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KO |
 09100 Metabolism
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09120 Genetic Information Processing
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 09130 Environmental Information Processing
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09131 Membrane transport
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09132 Signal transduction
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 02020 Two-component system
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04010 MAPK signaling pathway [PATH:nle04010]
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04013 MAPK signaling pathway - fly
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04016 MAPK signaling pathway - plant
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04011 MAPK signaling pathway - yeast
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04012 ErbB signaling pathway [PATH:nle04012]
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04014 Ras signaling pathway [PATH:nle04014]
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100588963 EGF; pro-epidermal growth factor isoform X1
100607585 TGFA; protransforming growth factor alpha isoform X3
100603200 FGF1; LOW QUALITY PROTEIN: fibroblast growth factor 1
100593123 FGF2; fibroblast growth factor 2 isoform X1
100588427 FGF18; fibroblast growth factor 18
100598611 FGF8; fibroblast growth factor 8 isoform X1
100587475 FGF4; fibroblast growth factor 4
100587808 FGF3; fibroblast growth factor 3
100603249 FGF20; fibroblast growth factor 20
100601992 FGF9; fibroblast growth factor 9
100580620 FGF7; fibroblast growth factor 7
100605698 fibroblast growth factor 6
100590822 FGF10; fibroblast growth factor 10
100591900 FGF17; fibroblast growth factor 17 isoform X1
100585623 FGF16; fibroblast growth factor 16
100583276 FGF5; fibroblast growth factor 5 isoform X1
100598059 FGF22; fibroblast growth factor 22 isoform X2
100606867 FGF19; fibroblast growth factor 19
100590773 FGF21; fibroblast growth factor 21
100605361 FGF23; fibroblast growth factor 23
100593913 NGF; beta-nerve growth factor
100594402 BDNF; brain-derived neurotrophic factor isoform X3
100580195 NTF3; neurotrophin-3 isoform X2
100593584 NTF4; neurotrophin-4
100586809 INS; insulin isoform X2
100595306 IGF1; insulin-like growth factor I isoform X3
100585821 IGF2; insulin-like growth factor II isoform X2
100583683 PDGFA; platelet-derived growth factor subunit A isoform X6
100586714 PDGFB; platelet-derived growth factor subunit B
100585549 PDGFC; platelet-derived growth factor C isoform X1
100586178 PDGFD; platelet-derived growth factor D isoform X1
100590081 CSF1; macrophage colony-stimulating factor 1 isoform X1
100587810 KITLG; kit ligand
100601396 VEGFA; vascular endothelial growth factor A isoform X1
100599288 VEGFB; vascular endothelial growth factor B isoform X2
100600228 PGF; placenta growth factor isoform X1
100601827 VEGFD; vascular endothelial growth factor D
100595914 VEGFC; vascular endothelial growth factor C
100586296 HGF; hepatocyte growth factor isoform X1
100581421 ANGPT1; angiopoietin-1 isoform X1
100591550 ANGPT2; angiopoietin-2 isoform X2
100606614 EFNA5; ephrin-A5 isoform X1
100584794 EFNA1; ephrin-A1
100583129 EFNA3; ephrin-A3 isoform X1
100582330 EFNA4; ephrin-A4 isoform X3
100600655 EFNA2; ephrin-A2
100597255 EGFR; epidermal growth factor receptor isoform X1
100602423 FGFR1; fibroblast growth factor receptor 1 isoform X1
100598157 FGFR2; fibroblast growth factor receptor 2 isoform X1
100591839 FGFR3; fibroblast growth factor receptor 3 isoform X1
100582351 FGFR4; fibroblast growth factor receptor 4
100597065 NGFR; tumor necrosis factor receptor superfamily member 16
100585466 NTRK1; high affinity nerve growth factor receptor
100605330 NTRK2; BDNF/NT-3 growth factors receptor isoform X1
100597533 INSR; insulin receptor isoform X1
100593288 IGF1R; insulin-like growth factor 1 receptor isoform X1
100603207 PDGFRA; platelet-derived growth factor receptor alpha
100597894 PDGFRB; platelet-derived growth factor receptor beta
100598906 CSF1R; macrophage colony-stimulating factor 1 receptor isoform X1
100603893 KIT; mast/stem cell growth factor receptor Kit isoform X3
100589184 FLT3; receptor-type tyrosine-protein kinase FLT3 isoform X1
100590200 FLT1; vascular endothelial growth factor receptor 1 isoform X1
100582920 FLT4; vascular endothelial growth factor receptor 3
100604569 KDR; vascular endothelial growth factor receptor 2
100597172 MET; hepatocyte growth factor receptor isoform X3
100606897 TEK; angiopoietin-1 receptor isoform X1
100591506 EPHA2; ephrin type-A receptor 2
100588468 GRB2; growth factor receptor-bound protein 2
100600534 GAB1; GRB2-associated-binding protein 1 isoform X4
100581971 GAB2; GRB2-associated-binding protein 2 isoform X1
100606068 SHC1; SHC-transforming protein 1 isoform X1
100591489 SHC2; SHC-transforming protein 2 isoform X1
100589484 SHC3; SHC-transforming protein 3 isoform X3
100591644 SHC4; SHC-transforming protein 4
100602671 PTPN11; tyrosine-protein phosphatase non-receptor type 11 isoform X1
100605369 LOW QUALITY PROTEIN: tyrosine-protein phosphatase non-receptor type 11-like
100590165 SOS1; son of sevenless homolog 1 isoform X1
100600495 SOS2; LOW QUALITY PROTEIN: son of sevenless homolog 2
100591458 PLCG1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1
100604145 PLCG2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
100584529 RASGRP1; RAS guanyl-releasing protein 1
100603817 RASGRP2; RAS guanyl-releasing protein 2 isoform X2
100603635 RASGRP3; ras guanyl-releasing protein 3
100590994 RASGRP4; RAS guanyl-releasing protein 4 isoform X2
101179555 uncharacterized protein LOC101179555
101175807 uncharacterized protein LOC101175807
101176031 uncharacterized protein LOC101176031
101177905 uncharacterized protein LOC101177905
100589243 tyrosine-protein kinase ZAP-70 isoform X1
100605633 LAT; linker for activation of T-cells family member 1 isoform X3
100585771 HTR7; 5-hydroxytryptamine receptor 7 isoform X1
100583137 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
100590367 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 isoform X1
100596905 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
100589215 GNB4; guanine nucleotide-binding protein subunit beta-4
100594371 GNB5; guanine nucleotide-binding protein subunit beta-5 isoform X1
100579945 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
100579986 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
100591313 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
100586578 guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
115837666 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
115830866 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
115833531 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
115834702 guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10-like
100581702 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
100593358 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
100584569 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
115836971 GNG14; LOW QUALITY PROTEIN: putative guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-14
115831194 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
115834220 guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
100592009 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
115833576 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
100583577 PRKACB; cAMP-dependent protein kinase catalytic subunit beta isoform X8
100579779 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha
100607741 PRKACG; LOW QUALITY PROTEIN: cAMP-dependent protein kinase catalytic subunit gamma
100597935 RASGRF1; ras-specific guanine nucleotide-releasing factor 1 isoform X1
100590607 RASGRF2; ras-specific guanine nucleotide-releasing factor 2
100607572 GRIN1; glutamate receptor ionotropic, NMDA 1 isoform X1
100584731 GRIN2A; glutamate receptor ionotropic, NMDA 2A isoform X1
100594244 GRIN2B; glutamate receptor ionotropic, NMDA 2B
100586234 calmodulin-like
100582584 CALM2; calmodulin-2
100584686 CALML6; calmodulin-like protein 6
100595594 CALM1; calmodulin-1
100607765 CALML3; calmodulin-like protein 3
100602246 CALM3; calmodulin-3
100588287 CALML4; calmodulin-like protein 4 isoform X1
100603253 CALML5; calmodulin-like protein 5
100595274 HRAS; GTPase HRas isoform X1
100593773 KRAS; GTPase KRas isoform X1
100592103 NRAS; GTPase NRas
100581488 MRAS; ras-related protein M-Ras
100602757 RRAS; ras-related protein R-Ras
100604922 RRAS2; ras-related protein R-Ras2 isoform X1
100603967 NF1; neurofibromin isoform X3
100582242 RASA1; ras GTPase-activating protein 1 isoform X1
100595161 RASA2; ras GTPase-activating protein 2 isoform X1
100580920 RASA3; ras GTPase-activating protein 3
100584886 RASA4B; ras GTPase-activating protein 4B isoform X1
100588148 SYNGAP1; ras/Rap GTPase-activating protein SynGAP isoform X1
100603358 RASAL1; rasGAP-activating-like protein 1
100585112 RASAL2; ras GTPase-activating protein nGAP isoform X1
100591699 RASAL3; RAS protein activator like-3
100592827 RASSF1; ras association domain-containing protein 1 isoform X1
100607511 RASSF5; ras association domain-containing protein 5 isoform X1
100599164 STK4; serine/threonine-protein kinase 4
100605316 TIAM1; T-lymphoma invasion and metastasis-inducing protein 1 isoform X1
100604516 RAC1; ras-related C3 botulinum toxin substrate 1
100598232 RAC2; ras-related C3 botulinum toxin substrate 2
100602123 RAC3; ras-related C3 botulinum toxin substrate 3 isoform X3
100588769 PAK1; serine/threonine-protein kinase PAK 1 isoform X2
100601244 PAK2; serine/threonine-protein kinase PAK 2
100592637 PAK3; serine/threonine-protein kinase PAK 3 isoform X2
100597455 PAK4; serine/threonine-protein kinase PAK 4 isoform X1
100579630 PAK5; serine/threonine-protein kinase PAK 5 isoform X1
100579258 PAK6; serine/threonine-protein kinase PAK 6
100607291 RHOA; transforming protein RhoA
100588218 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
100580872 PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1
100584384 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1
100605788 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1
100591270 PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1
100599301 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
100604331 AKT3; RAC-gamma serine/threonine-protein kinase isoform X1
100587864 AKT2; RAC-beta serine/threonine-protein kinase isoform X1
100587109 AKT1; RAC-alpha serine/threonine-protein kinase
