KEGG   ORTHOLOGY: K08041
Entry
K08041                      KO                                     
Symbol
ADCY1
Name
adenylate cyclase 1 [EC:4.6.1.1]
Pathway
map00230  Purine metabolism
map01100  Metabolic pathways
map01522  Endocrine resistance
map04015  Rap1 signaling pathway
map04020  Calcium signaling pathway
map04022  cGMP-PKG signaling pathway
map04024  cAMP signaling pathway
map04062  Chemokine signaling pathway
map04072  Phospholipase D signaling pathway
map04114  Oocyte meiosis
map04211  Longevity regulating pathway
map04213  Longevity regulating pathway - multiple species
map04261  Adrenergic signaling in cardiomyocytes
map04270  Vascular smooth muscle contraction
map04371  Apelin signaling pathway
map04540  Gap junction
map04611  Platelet activation
map04713  Circadian entrainment
map04714  Thermogenesis
map04720  Long-term potentiation
map04723  Retrograde endocannabinoid signaling
map04724  Glutamatergic synapse
map04725  Cholinergic synapse
map04727  GABAergic synapse
map04750  Inflammatory mediator regulation of TRP channels
map04911  Insulin secretion
map04912  GnRH signaling pathway
map04913  Ovarian steroidogenesis
map04914  Progesterone-mediated oocyte maturation
map04915  Estrogen signaling pathway
map04916  Melanogenesis
map04918  Thyroid hormone synthesis
map04921  Oxytocin signaling pathway
map04923  Regulation of lipolysis in adipocytes
map04925  Aldosterone synthesis and secretion
map04926  Relaxin signaling pathway
map04927  Cortisol synthesis and secretion
map04928  Parathyroid hormone synthesis, secretion and action
map04934  Cushing syndrome
map04935  Growth hormone synthesis, secretion and action
map04970  Salivary secretion
map04971  Gastric acid secretion
map04972  Pancreatic secretion
map04976  Bile secretion
map05032  Morphine addiction
map05142  Chagas disease
map05146  Amoebiasis
map05163  Human cytomegalovirus infection
map05166  Human T-cell leukemia virus 1 infection
map05200  Pathways in cancer
map05207  Chemical carcinogenesis - receptor activation
map05414  Dilated cardiomyopathy
Disease
H00605  Deafness, autosomal recessive
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    K08041  ADCY1; adenylate cyclase 1
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    K08041  ADCY1; adenylate cyclase 1
   04371 Apelin signaling pathway
    K08041  ADCY1; adenylate cyclase 1
   04020 Calcium signaling pathway
    K08041  ADCY1; adenylate cyclase 1
   04072 Phospholipase D signaling pathway
    K08041  ADCY1; adenylate cyclase 1
   04024 cAMP signaling pathway
    K08041  ADCY1; adenylate cyclase 1
   04022 cGMP-PKG signaling pathway
    K08041  ADCY1; adenylate cyclase 1
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    K08041  ADCY1; adenylate cyclase 1
  09144 Cellular community - eukaryotes
   04540 Gap junction
    K08041  ADCY1; adenylate cyclase 1
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    K08041  ADCY1; adenylate cyclase 1
   04062 Chemokine signaling pathway
    K08041  ADCY1; adenylate cyclase 1
  09152 Endocrine system
   04911 Insulin secretion
    K08041  ADCY1; adenylate cyclase 1
   04923 Regulation of lipolysis in adipocytes
    K08041  ADCY1; adenylate cyclase 1
   04912 GnRH signaling pathway
    K08041  ADCY1; adenylate cyclase 1
   04913 Ovarian steroidogenesis
    K08041  ADCY1; adenylate cyclase 1
   04915 Estrogen signaling pathway
    K08041  ADCY1; adenylate cyclase 1
   04914 Progesterone-mediated oocyte maturation
    K08041  ADCY1; adenylate cyclase 1
   04921 Oxytocin signaling pathway
    K08041  ADCY1; adenylate cyclase 1
   04926 Relaxin signaling pathway
    K08041  ADCY1; adenylate cyclase 1
   04935 Growth hormone synthesis, secretion and action
    K08041  ADCY1; adenylate cyclase 1
   04918 Thyroid hormone synthesis
    K08041  ADCY1; adenylate cyclase 1
   04928 Parathyroid hormone synthesis, secretion and action
    K08041  ADCY1; adenylate cyclase 1
   04916 Melanogenesis
    K08041  ADCY1; adenylate cyclase 1
   04925 Aldosterone synthesis and secretion
    K08041  ADCY1; adenylate cyclase 1
   04927 Cortisol synthesis and secretion
    K08041  ADCY1; adenylate cyclase 1
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    K08041  ADCY1; adenylate cyclase 1
   04270 Vascular smooth muscle contraction
    K08041  ADCY1; adenylate cyclase 1
  09154 Digestive system
   04970 Salivary secretion
    K08041  ADCY1; adenylate cyclase 1
   04971 Gastric acid secretion
    K08041  ADCY1; adenylate cyclase 1
   04972 Pancreatic secretion
    K08041  ADCY1; adenylate cyclase 1
   04976 Bile secretion
    K08041  ADCY1; adenylate cyclase 1
  09156 Nervous system
   04724 Glutamatergic synapse
    K08041  ADCY1; adenylate cyclase 1
   04727 GABAergic synapse
    K08041  ADCY1; adenylate cyclase 1
   04725 Cholinergic synapse
    K08041  ADCY1; adenylate cyclase 1
   04720 Long-term potentiation
    K08041  ADCY1; adenylate cyclase 1
   04723 Retrograde endocannabinoid signaling
    K08041  ADCY1; adenylate cyclase 1
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    K08041  ADCY1; adenylate cyclase 1
  09149 Aging
   04211 Longevity regulating pathway
    K08041  ADCY1; adenylate cyclase 1
   04213 Longevity regulating pathway - multiple species
    K08041  ADCY1; adenylate cyclase 1
  09159 Environmental adaptation
   04713 Circadian entrainment
    K08041  ADCY1; adenylate cyclase 1
   04714 Thermogenesis
    K08041  ADCY1; adenylate cyclase 1
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K08041  ADCY1; adenylate cyclase 1
   05207 Chemical carcinogenesis - receptor activation
    K08041  ADCY1; adenylate cyclase 1
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K08041  ADCY1; adenylate cyclase 1
   05163 Human cytomegalovirus infection
    K08041  ADCY1; adenylate cyclase 1
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    K08041  ADCY1; adenylate cyclase 1
   05142 Chagas disease
    K08041  ADCY1; adenylate cyclase 1
  09165 Substance dependence
   05032 Morphine addiction
    K08041  ADCY1; adenylate cyclase 1
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    K08041  ADCY1; adenylate cyclase 1
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    K08041  ADCY1; adenylate cyclase 1
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    K08041  ADCY1; adenylate cyclase 1
Enzymes [BR:ko01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     K08041  ADCY1; adenylate cyclase 1
Other DBs
RN: R00089 R00434
GO: 0008294
Genes
HSA: 107(ADCY1)
PTR: 463392(ADCY1)
PPS: 100984585(ADCY1)
GGO: 101125943(ADCY1)
PON: 100449504(ADCY1)
NLE: 100595636(ADCY1)
MCC: 697230(ADCY1)
MCF: 102147015(ADCY1)
CSAB: 103226115(ADCY1)
CATY: 105588320(ADCY1)
PANU: 100998237(ADCY1)
TGE: 112620936(ADCY1)
RRO: 104671165(ADCY1)
RBB: 108534793(ADCY1)
TFN: 117073333(ADCY1)
CJC: 100394265(ADCY1)
SBQ: 101027981(ADCY1)
MMUR: 105870668(ADCY1)
OGA: 100955472(ADCY1)
MMU: 432530(Adcy1)
MCAL: 110305998(Adcy1)
MPAH: 110330584(Adcy1)
RNO: 305509(Adcy1)
MCOC: 116069116(Adcy1)
MUN: 110555169(Adcy1)
CGE: 100764561(Adcy1)
PLEU: 114693962(Adcy1)
NGI: 103741433(Adcy1)
HGL: 101711366(Adcy1)
CPOC: 100715672(Adcy1)
CCAN: 109694874(Adcy1)
DORD: 105998287(Adcy1)
DSP: 122128067(Adcy1)
OPI: 101533323(ADCY1)
TUP: 102468873(ADCY1)
CFA: 607357(ADCY1)
VVP: 112911455(ADCY1)
VLG: 121490100(ADCY1) 121492610
AML: 100472777(ADCY1)
UAH: 113257705(ADCY1)
UAR: 123789481(ADCY1)
ELK: 111157054
LLV: 125081029
MPUF: 101676834(ADCY1)
ORO: 101379158(ADCY1)
EJU: 114213699(ADCY1)
ZCA: 113911474(ADCY1)
MLX: 118024512(ADCY1)
FCA: 101101375(ADCY1)
PYU: 121016977(ADCY1)
PBG: 122487650(ADCY1)
PTG: 102961712(ADCY1)
PPAD: 109267948(ADCY1)
AJU: 106968223(ADCY1)
HHV: 120238897(ADCY1)
BTA: 281601(ADCY1)
BOM: 102267116(ADCY1)
BIU: 109557525(ADCY1)
BBUB: 102415323(ADCY1)
CHX: 102180724(ADCY1)
OAS: 101117327(ADCY1)
ODA: 120877473(ADCY1)
CCAD: 122438514(ADCY1)
SSC: 100624934(ADCY1)
CFR: 102517882(ADCY1)
CBAI: 105080525(ADCY1)
CDK: 105095715(ADCY1)
VPC: 102538400(ADCY1)
BACU: 102998650(ADCY1)
LVE: 103081539(ADCY1)
OOR: 101278368(ADCY1)
DLE: 111184534(ADCY1)
PCAD: 102981199(ADCY1)
PSIU: 116759445(ADCY1)
ECB: 100065563(ADCY1)
EPZ: 103550430(ADCY1)
EAI: 106822932(ADCY1)
MYB: 102257679(ADCY1)
MYD: 102759978(ADCY1)
MMYO: 118665883(ADCY1)
MNA: 107526004(ADCY1)
PKL: 118720332(ADCY1)
HAI: 109373011(ADCY1)
DRO: 112306844(ADCY1)
SHON: 118983483(ADCY1)
AJM: 119057313(ADCY1)
PDIC: 114490247
PHAS: 123811468(ADCY1)
MMF: 118620164(ADCY1)
RFQ: 117012305(ADCY1)
PALE: 102887497(ADCY1)
PGIG: 120589581(ADCY1)
PVP: 105308299
RAY: 107512406(ADCY1)
MJV: 108403511(ADCY1)
TOD: 119231485(ADCY1)
SARA: 101557843(ADCY1)
LAV: 100671072(ADCY1)
TMU: 101354868
DNM: 101411559(ADCY1)
MDO: 100030463(ADCY1)
GAS: 123247570(ADCY1)
SHR: 100922193(ADCY1)
PCW: 110197533(ADCY1)
OAA: 103168601(ADCY1)
GGA: 420788(ADCY1)
PCOC: 116228264(ADCY1)
CJO: 107309766(ADCY1)
NMEL: 110390836(ADCY1)
APLA: 101804073(ADCY1)
ACYG: 106046455(ADCY1)
AFUL: 116486732(ADCY1)
TGU: 100226080(ADCY1)
LSR: 110477391(ADCY1)
SCAN: 103819377(ADCY1)
PMOA: 120503563(ADCY1)
OTC: 121333301(ADCY1)
PRUF: 121356124
GFR: 102040399(ADCY1)
FAB: 101807752(ADCY1)
PHI: 102110269(ADCY1)
PMAJ: 107201036(ADCY1)
CCAE: 111923918(ADCY1)
CCW: 104689252(ADCY1)
ETL: 114068677(ADCY1)
ZAB: 102073009(ADCY1)
FPG: 101914769(ADCY1)
FCH: 102056699(ADCY1)
CLV: 102094612(ADCY1)
EGZ: 104125965(ADCY1)
NNI: 104015394(ADCY1)
ACUN: 113477314(ADCY1)
TALA: 104361601(ADCY1)
PADL: 103916246(ADCY1)
ACHC: 115352949(ADCY1)
AAM: 106492856(ADCY1)
AROW: 112965172(ADCY1)
NPD: 112942706(ADCY1)
DNE: 112997517(ADCY1)
ASN: 102372645(ADCY1)
AMJ: 102573818(ADCY1)
CPOO: 109310610(ADCY1)
GGN: 109291654(ADCY1)
PSS: 102445759(ADCY1)
CMY: 102939135(ADCY1)
CPIC: 101935286(ADCY1)
TST: 117872635(ADCY1)
CABI: 116834610(ADCY1)
MRV: 120398088(ADCY1)
ACS: 100564004(adcy1)
PVT: 110091617(ADCY1)
SUND: 121933610
PBI: 103068192
PMUR: 107287848(ADCY1)
TSR: 106543976(ADCY1)
PGUT: 117664957(ADCY1)
VKO: 123035478(ADCY1)
PMUA: 114607043(ADCY1)
ZVI: 118077681(ADCY1)
GJA: 107119176(ADCY1)
XLA: 108705348(adcy1.S) 108718988(adcy1.L)
XTR: 100492373(adcy1)
NPR: 108796974(ADCY1)
RTEM: 120940455(ADCY1)
BBUF: 121001993(ADCY1)
BGAR: 122939040(ADCY1)
DRE: 557026(adcy1a) 569499(adcy1b)
SRX: 107708029 107712833 107721119 107722299
SANH: 107662517 107687179 107697434 107698950
SGH: 107559745 107563079 107568325 107568330 107581454
CCAR: 109062843 109064752 109104203
CAUA: 113039324 113046191 113063272 113121087
IPU: 108257925(adcy1a) 108267157(adcy1b)
PHYP: 113545185 113547307(adcy1)
SMEO: 124377387(adcy1a) 124387690(adcy1b)
AMEX: 103026793 103044091
EEE: 113582988 113588648
TRU: 101074661(adcy1)
TNG: GSTEN00004784G001 GSTEN00012275G001
LCO: 104927730 104929332
NCC: 104962323
CGOB: 115007486 115022993
ELY: 117254244 117272452
PLEP: 121941164 121952008
SLUC: 116038182 116046040
ECRA: 117950827 117954024
PFLV: 114560976 114565945
GAT: 120816002 120824385
PPUG: 119209156 119216787
MSAM: 119900267 119902050
CUD: 121512420 121520404
MZE: 101466326 101470179
ONL: 100702846 100706434
OAU: 116314396(adcy1a) 116318699
OLA: 101165720 101166500
OML: 112147429(adcy1a) 112150580
XMA: 102227141 102232616
XCO: 114146909 114151481
XHE: 116721781 116726292
PRET: 103463403 103479636 108167103
PFOR: 103129619 103142996
PLAI: 106948616(adcy1)
PMEI: 106914433 106925933
GAF: 122838016 122841230
CVG: 107083005 107092411
CTUL: 119787741(adcy1a) 119795701
GMU: 124870286 124874521
NFU: 107383914 107393050
KMR: 108239683 108248366
ALIM: 106532267 106533941
NWH: 119407638(adcy1a) 119415057
AOCE: 111568697 111569882
CSEM: 103396283 103399855
POV: 109637504(adcy1) 109643317
SSEN: 122771664 122780642(adcy1a)
HHIP: 117760300 117778082
LCF: 108879606 108883418
SDU: 111227562 111231027
SLAL: 111670478 111671788
XGL: 120790683 120799286
HCQ: 109521217 109524669
BPEC: 110159474(adcy1) 110172262
MALB: 109957656 109961254
SASA: 106560395 106569164 106584068 106599721
OTW: 112226841 112251320 112260578
OMY: 110508629 110523017 110530970
OGO: 123997178(adcy1a) 124010162 124041773
ONE: 115102992 115114521
SALP: 111978905 112070221
SNH: 120020682 120054302 120055308
ELS: 105011947 105018654
SFM: 108937596 108939197
PKI: 111845834 111850159
AANG: 118224561(adcy1a) 118233055
LOC: 102692556(adcy1)
PSPA: 121313146 121314511
ARUT: 117394455 117399269
CMK: 103187011
RTP: 109910491
DME: Dmel_CG9533(rut)
DER: 6550736
DSE: 6619554
DSI: Dsimw501_GD15838(Dsim_rut)
DYA: Dyak_GE16101
DAN: 6504270
DSR: 110182103
DPO: Dpse_GA29217
DPE: 6598394
DMN: 108161375
DWI: 6653130
DGR: 6564853
DMO: Dmoj_GI15743
DAZ: 108618185
DNV: 108656529
DHE: 111600202
DVI: 6631926
CCAT: 101452382
BOD: 106625393
MDE: 101890662
SCAC: 106085694
LCQ: 111684525
AGA: AgaP_AGAP000727
ACOZ: 120959989
AARA: 120906721
AAG: 5571379
AALB: 109401880
CQU: CpipJ_CPIJ017287 CpipJ_CPIJ019946
CPII: 120420252
CNS: 116346299
TCA: 661438(rut)
DPA: 109546607
SOY: 115880233
ATD: 109599121 109606542
CSET: 123312770
AGB: 108904553
LDC: 111515079
NVL: 108566779
APLN: 108736715
PPYR: 116176544
OTU: 111427516
BMOR: 101741402
BMAN: 114248717
MSEX: 115454133
DPL: KGM_213815
BANY: 112053190
PMAC: 106720337
PPOT: 106109142
PXU: 106127108
PRAP: 110991594
ZCE: 119834784
HAW: 110369899
TNL: 113501500
OFU: 114365405
PXY: 105380532
API: 100164676
DNX: 107168960
AGS: 114126041
RMD: 113559605
BTAB: 109030117
DCI: 103514692
CLEC: 106662482
HHAL: 106680561 106692546
NLU: 111062756
PHU: Phum_PHUM559430
FOC: 113210518
ZNE: 110826860
CSEC: 111871901
FCD: 110861546
DPX: DAPPUDRAFT_48469(Adcy2)
DMK: 116925520
PVM: 113821369
PJA: 122256518
HAME: 121871085
PCLA: 123759647
PTRU: 123510504
EAF: 111709929
ISC: IscW_ISCW003150
DSV: 119442413
RSAN: 119386353
RMP: 119159511
VDE: 111243789 111245060
VJA: 111259800 111271998
TUT: 107360550
DPTE: 113792109
DFR: 124498931
CSCU: 111626639
PTEP: 107453371
SDM: 118191600
LGI: LOTGIDRAFT_141290
PCAN: 112564559
BGT: 106067245
GAE: 121380643
HRF: 124125393
HRJ: 124278151
CRG: 105340585
MYI: 110465124
PMAX: 117343252
MMER: 123533026
OBI: 106868905
OSN: 115219753
LAK: 106159379
OVI: T265_11520
PTM: GSPATT00035327001
 » show all
Reference
PMID:9662407
  Authors
Abdel-Majid RM, Leong WL, Schalkwyk LC, Smallman DS, Wong ST, Storm DR, Fine A, Dobson MJ, Guernsey DL, Neumann PE
  Title
Loss of adenylyl cyclase I activity disrupts patterning of mouse somatosensory cortex.
