KEGG Orthology (KO) - Acinonyx jubatus (cheetah)

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     KO
 09100 Metabolism
 
 09120 Genetic Information Processing
 
 09130 Environmental Information Processing
 
 09140 Cellular Processes
 
   09141 Transport and catabolism
 
   09143 Cell growth and death
     04110 Cell cycle [PATH:aju04110]
     04111 Cell cycle - yeast
     04112 Cell cycle - Caulobacter
     04113 Meiosis - yeast
     04114 Oocyte meiosis [PATH:aju04114]
     04210 Apoptosis [PATH:aju04210]
       106990055 TNFSF10; tumor necrosis factor ligand superfamily member 10
       106979842 FASLG; tumor necrosis factor ligand superfamily member 6
       106980953 FAS; tumor necrosis factor receptor superfamily member 6 isoform X1
       106982870 FADD; FAS-associated death domain protein
       106983958 TNF; tumor necrosis factor
       106965450 TNFRSF1A; tumor necrosis factor receptor superfamily member 1A isoform X1
       106971422 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
       106987988 CFLAR; CASP8 and FADD-like apoptosis regulator isoform X1
       106987995 CASP8; caspase-8
       106987987 CASP10; caspase-10 isoform X1
       106983648 PLA2G12A; group XIIA secretory phospholipase A2 isoform X1
       106979326 CASP3; caspase-3 isoform X1
       106974123 CASP7; caspase-7 isoform X1
       106968455 BID; BH3-interacting domain death agonist
       106988699 BAX; apoptosis regulator BAX isoform X1
       106976101 BAK1; bcl-2 homologous antagonist/killer
       106967598 DIABLO; diablo homolog, mitochondrial
       106989946 SEPT4; septin-4 isoform X1
       113592650 CUNH17orf47; uncharacterized protein C17orf47 homolog
       106988577 HTRA2; serine protease HTRA2, mitochondrial isoform X1
       106988781 cytochrome c
       106982840 cytochrome c
       106986613 cytochrome c-like
       106973746 APAF1; apoptotic protease-activating factor 1 isoform X1
       106975594 CASP9; caspase-9 isoform X1
       106967198 PRF1; perforin-1 isoform X1
       106987873 mast cell protease 1A-like isoform X1
       106987852 granzyme B(G
       106969282 TUBA1B; tubulin alpha-1B chain isoform X1
       106969285 tubulin alpha-1C chain
       106968459 TUBA8; tubulin alpha-8 chain
       106972801 LOW QUALITY PROTEIN: tubulin alpha-8 chain
       106983635 tubulin alpha-3 chain
       106988132 TUBAL3; tubulin alpha chain-like 3
       106970047 tubulin alpha-4A chain
       106969284 tubulin alpha-1A chain
       106986653 MCL1; induced myeloid leukemia cell differentiation protein Mcl-1
       106987399 ACTG1; actin, cytoplasmic 2
       106984514 ACTB; actin, cytoplasmic 1
       106966268 SPTAN1; spectrin alpha chain, non-erythrocytic 1 isoform X1
       106987155 SPTA1; spectrin alpha chain, erythrocytic 1
       106981532 LMNA; lamin
       106989696 LMNB2; lamin-B2 isoform X1
       106970739 LMNB1; lamin-B1
       106968624 PARP1; poly [ADP-ribose] polymerase 1 isoform X1
       106971396 PARP2; poly [ADP-ribose] polymerase 2 isoform X1
       106979809 PARP4; poly [ADP-ribose] polymerase 4 isoform X1
       106987012 PARP3; poly [ADP-ribose] polymerase 3
       106984923 DFFA; DNA fragmentation factor subunit alpha isoform X1
       106975297 DFFB; DNA fragmentation factor subunit beta isoform X1
       106966261 ENDOG; endonuclease G, mitochondrial
       106981569 AIFM1; apoptosis-inducing factor 1, mitochondrial isoform X1
       106978670 ERN1; serine/threonine-protein kinase/endoribonuclease IRE1 isoform X1
       106989490 TRAF2; TNF receptor-associated factor 2 isoform X1
       106978946 ITPR1; inositol 1,4,5-trisphosphate receptor type 1 isoform X1
       106968786 ITPR2; inositol 1,4,5-trisphosphate receptor type 2 isoform X1
       106976077 ITPR3; inositol 1,4,5-trisphosphate receptor type 3 isoform X1
       106971147 CAPN1; calpain-1 catalytic subunit
       106983173 CAPN2; calpain-2 catalytic subunit
       106976502 caspase-12-like isoform X1
       106978143 EIF2AK3; eukaryotic translation initiation factor 2-alpha kinase 3 isoform X1
       106971552 EIF2S1; eukaryotic translation initiation factor 2 subunit 1
       106979942 ATF4; cyclic AMP-dependent transcription factor ATF-4
       106975861 DDIT3; DNA damage-inducible transcript 3 protein
       106975817 CTSB; cathepsin B isoform X1
       106967745 CTSC; dipeptidyl peptidase 1 isoform X1
       106972633 LOW QUALITY PROTEIN: dipeptidyl peptidase 1-like
       106971074 CTSD; cathepsin D
       106971117 CTSF; cathepsin F
       106988474 CTSH; pro-cathepsin H isoform X1
       106979872 CTSK; cathepsin K
       106971464 cathepsin L1-like
       106971475 LOW QUALITY PROTEIN: cathepsin L1-like
       106971491 cathepsin L1
       106971473 cathepsin L1-like
       113596115 cathepsin L1-like
       106971463 cathepsin L1-like isoform X1
       113596116 LOW QUALITY PROTEIN: cathepsin L1-like
       106971474 cathepsin L1-like
       106971459 LOW QUALITY PROTEIN: cathepsin L1-like
       106982439 CTSO; cathepsin O
       106979853 CTSS; cathepsin S isoform X1
       106971131 CTSW; cathepsin W isoform X1
       106969919 CTSZ; cathepsin Z
       106976507 baculoviral IAP repeat-containing protein 3-like
       106976508 BIRC2; baculoviral IAP repeat-containing protein 2
       106972832 XIAP; E3 ubiquitin-protein ligase XIAP
       106981916 BIRC5; baculoviral IAP repeat-containing protein 5 isoform X1
       106976034 BCL2L11; bcl-2-like protein 11 isoform X1
       106986010 BCL2L1; bcl-2-like protein 1
       106985187 BCL2; apoptosis regulator Bcl-2
       106976080 DAXX; death domain-associated protein 6
       106976163 RIPK1; receptor-interacting serine/threonine-protein kinase 1
       106986610 DAB2IP; LOW QUALITY PROTEIN: disabled homolog 2-interacting protein
       106983673 MAP3K5; mitogen-activated protein kinase kinase kinase 5 isoform X1
       106969894 MAPK9; mitogen-activated protein kinase 9 isoform X1
       106970668 MAPK10; mitogen-activated protein kinase 10 isoform X2
       106989581 MAPK8; mitogen-activated protein kinase 8 isoform X1
       106981699 BAD; bcl2-associated agonist of cell death
       106974986 JUN; transcription factor AP-1
       106974355 FOS; proto-oncogene c-Fos
       106972437 TP53; cellular tumor antigen p53
       113595095 HRK; activator of apoptosis harakiri
       106988147 MAP3K14; mitogen-activated protein kinase kinase kinase 14
       106966935 CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X3
       106990012 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1
       106988817 IKBKG; NF-kappa-B essential modulator isoform X1
       106965509 NFKBIA; NF-kappa-B inhibitor alpha
       106984704 NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1
       106971136 RELA; transcription factor p65
       106970662 PTPN13; tyrosine-protein phosphatase non-receptor type 13 isoform X2
       106989693 GADD45B; growth arrest and DNA damage-inducible protein GADD45 beta
       106985200 GADD45A; growth arrest and DNA damage-inducible protein GADD45 alpha
       113594268 GADD45G; growth arrest and DNA damage-inducible protein GADD45 gamma
       106986638 TRAF1; TNF receptor-associated factor 1 isoform X1
       106988491 bcl-2-related protein A1 isoform X2
       106983963 ATM; serine-protein kinase ATM isoform X1
       106988898 PIDD1; p53-induced death domain-containing protein 1 isoform X1
       106973568 BBC3; bcl-2-binding component 3
       106978896 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
       106980767 CASP2; caspase-2 isoform X1
       106969645 NGF; beta-nerve growth factor
       106988854 NTRK1; high affinity nerve growth factor receptor
       113604567 IL3; interleukin-3
       113597168 IL3RA; LOW QUALITY PROTEIN: interleukin-3 receptor subunit alpha
       106981032 CSF2RB; cytokine receptor common subunit beta
       106984896 PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1
       106984265 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
       106973880 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
       106976917 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1
       106973297 PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma
       106969150 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
       106978772 PDPK1; 3-phosphoinositide-dependent protein kinase 1 isoform X4
       106979622 AKT2; RAC-beta serine/threonine-protein kinase isoform X1
       106975558 AKT3; RAC-gamma serine/threonine-protein kinase isoform X2
       106985046 AKT1; RAC-alpha serine/threonine-protein kinase isoform X1
       106987957 HRAS; GTPase HRas isoform X1
       106968778 KRAS; GTPase KRas isoform X1
       106969596 NRAS; GTPase NRas
       106977129 RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X1
       106980282 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 isoform X2
       106975474 MAP2K2; dual specificity mitogen-activated protein kinase kinase 2 isoform X1
       106969232 MAPK3; mitogen-activated protein kinase 3 isoform X2
       106990008 MAPK1; mitogen-activated protein kinase 1
K04721 TNFSF10; tumor necrosis factor ligand superfamily member 10
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K03156 TNF; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A; tumor necrosis factor receptor superfamily member 1A
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K04724 CFLAR; CASP8 and FADD-like apoptosis regulator
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04400 CASP10; caspase 10 [EC:3.4.22.63]
K04396 CASP6; caspase 6 [EC:3.4.22.59]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04397 CASP7; caspase 7 [EC:3.4.22.60]
K04726 BID; BH3 interacting domain death agonist
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K10522 DIABLO; diablo
K16943 SEPT4; septin 4
K16943 SEPT4; septin 4
K08669 HTRA2; HtrA serine peptidase 2 [EC:3.4.21.108]
K08738 CYC; cytochrome c
K08738 CYC; cytochrome c
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K07818 PRF1; perforin 1
K01353 GZMB; granzyme B [EC:3.4.21.79]
K01353 GZMB; granzyme B [EC:3.4.21.79]
K07374 TUBA; tubulin alpha
K07374 TUBA; tubulin alpha
K07374 TUBA; tubulin alpha
K07374 TUBA; tubulin alpha
K07374 TUBA; tubulin alpha
K07374 TUBA; tubulin alpha
K07374 TUBA; tubulin alpha
K07374 TUBA; tubulin alpha
K02539 MCL1; myeloid leukemia cell differntiation protein MCL-1
K05692 ACTB_G1; actin beta/gamma 1
K05692 ACTB_G1; actin beta/gamma 1
K06114 SPTA; spectrin alpha
K06114 SPTA; spectrin alpha
K12641 LMNA; lamin A/C
K07611 LMNB; lamin B
K07611 LMNB; lamin B
K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
K02310 DFFA; DNA fragmentation factor, 45 kD, alpha subunit
K02311 DFFB; DNA fragmentation factor, 40 kD, beta subunit [EC:3.-.-.-]
K01173 ENDOG; endonuclease G, mitochondrial
K04727 AIFM1; apoptosis-inducing factor 1 [EC:1.-.-.-]
K08852 ERN1; serine/threonine-protein kinase/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-]
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K01367 CAPN1; calpain-1 [EC:3.4.22.52]
K03853 CAPN2; calpain-2 [EC:3.4.22.53]
K04741 CASP12; caspase 12 [EC:3.4.22.-]
K08860 EIF2AK3; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
K03237 EIF2S1; translation initiation factor 2 subunit 1
K04374 ATF4; cyclic AMP-dependent transcription factor ATF-4
K04452 DDIT3; DNA damage-inducible transcript 3
K01363 CTSB; cathepsin B [EC:3.4.22.1]
K01275 CTSC; cathepsin C [EC:3.4.14.1]
K01275 CTSC; cathepsin C [EC:3.4.14.1]
K01379 CTSD; cathepsin D [EC:3.4.23.5]
K01373 CTSF; cathepsin F [EC:3.4.22.41]
K01366 CTSH; cathepsin H [EC:3.4.22.16]
K01371 CTSK; cathepsin K [EC:3.4.22.38]
K01365 CTSL; cathepsin L [EC:3.4.22.15]
K01365 CTSL; cathepsin L [EC:3.4.22.15]
K01365 CTSL; cathepsin L [EC:3.4.22.15]
K01365 CTSL; cathepsin L [EC:3.4.22.15]
K01365 CTSL; cathepsin L [EC:3.4.22.15]
K01365 CTSL; cathepsin L [EC:3.4.22.15]
