflammatory mediator regulation of TRP channels
map04912  GnRH signaling pathway
map04914  Progesterone-mediated oocyte maturation
map04917  Prolactin signaling pathway
map04926  Relaxin signaling pathway
map04932  Non-alcoholic fatty liver disease
map04933  AGE-RAGE signaling pathway in diabetic complications
map04935  Growth hormone synthesis, secretion and action
map04936  Alcoholic liver disease
map05014  Amyotrophic lateral sclerosis
map05020  Prion disease
map05022  Pathways of neurodegeneration - multiple diseases
map05120  Epithelial cell signaling in Helicobacter pylori infection
map05130  Pathogenic Escherichia coli infection
map05131  Shigellosis
map05132  Salmonella infection
map05133  Pertussis
map05135  Yersinia infection
map05140  Leishmaniasis
map05142  Chagas disease
map05145  Toxoplasmosis
map05152  Tuberculosis
map05161  Hepatitis B
map05163  Human cytomegalovirus infection
map05167  Kaposi sarcoma-associated herpesvirus infection
map05169  Epstein-Barr virus infection
map05170  Human immunodeficiency virus 1 infection
map05171  Coronavirus disease - COVID-19
map05205  Proteoglycans in cancer
map05208  Chemical carcinogenesis - reactive oxygen species
map05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
map05415  Diabetic cardiomyopathy
map05417  Lipid and atherosclerosis
map05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K04441  P38; p38 MAP kinase
   04013 MAPK signaling pathway - fly
    K04441  P38; p38 MAP kinase
   04011 MAPK signaling pathway - yeast
    K04441  P38; p38 MAP kinase
   04015 Rap1 signaling pathway
    K04441  P38; p38 MAP kinase
   04370 VEGF signaling pathway
    K04441  P38; p38 MAP kinase
   04668 TNF signaling pathway
    K04441  P38; p38 MAP kinase
   04068 FoxO signaling pathway
    K04441  P38; p38 MAP kinase
   04071 Sphingolipid signaling pathway
    K04441  P38; p38 MAP kinase
 09140 Cellular Processes
  09141 Transport and catabolism
   04139 Mitophagy - yeast
    K04441  P38; p38 MAP kinase
  09143 Cell growth and death
   04114 Oocyte meiosis
    K04441  P38; p38 MAP kinase
   04218 Cellular senescence
    K04441  P38; p38 MAP kinase
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    K04441  P38; p38 MAP kinase
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    K04441  P38; p38 MAP kinase
   04613 Neutrophil extracellular trap formation
    K04441  P38; p38 MAP kinase
   04620 Toll-like receptor signaling pathway
    K04441  P38; p38 MAP kinase
   04624 Toll and Imd signaling pathway
    K04441  P38; p38 MAP kinase
   04621 NOD-like receptor signaling pathway
    K04441  P38; p38 MAP kinase
   04622 RIG-I-like receptor signaling pathway
    K04441  P38; p38 MAP kinase
   04625 C-type lectin receptor signaling pathway
    K04441  P38; p38 MAP kinase
   04660 T cell receptor signaling pathway
    K04441  P38; p38 MAP kinase
   04658 Th1 and Th2 cell differentiation
    K04441  P38; p38 MAP kinase
   04659 Th17 cell differentiation
    K04441  P38; p38 MAP kinase
   04657 IL-17 signaling pathway
    K04441  P38; p38 MAP kinase
   04664 Fc epsilon RI signaling pathway
    K04441  P38; p38 MAP kinase
   04670 Leukocyte transendothelial migration
    K04441  P38; p38 MAP kinase
  09152 Endocrine system
   04912 GnRH signaling pathway
    K04441  P38; p38 MAP kinase
   04914 Progesterone-mediated oocyte maturation
    K04441  P38; p38 MAP kinase
   04917 Prolactin signaling pathway
    K04441  P38; p38 MAP kinase
   04926 Relaxin signaling pathway
    K04441  P38; p38 MAP kinase
   04935 Growth hormone synthesis, secretion and action
    K04441  P38; p38 MAP kinase
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    K04441  P38; p38 MAP kinase
  09156 Nervous system
   04728 Dopaminergic synapse
    K04441  P38; p38 MAP kinase
   04723 Retrograde endocannabinoid signaling
    K04441  P38; p38 MAP kinase
   04722 Neurotrophin signaling pathway
    K04441  P38; p38 MAP kinase
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    K04441  P38; p38 MAP kinase
  09158 Development and regeneration
   04361 Axon regeneration
    K04441  P38; p38 MAP kinase
   04380 Osteoclast differentiation
    K04441  P38; p38 MAP kinase
  09149 Aging
   04212 Longevity regulating pathway - worm
    K04441  P38; p38 MAP kinase
  09159 Environmental adaptation
   04714 Thermogenesis
    K04441  P38; p38 MAP kinase
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    K04441  P38; p38 MAP kinase
   05208 Chemical carcinogenesis - reactive oxygen species
    K04441  P38; p38 MAP kinase
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    K04441  P38; p38 MAP kinase
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K04441  P38; p38 MAP kinase
   05161 Hepatitis B
    K04441  P38; p38 MAP kinase
   05171 Coronavirus disease - COVID-19
    K04441  P38; p38 MAP kinase
   05163 Human cytomegalovirus infection
    K04441  P38; p38 MAP kinase
   05167 Kaposi sarcoma-associated herpesvirus infection
    K04441  P38; p38 MAP kinase
   05169 Epstein-Barr virus infection
    K04441  P38; p38 MAP kinase
  09171 Infectious disease: bacterial
   05120 Epithelial cell signaling in Helicobacter pylori infection
    K04441  P38; p38 MAP kinase
   05130 Pathogenic Escherichia coli infection
    K04441  P38; p38 MAP kinase
   05132 Salmonella infection
    K04441  P38; p38 MAP kinase
   05131 Shigellosis
    K04441  P38; p38 MAP kinase
   05135 Yersinia infection
    K04441  P38; p38 MAP kinase
   05133 Pertussis
    K04441  P38; p38 MAP kinase
   05152 Tuberculosis
    K04441  P38; p38 MAP kinase
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    K04441  P38; p38 MAP kinase
   05140 Leishmaniasis
    K04441  P38; p38 MAP kinase
   05142 Chagas disease
    K04441  P38; p38 MAP kinase
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    K04441  P38; p38 MAP kinase
   05020 Prion disease
    K04441  P38; p38 MAP kinase
   05022 Pathways of neurodegeneration - multiple diseases
    K04441  P38; p38 MAP kinase
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    K04441  P38; p38 MAP kinase
   05418 Fluid shear stress and atherosclerosis
    K04441  P38; p38 MAP kinase
   05415 Diabetic cardiomyopathy
    K04441  P38; p38 MAP kinase
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    K04441  P38; p38 MAP kinase
   04932 Non-alcoholic fatty liver disease
    K04441  P38; p38 MAP kinase
   04933 AGE-RAGE signaling pathway in diabetic complications
    K04441  P38; p38 MAP kinase
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    K04441  P38; p38 MAP kinase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K04441  P38; p38 MAP kinase
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     K04441  P38; p38 MAP kinase
Protein kinases [BR:ko01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   K04441  P38; p38 MAP kinase
Other DBs
COG: COG0515
GO: 0004707
Genes
HSA: 1432(MAPK14) 5600(MAPK11) 5603(MAPK13) 6300(MAPK12)
PTR: 104003820(MAPK11) 450161(MAPK14) 462644(MAPK13) 747077(MAPK12)
PPS: 100980937(MAPK11) 100981268(MAPK12) 100982544(MAPK13) 100983649(MAPK14)
GGO: 101134492(MAPK12) 101134843(MAPK11) 101148438(MAPK13) 101152640(MAPK14)
PON: 100437263(MAPK12) 100438358(MAPK11) 100449269(MAPK14) 100449853(MAPK13)