  Journal
Nat Genet 19:289-91 (1998)
DOI:10.1038/980
  Sequence
[mmu:432530]
Reference
PMID:8314585
  Authors
Villacres EC, Xia Z, Bookbinder LH, Edelhoff S, Disteche CM, Storm DR
  Title
Cloning, chromosomal mapping, and expression of human fetal brain type I adenylyl cyclase.
  Journal
Genomics 16:473-8 (1993)
DOI:10.1006/geno.1993.1213
  Sequence
[hsa:107]
LinkDB

KEGG   ORTHOLOGY: K08042
Entry
K08042                      KO                                     
Symbol
ADCY2
Name
adenylate cyclase 2 [EC:4.6.1.1]
Pathway
map00230  Purine metabolism
map01100  Metabolic pathways
map01522  Endocrine resistance
map04015  Rap1 signaling pathway
map04020  Calcium signaling pathway
map04022  cGMP-PKG signaling pathway
map04024  cAMP signaling pathway
map04062  Chemokine signaling pathway
map04072  Phospholipase D signaling pathway
map04114  Oocyte meiosis
map04211  Longevity regulating pathway
map04213  Longevity regulating pathway - multiple species
map04261  Adrenergic signaling in cardiomyocytes
map04270  Vascular smooth muscle contraction
map04371  Apelin signaling pathway
map04540  Gap junction
map04611  Platelet activation
map04713  Circadian entrainment
map04714  Thermogenesis
map04723  Retrograde endocannabinoid signaling
map04724  Glutamatergic synapse
map04725  Cholinergic synapse
map04727  GABAergic synapse
map04750  Inflammatory mediator regulation of TRP channels
map04911  Insulin secretion
map04912  GnRH signaling pathway
map04913  Ovarian steroidogenesis
map04914  Progesterone-mediated oocyte maturation
map04915  Estrogen signaling pathway
map04916  Melanogenesis
map04918  Thyroid hormone synthesis
map04921  Oxytocin signaling pathway
map04922  Glucagon signaling pathway
map04923  Regulation of lipolysis in adipocytes
map04925  Aldosterone synthesis and secretion
map04926  Relaxin signaling pathway
map04927  Cortisol synthesis and secretion
map04928  Parathyroid hormone synthesis, secretion and action
map04934  Cushing syndrome
map04935  Growth hormone synthesis, secretion and action
map04970  Salivary secretion
map04971  Gastric acid secretion
map04972  Pancreatic secretion
map04976  Bile secretion
map05032  Morphine addiction
map05163  Human cytomegalovirus infection
map05166  Human T-cell leukemia virus 1 infection
map05200  Pathways in cancer
map05207  Chemical carcinogenesis - receptor activation
map05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    K08042  ADCY2; adenylate cyclase 2
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    K08042  ADCY2; adenylate cyclase 2
   04371 Apelin signaling pathway
    K08042  ADCY2; adenylate cyclase 2
   04020 Calcium signaling pathway
    K08042  ADCY2; adenylate cyclase 2
   04072 Phospholipase D signaling pathway
    K08042  ADCY2; adenylate cyclase 2
   04024 cAMP signaling pathway
    K08042  ADCY2; adenylate cyclase 2
   04022 cGMP-PKG signaling pathway
    K08042  ADCY2; adenylate cyclase 2
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    K08042  ADCY2; adenylate cyclase 2
  09144 Cellular community - eukaryotes
   04540 Gap junction
    K08042  ADCY2; adenylate cyclase 2
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    K08042  ADCY2; adenylate cyclase 2
   04062 Chemokine signaling pathway
    K08042  ADCY2; adenylate cyclase 2
  09152 Endocrine system
   04911 Insulin secretion
    K08042  ADCY2; adenylate cyclase 2
   04922 Glucagon signaling pathway
    K08042  ADCY2; adenylate cyclase 2
   04923 Regulation of lipolysis in adipocytes
    K08042  ADCY2; adenylate cyclase 2
   04912 GnRH signaling pathway
    K08042  ADCY2; adenylate cyclase 2
   04913 Ovarian steroidogenesis
    K08042  ADCY2; adenylate cyclase 2
   04915 Estrogen signaling pathway
    K08042  ADCY2; adenylate cyclase 2
   04914 Progesterone-mediated oocyte maturation
    K08042  ADCY2; adenylate cyclase 2
   04921 Oxytocin signaling pathway
    K08042  ADCY2; adenylate cyclase 2
   04926 Relaxin signaling pathway
    K08042  ADCY2; adenylate cyclase 2
   04935 Growth hormone synthesis, secretion and action
    K08042  ADCY2; adenylate cyclase 2
   04918 Thyroid hormone synthesis
    K08042  ADCY2; adenylate cyclase 2
   04928 Parathyroid hormone synthesis, secretion and action
    K08042  ADCY2; adenylate cyclase 2
   04916 Melanogenesis
    K08042  ADCY2; adenylate cyclase 2
   04925 Aldosterone synthesis and secretion
    K08042  ADCY2; adenylate cyclase 2
   04927 Cortisol synthesis and secretion
    K08042  ADCY2; adenylate cyclase 2
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    K08042  ADCY2; adenylate cyclase 2
   04270 Vascular smooth muscle contraction
    K08042  ADCY2; adenylate cyclase 2
  09154 Digestive system
   04970 Salivary secretion
    K08042  ADCY2; adenylate cyclase 2
   04971 Gastric acid secretion
    K08042  ADCY2; adenylate cyclase 2
   04972 Pancreatic secretion
    K08042  ADCY2; adenylate cyclase 2
   04976 Bile secretion
    K08042  ADCY2; adenylate cyclase 2
  09156 Nervous system
   04724 Glutamatergic synapse
    K08042  ADCY2; adenylate cyclase 2
   04727 GABAergic synapse
    K08042  ADCY2; adenylate cyclase 2
   04725 Cholinergic synapse
    K08042  ADCY2; adenylate cyclase 2
   04723 Retrograde endocannabinoid signaling
    K08042  ADCY2; adenylate cyclase 2
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    K08042  ADCY2; adenylate cyclase 2
  09149 Aging
   04211 Longevity regulating pathway
    K08042  ADCY2; adenylate cyclase 2
   04213 Longevity regulating pathway - multiple species
    K08042  ADCY2; adenylate cyclase 2
  09159 Environmental adaptation
   04713 Circadian entrainment
    K08042  ADCY2; adenylate cyclase 2
   04714 Thermogenesis
    K08042  ADCY2; adenylate cyclase 2
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K08042  ADCY2; adenylate cyclase 2
   05207 Chemical carcinogenesis - receptor activation
    K08042  ADCY2; adenylate cyclase 2
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K08042  ADCY2; adenylate cyclase 2
   05163 Human cytomegalovirus infection
    K08042  ADCY2; adenylate cyclase 2
  09165 Substance dependence
   05032 Morphine addiction
    K08042  ADCY2; adenylate cyclase 2
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    K08042  ADCY2; adenylate cyclase 2
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    K08042  ADCY2; adenylate cyclase 2
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    K08042  ADCY2; adenylate cyclase 2
Enzymes [BR:ko01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     K08042  ADCY2; adenylate cyclase 2
Other DBs
RN: R00089 R00434
GO: 0004016
Genes
HSA: 108(ADCY2)
PTR: 100608010(ADCY2)
PPS: 100992014(ADCY2)
GGO: 101141389(ADCY2)
PON: 100445431(ADCY2)
NLE: 100600367(ADCY2)
MCC: 695328(ADCY2)
MCF: 102130114(ADCY2)
CSAB: 103214981(ADCY2)
CATY: 105585972(ADCY2)
PANU: 101006754(ADCY2)
TGE: 112625956(ADCY2)
RRO: 104674083(ADCY2)
RBB: 108536960(ADCY2)
TFN: 117064735(ADCY2)
PTEH: 111546755(ADCY2)
CJC: 100385658(ADCY2)
SBQ: 101043334(ADCY2)
CSYR: 103252919(ADCY2)
MMUR: 105859934(ADCY2)
OGA: 100941250(ADCY2)
MMU: 210044(Adcy2)
MCAL: 110307661(Adcy2)
MPAH: 110328764(Adcy2)
RNO: 81636(Adcy2)
MCOC: 116083593(Adcy2)
MUN: 110550962
CGE: 100773811(Adcy2)
PLEU: 114696121(Adcy2)
NGI: 103735350(Adcy2)
HGL: 101718304(Adcy2)
CPOC: 100731999(Adcy2)
CCAN: 109695818(Adcy2)
DORD: 105983849(Adcy2)
DSP: 122120987(Adcy2)
OCU: 100009201(ADCY2)
OPI: 101528674(ADCY2)
TUP: 102492353(ADCY2)
CFA: 478624(ADCY2)
VVP: 112934273(ADCY2)
VLG: 121477531(ADCY2)
AML: 100473195(ADCY2)
UMR: 103679250(ADCY2)
UAH: 113260807(ADCY2)
UAR: 123791264(ADCY2)
ELK: 111153427
LLV: 125099871
MPUF: 101674868(ADCY2)
ORO: 101365382(ADCY2)
EJU: 114223681(ADCY2)
ZCA: 113929853(ADCY2)
MLX: 118006264(ADCY2)
FCA: 101094327(ADCY2)
PYU: 121042416(ADCY2)
PBG: 122495529(ADCY2)
PTG: 102949732(ADCY2)
PPAD: 109267830(ADCY2)
AJU: 106971248(ADCY2)
HHV: 120225093(ADCY2)
BTA: 510708(ADCY2)
BOM: 102274117(ADCY2)
BIU: 109574822(ADCY2)
BBUB: 102412622(ADCY2)
CHX: 102171922(ADCY2)
OAS: 101102089(ADCY2)
ODA: 120879368(ADCY2)
CCAD: 122454210(ADCY2)
SSC: 100517503(ADCY2)
CFR: 102510993(ADCY2)
CBAI: 105081234(ADCY2)
CDK: 105094039(ADCY2)
VPC: 102539698(ADCY2)
BACU: 103020085(ADCY2)
LVE: 103084817(ADCY2)
OOR: 101286207(ADCY2)
DLE: 111178556(ADCY2)
PCAD: 102991224(ADCY2)
PSIU: 116752275(ADCY2)
ECB: 100071337(ADCY2)
EPZ: 103562505
EAI: 106823001(ADCY2)
MYB: 102260356(ADCY2)
MYD: 102774384(ADCY2)
MMYO: 118656192(ADCY2)
MLF: 102430354(ADCY2)
MNA: 107540528(ADCY2)
PKL: 118703044(ADCY2)
HAI: 109375976(ADCY2)
DRO: 112321008(ADCY2)
SHON: 118998674(ADCY2)
AJM: 119049317(ADCY2)
PDIC: 114508056(ADCY2)
PHAS: 123824963(ADCY2)
MMF: 118642779(ADCY2)
RFQ: 117025090(ADCY2)
PALE: 102893265(ADCY2)
PGIG: 120586284(ADCY2)
PVP: 105299581(ADCY2)
RAY: 107502700(ADCY2)
TOD: 119260631(ADCY2)
SARA: 101539413(ADCY2)
LAV: 100673570(ADCY2)
TMU: 101360334
MDO: 100013164(ADCY2)
GAS: 123252650(ADCY2)
SHR: 100922434(ADCY2)
PCW: 110220436(ADCY2)
OAA: 100089708(ADCY2)
GGA: 420935(ADCY2)
PCOC: 116226507(ADCY2)
MGP: 100540738(ADCY2)
CJO: 107309543(ADCY2)
NMEL: 110394300(ADCY2)
APLA: 101803512(ADCY2)
ACYG: 106036531(ADCY2)
TGU: 100223820(ADCY2)
LSR: 110479527(ADCY2)
SCAN: 103815408(ADCY2)
PMOA: 120504898(ADCY2)
OTC: 121339726(ADCY2)
PRUF: 121358032(ADCY2)
GFR: 102038853(ADCY2)
FAB: 101808400(ADCY2)
PHI: 102113898(ADCY2)
PMAJ: 107199935(ADCY2)
CCAE: 111925673(ADCY2)
CCW: 104685925(ADCY2)
ETL: 114055132(ADCY2)
ZAB: 102072826(ADCY2)
FPG: 101911647(ADCY2)
FCH: 102049688(ADCY2)
CLV: 102097532(ADCY2)
EGZ: 104126191(ADCY2)
NNI: 104018888(ADCY2)
ACUN: 113476067(ADCY2)
TALA: 104359690(ADCY2)
PADL: 103915154(ADCY2)
ACHC: 115353041(ADCY2)
AAM: 106492356(ADCY2)
AROW: 112974051(ADCY2)
NPD: 112955254(ADCY2)
DNE: 112982724(ADCY2)
ASN: 102383838(ADCY2)
AMJ: 102562034(ADCY2)
CPOO: 109314286(ADCY2)
GGN: 109298362(ADCY2)
PSS: 102444057(ADCY2)
CMY: 102930552(ADCY2)
CPIC: 101952054(ADCY2)
TST: 117872756
CABI: 116828360(ADCY2)
MRV: 120397653(ADCY2)
ACS: 100555265(adcy2)
PVT: 110089596
SUND: 121929529(ADCY2)
PBI: 103050340(ADCY2)
PMUR: 107297625(ADCY2)
TSR: 106545186
PGUT: 117662380(ADCY2)
VKO: 123029667(ADCY2)
PMUA: 114601220(ADCY2)
ZVI: 118077623(ADCY2)
GJA: 107108835(ADCY2)
DRE: 557902(adcy2b) 563724(adcy2a)
SRX: 107711297 107746972 107751899 107754795(adcy2)
SANH: 107664610 107691497 107694336
SGH: 107551198 107584338(adcy2) 107595616
CCAR: 109066542 109086675
CAUA: 113090787 113116166 113119536
IPU: 108272199(adcy2a) 108272792(adcy2b)
PHYP: 113534051 113543796
SMEO: 124381992(adcy2b) 124384555(adcy2a)
AMEX: 103036916 103043428
EEE: 113578463 113590334
TRU: 101074943 101077175
TNG: GSTEN00005702G001 GSTEN00007551G001 GSTEN00017582G001
LCO: 104933548 104936739 104940420
NCC: 104952475 104962256(adcy2)
CGOB: 115020798(adcy2)
ELY: 117263948(adcy2b) 117265672(adcy2a)
PLEP: 121946261(adcy2a) 121957695(adcy2b)
SLUC: 116041211(adcy2b) 116049201(adcy2a)
ECRA: 117946352(adcy2a) 117957152(adcy2b)
PFLV: 114556982 114568098(adcy2)
GAT: 120810605(adcy2a) 120822048 120826532
PPUG: 119197448(adcy2a) 119219461
MSAM: 119897894(adcy2a) 119907366(adcy2b)
CUD: 121513506(adcy2a) 121524111(adcy2b)
MZE: 101464825 101472004 101474342
ONL: 100693919 100706736(adcy2) 100707801
OAU: 116313447(adcy2b) 116329362(adcy2a)
OLA: 101159207 101172459
OML: 112136286(adcy2b) 112143511(adcy2a)
XMA: 102219843 102225654
XCO: 114141804 114156097(adcy2)
XHE: 116717194 116731245
PRET: 103472071 103478370
PFOR: 103146018 103151564
PLAI: 106949352 106961924(adcy2)
PMEI: 106922633 106926897
GAF: 122831188(adcy2a) 122844085(adcy2b)
CVG: 107084393 107091823(adcy2)
CTUL: 119791316(adcy2a) 119792954(adcy2b)
GMU: 124865559(adcy2a) 124879381(adcy2b)
NFU: 107376988 107378756 107383184
KMR: 108232311(adcy2a) 108238708(adcy2b)
ALIM: 106514248 106516755
NWH: 119410353(adcy2a) 119425622(adcy2b)
AOCE: 111562440 111573422(adcy2) 111585533
CSEM: 103388319 103394729
POV: 109631507(adcy2) 109632042
SSEN: 122774912(adcy2a) 122786587(adcy2b)
HHIP: 117770401(adcy2b) 117777130(adcy2a)
LCF: 108889001 108900397
SDU: 111227902 111233172 111238586