K01365 CTSL; cathepsin L [EC:3.4.22.15]
K01365 CTSL; cathepsin L [EC:3.4.22.15]
K01365 CTSL; cathepsin L [EC:3.4.22.15]
K01374 CTSO; cathepsin O [EC:3.4.22.42]
K01368 CTSS; cathepsin S [EC:3.4.22.27]
K08569 CTSW; cathepsin W [EC:3.4.22.-]
K08568 CTSZ; cathepsin X [EC:3.4.18.1]
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04725 XIAP; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K08731 BIRC5; baculoviral IAP repeat-containing protein 5
K16341 BCL2L11; Bcl-2-like protein 11
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K02161 BCL2; apoptosis regulator Bcl-2
K02308 DAXX; death-associated protein 6
K02861 RIPK1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
K19901 DAB2IP; disabled homolog 2-interacting protein
K04426 MAP3K5; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K02158 BAD; Bcl-2-antagonist of cell death
K04448 JUN; transcription factor AP-1
K04379 FOS; proto-oncogene protein c-fos
K04451 TP53; tumor protein p53
K02512 HRK; activator of apoptosis harakiri
K04466 MAP3K14; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K02374 PTPN13; tyrosine-protein phosphatase non-receptor type 13
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K03172 TRAF1; TNF receptor-associated factor 1
K02162 BCL2A1; hematopoietic Bcl-2-related protein A1
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K10130 LRDD; leucine-rich repeats and death domain-containing protein
K10132 BBC3; Bcl-2-binding component 3
K10131 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
K02186 CASP2; caspase 2 [EC:3.4.22.55]
K02582 NGFB; nerve growth factor, beta
K03176 NTRK1; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K04736 IL3; interleukin 3
K04737 IL3RA; interleukin 3 receptor alpha
K04738 CSF2RB; cytokine receptor common subunit beta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
     04214 Apoptosis - fly
     04215 Apoptosis - multiple species [PATH:aju04215]
       106965450 TNFRSF1A; tumor necrosis factor receptor superfamily member 1A isoform X1
       106982870 FADD; FAS-associated death domain protein
       106987995 CASP8; caspase-8
       106974123 CASP7; caspase-7 isoform X1
       106979326 CASP3; caspase-3 isoform X1
       106968455 BID; BH3-interacting domain death agonist
       106976034 BCL2L11; bcl-2-like protein 11 isoform X1
       106978896 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
       106973568 BBC3; bcl-2-binding component 3
       106985187 BCL2; apoptosis regulator Bcl-2
       106986010 BCL2L1; bcl-2-like protein 1
       106988699 BAX; apoptosis regulator BAX isoform X1
       106976101 BAK1; bcl-2 homologous antagonist/killer
       106988781 cytochrome c
       106982840 cytochrome c
       106986613 cytochrome c-like
       106973746 APAF1; apoptotic protease-activating factor 1 isoform X1
       106975594 CASP9; caspase-9 isoform X1
       106967598 DIABLO; diablo homolog, mitochondrial
       106988577 HTRA2; serine protease HTRA2, mitochondrial isoform X1
       106989946 SEPT4; septin-4 isoform X1
       113592650 CUNH17orf47; uncharacterized protein C17orf47 homolog
       106976507 baculoviral IAP repeat-containing protein 3-like
       106976508 BIRC2; baculoviral IAP repeat-containing protein 2
       106972832 XIAP; E3 ubiquitin-protein ligase XIAP
       106981916 BIRC5; baculoviral IAP repeat-containing protein 5 isoform X1
       106969894 MAPK9; mitogen-activated protein kinase 9 isoform X1
       106970668 MAPK10; mitogen-activated protein kinase 10 isoform X2
       106989581 MAPK8; mitogen-activated protein kinase 8 isoform X1
       106984594 BOK; bcl-2-related ovarian killer protein isoform X1
       106973711 BIRC7; baculoviral IAP repeat-containing protein 7
       106985158 NGFR; tumor necrosis factor receptor superfamily member 16
       106972618 BECN1; beclin-1 isoform X1
       106975548 BECN2; beclin-2
       106967931 BIRC6; baculoviral IAP repeat-containing protein 6 isoform X1
K03158 TNFRSF1A; tumor necrosis factor receptor superfamily member 1A
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04397 CASP7; caspase 7 [EC:3.4.22.60]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04726 BID; BH3 interacting domain death agonist
K16341 BCL2L11; Bcl-2-like protein 11
K10131 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
K10132 BBC3; Bcl-2-binding component 3
K02161 BCL2; apoptosis regulator Bcl-2
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K08738 CYC; cytochrome c
K08738 CYC; cytochrome c
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K10522 DIABLO; diablo
K08669 HTRA2; HtrA serine peptidase 2 [EC:3.4.21.108]
K16943 SEPT4; septin 4
K16943 SEPT4; septin 4
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04725 XIAP; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K08731 BIRC5; baculoviral IAP repeat-containing protein 5
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K02561 BOK; Bcl-2-related ovarian killer protein
K16061 BIRC7_8; baculoviral IAP repeat-containing protein 7/8
K02583 NGFR; tumor necrosis factor receptor superfamily member 16
K08334 BECN; beclin
K08334 BECN; beclin
K10586 BIRC6; baculoviral IAP repeat-containing protein 6 (apollon) [EC:2.3.2.23]
     04216 Ferroptosis [PATH:aju04216]
     04217 Necroptosis [PATH:aju04217]
     04115 p53 signaling pathway [PATH:aju04115]
       106983963 ATM; serine-protein kinase ATM isoform X1
       106985461 CHEK2; serine/threonine-protein kinase Chk2 isoform X3
       106982261 ATR; serine/threonine-protein kinase ATR isoform X1
       106976641 CHEK1; serine/threonine-protein kinase Chk1
       106966200 GORAB; RAB6-interacting golgin isoform X1
       106986386 cyclin-dependent kinase inhibitor 2A-like
       106966348 MDM2; E3 ubiquitin-protein ligase Mdm2 isoform X3
       106972905 MDM4; protein Mdm4
       106972437 TP53; cellular tumor antigen p53
       106972797 CDKN1A; cyclin-dependent kinase inhibitor 1
       106971167 CCND1; G1/S-specific cyclin-D1
       106965383 CCND2; G1/S-specific cyclin-D2
       106974052 CCND3; G1/S-specific cyclin-D3 isoform X2
       106975871 CDK4; cyclin-dependent kinase 4 isoform X1
       106969949 CDK6; cyclin-dependent kinase 6
       106974883 CCNE2; G1/S-specific cyclin-E2 isoform X1
       106975766 CCNE1; G1/S-specific cyclin-E1
       106986916 CDK2; cyclin-dependent kinase 2 isoform X1
       106977554 SFN; 14-3-3 protein sigma
       113598220 RPRM; protein reprimo
       106977069 CCNB1; G2/mitotic-specific cyclin-B1
       106973791 CCNB2; G2/mitotic-specific cyclin-B2 isoform X2
       106989884 CDK1; cyclin-dependent kinase 1
       106989693 GADD45B; growth arrest and DNA damage-inducible protein GADD45 beta
       106985200 GADD45A; growth arrest and DNA damage-inducible protein GADD45 alpha
       113594268 GADD45G; growth arrest and DNA damage-inducible protein GADD45 gamma
       106967293 GTSE1; G2 and S phase-expressed protein 1 isoform X3
       106980953 FAS; tumor necrosis factor receptor superfamily member 6 isoform X1
       106988898 PIDD1; p53-induced death domain-containing protein 1 isoform X1
       106987995 CASP8; caspase-8
       106968455 BID; BH3-interacting domain death agonist
       106988699 BAX; apoptosis regulator BAX isoform X1
       106978896 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
       106973568 BBC3; bcl-2-binding component 3
       106985053 SIVA1; apoptosis regulatory protein Siva isoform X1
       106986010 BCL2L1; bcl-2-like protein 1
       106985187 BCL2; apoptosis regulator Bcl-2
       106986711 TP53I3; quinone oxidoreductase PIG3 isoform X1
       106976643 EI24; etoposide-induced protein 2.4 homolog
       106979214 SHISA5; protein shisa-5 isoform X3
       106982024 PERP; p53 apoptosis effector related to PMP-22
       106973879 ZMAT3; zinc finger matrin-type protein 3 isoform X1
       106985846 SIAH1; E3 ubiquitin-protein ligase SIAH1 isoform X1
       106982593 E3 ubiquitin-protein ligase SIAH1-like
       106988781 cytochrome c
       106982840 cytochrome c
       106986613 cytochrome c-like
       106973746 APAF1; apoptotic protease-activating factor 1 isoform X1
       106975594 CASP9; caspase-9 isoform X1
       106979326 CASP3; caspase-3 isoform X1
       106967155 AIFM2; apoptosis-inducing factor 2 isoform X1
       106968195 IGFBP3; insulin-like growth factor-binding protein 3
       106971906 IGF1; insulin-like growth factor I isoform X1
       106988114 SERPINE1; plasminogen activator inhibitor 1
       113600537 ADGRB1; adhesion G protein-coupled receptor B1
       106978048 CD82; CD82 antigen
       106979757 THBS1; thrombospondin-1
       106985014 SERPINB5; serpin B5
       106978021 DDB2; DNA damage-binding protein 2 isoform X1
       106980049 RRM2B; ribonucleoside-diphosphate reductase subunit M2 B
       106987069 RRM2; ribonucleoside-diphosphate reductase subunit M2 isoform X1
       106986954 SESN3; sestrin-3
       106968884 SESN1; sestrin-1 isoform X1
       106977533 SESN2; sestrin-2
       106980972 PTEN; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X3
       106982748 TSC2; tuberin isoform X1
       106966428 STEAP3; metalloreductase STEAP3 isoform X1
       106967964 COP1; E3 ubiquitin-protein ligase COP1 isoform X1
       106981721 RCHY1; RING finger and CHY zinc finger domain-containing protein 1 isoform X1
       106970382 CCNG1; cyclin-G1
       106981545 CCNG2; cyclin-G2
       106972698 PPM1D; protein phosphatase 1D
       106975286 TP73; tumor protein p73 isoform X1
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
K19748 GORAB; RAB6-interacting golgin
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K10127 MDM4; protein Mdm4
K04451 TP53; tumor protein p53
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06644 SFN; stratifin
K10128 RPRM; reprimo, TP53-dependent G2 arrest mediator candidate
K05868 CCNB1; G2/mitotic-specific cyclin-B1
K21770 CCNB2; G2/mitotic-specific cyclin-B2
K02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K10129 GTSE1; G-2 and S-phase expressed protein 1
K04390 TNFRSF6; tumor necrosis factor receptor superfamily member 6
K10130 LRDD; leucine-rich repeats and death domain-containing protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K02159 BAX; apoptosis regulator BAX
K10131 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
K10132 BBC3; Bcl-2-binding component 3
K22744 SIVA1; apoptosis regulatory protein Siva
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K02161 BCL2; apoptosis regulator Bcl-2
K10133 TP53I3; tumor protein p53-inducible protein 3 [EC:1.-.-.-]
K10134 EI24; etoposide-induced 2.4 mRNA
K10135 SCOTIN; scotin
K10136 PERP; TP53 apoptosis effector
K10137 ZMAT3; zinc finger, matrin type 3
K04506 SIAH1; E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]
K04506 SIAH1; E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]
K08738 CYC; cytochrome c
K08738 CYC; cytochrome c
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K22745 AIFM2; apoptosis-inducing factor 2
K10138 IGFBP3; insulin-like growth factor-binding protein 3
K05459 IGF1; insulin-like growth factor 1
K03982 SERPINE1; plasminogen activator inhibitor 1
K04596 ADGRB1; adhesion G protein-coupled receptor B1
K06509 KAI1; CD82 antigen
K16857 THBS1; thrombospondin 1
K10139 SERPINB5; serpin B5
K10140 DDB2; DNA damage-binding protein 2
K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
K10141 SESN1_3; sestrin 1/3
K10141 SESN1_3; sestrin 1/3
K20394 SESN2; sestrin 2
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K07207 TSC2; tuberous sclerosis 2
K10142 STEAP3; metalloreductase STEAP3 [EC:1.16.1.-]
K10143 RFWD2; E3 ubiquitin-protein ligase RFWD2 [EC:2.3.2.27]
K10144 RCHY1; RING finger and CHY zinc finger domain-containing protein 1 [EC:2.3.2.27]
K10145 CCNG1; cyclin G1
K10146 CCNG2; cyclin G2
K10147 PPM1D; protein phosphatase 1D [EC:3.1.3.16]
K10148 TP73; tumor protein p73
     04218 Cellular senescence [PATH:aju04218]
 