NLE: 100580599(MAPK11) 100595369(MAPK13) 100600225(MAPK14)
MCC: 715745(MAPK12) 715794(MAPK11) 718976(MAPK14) 719085(MAPK13)
MCF: 101867305(MAPK12) 101867352(MAPK13) 101926770(MAPK14) 102134421(MAPK11)
MTHB: 126929437 126929447 126952773 126952775
CSAB: 103221595(MAPK13) 103221596(MAPK14) 103223551(MAPK11) 103223553(MAPK12)
CATY: 105586882(MAPK11) 105586884(MAPK12) 105592690(MAPK13) 105592727(MAPK14)
PANU: 101001103(MAPK12) 101002393(MAPK11) 101024189(MAPK14) 101024771(MAPK13)
TGE: 112622701(MAPK14) 112623522(MAPK13) 112633066(MAPK11) 112633654(MAPK12)
RRO: 104660767(MAPK12) 104660769(MAPK11) 104682867(MAPK14) 104682868(MAPK13)
RBB: 108528326(MAPK14) 108528327(MAPK13) 108539403(MAPK12) 108539422(MAPK11)
TFN: 117087120(MAPK13) 117087121(MAPK14) 117096273(MAPK12) 117096276(MAPK11)
PTEH: 111532954(MAPK12) 111542972(MAPK14) 111542973(MAPK13) 111549140(MAPK11)
CANG: 105511987(MAPK11) 105512012(MAPK12) 105514175(MAPK14) 105514260(MAPK13)
CJC: 100396611(MAPK11) 100396967(MAPK12) 100404377(MAPK14) 100405093(MAPK13)
SBQ: 101037444(MAPK14) 101040899(MAPK12) 101044137(MAPK13) 101052690(MAPK11)
CSYR: 103249454(MAPK11) 103249455(MAPK12) 103263391(MAPK14) 103263392(MAPK13)
MMUR: 105861389(MAPK13) 105861390(MAPK14) 105885016(MAPK11) 105885017(MAPK12)
LCAT: 123632869(MAPK14) 123632871(MAPK13) 123640770(MAPK12) 123640771(MAPK11)
PCOQ: 105812191(MAPK14) 105812227(MAPK13) 105813949(MAPK12) 105813961(MAPK11)
OGA: 100956269(MAPK14) 100957118(MAPK13) 100963993(MAPK11) 100964304(MAPK12)
MMU: 19094(Mapk11) 26415(Mapk13) 26416(Mapk14) 29857(Mapk12)
MCAL: 110310902(Mapk12) 110310903(Mapk11) 110312437(Mapk14) 110312562(Mapk13)
MPAH: 110334495(Mapk11) 110334829(Mapk12) 110337896(Mapk13) 110337946(Mapk14)
RNO: 29513(Mapk13) 60352(Mapk12) 689314(Mapk11) 81649(Mapk14)
MCOC: 116075101(Mapk13) 116075516(Mapk14) 116077765(Mapk11) 116077791(Mapk12)
MUN: 110546562(Mapk14) 110546585(Mapk13) 110549673(Mapk12) 110549680(Mapk11)
CGE: 100689104(Mapk14) 100754042(Mapk12) 100759172(Mapk11) 100763519(Mapk13)
MAUA: 101824303(Mapk14) 101824910(Mapk13) 101826592(Mapk11) 101833914(Mapk12)
PLEU: 114693019(Mapk12) 114693020(Mapk11) 114706162(Mapk13) 114706165(Mapk14)
MORG: 121435212(Mapk14) 121435574(Mapk13) 121461212(Mapk12) 121461365(Mapk11)
AAMP: 119822988(Mapk11) 119823276(Mapk12) 119823839(Mapk13) 119823840(Mapk14)
NGI: 103735473(Mapk12) 103735474(Mapk11) 103739659(Mapk13) 103739660(Mapk14)
HGL: 101705370(Mapk11) 101706002(Mapk12) 101715692(Mapk13) 106007524(Mapk14)
CPOC: 100723285(Mapk14) 100724974(Mapk11) 100729280(Mapk13)
CCAN: 109689849(Mapk14) 109689865(Mapk13) 109697389(Mapk11) 109697648(Mapk12)
DORD: 105992729 105995746(Mapk13) 105995771(Mapk14)
DSP: 122111502(Mapk13) 122111503(Mapk14) 122123649(Mapk12)
OPI: 101524339(MAPK11) 101524571(MAPK12) 101525120(MAPK14) 101525684(MAPK13)
TUP: 102481241(MAPK13) 102487603(MAPK11) 102495693(MAPK14) 102501733(MAPK12)
GVR: 103587477(MAPK12) 103587478(MAPK11) 103607428(MAPK13) 103607442(MAPK14)
CFA: 403856(MAPK14) 607019(MAPK11) 607023(MAPK12) 612821(MAPK13)
CLUD: 112641479(MAPK14) 112641481(MAPK13) 112665560(MAPK11) 112665622(MAPK12)
VVP: 112913931(MAPK14) 112913932(MAPK13) 112935862(MAPK12) 112935863(MAPK11)
VLG: 121482054(MAPK14) 121485950(MAPK13) 121491672(MAPK11) 121491673(MAPK12)
AML: 100465223(MAPK13) 100465476(MAPK14) 100480235(MAPK12) 100480483(MAPK11)
UMR: 103665451(MAPK14) 103665538(MAPK13) 103674115(MAPK12)
UAH: 113241613(MAPK11) 113241615(MAPK12) 113243852(MAPK14) 113243854(MAPK13)
UAR: 123776209(MAPK13) 123776212(MAPK14) 123803776(MAPK12) 123803793(MAPK11)
MPUF: 101684009(MAPK14) 101684873(MAPK13) 101686271(MAPK12) 101692143(MAPK11)
ORO: 101377143(MAPK13) 101377430(MAPK14) 101382259(MAPK11) 101382558(MAPK12)
EJU: 114218424(MAPK12) 114218476(MAPK11) 114222054(MAPK13) 114222247(MAPK14)
ZCA: 113921975(MAPK12) 113923113(MAPK11) 113926549(MAPK14) 113927499(MAPK13)
MLX: 117997742(MAPK11) 117997743(MAPK12) 118001095(MAPK13) 118001265(MAPK14)
NSU: 110575614(MAPK13) 110575674(MAPK14) 110578302(MAPK12) 110578303(MAPK11)
LWW: 102725695(MAPK12) 102738377 102746987(MAPK14) 115942902(MAPK13)
FCA: 101091536(MAPK13) 101101135(MAPK14) 105260786(MAPK11) 111556320(MAPK12)
PYU: 121024845(MAPK11) 121029354(MAPK14) 121029356(MAPK13) 121040120(MAPK12)
PBG: 122472987(MAPK12) 122472989(MAPK11) 122490348(MAPK14) 122490350(MAPK13)
PTG: 102960306(MAPK12) 102960590(MAPK11) 102968191(MAPK13) 102968482(MAPK14)
PPAD: 109265257(MAPK11) 109265767 109271512(MAPK14) 109271515(MAPK13)
AJU: 106972759(MAPK14) 106972806(MAPK13) 106987636(MAPK12) 106987637(MAPK11)
HHV: 120233796(MAPK14) 120233829(MAPK13) 120234701(MAPK12) 120235253(MAPK11)
BTA: 512943(MAPK12) 534492(MAPK14) 535327(MAPK13) 618906(MAPK11)
BOM: 102271030(MAPK13) 102271320(MAPK14) 102285848(MAPK12) 106701244(MAPK11)
BIU: 109577010(MAPK14) 109577419(MAPK13)
BBUB: 102397149(MAPK14) 102397694(MAPK13) 102409665(MAPK12) 102410439(MAPK11)
BBIS: 104981967(MAPK12) 104981977(MAPK11) 104994938(MAPK14) 104994939(MAPK13)
CHX: 100860996(MAPK13) 102180926(MAPK12) 102184510(MAPK11) 102189174(MAPK14)
OAS: 100194428(MAPK13) 100217411(MAPK14) 101115956(MAPK12) 101116223(MAPK11)
ODA: 120857807(MAPK12) 120857808(MAPK11) 120870210(MAPK13) 120870211(MAPK14)
CCAD: 122423529(MAPK12) 122423531(MAPK11) 122429123(MAPK14) 122429963(MAPK13)
SSC: 100155841(MAPK13) 100156630(MAPK14) 110260605(MAPK11) 574062(MAPK12)
CFR: 102511078(MAPK14) 102511298(MAPK13) 102516847(MAPK12) 102519781(MAPK11)
CBAI: 105064175(MAPK13) 105064176(MAPK14) 105070806(MAPK12) 105070807(MAPK11)
CDK: 105090355(MAPK11) 105090356(MAPK12) 105101337(MAPK13) 105101338(MAPK14)
VPC: 102525219(MAPK12) 102531650(MAPK11) 102540698(MAPK14) 102541290(MAPK13)
BACU: 102999798 103002378(MAPK13) 103008537(MAPK14) 103009947(MAPK12)
LVE: 103077530(MAPK12) 103078049(MAPK14) 103078710(MAPK13) 103083209(MAPK11)
OOR: 101269212(MAPK13) 101269458(MAPK14) 101287579(MAPK12) 101287833(MAPK11)
DLE: 111178736(MAPK14) 111178738(MAPK13) 111186361(MAPK12) 111186364(MAPK11)
PCAD: 102977531(MAPK12) 102977994(MAPK11) 102989111(MAPK14) 102990302(MAPK13)
PSIU: 116760605(MAPK12) 116760782(MAPK11) 116762796(MAPK13) 116762798(MAPK14)
ECB: 100056239(MAPK12) 100056278(MAPK11) 100063532(MAPK14) 106782258(MAPK13)
EPZ: 103559485(MAPK12) 103559491(MAPK11) 103563198(MAPK13) 103565534(MAPK14)
EAI: 106824547(MAPK14) 106824582(MAPK13) 106846005(MAPK12) 106846006(MAPK11)
MYB: 102248097(MAPK14) 102254628(MAPK12) 102254920(MAPK11) 106723559(MAPK13)
MYD: 102755728(MAPK14) 102756012(MAPK13) 102770021(MAPK12) 102770309(MAPK11)
MMYO: 118657384(MAPK11) 118660246(MAPK13) 118660247(MAPK14)
MLF: 102437934(MAPK14) 102438914
MNA: 107536041(MAPK12) 107536051(MAPK11) 107545565(MAPK13) 107545613(MAPK14)
PKL: 118705126(MAPK13) 118705127(MAPK14) 118714740(MAPK12) 118714741(MAPK11)
HAI: 109395979(MAPK14) 109395980(MAPK13) 109396629(MAPK12) 109396630(MAPK11)
DRO: 112302047(MAPK14) 112302140(MAPK13) 112321896(MAPK12) 112322057
SHON: 118988883(MAPK12) 118988898(MAPK11) 118998971(MAPK13) 118998973(MAPK14)
AJM: 119050071(MAPK14) 119050081(MAPK13) 119060490(MAPK12) 119060539(MAPK11)
PDIC: 114493876(MAPK14) 114493878(MAPK13) 114513098(MAPK12) 114513304(MAPK11)
PHAS: 123816206(MAPK12) 123816247(MAPK11) 123822258(MAPK13) 123822259(MAPK14)