SLAL: 111655934 111661694 111671420(adcy2)
XGL: 120783631(adcy2a) 120786774(adcy2b)
HCQ: 109508262 109521934(adcy2)
BPEC: 110167228 110171614
MALB: 109958353 109971723
SASA: 106570343 106588693
OTW: 112229303(adcy2b) 112265839
OMY: 110489405 110496472
OGO: 124027005 124043321(adcy2b)
ONE: 115128595
SALP: 111954801(adcy2) 111955524
SNH: 120022775 120027455
ELS: 105012408(adcy2)
SFM: 108919207(adcy2) 108930627 108940527 114911923
PKI: 111844387 111852779
AANG: 118225550(adcy2a) 118234313(adcy2b)
LOC: 102696921(adcy2)
PSPA: 121309305 121314788
ARUT: 117394673 117399819
LCM: 102365947 102367170
CMK: 103183192
RTP: 109920424(adcy2)
BFO: 118417332
BBEL: 109481983
SPU: 575180
APLC: 110980095
SKO: 102803250
DME: Dmel_CG7978(Ac76E)
DER: 6545709
DSE: 6619425
DSI: Dsimw501_GD14841(Dsim_GD14841)
DYA: Dyak_GE19638 Dyak_GE27856
DAN: 6506248
DSR: 110189922
DPO: Dpse_GA20737
DPE: 6599071
DMN: 108152507
DWI: 6638793
DGR: 6557116
DMO: Dmoj_GI11655
DAZ: 108614292
DNV: 108651863
DHE: 111604449
DVI: 6622821
CCAT: 101458244
BOD: 106621071
MDE: 101893904
SCAC: 106091398
LCQ: 111683625
AGA: AgaP_AGAP010436
ACOZ: 120955519
AARA: 120900861
AAG: 5571159
AALB: 109418769
CQU: CpipJ_CPIJ004739
CPII: 120425270
CNS: 116340485
AME: 552216
ACER: 107992970
ALAB: 122713476
BIM: 100745521
BBIF: 117207730
BVK: 117238217
BVAN: 117159965
BTER: 100647623
BPYO: 122570472
CCAL: 108631101
OBB: 114880740
MGEN: 117228009
NMEA: 116428151
CGIG: 122404122
SOC: 105197184
MPHA: 105835065
AEC: 105143483
ACEP: 105617405
PBAR: 105425936
VEM: 105559069
HST: 105184375
DQU: 106746346
CFO: 105250746
FEX: 115233348
LHU: 105670932
PGC: 109855918
OBO: 105285379
PCF: 106792130
PFUC: 122526144
VPS: 122635235
NVI: 100118148
CSOL: 105367877
TPRE: 106651693
MDL: 103577402
CGLO: 123264131
FAS: 105265325
DAM: 107046806
AGIF: 122851073
CCIN: 107263506 107267175
TCA: 660403
DPA: 109533154 109543965
SOY: 115878992 115885861
ATD: 109608976
CSET: 123309201 123314494
AGB: 108913278 108915947
LDC: 111507767
NVL: 108567526
APLN: 108733663 108742235
PPYR: 116174497 116175132
OTU: 111424772
BMOR: 101737606
BMAN: 114243277
MSEX: 115452886
DPL: KGM_212333
BANY: 112043432
PMAC: 106718962
PPOT: 106100281
PXU: 106121310
PRAP: 110995397
ZCE: 119840764
HAW: 110373694
TNL: 113497935
OFU: 114363060
PXY: 105382235 105385761
API: 100164066
DNX: 107167195
AGS: 114123846
RMD: 113553384
BTAB: 109030143
DCI: 103508920
CLEC: 106667432
HHAL: 106691350
NLU: 111045768
PHU: Phum_PHUM294440
ZNE: 110829129
CSEC: 111868923
FCD: 110849688
PVM: 113818924
PJA: 122256199 122266929
HAME: 121867730 121880075
PCLA: 123770600 123773323
PTRU: 123501259 123519945
HAZT: 108664914 108670249
DSV: 119436082
RSAN: 119372661
RMP: 119185511
VDE: 111251320
VJA: 111272620
TUT: 107363859 107367509
DPTE: 113791828 113798730
DFR: 124490750 124491170
CSCU: 111623407 111638684
PTEP: 107452662
SDM: 118186485 118187008
LGI: LOTGIDRAFT_115371
PCAN: 112577004
BGT: 106067294
GAE: 121388686
HRF: 124135295
HRJ: 124266340
CRG: 105336030
MYI: 110458458
PMAX: 117337564
MMER: 123549315
LAK: 106151524 106156374
TAD: TRIADDRAFT_52497
AQU: 100636322 100636336
 » show all
Reference
PMID:1427768
  Authors
Stengel D, Parma J, Gannage MH, Roeckel N, Mattei MG, Barouki R, Hanoune J
  Title
Different chromosomal localization of two adenylyl cyclase genes expressed in human brain.
  Journal
Hum Genet 90:126-30 (1992)
DOI:10.1007/BF00210755
  Sequence
[hsa:108]
Reference
PMID:22461431
  Authors
Hardin M, Zielinski J, Wan ES, Hersh CP, Castaldi PJ, Schwinder E, Hawrylkiewicz I, Sliwinski P, Cho MH, Silverman EK
  Title
CHRNA3/5, IREB2, and ADCY2 are associated with severe chronic obstructive pulmonary disease in Poland.
  Journal
Am J Respir Cell Mol Biol 47:203-8 (2012)
DOI:10.1165/rcmb.2012-0011OC
LinkDB

KEGG   ORTHOLOGY: K08043
Entry
K08043                      KO                                     
Symbol
ADCY3
Name
adenylate cyclase 3 [EC:4.6.1.1]
Pathway
map00230  Purine metabolism
map01100  Metabolic pathways
map01522  Endocrine resistance
map04015  Rap1 signaling pathway
map04020  Calcium signaling pathway
map04022  cGMP-PKG signaling pathway
map04024  cAMP signaling pathway
map04062  Chemokine signaling pathway
map04072  Phospholipase D signaling pathway
map04114  Oocyte meiosis
map04211  Longevity regulating pathway
map04213  Longevity regulating pathway - multiple species
map04261  Adrenergic signaling in cardiomyocytes
map04270  Vascular smooth muscle contraction
map04371  Apelin signaling pathway
map04540  Gap junction
map04611  Platelet activation
map04713  Circadian entrainment
map04714  Thermogenesis
map04723  Retrograde endocannabinoid signaling
map04724  Glutamatergic synapse
map04725  Cholinergic synapse
map04727  GABAergic synapse
map04740  Olfactory transduction
map04750  Inflammatory mediator regulation of TRP channels
map04911  Insulin secretion
map04912  GnRH signaling pathway
map04913  Ovarian steroidogenesis
map04914  Progesterone-mediated oocyte maturation
map04915  Estrogen signaling pathway
map04916  Melanogenesis
map04918  Thyroid hormone synthesis
map04921  Oxytocin signaling pathway
map04923  Regulation of lipolysis in adipocytes
map04925  Aldosterone synthesis and secretion
map04926  Relaxin signaling pathway
map04927  Cortisol synthesis and secretion
map04928  Parathyroid hormone synthesis, secretion and action
map04934  Cushing syndrome
map04935  Growth hormone synthesis, secretion and action
map04962  Vasopressin-regulated water reabsorption
map04970  Salivary secretion
map04971  Gastric acid secretion
map04972  Pancreatic secretion
map04976  Bile secretion
map05032  Morphine addiction
map05110  Vibrio cholerae infection
map05163  Human cytomegalovirus infection
map05166  Human T-cell leukemia virus 1 infection
map05200  Pathways in cancer
map05207  Chemical carcinogenesis - receptor activation
map05414  Dilated cardiomyopathy
Disease
H02106  Genetic obesity
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    K08043  ADCY3; adenylate cyclase 3
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    K08043  ADCY3; adenylate cyclase 3
   04371 Apelin signaling pathway
    K08043  ADCY3; adenylate cyclase 3
   04020 Calcium signaling pathway
    K08043  ADCY3; adenylate cyclase 3
   04072 Phospholipase D signaling pathway
    K08043  ADCY3; adenylate cyclase 3
   04024 cAMP signaling pathway
    K08043  ADCY3; adenylate cyclase 3
   04022 cGMP-PKG signaling pathway
    K08043  ADCY3; adenylate cyclase 3
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    K08043  ADCY3; adenylate cyclase 3
  09144 Cellular community - eukaryotes
   04540 Gap junction
    K08043  ADCY3; adenylate cyclase 3
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    K08043  ADCY3; adenylate cyclase 3
   04062 Chemokine signaling pathway
    K08043  ADCY3; adenylate cyclase 3
  09152 Endocrine system
   04911 Insulin secretion
    K08043  ADCY3; adenylate cyclase 3
   04923 Regulation of lipolysis in adipocytes
    K08043  ADCY3; adenylate cyclase 3
   04912 GnRH signaling pathway
    K08043  ADCY3; adenylate cyclase 3
   04913 Ovarian steroidogenesis
    K08043  ADCY3; adenylate cyclase 3
   04915 Estrogen signaling pathway
    K08043  ADCY3; adenylate cyclase 3
   04914 Progesterone-mediated oocyte maturation
    K08043  ADCY3; adenylate cyclase 3
   04921 Oxytocin signaling pathway
    K08043  ADCY3; adenylate cyclase 3
   04926 Relaxin signaling pathway
    K08043  ADCY3; adenylate cyclase 3
   04935 Growth hormone synthesis, secretion and action
    K08043  ADCY3; adenylate cyclase 3
   04918 Thyroid hormone synthesis
    K08043  ADCY3; adenylate cyclase 3
   04928 Parathyroid hormone synthesis, secretion and action
    K08043  ADCY3; adenylate cyclase 3
   04916 Melanogenesis
    K08043  ADCY3; adenylate cyclase 3
   04925 Aldosterone synthesis and secretion
    K08043  ADCY3; adenylate cyclase 3
   04927 Cortisol synthesis and secretion
    K08043  ADCY3; adenylate cyclase 3
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    K08043  ADCY3; adenylate cyclase 3
   04270 Vascular smooth muscle contraction
    K08043  ADCY3; adenylate cyclase 3
  09154 Digestive system
   04970 Salivary secretion
    K08043  ADCY3; adenylate cyclase 3
   04971 Gastric acid secretion
    K08043  ADCY3; adenylate cyclase 3
   04972 Pancreatic secretion
    K08043  ADCY3; adenylate cyclase 3
   04976 Bile secretion
    K08043  ADCY3; adenylate cyclase 3
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    K08043  ADCY3; adenylate cyclase 3
  09156 Nervous system
   04724 Glutamatergic synapse
    K08043  ADCY3; adenylate cyclase 3
   04727 GABAergic synapse
    K08043  ADCY3; adenylate cyclase 3
   04725 Cholinergic synapse
    K08043  ADCY3; adenylate cyclase 3
   04723 Retrograde endocannabinoid signaling
    K08043  ADCY3; adenylate cyclase 3
  09157 Sensory system
   04740 Olfactory transduction
    K08043  ADCY3; adenylate cyclase 3
   04750 Inflammatory mediator regulation of TRP channels
    K08043  ADCY3; adenylate cyclase 3
  09149 Aging
   04211 Longevity regulating pathway
    K08043  ADCY3; adenylate cyclase 3
   04213 Longevity regulating pathway - multiple species
    K08043  ADCY3; adenylate cyclase 3
  09159 Environmental adaptation
   04713 Circadian entrainment
    K08043  ADCY3; adenylate cyclase 3
   04714 Thermogenesis
    K08043  ADCY3; adenylate cyclase 3
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K08043  ADCY3; adenylate cyclase 3
   05207 Chemical carcinogenesis - receptor activation
    K08043  ADCY3; adenylate cyclase 3
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K08043  ADCY3; adenylate cyclase 3
   05163 Human cytomegalovirus infection
    K08043  ADCY3; adenylate cyclase 3
  09171 Infectious disease: bacterial
   05110 Vibrio cholerae infection
    K08043  ADCY3; adenylate cyclase 3
  09165 Substance dependence
   05032 Morphine addiction
    K08043  ADCY3; adenylate cyclase 3
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    K08043  ADCY3; adenylate cyclase 3
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    K08043  ADCY3; adenylate cyclase 3
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    K08043  ADCY3; adenylate cyclase 3
Enzymes [BR:ko01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     K08043  ADCY3; adenylate cyclase 3
Other DBs
RN: R00089 R00434
GO: 0008294
Genes
HSA: 109(ADCY3)
PTR: 459070(ADCY3)
PPS: 100995134(ADCY3)
GGO: 101144031(ADCY3)
PON: 100431221(ADCY3)
NLE: 100586735(ADCY3)
MCC: 693523(ADCY3)
MCF: 101925741(ADCY3)
CSAB: 103220665(ADCY3)
CATY: 105578529(ADCY3)
PANU: 101006469(ADCY3)
TGE: 112604540(ADCY3)
RRO: 104658457(ADCY3)
RBB: 108543021(ADCY3)
TFN: 117062665(ADCY3)
PTEH: 111554419(ADCY3)
CJC: 100415165(ADCY3)
SBQ: 101040601(ADCY3)
CSYR: 103262642(ADCY3)
MMUR: 105884349(ADCY3)
OGA: 100942592(ADCY3)
MMU: 104111(Adcy3)
MCAL: 110306494(Adcy3)
MPAH: 110324646(Adcy3)
RNO: 64508(Adcy3)
MCOC: 116079663(Adcy3)
MUN: 110555185(Adcy3)
CGE: 100770498(Adcy3)
PLEU: 114697107(Adcy3)
NGI: 103746460(Adcy3)
HGL: 101713887(Adcy3)
CPOC: 100725667(Adcy3)
CCAN: 109685686(Adcy3)
DORD: 105983683(Adcy3)
DSP: 122122500(Adcy3)
OCU: 100343958(ADCY3)
OPI: 101529277(ADCY3)
TUP: 102477532(ADCY3)
CFA: 482994(ADCY3)
VVP: 112908545(ADCY3)
VLG: 121491160(ADCY3)
AML: 100471164(ADCY3)
UMR: 103671685(ADCY3)
UAH: 113270586(ADCY3)
UAR: 123799951(ADCY3)
ELK: 111154044
LLV: 125108687
MPUF: 101671296(ADCY3)
ORO: 101368682(ADCY3)
EJU: 114205853(ADCY3)
ZCA: 113937275(ADCY3)
MLX: 118007652(ADCY3)
FCA: 101088157(ADCY3)
PYU: 121044199(ADCY3)
PBG: 122497386(ADCY3)
PPAD: 109267527(ADCY3)
AJU: 106989109(ADCY3)
HHV: 120235801(ADCY3)
BTA: 535603(ADCY3)
BOM: 102282732(ADCY3)
BIU: 109566330(ADCY3)
BBUB: 102407976(ADCY3)
CHX: 102169019(ADCY3)
OAS: 101108203(ADCY3)
ODA: 120851596(ADCY3)
CCAD: 122441999(ADCY3)
SSC: 100514402(ADCY3)
CFR: 102512950(ADCY3)
CBAI: 105063873(ADCY3)
CDK: 105100030(ADCY3)
VPC: 102536207(ADCY3)
BACU: 103020845(ADCY3)
LVE: 103076182(ADCY3)
OOR: 101283651(ADCY3)
DLE: 111175000(ADCY3)
PCAD: 102989136(ADCY3)
PSIU: 116764233(ADCY3)
ECB: 100055961(ADCY3)