   09144 Cellular community - eukaryotes
 
   09145 Cellular community - prokaryotes
 
   09142 Cell motility
 
 09150 Organismal Systems
 
 09160 Human Diseases
 
   09161 Cancer: overview
     05200 Pathways in cancer [PATH:aju05200]
       106981192 DCC; netrin receptor DCC isoform X1
       106979326 CASP3; caspase-3 isoform X1
       106975594 CASP9; caspase-9 isoform X1
       106967026 APPL1; DCC-interacting protein 13-alpha
       106972406 CDH1; cadherin-1
       106966666 CTNNB1; catenin beta-1
       106967933 CTNNA1; catenin alpha-1
       106978213 CTNNA2; catenin alpha-2 isoform X1
       106967186 CTNNA3; catenin alpha-3
       106977359 AXIN1; axin-1 isoform X1
       106975307 AXIN2; axin-2
       106973163 APC; adenomatous polyposis coli protein isoform X4
       106983719 APC2; adenomatous polyposis coli protein 2 isoform X1
       106968274 GSK3B; glycogen synthase kinase-3 beta isoform X2
       106984911 TCF7; transcription factor 7 isoform X1
       106978197 TCF7L1; transcription factor 7-like 1
       106974119 TCF7L2; transcription factor 7-like 2 isoform X1
       106983664 LEF1; lymphoid enhancer-binding factor 1 isoform X3
       106981916 BIRC5; baculoviral IAP repeat-containing protein 5 isoform X1
       106976895 MYC; myc proto-oncogene protein
       106971167 CCND1; G1/S-specific cyclin-D1
       106969330 WNT1; proto-oncogene Wnt-1
       106969623 WNT2B; protein Wnt-2b
       106970665 WNT2; protein Wnt-2
       106985206 WNT3A; protein Wnt-3a
       106988834 WNT3; proto-oncogene Wnt-3
       113599491 WNT4; protein Wnt-4
       106967018 WNT5A; protein Wnt-5a isoform X1
       106965408 WNT5B; protein Wnt-5b
       106970073 WNT6; protein Wnt-6
       106978815 WNT7A; protein Wnt-7a isoform X1
       113602684 WNT7B; protein Wnt-7b isoform X1
       106966936 WNT8B; protein Wnt-8b
       106968544 WNT8A; protein Wnt-8a
       106985205 WNT9A; protein Wnt-9a isoform X1
       106988831 WNT9B; protein Wnt-9b
       106970053 WNT10A; protein Wnt-10a
       106969331 WNT10B; protein Wnt-10b
       106976446 WNT11; protein Wnt-11
       106970656 WNT16; protein Wnt-16
       106978285 FZD7; frizzled-7 isoform X1
       106987276 FZD1; frizzled-1
       106974284 FZD2; frizzled-2
       106983024 FZD3; frizzled-3 isoform X1
       106967740 FZD4; frizzled-4 isoform X3
       106967100 FZD5; frizzled-5
       113603657 FZD8; frizzled-8 isoform X1
       106980059 FZD6; frizzled-6
       106986936 FZD10; frizzled-10
       106980711 FZD9; frizzled-9
       106965642 LRP6; low-density lipoprotein receptor-related protein 6 isoform X1
       106971089 LRP5L; LOW QUALITY PROTEIN: low-density lipoprotein receptor-related protein 5-like protein
       106988759 DVL1; segment polarity protein dishevelled homolog DVL-1 isoform X1
       106983787 DVL3; segment polarity protein dishevelled homolog DVL-3 isoform X1
       106972415 DVL2; segment polarity protein dishevelled homolog DVL-2 isoform X1
       113600380 proto-oncogene FRAT1-like
       106978029 F2; prothrombin
       106983558 AGT; angiotensinogen
       113593493 F2RL3; proteinase-activated receptor 4 isoform X1
       106971772 LPAR1; lysophosphatidic acid receptor 1
       106969061 LPAR2; lysophosphatidic acid receptor 2
       106973342 LPAR3; lysophosphatidic acid receptor 3 isoform X1
       106987200 LPAR4; lysophosphatidic acid receptor 4
       106965444 LPAR5; lysophosphatidic acid receptor 5
       106971998 LPAR6; lysophosphatidic acid receptor 6
       106975222 AGTR1; type-1 angiotensin II receptor
       106984497 GNA12; guanine nucleotide-binding protein subunit alpha-12 isoform X1
       106975340 GNA13; guanine nucleotide-binding protein subunit alpha-13
       106974771 ARHGEF12; rho guanine nucleotide exchange factor 12 isoform X1
       106988851 ARHGEF11; rho guanine nucleotide exchange factor 11 isoform X1
       106987699 ARHGEF1; rho guanine nucleotide exchange factor 1 isoform X1
       106982172 PLEKHG5; pleckstrin homology domain-containing family G member 5 isoform X1
       106979239 RHOA; transforming protein RhoA
       106970030 ROCK1; rho-associated protein kinase 1 isoform X1
       106977263 ROCK2; rho-associated protein kinase 2 isoform X1
       106972104 CXCL12; stromal cell-derived factor 1 isoform X1
       106969444 CXCR4; C-X-C chemokine receptor type 4
       106977809 GNAI3; guanine nucleotide-binding protein G(k) subunit alpha
       106982494 GNAI1; guanine nucleotide-binding protein G(i) subunit alpha-1
       106979196 GNAI2; guanine nucleotide-binding protein G(i) subunit alpha-2
       113596587 PTGER1; prostaglandin E2 receptor EP1 subtype isoform X1
       106981938 PTGER2; prostaglandin E2 receptor EP2 subtype
       106982692 PTGER3; prostaglandin E2 receptor EP3 subtype isoform X1
       106970912 PTGER4; prostaglandin E2 receptor EP4 subtype
       106969942 guanine nucleotide-binding protein G(s) subunit alpha
       106969924 neuroendocrine secretory protein 55
       106968223 ADCY1; adenylate cyclase type 1
       106971248 ADCY2; adenylate cyclase type 2 isoform X1
       106989109 ADCY3; adenylate cyclase type 3 isoform X1
       106987869 ADCY4; adenylate cyclase type 4 isoform X1
       106984082 ADCY5; adenylate cyclase type 5 isoform X1
       106969297 ADCY6; adenylate cyclase type 6 isoform X1
       106985835 ADCY7; adenylate cyclase type 7 isoform X1
       106976879 ADCY8; adenylate cyclase type 8 isoform X1
       106978803 ADCY9; adenylate cyclase type 9
       106973352 PRKACB; cAMP-dependent protein kinase catalytic subunit beta isoform X1
       106985791 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X1
       106984654 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
       106987417 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
       106965344 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
       106973885 GNB4; guanine nucleotide-binding protein subunit beta-4
       106967264 GNB5; guanine nucleotide-binding protein subunit beta-5 isoform X1
       106981966 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
       106981725 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
       106982557 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 isoform X1
       106970626 LOW QUALITY PROTEIN: guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
       106973348 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
       106989697 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
       113593434 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 isoform X1
       106977202 LOW QUALITY PROTEIN: guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
       113592841 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
       106969997 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
       106985197 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
       113596552 GNG14; putative guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-14
       106977369 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
       106969996 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
       106985188 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 isoform X1
       106972327 COL4A4; collagen alpha-4(IV) chain isoform X1
       106967336 COL4A6; collagen alpha-6(IV) chain isoform X1
       106967337 COL4A5; collagen alpha-5(IV) chain isoform X1
       106986354 COL4A2; collagen alpha-2(IV) chain
       106986355 COL4A1; collagen alpha-1(IV) chain
       106972295 COL4A3; collagen alpha-3(IV) chain isoform X1
       106984540 LAMA1; laminin subunit alpha-1
       106975487 LAMA2; laminin subunit alpha-2 isoform X1
       106969907 LAMA5; laminin subunit alpha-5
       106978465 LAMA3; laminin subunit alpha-3 isoform X1
       106968914 LAMA4; laminin subunit alpha-4 isoform X1
       106980652 LAMB1; laminin subunit beta-1
       106979235 LAMB2; laminin subunit beta-2 isoform X1
       106981781 LAMB3; laminin subunit beta-3
       106980651 LAMB4; laminin subunit beta-4
       106966784 LAMC1; laminin subunit gamma-1
       106975912 LAMC2; laminin subunit gamma-2
       106985338 LAMC3; laminin subunit gamma-3
       106970125 FN1; fibronectin isoform X1
       106976293 ITGA2; integrin alpha-2
       106974321 ITGA2B; integrin alpha-IIb
       106985164 ITGA3; integrin alpha-3 isoform X1
       106987915 ITGA6; integrin alpha-6 isoform X1
       106976526 ITGAV; integrin alpha-V
       106967340 ITGB1; integrin beta-1 isoform X1
       106984404 PTK2; focal adhesion kinase 1 isoform X1
       106984896 PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1
       106984265 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
       106973880 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
       106976917 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1
       106973297 PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma
       106969150 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
       106980972 PTEN; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X3
       106966563 NKX3-1; homeobox protein Nkx-3.1
       106979622 AKT2; RAC-beta serine/threonine-protein kinase isoform X1
       106975558 AKT3; RAC-gamma serine/threonine-protein kinase isoform X2
       106985046 AKT1; RAC-alpha serine/threonine-protein kinase isoform X1
       106966935 CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X3
       106990012 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1
       106988817 IKBKG; NF-kappa-B essential modulator isoform X1
       106965509 NFKBIA; NF-kappa-B inhibitor alpha
       106984704 NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1
       106966950 NFKB2; nuclear factor NF-kappa-B p100 subunit
       106971136 RELA; transcription factor p65
       106967086 PTGS2; prostaglandin G/H synthase 2
       106984382 NOS2; LOW QUALITY PROTEIN: nitric oxide synthase, inducible
       106985187 BCL2; apoptosis regulator Bcl-2
       106976507 baculoviral IAP repeat-containing protein 3-like
       106976508 BIRC2; baculoviral IAP repeat-containing protein 2
       106972832 XIAP; E3 ubiquitin-protein ligase XIAP
       106973711 BIRC7; baculoviral IAP repeat-containing protein 7
       106986010 BCL2L1; bcl-2-like protein 1
       106986638 TRAF1; TNF receptor-associated factor 1 isoform X1
       106989490 TRAF2; TNF receptor-associated factor 2 isoform X1
       106975974 TRAF3; TNF receptor-associated factor 3 isoform X1
       106983231 TRAF4; TNF receptor-associated factor 4
       106966776 TRAF5; TNF receptor-associated factor 5 isoform X1
       106976941 TRAF6; TNF receptor-associated factor 6
       106984907 MTOR; serine/threonine-protein kinase mTOR isoform X1
       106972702 RPS6KB1; ribosomal protein S6 kinase beta-1 isoform X1
       106971103 RPS6KB2; ribosomal protein S6 kinase beta-2 isoform X1
       106981699 BAD; bcl2-associated agonist of cell death
       106972644 FOXO1; forkhead box protein O1
       106966348 MDM2; E3 ubiquitin-protein ligase Mdm2 isoform X3
       106972437 TP53; cellular tumor antigen p53
       106965649 CDKN1B; cyclin-dependent kinase inhibitor 1B
       106972797 CDKN1A; cyclin-dependent kinase inhibitor 1
       106979667 BCR; breakpoint cluster region protein isoform X1
       106985340 ABL1; tyrosine-protein kinase ABL1
       106989988 CRKL; crk-like protein
       106983188 CRK; adapter molecule crk isoform X1
       106983886 CBL; E3 ubiquitin-protein ligase CBL isoform X1
       106972566 STAT5A; signal transducer and activator of transcription 5A isoform X1
       106972565 signal transducer and activator of transcription 5B isoform X1
       106972749 PIM1; serine/threonine-protein kinase pim-1
       106989008 PIM2; serine/threonine-protein kinase pim-2
       106968026 kininogen-2 isoform X1
       106974187 EDN1; endothelin-1
       106972193 BDKRB2; B2 bradykinin receptor isoform X4
       106983346 EDNRA; endothelin-1 receptor
       106965751 EDNRB; endothelin receptor type B
       106975317 guanine nucleotide-binding protein G(q) subunit alpha isoform X1
       106982140 GNA11; guanine nucleotide-binding protein subunit alpha-11
       106976431 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1
       106976432 PLCB1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X1
       106981698 PLCB3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 isoform X1
       106968579 PLCB2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X1
       106975306 PRKCA; protein kinase C alpha type isoform X1
       106970449 PRKCB; protein kinase C beta type isoform X1
       106980855 PRKCG; protein kinase C gamma type
       106977102 IL2; interleukin-2
       113604567 IL3; interleukin-3
       106970698 IL4; interleukin-4
       106970700 IL5; interleukin-5
       106982277 IL6; interleukin-6 isoform X1
       106984935 IL7; interleukin-7 isoform X1
       106969467 IL12A; interleukin-12 subunit alpha isoform X1
       106967679 IL12B; interleukin-12 subunit beta isoform X2
       106970699 IL13; interleukin-13
       106976203 IL15; interleukin-15
       106986881 IL23A; interleukin-23 subunit alpha
       106987441 EPO; LOW QUALITY PROTEIN: erythropoietin
       106971015 interferon alpha-like
       106971043 interferon alpha-2-like
       106971134 interferon alpha
       106989747 interferon alpha-like
       113593636 interferon alpha-like
       106966359 IFNG; interferon gamma
       106982335 IL2RA; interleukin-2 receptor subunit alpha isoform X1
       106981084 IL2RB; LOW QUALITY PROTEIN: interleukin-2 receptor subunit beta
       106982399 IL2RG; cytokine receptor common subunit gamma
       113597168 IL3RA; LOW QUALITY PROTEIN: interleukin-3 receptor subunit alpha
       106966182 IL4R; interleukin-4 receptor subunit alpha
       106981032 CSF2RB; cytokine receptor common subunit beta
       106969534 IL5RA; interleukin-5 receptor subunit alpha isoform X1
       106987238 IL6R; interleukin-6 receptor subunit alpha isoform X1
       106975253 IL6ST; interleukin-6 receptor subunit beta isoform X1
       106979009 IL7R; interleukin-7 receptor subunit alpha
       106969152 IL12RB1; interleukin-12 receptor subunit beta-1 isoform X1
       106985194 IL12RB2; interleukin-12 receptor subunit beta-2 isoform X1
       106986087 IL13RA1; interleukin-13 receptor subunit alpha-1
       106982336 IL15RA; interleukin-15 receptor subunit alpha isoform X1
       106985193 IL23R; interleukin-23 receptor
       106983947 EPOR; erythropoietin receptor isoform X1
       106966457 IFNAR1; interferon alpha/beta receptor 1
       106966459 IFNAR2; interferon alpha/beta receptor 2 isoform X1
       106985768 IFNGR1; interferon gamma receptor 1
       106966456 IFNGR2; interferon gamma receptor 2
       106970840 EML4; echinoderm microtubule-associated protein-like 4 isoform X1
       106967924 ALK; ALK tyrosine kinase receptor isoform X1
       106985820 RASGRP1; RAS guanyl-releasing protein 1
       106981708 RASGRP2; RAS guanyl-releasing protein 2 isoform X1
       106967894 RASGRP3; ras guanyl-releasing protein 3 isoform X1
       106980248 RASGRP4; RAS guanyl-releasing protein 4 isoform X1
       106983739 JAK1; tyrosine-protein kinase JAK1 isoform X1
       106968145 JAK2; tyrosine-protein kinase JAK2 isoform X1
       106969157 JAK3; tyrosine-protein kinase JAK3
       106972608 STAT3; signal transducer and activator of transcription 3 isoform X1
       106979712 STAT1; signal transducer and activator of transcription 1-alpha/beta
       106986878 STAT2; LOW QUALITY PROTEIN: signal transducer and activator of transcription 2
       106979739 STAT4; signal transducer and activator of transcription 4 isoform X1
       106975851 STAT6; signal transducer and activator of transcription 6 isoform X1