MMF: 118621004(MAPK13) 118621005(MAPK14) 118641186(MAPK12) 118641187(MAPK11)
RFQ: 117016461(MAPK14) 117020595(MAPK13) 117029085(MAPK11) 117029232(MAPK12)
PALE: 102877720(MAPK13) 102888602(MAPK11) 102888845(MAPK12) 102895900(MAPK14)
PGIG: 120597571(MAPK13) 120597692(MAPK14) 120602825(MAPK12) 120602826(MAPK11)
PVP: 105301035(MAPK14) 105301036(MAPK13) 105308283
RAY: 107497883(MAPK14) 107497895(MAPK13) 107500264(MAPK12) 107500274(MAPK11)
MJV: 108394635 108394636(MAPK14) 108395598(MAPK12) 108395610(MAPK11)
TOD: 119247132(MAPK12) 119247133(MAPK11) 119250929 119252387(MAPK14) 119252388(MAPK13)
SARA: 101536977(MAPK14) 101537598(MAPK13) 101545321(MAPK12) 101554044(MAPK11)
LAV: 100656926(MAPK13) 100661039(MAPK12) 100673331(MAPK14)
ETF: 101653430(MAPK11) 101653940(MAPK12) 101656204(MAPK14) 101657745(MAPK13)
DNM: 101415496(MAPK12) 101416217(MAPK11) 101425795(MAPK14) 101426841(MAPK13)
MDO: 100010279(MAPK12) 100010891(MAPK11) 100026324(MAPK14) 100028821(MAPK13)
GAS: 123243860(MAPK13) 123245414(MAPK14) 123248655(MAPK11) 123250672(MAPK12)
SHR: 100925013(MAPK14) 100925447(MAPK13) 100928729(MAPK12) 100928990(MAPK11)
PCW: 110205920(MAPK11) 110205921(MAPK12) 110217326(MAPK13) 110217327(MAPK14)
OAA: 100078507(MAPK13) 100091330(MAPK11) 100092264(MAPK14)
GGA: 417739(MAPK11) 421183(MAPK14) 769763(MAPK12) 771145(MAPK13)
PCOC: 116238776(MAPK14) 116238777(MAPK13) 116243637(MAPK12) 116243644(MAPK11)
MGP: 100540259(MAPK12) 100540416(MAPK11) 100546983(MAPK13)
CJO: 107308531 107308592(MAPK11) 107324607(MAPK13) 107324616(MAPK14)
NMEL: 110388127(MAPK13) 110388128(MAPK14) 110392503 110392504
APLA: 101792057(MAPK11) 101793591(MAPK12) 101802116(MAPK13) 101805023(MAPK14)
ACYG: 106040461(MAPK12) 106040490(MAPK11) 106046149(MAPK14) 106046150(MAPK13)
AFUL: 116489834(MAPK11) 116489843(MAPK12) 116498684(MAPK14)
TGU: 100225101(MAPK11) 100227852(MAPK14) 100227993(MAPK12) 105758887(MAPK13)
LSR: 110473464(MAPK13) 110473465(MAPK14) 110484504(MAPK11) 110484512(MAPK12)
SCAN: 103813488(MAPK11) 103813699(MAPK12) 103823281(MAPK13) 103823282(MAPK14)
PMOA: 120495919(MAPK13) 120495921 120510759(MAPK12) 120510784(MAPK11)
OTC: 121336326(MAPK11) 121336380(MAPK12) 121348027(MAPK14) 121348029(MAPK13)
PRUF: 121353388(MAPK13) 121353401(MAPK14) 121355781(MAPK11)
GFR: 102038787(MAPK11) 102042160(MAPK13) 102043521(MAPK12) 102044158(MAPK14)
FAB: 101807358(MAPK12) 101814783(MAPK11) 101817434(MAPK13) 101819980(MAPK14)
PHI: 102109820(MAPK11) 102110009(MAPK12) 102110807 102111004
PMAJ: 107204408(MAPK12) 107204409(MAPK11) 107214801(MAPK13) 107214802(MAPK14)
CCAE: 111922987(MAPK11) 111923053(MAPK12) 111939795(MAPK13) 111939796(MAPK14)
CCW: 104686831(MAPK11) 104686906(MAPK12) 104692399(MAPK14) 104692401(MAPK13)
ETL: 114062949(MAPK11) 114062955(MAPK12) 114065754(MAPK13) 114065755(MAPK14)
ZAB: 102063173(MAPK12) 102063357(MAPK11) 102067210(MAPK14) 102067622(MAPK13)
ACHL: 103797444(MAPK13) 103797445(MAPK14) 103807808(MAPK12) 103808070
FPG: 101920170(MAPK12) 101920353(MAPK11) 101921635(MAPK14) 101922433(MAPK13)
FCH: 102051874(MAPK12) 102052038(MAPK11) 102054359(MAPK13) 102059377(MAPK14)
EGZ: 104125670(MAPK12) 104125693(MAPK11) 104125710(MAPK13) 104125751(MAPK14)
NNI: 104010338(MAPK13) 104010702(MAPK11) 104010773(MAPK12) 104013235(MAPK14)
PLET: 104618194 104618865 104618866(MAPK14) 104628347(MAPK11)
PCRI: 104025822 104027053(MAPK12) 104038309(MAPK13) 104038310(MAPK14)
PCAO: 104045500 104048216(MAPK14) 104051094(MAPK13) 104053513
ACUN: 113488967 113488974 113491236(MAPK12) 113491286(MAPK11)
TALA: 104361916(MAPK13) 104363966(MAPK11) 104367240(MAPK14) 104367347(MAPK12)
PADL: 103923636(MAPK12) 103923637(MAPK11) 103925940(MAPK13) 103925963(MAPK14)
AFOR: 103893653(MAPK13) 103893654(MAPK14) 103905253(MAPK12) 103905254(MAPK11)
ACHC: 115334823(MAPK13) 115334828 115341623(MAPK11) 115341838(MAPK12)
HLE: 104840382(MAPK11) 104840411(MAPK12) 104842349(MAPK14) 104842350(MAPK13)
CCRI: 104158274(MAPK13) 104158275(MAPK14) 104161750(MAPK12) 104166757
CSTI: 104553633(MAPK12) 104553743(MAPK13) 104553744(MAPK14) 104561972(MAPK11)
EHS: 104503098(MAPK12) 104503884 104506264 104511199(MAPK13)
CMAC: 104476042(MAPK11) 104481863(MAPK12) 104484690(MAPK13) 104484691(MAPK14)
FGA: 104069378 104071175(MAPK14) 104071309 104082925(MAPK13)
GSTE: 104250287 104251557(MAPK14) 104251718(MAPK13) 104254581(MAPK12)
LDI: 104343723(MAPK13) 104343731(MAPK14) 104345286(MAPK12) 104350868
MNB: 103770767(MAPK13) 103773410(MAPK11) 103773811(MAPK12) 103780956(MAPK14)
OHA: 104330023(MAPK11) 104330049(MAPK12) 104336307 104336312(MAPK14)
DPUB: 104297424(MAPK12) 104297425(MAPK11) 104302149(MAPK14) 104302150(MAPK13)
CPEA: 104387234(MAPK14) 104387330 104393872(MAPK11) 104393877(MAPK12)
CVF: 104285227(MAPK11) 104285259(MAPK12) 104292348(MAPK13) 104292365(MAPK14)
CUCA: 104055295(MAPK12) 104055296(MAPK11) 104065107(MAPK13) 104065110(MAPK14)
BRHI: 104489576(MAPK13) 104491252(MAPK12) 104492731 104500087
AAM: 106487858(MAPK13) 106487877(MAPK14) 106495922(MAPK12) 106495935(MAPK11)
AROW: 112961437(MAPK13) 112961439(MAPK14) 112973525(MAPK11) 112973531(MAPK12)
NPD: 112959234(MAPK13) 112959267(MAPK14) 112959724(MAPK11) 112959727(MAPK12)
TGT: 104564316 104564324(MAPK14) 104580471(MAPK11) 104580476(MAPK12)
DNE: 112990255(MAPK13) 112990256(MAPK14) 112990935(MAPK12) 112990942(MAPK11)
SCAM: 104139401(MAPK13) 104139403(MAPK14) 104151524(MAPK11) 104151532(MAPK12)
ASN: 102374196(MAPK12) 102375835(MAPK11) 102375954(MAPK13) 102376541(MAPK14)
AMJ: 102565670(MAPK14) 102571177(MAPK11) 102571419(MAPK12) 106736779(MAPK13)
CPOO: 109315663(MAPK12) 109315664(MAPK11) 109317454(MAPK14) 109317501(MAPK13)
GGN: 109292044(MAPK11) 109292045(MAPK12) 109295121(MAPK14) 109295122(MAPK13)
PSS: 102448785(MAPK14) 102455939(MAPK13) 102462429(MAPK11) 102462672(MAPK12)
CMY: 102934859(MAPK14) 102938087(MAPK11) 102940215(MAPK12) 102941338(MAPK13)
CPIC: 101946632(MAPK13) 101948637(MAPK14) 101952286(MAPK12) 101952546(MAPK11)
TST: 117875889(MAPK13) 117875891(MAPK14) 117876012(MAPK12) 117876024(MAPK11)
CABI: 116818466(MAPK12) 116818471(MAPK11) 116839140(MAPK14) 116839153(MAPK13)
MRV: 120389525(MAPK11) 120389611(MAPK12) 120403531(MAPK14) 120404342(MAPK13)
ACS: 100563538(mapk12) 100563731(mapk11) 100567479(mapk13) 100567676(mapk14)
PVT: 110079793(MAPK14) 110079814(MAPK13) 110089644 110089645
SUND: 121928200(MAPK14) 121929971(MAPK13) 121930696(MAPK11) 121930697(MAPK12)
PBI: 103053438(MAPK14) 103053997(MAPK13) 103063187(MAPK12) 103063888(MAPK11)
PMUR: 107286325(MAPK12) 107286326(MAPK11) 107292823(MAPK14) 107292825(MAPK13)
CTIG: 120298965(MAPK13) 120298976(MAPK14) 120306032(MAPK11) 120306038(MAPK12)
TSR: 106539166(MAPK14) 106539167(MAPK13) 106539876(MAPK12) 106556039
PGUT: 117664010(MAPK13) 117664013(MAPK14) 117667650(MAPK12) 117667674(MAPK11)
VKO: 123020010(MAPK11) 123020058(MAPK12)
PMUA: 114599205(MAPK14) 114599208(MAPK13) 114605047(MAPK11) 114605285(MAPK12)
ZVI: 118088107(MAPK14) 118088847(MAPK13) 118090805(MAPK11) 118091073(MAPK12)
GJA: 107110949(MAPK12) 107110955(MAPK11) 107110975 107119112(MAPK13)
STOW: 125433598(MAPK14) 125433664(MAPK13) 125434206(MAPK11)
XLA: 100329215(mapk11.L) 108708144 108711159 108715909 379992(mapk14.S) 398592(mapk12.S) 494669(mapk11.S) 735153(XB956263.L)
XTR: 100101766(mapk11) 100144715(mapk13) 100145045 448296(mapk14) 549834(mapk12)