100603768 IKBKG; NF-kappa-B essential modulator isoform X1
100596225 CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1
100588081 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1
100581655 NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1
100588439 RELA; transcription factor p65
101178725 BAD; bcl2-associated agonist of cell death
100595330 BCL2L1; bcl-2-like protein 1
100586421 FOXO4; forkhead box protein O4
100597719 FASLG; tumor necrosis factor ligand superfamily member 6 isoform X1
100592208 AFDN; afadin isoform X1
100585185 SHOC2; leucine-rich repeat protein SHOC-2
100582599 RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X1
100579506 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1
100591827 MAP2K2; dual specificity mitogen-activated protein kinase kinase 2
100600574 MAPK1; mitogen-activated protein kinase 1
100584480 MAPK3; mitogen-activated protein kinase 3
100602828 PLA1A; phospholipase A1 member A
100591114 PLA2G12A; group XIIA secretory phospholipase A2
100583584 PLA2G1B; phospholipase A2
100601293 PLA2G2C; LOW QUALITY PROTEIN: putative inactive group IIC secretory phospholipase A2
100596670 PLA2G5; calcium-dependent phospholipase A2 isoform X2
100597118 PLA2G2D; group IID secretory phospholipase A2
100597459 PLA2G2F; group IIF secretory phospholipase A2
100595649 PLA2G2A; phospholipase A2, membrane associated
100595315 PLA2G2E; group IIE secretory phospholipase A2
100585880 PLA2G3; group 3 secretory phospholipase A2
101179281 PLA2G10; group 10 secretory phospholipase A2
100599603 PLA2G12B; group XIIB secretory phospholipase A2-like protein isoform X1
115831166 group 10 secretory phospholipase A2-like
100593575 PLA2G4D; cytosolic phospholipase A2 delta
100593907 PLA2G4F; cytosolic phospholipase A2 zeta
100591987 cytosolic phospholipase A2 beta isoform X1
100593220 PLA2G4E; cytosolic phospholipase A2 epsilon
100591421 PLA2G4A; cytosolic phospholipase A2
100587969 PLA2G4C; cytosolic phospholipase A2 gamma
100605211 PLA2G6; 85/88 kDa calcium-independent phospholipase A2 isoform X3
100593041 PLAAT3; phospholipase A and acyltransferase 3
100592698 PLAAT2; phospholipase A and acyltransferase 2
100596002 ELK1; ETS domain-containing protein Elk-1
100606580 ETS1; protein C-ets-1 isoform X2
100605656 ETS2; protein C-ets-2
100593077 BRAP; BRCA1-associated protein isoform X1
100589332 KSR1; kinase suppressor of Ras 1 isoform X1
100597930 KSR2; kinase suppressor of Ras 2 isoform X1
100585636 RAPGEF5; rap guanine nucleotide exchange factor 5 isoform X1
100603891 RAP1A; ras-related protein Rap-1A
100593411 RAP1B; ras-related protein Rap-1b
100589231 RALGDS; ral guanine nucleotide dissociation stimulator isoform X1
100579487 LOW QUALITY PROTEIN: ral-GDS-related protein
115835869 LOW QUALITY PROTEIN: ral-GDS-related protein-like
100582259 RGL1; ral guanine nucleotide dissociation stimulator-like 1 isoform X1
100582293 RGL2; ral guanine nucleotide dissociation stimulator-like 2 isoform X1
100603441 RALA; ras-related protein Ral-A
100593053 RALB; ras-related protein Ral-B
100581677 MAPK9; mitogen-activated protein kinase 9 isoform X1
100605285 MAPK8; mitogen-activated protein kinase 8 isoform X1
100602081 MAPK10; mitogen-activated protein kinase 10 isoform X2
100590783 EXOC2; exocyst complex component 2 isoform X1
100582856 TBK1; serine/threonine-protein kinase TBK1
100601719 REL; proto-oncogene c-Rel isoform X1
100605600 PLD1; phospholipase D1
100601695 PLD2; phospholipase D2 isoform X1
100600679 RALBP1; ralA-binding protein 1
100605245 CDC42; cell division control protein 42 homolog isoform X1
100599747 PLCE1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X4
100591651 PRKCA; protein kinase C alpha type isoform X1
100590939 PRKCB; protein kinase C beta type isoform X2
100601464 PRKCG; protein kinase C gamma type
100592356 RIN1; ras and Rab interactor 1 isoform X1
100601002 ABL1; tyrosine-protein kinase ABL1 isoform X1
100588798 ABL2; tyrosine-protein kinase ABL2 isoform X1
100585666 RAB5A; ras-related protein Rab-5A
100593361 RAB5B; ras-related protein Rab-5B
115830348 RAB5C; ras-related protein Rab-5C
100598238 ARF6; ADP-ribosylation factor 6
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K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K02582 NGFB; nerve growth factor, beta
K04355 BDNF; brain-derived neurotrophic factor
K04356 NTF3; neurotrophin 3
K12457 NTF4; neurotrophin 4
K04526 INS; insulin
K05459 IGF1; insulin-like growth factor 1
K13769 IGF2; insulin-like growth factor 2
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K05450 PDGFC_D; platelet derived growth factor C/D
K05450 PDGFC_D; platelet derived growth factor C/D
K05453 CSF1; macrophage colony-stimulating factor 1
K05461 KITLG; KIT ligand
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K16859 PGF; placenta growth factor
K05449 VEGFC_D; vascular endothelial growth factor C/D
K05449 VEGFC_D; vascular endothelial growth factor C/D
K05460 HGF; hepatocyte growth factor
K05465 ANGPT1; angiopoietin 1
K05466 ANGPT2; angiopoietin 2
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K04362 FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K02583 NGFR; tumor necrosis factor receptor superfamily member 16
K03176 NTRK1; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K04360 NTRK2; neurotrophic tyrosine kinase receptor type 2 [EC:2.7.10.1]
K04527 INSR; insulin receptor [EC:2.7.10.1]
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04363 PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05090 CSF1R; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K05091 KIT; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K05092 FLT3; fms-related tyrosine kinase 3 [EC:2.7.10.1]
K05096 FLT1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
K05097 FLT4; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K05098 KDR; kinase insert domain protein receptor [EC:2.7.10.1]
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K05121 TEK; endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]
K05103 EPHA2; Eph receptor A2 [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K09593 GAB1; GRB2-associated-binding protein 1
K08091 GAB2; GRB2-associated-binding protein 2
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K07293 PTPN11; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K07293 PTPN11; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K04350 RASGRP1; RAS guanyl-releasing protein 1
K12361 RASGRP2; RAS guanyl-releasing protein 2
K12362 RASGRP3; RAS guanyl-releasing protein 3
K12363 RASGRP4; RAS guanyl-releasing protein 4
K10785 TRBV; T-cell receptor beta chain V region
K10785 TRBV; T-cell receptor beta chain V region
K10785 TRBV; T-cell receptor beta chain V region
K10785 TRBV; T-cell receptor beta chain V region
K07360 ZAP70; tyrosine-protein kinase ZAP-70 [EC:2.7.10.2]
K07362 LAT; linker for activation of T cells
K04163 HTR7; 5-hydroxytryptamine receptor 7
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04349 RASGRF1; Ras-specific guanine nucleotide-releasing factor 1
K12326 RASGRF2; Ras-specific guanine nucleotide-releasing factor 2
K05208 GRIN1; glutamate receptor ionotropic, NMDA 1
K05209 GRIN2A; glutamate receptor ionotropic, NMDA 2A
K05210 GRIN2B; glutamate receptor ionotropic, NMDA 2B
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K07831 MRAS; Ras-related protein M-Ras
K07829 RRAS; Ras-related protein R-Ras
K07830 RRAS2; Ras-related protein R-Ras2
K08052 NF1; neurofibromin 1
K04352 RASA1; Ras GTPase-activating protein 1
K08053 RASA2; Ras GTPase-activating protein 2
K12380 RASA3; Ras GTPase-activating protein 3
K17630 RASA4; Ras GTPase-activating protein 4
K17631 SYNGAP; Ras/Rap GTPase-activating protein SynGAP
K17632 RASAL1; RAS protein activator-like 1
K17633 RASAL2; RAS protein activator-like 2
K17634 RASAL3; RAS protein activator-like 3
K09850 RASSF1; Ras association domain-containing protein 1
K08015 RASSF5; Ras association domain-containing protein 5
K04411 STK4; serine/threonine kinase 4
K05731 TIAM1; T-lymphoma invasion and metastasis-inducing protein 1
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04410 PAK2; p21-activated kinase 2 [EC:2.7.11.1]
K05733 PAK3; p21-activated kinase 3 [EC:2.7.11.1]
K05734 PAK4; p21-activated kinase 4 [EC:2.7.11.1]
K05736 PAK5; p21-activated kinase 5 [EC:2.7.11.1]
K05735 PAK6; p21-activated kinase 6 [EC:2.7.11.1]
K04513 RHOA; Ras homolog gene family, member A
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K02158 BAD; Bcl-2-antagonist of cell death
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K12358 FOXO4; forkhead box protein O4
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K05702 AF6; afadin
K19613 SHOC2; leucine-rich repeat protein SHOC2
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K13618 PLA1A; phosphatidylserine sn-1 acylhydrolase [EC:3.1.1.111]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16343 PLA2G6; calcium-independent phospholipase A2 [EC:3.1.1.4]
K16817 PLA2G16; HRAS-like suppressor 3 [EC:3.1.1.32 3.1.1.4]
K16817 PLA2G16; HRAS-like suppressor 3 [EC:3.1.1.32 3.1.1.4]
K04375 ELK1; ETS domain-containing protein Elk-1
K02678 ETS1; C-ets-1
K21932 ETS2; C-ets-2
K10632 BRAP; BRCA1-associated protein [EC:2.3.2.27]
K14958 KSR1; kinase suppressor of Ras 1
K18529 KSR2; kinase suppressor of Ras 2 [EC:2.7.11.1]
K08019 RAPGEF5; Rap guanine nucleotide exchange factor 5
K04353 RAP1A; Ras-related protein Rap-1A
K07836 RAP1B; Ras-related protein Rap-1B
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K17635 RGL1; ral guanine nucleotide dissociation stimulator-like 1
K17636 RGL2; ral guanine nucleotide dissociation stimulator-like 2
K07834 RALA; Ras-related protein Ral-A
K07835 RALB; Ras-related protein Ral-B
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K17637 EXOC2; exocyst complex component 2
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K09254 REL; c-Rel proto-oncogene protein
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K08773 RALBP1; RalA-binding protein 1
K04393 CDC42; cell division control protein 42
K05860 PLCE; phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K17638 RIN1; Ras and Rab interactor 1
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K08887 ABL2; abelson tyrosine-protein kinase 2 [EC:2.7.10.2]
K07887 RAB5A; Ras-related protein Rab-5A
K07888 RAB5B; Ras-related protein Rab-5B
K07889 RAB5C; Ras-related protein Rab-5C
K07941 ARF6; ADP-ribosylation factor 6
|
04015 Rap1 signaling pathway [PATH:nle04015]
|
04310 Wnt signaling pathway [PATH:nle04310]
|
04330 Notch signaling pathway [PATH:nle04330]
|