       106974016 VEGFA; vascular endothelial growth factor A
       113597217 VEGFB; vascular endothelial growth factor B isoform X1
       106974417 PGF; placenta growth factor isoform X2
       106974232 VEGFD; vascular endothelial growth factor D
       106976756 VEGFC; vascular endothelial growth factor C
       106967765 TGFA; protransforming growth factor alpha isoform X1
       106983657 EGF; pro-epidermal growth factor isoform X1
       106976977 EGFR; epidermal growth factor receptor
       106980462 ERBB2; receptor tyrosine-protein kinase erbB-2 isoform X1
       106966514 PDGFA; platelet-derived growth factor subunit A isoform X1
       106981002 PDGFB; platelet-derived growth factor subunit B isoform X1
       106983998 PDGFRA; platelet-derived growth factor receptor alpha
       106985388 PDGFRB; platelet-derived growth factor receptor beta isoform X1
       106971906 IGF1; insulin-like growth factor I isoform X1
       113595529 IGF2; insulin-like growth factor II isoform X1
       106975144 IGF1R; insulin-like growth factor 1 receptor isoform X1
       106976559 KITLG; kit ligand isoform X2
       106983989 KIT; mast/stem cell growth factor receptor Kit isoform X1
       106988675 FLT3LG; fms-related tyrosine kinase 3 ligand isoform X1
       106985565 FLT3; receptor-type tyrosine-protein kinase FLT3
       106975661 HGF; hepatocyte growth factor isoform X1
       106970667 MET; hepatocyte growth factor receptor
       106967134 FGF1; fibroblast growth factor 1 isoform X1
       106977090 FGF2; fibroblast growth factor 2 isoform X1
       106966945 FGF8; fibroblast growth factor 8 isoform X1
       106967112 FGF10; fibroblast growth factor 10
       106967225 FGF7; fibroblast growth factor 7 isoform X1
       106965488 FGF6; fibroblast growth factor 6
       106972632 FGF20; fibroblast growth factor 20
       106976900 FGF5; fibroblast growth factor 5 isoform X1
       106988440 FGF16; fibroblast growth factor 16
       106979814 FGF9; fibroblast growth factor 9
       106981101 FGF17; fibroblast growth factor 17 isoform X1
       106973440 FGF18; fibroblast growth factor 18
       113595410 FGF3; fibroblast growth factor 3
       113596382 FGF22; fibroblast growth factor 22
       113595513 FGF4; fibroblast growth factor 4
       106988712 FGF21; fibroblast growth factor 21
       106965456 FGF23; fibroblast growth factor 23
       106978376 FGFR1; fibroblast growth factor receptor 1 isoform X1
       106969379 FGFR2; fibroblast growth factor receptor 2 isoform X1
       106978850 FGFR3; fibroblast growth factor receptor 3 isoform X1
       106975403 FGFR4; fibroblast growth factor receptor 4 isoform X1
       106987795 GRB2; growth factor receptor-bound protein 2
       106978987 SOS1; son of sevenless homolog 1 isoform X1
       106989073 SOS2; son of sevenless homolog 2 isoform X1
       106987957 HRAS; GTPase HRas isoform X1
       106968778 KRAS; GTPase KRas isoform X1
       106969596 NRAS; GTPase NRas
       106972677 ARAF; serine/threonine-protein kinase A-Raf
       106970441 BRAF; serine/threonine-protein kinase B-raf isoform X1
       106977129 RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X1
       106980282 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 isoform X2
       106975474 MAP2K2; dual specificity mitogen-activated protein kinase kinase 2 isoform X1
       106969232 MAPK3; mitogen-activated protein kinase 3 isoform X2
       106990008 MAPK1; mitogen-activated protein kinase 1
       106974986 JUN; transcription factor AP-1
       106974355 FOS; proto-oncogene c-Fos
       106984369 ETS1; protein C-ets-1 isoform X1
       106976487 interstitial collagenase
       106976478 LOW QUALITY PROTEIN: interstitial collagenase-like
       106973291 MMP2; 72 kDa type IV collagenase
       106969010 MMP9; matrix metalloproteinase-9
       106982166 CXCL8; interleukin-8
       106981787 interleukin-8-like
       106975871 CDK4; cyclin-dependent kinase 4 isoform X1
       106987903 RPS6KA5; ribosomal protein S6 kinase alpha-5 isoform X1
       106972131 RET; proto-oncogene tyrosine-protein kinase receptor Ret
       106989899 CCDC6; coiled-coil domain-containing protein 6
       106989445 NCOA4; nuclear receptor coactivator 4 isoform X1
       106988854 NTRK1; high affinity nerve growth factor receptor
       106987255 TPM3; tropomyosin alpha-3 chain isoform X3
       106967082 TPR; nucleoprotein TPR isoform X1
       106969421 TFG; protein TFG isoform X1
       106979265 RASSF1; ras association domain-containing protein 1 isoform X1
       106972884 RASSF5; ras association domain-containing protein 5 isoform X1
       106968996 STK4; serine/threonine-protein kinase 4
       106987289 DAPK2; death-associated protein kinase 2 isoform X1
       106971447 DAPK1; death-associated protein kinase 1 isoform X1
       113596415 DAPK3; death-associated protein kinase 3
       106974495 PLCG1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1
       106984018 PLCG2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
       106972898 ELK1; ETS domain-containing protein Elk-1
       106980445 CALML4; LOW QUALITY PROTEIN: calmodulin-like protein 4
       106987911 CALM1; calmodulin-1
       106977221 CALM2; calmodulin-2
       106984637 CALML6; calmodulin-like protein 6 isoform X1
       106973635 CALM3; calmodulin-3 isoform X1
       106988136 calmodulin-like protein 3
       106988135 calmodulin-like
       106977318 CAMK2D; calcium/calmodulin-dependent protein kinase type II subunit delta isoform X5
       106968235 CAMK2B; calcium/calmodulin-dependent protein kinase type II subunit beta
       106970983 CAMK2G; calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X1
       106985400 CAMK2A; calcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1
       106985322 RALGDS; ral guanine nucleotide dissociation stimulator isoform X1
       106989551 ral guanine nucleotide dissociation stimulator-like isoform X1
       113597310 ral guanine nucleotide dissociation stimulator-like
       106974372 RALA; ras-related protein Ral-A
       106966391 RALB; ras-related protein Ral-B
       106965553 RALBP1; ralA-binding protein 1
       106977652 CDC42; cell division control protein 42 homolog isoform X1
       106982604 RAC1; ras-related C3 botulinum toxin substrate 1 isoform X1
       106981077 RAC2; ras-related C3 botulinum toxin substrate 2 isoform X1
       106986311 RAC3; ras-related C3 botulinum toxin substrate 3 isoform X1
       106990052 PLD1; phospholipase D1 isoform X1
       106972398 PLD2; phospholipase D2
       106969894 MAPK9; mitogen-activated protein kinase 9 isoform X1
       106970668 MAPK10; mitogen-activated protein kinase 10 isoform X2
       106989581 MAPK8; mitogen-activated protein kinase 8 isoform X1
       106978160 PAX8; paired box protein Pax-8 isoform X1
       106977134 PPARG; peroxisome proliferator-activated receptor gamma isoform X1
       106988254 RXRA; retinoic acid receptor RXR-alpha isoform X1
       106976118 RXRB; retinoic acid receptor RXR-beta isoform X1
       106965571 RXRG; retinoic acid receptor RXR-gamma isoform X2
       106988245 RARB; retinoic acid receptor beta isoform X1
       106976266 ESR1; estrogen receptor isoform X1
       106971325 ESR2; estrogen receptor beta
       106989110 NCOA1; nuclear receptor coactivator 1 isoform X1
       106968987 NCOA3; nuclear receptor coactivator 3
       106983094 SP1; transcription factor Sp1
       106972816 PPARD; peroxisome proliferator-activated receptor delta isoform X1
       106972560 JUP; junction plakoglobin
       106980593 ZBTB16; zinc finger and BTB domain-containing protein 16
       106980526 RARA; retinoic acid receptor alpha isoform X3
       106977098 CCNA2; cyclin-A2
       106973846 CCNA1; cyclin-A1 isoform X1
       106979429 PML; protein PML isoform X1
       106966472 RUNX1; runt-related transcription factor 1 isoform X1
       106974898 RUNX1T1; protein CBFA2T1 isoform X3
       106978062 SPI1; transcription factor PU.1 isoform X3
       106975747 CEBPA; CCAAT/enhancer-binding protein alpha
       106982042 granulocyte-macrophage colony-stimulating factor receptor subunit alpha-like isoform X1
       106982043 granulocyte-macrophage colony-stimulating factor receptor subunit alpha-like isoform X1
       106973256 CSF3R; granulocyte colony-stimulating factor receptor isoform X1
       106985394 CSF1R; macrophage colony-stimulating factor 1 receptor
       106986386 cyclin-dependent kinase inhibitor 2A-like
       106974609 E2F1; transcription factor E2F1
       106977597 E2F2; transcription factor E2F2
       106987605 E2F3; transcription factor E2F3
       106971305 MAX; protein max isoform X1
       106975602 ZBTB17; zinc finger and BTB domain-containing protein 17 isoform X1
       106986385 CDKN2B; cyclin-dependent kinase 4 inhibitor B
       106969949 CDK6; cyclin-dependent kinase 6
       106965383 CCND2; G1/S-specific cyclin-D2
       106974052 CCND3; G1/S-specific cyclin-D3 isoform X2
       106988394 CKS1B; cyclin-dependent kinases regulatory subunit 1
       106976137 CKS2; cyclin-dependent kinases regulatory subunit 2
       106984903 SKP1; S-phase kinase-associated protein 1
       106981418 CUL1; cullin-1 isoform X1
       113602716 RBX1; E3 ubiquitin-protein ligase RBX1
       106979642 SKP2; S-phase kinase-associated protein 2 isoform X1
       106986916 CDK2; cyclin-dependent kinase 2 isoform X1
       106974883 CCNE2; G1/S-specific cyclin-E2 isoform X1
       106975766 CCNE1; G1/S-specific cyclin-E1
       106971960 RB1; retinoblastoma-associated protein isoform X1
       106989693 GADD45B; growth arrest and DNA damage-inducible protein GADD45 beta
       106985200 GADD45A; growth arrest and DNA damage-inducible protein GADD45 alpha
       113594268 GADD45G; growth arrest and DNA damage-inducible protein GADD45 gamma
       106988699 BAX; apoptosis regulator BAX isoform X1
       106976101 BAK1; bcl-2 homologous antagonist/killer
       106978021 DDB2; DNA damage-binding protein 2 isoform X1
       106974834 POLK; DNA polymerase kappa isoform X1
       106985112 TERT; telomerase reverse transcriptase isoform X1
       106985486 MITF; microphthalmia-associated transcription factor isoform X7
       106987682 TGFB1; transforming growth factor beta-1 proprotein isoform X1
       106979500 TGFB2; transforming growth factor beta-2 proprotein isoform X1
       106974351 TGFB3; transforming growth factor beta-3 proprotein isoform X1
       106972043 TGFBR1; TGF-beta receptor type-1 isoform X1
       106984570 TGFBR2; TGF-beta receptor type-2
       106972947 SMAD2; mothers against decapentaplegic homolog 2 isoform X1
       106980367 SMAD3; mothers against decapentaplegic homolog 3 isoform X2
       106974966 SMAD4; mothers against decapentaplegic homolog 4 isoform X1
       106990036 MECOM; MDS1 and EVI1 complex locus protein isoform X1
       106978849 CTBP1; C-terminal-binding protein 1 isoform X1
       106971722 CTBP2; C-terminal-binding protein 2 isoform X1
       106968918 HDAC2; histone deacetylase 2 isoform X1
       106982428 HDAC1; histone deacetylase 1 isoform X2
       106982621 MLH1; DNA mismatch repair protein Mlh1 isoform X1
       106977220 MSH2; DNA mismatch repair protein Msh2
       106972137 MSH3; DNA mismatch repair protein Msh3 isoform X1
       106977218 MSH6; DNA mismatch repair protein Msh6 isoform X1
       106973859 BRCA2; breast cancer type 2 susceptibility protein isoform X2
       106968536 RAD51; DNA repair protein RAD51 homolog 1
       106979842 FASLG; tumor necrosis factor ligand superfamily member 6
       106980953 FAS; tumor necrosis factor receptor superfamily member 6 isoform X1
       106982870 FADD; FAS-associated death domain protein
       106987995 CASP8; caspase-8
       106968455 BID; BH3-interacting domain death agonist
       106978896 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
       106973568 BBC3; bcl-2-binding component 3
       106976034 BCL2L11; bcl-2-like protein 11 isoform X1
       106988781 cytochrome c
       106982840 cytochrome c
       106986613 cytochrome c-like
       106973746 APAF1; apoptotic protease-activating factor 1 isoform X1
       106974123 CASP7; caspase-7 isoform X1
       106980317 KEAP1; kelch-like ECH-associated protein 1
       106988161 NFE2L2; nuclear factor erythroid 2-related factor 2 isoform X1
       106981079 HMOX1; heme oxygenase 1
       106972182 NQO1; NAD(P)H dehydrogenase [quinone] 1 isoform X1
       106966916 GSTO2; glutathione S-transferase omega-2 isoform X1
       106966917 GSTO1; glutathione S-transferase omega-1
       106977846 glutathione S-transferase Mu 3
       106977852 glutathione S-transferase Mu 4
       106965575 MGST3; microsomal glutathione S-transferase 3
       106965679 MGST1; microsomal glutathione S-transferase 1
       106973067 glutathione S-transferase A2
       106973068 GSTA4; glutathione S-transferase A4
       106973069 glutathione S-transferase A2-like
       106979662 LOW QUALITY PROTEIN: glutathione S-transferase theta-2B-like
       106979690 glutathione S-transferase theta-1 isoform X1
       106979693 glutathione S-transferase theta-1-like
       106976197 MGST2; microsomal glutathione S-transferase 2
       106979691 glutathione S-transferase theta-4
       113592407 glutathione S-transferase theta-3-like isoform X1
       106973070 glutathione S-transferase A4-like isoform X1
       106971176 glutathione S-transferase P
       106971915 TXNRD1; thioredoxin reductase 1, cytoplasmic isoform X1
       106985737 TXNRD3; thioredoxin reductase 3
       106983612 TXNRD2; thioredoxin reductase 2, mitochondrial isoform X1
       106972341 VHL; von Hippel-Lindau disease tumor suppressor isoform X1
       106968366 ELOC; elongin-C isoform X1
       106987182 elongin-C-like isoform X2
       113594935 ELOB; elongin-B
       106977252 uncharacterized protein LOC106977252
       106967342 CUL2; cullin-2
       106976258 EGLN3; egl nine homolog 3
       106979627 EGLN2; egl nine homolog 2 isoform X1
       106981639 EGLN1; egl nine homolog 1 isoform X1
       106975565 FH; fumarate hydratase, mitochondrial
       106971299 HIF1A; hypoxia-inducible factor 1-alpha
       106977230 EPAS1; endothelial PAS domain-containing protein 1 isoform X1
       106979844 ARNT; aryl hydrocarbon receptor nuclear translocator isoform X1
       106988477 ARNT2; aryl hydrocarbon receptor nuclear translocator 2 isoform X1
       106979918 EP300; histone acetyltransferase p300
       106978741 CREBBP; CREB-binding protein isoform X1
       106970163 SLC2A1; solute carrier family 2, facilitated glucose transporter member 1
       106983335 JAG1; protein jagged-1
       106985950 JAG2; protein jagged-2 isoform X1
       106979590 DLL3; delta-like protein 3
       106978660 DLL1; delta-like protein 1
       106968571 DLL4; delta-like protein 4
       106989563 NOTCH1; neurogenic locus notch homolog protein 1
       106978507 NOTCH2; neurogenic locus notch homolog protein 2 isoform X1
       106982902 NOTCH3; neurogenic locus notch homolog protein 3
       106983489 NOTCH4; neurogenic locus notch homolog protein 4 isoform X1
       106976345 HES1; transcription factor HES-1
       113599588 HES5; transcription factor HES-5
       106970871 HEY1; hairy/enhancer-of-split related with YRPW motif protein 1 isoform X1
       106986140 HEY2; hairy/enhancer-of-split related with YRPW motif protein 2 isoform X1
       106988989 HEYL; hairy/enhancer-of-split related with YRPW motif-like protein
       106970218 FLT4; vascular endothelial growth factor receptor 3 isoform X1
       113596760 SHH; sonic hedgehog protein
       106971452 PTCH1; protein patched homolog 1 isoform X1
       106973896 SMO; smoothened homolog
       106965925 KIF7; kinesin-like protein KIF7 isoform X1