EPZ: 103547823(ADCY3)
EAI: 106841140(ADCY3)
MYB: 102261014(ADCY3)
MYD: 102757252(ADCY3)
MMYO: 118669221(ADCY3)
MLF: 102442682(ADCY3)
MNA: 107534062(ADCY3)
PKL: 118717241(ADCY3)
HAI: 109385186(ADCY3)
DRO: 112297750(ADCY3)
SHON: 119001392(ADCY3)
AJM: 119050413(ADCY3)
PDIC: 114500049(ADCY3)
PHAS: 123822448(ADCY3)
MMF: 118630645(ADCY3)
RFQ: 117032856(ADCY3)
PALE: 102886232(ADCY3)
PGIG: 120621545(ADCY3)
PVP: 105289813(ADCY3)
RAY: 107498506(ADCY3)
MJV: 108397345(ADCY3)
TOD: 119259500(ADCY3)
SARA: 101547055(ADCY3)
LAV: 100674724(ADCY3)
TMU: 101349290
DNM: 101411573(ADCY3)
MDO: 100025332(ADCY3)
GAS: 123235004(ADCY3)
SHR: 100925657(ADCY3)
PCW: 110206523(ADCY3)
OAA: 100085901(ADCY3)
GGA: 422013(ADCY3)
PCOC: 116235620(ADCY3)
MGP: 100538467(ADCY3)
CJO: 107312346(ADCY3)
NMEL: 110395965(ADCY3)
APLA: 101791112(ADCY3)
AFUL: 116488201(ADCY3)
PMOA: 120504513(ADCY3)
FPG: 101921567(ADCY3)
FCH: 102047195(ADCY3)
CLV: 102092425(ADCY3)
EGZ: 104132021(ADCY3)
NNI: 104014763(ADCY3)
ACUN: 113478856(ADCY3)
TALA: 116958839(ADCY3)
ACHC: 115351414(ADCY3)
AROW: 112966650(ADCY3)
NPD: 112948757(ADCY3)
DNE: 112984267(ADCY3)
ASN: 102374249(ADCY3)
AMJ: 102566746(ADCY3)
CPOO: 109311539(ADCY3)
PSS: 102463305(ADCY3)
CMY: 102941584(ADCY3)
CPIC: 101948171(ADCY3)
TST: 117875434(ADCY3)
CABI: 116830876(ADCY3)
MRV: 120401447(ADCY3)
ACS: 100558229(adcy3)
PVT: 110089954(ADCY3)
SUND: 121919215(ADCY3)
PMUR: 107284867(ADCY3)
TSR: 106555200(ADCY3)
PGUT: 117667701(ADCY3)
PMUA: 114594931
ZVI: 118082958(ADCY3)
GJA: 107124706(ADCY3)
XLA: 108717252(adcy3.L) 108718304
XTR: 100038110(dnajc27)
NPR: 108795542(ADCY3)
RTEM: 120936026(ADCY3)
BBUF: 120997161(ADCY3)
BGAR: 122935174(ADCY3)
DRE: 571825(adcy3a)
SRX: 107708319
SANH: 107685373 107688975 107703925
SGH: 107593287 107598935(adcy3)
CCAR: 109061725 109090165
CAUA: 113059808 113097331 113116527 113120648
IPU: 108271861(adcy3a)
PHYP: 113526734(adcy3)
SMEO: 124385054(adcy3a)
AMEX: 103027936(adcy3) 103034748
EEE: 113583134(adcy3)
TRU: 101066423(adcy3)
TNG: GSTEN00021989G001
LCO: 104938398
NCC: 104945720
CGOB: 115003477 115021083
ELY: 117264741(adcy3a)
PLEP: 121945854(adcy3a)
SLUC: 116066597
ECRA: 117946038(adcy3a) 117961136
PFLV: 114557128 114572936
GAT: 120810053(adcy3a)
PPUG: 119194580 119197445(adcy3a)
MSAM: 119896893(adcy3a)
CUD: 121513070(adcy3a)
MZE: 101468640
ONL: 100710007
OAU: 116316197(adcy3a)
OLA: 101167167 105355856(adcy3)
OML: 112151984
XMA: 102219355(adcy3)
XCO: 114152719(adcy3)
XHE: 116717093(adcy3)
PRET: 103478767(adcy3)
PFOR: 103139954(adcy3) 103144118
PLAI: 106937126(adcy3) 106957331
PMEI: 106920589(adcy3) 106920816
GAF: 122831106(adcy3a)
CTUL: 119792159(adcy3a)
GMU: 124865677(adcy3a) 124882389
NFU: 107378974(adcy3)
KMR: 108247740(adcy3a)
ALIM: 106530667
NWH: 119410425 119418144
AOCE: 111578872 111588972
CSEM: 103388741(adcy3)
POV: 109632037(adcy3)
SSEN: 122774154(adcy3a)
HHIP: 117758850 117777341(adcy3a)
LCF: 108886083
SDU: 111227842
SLAL: 111664165
XGL: 120783866(adcy3a)
HCQ: 109521893(adcy3)
BPEC: 110159121(adcy3)
MALB: 109952263
SASA: 106584132 106605024 106607897
OTW: 112223172 112234013
OMY: 110490105 110519325(adcy3a) 110522313
OGO: 123995167 123997492 124005714
ONE: 115106654 115139332 115141418
SALP: 111972593 112069658(adcy3)
SNH: 120019516 120031336 120048257
ELS: 105005964(adcy3)
SFM: 108929094(adcy3)
PKI: 111851542
AANG: 118207103(adcy3a) 118228793
LOC: 102683703(adcy3)
PSPA: 121316002(adcy3a)
ARUT: 117403044(adcy3a)
RTP: 109935189(adcy3)
BFO: 118404575
BBEL: 109476282
SPU: 582454
APLC: 110978247
DME: Dmel_CG1506(Ac3)
DER: 6548790
DSE: 6619304
DSI: Dsimw501_GD29214(Dsim_GD29214)
DYA: Dyak_GE12923
DAN: 6498294
DSR: 110185021
DPO: Dpse_GA13464
DPE: 6593540
DMN: 108163161
DWI: 6644450
DGR: 6562956
DMO: Dmoj_GI17441
DAZ: 108610471
DNV: 108658095
DHE: 111592509
DVI: 6628564
CCAT: 101452921
BOD: 106627089
MDE: 101889515
SCAC: 106084968
LCQ: 111674541
AGA: AgaP_AGAP009315
ACOZ: 120955699
AARA: 120900035
AAG: 5571858
AALB: 115265620
CQU: CpipJ_CPIJ007058
CPII: 120422382
CNS: 116337149
AME: 408363(Ac3)
ACER: 107995067
ALAB: 122718105
BIM: 100743487
BBIF: 117214055
BVK: 117236364
BVAN: 117161479
BTER: 100651573
BPYO: 122572716
CCAL: 108626049
OBB: 114872430
MGEN: 117225471
NMEA: 116434955
CGIG: 122404482
SOC: 105201589
MPHA: 105830745
AEC: 105143828
ACEP: 105620050
PBAR: 105427823
VEM: 105567376
HST: 105189653
DQU: 106743434
CFO: 105258159
FEX: 115245547
LHU: 105678451
PGC: 109856042
OBO: 105275628
PCF: 106784577
PFUC: 122517070
VPS: 122627953
NVI: 100122644
CSOL: 105368022
TPRE: 106659602
MDL: 103570576
CGLO: 123262566
FAS: 105269461
DAM: 107048673
AGIF: 122853229
CCIN: 107266397
TCA: 657568
DPA: 109535556
SOY: 115890718
ATD: 109599040
CSET: 123312147
AGB: 111692202
LDC: 111511084
NVL: 108559187
APLN: 108740017
PPYR: 116170321
OTU: 111419645
BMOR: 105842081
MSEX: 115441032
BANY: 112058553
PPOT: 106099456
PXU: 106127520
PRAP: 110998659
ZCE: 119834210
OFU: 114364732
PXY: 105387232
API: 100163190
DNX: 107161386
AGS: 114126436
RMD: 113555842
BTAB: 109035248
CLEC: 106670646
HHAL: 106679676
NLU: 111048874
PHU: Phum_PHUM149090
FOC: 113214623
ZNE: 110830923
CSEC: 117282028
FCD: 110846307
DPX: DAPPUDRAFT_317298
DMK: 116928509
PJA: 122262922
HAME: 121867312
PCLA: 123764295
PTRU: 123503561
HAZT: 108664322
DSV: 119449210
RSAN: 119384145
RMP: 119169944
VDE: 111252385
VJA: 111263764
TUT: 107366670
DPTE: 113791730
DFR: 124494734
CSCU: 111621814
PTEP: 107455365
SDM: 118187632
BGT: 106067539
GAE: 121388074
HRF: 124147700
HRJ: 124282634
CRG: 105328828
NVE: 5514741
ATEN: 116286473
XEN: 124433348
TAD: TRIADDRAFT_58375
 » show all
Reference
PMID:2255909
  Authors
Bakalyar HA, Reed RR
  Title
Identification of a specialized adenylyl cyclase that may mediate odorant detection.
  Journal
Science 250:1403-6 (1990)
DOI:10.1126/science.2255909
  Sequence
[rno:64508]
LinkDB

KEGG   ORTHOLOGY: K08044
Entry
K08044                      KO                                     
Symbol
ADCY4
Name
adenylate cyclase 4 [EC:4.6.1.1]
Pathway
map00230  Purine metabolism
map01100  Metabolic pathways
map01522  Endocrine resistance
map04015  Rap1 signaling pathway
map04020  Calcium signaling pathway
map04022  cGMP-PKG signaling pathway
map04024  cAMP signaling pathway
map04062  Chemokine signaling pathway
map04072  Phospholipase D signaling pathway
map04114  Oocyte meiosis
map04211  Longevity regulating pathway
map04213  Longevity regulating pathway - multiple species
map04261  Adrenergic signaling in cardiomyocytes
map04270  Vascular smooth muscle contraction
map04371  Apelin signaling pathway
map04540  Gap junction
map04611  Platelet activation
map04713  Circadian entrainment
map04714  Thermogenesis
map04723  Retrograde endocannabinoid signaling
map04724  Glutamatergic synapse
map04725  Cholinergic synapse
map04727  GABAergic synapse
map04742  Taste transduction
map04750  Inflammatory mediator regulation of TRP channels
map04911  Insulin secretion
map04912  GnRH signaling pathway
map04913  Ovarian steroidogenesis
map04914  Progesterone-mediated oocyte maturation
map04915  Estrogen signaling pathway
map04916  Melanogenesis
map04918  Thyroid hormone synthesis
map04921  Oxytocin signaling pathway
map04923  Regulation of lipolysis in adipocytes
map04925  Aldosterone synthesis and secretion
map04926  Relaxin signaling pathway
map04927  Cortisol synthesis and secretion
map04928  Parathyroid hormone synthesis, secretion and action
map04934  Cushing syndrome
map04935  Growth hormone synthesis, secretion and action
map04970  Salivary secretion
map04971  Gastric acid secretion
map04972  Pancreatic secretion
map04976  Bile secretion
map05032  Morphine addiction
map05163  Human cytomegalovirus infection
map05166  Human T-cell leukemia virus 1 infection
map05200  Pathways in cancer
map05207  Chemical carcinogenesis - receptor activation
map05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    K08044  ADCY4; adenylate cyclase 4
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    K08044  ADCY4; adenylate cyclase 4
   04371 Apelin signaling pathway
    K08044  ADCY4; adenylate cyclase 4
   04020 Calcium signaling pathway
    K08044  ADCY4; adenylate cyclase 4
   04072 Phospholipase D signaling pathway
    K08044  ADCY4; adenylate cyclase 4
   04024 cAMP signaling pathway
    K08044  ADCY4; adenylate cyclase 4
   04022 cGMP-PKG signaling pathway
    K08044  ADCY4; adenylate cyclase 4
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    K08044  ADCY4; adenylate cyclase 4
  09144 Cellular community - eukaryotes
   04540 Gap junction
    K08044  ADCY4; adenylate cyclase 4
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    K08044  ADCY4; adenylate cyclase 4
   04062 Chemokine signaling pathway
    K08044  ADCY4; adenylate cyclase 4
  09152 Endocrine system
   04911 Insulin secretion
    K08044  ADCY4; adenylate cyclase 4
   04923 Regulation of lipolysis in adipocytes
    K08044  ADCY4; adenylate cyclase 4
   04912 GnRH signaling pathway
    K08044  ADCY4; adenylate cyclase 4
   04913 Ovarian steroidogenesis
    K08044  ADCY4; adenylate cyclase 4
   04915 Estrogen signaling pathway
    K08044  ADCY4; adenylate cyclase 4
   04914 Progesterone-mediated oocyte maturation
    K08044  ADCY4; adenylate cyclase 4
   04921 Oxytocin signaling pathway
    K08044  ADCY4; adenylate cyclase 4
   04926 Relaxin signaling pathway
    K08044  ADCY4; adenylate cyclase 4
   04935 Growth hormone synthesis, secretion and action
    K08044  ADCY4; adenylate cyclase 4
   04918 Thyroid hormone synthesis
    K08044  ADCY4; adenylate cyclase 4
   04928 Parathyroid hormone synthesis, secretion and action
    K08044  ADCY4; adenylate cyclase 4
   04916 Melanogenesis
    K08044  ADCY4; adenylate cyclase 4
   04925 Aldosterone synthesis and secretion
    K08044  ADCY4; adenylate cyclase 4
   04927 Cortisol synthesis and secretion
    K08044  ADCY4; adenylate cyclase 4
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    K08044  ADCY4; adenylate cyclase 4
   04270 Vascular smooth muscle contraction
    K08044  ADCY4; adenylate cyclase 4
  09154 Digestive system
   04970 Salivary secretion
    K08044  ADCY4; adenylate cyclase 4
   04971 Gastric acid secretion
    K08044  ADCY4; adenylate cyclase 4
   04972 Pancreatic secretion
    K08044  ADCY4; adenylate cyclase 4
   04976 Bile secretion
    K08044  ADCY4; adenylate cyclase 4
  09156 Nervous system
   04724 Glutamatergic synapse
    K08044  ADCY4; adenylate cyclase 4
   04727 GABAergic synapse
    K08044  ADCY4; adenylate cyclase 4
   04725 Cholinergic synapse
    K08044  ADCY4; adenylate cyclase 4
   04723 Retrograde endocannabinoid signaling
    K08044  ADCY4; adenylate cyclase 4
  09157 Sensory system
   04742 Taste transduction
    K08044  ADCY4; adenylate cyclase 4
   04750 Inflammatory mediator regulation of TRP channels
    K08044  ADCY4; adenylate cyclase 4
  09149 Aging
   04211 Longevity regulating pathway
    K08044  ADCY4; adenylate cyclase 4
   04213 Longevity regulating pathway - multiple species
    K08044  ADCY4; adenylate cyclase 4
  09159 Environmental adaptation
   04713 Circadian entrainment
    K08044  ADCY4; adenylate cyclase 4
   04714 Thermogenesis
    K08044  ADCY4; adenylate cyclase 4
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K08044  ADCY4; adenylate cyclase 4
   05207 Chemical carcinogenesis - receptor activation
    K08044  ADCY4; adenylate cyclase 4
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K08044  ADCY4; adenylate cyclase 4
   05163 Human cytomegalovirus infection
    K08044  ADCY4; adenylate cyclase 4
  09165 Substance dependence
   05032 Morphine addiction
    K08044  ADCY4; adenylate cyclase 4
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    K08044  ADCY4; adenylate cyclase 4
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    K08044  ADCY4; adenylate cyclase 4
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    K08044  ADCY4; adenylate cyclase 4
Enzymes [BR:ko01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     K08044  ADCY4; adenylate cyclase 4
Other DBs
RN: R00089 R00434
GO: 0004016