04340 Hedgehog signaling pathway [PATH:nle04340]
|
04341 Hedgehog signaling pathway - fly
|
04350 TGF-beta signaling pathway [PATH:nle04350]
|
04390 Hippo signaling pathway [PATH:nle04390]
|
100594358 CRB2; protein crumbs homolog 2 isoform X1
100601606 CRB1; protein crumbs homolog 1 isoform X3
100592712 PARD3; partitioning defective 3 homolog isoform X1
100586482 PARD6A; partitioning defective 6 homolog alpha isoform X6
100597121 PARD6B; partitioning defective 6 homolog beta
100585698 PRKCZ; protein kinase C zeta type isoform X1
100599635 PRKCI; protein kinase C iota type isoform X1
100591308 PATJ; inaD-like protein
100588054 MPP5; MAGUK p55 subfamily member 5 isoform X1
100599109 AMOT; angiomotin isoform X2
100607618 YAP1; transcriptional coactivator YAP1 isoform X12
100592028 WWTR1; WW domain-containing transcription regulator protein 1
100596627 CDH1; cadherin-1 isoform X1
100605716 LIMD1; LIM domain-containing protein 1
100590380 WTIP; Wilms tumor protein 1-interacting protein isoform X1
100587239 AJUBA; LIM domain-containing protein ajuba
100599082 NF2; merlin isoform X1
100603663 WWC1; protein KIBRA isoform X1
100592876 FRMD1; FERM domain-containing protein 1
100607824 FRMD6; FERM domain-containing protein 6 isoform X2
100603888 SAV1; protein salvador homolog 1 isoform X1
100587096 STK3; serine/threonine-protein kinase 3
100585609 RASSF6; ras association domain-containing protein 6 isoform X1
100592827 RASSF1; ras association domain-containing protein 1 isoform X1
100596525 PPP2CA; serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
100585393 PPP2CB; serine/threonine-protein phosphatase 2A catalytic subunit beta isoform
100605248 PPP2R1B; LOW QUALITY PROTEIN: serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform
100598916 PPP2R1A; serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform
100584267 PPP2R2B; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform isoform X2
100585667 PPP2R2D; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform isoform X1
100583131 PPP2R2C; protein phosphatase 2, regulatory subunit B, gamma isoform X5
100583311 PPP2R2A; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform isoform X1
100599863 LATS1; serine/threonine-protein kinase LATS1 isoform X1
100594910 LATS2; serine/threonine-protein kinase LATS2
100584060 MOB1A; MOB kinase activator 1A isoform X1
100579837 MOB1B; MOB kinase activator 1B
100603005 PPP1CA; serine/threonine-protein phosphatase PP1-alpha catalytic subunit
100605408 PPP1CC; serine/threonine-protein phosphatase PP1-gamma catalytic subunit isoform X1
100587142 PPP1CB; serine/threonine-protein phosphatase PP1-beta catalytic subunit
100589440 TP53BP2; apoptosis-stimulating of p53 protein 2
101179420 LLGL2; lethal(2) giant larvae protein homolog 2 isoform X1
100594687 LLGL1; lethal(2) giant larvae protein homolog 1 isoform X1
100607109 SCRIB; protein scribble homolog isoform X1
100603856 DLG1; disks large homolog 1 isoform X20
100590895 DLG2; disks large homolog 2 isoform X18
100583755 DLG3; disks large homolog 3 isoform X1
100585245 DLG4; disks large homolog 4 isoform X3
100582992 DLG5; disks large homolog 5 isoform X1
100604834 CSNK1D; casein kinase I isoform X1
100607246 casein kinase I isoform X1
100605260 FBXW11; F-box/WD repeat-containing protein 11 isoform X7
100583099 BTRC; F-box/WD repeat-containing protein 1A isoform X1
105738061 TP73; tumor protein p73
100588342 BBC3; bcl-2-binding component 3 isoform X1
100598874 TEAD3; transcriptional enhancer factor TEF-5
100597345 TEAD2; transcriptional enhancer factor TEF-4 isoform X1
100600190 TEAD1; transcriptional enhancer factor TEF-1 isoform X3
100601311 TEAD4; transcriptional enhancer factor TEF-3 isoform X1
115832281 chromatin-remodeling ATPase INO80-like
100604830 CCN2; CCN family member 2
100593982 GLI2; zinc finger protein GLI2
100590072 AREG; amphiregulin
100598415 BIRC5; baculoviral IAP repeat-containing protein 5 isoform X1
100584939 AFP; alpha-fetoprotein
100600337 ITGB2; integrin beta-2 isoform X1
100603200 FGF1; LOW QUALITY PROTEIN: fibroblast growth factor 1
100581386 TGFB1; transforming growth factor beta-1 proprotein isoform X2
100596183 TGFB2; transforming growth factor beta-2 proprotein isoform X1
100591391 TGFB3; transforming growth factor beta-3 proprotein
100592854 TGFBR1; TGF-beta receptor type-1 isoform X1
100606849 TGFBR2; TGF-beta receptor type-2 isoform X2
100592660 SMAD7; mothers against decapentaplegic homolog 7 isoform X1
100589735 SMAD2; mothers against decapentaplegic homolog 2 isoform X1
100583279 SMAD3; mothers against decapentaplegic homolog 3 isoform X1
100599586 SMAD4; mothers against decapentaplegic homolog 4 isoform X1
100588010 SERPINE1; plasminogen activator inhibitor 1 isoform X1
100586297 BMP2; bone morphogenetic protein 2
100586277 BMP4; bone morphogenetic protein 4 isoform X1
100602445 BMP5; bone morphogenetic protein 5 isoform X1
100589085 BMP6; bone morphogenetic protein 6
100606349 BMP7; bone morphogenetic protein 7
100605261 BMP8B; bone morphogenetic protein 8B isoform X1
115837551 BMP8A; bone morphogenetic protein 8A
100605144 GDF5; growth/differentiation factor 5
100604568 GDF6; growth/differentiation factor 6
100607070 GDF7; growth/differentiation factor 7
100606390 AMH; muellerian-inhibiting factor
100583682 BMPR1A; bone morphogenetic protein receptor type-1A isoform X1
100595681 BMPR1B; bone morphogenetic protein receptor type-1B isoform X1
100599616 BMPR2; bone morphogenetic protein receptor type-2
100606054 SMAD1; mothers against decapentaplegic homolog 1 isoform X1
100584308 ID1; DNA-binding protein inhibitor ID-1
100602551 ID2; DNA-binding protein inhibitor ID-2
100587307 WNT1; proto-oncogene Wnt-1
100607954 WNT2B; protein Wnt-2b isoform X2
100600353 WNT2; protein Wnt-2
100606846 WNT3A; protein Wnt-3a isoform X2
100599381 WNT3; proto-oncogene Wnt-3
100604353 WNT4; protein Wnt-4 isoform X1
100602014 WNT5A; protein Wnt-5a
100596686 WNT5B; protein Wnt-5b
100606818 WNT6; protein Wnt-6
100579580 WNT7B; protein Wnt-7b isoform X1
100593900 WNT7A; protein Wnt-7a
100586052 WNT8A; protein Wnt-8a isoform X2
100603238 WNT8B; protein Wnt-8b
100606502 WNT9A; protein Wnt-9a
100602760 WNT9B; protein Wnt-9b isoform X1
100607164 WNT10A; protein Wnt-10a
100587640 WNT10B; protein Wnt-10b
100594864 WNT11; protein Wnt-11
100605294 WNT16; protein Wnt-16 isoform X1
100597685 FZD7; frizzled-7
100605346 FZD1; frizzled-1
100580071 FZD2; frizzled-2
100589994 FZD3; frizzled-3
100588311 FZD4; frizzled-4
100589091 FZD5; frizzled-5
100593717 FZD8; frizzled-8
100603705 FZD6; frizzled-6
100607762 FZD10; frizzled-10
100592375 FZD9; frizzled-9
100585595 DVL2; segment polarity protein dishevelled homolog DVL-2
100583216 DVL3; segment polarity protein dishevelled homolog DVL-3
100593186 DVL1; segment polarity protein dishevelled homolog DVL-1 isoform X1
100598365 YWHAB; 14-3-3 protein beta/alpha isoform X2
100596460 YWHAZ; 14-3-3 protein zeta/delta isoform X1
100605817 YWHAQ; 14-3-3 protein theta
100600918 YWHAE; 14-3-3 protein epsilon isoform X1
100583245 14-3-3 protein epsilon-like
100592606 YWHAH; 14-3-3 protein eta
100600999 YWHAG; 14-3-3 protein gamma
100606885 GSK3B; glycogen synthase kinase-3 beta isoform X1
100583002 CTNNB1; catenin beta-1 isoform X1
100602025 APC2; adenomatous polyposis coli protein 2 isoform X1
100585467 APC; adenomatous polyposis coli protein isoform X3
101179424 AXIN1; axin-1 isoform X1
100589482 AXIN2; axin-2 isoform X1
100589602 NKD1; protein naked cuticle homolog 1
100595277 NKD2; protein naked cuticle homolog 2
100595737 TCF7; LOW QUALITY PROTEIN: transcription factor 7
100601518 TCF7L1; transcription factor 7-like 1
100605701 TCF7L2; transcription factor 7-like 2 isoform X1
100593051 LEF1; lymphoid enhancer-binding factor 1 isoform X3
100589322 MYC; myc proto-oncogene protein
100605736 CCND1; G1/S-specific cyclin-D1
100585770 CCND2; G1/S-specific cyclin-D2
100580170 CCND3; G1/S-specific cyclin-D3 isoform X1
100597138 SOX2; transcription factor SOX-2
100584459 SNAI2; zinc finger protein SNAI2
100579740 BIRC3; baculoviral IAP repeat-containing protein 3
100580307 BIRC2; baculoviral IAP repeat-containing protein 2
100598167 ACTG1; actin, cytoplasmic 2
100598411 ACTB; actin, cytoplasmic 1
100606736 CTNNA3; catenin alpha-3 isoform X1
100599144 CTNNA2; catenin alpha-2 isoform X5
100593453 CTNNA1; catenin alpha-1 isoform X1
|
K16681 CRB; protein crumbs
K16681 CRB; protein crumbs
K04237 PARD3; partitioning defective protein 3
K06093 PARD6; partitioning defective protein 6
K06093 PARD6; partitioning defective protein 6
K18952 PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
K06069 PRKCI; atypical protein kinase C iota type [EC:2.7.11.13]
K06092 INADL; InaD-like protein
K06091 MPP5; MAGUK p55 subfamily member 5
K16819 AMOT; angiomotin
K16687 YAP1; transcriptional coactivator YAP1
K16820 WWTR1; WW domain-containing transcription regulator protein 1
K05689 CDH1; cadherin 1, type 1, E-cadherin
K16682 AJUBA; LIM domain-containing protein
K16682 AJUBA; LIM domain-containing protein
K16682 AJUBA; LIM domain-containing protein
K16684 NF2; merlin
K16685 WWC1; protein KIBRA
K16821 FRMD1; FERM domain-containing protein 1
K16822 FRMD6; FERM domain-containing protein 6
K16686 SAV1; scaffold protein salvador
K04412 STK3; serine/threonine kinase 3
K09854 RASSF6; Ras association domain-containing protein 6
K09850 RASSF1; Ras association domain-containing protein 1
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K08791 LATS1_2; serine/threonine-protein kinase LATS1/2 [EC:2.7.11.1]
K08791 LATS1_2; serine/threonine-protein kinase LATS1/2 [EC:2.7.11.1]
K06685 MOB1; MOB kinase activator 1
K06685 MOB1; MOB kinase activator 1
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K16823 TP53BP2; apoptosis-stimulating of p53 protein 2
K06094 LLGL; lethal(2) giant larvae protein
K06094 LLGL; lethal(2) giant larvae protein
K16175 SCRIB; protein scribble
K12076 DLG1; disks large protein 1
K12075 DLG2; discs large protein 2
K21098 DLG3; discs large protein 3
K11828 DLG4; discs large protein 4
K24050 DLG5; discs large protein 5
K08959 CSNK1D; casein kinase 1, delta [EC:2.7.11.1]
K08960 CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]
K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
K10148 TP73; tumor protein p73
K10132 BBC3; Bcl-2-binding component 3
K09448 TEAD; transcriptional enhancer factor
K09448 TEAD; transcriptional enhancer factor
K09448 TEAD; transcriptional enhancer factor
K09448 TEAD; transcriptional enhancer factor
K09448 TEAD; transcriptional enhancer factor