       106966951 SUFU; suppressor of fused homolog isoform X1
       106975858 GLI1; zinc finger protein GLI1 isoform X1
       106966424 GLI2; zinc finger protein GLI2
       106977751 GLI3; transcriptional activator GLI3 isoform X1
       106976426 BMP2; bone morphogenetic protein 2
       106983046 BMP4; bone morphogenetic protein 4 isoform X1
       106983467 HHIP; hedgehog-interacting protein
       106970235 PTCH2; protein patched homolog 2 isoform X1
       106986605 AR; androgen receptor isoform X1
       106975969 HSP90AA1; heat shock protein HSP 90-alpha
       106974012 HSP90AB1; heat shock protein HSP 90-beta
       106971910 HSP90B1; endoplasmin
K06765 DCC; deleted in colorectal carcinoma
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K08733 APPL1; DCC-interacting protein 13 alpha
K05689 CDH1; cadherin 1, type 1, E-cadherin
K02105 CTNNB1; catenin beta 1
K05691 CTNNA; catenin alpha
K05691 CTNNA; catenin alpha
K05691 CTNNA; catenin alpha
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02085 APC; adenomatosis polyposis coli protein
K02085 APC; adenomatosis polyposis coli protein
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K08731 BIRC5; baculoviral IAP repeat-containing protein 5
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; G1/S-specific cyclin-D1
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7; frizzled 1/7
K02432 FZD1_7; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4; frizzled 4
K02375 FZD5_8; frizzled 5/8
K02375 FZD5_8; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10; frizzled 9/10
K02842 FZD9_10; frizzled 9/10
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K03069 FRAT1; frequently rearranged in advanced T-cell lymphomas 1
K01313 F2; coagulation factor II (thrombin) [EC:3.4.21.5]
K09821 AGT; angiotensinogen
K04236 F2RL3; coagulation factor II (thrombin) receptor-like 3
K04289 LPAR1; lysophosphatidic acid receptor 1
K04291 LPAR2; lysophosphatidic acid receptor 2
K04294 LPAR3; lysophosphatidic acid receptor 3
K04275 LPAR4; lysophosphatidic acid receptor 4
K08390 LPAR5; lysophosphatidic acid receptor 5
K04273 LPAR6; lysophosphatidic acid receptor 6
K04166 AGTR1; angiotensin II receptor type 1
K04346 GNA12; guanine nucleotide-binding protein subunit alpha-12
K04639 GNA13; guanine nucleotide-binding protein subunit alpha-13
K07532 ARHGEF12; Rho guanine nucleotide exchange factor 12
K12331 ARHGEF11; Rho guanine nucleotide exchange factor 11
K12330 ARHGEF1; Rho guanine nucleotide exchange factor 1
K19464 PLEKHG5; pleckstrin homology domain-containing family G member 5
K04513 RHOA; Ras homolog gene family, member A
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K10031 CXCL12; C-X-C motif chemokine 12
K04189 CXCR4; C-X-C chemokine receptor type 4
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04258 PTGER1; prostaglandin E receptor 1
K04259 PTGER2; prostaglandin E receptor 2
K04260 PTGER3; prostaglandin E receptor 3
K04261 PTGER4; prostaglandin E receptor 4
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K05637 LAMA1_2; laminin, alpha 1/2
K05637 LAMA1_2; laminin, alpha 1/2
K06240 LAMA3_5; laminin, alpha 3/5
K06240 LAMA3_5; laminin, alpha 3/5
K06241 LAMA4; laminin, alpha 4
K05636 LAMB1; laminin, beta 1
K06243 LAMB2; laminin, beta 2
K06244 LAMB3; laminin, beta 3
K06245 LAMB4; laminin, beta 4
K05635 LAMC1; laminin, gamma 1
K06246 LAMC2; laminin, gamma 2
K06247 LAMC3; laminin, gamma 3
K05717 FN1; fibronectin 1
K06481 ITGA2; integrin alpha 2
K06476 ITGA2B; integrin alpha 2B
K06482 ITGA3; integrin alpha 3
K06485 ITGA6; integrin alpha 6
K06487 ITGAV; integrin alpha V
K05719 ITGB1; integrin beta 1
K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K09348 NKX3-1; homeobox protein Nkx-3.1
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04469 NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
K04735 RELA; transcription factor p65
K11987 PTGS2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
K02161 BCL2; apoptosis regulator Bcl-2
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04725 XIAP; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K16061 BIRC7_8; baculoviral IAP repeat-containing protein 7/8
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K03172 TRAF1; TNF receptor-associated factor 1
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K03174 TRAF3; TNF receptor-associated factor 3
K09848 TRAF4; TNF receptor-associated factor 4
K09849 TRAF5; TNF receptor-associated factor 5
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K07201 FOXO1; forkhead box protein O1
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53; tumor protein p53
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K08878 BCR1; breakpoint cluster region protein [EC:2.7.11.1]
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K04438 CRK; C-crk adapter molecule crk
K04438 CRK; C-crk adapter molecule crk
K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K04702 PIM1; proto-oncogene serine/threonine-protein kinase Pim-1 [EC:2.7.11.1]
K08806 PIM2; proto-oncogene serine/threonine-protein kinase Pim-2 [EC:2.7.11.1]
K03898 KNG; kininogen
K16366 EDN1; endothelin-1
K03916 BDKRB2; bradykinin receptor B2
K04197 EDNRA; endothelin receptor type A
K04198 EDNRB; endothelin receptor type B
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K05429 IL2; interleukin 2
K04736 IL3; interleukin 3
K05430 IL4; interleukin 4
K05428 IL5; interleukin 5
K05405 IL6; interleukin 6
K05431 IL7; interleukin 7
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05435 IL13; interleukin 13
K05433 IL15; interleukin 15
K05426 IL23A; interleukin 23 subunit alpha
K05437 EPO; erythropoietin
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K04687 IFNG; interferon gamma
K05068 IL2RA; interleukin 2 receptor alpha
K05069 IL2RB; interleukin 2 receptor beta
K05070 IL2RG; interleukin 2 receptor gamma
K04737 IL3RA; interleukin 3 receptor alpha
K05071 IL4R; interleukin 4 receptor
K04738 CSF2RB; cytokine receptor common subunit beta
K05067 IL5RA. CD125; interleukin 5 receptor alpha
K05055 IL6R; interleukin 6 receptor
K05060 IL6ST; interleukin 6 signal transducer
K05072 IL7R; interleukin 7 receptor
K05063 IL12RB1; interleukin 12 receptor beta-1
K05064 IL12RB2; interleukin 12 receptor beta-2
K05076 IL13RA1; interleukin 13 receptor alpha-1
K05074 IL15RA; interleukin 15 receptor alpha
K05065 IL23R; interleukin 23 receptor
K05079 EPOR; erythropoietin receptor
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K05132 IFNGR1; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K15420 EML4; echinoderm microtubule-associated protein-like 4
K05119 ALK; anaplastic lymphoma kinase [EC:2.7.10.1]
K04350 RASGRP1; RAS guanyl-releasing protein 1
K12361 RASGRP2; RAS guanyl-releasing protein 2
K12362 RASGRP3; RAS guanyl-releasing protein 3
K12363 RASGRP4; RAS guanyl-releasing protein 4
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K11222 STAT4; signal transducer and activator of transcription 4
K11225 STAT6; signal transducer and activator of transcription 6
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K16859 PGF; placenta growth factor
K05449 VEGFC_D; vascular endothelial growth factor C/D
K05449 VEGFC_D; vascular endothelial growth factor C/D
K08774 TGFA; transforming growth factor, alpha
K04357 EGF; epidermal growth factor
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K04363 PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05459 IGF1; insulin-like growth factor 1
K13769 IGF2; insulin-like growth factor 2
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K05461 KITLG; KIT ligand
K05091 KIT; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K05454 FLT3LG; fms-related tyrosine kinase 3 ligand
K05092 FLT3; fms-related tyrosine kinase 3 [EC:2.7.10.1]
K05460 HGF; hepatocyte growth factor
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K04362 FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04379 FOS; proto-oncogene protein c-fos
K02678 ETS1; C-ets-1
K01388 MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
K01388 MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
K01398 MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K10030 IL8; interleukin 8
K10030 IL8; interleukin 8
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K04445 RPS6KA5; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
K05126 RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
K09288 CCDC6; coiled-coil domain-containing protein 6
K09289 NCOA4; nuclear receptor coactivator 4
K03176 NTRK1; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K09290 TPM3; tropomyosin 3
K09291 TPR; nucleoprotein TPR
K09292 TFG; protein TFG
K09850 RASSF1; Ras association domain-containing protein 1
K08015 RASSF5; Ras association domain-containing protein 5
K04411 STK4; serine/threonine kinase 4
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K04375 ELK1; ETS domain-containing protein Elk-1
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K07834 RALA; Ras-related protein Ral-A
K07835 RALB; Ras-related protein Ral-B
K08773 RALBP1; RalA-binding protein 1
K04393 CDC42; cell division control protein 42
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K09293 PAX8; paired box protein 8
K08530 NR1C3; peroxisome proliferator-activated receptor gamma
K08524 RXRA; retinoid X receptor alpha
K08525 RXRB; retinoid X receptor beta
K08526 RXRG; retinoid X receptor gamma
K08528 RARB; retinoic acid receptor beta
K08550 ESR1; estrogen receptor alpha
K08551 ESR2; estrogen receptor beta
K09101 NCOA1; nuclear receptor coactivator 1 [EC:2.3.1.48]
K11256 NCOA3; nuclear receptor coactivator 3 [EC:2.3.1.48]
K04684 SP1; transcription factor Sp1
K04504 NR1C2; peroxisome proliferator-activated receptor delta
K10056 JUP; junction plakoglobin
K10055 ZBTB16; zinc finger and BTB domain-containing protein 16
K08527 RARA; retinoic acid receptor alpha
K06627 CCNA; cyclin-A
K06627 CCNA; cyclin-A
K10054 PML; probable transcription factor PML
K08367 RUNX1; runt-related transcription factor 1
K10053 RUNX1T1; CBFA2/RNUX1 translocation partner 1
K09438 SPI1; transcription factor PU.1
K09055 CEBPA; CCAAT/enhancer binding protein (C/EBP), alpha
K05066 CSF2RA; granulocyte-macrophage colony-stimulating factor receptor alpha
K05066 CSF2RA; granulocyte-macrophage colony-stimulating factor receptor alpha
K05061 CSF3R; granulocyte colony-stimulating factor receptor
K05090 CSF1R; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04453 MAX; Max protein
K10500 ZBTB17; zinc finger and BTB domain-containing protein 17
K04685 CDKN2B; cyclin-dependent kinase inhibitor 2B
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K02219 CKS1; cyclin-dependent kinase regulatory subunit CKS1
K02219 CKS1; cyclin-dependent kinase regulatory subunit CKS1
K03094 SKP1; S-phase kinase-associated protein 1
K03347 CUL1; cullin 1
K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
K03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K06618 RB1; retinoblastoma-associated protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]
K09455 MITF; microphthalmia-associated transcription factor
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04462 MECOM; [histone H3]-lysine9 N-methyltransferase (ecotropic virus integration site 1 protein) [EC:2.1.1.367]
K04496 CTBP; C-terminal binding protein
K04496 CTBP; C-terminal binding protein
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K08734 MLH1; DNA mismatch repair protein MLH1
K08735 MSH2; DNA mismatch repair protein MSH2
K08736 MSH3; DNA mismatch repair protein MSH3
K08737 MSH6; DNA mismatch repair protein MSH6
K08775 BRCA2; breast cancer 2 susceptibility protein
K04482 RAD51; DNA repair protein RAD51
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K10131 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
K10132 BBC3; Bcl-2-binding component 3
K16341 BCL2L11; Bcl-2-like protein 11
K08738 CYC; cytochrome c
K08738 CYC; cytochrome c
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04397 CASP7; caspase 7 [EC:3.4.22.60]
K10456 KLHL19; kelch-like protein 19
K05638 NFE2L2; nuclear factor erythroid 2-related factor 2
K00510 HMOX1; heme oxygenase 1 [EC:1.14.14.18]
K00355 NQO1; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K23790 GSTP; glutathione S-transferase P [EC:2.5.1.18]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K03871 VHL; von Hippel-Lindau disease tumor supressor
K03872 ELOC; elongin-C
K03872 ELOC; elongin-C
K03873 ELOB; elongin-B
K03873 ELOB; elongin-B
K03870 CUL2; cullin 2
K09592 EGLN; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K09592 EGLN; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K09592 EGLN; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K09095 HIF2A; hypoxia-inducible factor 2 alpha
K09097 ARNT; aryl hydrocarbon receptor nuclear translocator
K15589 ARNT2; aryl hydrocarbon receptor nuclear translocator 2
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K07299 SLC2A1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
K06052 JAG1; jagged-1
K21635 JAG2; jagged-2
K06051 DLL; delta
K06051 DLL; delta
K06051 DLL; delta
K02599 NOTCH1; Notch 1
K20994 NOTCH2; Notch 2
K20995 NOTCH3; Notch 3
K20996 NOTCH4; Notch 4
K06054 HES1; hairy and enhancer of split 1
K06055 HES5; hairy and enhancer of split 5
K09091 HEY; hairy and enhancer of split related with YRPW motif
K09091 HEY; hairy and enhancer of split related with YRPW motif
K09091 HEY; hairy and enhancer of split related with YRPW motif
K05097 FLT4; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K11988 SHH; sonic hedgehog
K06225 PTCH1; patched 1
K06226 SMO; smoothened
K18806 KIF7; kinesin family member 7
K06229 SUFU; suppressor of fused
K16797 GLI1; zinc finger protein GLI1
K16798 GLI2; zinc finger protein GLI2
K06230 GLI3; zinc finger protein GLI3
K21283 BMP2; bone morphogenetic protein 2
K04662 BMP4; bone morphogenetic protein 4
K06231 HHIP; hedgehog interacting protein
K11101 PTCH2; patched 2
K08557 AR; androgen receptor
K04079 HSP90A; molecular chaperone HtpG
K04079 HSP90A; molecular chaperone HtpG
K09487 HSP90B; heat shock protein 90kDa beta
     05202 Transcriptional misregulation in cancer [PATH:aju05202]
     05206 MicroRNAs in cancer [PATH:aju05206]
     05205 Proteoglycans in cancer [PATH:aju05205]
     05204 Chemical carcinogenesis [PATH:aju05204]
     05203 Viral carcinogenesis [PATH:aju05203]
       106974507 SRC; proto-oncogene tyrosine-protein kinase Src isoform X1
       106987957 HRAS; GTPase HRas isoform X1
       106968778 KRAS; GTPase KRas isoform X1
       106969596 NRAS; GTPase NRas
       106969232 MAPK3; mitogen-activated protein kinase 3 isoform X2
       106990008 MAPK1; mitogen-activated protein kinase 1
       106967098 CREB1; cyclic AMP-responsive element-binding protein 1 isoform X1
       106988085 ATF2; cyclic AMP-dependent transcription factor ATF-2 isoform X1
       106979942 ATF4; cyclic AMP-dependent transcription factor ATF-4
       106981255 CREB3; cyclic AMP-responsive element-binding protein 3
       106970423 CREB3L2; cyclic AMP-responsive element-binding protein 3-like protein 2 isoform X1
       106987262 CREB3L4; cyclic AMP-responsive element-binding protein 3-like protein 4 isoform X1
       106975473 CREB3L3; cyclic AMP-responsive element-binding protein 3-like protein 3 isoform X1
       106978069 CREB3L1; cyclic AMP-responsive element-binding protein 3-like protein 1
       106987665 CREB5; cyclic AMP-responsive element-binding protein 5 isoform X6
       106983500 ATF6B; LOW QUALITY PROTEIN: cyclic AMP-dependent transcription factor ATF-6 beta
       106977885 DDB1; DNA damage-binding protein 1
       106968957 YWHAB; 14-3-3 protein beta/alpha
       106982949 YWHAQ; 14-3-3 protein theta
       106989479 14-3-3 protein theta
       106980045 YWHAZ; 14-3-3 protein zeta/delta
       106983214 YWHAE; 14-3-3 protein epsilon isoform X2
       106983312 YWHAH; 14-3-3 protein eta