Genes
HSA: 196883(ADCY4)
PTR: 452819(ADCY4)
PPS: 100978200(ADCY4)
GGO: 101125890(ADCY4)
PON: 100460806(ADCY4)
NLE: 100603282(ADCY4)
MCC: 714684(ADCY4)
MCF: 102123837(ADCY4)
CSAB: 103228726(ADCY4)
CATY: 105600225(ADCY4)
PANU: 101021139(ADCY4)
TGE: 112629482(ADCY4)
RRO: 104662674(ADCY4)
RBB: 108540946(ADCY4)
TFN: 117069900(ADCY4)
PTEH: 111552878(ADCY4)
CJC: 100415141(ADCY4)
SBQ: 101044688(ADCY4)
CSYR: 103272228(ADCY4)
MMUR: 105866617(ADCY4)
OGA: 100949638(ADCY4)
MMU: 104110(Adcy4)
MCAL: 110309267(Adcy4)
MPAH: 110325439(Adcy4)
RNO: 54223(Adcy4)
MCOC: 116084111(Adcy4)
MUN: 110556521(Adcy4)
CGE: 100768998(Adcy4)
PLEU: 114708701(Adcy4)
NGI: 103739411(Adcy4)
HGL: 101719464(Adcy4)
CPOC: 100715532(Adcy4)
CCAN: 109685852(Adcy4)
DORD: 105992475(Adcy4)
DSP: 122113375(Adcy4)
OCU: 100346742(ADCY4)
OPI: 101527552(ADCY4)
TUP: 102490273(ADCY4)
CFA: 480271(ADCY4)
VVP: 112926558(ADCY4)
VLG: 121493259(ADCY4)
AML: 100471940(ADCY4)
UMR: 103679331(ADCY4)
UAH: 113246056(ADCY4)
UAR: 123795737(ADCY4)
ELK: 111162403
LLV: 125104720
MPUF: 101676211(ADCY4)
ORO: 101374313(ADCY4)
EJU: 114217911(ADCY4)
ZCA: 113908984(ADCY4)
MLX: 118003693(ADCY4)
FCA: 101097735(ADCY4)
PYU: 121031569(ADCY4)
PBG: 122468944(ADCY4)
PTG: 102965866(ADCY4)
PPAD: 109254969(ADCY4)
AJU: 106987869(ADCY4)
HHV: 120247005(ADCY4)
BTA: 788151(ADCY4)
BOM: 102286168(ADCY4)
BIU: 109564199(ADCY4)
BBUB: 102408103(ADCY4)
CHX: 102185469(ADCY4)
OAS: 101119139(ADCY4)
ODA: 120853482(ADCY4)
CCAD: 122443147(ADCY4)
SSC: 100152067(ADCY4)
CFR: 102524031(ADCY4)
CBAI: 105068818(ADCY4)
CDK: 105102432(ADCY4)
VPC: 102544207(ADCY4)
BACU: 103005549(ADCY4)
LVE: 103075499(ADCY4)
OOR: 101289858(ADCY4)
DLE: 111164225(ADCY4)
PCAD: 102985820(ADCY4)
PSIU: 116749116(ADCY4)
ECB: 100054305(ADCY4)
EPZ: 103561050(ADCY4)
EAI: 106848607(ADCY4)
MYB: 102247996(ADCY4)
MYD: 102762536(ADCY4)
MMYO: 118678616(ADCY4)
MLF: 102417969(ADCY4)
MNA: 107531740(ADCY4)
PKL: 118725960(ADCY4)
HAI: 109393593(ADCY4)
DRO: 112300586(ADCY4)
SHON: 118980863(ADCY4)
AJM: 119037286(ADCY4)
PDIC: 114492860(ADCY4)
PHAS: 123820487(ADCY4)
MMF: 118631458(ADCY4)
RFQ: 117024169(ADCY4)
PALE: 102890575(ADCY4)
PGIG: 120608523(ADCY4)
PVP: 105309400(ADCY4)
RAY: 107498014(ADCY4)
MJV: 108410207(ADCY4)
TOD: 119238960(ADCY4)
SARA: 101539776(ADCY4)
LAV: 100675525(ADCY4)
TMU: 101350438
DNM: 101419332(ADCY4)
MDO: 100030872(ADCY4)
GAS: 123237960(ADCY4)
SHR: 100920243(ADCY4)
PCW: 110197384(ADCY4)
OAA: 103168714(ADCY4)
ASN: 102385636(ADCY4)
AMJ: 102558956(ADCY4)
PSS: 102451515
CMY: 102946725(ADCY4)
CPIC: 101936524(ADCY4)
TST: 117886223
CABI: 116839023(ADCY4)
MRV: 120380361(ADCY4)
ACS: 100562762(adcy4)
PVT: 110091692(ADCY4)
SUND: 121935289(ADCY4)
PBI: 103055695(ADCY4)
PMUR: 107286594(ADCY4)
TSR: 106549385(ADCY4)
PGUT: 117662171(ADCY4)
VKO: 123021770(ADCY4)
PMUA: 114581737(ADCY4)
ZVI: 118078718(ADCY4)
GJA: 107111738(ADCY4)
XLA: 108707036 108715027(adcy4.L)
XTR: 100497212(adcy4)
NPR: 108788450(ADCY4)
RTEM: 120940456(ADCY4)
BBUF: 120988965(ADCY4)
BGAR: 122923965(ADCY4)
SRX: 107720483 107740771
SANH: 107693500 107698135
SGH: 107572836
CCAR: 109102764
CAUA: 113096274 113105408
IPU: 108260803
PHYP: 113544317
AMEX: 103031621
EEE: 113591496
KMR: 108248619
ALIM: 106527078
CSEM: 103384541
LCF: 108890756
HCQ: 109516520
BPEC: 110158296
SASA: 106608969
OTW: 112215078
OMY: 110500394
ONE: 115131798
SALP: 111952465
ELS: 105030097
PKI: 111856451
PSPA: 121305249 121307360
ARUT: 117398126 117398838
BANY: 112043014
OVI: T265_02367
 » show all
Reference
PMID:12503609
  Authors
Ludwig MG, Seuwen K
  Title
Characterization of the human adenylyl cyclase gene family: cDNA, gene structure, and tissue distribution of the nine isoforms.
  Journal
J Recept Signal Transduct Res 22:79-110 (2002)
DOI:10.1081/RRS-120014589
  Sequence
[hsa:196883]
LinkDB

KEGG   ORTHOLOGY: K08047
Entry
K08047                      KO                                     
Symbol
ADCY7
Name
adenylate cyclase 7 [EC:4.6.1.1]
Pathway
map00230  Purine metabolism
map01100  Metabolic pathways
map01522  Endocrine resistance
map04015  Rap1 signaling pathway
map04020  Calcium signaling pathway
map04022  cGMP-PKG signaling pathway
map04024  cAMP signaling pathway
map04062  Chemokine signaling pathway
map04072  Phospholipase D signaling pathway
map04114  Oocyte meiosis
map04211  Longevity regulating pathway
map04213  Longevity regulating pathway - multiple species
map04261  Adrenergic signaling in cardiomyocytes
map04270  Vascular smooth muscle contraction
map04371  Apelin signaling pathway
map04540  Gap junction
map04611  Platelet activation
map04713  Circadian entrainment
map04714  Thermogenesis
map04723  Retrograde endocannabinoid signaling
map04724  Glutamatergic synapse
map04725  Cholinergic synapse
map04727  GABAergic synapse
map04750  Inflammatory mediator regulation of TRP channels
map04911  Insulin secretion
map04912  GnRH signaling pathway
map04913  Ovarian steroidogenesis
map04914  Progesterone-mediated oocyte maturation
map04915  Estrogen signaling pathway
map04916  Melanogenesis
map04918  Thyroid hormone synthesis
map04921  Oxytocin signaling pathway
map04923  Regulation of lipolysis in adipocytes
map04925  Aldosterone synthesis and secretion
map04926  Relaxin signaling pathway
map04927  Cortisol synthesis and secretion
map04928  Parathyroid hormone synthesis, secretion and action
map04934  Cushing syndrome
map04935  Growth hormone synthesis, secretion and action
map04970  Salivary secretion
map04971  Gastric acid secretion
map04972  Pancreatic secretion
map04976  Bile secretion
map05032  Morphine addiction
map05163  Human cytomegalovirus infection
map05166  Human T-cell leukemia virus 1 infection
map05200  Pathways in cancer
map05207  Chemical carcinogenesis - receptor activation
map05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    K08047  ADCY7; adenylate cyclase 7
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    K08047  ADCY7; adenylate cyclase 7
   04371 Apelin signaling pathway
    K08047  ADCY7; adenylate cyclase 7
   04020 Calcium signaling pathway
    K08047  ADCY7; adenylate cyclase 7
   04072 Phospholipase D signaling pathway
    K08047  ADCY7; adenylate cyclase 7
   04024 cAMP signaling pathway
    K08047  ADCY7; adenylate cyclase 7
   04022 cGMP-PKG signaling pathway
    K08047  ADCY7; adenylate cyclase 7
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    K08047  ADCY7; adenylate cyclase 7
  09144 Cellular community - eukaryotes
   04540 Gap junction
    K08047  ADCY7; adenylate cyclase 7
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    K08047  ADCY7; adenylate cyclase 7
   04062 Chemokine signaling pathway
    K08047  ADCY7; adenylate cyclase 7
  09152 Endocrine system
   04911 Insulin secretion
    K08047  ADCY7; adenylate cyclase 7
   04923 Regulation of lipolysis in adipocytes
    K08047  ADCY7; adenylate cyclase 7
   04912 GnRH signaling pathway
    K08047  ADCY7; adenylate cyclase 7
   04913 Ovarian steroidogenesis
    K08047  ADCY7; adenylate cyclase 7
   04915 Estrogen signaling pathway
    K08047  ADCY7; adenylate cyclase 7
   04914 Progesterone-mediated oocyte maturation
    K08047  ADCY7; adenylate cyclase 7
   04921 Oxytocin signaling pathway
    K08047  ADCY7; adenylate cyclase 7
   04926 Relaxin signaling pathway
    K08047  ADCY7; adenylate cyclase 7
   04935 Growth hormone synthesis, secretion and action
    K08047  ADCY7; adenylate cyclase 7
   04918 Thyroid hormone synthesis
    K08047  ADCY7; adenylate cyclase 7
   04928 Parathyroid hormone synthesis, secretion and action
    K08047  ADCY7; adenylate cyclase 7
   04916 Melanogenesis
    K08047  ADCY7; adenylate cyclase 7
   04925 Aldosterone synthesis and secretion
    K08047  ADCY7; adenylate cyclase 7
   04927 Cortisol synthesis and secretion
    K08047  ADCY7; adenylate cyclase 7
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    K08047  ADCY7; adenylate cyclase 7
   04270 Vascular smooth muscle contraction
    K08047  ADCY7; adenylate cyclase 7
  09154 Digestive system
   04970 Salivary secretion
    K08047  ADCY7; adenylate cyclase 7
   04971 Gastric acid secretion
    K08047  ADCY7; adenylate cyclase 7
   04972 Pancreatic secretion
    K08047  ADCY7; adenylate cyclase 7
   04976 Bile secretion
    K08047  ADCY7; adenylate cyclase 7
  09156 Nervous system
   04724 Glutamatergic synapse
    K08047  ADCY7; adenylate cyclase 7
   04727 GABAergic synapse
    K08047  ADCY7; adenylate cyclase 7
   04725 Cholinergic synapse
    K08047  ADCY7; adenylate cyclase 7
   04723 Retrograde endocannabinoid signaling
    K08047  ADCY7; adenylate cyclase 7
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    K08047  ADCY7; adenylate cyclase 7
  09149 Aging
   04211 Longevity regulating pathway
    K08047  ADCY7; adenylate cyclase 7
   04213 Longevity regulating pathway - multiple species
    K08047  ADCY7; adenylate cyclase 7
  09159 Environmental adaptation
   04713 Circadian entrainment
    K08047  ADCY7; adenylate cyclase 7
   04714 Thermogenesis
    K08047  ADCY7; adenylate cyclase 7
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K08047  ADCY7; adenylate cyclase 7
   05207 Chemical carcinogenesis - receptor activation
    K08047  ADCY7; adenylate cyclase 7
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K08047  ADCY7; adenylate cyclase 7
   05163 Human cytomegalovirus infection
    K08047  ADCY7; adenylate cyclase 7
  09165 Substance dependence
   05032 Morphine addiction
    K08047  ADCY7; adenylate cyclase 7
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    K08047  ADCY7; adenylate cyclase 7
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    K08047  ADCY7; adenylate cyclase 7
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    K08047  ADCY7; adenylate cyclase 7
Enzymes [BR:ko01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     K08047  ADCY7; adenylate cyclase 7
Other DBs
RN: R00089 R00434
GO: 0004016
Genes
HSA: 113(ADCY7)
PTR: 473278(ADCY7)
PPS: 100984225(ADCY7)
GGO: 101126268(ADCY7)
PON: 100436577(ADCY7)
NLE: 100587036(ADCY7)
MCC: 694730(ADCY7)
MCF: 102125718(ADCY7)
CSAB: 103232667(ADCY7)
CATY: 105588901(ADCY7)
PANU: 101000833(ADCY7)
TGE: 112613998(ADCY7)
RRO: 104672569(ADCY7)
RBB: 108522948(ADCY7)
TFN: 117087765(ADCY7)
PTEH: 111541238(ADCY7)
CJC: 100404620(ADCY7)
SBQ: 101032672(ADCY7)
CSYR: 103259338(ADCY7)
MMUR: 105884745(ADCY7)
OGA: 100956925(ADCY7)
MMU: 11513(Adcy7)
MCAL: 110299719(Adcy7)
MPAH: 110337453(Adcy7)
RNO: 84420(Adcy7)
MCOC: 116069817(Adcy7)
MUN: 110560723(Adcy7)
CGE: 100756132(Adcy7)
PLEU: 114708501(Adcy7)
NGI: 103730120(Adcy7)
HGL: 101712483(Adcy7)
CPOC: 100726699(Adcy7)
CCAN: 109698373(Adcy7)
DORD: 105994440(Adcy7)
DSP: 122119361(Adcy7)
OCU: 100357357(ADCY7)
OPI: 101519430(ADCY7)
TUP: 102496578(ADCY7)
CFA: 487289(ADCY7)
VVP: 112929565(ADCY7)
VLG: 121497930(ADCY7)
AML: 100466965(ADCY7)
UMR: 103673916(ADCY7)
UAH: 113252223(ADCY7)
UAR: 123798393(ADCY7)
ELK: 111157326
LLV: 125088705
MPUF: 101684190(ADCY7)
ORO: 101377421(ADCY7)
EJU: 114202960 114202963
ZCA: 113935770(ADCY7)
MLX: 118023800(ADCY7)
FCA: 101094148(ADCY7)
PYU: 121045271(ADCY7)
PBG: 122494184(ADCY7)
PTG: 102972917(ADCY7)
PPAD: 109270953(ADCY7)
AJU: 106985835(ADCY7)
HHV: 120238226(ADCY7)
BTA: 281603(ADCY7)
BOM: 102266966(ADCY7)
BIU: 109572478(ADCY7)
BBUB: 102410456(ADCY7)
CHX: 102185858(ADCY7)
OAS: 101112667(ADCY7)
ODA: 120872811(ADCY7)
CCAD: 122421548(ADCY7)
SSC: 100620994(ADCY7)
CFR: 102524614(ADCY7)
CBAI: 105074271(ADCY7)
CDK: 105097528(ADCY7)
VPC: 102529498(ADCY7)
BACU: 102997912(ADCY7)
LVE: 103078677(ADCY7)
OOR: 101273592(ADCY7)
DLE: 111164991(ADCY7)
PCAD: 102985075(ADCY7)
PSIU: 116744731(ADCY7)
ECB: 100058891(ADCY7)
EPZ: 103556685(ADCY7)
EAI: 106824126(ADCY7)
MYB: 102253549(ADCY7)
MYD: 102764043(ADCY7)
MMYO: 118674005(ADCY7)
MNA: 107531029(ADCY7)
PKL: 118720641(ADCY7)
HAI: 109383261(ADCY7)
DRO: 112296774(ADCY7)
SHON: 119001137(ADCY7)
AJM: 119046468(ADCY7)
PDIC: 114488191(ADCY7)
PHAS: 123805699(ADCY7)
MMF: 118639510(ADCY7)
RFQ: 117034378(ADCY7)
PALE: 102881535(ADCY7)
PGIG: 120617254(ADCY7)
PVP: 105292087(ADCY7)
RAY: 107512248(ADCY7)