K06827 CTGF; connective tissue growth factor (insulin-like growth factor-binding protein 8)
K16798 GLI2; zinc finger protein GLI2
K09782 AREG; amphiregulin
K08731 BIRC5; baculoviral IAP repeat-containing protein 5
K16144 AFP; alpha-fetoprotein
K06464 ITGB2; integrin beta 2
K18496 FGF1; fibroblast growth factor 1
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K19631 SMAD7; mothers against decapentaplegic homolog 7
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K03982 SERPINE1; plasminogen activator inhibitor 1
K21283 BMP2; bone morphogenetic protein 2
K04662 BMP4; bone morphogenetic protein 4
K04663 BMP5; bone morphogenetic protein 5
K16620 BMP6; bone morphogenetic protein 6
K16621 BMP7; bone morphogenetic protein 7
K16622 BMP8; bone morphogenetic protein 8
K16622 BMP8; bone morphogenetic protein 8
K04664 GDF5; growth differentiation factor 5
K20012 GDF6; growth differentiation factor 6
K20013 GDF7; growth differentiation factor 7
K04665 AMH; anti-mullerian hormone
K04673 BMPR1A; bone morphogenetic protein receptor type-1A [EC:2.7.11.30]
K13578 BMPR1B; bone morphogenetic protein receptor type-1B [EC:2.7.11.30]
K04671 BMPR2; bone morphogenetic protein receptor type-2 [EC:2.7.11.30]
K04676 SMAD1; mothers against decapentaplegic homolog 1
K04680 ID1; DNA-binding protein inhibitor ID1
K17693 ID2; DNA-binding protein inhibitor ID2
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7; frizzled 1/7
K02432 FZD1_7; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4; frizzled 4
K02375 FZD5_8; frizzled 5/8
K02375 FZD5_8; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10; frizzled 9/10
K02842 FZD9_10; frizzled 9/10
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K06630 YWHAE; 14-3-3 protein epsilon
K06630 YWHAE; 14-3-3 protein epsilon
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02105 CTNNB1; catenin beta 1
K02085 APC; adenomatosis polyposis coli protein
K02085 APC; adenomatosis polyposis coli protein
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K03213 NKD; naked cuticle
K03213 NKD; naked cuticle
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K16796 SOX2; transcription factor SOX2 (SOX group B)
K05706 SNAI2; snail 2
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K05692 ACTB_G1; actin beta/gamma 1
K05692 ACTB_G1; actin beta/gamma 1
K05691 CTNNA; catenin alpha
K05691 CTNNA; catenin alpha
K05691 CTNNA; catenin alpha
|
04391 Hippo signaling pathway - fly
|
04392 Hippo signaling pathway - multiple species [PATH:nle04392]
|
100606055 DCHS2; protocadherin-23
100601098 DCHS1; protocadherin-16 isoform X1
100595864 FAT4; protocadherin Fat 4 isoform X2
100607246 casein kinase I isoform X1
100599082 NF2; merlin isoform X1
100603663 WWC1; protein KIBRA isoform X1
100592876 FRMD1; FERM domain-containing protein 1
100607824 FRMD6; FERM domain-containing protein 6 isoform X2
100592827 RASSF1; ras association domain-containing protein 1 isoform X1
100585609 RASSF6; ras association domain-containing protein 6 isoform X1
100587096 STK3; serine/threonine-protein kinase 3
100603888 SAV1; protein salvador homolog 1 isoform X1
100599863 LATS1; serine/threonine-protein kinase LATS1 isoform X1
100594910 LATS2; serine/threonine-protein kinase LATS2
100584060 MOB1A; MOB kinase activator 1A isoform X1
100579837 MOB1B; MOB kinase activator 1B
100605716 LIMD1; LIM domain-containing protein 1
100590380 WTIP; Wilms tumor protein 1-interacting protein isoform X1
100587239 AJUBA; LIM domain-containing protein ajuba
100607618 YAP1; transcriptional coactivator YAP1 isoform X12
100592028 WWTR1; WW domain-containing transcription regulator protein 1
100598874 TEAD3; transcriptional enhancer factor TEF-5
100597345 TEAD2; transcriptional enhancer factor TEF-4 isoform X1
100600190 TEAD1; transcriptional enhancer factor TEF-1 isoform X3
100601311 TEAD4; transcriptional enhancer factor TEF-3 isoform X1
115832281 chromatin-remodeling ATPase INO80-like
100582743 RASSF4; ras association domain-containing protein 4
100589906 RASSF2; ras association domain-containing protein 2
100588769 PAK1; serine/threonine-protein kinase PAK 1 isoform X2
|
K16507 DCHS1_2; protocadherin-16/23
K16507 DCHS1_2; protocadherin-16/23
K16669 FAT4; protocadherin Fat 4
K08960 CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]
K16684 NF2; merlin
K16685 WWC1; protein KIBRA
K16821 FRMD1; FERM domain-containing protein 1
K16822 FRMD6; FERM domain-containing protein 6
K09850 RASSF1; Ras association domain-containing protein 1
K09854 RASSF6; Ras association domain-containing protein 6
K04412 STK3; serine/threonine kinase 3
K16686 SAV1; scaffold protein salvador
K08791 LATS1_2; serine/threonine-protein kinase LATS1/2 [EC:2.7.11.1]
K08791 LATS1_2; serine/threonine-protein kinase LATS1/2 [EC:2.7.11.1]
K06685 MOB1; MOB kinase activator 1
K06685 MOB1; MOB kinase activator 1
K16682 AJUBA; LIM domain-containing protein
K16682 AJUBA; LIM domain-containing protein
K16682 AJUBA; LIM domain-containing protein
K16687 YAP1; transcriptional coactivator YAP1
K16820 WWTR1; WW domain-containing transcription regulator protein 1
K09448 TEAD; transcriptional enhancer factor
K09448 TEAD; transcriptional enhancer factor
K09448 TEAD; transcriptional enhancer factor
K09448 TEAD; transcriptional enhancer factor
K09448 TEAD; transcriptional enhancer factor
K09851 RASSF2_4; Ras association domain-containing protein 2/4
K09851 RASSF2_4; Ras association domain-containing protein 2/4
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
|
04370 VEGF signaling pathway [PATH:nle04370]
|
04371 Apelin signaling pathway [PATH:nle04371]
|
04630 JAK-STAT signaling pathway [PATH:nle04630]
|
04064 NF-kappa B signaling pathway [PATH:nle04064]
|
04668 TNF signaling pathway [PATH:nle04668]
|
04066 HIF-1 signaling pathway [PATH:nle04066]
|
04068 FoxO signaling pathway [PATH:nle04068]
|
04020 Calcium signaling pathway [PATH:nle04020]
|
04070 Phosphatidylinositol signaling system [PATH:nle04070]
|
04072 Phospholipase D signaling pathway [PATH:nle04072]
|
04071 Sphingolipid signaling pathway [PATH:nle04071]
|
04024 cAMP signaling pathway [PATH:nle04024]
|
04022 cGMP-PKG signaling pathway [PATH:nle04022]
|
04151 PI3K-Akt signaling pathway [PATH:nle04151]
|
04152 AMPK signaling pathway [PATH:nle04152]
|
04150 mTOR signaling pathway [PATH:nle04150]
|
04075 Plant hormone signal transduction
|
|
|
09133 Signaling molecules and interaction
|
|
|
09140 Cellular Processes
|
|
|
09150 Organismal Systems
|
|
|
09160 Human Diseases
|
|
|
09161 Cancer: overview
|
05200 Pathways in cancer [PATH:nle05200]
|
100583619 DCC; netrin receptor DCC
100585064 CASP3; caspase-3 isoform X3
100597173 CASP9; caspase-9 isoform X1
100599415 APPL1; DCC-interacting protein 13-alpha isoform X1
100596627 CDH1; cadherin-1 isoform X1
100583002 CTNNB1; catenin beta-1 isoform X1
100606736 CTNNA3; catenin alpha-3 isoform X1
100599144 CTNNA2; catenin alpha-2 isoform X5
100593453 CTNNA1; catenin alpha-1 isoform X1
101179424 AXIN1; axin-1 isoform X1
100589482 AXIN2; axin-2 isoform X1
100602025 APC2; adenomatous polyposis coli protein 2 isoform X1
100585467 APC; adenomatous polyposis coli protein isoform X3
100606885 GSK3B; glycogen synthase kinase-3 beta isoform X1
100595737 TCF7; LOW QUALITY PROTEIN: transcription factor 7
100601518 TCF7L1; transcription factor 7-like 1
100605701 TCF7L2; transcription factor 7-like 2 isoform X1
100593051 LEF1; lymphoid enhancer-binding factor 1 isoform X3
100598415 BIRC5; baculoviral IAP repeat-containing protein 5 isoform X1
100589322 MYC; myc proto-oncogene protein
100605736 CCND1; G1/S-specific cyclin-D1
100587307 WNT1; proto-oncogene Wnt-1
100607954 WNT2B; protein Wnt-2b isoform X2
100600353 WNT2; protein Wnt-2
100606846 WNT3A; protein Wnt-3a isoform X2
100599381 WNT3; proto-oncogene Wnt-3
100604353 WNT4; protein Wnt-4 isoform X1
100602014 WNT5A; protein Wnt-5a
100596686 WNT5B; protein Wnt-5b
100606818 WNT6; protein Wnt-6
100579580 WNT7B; protein Wnt-7b isoform X1
100593900 WNT7A; protein Wnt-7a
100586052 WNT8A; protein Wnt-8a isoform X2
100603238 WNT8B; protein Wnt-8b
100606502 WNT9A; protein Wnt-9a
100602760 WNT9B; protein Wnt-9b isoform X1
100607164 WNT10A; protein Wnt-10a
100587640 WNT10B; protein Wnt-10b
100594864 WNT11; protein Wnt-11
100605294 WNT16; protein Wnt-16 isoform X1
100597685 FZD7; frizzled-7
100605346 FZD1; frizzled-1
100580071 FZD2; frizzled-2
100589994 FZD3; frizzled-3
100588311 FZD4; frizzled-4
100589091 FZD5; frizzled-5
100593717 FZD8; frizzled-8
100603705 FZD6; frizzled-6
100607762 FZD10; frizzled-10
100592375 FZD9; frizzled-9
100586389 LRP6; low-density lipoprotein receptor-related protein 6
100588313 LRP5; low-density lipoprotein receptor-related protein 5
100585595 DVL2; segment polarity protein dishevelled homolog DVL-2
100583216 DVL3; segment polarity protein dishevelled homolog DVL-3
100593186 DVL1; segment polarity protein dishevelled homolog DVL-1 isoform X1
115834222 FRAT1; proto-oncogene FRAT1
100584425 FRAT2; GSK-3-binding protein FRAT2
100595467 F2; prothrombin
100605443 AGT; angiotensinogen
100607663 F2R; proteinase-activated receptor 1
100597937 F2RL3; proteinase-activated receptor 4
100589911 LPAR1; lysophosphatidic acid receptor 1
100587344 LPAR2; lysophosphatidic acid receptor 2 isoform X1
100590490 LPAR3; lysophosphatidic acid receptor 3 isoform X1
100588179 LPAR4; lysophosphatidic acid receptor 4
100586980 LPAR5; lysophosphatidic acid receptor 5
100588296 LPAR6; lysophosphatidic acid receptor 6
100603931 AGTR1; type-1 angiotensin II receptor isoform X3
100591916 GNA12; guanine nucleotide-binding protein subunit alpha-12
100589821 GNA13; guanine nucleotide-binding protein subunit alpha-13
100602658 ARHGEF12; rho guanine nucleotide exchange factor 12 isoform X4
100587231 ARHGEF11; rho guanine nucleotide exchange factor 11 isoform X1
100581841 ARHGEF1; rho guanine nucleotide exchange factor 1 isoform X1
100583767 PLEKHG5; pleckstrin homology domain-containing family G member 5 isoform X1
100607291 RHOA; transforming protein RhoA
100586590 ROCK1; rho-associated protein kinase 1
100585294 ROCK2; rho-associated protein kinase 2
100580964 CXCL12; stromal cell-derived factor 1 isoform X2
100604120 CXCR4; C-X-C chemokine receptor type 4
100588993 GNAI2; guanine nucleotide-binding protein G(i) subunit alpha-2 isoform X1
100583621 GNAI3; guanine nucleotide-binding protein G(i) subunit alpha
100604896 GNAI1; guanine nucleotide-binding protein G(i) subunit alpha-1 isoform X2
100606044 PTGER1; prostaglandin E2 receptor EP1 subtype
100581272 PTGER2; prostaglandin E2 receptor EP2 subtype
100593534 PTGER3; prostaglandin E2 receptor EP3 subtype isoform X3