       106980702 YWHAG; 14-3-3 protein gamma
       106983739 JAK1; tyrosine-protein kinase JAK1 isoform X1
       106972608 STAT3; signal transducer and activator of transcription 3 isoform X1
       106972566 STAT5A; signal transducer and activator of transcription 5A isoform X1
       106972565 signal transducer and activator of transcription 5B isoform X1
       106979326 CASP3; caspase-3 isoform X1
       106974756 HPN; serine protease hepsin isoform X1
       106984896 PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1
       106984265 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
       106973880 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
       106976917 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1
       106973297 PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma
       106969150 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
       106971136 RELA; transcription factor p65
       106973464 REL; proto-oncogene c-Rel
       106966950 NFKB2; nuclear factor NF-kappa-B p100 subunit
       106984704 NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1
       106972437 TP53; cellular tumor antigen p53
       106974883 CCNE2; G1/S-specific cyclin-E2 isoform X1
       106975766 CCNE1; G1/S-specific cyclin-E1
       106986916 CDK2; cyclin-dependent kinase 2 isoform X1
       106989877 EGR2; E3 SUMO-protein ligase EGR2
       106981096 EGR3; early growth response protein 3 isoform X1
       106990014 VDAC3; voltage-dependent anion-selective channel protein 3 isoform X1
       106965448 LTBR; tumor necrosis factor receptor superfamily member 3
       106972309 SP100; nuclear autoantigen Sp-100 isoform X4
       106978574 HNRNPK; heterogeneous nuclear ribonucleoprotein K isoform X1
       106972797 CDKN1A; cyclin-dependent kinase inhibitor 1
       106984213 DDX3X; ATP-dependent RNA helicase DDX3X isoform X1
       106985057 ATP-dependent RNA helicase DDX3X-like
       106978970 EIF2AK2; interferon-induced, double-stranded RNA-activated protein kinase isoform X1
       106973352 PRKACB; cAMP-dependent protein kinase catalytic subunit beta isoform X1
       106985791 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X1
       106969569 late histone H2B.L4-like
       106988040 histone H2B type 1
       106988062 histone H2B type 1-M
       106988064 histone H2B type 1-K
       106988066 histone H2B type 1
       106988082 histone H2B type 1-A-like
       106974815 histone H2B subacrosomal variant-like
       106989350 histone H2B type 1-A
       106985218 histone H2B type 3-B
       106986679 histone H2B type 1-B
       106982106 histone H2B type 2-F
       106976313 histone H2B type 1-K
       106985210 LOW QUALITY PROTEIN: histone H2B-like
       113597270 histone H2B type 1-like
       113592690 histone H2B-like
       113593971 histone H2B type 1
       113592389 histone H2B type 1
       106988080 histone H2B type 1-K
       106965662 histone H4
       106988031 histone H4
       106988053 histone H4
       106988073 histone H4
       106988075 histone H4
       106988077 histone H4
       106982111 histone H4
       106976315 histone H4
       106976328 histone H4
       106976329 histone H4
       106988032 histone H4
       113593855 histone H4
       106988699 BAX; apoptosis regulator BAX isoform X1
       106987795 GRB2; growth factor receptor-bound protein 2
       106971422 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
       106989884 CDK1; cyclin-dependent kinase 1
       106984326 TBPL2; TATA box-binding protein-like protein 2
       106976865 TBPL1; TATA box-binding protein-like protein 1 isoform X1
       106978655 TBP; TATA-box-binding protein
       106971787 USP7; ubiquitin carboxyl-terminal hydrolase 7 isoform X1
       106966348 MDM2; E3 ubiquitin-protein ligase Mdm2 isoform X3
       106968999 RBPJL; recombining binding protein suppressor of hairless-like protein isoform X1
       106975118 RBPJ; recombining binding protein suppressor of hairless isoform X1
       106974389 SNW1; SNW domain-containing protein 1
       106987482 GTF2H1; general transcription factor IIH subunit 1
       106977079 general transcription factor IIH subunit 2
       106978344 GTF2H3; general transcription factor IIH subunit 3 isoform X1
       106966622 GTF2H4; general transcription factor IIH subunit 4 isoform X1
       106975424 GTF2E1; general transcription factor IIE subunit 1
       106966554 GTF2E2; transcription initiation factor IIE subunit beta isoform X1
       106988446 SND1; staphylococcal nuclease domain-containing protein 1
       106979918 EP300; histone acetyltransferase p300
       106978741 CREBBP; CREB-binding protein isoform X1
       106968045 GTF2B; transcription initiation factor IIB
       106971167 CCND1; G1/S-specific cyclin-D1
       106965383 CCND2; G1/S-specific cyclin-D2
       106974052 CCND3; G1/S-specific cyclin-D3 isoform X2
       106969949 CDK6; cyclin-dependent kinase 6
       106977098 CCNA2; cyclin-A2
       106973846 CCNA1; cyclin-A1 isoform X1
       106979642 SKP2; S-phase kinase-associated protein 2 isoform X1
       106966614 MRPS18B; 28S ribosomal protein S18b, mitochondrial isoform X1
       106986638 TRAF1; TNF receptor-associated factor 1 isoform X1
       106989490 TRAF2; TNF receptor-associated factor 2 isoform X1
       106975974 TRAF3; TNF receptor-associated factor 3 isoform X1
       106966776 TRAF5; TNF receptor-associated factor 5 isoform X1
       106969157 JAK3; tyrosine-protein kinase JAK3
       106982528 LYN; tyrosine-protein kinase Lyn isoform X3
       106976132 SYK; tyrosine-protein kinase SYK isoform X1
       106971657 ATP6V0D1; V-type proton ATPase subunit d 1
       106977246 ATP6V0D2; V-type proton ATPase subunit d 2
       106967793 UBE3A; ubiquitin-protein ligase E3A isoform X2
       106976354 DLG1; disks large homolog 1 isoform X1
       106988832 SCRIB; protein scribble homolog isoform X1
       106971693 PXN; paxillin isoform X3
       106976101 BAK1; bcl-2 homologous antagonist/killer
       106983140 IRF3; interferon regulatory factor 3 isoform X1
       106989365 PSMC1; 26S proteasome regulatory subunit 4
       106971960 RB1; retinoblastoma-associated protein isoform X1
       106979285 RBL1; retinoblastoma-like protein 1 isoform X1
       106984720 RBL2; retinoblastoma-like protein 2
       106965649 CDKN1B; cyclin-dependent kinase inhibitor 1B
       106983377 UBR4; E3 ubiquitin-protein ligase UBR4 isoform X1
       106974986 JUN; transcription factor AP-1
       106965445 CHD4; chromodomain-helicase-DNA-binding protein 4 isoform X1
       106968918 HDAC2; histone deacetylase 2 isoform X1
       106982428 HDAC1; histone deacetylase 1 isoform X2
       106967267 HDAC3; histone deacetylase 3 isoform X1
       106967107 HDAC4; histone deacetylase 4 isoform X1
       106974278 HDAC5; histone deacetylase 5 isoform X1
       106989010 HDAC6; histone deacetylase 6 isoform X1
       106969353 HDAC7; histone deacetylase 7 isoform X1
       106982392 HDAC8; histone deacetylase 8 isoform X7
       106984149 HDAC9; histone deacetylase 9 isoform X1
       106987623 HDAC10; histone deacetylase 10 isoform X1
       106978633 HDAC11; histone deacetylase 11
       106987855 IRF9; interferon regulatory factor 9 isoform X1
       106978810 DNAJA3; dnaJ homolog subfamily A member 3, mitochondrial isoform X1
       106981451 KAT2B; histone acetyltransferase KAT2B isoform X1
       106972603 KAT2A; histone acetyltransferase KAT2A
       106983580 GTF2A1; transcription initiation factor IIA subunit 1
       106977215 GTF2A1L; TFIIA-alpha and beta-like factor
       106973798 GTF2A2; transcription initiation factor IIA subunit 2
       106974034 SRF; serum response factor
       106988817 IKBKG; NF-kappa-B essential modulator isoform X1
       106965509 NFKBIA; NF-kappa-B inhibitor alpha
       106984995 RASA2; ras GTPase-activating protein 2 isoform X1
       106977652 CDC42; cell division control protein 42 homolog isoform X1
       106982604 RAC1; ras-related C3 botulinum toxin substrate 1 isoform X1
       106979239 RHOA; transforming protein RhoA
       106983057 SCIN; adseverin
       106986616 GSN; gelsolin isoform X3
       106980245 ACTN4; alpha-actinin-4 isoform X1
       106971540 ACTN1; alpha-actinin-1 isoform X1
       106975871 CDK4; cyclin-dependent kinase 4 isoform X1
       106986386 cyclin-dependent kinase inhibitor 2A-like
       106986385 CDKN2B; cyclin-dependent kinase 4 inhibitor B
       106976641 CHEK1; serine/threonine-protein kinase Chk1
       106970210 CDC20; cell division cycle protein 20 homolog isoform X1
       106984516 MAD1L1; mitotic spindle assembly checkpoint protein MAD1 isoform X1
       106984356 VAC14; protein VAC14 homolog isoform X1
       106983603 RANBP1; ran-specific GTPase-activating protein isoform X1
       106990013 POLB; DNA polymerase beta
       106988905 IRF7; interferon regulatory factor 7
       106975253 IL6ST; interleukin-6 receptor subunit beta isoform X1
       106969043 C-C chemokine receptor type 5
       106966718 CCR8; C-C chemokine receptor type 8
       106969178 CCR3; C-C chemokine receptor type 3
       106989283 CCR4; C-C chemokine receptor type 4
       106981771 MAPKAPK2; MAP kinase-activated protein kinase 2 isoform X1
       106987995 CASP8; caspase-8
       106981699 BAD; bcl2-associated agonist of cell death
       106978896 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
       106969978 H-2 class I histocompatibility antigen
       106975945 DLA class I histocompatibility antigen
       106966637 LOW QUALITY PROTEIN: DLA class I histocompatibility antigen
       106966627 class I histocompatibility antigen
       106975947 H-2 class I histocompatibility antigen
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04450 ATF2; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B; cyclic AMP-dependent transcription factor ATF-6 beta
K10610 DDB1; DNA damage-binding protein 1
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K06630 YWHAE; 14-3-3 protein epsilon
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K08665 HPN; hepsin [EC:3.4.21.106]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04735 RELA; transcription factor p65
K09254 REL; c-Rel proto-oncogene protein
K04469 NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04451 TP53; tumor protein p53
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K12496 EGR2; early growth response protein 2
K12497 EGR3; early growth response protein 3
K15041 VDAC3; voltage-dependent anion channel protein 3
K03159 TNFRSF3; lymphotoxin beta receptor TNFR superfamily member 3
K15413 SP100; nuclear body protein Sp100
K12886 HNRNPK; heterogeneous nuclear ribonucleoprotein K
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:3.6.4.13]
K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:3.6.4.13]
K16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11252 H2B; histone H2B
K11254 H4; histone H4
K11254 H4; histone H4
K11254 H4; histone H4
K11254 H4; histone H4
K11254 H4; histone H4
K11254 H4; histone H4
K11254 H4; histone H4
K11254 H4; histone H4
K11254 H4; histone H4
K11254 H4; histone H4
K11254 H4; histone H4
K11254 H4; histone H4
K02159 BAX; apoptosis regulator BAX
K04364 GRB2; growth factor receptor-bound protein 2
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
K11838 USP7; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K06053 RBPSUH; recombining binding protein suppressor of hairless
K06053 RBPSUH; recombining binding protein suppressor of hairless
K06063 SNW1; SNW domain-containing protein 1
K03141 TFIIH1; transcription initiation factor TFIIH subunit 1
K03142 TFIIH2; transcription initiation factor TFIIH subunit 2
K03143 TFIIH3; transcription initiation factor TFIIH subunit 3
K03144 TFIIH4; transcription initiation factor TFIIH subunit 4
K03136 TFIIE1; transcription initiation factor TFIIE subunit alpha
K03137 TFIIE2; transcription initiation factor TFIIE subunit beta
K15979 SND1; staphylococcal nuclease domain-containing protein 1
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K03124 TFIIB; transcription initiation factor TFIIB
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06627 CCNA; cyclin-A
K06627 CCNA; cyclin-A
K03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K16174 MRPS18B; small subunit ribosomal protein S18b, mitochondrial
K03172 TRAF1; TNF receptor-associated factor 1
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K03174 TRAF3; TNF receptor-associated factor 3
K09849 TRAF5; TNF receptor-associated factor 5
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K05854 LYN; tyrosine-protein kinase Lyn [EC:2.7.10.2]
K05855 SYK; spleen tyrosine kinase [EC:2.7.10.2]
K02146 ATPeV0D; V-type H+-transporting ATPase subunit d
K02146 ATPeV0D; V-type H+-transporting ATPase subunit d
K10587 UBE3A; ubiquitin-protein ligase E3 A [EC:2.3.2.26]
K12076 DLG1; disks large protein 1
K16175 SCRIB; protein scribble
K05760 PXN; paxillin
K14021 BAK; Bcl-2 homologous antagonist/killer
K05411 IRF3; interferon regulatory factor 3
K03062 PSMC1; 26S proteasome regulatory subunit T2
K06618 RB1; retinoblastoma-associated protein
K04681 RBL1; retinoblastoma-like protein 1
K16332 RBL2; retinoblastoma-like protein 2
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K10691 UBR4; E3 ubiquitin-protein ligase UBR4 [EC:2.3.2.27]
K04448 JUN; transcription factor AP-1
K11643 CHD4; chromodomain-helicase-DNA-binding protein 4 [EC:3.6.4.12]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K11404 HDAC3; histone deacetylase 3 [EC:3.5.1.98]
K11406 HDAC4_5; histone deacetylase 4/5 [EC:3.5.1.98]
K11406 HDAC4_5; histone deacetylase 4/5 [EC:3.5.1.98]
K11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98]
K11408 HDAC7; histone deacetylase 7 [EC:3.5.1.98]
K11405 HDAC8; histone deacetylase 8 [EC:3.5.1.98]
K11409 HDAC9; histone deacetylase 9 [EC:3.5.1.98]
K18671 HDAC10; histone deacetylase 10 [EC:3.5.1.98]
K11418 HDAC11; histone deacetylase 11 [EC:3.5.1.98]
K04693 IRF9; interferon regulatory factor 9
K09504 DNAJA3; DnaJ homolog subfamily A member 3
K06062 PCAF; histone acetyltransferase [EC:2.3.1.48]
K06062 PCAF; histone acetyltransferase [EC:2.3.1.48]
K03122 TFIIA1; transcription initiation factor TFIIA large subunit
K03122 TFIIA1; transcription initiation factor TFIIA large subunit
K03123 TFIIA2; transcription initiation factor TFIIA small subunit
K04378 SRF; serum response factor
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K08053 RASA2; Ras GTPase-activating protein 2
K04393 CDC42; cell division control protein 42
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K04513 RHOA; Ras homolog gene family, member A
K05768 GSN; gelsolin
K05768 GSN; gelsolin
K05699 ACTN1_4; actinin alpha 1/4
K05699 ACTN1_4; actinin alpha 1/4
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K04685 CDKN2B; cyclin-dependent kinase inhibitor 2B
K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
K03363 CDC20; cell division cycle 20, cofactor of APC complex
K06679 MAD1; mitotic spindle assembly checkpoint protein MAD1
K15305 VAC14; vacuole morphology and inheritance protein 14
K15306 RANBP1; Ran-binding protein 1
K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
K09447 IRF7; interferon regulatory factor 7
K05060 IL6ST; interleukin 6 signal transducer
K04180 CCR5; C-C chemokine receptor type 5
K04183 CCR8; C-C chemokine receptor type 8
K04178 CCR3; C-C chemokine receptor type 3
K04179 CCR4; C-C chemokine receptor type 4
K04443 MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K02158 BAD; Bcl-2-antagonist of cell death
K10131 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
     05230 Central carbon metabolism in cancer [PATH:aju05230]
     05231 Choline metabolism in cancer [PATH:aju05231]
     05235 PD-L1 expression and PD-1 checkpoint pathway in cancer [PATH:aju05235]
 