NPR: 108787378 108788240 108804838(MAPK12) 108804839(MAPK11)
RTEM: 120927297 120931826(MAPK12) 120931827(MAPK11) 120945156
BBUF: 120978482 120982071(MAPK11) 120982080(MAPK12) 120995148
DRE: 100002318(mapk13) 266756(mapk14b) 30681(mapk12a) 415185(mapk11) 557810(mapk12b) 562552(zgc:171775) 65237(mapk14a)
PPRM: 120462104(mapk12a) 120469059(mapk14a) 120473428(mapk14b) 120474753(mapk13) 120476626(mapk12b) 120476628(mapk11)
MAMB: 125246180(mapk12b) 125246181(mapk11) 125254075(mapk12a) 125257055(mapk14b) 125260456(zgc:171775) 125279668(mapk13) 125279793(mapk14a)
IPU: 108254806(mapk14b) 108264559(mapk12a) 108265696(mapk13) 108265726(mapk14a) 108276094(zgc:171775) 108279456(mapk11) 108279513(mapk12b) 124627952
SMEO: 124396074(mapk12a) 124399179(zgc:171775) 124399896(mapk13) 124399991(mapk14a) 124400837(mapk12b) 124400838(mapk11) 124402156(mapk14b)
TFD: 113642051(zgc:171775) 113645471(mapk13) 113647229(mapk11) 113647286(mapk12b) 113652784(mapk12a) 113656309(mapk14a) 113661912(mapk14b)
ELY: 117248907(mapk12b) 117249233(mapk11) 117253792(mapk12a) 117257217(mapk14b) 117258336(mapk14a) 117258429(zgc:171775) 117258644(mapk13)
EFO: 125882572 125882761(mapk11) 125886996(mapk12a) 125891336(mapk14a) 125891457(zgc:171775) 125891603(mapk13) 125897587(mapk14b)
PLEP: 121946583(mapk14a) 121946587(mapk13) 121947552(zgc:171775) 121950748(mapk12a) 121952837(mapk14b) 121961086(mapk11) 121961232(mapk12b)
SLUC: 116038647(mapk12a) 116040750(mapk14a) 116040793(zgc:171775) 116040932(mapk13) 116054782(mapk11) 116054783 116067450(mapk14b)
ECRA: 117938704(mapk12b) 117938858(mapk11) 117943738(mapk14b) 117947167(mapk14a) 117947245(zgc:171775) 117947999(mapk13) 117948650(mapk12a)
GAT: 120809364 120812710 120817131(mapk11) 120817132(mapk12b) 120828911(mapk14a) 120829044(zgc:171775) 120829497(mapk13) 120835277(mapk14b)
PPUG: 119196584(mapk12a) 119210172(mapk11) 119210173(mapk12b) 119221846(mapk14a) 119222286(zgc:171775) 119222347(mapk13) 119229842(mapk14b)
MSAM: 119886184(mapk14b) 119891584(zgc:171775) 119905572(mapk14a) 119906000(mapk13) 119915355(mapk12a) 119918284(mapk11) 119918532
CUD: 121504460(mapk14b) 121514771(mapk12a) 121517191(mapk14a) 121517463(zgc:171775) 121517916(mapk13)
ALAT: 119021965(mapk14b) 119023050(mapk14a) 119023341(mapk13) 119023513(zgc:171775) 119023727(mapk12a) 119032335(mapk12b) 119032659(mapk11)
OAU: 116309701(mapk14a) 116312555(mapk12a) 116315613(zgc:171775) 116317384(mapk13) 116323199(mapk11) 116323203(mapk12b) 116326502(mapk14b)
OML: 112139315(mapk14b) 112152089(mapk12a) 112158679(zgc:171775) 112158855(mapk14a) 112159424(mapk13) 112160268(mapk12b) 112160269(mapk11)
GAF: 122826436(zgc:171775) 122826508(mapk11) 122826510 122827801(mapk13) 122834749(mapk14b) 122835819(mapk12a) 122837287(mapk14a)
CTUL: 119771643(zgc:171775) 119782237(mapk14a) 119786493(mapk13) 119789373(mapk12b) 119789378(mapk11) 119791743(mapk14b) 119796794(mapk12a)
GMU: 124857113(mapk14b) 124858438(mapk12a) 124868188(mapk14a) 124871744(zgc:171775) 124872081(mapk13) 124882732 124882947(mapk11)
KMR: 108233125(mapk13) 108233159(zgc:171775) 108237567(mapk12a) 108244594(mapk14a) 108246862(mapk14b) 108251045(mapk12b) 108251047(mapk11)
NWH: 119411666(mapk14b) 119415605(mapk12a) 119417639(mapk14a) 119417725(mapk13) 119417736(zgc:171775) 119428581(mapk11) 119428582(mapk12b)
MCEP: 124997305(mapk14a) 124999916(mapk11) 124999917 125006555(mapk14b) 125010906(zgc:171775) 125015404(mapk12a) 125019204(mapk13)
SSEN: 122766959(mapk12b) 122766961(mapk11) 122767630(mapk14b) 122775763(mapk12a) 122777114(mapk14a) 122777639(mapk13) 122777856(zgc:171775)
HHIP: 117757226(mapk11) 117757227(mapk12b) 117761402(mapk14b) 117763532(mapk12a) 117764155(mapk13) 117764159(mapk14a) 117764912(zgc:171775)
HSP: 118101535(mapk11) 118101536(mapk12b) 118104855(mapk14b) 118109156(mapk12a) 118110753(mapk14a) 118111319(mapk13) 118111462(zgc:171775)
LCF: 108875352(mapk12a) 108876452(mapk14a) 108882620(mapk13) 108882672(zgc:171775) 108884069 108901376 108901401(mapk11)
XGL: 120783206(mapk14b) 120792797(mapk12a) 120798605(mapk11) 120800214 120803801(mapk13) 120803829(zgc:171775) 120803885(mapk14a)
BSPL: 114855788(mapk14b) 114857567(mapk12a) 114858494(mapk13) 114859152(mapk14a) 114859326(zgc:171775) 114861856 114861857(mapk11)
PSEX: 120526229(mapk14b) 120526230(mapk13) 120539589(mapk11) 120539590(mapk12a) 120540369(zgc:171775)
LCM: 102354316(MAPK11) 102354774(MAPK12) 102358042(MAPK14)
BBEL: 109486492
CIN: 778927(p38)
SCLV: 120340616
APLC: 110982110
AJC: 117108729
SKO: 100313652
DME: Dmel_CG33338(p38c) Dmel_CG5475(p38a) Dmel_CG7393(p38b)
DSI: Dsimw501_GD18318(Dsim_GD18318) Dsimw501_GD18319(Dsim_GD18319) Dsimw501_GD23919(Dsim_GD23919)
MDE: 101898223
HIS: 119651179
ACOZ: 120955183
AARA: 120905032
ASTE: 118504036
AAG: 5570571
CPII: 120417568
CNS: 116338437
BCOO: 119082091
AME: 411915
ACER: 107992603
ALAB: 122717314
BIM: 100743495
BBIF: 117216780
BVK: 117232844
BVAN: 117163900
BTER: 100648398
BPYO: 122570210
CCAL: 108632272
OBB: 114879935
MGEN: 117222146
NMEA: 116434605
CGIG: 122400271
SOC: 105200628
MPHA: 105835049
AEC: 105152195
ACEP: 105622634
PBAR: 105432414
VEM: 105557809
HST: 105182275
DQU: 106751692
CFO: 105252862
FEX: 115240435
LHU: 105672601
PGC: 109859454
OBO: 105275402
PCF: 106786367
PFUC: 122520648
VPS: 122626919
NVI: 100114440(P38mapk)
CSOL: 105363152
TPRE: 106654238
MDL: 103578144
CGLO: 123262958
FAS: 105265276
DAM: 107043062
AGIF: 122852819
CINS: 118068437
LHT: 122510268
CCIN: 107268603
TCA: 660539
DPA: 109540885
SOY: 115876777
ATD: 109600802
CSET: 123321622
AGB: 108912416
LDC: 111503651
NVL: 108568750
APLN: 108737316
PPYR: 116165879
OTU: 111425152
BMOR: 692545(P38mapk)
BMAN: 114246249
MSEX: 115448643
BANY: 112044245
NIQ: 126772588
PMAC: 106709262
PPOT: 106099328
PXU: 106124912
PRAP: 111003831
PBX: 123715895
PNAP: 125057354
ZCE: 119829487
CCRC: 123696220
HAW: 110378533
HZE: 124634272
TNL: 113501942
SLIU: 111353439
OFU: 114351925
PXY: 105391720
DNX: 107162001
AGS: 114125078
RMD: 113548140
BTAB: 109033725
DCI: 103518913
CLEC: 106663306
HHAL: 106677951
NLU: 111052110
FOC: 113202661
ZNE: 110841257
CSEC: 111868512
SGRE: 126365804
FCD: 110848493
DMK: 116919171
DPZ: 124343290
PVM: 113815719
PCHN: 125047533
HAME: 121868235
PCLA: 123771879
PTRU: 123498536
HAZT: 108669900
EAF: 111698973
LSM: 121119022
PPOI: 119091420
DSV: 119431015
RSAN: 119378333
RMP: 119162994
VDE: 111249745
VJA: 111265847
TUT: 107371307
DPTE: 113794280
DFR: 124490825
PTEP: 107449390
SDM: 118186295
CEL: CELE_B0218.3(pmk-1) CELE_F42G8.3(pmk-2) CELE_F42G8.4(pmk-3)
CBR: CBG_01553(Cbr-pmk-3) CBG_01554(Cbr-pmk-2) CBG_01555(Cbr-pmk-1)
BMY: BM_BM1712(Bma-pmk-1) BM_BM4029(Bma-pmk-3)
TSP: Tsp_03128
BGT: 106074771
CRG: 105347124
MYI: 110452642
PMAX: 117331943
MMER: 123529465
NVE: 5519091
EPA: 110236778
ATEN: 116289446
ADF: 107339756
AMIL: 114965938
PDAM: 113671938
SPIS: 111324228
XEN: 124434533
QSU: 112036994
SCE: YLR113W(HOG1)
SEUB: DI49_3638
ERC: Ecym_4266
KMX: KLMA_40175(HOG1)
NCS: NCAS_0C03380(NCAS0C03380)
NDI: NDAI_0G02700(NDAI0G02700)
TPF: TPHA_0A01630(TPHA0A01630)
TBL: TBLA_0H01330(TBLA0H01330)
TDL: TDEL_0F04290(TDEL0F04290)
KAF: KAFR_0B02980(KAFR0B02980)
KNG: KNAG_0G02300(KNAG0G02300)
CAL: CAALFM_C203330CA(HOG1)
CDU: CD36_18080(HOG1)