MJV: 108407296(ADCY7)
TOD: 119249160(ADCY7)
SARA: 101543858(ADCY7)
LAV: 100653771(ADCY7)
TMU: 101341715
DNM: 101427927(ADCY7)
MDO: 100013823(ADCY7)
GAS: 123233664(ADCY7)
SHR: 100929278(ADCY7)
PCW: 110207473(ADCY7)
OAA: 100076221(ADCY7)
GGA: 415732(ADCY7)
PCOC: 116243930(ADCY7)
MGP: 100548914
CJO: 107319017(ADCY7)
NMEL: 110404374(ADCY7)
APLA: 101794076(ADCY7)
ACYG: 106039584(ADCY7)
AFUL: 116494191(ADCY7)
TGU: 100225700(ADCY7)
LSR: 110473537(ADCY7)
SCAN: 103816806(ADCY7)
PMOA: 120507978(ADCY7)
OTC: 121333986(ADCY7)
PRUF: 121348916(ADCY7)
GFR: 102043194(ADCY7)
FAB: 101816007(ADCY7)
PHI: 102106688(ADCY7)
PMAJ: 107209841(ADCY7)
CCAE: 111934618(ADCY7)
CCW: 104687454(ADCY7)
ETL: 114055552(ADCY7)
ZAB: 102073757(ADCY7)
FPG: 101914615(ADCY7)
FCH: 102052224(ADCY7)
CLV: 102090470(ADCY7)
EGZ: 104125176(ADCY7)
NNI: 104011289(ADCY7)
ACUN: 113484440(ADCY7)
TALA: 104368104(ADCY7)
PADL: 103913801(ADCY7)
ACHC: 115345521(ADCY7)
AAM: 106483289(ADCY7)
AROW: 112967538(ADCY7)
NPD: 112944957(ADCY7)
DNE: 112984414(ADCY7)
ASN: 102368976(ADCY7)
AMJ: 102566330(ADCY7)
CPOO: 109310532(ADCY7)
GGN: 109289593(ADCY7)
PSS: 102449192(ADCY7)
CMY: 102946407(ADCY7)
CPIC: 101938536(ADCY7)
TST: 117886819(ADCY7)
CABI: 116826976(ADCY7)
MRV: 120384768(ADCY7)
ACS: 100558751(adcy7)
PVT: 110086573(ADCY7)
SUND: 121914489(ADCY7)
PBI: 103060035(ADCY7)
PMUR: 107290046(ADCY7)
TSR: 106554339(ADCY7)
PGUT: 117670935(ADCY7)
VKO: 123022135(ADCY7)
PMUA: 114602227(ADCY7)
ZVI: 118085993(ADCY7)
GJA: 107117185(ADCY7)
XLA: 399055(adcy7.L)
XTR: 100127741(adcy7)
NPR: 108794932(ADCY7)
RTEM: 120917430(ADCY7)
BBUF: 120981193(ADCY7)
BGAR: 122920478(ADCY7)
DRE: 568726(adcy7)
SRX: 107742778 107750233
SANH: 107657123 107696709
SGH: 107551487 107554606
CCAR: 109080760 109091999
CAUA: 113051418 113106060
IPU: 108259218(adcy7)
PHYP: 113540899(adcy7)
SMEO: 124379641(adcy7)
AMEX: 103025161(adcy7)
EEE: 113581231
TRU: 101066272(adcy7)
LCO: 104940647(adcy7)
CGOB: 115005259(adcy7)
ELY: 117253092(adcy7)
PLEP: 121939187(adcy7)
SLUC: 116037616(adcy7)
ECRA: 117949494(adcy7)
PFLV: 114555545(adcy7)
GAT: 120811617(adcy7)
PPUG: 119226484(adcy7)
MSAM: 119889811(adcy7)
CUD: 121509307(adcy7)
MZE: 101480238(adcy7)
ONL: 100703488(adcy7)
OAU: 116325574(adcy7)
OLA: 101164967(adcy7)
OML: 112160437(adcy7)
XMA: 102223009(adcy7)
XCO: 114142861(adcy7)
XHE: 116718405(adcy7)
PRET: 103462645(adcy7)
PFOR: 103138067(adcy7)
PLAI: 106957719
PMEI: 106927339
GAF: 122825208(adcy7)
CVG: 107088499(adcy7)
CTUL: 119781951(adcy7)
GMU: 124867163(adcy7)
NFU: 107381237(adcy7)
KMR: 108243337(adcy7)
ALIM: 106527041
NWH: 119426404(adcy7)
AOCE: 111572244(adcy7)
CSEM: 103398552
POV: 109625125(adcy7)
SSEN: 122772187(adcy7)
HHIP: 117759592(adcy7)
LCF: 108876970(adcy7)
SDU: 111217971(adcy7)
SLAL: 111672304(adcy7)
XGL: 120789257(adcy7)
HCQ: 109513976(adcy7)
BPEC: 110175272(adcy7)
MALB: 109955816(adcy7)
SASA: 106562384 106587576
OTW: 112249333 112249354
OMY: 110506731 110526596
OGO: 124033586 124035566
ONE: 115112487 115113769
SALP: 111974474
SNH: 120024860 120048037
ELS: 105025700(adcy7)
SFM: 108932972
PKI: 111832687 111848207
AANG: 118215074(adcy7) 118227441
LOC: 102689559(adcy7)
PSPA: 121296167 121325516
ARUT: 117424464(adcy7) 117425878
LCM: 102351065(ADCY7)
CMK: 103176081(adcy7)
RTP: 109923754
DMK: 116929418
DFR: 124491502
 » show all
Reference
PMID:7961850
  Authors
Watson PA, Krupinski J, Kempinski AM, Frankenfield CD
  Title
Molecular cloning and characterization of the type VII isoform of mammalian adenylyl cyclase expressed widely in mouse tissues and in S49 mouse lymphoma cells.
  Journal
J Biol Chem 269:28893-8 (1994)
  Sequence
[hsa:113]
Reference
PMID:22264442
  Authors
Joeyen-Waldorf J, Nikolova YS, Edgar N, Walsh C, Kota R, Lewis DA, Ferrell R, Manuck SB, Hariri AR, Sibille E
  Title
Adenylate cyclase 7 is implicated in the biology of depression and modulation of affective neural circuitry.
  Journal
Biol Psychiatry 71:627-32 (2012)
DOI:10.1016/j.biopsych.2011.11.029
LinkDB

KEGG   ORTHOLOGY: K08048
Entry
K08048                      KO                                     
Symbol
ADCY8
Name
adenylate cyclase 8 [EC:4.6.1.1]
Pathway
map00230  Purine metabolism
map01100  Metabolic pathways
map01522  Endocrine resistance
map04015  Rap1 signaling pathway
map04020  Calcium signaling pathway
map04022  cGMP-PKG signaling pathway
map04024  cAMP signaling pathway
map04062  Chemokine signaling pathway
map04072  Phospholipase D signaling pathway
map04114  Oocyte meiosis
map04211  Longevity regulating pathway
map04213  Longevity regulating pathway - multiple species
map04261  Adrenergic signaling in cardiomyocytes
map04270  Vascular smooth muscle contraction
map04371  Apelin signaling pathway
map04540  Gap junction
map04611  Platelet activation
map04713  Circadian entrainment
map04714  Thermogenesis
map04720  Long-term potentiation
map04723  Retrograde endocannabinoid signaling
map04724  Glutamatergic synapse
map04725  Cholinergic synapse
map04727  GABAergic synapse
map04742  Taste transduction
map04750  Inflammatory mediator regulation of TRP channels
map04911  Insulin secretion
map04912  GnRH signaling pathway
map04913  Ovarian steroidogenesis
map04914  Progesterone-mediated oocyte maturation
map04915  Estrogen signaling pathway
map04916  Melanogenesis
map04918  Thyroid hormone synthesis
map04921  Oxytocin signaling pathway
map04923  Regulation of lipolysis in adipocytes
map04925  Aldosterone synthesis and secretion
map04926  Relaxin signaling pathway
map04927  Cortisol synthesis and secretion
map04928  Parathyroid hormone synthesis, secretion and action
map04934  Cushing syndrome
map04935  Growth hormone synthesis, secretion and action
map04970  Salivary secretion
map04971  Gastric acid secretion
map04972  Pancreatic secretion
map04976  Bile secretion
map05032  Morphine addiction
map05163  Human cytomegalovirus infection
map05166  Human T-cell leukemia virus 1 infection
map05200  Pathways in cancer
map05207  Chemical carcinogenesis - receptor activation
map05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    K08048  ADCY8; adenylate cyclase 8
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    K08048  ADCY8; adenylate cyclase 8
   04371 Apelin signaling pathway
    K08048  ADCY8; adenylate cyclase 8
   04020 Calcium signaling pathway
    K08048  ADCY8; adenylate cyclase 8
   04072 Phospholipase D signaling pathway
    K08048  ADCY8; adenylate cyclase 8
   04024 cAMP signaling pathway
    K08048  ADCY8; adenylate cyclase 8
   04022 cGMP-PKG signaling pathway
    K08048  ADCY8; adenylate cyclase 8
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    K08048  ADCY8; adenylate cyclase 8
  09144 Cellular community - eukaryotes
   04540 Gap junction
    K08048  ADCY8; adenylate cyclase 8
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    K08048  ADCY8; adenylate cyclase 8
   04062 Chemokine signaling pathway
    K08048  ADCY8; adenylate cyclase 8
  09152 Endocrine system
   04911 Insulin secretion
    K08048  ADCY8; adenylate cyclase 8
   04923 Regulation of lipolysis in adipocytes
    K08048  ADCY8; adenylate cyclase 8
   04912 GnRH signaling pathway
    K08048  ADCY8; adenylate cyclase 8
   04913 Ovarian steroidogenesis
    K08048  ADCY8; adenylate cyclase 8
   04915 Estrogen signaling pathway
    K08048  ADCY8; adenylate cyclase 8
   04914 Progesterone-mediated oocyte maturation
    K08048  ADCY8; adenylate cyclase 8
   04921 Oxytocin signaling pathway
    K08048  ADCY8; adenylate cyclase 8
   04926 Relaxin signaling pathway
    K08048  ADCY8; adenylate cyclase 8
   04935 Growth hormone synthesis, secretion and action
    K08048  ADCY8; adenylate cyclase 8
   04918 Thyroid hormone synthesis
    K08048  ADCY8; adenylate cyclase 8
   04928 Parathyroid hormone synthesis, secretion and action
    K08048  ADCY8; adenylate cyclase 8
   04916 Melanogenesis
    K08048  ADCY8; adenylate cyclase 8
   04925 Aldosterone synthesis and secretion
    K08048  ADCY8; adenylate cyclase 8
   04927 Cortisol synthesis and secretion
    K08048  ADCY8; adenylate cyclase 8
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    K08048  ADCY8; adenylate cyclase 8
   04270 Vascular smooth muscle contraction
    K08048  ADCY8; adenylate cyclase 8
  09154 Digestive system
   04970 Salivary secretion
    K08048  ADCY8; adenylate cyclase 8
   04971 Gastric acid secretion
    K08048  ADCY8; adenylate cyclase 8
   04972 Pancreatic secretion
    K08048  ADCY8; adenylate cyclase 8
   04976 Bile secretion
    K08048  ADCY8; adenylate cyclase 8
  09156 Nervous system
   04724 Glutamatergic synapse
    K08048  ADCY8; adenylate cyclase 8
   04727 GABAergic synapse
    K08048  ADCY8; adenylate cyclase 8
   04725 Cholinergic synapse
    K08048  ADCY8; adenylate cyclase 8
   04720 Long-term potentiation
    K08048  ADCY8; adenylate cyclase 8
   04723 Retrograde endocannabinoid signaling
    K08048  ADCY8; adenylate cyclase 8
  09157 Sensory system
   04742 Taste transduction
    K08048  ADCY8; adenylate cyclase 8
   04750 Inflammatory mediator regulation of TRP channels
    K08048  ADCY8; adenylate cyclase 8
  09149 Aging
   04211 Longevity regulating pathway
    K08048  ADCY8; adenylate cyclase 8
   04213 Longevity regulating pathway - multiple species
    K08048  ADCY8; adenylate cyclase 8
  09159 Environmental adaptation
   04713 Circadian entrainment
    K08048  ADCY8; adenylate cyclase 8
   04714 Thermogenesis
    K08048  ADCY8; adenylate cyclase 8
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K08048  ADCY8; adenylate cyclase 8
   05207 Chemical carcinogenesis - receptor activation
    K08048  ADCY8; adenylate cyclase 8
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K08048  ADCY8; adenylate cyclase 8
   05163 Human cytomegalovirus infection
    K08048  ADCY8; adenylate cyclase 8
  09165 Substance dependence
   05032 Morphine addiction
    K08048  ADCY8; adenylate cyclase 8
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    K08048  ADCY8; adenylate cyclase 8
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    K08048  ADCY8; adenylate cyclase 8
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    K08048  ADCY8; adenylate cyclase 8
Enzymes [BR:ko01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     K08048  ADCY8; adenylate cyclase 8
Other DBs
RN: R00089 R00434
GO: 0008294
Genes
HSA: 114(ADCY8)
PTR: 464400(ADCY8)
PPS: 100994715(ADCY8)
GGO: 101142672(ADCY8)
PON: 100461383(ADCY8)
NLE: 100592592(ADCY8)
MCC: 695792(ADCY8)
MCF: 102144854(ADCY8)
CSAB: 103237447(ADCY8)
CATY: 105588369(ADCY8)
PANU: 101007115(ADCY8)
TGE: 112630332(ADCY8)
RRO: 104675683(ADCY8)
RBB: 108514094(ADCY8)
TFN: 117079299(ADCY8)
PTEH: 111549769(ADCY8)
CJC: 100404484(ADCY8)
SBQ: 101034552(ADCY8)
CSYR: 103267869(ADCY8)
MMUR: 105882731(ADCY8)
OGA: 100952034(ADCY8)
MMU: 11514(Adcy8)
MCAL: 110310371(Adcy8)
MPAH: 110334612(Adcy8)
RNO: 29241(Adcy8)
MCOC: 116082049(Adcy8)
CGE: 113837458
PLEU: 114697724(Adcy8)
NGI: 103743923(Adcy8)
HGL: 101698293(Adcy8)
CPOC: 100722340(Adcy8)
CCAN: 109678665(Adcy8)
DORD: 105992323(Adcy8)
DSP: 122125337(Adcy8)
OCU: 100337882(ADCY8)
OPI: 101523667(ADCY8)
TUP: 102472317(ADCY8)
CFA: 482045(ADCY8)
VVP: 112915982(ADCY8)
VLG: 121498514(ADCY8)
AML: 100474121(ADCY8)
UMR: 103661704(ADCY8)
UAH: 113252717(ADCY8)
UAR: 123801897(ADCY8)
ELK: 111146667
LLV: 125098951
MPUF: 101693988(ADCY8)
ORO: 101370350(ADCY8)
EJU: 114211178(ADCY8)
ZCA: 113934371(ADCY8)
MLX: 118015219(ADCY8)
FCA: 101087555(ADCY8)
PYU: 121042990(ADCY8)
PBG: 122495819(ADCY8)
PTG: 102948581(ADCY8)
PPAD: 109273118(ADCY8)
AJU: 106976879(ADCY8)
HHV: 120221853(ADCY8)
BTA: 535017(ADCY8)
BOM: 102272964(ADCY8)
BIU: 109568647(ADCY8)
BBUB: 102395302(ADCY8)
CHX: 102184919(ADCY8)
OAS: 101121944(ADCY8)
ODA: 120878868(ADCY8)
CCAD: 122451315(ADCY8)
SSC: 100622999(ADCY8)
CFR: 102521259(ADCY8)
CBAI: 105082946(ADCY8)
CDK: 105096450(ADCY8)
VPC: 102543885(ADCY8)
BACU: 103019172(ADCY8)
LVE: 103085845(ADCY8)
OOR: 101273171(ADCY8)
DLE: 111164400(ADCY8)
PCAD: 102975211(ADCY8)
PSIU: 116742406(ADCY8)
ECB: 100057796(ADCY8)
EPZ: 103565019 103567623(ADCY8)