100594164 PTGER4; prostaglandin E2 receptor EP4 subtype
101176289 GNAS; guanine nucleotide-binding protein G(s) subunit alpha isoform X7
115830355 neuroendocrine secretory protein 55
100595636 ADCY1; adenylate cyclase type 1
100600367 ADCY2; adenylate cyclase type 2
100586735 ADCY3; adenylate cyclase type 3 isoform X2
100603282 ADCY4; adenylate cyclase type 4 isoform X1
100580455 ADCY5; adenylate cyclase type 5 isoform X1
100589304 ADCY6; adenylate cyclase type 6
100587036 ADCY7; adenylate cyclase type 7
100592592 ADCY8; adenylate cyclase type 8 isoform X1
100599484 ADCY9; adenylate cyclase type 9 isoform X1
100583577 PRKACB; cAMP-dependent protein kinase catalytic subunit beta isoform X8
100579779 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha
100607741 PRKACG; LOW QUALITY PROTEIN: cAMP-dependent protein kinase catalytic subunit gamma
100583137 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
100590367 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 isoform X1
100596905 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
100589215 GNB4; guanine nucleotide-binding protein subunit beta-4
100594371 GNB5; guanine nucleotide-binding protein subunit beta-5 isoform X1
100579945 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
100579986 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
100591313 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
100586578 guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
115837666 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
115830866 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
115833531 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
115834702 guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10-like
100581702 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
100593358 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
100584569 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
115836971 GNG14; LOW QUALITY PROTEIN: putative guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-14
115831194 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
115834220 guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
100592009 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
115833576 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
100598507 COL4A4; collagen alpha-4(IV) chain
100587255 COL4A6; collagen alpha-6(IV) chain isoform X3
100584285 COL4A2; collagen alpha-2(IV) chain
100603791 COL4A1; collagen alpha-1(IV) chain isoform X1
100588259 COL4A5; collagen alpha-5(IV) chain
100598848 COL4A3; collagen alpha-3(IV) chain
100591959 LAMA1; laminin subunit alpha-1
100583654 LAMA2; laminin subunit alpha-2
100601935 LAMA3; laminin subunit alpha-3 isoform X1
100581144 LAMA5; laminin subunit alpha-5 isoform X1
100587786 LAMA4; laminin subunit alpha-4
100581721 LAMB1; laminin subunit beta-1
100591482 LAMB2; laminin subunit beta-2 isoform X1
100593136 LAMB3; laminin subunit beta-3
100581377 LAMB4; laminin subunit beta-4 isoform X1
100607126 LAMC1; laminin subunit gamma-1
100581925 LAMC2; laminin subunit gamma-2
100602023 LAMC3; laminin subunit gamma-3
100601303 FN1; fibronectin isoform X2
100588661 ITGA2; integrin alpha-2 isoform X1
100601385 ITGA2B; integrin alpha-IIb
100596503 ITGA3; integrin alpha-3 isoform X1
100600735 ITGA6; integrin alpha-6 isoform X2
100604485 ITGAV; integrin alpha-V isoform X1
100595108 ITGB1; integrin beta-1
100588218 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
100580872 PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1
100584384 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1
100605788 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1
100591270 PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1
100599301 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
100605147 PTEN; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
100605136 NKX3-1; homeobox protein Nkx-3.1 isoform X1
100604331 AKT3; RAC-gamma serine/threonine-protein kinase isoform X1
100587864 AKT2; RAC-beta serine/threonine-protein kinase isoform X1
100587109 AKT1; RAC-alpha serine/threonine-protein kinase
100596225 CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1
100588081 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1
100603768 IKBKG; NF-kappa-B essential modulator isoform X1
100599351 NFKBIA; NF-kappa-B inhibitor alpha
100581655 NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1
100590797 NFKB2; nuclear factor NF-kappa-B p100 subunit isoform X2
100588439 RELA; transcription factor p65
100591090 PTGS2; prostaglandin G/H synthase 2
100589003 NOS2; nitric oxide synthase, inducible
100599011 BCL2; apoptosis regulator Bcl-2
100579740 BIRC3; baculoviral IAP repeat-containing protein 3
100580307 BIRC2; baculoviral IAP repeat-containing protein 2
100597865 XIAP; E3 ubiquitin-protein ligase XIAP isoform X4
100586363 BIRC7; baculoviral IAP repeat-containing protein 7 isoform X1
100595330 BCL2L1; bcl-2-like protein 1
100605879 TRAF1; TNF receptor-associated factor 1 isoform X1
100590721 TRAF2; TNF receptor-associated factor 2 isoform X2
100606382 TRAF3; TNF receptor-associated factor 3 isoform X1
100607896 TRAF4; TNF receptor-associated factor 4 isoform X1
100601779 TRAF5; TNF receptor-associated factor 5 isoform X1
100595327 TRAF6; TNF receptor-associated factor 6 isoform X1
100594291 MTOR; serine/threonine-protein kinase mTOR isoform X1
100606492 RPS6KB2; ribosomal protein S6 kinase beta-2 isoform X1
100593862 RPS6KB1; ribosomal protein S6 kinase beta-1 isoform X1
101178725 BAD; bcl2-associated agonist of cell death
100594615 FOXO1; forkhead box protein O1
100601465 MDM2; E3 ubiquitin-protein ligase Mdm2 isoform X2
100583326 TP53; cellular tumor antigen p53
100589956 CDKN1B; cyclin-dependent kinase inhibitor 1B
100599083 CDKN1A; cyclin-dependent kinase inhibitor 1
100594695 BCR; breakpoint cluster region protein isoform X1
100601002 ABL1; tyrosine-protein kinase ABL1 isoform X1
100595820 CRKL; crk-like protein
100601245 CRK; adapter molecule crk isoform X1
100607272 CBL; E3 ubiquitin-protein ligase CBL
100602815 signal transducer and activator of transcription 5A isoform X1
100602489 signal transducer and activator of transcription 5B isoform X1
100580787 PIM1; serine/threonine-protein kinase pim-1
100603036 PIM2; serine/threonine-protein kinase pim-2
100597381 KNG1; kininogen-1 isoform X2
100579923 EDN1; endothelin-1
100599756 BDKRB1; B1 bradykinin receptor
100599411 BDKRB2; B2 bradykinin receptor
100582894 EDNRA; endothelin-1 receptor isoform X1
100584780 EDNRB; endothelin receptor type B
100594473 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
100584446 GNA11; guanine nucleotide-binding protein subunit alpha-11
100597115 PLCB1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X1
100600507 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X3
100606558 PLCB2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X1
100600865 PLCB3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3
100591651 PRKCA; protein kinase C alpha type isoform X1
100590939 PRKCB; protein kinase C beta type isoform X2
100601464 PRKCG; protein kinase C gamma type
100591126 IL2; interleukin-2
100593178 IL3; interleukin-3
100597165 IL4; interleukin-4 isoform X1
100597846 IL5; interleukin-5
100586527 IL6; interleukin-6 isoform X2
100606680 IL7; interleukin-7 isoform X1
100603245 IL12A; interleukin-12 subunit alpha isoform X1
100579267 interleukin-12 subunit beta
115837257 interleukin-12 subunit beta-like
100598534 IL13; interleukin-13 isoform X1
100598291 IL15; interleukin-15 isoform X1
100586740 IL23A; interleukin-23 subunit alpha
100607433 EPO; erythropoietin isoform X1
100597957 interferon alpha-10-like
100596272 IFNA6; interferon alpha-6
100595254 IFNA8; interferon alpha-8
100597288 interferon alpha-14
100596946 interferon alpha-5
100598307 interferon alpha-10
100595932 interferon alpha-1/13
100594907 interferon alpha-1/13
100597620 interferon alpha-4
100595585 IFNA2; interferon alpha-2
100583022 IFNG; interferon gamma
100582107 IL2RA; interleukin-2 receptor subunit alpha isoform X1
100581366 IL2RB; interleukin-2 receptor subunit beta
100585758 IL2RG; cytokine receptor common subunit gamma isoform X1
100606206 IL4R; interleukin-4 receptor subunit alpha isoform X1
100594820 CSF2RB; cytokine receptor common subunit beta isoform X2
100584044 IL5RA; interleukin-5 receptor subunit alpha isoform X5
100604063 IL6R; interleukin-6 receptor subunit alpha isoform X1
100581824 IL6ST; interleukin-6 receptor subunit beta isoform X1
100583768 IL7R; interleukin-7 receptor subunit alpha
100605040 IL12RB1; interleukin-12 receptor subunit beta-1 isoform X1
100582797 IL12RB2; interleukin-12 receptor subunit beta-2 isoform X1
100579912 IL13RA1; interleukin-13 receptor subunit alpha-1
100603939 IL15RA; interleukin-15 receptor subunit alpha
100582454 IL23R; interleukin-23 receptor
100593505 EPOR; erythropoietin receptor
100583382 IFNAR1; interferon alpha/beta receptor 1
100599809 IFNAR2; interferon alpha/beta receptor 2 isoform X1
100598615 IFNGR1; interferon gamma receptor 1 isoform X1
105738709 IFNGR2; interferon gamma receptor 2
100595819 EML4; echinoderm microtubule-associated protein-like 4 isoform X1
100593886 ALK; ALK tyrosine kinase receptor
100584529 RASGRP1; RAS guanyl-releasing protein 1
100603817 RASGRP2; RAS guanyl-releasing protein 2 isoform X2
100603635 RASGRP3; ras guanyl-releasing protein 3
100590994 RASGRP4; RAS guanyl-releasing protein 4 isoform X2
100588162 JAK1; tyrosine-protein kinase JAK1 isoform X1
100588880 JAK2; tyrosine-protein kinase JAK2 isoform X1
100603367 tyrosine-protein kinase JAK3 isoform X1
100598877 STAT3; signal transducer and activator of transcription 3 isoform X1
100596344 STAT1; signal transducer and activator of transcription 1-alpha/beta
100585171 STAT2; signal transducer and activator of transcription 2 isoform X1
100596678 STAT4; signal transducer and activator of transcription 4
100602651 STAT6; signal transducer and activator of transcription 6
100601396 VEGFA; vascular endothelial growth factor A isoform X1
100599288 VEGFB; vascular endothelial growth factor B isoform X2
100600228 PGF; placenta growth factor isoform X1
100601827 VEGFD; vascular endothelial growth factor D
100595914 VEGFC; vascular endothelial growth factor C
100607585 TGFA; protransforming growth factor alpha isoform X3
100588963 EGF; pro-epidermal growth factor isoform X1
100597255 EGFR; epidermal growth factor receptor isoform X1
100601700 ERBB2; receptor tyrosine-protein kinase erbB-2 isoform X1
100583683 PDGFA; platelet-derived growth factor subunit A isoform X6