SLB: AWJ20_3640(HOG1)
BNN: FOA43_002402(HOG1)
BBRX: BRETT_000835(HOG1)
NCR: NCU07024(os-2)
NTE: NEUTE1DRAFT121521(NEUTE1DRAFT_121521)
SMP: SMAC_09127(putative os2)
MGR: MGG_01822
SSCK: SPSK_07444
TRE: TRIREDRAFT_45018(tmk3)
MAW: MAC_08084
MAJ: MAA_05126
CMT: CCM_04200
BFU: BCIN_15g03580(Bcsak1)
MBE: MBM_02950
ANG: ANI_1_1404164(An18g05270) ANI_1_492064(An07g03980) ANI_1_826074(An08g05850)
ALUC: AKAW2_11794S(HOG1_1) AKAW2_30494A(HOG1_2) AKAW2_31095S(HOG1_3)
ACHE: ACHE_30405S(HOG1_1) ACHE_40322S(HOG1_4)
APUU: APUU_50768A(HOG1_1) APUU_60789S(HOG1_2) APUU_70955A(HOG1_3)
ABE: ARB_01456
TVE: TRV_02393
PTE: PTT_10964
BSC: COCSADRAFT_94680(HOG1)
ZTR: MYCGRDRAFT_76502(MgHog1)
SPO: SPAC24B11.06c(sty1)
CNE: CNC06590
CNB: CNBC0610
TASA: A1Q1_05022
ABP: AGABI1DRAFT22411(AGABI1DRAFT_22411)
ABV: AGABI2DRAFT41003(AGABI2DRAFT_41003)
SCM: SCHCO_02175896(SCHCODRAFT_02175896)
MGL: MGL_0949
MRT: MRET_3200
 » show all
Reference
PMID:9744864
  Authors
O'Rourke SM, Herskowitz I
  Title
The Hog1 MAPK prevents cross talk between the HOG and pheromone response MAPK pathways in Saccharomyces cerevisiae.
  Journal
Genes Dev 12:2874-86 (1998)
DOI:10.1101/gad.12.18.2874
  Sequence
[sce:YLR113W]
Reference
PMID:8633070
  Authors
Lechner C, Zahalka MA, Giot JF, Moller NP, Ullrich A
  Title
ERK6, a mitogen-activated protein kinase involved in C2C12 myoblast differentiation.
  Journal
Proc Natl Acad Sci U S A 93:4355-9 (1996)
DOI:10.1073/pnas.93.9.4355
  Sequence
[hsa:6300]
LinkDB

KEGG   ORTHOLOGY: K04440
Entry
K04440                      KO                                     
Symbol
JNK
Name
mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
Pathway
map01522  Endocrine resistance
map04010  MAPK signaling pathway
map04012  ErbB signaling pathway
map04013  MAPK signaling pathway - fly
map04014  Ras signaling pathway
map04024  cAMP signaling pathway
map04068  FoxO signaling pathway
map04071  Sphingolipid signaling pathway
map04137  Mitophagy - animal
map04140  Autophagy - animal
map04141  Protein processing in endoplasmic reticulum
map04210  Apoptosis
map04212  Longevity regulating pathway - worm
map04214  Apoptosis - fly
map04215  Apoptosis - multiple species
map04217  Necroptosis
map04310  Wnt signaling pathway
map04361  Axon regeneration
map04380  Osteoclast differentiation
map04391  Hippo signaling pathway - fly
map04510  Focal adhesion
map04530  Tight junction
map04620  Toll-like receptor signaling pathway
map04621  NOD-like receptor signaling pathway
map04622  RIG-I-like receptor signaling pathway
map04624  Toll and Imd signaling pathway
map04625  C-type lectin receptor signaling pathway
map04657  IL-17 signaling pathway
map04658  Th1 and Th2 cell differentiation
map04659  Th17 cell differentiation
map04660  T cell receptor signaling pathway
map04664  Fc epsilon RI signaling pathway
map04668  TNF signaling pathway
map04722  Neurotrophin signaling pathway
map04723  Retrograde endocannabinoid signaling
map04728  Dopaminergic synapse
map04750  Inflammatory mediator regulation of TRP channels
map04910  Insulin signaling pathway
map04912  GnRH signaling pathway
map04914  Progesterone-mediated oocyte maturation
map04917  Prolactin signaling pathway
map04920  Adipocytokine signaling pathway
map04926  Relaxin signaling pathway
map04930  Type II diabetes mellitus
map04931  Insulin resistance
map04932  Non-alcoholic fatty liver disease
map04933  AGE-RAGE signaling pathway in diabetic complications
map04935  Growth hormone synthesis, secretion and action
map04936  Alcoholic liver disease
map05010  Alzheimer disease
map05012  Parkinson disease
map05016  Huntington disease
map05017  Spinocerebellar ataxia
map05020  Prion disease
map05022  Pathways of neurodegeneration - multiple diseases
map05120  Epithelial cell signaling in Helicobacter pylori infection
map05130  Pathogenic Escherichia coli infection
map05131  Shigellosis
map05132  Salmonella infection
map05133  Pertussis
map05135  Yersinia infection
map05142  Chagas disease
map05145  Toxoplasmosis
map05152  Tuberculosis
map05161  Hepatitis B
map05162  Measles
map05166  Human T-cell leukemia virus 1 infection
map05167  Kaposi sarcoma-associated herpesvirus infection
map05169  Epstein-Barr virus infection
map05170  Human immunodeficiency virus 1 infection
map05171  Coronavirus disease - COVID-19
map05200  Pathways in cancer
map05208  Chemical carcinogenesis - reactive oxygen species
map05210  Colorectal cancer
map05212  Pancreatic cancer
map05231  Choline metabolism in cancer
map05415  Diabetic cardiomyopathy
map05417  Lipid and atherosclerosis
map05418  Fluid shear stress and atherosclerosis
Disease
H01813  Lennox-Gastaut syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
   04013 MAPK signaling pathway - fly
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
   04012 ErbB signaling pathway
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
   04014 Ras signaling pathway
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
   04310 Wnt signaling pathway
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
   04391 Hippo signaling pathway - fly
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
   04668 TNF signaling pathway
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
   04068 FoxO signaling pathway
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
   04071 Sphingolipid signaling pathway
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
   04024 cAMP signaling pathway
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
   04137 Mitophagy - animal
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
  09143 Cell growth and death
   04210 Apoptosis
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
   04214 Apoptosis - fly
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
   04215 Apoptosis - multiple species
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
   04217 Necroptosis
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
   04530 Tight junction
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
   04624 Toll and Imd signaling pathway
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
   04621 NOD-like receptor signaling pathway
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
   04622 RIG-I-like receptor signaling pathway
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
   04625 C-type lectin receptor signaling pathway
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
   04660 T cell receptor signaling pathway
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
   04658 Th1 and Th2 cell differentiation
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
   04659 Th17 cell differentiation
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
   04657 IL-17 signaling pathway
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
   04664 Fc epsilon RI signaling pathway
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
  09152 Endocrine system
   04910 Insulin signaling pathway
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
   04920 Adipocytokine signaling pathway
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
   04912 GnRH signaling pathway
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
   04914 Progesterone-mediated oocyte maturation