   09162 Cancer: specific types
     05210 Colorectal cancer [PATH:aju05210]
       106968274 GSK3B; glycogen synthase kinase-3 beta isoform X2
       106977359 AXIN1; axin-1 isoform X1
       106975307 AXIN2; axin-2
       106966666 CTNNB1; catenin beta-1
       106973163 APC; adenomatous polyposis coli protein isoform X4
       106983719 APC2; adenomatous polyposis coli protein 2 isoform X1
       106984911 TCF7; transcription factor 7 isoform X1
       106978197 TCF7L1; transcription factor 7-like 1
       106974119 TCF7L2; transcription factor 7-like 2 isoform X1
       106983664 LEF1; lymphoid enhancer-binding factor 1 isoform X3
       106981916 BIRC5; baculoviral IAP repeat-containing protein 5 isoform X1
       106976895 MYC; myc proto-oncogene protein
       106971167 CCND1; G1/S-specific cyclin-D1
       106968778 KRAS; GTPase KRas isoform X1
       106984896 PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1
       106984265 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
       106973880 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
       106976917 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1
       106973297 PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma
       106969150 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
       106979622 AKT2; RAC-beta serine/threonine-protein kinase isoform X1
       106975558 AKT3; RAC-gamma serine/threonine-protein kinase isoform X2
       106985046 AKT1; RAC-alpha serine/threonine-protein kinase isoform X1
       106981699 BAD; bcl2-associated agonist of cell death
       106975594 CASP9; caspase-9 isoform X1
       106972677 ARAF; serine/threonine-protein kinase A-Raf
       106970441 BRAF; serine/threonine-protein kinase B-raf isoform X1
       106977129 RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X1
       106980282 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 isoform X2
       106975474 MAP2K2; dual specificity mitogen-activated protein kinase kinase 2 isoform X1
       106969232 MAPK3; mitogen-activated protein kinase 3 isoform X2
       106990008 MAPK1; mitogen-activated protein kinase 1
       106974986 JUN; transcription factor AP-1
       106974355 FOS; proto-oncogene c-Fos
       106985322 RALGDS; ral guanine nucleotide dissociation stimulator isoform X1
       106989551 ral guanine nucleotide dissociation stimulator-like isoform X1
       113597310 ral guanine nucleotide dissociation stimulator-like
       106974372 RALA; ras-related protein Ral-A
       106966391 RALB; ras-related protein Ral-B
       106982604 RAC1; ras-related C3 botulinum toxin substrate 1 isoform X1
       106981077 RAC2; ras-related C3 botulinum toxin substrate 2 isoform X1
       106986311 RAC3; ras-related C3 botulinum toxin substrate 3 isoform X1
       106979239 RHOA; transforming protein RhoA
       106969894 MAPK9; mitogen-activated protein kinase 9 isoform X1
       106970668 MAPK10; mitogen-activated protein kinase 10 isoform X2
       106989581 MAPK8; mitogen-activated protein kinase 8 isoform X1
       106981192 DCC; netrin receptor DCC isoform X1
       106979326 CASP3; caspase-3 isoform X1
       106967026 APPL1; DCC-interacting protein 13-alpha
       106987682 TGFB1; transforming growth factor beta-1 proprotein isoform X1
       106979500 TGFB2; transforming growth factor beta-2 proprotein isoform X1
       106974351 TGFB3; transforming growth factor beta-3 proprotein isoform X1
       106972043 TGFBR1; TGF-beta receptor type-1 isoform X1
       106984570 TGFBR2; TGF-beta receptor type-2
       106972947 SMAD2; mothers against decapentaplegic homolog 2 isoform X1
       106980367 SMAD3; mothers against decapentaplegic homolog 3 isoform X2
       106974966 SMAD4; mothers against decapentaplegic homolog 4 isoform X1
       106982621 MLH1; DNA mismatch repair protein Mlh1 isoform X1
       106977220 MSH2; DNA mismatch repair protein Msh2
       106972137 MSH3; DNA mismatch repair protein Msh3 isoform X1
       106977218 MSH6; DNA mismatch repair protein Msh6 isoform X1
       106988699 BAX; apoptosis regulator BAX isoform X1
       106978896 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
       106976034 BCL2L11; bcl-2-like protein 11 isoform X1
       106973568 BBC3; bcl-2-binding component 3
       106985187 BCL2; apoptosis regulator Bcl-2
       106988781 cytochrome c
       106982840 cytochrome c
       106986613 cytochrome c-like
       106972437 TP53; cellular tumor antigen p53
       106972797 CDKN1A; cyclin-dependent kinase inhibitor 1
       106989693 GADD45B; growth arrest and DNA damage-inducible protein GADD45 beta
       106985200 GADD45A; growth arrest and DNA damage-inducible protein GADD45 alpha
       113594268 GADD45G; growth arrest and DNA damage-inducible protein GADD45 gamma
       106976101 BAK1; bcl-2 homologous antagonist/killer
       106978021 DDB2; DNA damage-binding protein 2 isoform X1
       106974834 POLK; DNA polymerase kappa isoform X1
       106983657 EGF; pro-epidermal growth factor isoform X1
       106967765 TGFA; protransforming growth factor alpha isoform X1
       106982031 EREG; proepiregulin
       106982023 AREG; amphiregulin
       106976977 EGFR; epidermal growth factor receptor
       106987795 GRB2; growth factor receptor-bound protein 2
       106978987 SOS1; son of sevenless homolog 1 isoform X1
       106989073 SOS2; son of sevenless homolog 2 isoform X1
       106987957 HRAS; GTPase HRas isoform X1
       106969596 NRAS; GTPase NRas
       106984907 MTOR; serine/threonine-protein kinase mTOR isoform X1
       106972702 RPS6KB1; ribosomal protein S6 kinase beta-1 isoform X1
       106971103 RPS6KB2; ribosomal protein S6 kinase beta-2 isoform X1
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02105 CTNNB1; catenin beta 1
K02085 APC; adenomatosis polyposis coli protein
K02085 APC; adenomatosis polyposis coli protein
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K08731 BIRC5; baculoviral IAP repeat-containing protein 5
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; G1/S-specific cyclin-D1
K07827 KRAS; GTPase KRas
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04379 FOS; proto-oncogene protein c-fos
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K07834 RALA; Ras-related protein Ral-A
K07835 RALB; Ras-related protein Ral-B
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04513 RHOA; Ras homolog gene family, member A
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K06765 DCC; deleted in colorectal carcinoma
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K08733 APPL1; DCC-interacting protein 13 alpha
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K08734 MLH1; DNA mismatch repair protein MLH1
K08735 MSH2; DNA mismatch repair protein MSH2
K08736 MSH3; DNA mismatch repair protein MSH3
K08737 MSH6; DNA mismatch repair protein MSH6
K02159 BAX; apoptosis regulator BAX
K10131 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
K16341 BCL2L11; Bcl-2-like protein 11
K10132 BBC3; Bcl-2-binding component 3
K02161 BCL2; apoptosis regulator Bcl-2
K08738 CYC; cytochrome c
K08738 CYC; cytochrome c
K08738 CYC; cytochrome c
K04451 TP53; tumor protein p53
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K14021 BAK; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K09784 EREG; epiregulin
K09782 AREG; amphiregulin
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07828 NRAS; GTPase NRas
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
     05212 Pancreatic cancer [PATH:aju05212]
     05225 Hepatocellular carcinoma [PATH:aju05225]
     05226 Gastric cancer [PATH:aju05226]
     05214 Glioma [PATH:aju05214]
     05216 Thyroid cancer [PATH:aju05216]
     05221 Acute myeloid leukemia [PATH:aju05221]
     05220 Chronic myeloid leukemia [PATH:aju05220]
     05217 Basal cell carcinoma [PATH:aju05217]
     05218 Melanoma [PATH:aju05218]
     05211 Renal cell carcinoma [PATH:aju05211]
     05219 Bladder cancer [PATH:aju05219]
     05215 Prostate cancer [PATH:aju05215]
     05213 Endometrial cancer [PATH:aju05213]
     05224 Breast cancer [PATH:aju05224]
     05222 Small cell lung cancer [PATH:aju05222]
     05223 Non-small cell lung cancer [PATH:aju05223]
 