100586714 PDGFB; platelet-derived growth factor subunit B
100603207 PDGFRA; platelet-derived growth factor receptor alpha
100597894 PDGFRB; platelet-derived growth factor receptor beta
100595306 IGF1; insulin-like growth factor I isoform X3
100585821 IGF2; insulin-like growth factor II isoform X2
100593288 IGF1R; insulin-like growth factor 1 receptor isoform X1
100587810 KITLG; kit ligand
100603893 KIT; mast/stem cell growth factor receptor Kit isoform X3
100589184 FLT3; receptor-type tyrosine-protein kinase FLT3 isoform X1
100586296 HGF; hepatocyte growth factor isoform X1
100597172 MET; hepatocyte growth factor receptor isoform X3
100603200 FGF1; LOW QUALITY PROTEIN: fibroblast growth factor 1
100593123 FGF2; fibroblast growth factor 2 isoform X1
100588427 FGF18; fibroblast growth factor 18
100598611 FGF8; fibroblast growth factor 8 isoform X1
100587475 FGF4; fibroblast growth factor 4
100587808 FGF3; fibroblast growth factor 3
100603249 FGF20; fibroblast growth factor 20
100601992 FGF9; fibroblast growth factor 9
100580620 FGF7; fibroblast growth factor 7
100605698 fibroblast growth factor 6
100590822 FGF10; fibroblast growth factor 10
100591900 FGF17; fibroblast growth factor 17 isoform X1
100585623 FGF16; fibroblast growth factor 16
100583276 FGF5; fibroblast growth factor 5 isoform X1
100598059 FGF22; fibroblast growth factor 22 isoform X2
100606867 FGF19; fibroblast growth factor 19
100590773 FGF21; fibroblast growth factor 21
100605361 FGF23; fibroblast growth factor 23
100602423 FGFR1; fibroblast growth factor receptor 1 isoform X1
100598157 FGFR2; fibroblast growth factor receptor 2 isoform X1
100591839 FGFR3; fibroblast growth factor receptor 3 isoform X1
100582351 FGFR4; fibroblast growth factor receptor 4
100588468 GRB2; growth factor receptor-bound protein 2
100590165 SOS1; son of sevenless homolog 1 isoform X1
100600495 SOS2; LOW QUALITY PROTEIN: son of sevenless homolog 2
100595274 HRAS; GTPase HRas isoform X1
100593773 KRAS; GTPase KRas isoform X1
100592103 NRAS; GTPase NRas
100595311 ARAF; serine/threonine-protein kinase A-Raf
100582848 BRAF; serine/threonine-protein kinase B-raf isoform X2
100582599 RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X1
100579506 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1
100591827 MAP2K2; dual specificity mitogen-activated protein kinase kinase 2
100600574 MAPK1; mitogen-activated protein kinase 1
100584480 MAPK3; mitogen-activated protein kinase 3
100586501 JUN; transcription factor AP-1
100585899 FOS; proto-oncogene c-Fos
100606580 ETS1; protein C-ets-1 isoform X2
100582292 MMP1; interstitial collagenase isoform X1
100597186 MMP2; 72 kDa type IV collagenase isoform X1
100587873 MMP9; matrix metalloproteinase-9
100586157 CXCL8; interleukin-8
100594967 CDK4; cyclin-dependent kinase 4
100597734 RPS6KA5; ribosomal protein S6 kinase alpha-5 isoform X1
100602103 RET; proto-oncogene tyrosine-protein kinase receptor Ret isoform X1
100602694 CCDC6; coiled-coil domain-containing protein 6
100587232 NCOA4; nuclear receptor coactivator 4 isoform X1
100585466 NTRK1; high affinity nerve growth factor receptor
100600342 TPM3; tropomyosin alpha-3 chain isoform X8
100598772 tropomyosin alpha-3 chain-like isoform X1
100583608 TPR; nucleoprotein TPR isoform X1
100591399 TFG; protein TFG isoform X2
100592827 RASSF1; ras association domain-containing protein 1 isoform X1
100607511 RASSF5; ras association domain-containing protein 5 isoform X1
100599164 STK4; serine/threonine-protein kinase 4
100590142 DAPK3; death-associated protein kinase 3
100603623 DAPK1; death-associated protein kinase 1 isoform X1
100598470 DAPK2; death-associated protein kinase 2 isoform X2
100591458 PLCG1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1
100604145 PLCG2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
100596002 ELK1; ETS domain-containing protein Elk-1
100586234 calmodulin-like
100582584 CALM2; calmodulin-2
100584686 CALML6; calmodulin-like protein 6
100595594 CALM1; calmodulin-1
100607765 CALML3; calmodulin-like protein 3
100602246 CALM3; calmodulin-3
100588287 CALML4; calmodulin-like protein 4 isoform X1
100603253 CALML5; calmodulin-like protein 5
100597007 CAMK2G; calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X1
100600165 CAMK2A; calcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1
100591995 CAMK2B; calcium/calmodulin-dependent protein kinase type II subunit beta isoform X1
100580290 CAMK2D; calcium/calmodulin-dependent protein kinase type II subunit delta isoform X30
100589231 RALGDS; ral guanine nucleotide dissociation stimulator isoform X1
100579487 LOW QUALITY PROTEIN: ral-GDS-related protein
115835869 LOW QUALITY PROTEIN: ral-GDS-related protein-like
100603441 RALA; ras-related protein Ral-A
100593053 RALB; ras-related protein Ral-B
100600679 RALBP1; ralA-binding protein 1
100605245 CDC42; cell division control protein 42 homolog isoform X1
100604516 RAC1; ras-related C3 botulinum toxin substrate 1
100598232 RAC2; ras-related C3 botulinum toxin substrate 2
100602123 RAC3; ras-related C3 botulinum toxin substrate 3 isoform X3
100605600 PLD1; phospholipase D1
100601695 PLD2; phospholipase D2 isoform X1
100581677 MAPK9; mitogen-activated protein kinase 9 isoform X1
100605285 MAPK8; mitogen-activated protein kinase 8 isoform X1
100602081 MAPK10; mitogen-activated protein kinase 10 isoform X2
100591164 PAX8; paired box protein Pax-8 isoform X1
100581046 PPARG; peroxisome proliferator-activated receptor gamma isoform X1
100585339 RXRA; retinoic acid receptor RXR-alpha isoform X1
100580742 RXRB; retinoic acid receptor RXR-beta isoform X2
100592610 RXRG; retinoic acid receptor RXR-gamma
100596579 RARB; retinoic acid receptor beta isoform X2
100580202 ESR1; estrogen receptor isoform X2
100595169 ESR2; estrogen receptor beta isoform X1
100586410 NCOA1; nuclear receptor coactivator 1 isoform X1
100587426 NCOA3; nuclear receptor coactivator 3 isoform X7
100585963 SP1; transcription factor Sp1
100584681 PPARD; peroxisome proliferator-activated receptor delta
100591948 JUP; junction plakoglobin
100592350 ZBTB16; zinc finger and BTB domain-containing protein 16
100603497 RARA; retinoic acid receptor alpha isoform X1
100594705 CCNA1; cyclin-A1 isoform X3
105740029 CCNA2; cyclin-A2
100607016 PML; protein PML
100594110 RUNX1; runt-related transcription factor 1 isoform X1
100590085 RUNX1T1; LOW QUALITY PROTEIN: protein CBFA2T1
100580017 SPI1; transcription factor PU.1 isoform X2
100604930 CEBPA; CCAAT/enhancer-binding protein alpha
100596513 granulocyte-macrophage colony-stimulating factor receptor subunit alpha-like
100605652 granulocyte-macrophage colony-stimulating factor receptor subunit alpha isoform X1
100602399 LOW QUALITY PROTEIN: granulocyte-macrophage colony-stimulating factor receptor subunit alpha-like
115834049 granulocyte-macrophage colony-stimulating factor receptor subunit alpha-like
115834378 granulocyte-macrophage colony-stimulating factor receptor subunit alpha-like
100594510 CSF3R; granulocyte colony-stimulating factor receptor isoform X2
100598906 CSF1R; macrophage colony-stimulating factor 1 receptor isoform X1
100586796 CDKN2A; cyclin-dependent kinase inhibitor 2A isoform X1
100601097 E2F1; transcription factor E2F1
100583853 E2F2; transcription factor E2F2
100594018 E2F3; transcription factor E2F3 isoform X1
100601755 MAX; protein max isoform X2
100589356 ZBTB17; zinc finger and BTB domain-containing protein 17 isoform X1
100593298 CDKN2B; cyclin-dependent kinase 4 inhibitor B isoform X1
100602542 CDK6; cyclin-dependent kinase 6
100585770 CCND2; G1/S-specific cyclin-D2
100580170 CCND3; G1/S-specific cyclin-D3 isoform X1
100590950 CKS2; cyclin-dependent kinases regulatory subunit 2
100580794 CKS1B; cyclin-dependent kinases regulatory subunit 1
100596865 SKP1; S-phase kinase-associated protein 1
100580180 CUL1; cullin-1 isoform X1
100596079 RBX1; E3 ubiquitin-protein ligase RBX1 isoform X1
100586655 SKP2; S-phase kinase-associated protein 2 isoform X2
100592796 CDK2; cyclin-dependent kinase 2
100607751 CCNE1; G1/S-specific cyclin-E1
100602200 CCNE2; G1/S-specific cyclin-E2
100588629 RB1; retinoblastoma-associated protein
100593432 GADD45G; growth arrest and DNA damage-inducible protein GADD45 gamma
100583800 GADD45A; growth arrest and DNA damage-inducible protein GADD45 alpha
115830865 GADD45B; growth arrest and DNA damage-inducible protein GADD45 beta
100593013 BAX; apoptosis regulator BAX isoform X1
100588483 BAK1; bcl-2 homologous antagonist/killer isoform X1
100605065 DDB2; DNA damage-binding protein 2 isoform X1
100598341 POLK; DNA polymerase kappa isoform X1
101175959 TERT; telomerase reverse transcriptase isoform X1
100599577 MITF; microphthalmia-associated transcription factor isoform X1
100581386 TGFB1; transforming growth factor beta-1 proprotein isoform X2
100596183 TGFB2; transforming growth factor beta-2 proprotein isoform X1
100591391 TGFB3; transforming growth factor beta-3 proprotein
100592854 TGFBR1; TGF-beta receptor type-1 isoform X1
100606849 TGFBR2; TGF-beta receptor type-2 isoform X2
100589735 SMAD2; mothers against decapentaplegic homolog 2 isoform X1
100583279 SMAD3; mothers against decapentaplegic homolog 3 isoform X1
100599586 SMAD4; mothers against decapentaplegic homolog 4 isoform X1
100591579 MECOM; histone-lysine N-methyltransferase MECOM isoform X1
100601461 CTBP2; C-terminal-binding protein 2 isoform X1
100603170 CTBP1; C-terminal-binding protein 1 isoform X1
100591684 HDAC2; histone deacetylase 2 isoform X1
100591033 HDAC1; histone deacetylase 1 isoform X3
100593390 MLH1; DNA mismatch repair protein Mlh1 isoform X2
100580147 MSH2; DNA mismatch repair protein Msh2 isoform X1
100595600 MSH3; DNA mismatch repair protein Msh3 isoform X1
100593553 MSH6; DNA mismatch repair protein Msh6
100601625 BRCA2; breast cancer type 2 susceptibility protein
100584720 RAD51; DNA repair protein RAD51 homolog 1 isoform X1
100597719 FASLG; tumor necrosis factor ligand superfamily member 6 isoform X1
100580318 FAS; tumor necrosis factor receptor superfamily member 6 isoform X1
100607557 FADD; FAS-associated death domain protein
100586183 CASP8; caspase-8 isoform X1
100580571 BID; BH3-interacting domain death agonist
100593765 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
100588342 BBC3; bcl-2-binding component 3 isoform X1
100594069 BCL2L11; bcl-2-like protein 11 isoform X1
100603746 cytochrome c-like
100600457 cytochrome c-like
100580069 cytochrome c
100598207 cytochrome c-like
100599727 cytochrome c-like
101179576 cytochrome c-like
100604294 cytochrome c-like