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
   04917 Prolactin signaling pathway
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
   04926 Relaxin signaling pathway
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
   04935 Growth hormone synthesis, secretion and action
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
  09156 Nervous system
   04728 Dopaminergic synapse
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
   04723 Retrograde endocannabinoid signaling
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
   04722 Neurotrophin signaling pathway
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
  09158 Development and regeneration
   04361 Axon regeneration
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
   04380 Osteoclast differentiation
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
  09149 Aging
   04212 Longevity regulating pathway - worm
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
   05208 Chemical carcinogenesis - reactive oxygen species
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
   05231 Choline metabolism in cancer
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
  09162 Cancer: specific types
   05210 Colorectal cancer
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
   05212 Pancreatic cancer
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
   05170 Human immunodeficiency virus 1 infection
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
   05161 Hepatitis B
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
   05171 Coronavirus disease - COVID-19
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
   05162 Measles
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
   05167 Kaposi sarcoma-associated herpesvirus infection
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
   05169 Epstein-Barr virus infection
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
  09171 Infectious disease: bacterial
   05120 Epithelial cell signaling in Helicobacter pylori infection
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
   05130 Pathogenic Escherichia coli infection
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
   05132 Salmonella infection
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
   05131 Shigellosis
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
   05135 Yersinia infection
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
   05133 Pertussis
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
   05152 Tuberculosis
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
   05142 Chagas disease
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
   05012 Parkinson disease
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
   05016 Huntington disease
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
   05017 Spinocerebellar ataxia
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
   05020 Prion disease
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
   05022 Pathways of neurodegeneration - multiple diseases
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
   05418 Fluid shear stress and atherosclerosis
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
   05415 Diabetic cardiomyopathy
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
   04936 Alcoholic liver disease
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
   04932 Non-alcoholic fatty liver disease
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
   04931 Insulin resistance
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
   04933 AGE-RAGE signaling pathway in diabetic complications
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
Protein kinases [BR:ko01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   K04440  JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase)
Other DBs
GO: 0004705
Genes
HSA: 5599(MAPK8) 5601(MAPK9) 5602(MAPK10)
PTR: 450445(MAPK8) 461358(MAPK10) 462336(MAPK9)
PPS: 100982480(MAPK8) 100984173(MAPK10) 100990080(MAPK9)
GGO: 101124033(MAPK8) 101133141(MAPK10) 101152026(MAPK9)
PON: 100174482(MAPK10) 100437424(MAPK8) 100459133(MAPK9)
NLE: 100581677(MAPK9) 100602081(MAPK10) 100605285(MAPK8)
MCC: 699736(MAPK10) 711115(MAPK8) 715782(MAPK9)
MCF: 102118497(MAPK9) 102121272(MAPK10) 102126339(MAPK8)
MTHB: 126954697 126956917 126963142
CSAB: 103215844(MAPK8) 103235918(MAPK10) 103245120(MAPK9)
CATY: 105576775(MAPK10) 105590417(MAPK9) 105591436(MAPK8)
PANU: 101005010(MAPK10) 101019884(MAPK8) 101022320(MAPK9)
TGE: 112624632(MAPK10) 112626308(MAPK9) 112631631(MAPK8)
RRO: 104668007(MAPK10) 104676194(MAPK9) 104678447(MAPK8)
RBB: 108517508 108521141(MAPK10) 108537794(MAPK8)
TFN: 117065429(MAPK9) 117082864(MAPK8) 117085362(MAPK10)
PTEH: 111530867(MAPK10) 111535725(MAPK9) 111554538(MAPK8)
CANG: 105517705(MAPK8) 105518701(MAPK10) 105519528(MAPK9)
CJC: 100387686(MAPK9) 100390109(MAPK10) 100392721(MAPK8)
SBQ: 101027742(MAPK9) 101039160(MAPK8) 101048066(MAPK10)
CSYR: 103252280(MAPK9) 103255312(MAPK10) 103272968(MAPK8)
MMUR: 105860097(MAPK8) 105864291 105865754(MAPK9) 105874790(MAPK10)
LCAT: 123621799(MAPK9) 123627295(MAPK10) 123650465(MAPK8)
PCOQ: 105812700(MAPK10) 105815999 105823643(MAPK9)
OGA: 100957169(MAPK9) 100960275(MAPK10) 100967053(MAPK8)
MMU: 26414(Mapk10) 26419(Mapk8) 26420(Mapk9)
MCAL: 110294148(Mapk10) 110304169(Mapk9) 110308920(Mapk8)
MPAH: 110325466(Mapk8) 110330449(Mapk10) 110332652(Mapk9)
RNO: 116554(Mapk8) 25272(Mapk10) 50658(Mapk9)
MCOC: 116067982(Mapk10) 116076765(Mapk9) 116085336(Mapk8)
MUN: 110552285(Mapk8) 110557386(Mapk9)
CGE: 100754361 100764964(Mapk9) 100771734(Mapk8)
MAUA: 101827071(Mapk8) 101832187(Mapk9) 101841730(Mapk10)
PLEU: 114681520(Mapk9) 114691777(Mapk10) 114699348(Mapk8)
MORG: 121440925(Mapk10) 121455025(Mapk8) 121456117(Mapk9)
AAMP: 119811270(Mapk9) 119813574(Mapk10) 119827427(Mapk8)
NGI: 103735023(Mapk8) 103748972(Mapk10) 103749366(Mapk9)
HGL: 101698286(Mapk9) 101712980(Mapk10) 101715259(Mapk8)
CPOC: 100714249(Mapk9) 100718766(Mapk10) 100722333(Mapk8)
DORD: 105988509(Mapk10) 105996777(Mapk9) 105998906(Mapk8)
DSP: 122097824(Mapk10) 122115378(Mapk9) 122116492(Mapk8)
OPI: 101518695(MAPK8) 101524844(MAPK9) 101531453(MAPK10)
TUP: 102472233(MAPK8) 102475730(MAPK10) 102497095(MAPK9)
CFA: 474652(MAPK9) 477746(MAPK8) 478464(MAPK10)
CLUD: 112645941(MAPK10) 112659577(MAPK9) 112671968(MAPK8)
VVP: 112911881(MAPK9) 112913098(MAPK8) 112919676(MAPK10)
VLG: 121482830(MAPK8) 121493739(MAPK10) 121494640(MAPK9)
AML: 100477600(MAPK9) 100477951(MAPK10) 100482196(MAPK8)
UMR: 103667893(MAPK8) 103676947(MAPK10) 103679990(MAPK9)
UAH: 113243106(MAPK8) 113261548(MAPK9) 113263180(MAPK10)
UAR: 123788054(MAPK10) 123790496(MAPK9) 123800287(MAPK8)
MPUF: 101672072(MAPK8) 101676423(MAPK9) 101681349(MAPK10)
ORO: 101367488(MAPK10) 101374143(MAPK8) 101376185(MAPK9)
EJU: 114201201(MAPK9) 114205461(MAPK8) 114224898(MAPK10)
ZCA: 113922602(MAPK8) 113925863(MAPK10) 113928769(MAPK9)
MLX: 118010368 118022776(MAPK8) 118026506(MAPK9)
NSU: 110580283(MAPK9) 110589690(MAPK8) 110591392(MAPK10)
LWW: 102733548(MAPK10) 102739504(MAPK8)
FCA: 101084765(MAPK9) 101091310(MAPK8) 101101463(MAPK10)
PYU: 121010516(MAPK9) 121033019(MAPK10) 121036923(MAPK8)
PBG: 122478691(MAPK10) 122485896(MAPK9) 122492960(MAPK8)