   09172 Infectious disease: viral
 
   09171 Infectious disease: bacterial
 
   09174 Infectious disease: parasitic
 
   09163 Immune disease
 
   09164 Neurodegenerative disease
 
   09165 Substance dependence
 
   09166 Cardiovascular disease
 
   09167 Endocrine and metabolic disease
 
   09175 Drug resistance: antimicrobial
 
   09176 Drug resistance: antineoplastic
     01521 EGFR tyrosine kinase inhibitor resistance [PATH:aju01521]
     01524 Platinum drug resistance [PATH:aju01524]
       106978326 SLC31A1; high affinity copper uptake protein 1
       106972662 ATP7B; copper-transporting ATPase 2 isoform X1
       106986095 ATP7A; copper-transporting ATPase 1 isoform X2
       106966916 GSTO2; glutathione S-transferase omega-2 isoform X1
       106966917 GSTO1; glutathione S-transferase omega-1
       106977846 glutathione S-transferase Mu 3
       106977852 glutathione S-transferase Mu 4
       106965575 MGST3; microsomal glutathione S-transferase 3
       106965679 MGST1; microsomal glutathione S-transferase 1
       106973067 glutathione S-transferase A2
       106973068 GSTA4; glutathione S-transferase A4
       106973069 glutathione S-transferase A2-like
       106979662 LOW QUALITY PROTEIN: glutathione S-transferase theta-2B-like
       106979690 glutathione S-transferase theta-1 isoform X1
       106979693 glutathione S-transferase theta-1-like
       106976197 MGST2; microsomal glutathione S-transferase 2
       106979691 glutathione S-transferase theta-4
       113592407 glutathione S-transferase theta-3-like isoform X1
       106973070 glutathione S-transferase A4-like isoform X1
       106971176 glutathione S-transferase P
       106966857 ABCC2; canalicular multispecific organic anion transporter 1 isoform X1
       106974021 POLH; DNA polymerase eta
       106968905 REV3L; DNA polymerase zeta catalytic subunit isoform X1
       106977220 MSH2; DNA mismatch repair protein Msh2
       106972137 MSH3; DNA mismatch repair protein Msh3 isoform X1
       106977218 MSH6; DNA mismatch repair protein Msh6 isoform X1
       106982621 MLH1; DNA mismatch repair protein Mlh1 isoform X1
       106981243 XPA; DNA repair protein complementing XP-A cells isoform X1
       106973646 ERCC1; DNA excision repair protein ERCC-1 isoform X1
       106980548 TOP2A; DNA topoisomerase 2-alpha
       106988242 TOP2B; DNA topoisomerase 2-beta isoform X1
       106972629 BRCA1; breast cancer type 1 susceptibility protein isoform X1
       106983963 ATM; serine-protein kinase ATM isoform X1
       106972437 TP53; cellular tumor antigen p53
       106986386 cyclin-dependent kinase inhibitor 2A-like
       106966348 MDM2; E3 ubiquitin-protein ligase Mdm2 isoform X3
       106980953 FAS; tumor necrosis factor receptor superfamily member 6 isoform X1
       106988699 BAX; apoptosis regulator BAX isoform X1
       106976101 BAK1; bcl-2 homologous antagonist/killer
       106978896 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
       106973568 BBC3; bcl-2-binding component 3
       106979842 FASLG; tumor necrosis factor ligand superfamily member 6
       106982870 FADD; FAS-associated death domain protein
       106987995 CASP8; caspase-8
       106979326 CASP3; caspase-3 isoform X1
       106968455 BID; BH3-interacting domain death agonist
       106976507 baculoviral IAP repeat-containing protein 3-like
       106976508 BIRC2; baculoviral IAP repeat-containing protein 2
       106972832 XIAP; E3 ubiquitin-protein ligase XIAP
       106981916 BIRC5; baculoviral IAP repeat-containing protein 5 isoform X1
       106980462 ERBB2; receptor tyrosine-protein kinase erbB-2 isoform X1
       106984896 PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1
       106984265 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
       106973880 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
       106976917 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1
       106973297 PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma
       106969150 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
       106978772 PDPK1; 3-phosphoinositide-dependent protein kinase 1 isoform X4
       106979622 AKT2; RAC-beta serine/threonine-protein kinase isoform X1
       106975558 AKT3; RAC-gamma serine/threonine-protein kinase isoform X2
       106985046 AKT1; RAC-alpha serine/threonine-protein kinase isoform X1
       106972797 CDKN1A; cyclin-dependent kinase inhibitor 1
       106983673 MAP3K5; mitogen-activated protein kinase kinase kinase 5 isoform X1
       106969232 MAPK3; mitogen-activated protein kinase 3 isoform X2
       106990008 MAPK1; mitogen-activated protein kinase 1
       106981699 BAD; bcl2-associated agonist of cell death
       106986010 BCL2L1; bcl-2-like protein 1
       106985187 BCL2; apoptosis regulator Bcl-2
       106988781 cytochrome c
       106982840 cytochrome c
       106986613 cytochrome c-like
       106973746 APAF1; apoptotic protease-activating factor 1 isoform X1
       106975594 CASP9; caspase-9 isoform X1
K14686 SLC31A1; solute carrier family 31 (copper transporter), member 1
K17686 copA; P-type Cu+ transporter [EC:7.2.2.8]
K17686 copA; P-type Cu+ transporter [EC:7.2.2.8]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K23790 GSTP; glutathione S-transferase P [EC:2.5.1.18]
K05666 ABCC2; ATP-binding cassette, subfamily C (CFTR/MRP), member 2
K03509 POLH; DNA polymerase eta [EC:2.7.7.7]
K02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]
K08735 MSH2; DNA mismatch repair protein MSH2
K08736 MSH3; DNA mismatch repair protein MSH3
K08737 MSH6; DNA mismatch repair protein MSH6
K08734 MLH1; DNA mismatch repair protein MLH1
K10847 XPA; DNA-repair protein complementing XP-A cells
K10849 ERCC1; DNA excision repair protein ERCC-1
K03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]
K03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]
K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K04451 TP53; tumor protein p53
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04390 TNFRSF6; tumor necrosis factor receptor superfamily member 6
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K10131 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
K10132 BBC3; Bcl-2-binding component 3
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04726 BID; BH3 interacting domain death agonist
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04725 XIAP; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K08731 BIRC5; baculoviral IAP repeat-containing protein 5
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04426 MAP3K5; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K02158 BAD; Bcl-2-antagonist of cell death
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K02161 BCL2; apoptosis regulator Bcl-2
K08738 CYC; cytochrome c
K08738 CYC; cytochrome c
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
     01523 Antifolate resistance [PATH:aju01523]
     01522 Endocrine resistance [PATH:aju01522]
 
 09180 Brite Hierarchies
 
 09190 Not Included in Pathway or Brite

[ KO | BRITE | KEGG2 | KEGG ]
Last updated: March 1, 2021