100590369 APAF1; apoptotic protease-activating factor 1 isoform X1
100588449 KEAP1; kelch-like ECH-associated protein 1 isoform X1
100589990 NFE2L2; nuclear factor erythroid 2-related factor 2 isoform X3
100587046 HMOX1; heme oxygenase 1
100602948 NQO1; NAD(P)H dehydrogenase [quinone] 1
100604706 GSTO1; glutathione S-transferase omega-1
100606364 GSTO2; glutathione S-transferase omega-2
100583420 GSTA4; glutathione S-transferase A4
100584415 glutathione S-transferase A1 isoform X1
100583757 glutathione S-transferase A3 isoform X1
100584083 glutathione S-transferase A5
100606903 glutathione S-transferase omega-1-like isoform X2
100589494 glutathione S-transferase theta-2B
100590747 glutathione S-transferase theta-4
100597491 MGST2; microsomal glutathione S-transferase 2 isoform X2
100603656 MGST1; microsomal glutathione S-transferase 1
100582253 glutathione S-transferase theta-1 isoform X1
100588847 GSTM3; glutathione S-transferase mu 3
100586279 GSTM4; glutathione S-transferase Mu 4 isoform X1
100587851 GSTM1; glutathione S-transferase Mu 1 isoform X2
100587060 GSTM2; glutathione S-transferase Mu 2
100593636 MGST3; microsomal glutathione S-transferase 3
115830401 GSTM5; LOW QUALITY PROTEIN: glutathione S-transferase Mu 5
115835864 LOW QUALITY PROTEIN: glutathione S-transferase theta-3-like
100583601 glutathione S-transferase theta-4-like
100580544 glutathione S-transferase P
100600391 TXNRD1; thioredoxin reductase 1, cytoplasmic isoform X3
100594879 TXNRD3; thioredoxin reductase 3
100585816 TXNRD2; thioredoxin reductase 2, mitochondrial isoform X1
100600696 VHL; von Hippel-Lindau disease tumor suppressor isoform X2
100581166 elongin-C-like
100596876 ELOC; elongin-C isoform X1
100604447 elongin-B
100584170 ELOB; elongin-B
100593391 CUL2; cullin-2 isoform X1
100591967 EGLN3; egl nine homolog 3 isoform X1
100594374 EGLN1; egl nine homolog 1 isoform X1
100584172 EGLN2; egl nine homolog 2
100600492 FH; fumarate hydratase, mitochondrial isoform X1
100588621 HIF1A; hypoxia-inducible factor 1-alpha isoform X2
100606638 EPAS1; endothelial PAS domain-containing protein 1
100579793 ARNT; aryl hydrocarbon receptor nuclear translocator isoform X3
100589784 ARNT2; aryl hydrocarbon receptor nuclear translocator 2 isoform X1
100589381 EP300; histone acetyltransferase p300
100596998 CREBBP; CREB-binding protein isoform X1
100594511 SLC2A1; solute carrier family 2, facilitated glucose transporter member 1
100590989 JAG1; protein jagged-1
100588659 JAG2; protein jagged-2 isoform X1
100592674 DLL3; delta-like protein 3 isoform X2
100606767 DLL1; delta-like protein 1
100587621 DLL4; delta-like protein 4
100602494 NOTCH1; neurogenic locus notch homolog protein 1 isoform X1
100584613 NOTCH2; neurogenic locus notch homolog protein 2 isoform X1
100590691 NOTCH3; neurogenic locus notch homolog protein 3
100600732 NOTCH4; neurogenic locus notch homolog protein 4
100603131 HES1; transcription factor HES-1
115832989 HES5; transcription factor HES-5 isoform X1
100587093 HEY2; hairy/enhancer-of-split related with YRPW motif protein 2
100580851 HEY1; hairy/enhancer-of-split related with YRPW motif protein 1 isoform X2
100602780 HEYL; hairy/enhancer-of-split related with YRPW motif-like protein isoform X1
100582920 FLT4; vascular endothelial growth factor receptor 3
100582247 SHH; sonic hedgehog protein isoform X1
100581789 PTCH1; protein patched homolog 1 isoform X1
100585701 SMO; smoothened homolog isoform X1
100587965 KIF7; kinesin-like protein KIF7 isoform X1
100593147 SUFU; suppressor of fused homolog isoform X2
100599158 GLI1; zinc finger protein GLI1
100593982 GLI2; zinc finger protein GLI2
100589630 GLI3; transcriptional activator GLI3 isoform X1
100586297 BMP2; bone morphogenetic protein 2
100586277 BMP4; bone morphogenetic protein 4 isoform X1
100602907 HHIP; hedgehog-interacting protein
100591053 PTCH2; protein patched homolog 2 isoform X1
100598603 AR; androgen receptor isoform X1
100602573 heat shock protein HSP 90-alpha
100600046 HSP90AB1; heat shock protein HSP 90-beta
100603153 LOW QUALITY PROTEIN: endoplasmin-like
100599149 HSP90B1; endoplasmin
100585512 prostate-specific antigen isoform X1
|
K06765 DCC; deleted in colorectal carcinoma
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K08733 APPL1; DCC-interacting protein 13 alpha
K05689 CDH1; cadherin 1, type 1, E-cadherin
K02105 CTNNB1; catenin beta 1
K05691 CTNNA; catenin alpha
K05691 CTNNA; catenin alpha
K05691 CTNNA; catenin alpha
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02085 APC; adenomatosis polyposis coli protein
K02085 APC; adenomatosis polyposis coli protein
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K08731 BIRC5; baculoviral IAP repeat-containing protein 5
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; G1/S-specific cyclin-D1
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7; frizzled 1/7
K02432 FZD1_7; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4; frizzled 4
K02375 FZD5_8; frizzled 5/8
K02375 FZD5_8; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10; frizzled 9/10
K02842 FZD9_10; frizzled 9/10
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K03069 FRAT1; frequently rearranged in advanced T-cell lymphomas 1
K03096 FRAT2; frequently rearranged in advanced T-cell lymphomas 2
K01313 F2; coagulation factor II (thrombin) [EC:3.4.21.5]
K09821 AGT; angiotensinogen
K03914 F2R; coagulation factor II (thrombin) receptor
K04236 F2RL3; coagulation factor II (thrombin) receptor-like 3
K04289 LPAR1; lysophosphatidic acid receptor 1
K04291 LPAR2; lysophosphatidic acid receptor 2
K04294 LPAR3; lysophosphatidic acid receptor 3
K04275 LPAR4; lysophosphatidic acid receptor 4
K08390 LPAR5; lysophosphatidic acid receptor 5
K04273 LPAR6; lysophosphatidic acid receptor 6
K04166 AGTR1; angiotensin II receptor type 1
K04346 GNA12; guanine nucleotide-binding protein subunit alpha-12
K04639 GNA13; guanine nucleotide-binding protein subunit alpha-13
K07532 ARHGEF12; Rho guanine nucleotide exchange factor 12
K12331 ARHGEF11; Rho guanine nucleotide exchange factor 11
K12330 ARHGEF1; Rho guanine nucleotide exchange factor 1
K19464 PLEKHG5; pleckstrin homology domain-containing family G member 5
K04513 RHOA; Ras homolog gene family, member A
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K10031 CXCL12; C-X-C motif chemokine 12
K04189 CXCR4; C-X-C chemokine receptor type 4
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04258 PTGER1; prostaglandin E receptor 1
K04259 PTGER2; prostaglandin E receptor 2
K04260 PTGER3; prostaglandin E receptor 3
K04261 PTGER4; prostaglandin E receptor 4
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K05637 LAMA1_2; laminin, alpha 1/2
K05637 LAMA1_2; laminin, alpha 1/2
K06240 LAMA3_5; laminin, alpha 3/5
K06240 LAMA3_5; laminin, alpha 3/5
K06241 LAMA4; laminin, alpha 4
K05636 LAMB1; laminin, beta 1
K06243 LAMB2; laminin, beta 2
K06244 LAMB3; laminin, beta 3
K06245 LAMB4; laminin, beta 4
K05635 LAMC1; laminin, gamma 1
K06246 LAMC2; laminin, gamma 2
K06247 LAMC3; laminin, gamma 3
K05717 FN1; fibronectin 1
K06481 ITGA2; integrin alpha 2
K06476 ITGA2B; integrin alpha 2B
K06482 ITGA3; integrin alpha 3
K06485 ITGA6; integrin alpha 6
K06487 ITGAV; integrin alpha V
K05719 ITGB1; integrin beta 1
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K09348 NKX3-1; homeobox protein Nkx-3.1
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04469 NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
K04735 RELA; transcription factor p65
K11987 PTGS2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
K02161 BCL2; apoptosis regulator Bcl-2
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04725 XIAP; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K16061 BIRC7_8; baculoviral IAP repeat-containing protein 7/8
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K03172 TRAF1; TNF receptor-associated factor 1
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K03174 TRAF3; TNF receptor-associated factor 3
K09848 TRAF4; TNF receptor-associated factor 4
K09849 TRAF5; TNF receptor-associated factor 5
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K07201 FOXO1; forkhead box protein O1
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53; tumor protein p53
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K08878 BCR1; breakpoint cluster region protein [EC:2.7.11.1]
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K04438 CRK; C-crk adapter molecule crk
K04438 CRK; C-crk adapter molecule crk
K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K04702 PIM1; proto-oncogene serine/threonine-protein kinase Pim-1 [EC:2.7.11.1]
K08806 PIM2; proto-oncogene serine/threonine-protein kinase Pim-2 [EC:2.7.11.1]
K03898 KNG; kininogen
K16366 EDN1; endothelin-1
K03915 BDKRB1; bradykinin receptor B1
K03916 BDKRB2; bradykinin receptor B2
K04197 EDNRA; endothelin receptor type A
K04198 EDNRB; endothelin receptor type B
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K05429 IL2; interleukin 2
K04736 IL3; interleukin 3
K05430 IL4; interleukin 4
K05428 IL5; interleukin 5
K05405 IL6; interleukin 6
K05431 IL7; interleukin 7
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05425 IL12B; interleukin 12B
K05435 IL13; interleukin 13
K05433 IL15; interleukin 15
K05426 IL23A; interleukin 23 subunit alpha
K05437 EPO; erythropoietin
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K04687 IFNG; interferon gamma
K05068 IL2RA; interleukin 2 receptor alpha
K05069 IL2RB; interleukin 2 receptor beta
K05070 IL2RG; interleukin 2 receptor gamma
K05071 IL4R; interleukin 4 receptor
K04738 CSF2RB; cytokine receptor common subunit beta
K05067 IL5RA. CD125; interleukin 5 receptor alpha
K05055 IL6R; interleukin 6 receptor
K05060 IL6ST; interleukin 6 signal transducer
K05072 IL7R; interleukin 7 receptor
K05063 IL12RB1; interleukin 12 receptor beta-1
K05064 IL12RB2; interleukin 12 receptor beta-2
K05076 IL13RA1; interleukin 13 receptor alpha-1
K05074 IL15RA; interleukin 15 receptor alpha
K05065 IL23R; interleukin 23 receptor
K05079 EPOR; erythropoietin receptor
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K05132 IFNGR1; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K15420 EML4; echinoderm microtubule-associated protein-like 4
K05119 ALK; anaplastic lymphoma kinase [EC:2.7.10.1]
K04350 RASGRP1; RAS guanyl-releasing protein 1
K12361 RASGRP2; RAS guanyl-releasing protein 2
K12362 RASGRP3; RAS guanyl-releasing protein 3
K12363 RASGRP4; RAS guanyl-releasing protein 4
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K11222 STAT4; signal transducer and activator of transcription 4