PTG: 102950880(MAPK8) 102959159(MAPK10) 102963096(MAPK9)
PPAD: 109264550(MAPK8) 109276314(MAPK10) 109278973(MAPK9)
AJU: 106969894(MAPK9) 106970668(MAPK10) 106989581(MAPK8)
HHV: 120232781(MAPK8) 120244180(MAPK10) 120245677(MAPK9)
BTA: 534125(MAPK9) 537631(MAPK10) 539941(MAPK8)
BOM: 102266960(MAPK9) 102272421(MAPK10) 102277976(MAPK8)
BIU: 109553773(MAPK8) 109560650(MAPK10) 109561331(MAPK9)
BBUB: 102393434(MAPK8) 102396572(MAPK10) 102403452(MAPK9)
BBIS: 104981526(MAPK9) 104992939(MAPK10) 104998999(MAPK8)
CHX: 100861087(MAPK8) 102170408(MAPK9) 102182774(MAPK10)
OAS: 101116201(MAPK8) 101120665(MAPK10) 101120826(MAPK9)
ODA: 120861535(MAPK10) 120864358(MAPK9) 120865345(MAPK8)
CCAD: 122428339(MAPK10) 122440572(MAPK9) 122446321(MAPK8)
SSC: 100521736(MAPK10) 396609(MAPK9) 396610(MAPK8)
CFR: 102503577(MAPK8) 102509448(MAPK10) 102518561(MAPK9)
CBAI: 105062001(MAPK9) 105075609(MAPK8) 105077723(MAPK10)
CDK: 105091591(MAPK10) 105094659(MAPK8) 105100625(MAPK9)
VPC: 102528221(MAPK8) 102539859(MAPK10) 102543430(MAPK9)
BACU: 102997603(MAPK8) 103007019(MAPK9) 103008728(MAPK10)
LVE: 103078792(MAPK10) 103084630(MAPK8) 103087676(MAPK9)
OOR: 101277656(MAPK10) 101281228(MAPK8) 101287701(MAPK9)
DLE: 111168108(MAPK10) 111169265(MAPK9) 111169895(MAPK8)
PCAD: 102977417(MAPK9) 102984741(MAPK10) 102996353(MAPK8)
PSIU: 116741257(MAPK8) 116751302(MAPK9) 116754735(MAPK10)
ECB: 100051798(MAPK8) 100052608(MAPK10) 100057961(MAPK9)
EPZ: 103549414(MAPK8) 103553980(MAPK10) 103567629(MAPK9)
EAI: 106831384(MAPK8) 106839421(MAPK10) 106843729(MAPK9)
MYB: 102246292(MAPK8) 102259984(MAPK9) 102263026(MAPK10)
MYD: 102764416(MAPK8) 102772062(MAPK9) 102775351
MMYO: 118652068 118657754(MAPK9) 118670993(MAPK10) 118679322(MAPK8)
MLF: 102418507(MAPK9) 102430582(MAPK8) 102437455(MAPK10)
MNA: 107527953(MAPK8) 107528432(MAPK9) 107537133(MAPK10)
PKL: 118725940(MAPK9) 118728660(MAPK10) 118732117(MAPK8)
HAI: 109377948 109392215(MAPK8) 109392748(MAPK9)
DRO: 112296379(MAPK9) 112305558(MAPK8) 112317841(MAPK10)
SHON: 118976281(MAPK10) 118994117(MAPK8) 118995102(MAPK9)
AJM: 119042614(MAPK9) 119046845(MAPK8) 119062834(MAPK10)
PDIC: 114492422(MAPK10) 114496029(MAPK8) 114509631(MAPK9)
PHAS: 123806902(MAPK10) 123807193(MAPK9) 123820887(MAPK8)
MMF: 118615122(MAPK9) 118632456(MAPK8) 118642157(MAPK10)
RFQ: 117016634(MAPK9) 117022220(MAPK10) 117026302 117035933(MAPK8)
PALE: 102885064(MAPK10) 102890689(MAPK9) 102892777(MAPK8)
PGIG: 120588349(MAPK10) 120609636(MAPK8) 120616614(MAPK9)
PVP: 105288933(MAPK8) 105289628(MAPK10) 105299978(MAPK9)
RAY: 107509910(MAPK8) 107512328(MAPK9) 107515392(MAPK10)
TOD: 119234816(MAPK8) 119236621(MAPK9) 119256545 119261431(MAPK10)
SARA: 101538553(MAPK10) 101556063(MAPK8) 101556557(MAPK9)
LAV: 100654943(MAPK9) 100673395(MAPK10) 100674229(MAPK8)
ETF: 101645489(MAPK8) 101653598(MAPK9) 101654493(MAPK10)
DNM: 101416102(MAPK10) 101421932(MAPK8) 101423710(MAPK9)
MDO: 100028089(MAPK9) 100618895(MAPK10)
GAS: 123237465(MAPK9) 123238271(MAPK8) 123251179(MAPK10)
SHR: 100924267(MAPK9) 100928480(MAPK10) 100930815(MAPK8)
PCW: 110209710(MAPK10) 110215514(MAPK8) 110216709(MAPK9)
OAA: 100073424(MAPK9) 100076033(MAPK8) 100082590(MAPK10)
GGA: 395983(MAPK9) 422592(MAPK10) 423778(MAPK8)
PCOC: 116231100(MAPK10) 116232182(MAPK9) 116238149(MAPK8)
MGP: 100541011(MAPK9) 100542628(MAPK10) 100547737(MAPK8)
CJO: 107313439(MAPK10) 107315851(MAPK8) 107320159(MAPK9)
NMEL: 110398630(MAPK10) 110399325(MAPK8) 110405490(MAPK9)
APLA: 101793594(MAPK8) 101799011(MAPK9) 101799776(MAPK10) 113841885
ACYG: 106032805(MAPK9) 106041872(MAPK10) 106047189(MAPK8)
AFUL: 116489162(MAPK10) 116491194(MAPK8) 116495022(MAPK9)
TGU: 100220867(MAPK8) 100223519(MAPK10) 100225285(MAPK9)
LSR: 110475182(MAPK8) 110480954(MAPK10) 110482776(MAPK9)
SCAN: 103813947(MAPK8) 103817284(MAPK9) 103826066(MAPK10)
PMOA: 120498451(MAPK9) 120502221(MAPK8) 120502789(MAPK10)
OTC: 121332208(MAPK9) 121339886(MAPK10) 121341643(MAPK8)
PRUF: 121350038(MAPK8) 121361485(MAPK9) 121365224(MAPK10)
GFR: 102036009(MAPK8) 102043222(MAPK9) 102043776(MAPK10)
FAB: 101809052(MAPK10) 101817339(MAPK8) 101819306(MAPK9)
PHI: 102099159(MAPK10) 102106744(MAPK9) 102114724(MAPK8)
PMAJ: 107203419(MAPK10) 107206805(MAPK8) 107210724(MAPK9)
CCAE: 111928823(MAPK10) 111931141(MAPK8) 111935562(MAPK9)
CCW: 104689594(MAPK9) 104696634(MAPK8) 104697227(MAPK10)
CBRC: 103611388(MAPK9) 103622357(MAPK10) 103624489(MAPK8)
ETL: 114054718(MAPK8) 114059149(MAPK10) 114065198(MAPK9)
ZAB: 102060543(MAPK8) 102068975(MAPK9) 102070887
ACHL: 103806889(MAPK9) 103811480(MAPK8) 103812215
FPG: 101917138(MAPK10) 101921076(MAPK9) 101924129(MAPK8)
FCH: 102047380(MAPK8) 102054176(MAPK10) 102055660(MAPK9)
CLV: 102085027(MAPK9) 102085840(MAPK10) 102087983(MAPK8)
EGZ: 104128427(MAPK9) 104129145(MAPK8) 104133994(MAPK10)
NNI: 104013238(MAPK8) 104018444(MAPK9) 104019815(MAPK10)
PLET: 104620209(MAPK8) 104622174(MAPK9) 104624070(MAPK10)
PCAO: 104043989 104049434(MAPK9) 104053402(MAPK8)
ACUN: 113479790(MAPK10) 113481395(MAPK8) 113485089(MAPK9)
TALA: 104360918(MAPK9) 104365312(MAPK10) 104368953(MAPK8)
PADL: 103913739(MAPK8) 103915758(MAPK9) 103918603(MAPK10)
AFOR: 103897639(MAPK8) 103899746(MAPK10) 103904405(MAPK9)
ACHC: 115334063(MAPK9) 115338798(MAPK10) 115347976(MAPK8)
HALD: 104317444(MAPK8) 104317803(MAPK9) 104324418
HLE: 104829319(MAPK8) 104829902(MAPK10) 104838882(MAPK9)
CCRI: 104164462(MAPK9) 104165937 104168638(MAPK8)
CSTI: 104556725(MAPK8) 104557782(MAPK9) 104562594
EHS: 104509339 104514674(MAPK9)
CMAC: 104476736 104482156(MAPK8) 104483661(MAPK9)
MUI: 104534693(MAPK9) 104544253
FGA: 104075665(MAPK8) 104080968(MAPK9)
GSTE: 104255912(MAPK9) 104261666(MAPK8) 104262317
LDI: 104351895(MAPK9) 104354569(MAPK8)
MNB: 103772180(MAPK8) 103775121 103779642(MAPK9)
OHA: 104326885(MAPK9) 104331780(MAPK10) 104337811(MAPK8)
NNT: 104402014(MAPK8) 104406818(MAPK10) 104408146(MAPK9)
DPUB: 104297715(MAPK8) 104309327 104309863(MAPK9)
PGUU: 104463869(MAPK9) 104468340
ACAR: 104520979(MAPK9) 104527571(MAPK8) 104530925
CPEA: 104385199(MAPK10) 104386555(MAPK9) 104391113(MAPK8)
AVIT: 104270528(MAPK8) 104273048(MAPK9) 104276958(MAPK10)
CVF: 104285473(MAPK10) 104289724(MAPK8) 104293102(MAPK9)
CUCA: 104058532(MAPK10) 104059310(MAPK9) 104067885(MAPK8)
TEO: 104377774(MAPK9) 104379231 104379494(MAPK8)
BRHI: 104490313(MAPK9) 104494032(MAPK8) 104495861
AAM: 106493457(MAPK9) 106496655(MAPK10) 106497812(MAPK8)
AROW: 112963855(MAPK8) 112964950(MAPK9) 112967355(MAPK10)
NPD: 112948967(MAPK10) 112954523(MAPK9) 112956827(MAPK8)
TGT: 104567755(MAPK9) 104573205(MAPK8) 104573426
DNE: 112984234(MAPK9) 112984720(MAPK10) 112989234(MAPK8)
SCAM: 104142382(MAPK9) 104145156(MAPK10) 104146010(MAPK8)
ASN: 102374542 102376040(MAPK9) 102376154(MAPK8)
AMJ: 102566087(MAPK10) 102570366(MAPK8) 102570628(MAPK9)
CPOO: 109310131(MAPK9) 109322061(MAPK10) 109323949(MAPK8)
GGN: 109287450(MAPK8) 109289915(MAPK9) 109303636(MAPK10)
PSS: 102453224(MAPK9) 102459702(MAPK8) 102460734(MAPK10)
CMY: 102932835(MAPK10) 102934812(MAPK9) 102935187(MAPK8)
CPIC: 101931056(MAPK8) 101936886(MAPK10) 101952425(MAPK9)
TST: 117877876(MAPK10) 117879770(MAPK8) 117882136(MAPK9)
CABI: 116834967(MAPK8) 116836546(MAPK10) 116837726(MAPK9)
MRV: 120368657(MAPK8) 120369865(MAPK9) 120405833(MAPK10)
ACS: 100558211(mapk10) 100561907(mapk8) 100565814(mapk9)