EAI: 106824833(ADCY8)
MYB: 102249345(ADCY8)
MYD: 102765722(ADCY8)
MMYO: 118670715(ADCY8)
MLF: 102423495(ADCY8)
MNA: 107539500(ADCY8)
PKL: 118718663(ADCY8)
HAI: 109372359(ADCY8)
DRO: 112315487(ADCY8)
SHON: 118988683(ADCY8)
AJM: 119064806(ADCY8)
PDIC: 114514654(ADCY8)
PHAS: 123833093(ADCY8)
MMF: 118631528(ADCY8)
RFQ: 117033942(ADCY8)
PALE: 102896789(ADCY8)
PGIG: 120588721(ADCY8)
PVP: 105301250(ADCY8)
RAY: 107497689(ADCY8)
MJV: 108397669(ADCY8)
TOD: 119237825(ADCY8)
SARA: 101550559(ADCY8)
LAV: 100661616(ADCY8)
TMU: 101350704
DNM: 101422732
MDO: 100026554(ADCY8)
GAS: 123241596(ADCY8)
SHR: 100923926(ADCY8)
PCW: 110216073(ADCY8)
OAA: 100077908(ADCY8)
GGA: 420328(ADCY8)
PCOC: 116227752(ADCY8)
MGP: 100548951(ADCY8)
CJO: 107310566(ADCY8)
NMEL: 110394336(ADCY8)
APLA: 101794043(ADCY8)
ACYG: 106046364(ADCY8)
AFUL: 116486321(ADCY8)
TGU: 100230277(ADCY8)
LSR: 110476995(ADCY8)
SCAN: 103816719(ADCY8)
PMOA: 120505202(ADCY8)
OTC: 121337449(ADCY8)
PRUF: 121364662(ADCY8)
GFR: 102037430(ADCY8)
FAB: 101809046(ADCY8)
PHI: 102108193(ADCY8)
PMAJ: 107200813(ADCY8)
CCAE: 111925137 111925138
CCW: 104692638(ADCY8)
ETL: 114065892(ADCY8)
ZAB: 102061077(ADCY8)
FPG: 101921528(ADCY8)
FCH: 102056487(ADCY8)
CLV: 102086133(ADCY8)
EGZ: 104134444(ADCY8)
NNI: 104016868(ADCY8)
ACUN: 113476386(ADCY8)
TALA: 104358260(ADCY8)
PADL: 103916382(ADCY8)
ACHC: 115340454(ADCY8)
AAM: 106496221(ADCY8)
AROW: 112971840(ADCY8)
NPD: 112959414(ADCY8)
DNE: 112991309(ADCY8)
ASN: 102369910(ADCY8)
AMJ: 102562540(ADCY8)
CPOO: 109322048(ADCY8)
GGN: 109305202(ADCY8)
PSS: 102448969(ADCY8)
CMY: 102930804(ADCY8)
CPIC: 101947738(ADCY8)
TST: 117873819(ADCY8)
CABI: 116823168(ADCY8)
MRV: 120399258(ADCY8)
ACS: 100556578(adcy8)
PVT: 110090751(ADCY8)
SUND: 121929803(ADCY8)
PBI: 103049018(ADCY8)
PMUR: 107289979(ADCY8)
TSR: 106542281
PGUT: 117668453(ADCY8)
VKO: 123033688(ADCY8)
PMUA: 114600245(ADCY8)
ZVI: 118089989(ADCY8)
GJA: 107119214(ADCY8)
XLA: 108719413(adcy8.L) 414729(adcy8.S)
XTR: 549366
NPR: 108788952(ADCY8)
RTEM: 120941534(ADCY8)
BBUF: 121001129(ADCY8)
DRE: 100148976(adcy8) 560410(si:ch211-132f19.7) 560719(si:dkey-206f10.1)
SRX: 107721761 107726739 107733159 107743294 107749169
SANH: 107659784 107663336 107674102 107697672
SGH: 107549698 107557810 107569488 107592799 107594777 107603098
CCAR: 109049343 109053960 109078891 109108520(adcy8)
CAUA: 113045049 113060337 113092585 113120779 113120872
IPU: 108257757(si:dkey-206f10.1) 108280230(adcy8)
PHYP: 113532110 113543309(adcy8)
SMEO: 124376502(si:dkey-206f10.1) 124403016(adcy8)
AMEX: 103023616 103024991(adcy8) 103031589
EEE: 113584128(adcy8)
TRU: 101073369 101073390 101076392(adcy8)
TNG: GSTEN00012568G001 GSTEN00015280G001 GSTEN00030377G001
LCO: 104922014 104938356(adcy8)
NCC: 104955036(adcy8)
CGOB: 115022284(adcy8) 115028833
ELY: 117250016 117270489(si:dkey-206f10.1) 117272061(adcy8)
PLEP: 121951261(adcy8) 121955835(si:dkey-206f10.1)
SLUC: 116044740(adcy8) 116066255(si:dkey-206f10.1)
ECRA: 117953964(adcy8) 117961123(si:dkey-206f10.1)
PFLV: 114564992(adcy8) 114572973
GAT: 120808486
PPUG: 119194976(si:dkey-206f10.1) 119209002(adcy8)
MSAM: 119901661(adcy8) 119908444 119908457(si:dkey-206f10.1) 119915897
CUD: 121506508 121519638(adcy8) 121521629(si:dkey-206f10.1)
MZE: 101465620(adcy8) 101468839 101473876
ONL: 100705805 100706035 100708106(adcy8)
OAU: 116310796(si:dkey-206f10.1) 116316516(adcy8) 116325033
OLA: 101161086(adcy8) 101162414 101162988
OML: 112144246(adcy8) 112156739 112158536(si:dkey-206f10.1)
XMA: 102218852(adcy8) 102231024 102236399
XCO: 114140665 114146247(adcy8) 114158148
XHE: 116715629 116720923(adcy8) 116734023
PRET: 103457562 103480038(adcy8) 103481184
PFOR: 103138590 103150940 103156017(adcy8)
PLAI: 106949201 106950379 106955875
PMEI: 106905188 106910104 106928777(adcy8)
GAF: 122825293(si:dkey-206f10.1) 122826983(si:ch211-132f19.7) 122841663(adcy8)
CVG: 107083338 107086997(adcy8) 107104317
CTUL: 119784215(adcy8) 119785063(si:dkey-206f10.1) 119791543
GMU: 124861404 124870367(adcy8) 124881823(si:dkey-206f10.1)
NFU: 107377600 107383681(adcy8) 107384598
KMR: 108229092(si:ch211-132f19.7) 108246168(adcy8)
ALIM: 106527219(adcy8) 106531266
NWH: 119415271(adcy8) 119428743(si:ch211-132f19.7)
AOCE: 111566062 111568870(adcy8) 111584658
CSEM: 103380838 103396830(adcy8)
POV: 109636103 109646927
SSEN: 122762475(adcy8) 122783786(si:dkey-206f10.1)
HHIP: 117758266(si:dkey-206f10.1) 117778572(adcy8) 117778677
LCF: 108877174 108882439(adcy8) 108895615
SDU: 111233908(adcy8) 111235549 111236701
SLAL: 111646845 111647103(adcy8) 111650568
XGL: 120788729(si:dkey-206f10.1) 120798356 120799361(adcy8)
HCQ: 109518125 109518881(adcy8)
BPEC: 110155800 110165875(adcy8)
MALB: 109970259(adcy8) 109971087
SASA: 106568630(adcy8) 106611404
OTW: 112250071(adcy8) 112255820(si:ch211-132f19.7)
OMY: 110504263(si:ch211-132f19.7) 110529931(adcy8)
OGO: 124009784(adcy8) 124045363(si:ch211-132f19.7)
ONE: 115114051(adcy8) 115123485
SALP: 111957123(adcy8) 112076728
SNH: 120022998(si:ch211-132f19.7) 120056232(adcy8)
ELS: 105023619(adcy8) 105031560
SFM: 108918520 108937764(adcy8)
PKI: 111845896(adcy8)
AANG: 118229366(si:dkey-206f10.1) 118234492(adcy8)
LOC: 102685748(adcy8) 102694194
PSPA: 121309014(adcy8)
ARUT: 117399547(adcy8)
LCM: 102346737(ADCY8)
CMK: 103183440(adcy8)
RTP: 109914598(adcy8)
BFO: 118405038
BBEL: 109476272
CIN: 100181005
SCLV: 120336024
SKO: 100370378
DME: Dmel_CG10564(Ac78C)
DER: 6546178
DSE: 6616399
DSI: Dsimw501_GD12142(Dsim_GD12142)
DYA: Dyak_GE22718
DAN: 6493061
DSR: 110189946
DPO: Dpse_GA10398
DPE: 6602992
DMN: 108152936
DWI: 6645098
DGR: 6558351
DMO: Dmoj_GI13820
DNV: 108652084
DHE: 111599815
DVI: 6623758
CCAT: 101449938
BOD: 106622843
MDE: 101893364
SCAC: 106093569 106094892
LCQ: 111677112
AGA: AgaP_AGAP002262
ACOZ: 120949475
AARA: 120894424
AAG: 5563558
AALB: 109414810
CQU: CpipJ_CPIJ015189
CPII: 120415895
CNS: 116342455
AME: 726262
ACER: 107993030
ALAB: 122714062
BIM: 100741339
BBIF: 117209501
BVK: 117233726
BVAN: 117158627
BTER: 100650732
BPYO: 122571917
CCAL: 108626074
OBB: 114874916
MGEN: 117228046
NMEA: 116426288
CGIG: 122401165
SOC: 105208160
MPHA: 105831878
AEC: 105145442
ACEP: 105621896
PBAR: 105425253
VEM: 105566125
HST: 105185447
DQU: 106740959
CFO: 105247922
FEX: 115242516
LHU: 105672367
PGC: 109856473
OBO: 105279868
PCF: 106787929
PFUC: 122513875
VPS: 122633833
NVI: 100679362
CSOL: 105367908
TPRE: 106651649
MDL: 103569316
CGLO: 123261994
FAS: 105267081
DAM: 107039258
CCIN: 107268305
TCA: 107397949 655273
DPA: 109539855
SOY: 115891600
ATD: 109600572
CSET: 123310733
AGB: 108912049
LDC: 111504846
NVL: 108558843
PPYR: 116169542
OTU: 111419609
BMOR: 101744252
BMAN: 114249948
MSEX: 115448811
DPL: KGM_202174
BANY: 112058332
PMAC: 106707822
PPOT: 106111023
PXU: 106114758
PRAP: 110992313
ZCE: 119829857
HAW: 110376572 110376583 110376590
TNL: 113492944 113492945
OFU: 114355374
PXY: 105382561
API: 100161699
DNX: 107163062
AGS: 114123034
RMD: 113561352
BTAB: 109032361
DCI: 103516636
CLEC: 106663679
NLU: 111044266
PHU: Phum_PHUM176700
FOC: 113211545
ZNE: 110834851
CSEC: 111865456
FCD: 110854056
DPX: DAPPUDRAFT_247897(Adcy6) DAPPUDRAFT_318338
DMK: 116932776
PVM: 113803537
PJA: 122251535
HAME: 121876217
PCLA: 123766907
PTRU: 123515821
HAZT: 108672252
EAF: 111704198
DSV: 119448858
RSAN: 119381807
RMP: 119170587
TUT: 107365159
DPTE: 113796993
DFR: 124494863
PTEP: 107439048
SDM: 118184219
PMAX: 117316821
LAK: 106153878
AQU: 100637659
DFA: DFA_04345(acaA)
SPAR: SPRG_05070
 » show all
Reference
PMID:8076676
  Authors
Defer N, Marinx O, Stengel D, Danisova A, Iourgenko V, Matsuoka I, Caput D, Hanoune J
  Title
Molecular cloning of the human type VIII adenylyl cyclase.
  Journal
FEBS Lett 351:109-13 (1994)
DOI:10.1016/0014-5793(94)00836-1
  Sequence
[hsa:114]
Reference
PMID:21046358
  Authors
Roger B, Papin J, Vacher P, Raoux M, Mulot A, Dubois M, Kerr-Conte J, Voy BH, Pattou F, Charpentier G, Jonas JC, Moustaid-Moussa N, Lang J
  Title
Adenylyl cyclase 8 is central to glucagon-like peptide 1 signalling and effects of chronically elevated glucose in rat and human pancreatic beta cells.
  Journal
Diabetologia 54:390-402 (2011)
DOI:10.1007/s00125-010-1955-x
LinkDB

KEGG   ORTHOLOGY: K08049
Entry
K08049                      KO                                     
Symbol
ADCY9
Name
adenylate cyclase 9 [EC:4.6.1.1]
Pathway
map00230  Purine metabolism
map01100  Metabolic pathways
map01522  Endocrine resistance
map04015  Rap1 signaling pathway
map04020  Calcium signaling pathway
map04022  cGMP-PKG signaling pathway
map04024  cAMP signaling pathway
map04062  Chemokine signaling pathway
map04072  Phospholipase D signaling pathway
map04114  Oocyte meiosis
map04211  Longevity regulating pathway
map04213  Longevity regulating pathway - multiple species
map04261  Adrenergic signaling in cardiomyocytes
map04270  Vascular smooth muscle contraction
map04361  Axon regeneration
map04371  Apelin signaling pathway
map04540  Gap junction
map04611  Platelet activation
map04713  Circadian entrainment
map04714  Thermogenesis
map04723  Retrograde endocannabinoid signaling
map04724  Glutamatergic synapse
map04725  Cholinergic synapse
map04727  GABAergic synapse
map04750  Inflammatory mediator regulation of TRP channels
map04911  Insulin secretion
map04912  GnRH signaling pathway
map04913  Ovarian steroidogenesis
map04914  Progesterone-mediated oocyte maturation
map04915  Estrogen signaling pathway
map04916  Melanogenesis
map04918  Thyroid hormone synthesis
map04921  Oxytocin signaling pathway
map04923  Regulation of lipolysis in adipocytes
map04925  Aldosterone synthesis and secretion
map04926  Relaxin signaling pathway
map04927  Cortisol synthesis and secretion
map04928  Parathyroid hormone synthesis, secretion and action
map04934  Cushing syndrome
map04935  Growth hormone synthesis, secretion and action
map04961  Endocrine and other factor-regulated calcium reabsorption
map04962  Vasopressin-regulated water reabsorption
map04970  Salivary secretion
map04971  Gastric acid secretion
map04972  Pancreatic secretion
map04976  Bile secretion
map05032  Morphine addiction
map05110  Vibrio cholerae infection
map05163  Human cytomegalovirus infection
map05166  Human T-cell leukemia virus 1 infection
map05200  Pathways in cancer
map05207  Chemical carcinogenesis - receptor activation
map05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    K08049  ADCY9; adenylate cyclase 9
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    K08049  ADCY9; adenylate cyclase 9
   04371 Apelin signaling pathway
    K08049  ADCY9; adenylate cyclase 9
   04020 Calcium signaling pathway
    K08049  ADCY9; adenylate cyclase 9
   04072 Phospholipase D signaling pathway
    K08049  ADCY9; adenylate cyclase 9
   04024 cAMP signaling pathway
    K08049  ADCY9; adenylate cyclase 9
   04022 cGMP-PKG signaling pathway
    K08049  ADCY9; adenylate cyclase 9
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    K08049  ADCY9; adenylate cyclase 9
  09144 Cellular community - eukaryotes
   04540 Gap junction
    K08049  ADCY9; adenylate cyclase 9
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    K08049  ADCY9; adenylate cyclase 9
   04062 Chemokine signaling pathway
    K08049  ADCY9; adenylate cyclase 9
  09152 Endocrine system
   04911 Insulin secretion
    K08049  ADCY9; adenylate cyclase 9
   04923 Regulation of lipolysis in adipocytes
    K08049  ADCY9; adenylate cyclase 9
   04912 GnRH signaling pathway
    K08049  ADCY9; adenylate cyclase 9
   04913 Ovarian steroidogenesis
    K08049  ADCY9; adenylate cyclase 9
   04915 Estrogen signaling pathway
    K08049  ADCY9; adenylate cyclase 9
   04914 Progesterone-mediated oocyte maturation
    K08049  ADCY9; adenylate cyclase 9
   04921 Oxytocin signaling pathway
    K08049  ADCY9; adenylate cyclase 9
   04926 Relaxin signaling pathway
    K08049  ADCY9; adenylate cyclase 9
   04935 Growth hormone synthesis, secretion and action
    K08049  ADCY9; adenylate cyclase 9
   04918 Thyroid hormone synthesis
    K08049  ADCY9; adenylate cyclase 9
   04928 Parathyroid hormone synthesis, secretion and action