PVT: 110073473(MAPK9) 110085327(MAPK10) 110087777(MAPK8)
SUND: 121923830(MAPK9) 121931541(MAPK10)
PBI: 103049456(MAPK10) 103059296(MAPK9) 103060996
PMUR: 107293954(MAPK8) 107294632(MAPK9) 107303183(MAPK10)
CTIG: 120307740 120317739(MAPK9) 120319588(MAPK8)
TSR: 106539258(MAPK8) 106547350 106550161(MAPK9)
PGUT: 117655531(MAPK9) 117664553(MAPK8) 117678928(MAPK10)
VKO: 123022757(MAPK10) 123032363(MAPK8) 123035762(MAPK9)
PMUA: 114591317(MAPK9) 114596969(MAPK8) 114603995(MAPK10)
ZVI: 118080395(MAPK9) 118084127(MAPK10) 118096231(MAPK8)
XLA: 108704101(mapk10.S) 108711504(mapk10.L) 379876(mapk8.L) 398499(mapk8.S)
XTR: 100170194(mapk8) 779515(mapk10)
NPR: 108794648 108804455(MAPK10)
RTEM: 120909277(MAPK8) 120915815(MAPK10)
BBUF: 120991666(MAPK10) 121003247(MAPK8)
BGAR: 122926653(MAPK10) 122942594(MAPK8)
DRE: 100149273(mapk9) 562720(mapk8a) 569698(mapk10) 65236(mapk8b)
PPRM: 120466717(mapk8b) 120479574(mapk8a) 120479828(mapk10) 120494671(mapk9)
MAMB: 125252240(mapk9) 125252441(mapk10) 125255077(mapk8b) 125277047(mapk8a)
IPU: 108263675(mapk8a) 108274025(mapk8b) 108278438(mapk10) 108278622(mapk9)
SMEO: 124388678(mapk8b) 124396097(mapk8a) 124397718(mapk9) 124397814(mapk10)
TFD: 113639911(mapk8a) 113646914(mapk9) 113650632(mapk8b) 113654498(mapk10)
NCC: 104954536(mapk10) 104962527(mapk8) 104965693(mapk9)
ELY: 117246944(mapk8b) 117248336(mapk8a) 117260760(mapk9) 117269589(mapk10)
EFO: 125880486(mapk8b) 125894559(mapk9) 125903016(mapk8a) 125905962(mapk10)
PLEP: 121947706(mapk9) 121954271(mapk8a) 121958808(mapk8b) 121959676(mapk10)
SLUC: 116048711(mapk8b) 116053441(mapk8a) 116063029(mapk10) 116064329(mapk9)
ECRA: 117936667(mapk8b) 117952085(mapk9) 117959822(mapk10) 117960867(mapk8a)
GAT: 120817444(mapk9) 120819217(mapk8b) 120820300(mapk8a) 120831463(mapk10)
PPUG: 119210947(mapk9) 119212533(mapk8b) 119213781(mapk8a) 119226214(mapk10)
MSAM: 119888580(mapk9) 119915031(mapk10) 119915573(mapk8b) 119917030(mapk8a)
CUD: 121510585(mapk8a) 121516088(mapk9) 121525050(mapk10) 121528815(mapk8b)
ALAT: 119007321(mapk9) 119009619(mapk8b) 119030334(mapk10) 119033738(mapk8a)
MZE: 101476882 101477577 101480702(mapk8) 101486303(mapk10)
OAU: 116319638(mapk8a) 116327319(mapk8b) 116329107(mapk9) 116331794(mapk10)
OML: 112153234(mapk9) 112154188(mapk8b) 112161471(mapk8a) 112163450(mapk10)
XMA: 102221148(mapk8) 102226476(mapk10) 102234094 102237237
PRET: 103471253 103473893(mapk10) 103476945 103482024(mapk8)
PFOR: 103134016 103135541 103142718(mapk10) 103143577(mapk8)
PMEI: 106915127 106917997(mapk10) 106920878 106924329(mapk8)
GAF: 122823403(mapk8b) 122836543(mapk9) 122842229(mapk8a) 122846859(mapk10)
CVG: 107085828(mapk10) 107086602(mapk8) 107101533 107102050
CTUL: 119776529(mapk10) 119790706(mapk8a) 119792465(mapk9) 119795289
GMU: 124859135(mapk8a) 124860150(mapk9) 124872468(mapk10) 124875307(mapk8b)
NFU: 107374715(mapk10) 107375638(mapk8) 107375912 107388204
KMR: 108230987(mapk10) 108234067(mapk8a) 108240588(mapk9)
ALIM: 106516220(mapk10) 106517558 106524736(mapk8)
NWH: 119408491(mapk9) 119412019(mapk8a) 119424857(mapk10)
MCEP: 124997018(mapk10) 125008712(mapk9) 125019343(mapk8a) 125022122(mapk8b)
SSEN: 122758191(mapk10) 122761317 122778368(mapk9) 122780575 122781986(mapk8a)
HHIP: 117752542(mapk8b) 117769257(mapk9) 117772227(mapk10) 117775780(mapk8a)
HSP: 118098029(mapk10) 118100088(mapk8b) 118112070(mapk9) 118118847(mapk8a)
LCF: 108873059(mapk8b) 108874078 108888287(mapk8a) 108899231
XGL: 120785433(mapk9) 120794394(mapk8b) 120796205(mapk8a) 120806753(mapk10)
BPEC: 110157114 110157667 110159805(mapk8) 110160610(mapk10)
MALB: 109961054(mapk8) 109969172 109972323(mapk10) 109973158
BSPL: 114841906(mapk8a) 114845408(mapk8b) 114864012(mapk9) 114867198(mapk10)
AANG: 118212863(mapk10) 118217861(mapk8a) 118220848(mapk8b) 118223663(mapk9) 118236139
LOC: 102687878(mapk10) 102691138 102692400(mapk8)
PSEX: 120527417(mapk10) 120542011
LCM: 102351693(MAPK9) 102351958(MAPK10) 102357573(MAPK8)
BFO: 118411418
BBEL: 109481359
CIN: 778660(jnk)
SCLV: 120330741
SPU: 580919
APLC: 110979079
AJC: 117106433
SKO: 100374258
DME: Dmel_CG5680(bsk)
DER: 6543257
DSE: 6611938
DSI: Dsimw501_GD22289(Dsim_GD22289)
DAN: 6496954
DSR: 110183323
DPO: 26533386
DPE: 6589301
DMN: 108161325
DWI: 6649965
DGR: 6567095
DAZ: 108610426
DNV: 108649583
DHE: 111603998
DVI: 6627383
CCAT: 101449698
BOD: 106614716
HIS: 119647241
CNS: 116345496
BCOO: 119078838
AME: 409286
ALAB: 122716347
BIM: 100740816
BBIF: 117210694
BVK: 117237534
BVAN: 117164125
BTER: 100631091
BPYO: 122565878
CCAL: 108628152
OBB: 114877625
MGEN: 117217903
NMEA: 116434870
CGIG: 122398247
SOC: 105195964
MPHA: 105837888
AEC: 105148788
ACEP: 105619924
PBAR: 105426774
VEM: 105558786
HST: 105191959
DQU: 106748609
CFO: 105253069
FEX: 115235148
LHU: 105670179
PGC: 109856677
OBO: 105285161
PCF: 106786247
PFUC: 122525358
VPS: 122633268
NVI: 100121916
CSOL: 105368830
TPRE: 106656715
MDL: 103571069
CGLO: 123272985
FAS: 105267383
DAM: 107038916
AGIF: 122861066
CINS: 118070617
LHT: 122499323
CCIN: 107268543
TCA: 663836(bsk)
SOY: 115881088
ATD: 109597490
CSET: 123316810
AGB: 108903975
LDC: 111517435
NVL: 108560378
APLN: 108733634
PPYR: 116178567
OTU: 111426275
BMOR: 100126162(Jnk)
BMAN: 114250596
MSEX: 115444202
BANY: 112044077
NIQ: 126771627
PMAC: 106713114
PPOT: 106105079
PXU: 106125616
PRAP: 110999109
PBX: 123713134
PNAP: 125060634
ZCE: 119840146
CCRC: 123698275
HAW: 110380242
HZE: 124638744
TNL: 113503670
SLIU: 111354082
API: 100163276
DNX: 107172095
AGS: 114128352
RMD: 113556940
BTAB: 109038553
DCI: 103508970
CLEC: 106665032
FOC: 113203867
TPAL: 117654111
ZNE: 110831056
CSEC: 111871173
SGRE: 126336637
FCD: 110845183
PVM: 113811200
PJA: 122242109
PCHN: 125038936
HAME: 121868437
PCLA: 123764277
PTRU: 123500119
HAZT: 108675035
EAF: 111709931
LSM: 121127343
DSV: 119435068
RSAN: 119406104
RMP: 119177229
TUT: 107361712
CEL: CELE_B0478.1(jnk-1) CELE_T07A9.3(kgb-1) CELE_ZC416.4(kgb-2)
CBR: CBG_05733(Cbr-jnk-1) CBG_13536(Cbr-kgb-1)
BMY: BM_BM1820(Bma-jnk-1) BM_BM9350(Bm9350)
TSP: Tsp_05770
PCAN: 112577050
BGT: 106057561
GAE: 121379983
HRF: 124138176
HRJ: 124289321
CRG: 105338795
PMAX: 117325357
MMER: 123564407
OBI: 106878992
OSN: 115220678
LAK: 106176904
EPA: 110249370
ATEN: 116298847
ADF: 107341807
AMIL: 114970322
PDAM: 113664928
SPIS: 111341356
DGT: 114527520
XEN: 124447687
HMG: 100201400
AQU: 100636234
NCOL: 116268183
 » show all
Reference
PMID:8137421
  Authors
Derijard B, Hibi M, Wu IH, Barrett T, Su B, Deng T, Karin M, Davis RJ
  Title
JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain.
  Journal
Cell 76:1025-37 (1994)
DOI:10.1016/0092-8674(94)90380-8
  Sequence
[hsa:5599]
Reference
  Authors
Miotto B, Struhl K
  Title
JNK1 phosphorylation of Cdt1 inhibits recruitment of HBO1 histone acetylase and blocks replication licensing in response to stress.
  Journal
Mol Cell 44:62-71 (2011)
DOI:10.1016/j.molcel.2011.06.021
Reference
  Authors
Kawasaki M, Hisamoto N, Iino Y, Yamamoto M, Ninomiya-Tsuji J, Matsumoto K
  Title
A Caenorhabditis elegans JNK signal transduction pathway regulates coordinated movement via type-D GABAergic motor neurons.
  Journal
EMBO J 18:3604-15 (1999)
DOI:10.1093/emboj/18.13.3604
  Sequence
LinkDB

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