    K08049  ADCY9; adenylate cyclase 9
   04916 Melanogenesis
    K08049  ADCY9; adenylate cyclase 9
   04925 Aldosterone synthesis and secretion
    K08049  ADCY9; adenylate cyclase 9
   04927 Cortisol synthesis and secretion
    K08049  ADCY9; adenylate cyclase 9
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    K08049  ADCY9; adenylate cyclase 9
   04270 Vascular smooth muscle contraction
    K08049  ADCY9; adenylate cyclase 9
  09154 Digestive system
   04970 Salivary secretion
    K08049  ADCY9; adenylate cyclase 9
   04971 Gastric acid secretion
    K08049  ADCY9; adenylate cyclase 9
   04972 Pancreatic secretion
    K08049  ADCY9; adenylate cyclase 9
   04976 Bile secretion
    K08049  ADCY9; adenylate cyclase 9
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    K08049  ADCY9; adenylate cyclase 9
   04961 Endocrine and other factor-regulated calcium reabsorption
    K08049  ADCY9; adenylate cyclase 9
  09156 Nervous system
   04724 Glutamatergic synapse
    K08049  ADCY9; adenylate cyclase 9
   04727 GABAergic synapse
    K08049  ADCY9; adenylate cyclase 9
   04725 Cholinergic synapse
    K08049  ADCY9; adenylate cyclase 9
   04723 Retrograde endocannabinoid signaling
    K08049  ADCY9; adenylate cyclase 9
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    K08049  ADCY9; adenylate cyclase 9
  09158 Development and regeneration
   04361 Axon regeneration
    K08049  ADCY9; adenylate cyclase 9
  09149 Aging
   04211 Longevity regulating pathway
    K08049  ADCY9; adenylate cyclase 9
   04213 Longevity regulating pathway - multiple species
    K08049  ADCY9; adenylate cyclase 9
  09159 Environmental adaptation
   04713 Circadian entrainment
    K08049  ADCY9; adenylate cyclase 9
   04714 Thermogenesis
    K08049  ADCY9; adenylate cyclase 9
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K08049  ADCY9; adenylate cyclase 9
   05207 Chemical carcinogenesis - receptor activation
    K08049  ADCY9; adenylate cyclase 9
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K08049  ADCY9; adenylate cyclase 9
   05163 Human cytomegalovirus infection
    K08049  ADCY9; adenylate cyclase 9
  09171 Infectious disease: bacterial
   05110 Vibrio cholerae infection
    K08049  ADCY9; adenylate cyclase 9
  09165 Substance dependence
   05032 Morphine addiction
    K08049  ADCY9; adenylate cyclase 9
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    K08049  ADCY9; adenylate cyclase 9
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    K08049  ADCY9; adenylate cyclase 9
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    K08049  ADCY9; adenylate cyclase 9
Enzymes [BR:ko01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     K08049  ADCY9; adenylate cyclase 9
Other DBs
RN: R00089 R00434
GO: 0004016
Genes
HSA: 115(ADCY9)
PTR: 453869(ADCY9)
PPS: 100972356(ADCY9)
GGO: 101145410(ADCY9)
PON: 103889530(ADCY9)
NLE: 100599484(ADCY9)
MCC: 706789(ADCY9)
MCF: 102135923(ADCY9)
CSAB: 103227576(ADCY9)
CATY: 105572097(ADCY9)
PANU: 101004325(ADCY9)
TGE: 112614524(ADCY9)
RRO: 104672288(ADCY9)
RBB: 108538326(ADCY9)
TFN: 117097725(ADCY9)
PTEH: 111551667(ADCY9)
CJC: 100405403(ADCY9)
SBQ: 101052034(ADCY9)
CSYR: 103273680(ADCY9)
MMUR: 105859653(ADCY9)
OGA: 100943767(ADCY9)
MMU: 11515(Adcy9)
MCAL: 110311555(Adcy9)
MPAH: 110329624(Adcy9)
RNO: 302950(Adcy9)
MCOC: 116084214(Adcy9)
MUN: 110545944(Adcy9)
CGE: 100751372(Adcy9)
PLEU: 114710615(Adcy9)
NGI: 103744458(Adcy9)
HGL: 101714605(Adcy9)
CPOC: 100717226(Adcy9)
CCAN: 109681681 109681696
DORD: 105981874(Adcy9)
DSP: 122123783(Adcy9)
OCU: 100340877(ADCY9)
OPI: 101517485(ADCY9)
TUP: 102477344(ADCY9)
CFA: 490031(ADCY9)
VVP: 112923266(ADCY9)
VLG: 121486234(ADCY9)
AML: 100476495(ADCY9)
UMR: 103668547(ADCY9)
UAH: 113270857(ADCY9)
UAR: 123783548(ADCY9)
ELK: 111156133
LLV: 125091072
MPUF: 101680942(ADCY9)
ORO: 101364108(ADCY9)
EJU: 114219898(ADCY9)
ZCA: 113932237(ADCY9)
MLX: 118021775(ADCY9)
FCA: 101095942(ADCY9)
PYU: 121019600(ADCY9)
PBG: 122471737(ADCY9)
PTG: 102969003(ADCY9)
PPAD: 109278247(ADCY9)
AJU: 106978803(ADCY9)
HHV: 120236476(ADCY9)
BTA: 525482(ADCY9)
BOM: 102285642(ADCY9)
BIU: 109578364(ADCY9)
BBUB: 102404282(ADCY9)
CHX: 102188104(ADCY9)
OAS: 101122401(ADCY9)
ODA: 120874335(ADCY9)
CCAD: 122432769(ADCY9)
SSC: 100625423(ADCY9)
CFR: 102505261(ADCY9)
CBAI: 105064797(ADCY9)
CDK: 105099828(ADCY9)
VPC: 102535401(ADCY9)
BACU: 103016058(ADCY9)
LVE: 103070451(ADCY9)
OOR: 101281654(ADCY9)
DLE: 111185250(ADCY9)
PCAD: 102995803(ADCY9)
PSIU: 116740403(ADCY9)
ECB: 100066046(ADCY9)
EPZ: 103553014(ADCY9)
EAI: 106826021(ADCY9)
MYB: 102248953(ADCY9)
MYD: 102760324(ADCY9)
MMYO: 118656939(ADCY9)
MLF: 102422477(ADCY9)
MNA: 107535777(ADCY9)
PKL: 118703343(ADCY9)
HAI: 109392133(ADCY9)
DRO: 112298360(ADCY9)
SHON: 118975805(ADCY9)
AJM: 119056281(ADCY9)
PDIC: 114503776 114505902(ADCY9)
PHAS: 123807136(ADCY9)
MMF: 118642221(ADCY9)
RFQ: 117019474(ADCY9)
PALE: 102885676(ADCY9)
PGIG: 120620331(ADCY9)
PVP: 105303095(ADCY9)
RAY: 107521680(ADCY9)
MJV: 108384867 108406458(ADCY9)
TOD: 119241983(ADCY9)
SARA: 101551730(ADCY9)
LAV: 100663448(ADCY9)
TMU: 101344705
DNM: 101442901(ADCY9)
MDO: 100013831(ADCY9)
GAS: 123231736(ADCY9)
SHR: 100926025(ADCY9)
PCW: 110214660(ADCY9)
OAA: 100080569(ADCY9)
GGA: 395339(ADCY9)
PCOC: 116230251(ADCY9)
MGP: 100542393 104913356
CJO: 107320968(ADCY9)
NMEL: 110405807(ADCY9)
APLA: 101800617(ADCY9)
ACYG: 106033354(ADCY9)
AFUL: 116495186(ADCY9)
TGU: 100231171(ADCY9)
LSR: 110476108(ADCY9)
SCAN: 103817765(ADCY9)
PMOA: 120513041(ADCY9)
OTC: 121338477(ADCY9)
PRUF: 121350906(ADCY9)
GFR: 102043312(ADCY9)
FAB: 101818533(ADCY9)
PHI: 102103610(ADCY9)
PMAJ: 107211136(ADCY9)
CCAE: 111935874(ADCY9)
CCW: 104684954(ADCY9)
ETL: 114057021(ADCY9)
ZAB: 102065721(ADCY9)
FPG: 101921768(ADCY9)
FCH: 102047847(ADCY9)
CLV: 102095574(ADCY9)
EGZ: 104121973(ADCY9)
NNI: 104023465(ADCY9)
ACUN: 113485514(ADCY9)
TALA: 104366998(ADCY9)
PADL: 103917604(ADCY9)
ACHC: 115336030(ADCY9)
AAM: 106482327(ADCY9)
AROW: 112965855(ADCY9)
NPD: 112955683(ADCY9)
DNE: 112986919(ADCY9)
ASN: 102370673 102373860(ADCY9)
AMJ: 102574362(ADCY9)
CPOO: 109313447(ADCY9)
GGN: 109290787(ADCY9)
PSS: 102448197(ADCY9)
CMY: 102945804(ADCY9)
CPIC: 101940138(ADCY9)
TST: 117883930(ADCY9)
CABI: 116825535(ADCY9)
MRV: 120373164(ADCY9)
ACS: 100556223(adcy9)
PVT: 110089110(ADCY9)
SUND: 121914170(ADCY9)
PBI: 103051661(ADCY9)
PMUR: 107283963(ADCY9)
TSR: 106551564(ADCY9)
PGUT: 117679454(ADCY9)
VKO: 123025128(ADCY9)
PMUA: 114584296(ADCY9)
ZVI: 118092905(ADCY9)
GJA: 107109291(ADCY9)
XLA: 108703189(adcy9.S) 378610(adcy9.L)
XTR: 100126441(adcy9)
NPR: 108790811(ADCY9)
RTEM: 120943333(ADCY9)
BBUF: 121008967(ADCY9)
BGAR: 122944479(ADCY9)
DRE: 100333702(adcy9) 101884360
SRX: 107715643 107718568 107742090 107755348
SANH: 107655369 107659321 107661757 107695715
SGH: 107553626 107566051 107566672 107601541(adcy9)
CCAR: 109046870 109046899(adcy9)
CAUA: 113039957 113051739 113065061 113067623
IPU: 108259388(adcy9)
PHYP: 113547577
SMEO: 124379699(adcy9)
AMEX: 103022434(adcy9)
EEE: 113576829 113580690
TRU: 101074204 101078598(adcy9)
TNG: GSTEN00026314G001 GSTEN00026315G001
LCO: 104925375 104925703(adcy9)
NCC: 104952968 104960152 104960179
CGOB: 115011853(adcy9) 115019777
ELY: 117255130(adcy9) 117268794
PLEP: 121941820(adcy9) 121956605
SLUC: 116042792(adcy9) 116059342
ECRA: 117954726(adcy9) 117958663
PFLV: 114565456 114569437(adcy9)
GAT: 120825138(adcy9) 120827674
PPUG: 119218113(adcy9) 119220190
MSAM: 119889816 119899433(adcy9)
CUD: 121507894(adcy9) 121529451
MZE: 101466373 101477119(adcy9)
ONL: 100703903(adcy9) 100710254
OAU: 116310579(adcy9) 116321439
OLA: 101155516(adcy9) 101163149
OML: 112137465(adcy9) 112146809
XMA: 102230840(adcy9) 102231255
XCO: 114144541 114160082(adcy9)
XHE: 116719875 116735712(adcy9)
PRET: 103464021 103469190(adcy9)
PFOR: 103131040 103141004 103154140
PLAI: 106942578(adcy9) 106945964
PMEI: 106915777 106922027 106933946
GAF: 122821683 122829319(adcy9)
CVG: 107083431 107095220(adcy9)
CTUL: 119773188 119798032
GMU: 124862755 124864776 124867768(adcy9)
NFU: 107376487(adcy9) 107390534
KMR: 108241462(adcy9) 108247648
ALIM: 106518708(adcy9) 106532502
NWH: 119420989 119423075(adcy9)
AOCE: 111569892 111582512
CSEM: 103384091 103393051(adcy9)
POV: 109627430 109638721
SSEN: 122771216(adcy9) 122784928
HHIP: 117761437(adcy9) 117766860
LCF: 108885408 108886159(adcy9)
SDU: 111227004(adcy9) 111229246
SLAL: 111665544 111667563(adcy9)
XGL: 120783409 120799900(adcy9)
HCQ: 109527326 109532550(adcy9)
BPEC: 110166178 110168281(adcy9)
MALB: 109972278 109972902(adcy9)
SASA: 106564461 106564466 106590289 106590466 106601887 106601890 106606489(adcy9)
OTW: 112238377(adcy9) 112240731
OMY: 110485545 110516720 110539056 118938426
OGO: 123999196 124016520(adcy9)
SALP: 112074752
SNH: 120017568 120032464 120044084
ELS: 105012108 105021646
SFM: 108928849(adcy9) 108930202
PKI: 111843208(adcy9) 111860576
AANG: 118217014 118219851
LOC: 102695743(adcy9)
PSPA: 121300452 121330489
ARUT: 117418288 117431652(adcy9)
LCM: 102363182(ADCY9)
CMK: 103178726(adcy9)
RTP: 109913552 109932682(adcy9)
BFO: 118419128
BBEL: 109470759
CIN: 100176999
SCLV: 120340982
SPU: 115918037
APLC: 110976938
DME: Dmel_CG9210(Ac13E)
DER: 6550781
DSE: 6620492
DSI: Dsimw501_GD27717(Dsim_GD27717)
DYA: Dyak_GE16042
DAN: 6504918
DSR: 110179465
DPO: Dpse_GA21615
DPE: 6600185
DMN: 108162824
DWI: 6641108
DGR: 6565535
DMO: Dmoj_GI15443
DAZ: 108618258
DNV: 108657257
DHE: 111593022
DVI: 6632141
CCAT: 101454975
BOD: 106627061
MDE: 101898652
SCAC: 106094127
LCQ: 111674878
AGA: AgaP_AGAP000090
ACOZ: 120960963
AARA: 120905622
AAG: 23687681
AALB: 109401910
CQU: CpipJ_CPIJ017308
CPII: 120416886
CNS: 116347550
AME: 552535
ACER: 107997752
ALAB: 122716251
BIM: 100746561
BBIF: 117208810
BVK: 117231486
BVAN: 117156886
BTER: 100651494
BPYO: 122572676
CCAL: 108624324
OBB: 114880536
MGEN: 117225285
NMEA: 116429546
CGIG: 122404520
SOC: 105198643
MPHA: 105838352
AEC: 105150701
ACEP: 105627205
PBAR: 105427028
VEM: 105564754
HST: 105181099
DQU: 106747283
CFO: 105256088
FEX: 115243591
LHU: 105677518
PGC: 109854881
PCF: 106790513
PFUC: 122521303
VPS: 122637861
NVI: 100119583
CSOL: 105363461
TPRE: 106651218
MDL: 103571696
CGLO: 123272289
FAS: 105268508
DAM: 107042438
AGIF: 122859433
CCIN: 107272739
TCA: 663450
DPA: 109540821 109543014 109546437
SOY: 115888190
ATD: 109602330
CSET: 123308982
AGB: 108914929
LDC: 111503657
NVL: 108565010
APLN: 108738447
PPYR: 116177917
OTU: 111422488 111423681
BMOR: 101739269
BMAN: 114241715
MSEX: 115445816 119190145
DPL: KGM_211881
BANY: 112054500
PMAC: 106721760
PPOT: 106103338
PXU: 106123447
PRAP: 110992828
ZCE: 119833421
HAW: 110378429
TNL: 113507970
OFU: 114361142
PXY: 105390863
BTAB: 109032478
CLEC: 106670008
HHAL: 106686877
NLU: 111052708
PHU: Phum_PHUM155150
FOC: 113214351
ZNE: 110827835
CSEC: 111861375
DPX: DAPPUDRAFT_302912
DMK: 116915808
PVM: 113829994
PJA: 122250771
HAME: 121871881
PCLA: 123760662
PTRU: 123506767
HAZT: 108673638
EAF: 111705863
ISC: IscW_ISCW021824
DSV: 119449545
RSAN: 119382569
RMP: 119179607
VDE: 111243249
VJA: 111263474 111267788
CSCU: 111635808
CEL: CELE_F17C8.1(acy-1)
CBR: CBG_18000(Cbr-acy-1)
BMY: BM_BM3414(Bma-acy-1)
LOA: LOAG_11276
NAI: NECAME_02871
TSP: Tsp_06467 Tsp_06476
LGI: LOTGIDRAFT_136233
PCAN: 112558934
BGT: 106058937
GAE: 121375216
HRF: 124139610
HRJ: 124280216
CRG: 105335675
MYI: 110461839
PMAX: 117329864
MMER: 123556748
LAK: 106155533 106170328
SMM: Smp_102340.1
OVI: T265_02194 T265_02366 T265_04534 T265_06551
EGL: EGR_00868 EGR_01141 EGR_01447
NVE: 5519173
EPA: 110248954
ATEN: 116296067
ADF: 107348722
AMIL: 114950775
PDAM: 113676812
SPIS: 111327491
DGT: 114524446
XEN: 124445488
HMG: 100204733 100209499
TAD: TRIADDRAFT_31746
AQU: 100641421
 » show all
Reference
PMID:9628827
  Authors
Hacker BM, Tomlinson JE, Wayman GA, Sultana R, Chan G, Villacres E, Disteche C, Storm DR
  Title
Cloning, chromosomal mapping, and regulatory properties of the human type 9 adenylyl cyclase (ADCY9).
  Journal
Genomics 50:97-104 (1998)
DOI:10.1006/geno.1998.5293
  Sequence
[hsa:115]
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