K11225 STAT6; signal transducer and activator of transcription 6
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K16859 PGF; placenta growth factor
K05449 VEGFC_D; vascular endothelial growth factor C/D
K05449 VEGFC_D; vascular endothelial growth factor C/D
K08774 TGFA; transforming growth factor, alpha
K04357 EGF; epidermal growth factor
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K04363 PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05459 IGF1; insulin-like growth factor 1
K13769 IGF2; insulin-like growth factor 2
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K05461 KITLG; KIT ligand
K05091 KIT; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K05092 FLT3; fms-related tyrosine kinase 3 [EC:2.7.10.1]
K05460 HGF; hepatocyte growth factor
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K04362 FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04379 FOS; proto-oncogene protein c-fos
K02678 ETS1; C-ets-1
K01388 MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
K01398 MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K10030 IL8; interleukin 8
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K04445 RPS6KA5; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
K05126 RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
K09288 CCDC6; coiled-coil domain-containing protein 6
K09289 NCOA4; nuclear receptor coactivator 4
K03176 NTRK1; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K09290 TPM3; tropomyosin 3
K09290 TPM3; tropomyosin 3
K09291 TPR; nucleoprotein TPR
K09292 TFG; protein TFG
K09850 RASSF1; Ras association domain-containing protein 1
K08015 RASSF5; Ras association domain-containing protein 5
K04411 STK4; serine/threonine kinase 4
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K04375 ELK1; ETS domain-containing protein Elk-1
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K07834 RALA; Ras-related protein Ral-A
K07835 RALB; Ras-related protein Ral-B
K08773 RALBP1; RalA-binding protein 1
K04393 CDC42; cell division control protein 42
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K09293 PAX8; paired box protein 8
K08530 NR1C3; peroxisome proliferator-activated receptor gamma
K08524 RXRA; retinoid X receptor alpha
K08525 RXRB; retinoid X receptor beta
K08526 RXRG; retinoid X receptor gamma
K08528 RARB; retinoic acid receptor beta
K08550 ESR1; estrogen receptor alpha
K08551 ESR2; estrogen receptor beta
K09101 NCOA1; nuclear receptor coactivator 1 [EC:2.3.1.48]
K11256 NCOA3; nuclear receptor coactivator 3 [EC:2.3.1.48]
K04684 SP1; transcription factor Sp1
K04504 NR1C2; peroxisome proliferator-activated receptor delta
K10056 JUP; junction plakoglobin
K10055 ZBTB16; zinc finger and BTB domain-containing protein 16
K08527 RARA; retinoic acid receptor alpha
K06627 CCNA; cyclin-A
K06627 CCNA; cyclin-A
K10054 PML; probable transcription factor PML
K08367 RUNX1; runt-related transcription factor 1
K10053 RUNX1T1; CBFA2/RNUX1 translocation partner 1
K09438 SPI1; transcription factor PU.1
K09055 CEBPA; CCAAT/enhancer binding protein (C/EBP), alpha
K05066 CSF2RA; granulocyte-macrophage colony-stimulating factor receptor alpha
K05066 CSF2RA; granulocyte-macrophage colony-stimulating factor receptor alpha
K05066 CSF2RA; granulocyte-macrophage colony-stimulating factor receptor alpha
K05066 CSF2RA; granulocyte-macrophage colony-stimulating factor receptor alpha
K05066 CSF2RA; granulocyte-macrophage colony-stimulating factor receptor alpha
K05061 CSF3R; granulocyte colony-stimulating factor receptor
K05090 CSF1R; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04453 MAX; Max protein
K10500 ZBTB17; zinc finger and BTB domain-containing protein 17
K04685 CDKN2B; cyclin-dependent kinase inhibitor 2B
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K02219 CKS1; cyclin-dependent kinase regulatory subunit CKS1
K02219 CKS1; cyclin-dependent kinase regulatory subunit CKS1
K03094 SKP1; S-phase kinase-associated protein 1
K03347 CUL1; cullin 1
K03868 RBX1; RING-box protein 1 [EC:2.3.2.32]
K03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K06618 RB1; retinoblastoma-associated protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]
K09455 MITF; microphthalmia-associated transcription factor
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04462 MECOM; [histone H3]-lysine9 N-methyltransferase (ecotropic virus integration site 1 protein) [EC:2.1.1.367]
K04496 CTBP; C-terminal binding protein
K04496 CTBP; C-terminal binding protein
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K08734 MLH1; DNA mismatch repair protein MLH1
K08735 MSH2; DNA mismatch repair protein MSH2
K08736 MSH3; DNA mismatch repair protein MSH3
K08737 MSH6; DNA mismatch repair protein MSH6
K08775 BRCA2; breast cancer 2 susceptibility protein
K04482 RAD51; DNA repair protein RAD51
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K10131 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
K10132 BBC3; Bcl-2-binding component 3
K16341 BCL2L11; Bcl-2-like protein 11
K08738 CYC; cytochrome c
K08738 CYC; cytochrome c
K08738 CYC; cytochrome c
K08738 CYC; cytochrome c
K08738 CYC; cytochrome c
K08738 CYC; cytochrome c
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K10456 KLHL19; kelch-like protein 19
K05638 NFE2L2; nuclear factor erythroid 2-related factor 2
K00510 HMOX1; heme oxygenase 1 [EC:1.14.14.18]
K00355 NQO1; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K23790 GSTP; glutathione S-transferase P [EC:2.5.1.18]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K03871 VHL; von Hippel-Lindau disease tumor supressor
K03872 ELOC; elongin-C
K03872 ELOC; elongin-C
K03873 ELOB; elongin-B
K03873 ELOB; elongin-B
K03870 CUL2; cullin 2
K09592 EGLN; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K09592 EGLN; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K09592 EGLN; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K09095 HIF2A; hypoxia-inducible factor 2 alpha
K09097 ARNT; aryl hydrocarbon receptor nuclear translocator
K15589 ARNT2; aryl hydrocarbon receptor nuclear translocator 2
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K07299 SLC2A1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
K06052 JAG1; jagged-1
K21635 JAG2; jagged-2
K06051 DLL; delta
K06051 DLL; delta
K06051 DLL; delta
K02599 NOTCH1; Notch 1
K20994 NOTCH2; Notch 2
K20995 NOTCH3; Notch 3
K20996 NOTCH4; Notch 4
K06054 HES1; hairy and enhancer of split 1
K06055 HES5; hairy and enhancer of split 5
K09091 HEY; hairy and enhancer of split related with YRPW motif
K09091 HEY; hairy and enhancer of split related with YRPW motif
K09091 HEY; hairy and enhancer of split related with YRPW motif
K05097 FLT4; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K11988 SHH; sonic hedgehog
K06225 PTCH1; patched 1
K06226 SMO; smoothened
K18806 KIF7; kinesin family member 7
K06229 SUFU; suppressor of fused
K16797 GLI1; zinc finger protein GLI1
K16798 GLI2; zinc finger protein GLI2
K06230 GLI3; zinc finger protein GLI3
K21283 BMP2; bone morphogenetic protein 2
K04662 BMP4; bone morphogenetic protein 4
K06231 HHIP; hedgehog interacting protein
K11101 PTCH2; patched 2
K08557 AR; androgen receptor
K04079 HSP90A; molecular chaperone HtpG
K04079 HSP90A; molecular chaperone HtpG
K09487 HSP90B; heat shock protein 90kDa beta
K09487 HSP90B; heat shock protein 90kDa beta
K01351 KLK3; semenogelase [EC:3.4.21.77]
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05202 Transcriptional misregulation in cancer [PATH:nle05202]
|
05206 MicroRNAs in cancer [PATH:nle05206]
|
100605147 PTEN; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
100589956 CDKN1B; cyclin-dependent kinase inhibitor 1B
100594545 TIMP3; metalloproteinase inhibitor 3
100593773 KRAS; GTPase KRas isoform X1
100602542 CDK6; cyclin-dependent kinase 6
100588003 CDC25A; M-phase inducer phosphatase 1 isoform X1
100596941 CDC25B; M-phase inducer phosphatase 2 isoform X1
100588617 CDC25C; M-phase inducer phosphatase 3
115836938 HMGA2; high mobility group protein HMGI-C isoform X1
100605736 CCND1; G1/S-specific cyclin-D1
100585770 CCND2; G1/S-specific cyclin-D2
100607751 CCNE1; G1/S-specific cyclin-E1
100602200 CCNE2; G1/S-specific cyclin-E2
100595820 CRKL; crk-like protein
100601245 CRK; adapter molecule crk isoform X1
100581124 HDAC4; histone deacetylase 4 isoform X1
100585277 HDAC5; histone deacetylase 5 isoform X1
100602522 FOXP1; forkhead box protein P1 isoform X1
100580787 PIM1; serine/threonine-protein kinase pim-1
100597172 MET; hepatocyte growth factor receptor isoform X3
100594618 DNMT3A; DNA (cytosine-5)-methyltransferase 3A isoform X1
100598378 DNMT3B; DNA (cytosine-5)-methyltransferase 3B
100604947 MCL1; induced myeloid leukemia cell differentiation protein Mcl-1 isoform X1
100598768 bcl-2-like protein 2 isoform X2
100597255 EGFR; epidermal growth factor receptor isoform X1
100601396 VEGFA; vascular endothelial growth factor A isoform X1
100597823 ZEB1; zinc finger E-box-binding homeobox 1 isoform X7
100596183 TGFB2; transforming growth factor beta-2 proprotein isoform X1
100581958 EZR; ezrin isoform X1
100584426 PDCD4; programmed cell death protein 4
100589381 EP300; histone acetyltransferase p300
100596998 CREBBP; CREB-binding protein isoform X1
100591881 TPM1; tropomyosin alpha-1 chain isoform X18
100587795 SPRY2; protein sprouty homolog 2
100599011 BCL2; apoptosis regulator Bcl-2
100600262 SERPINB5; serpin B5 isoform X1
100583520 ST14; suppressor of tumorigenicity 14 protein
100583040 cytochrome P450 1B1
100594291 MTOR; serine/threonine-protein kinase mTOR isoform X1
100587259 RPTOR; regulatory-associated protein of mTOR
100603459 1
100601700 ERBB2; receptor tyrosine-protein kinase erbB-2 isoform X1
100590102 ERBB3; receptor tyrosine-protein kinase erbB-3
100601002 ABL1; tyrosine-protein kinase ABL1 isoform X1
100606847 TP63; tumor protein 63 isoform X3
100579944 ZEB2; zinc finger E-box-binding homeobox 2 isoform X1
100595362 FSCN1; fascin
100592827 RASSF1; ras association domain-containing protein 1 isoform X1
100586307 HOXD10; homeobox protein Hox-D10
100598015 DDIT4; DNA damage-inducible transcript 4 protein
100606908 BMF; bcl-2-modifying factor
100597455 PAK4; serine/threonine-protein kinase PAK 4 isoform X1
100587873 MMP9; matrix metalloproteinase-9
100593925 SLC7A1; high affinity cationic amino acid transporter 1
100588852 CCNG1; cyclin-G1
100587046 HMOX1; heme oxygenase 1
100596339 STMN1; stathmin
100598877 STAT3; signal transducer and activator of transcription 3 isoform X1
100589322 MYC; myc proto-oncogene protein
100585064 CASP3; caspase-3 isoform X3
100595274 HRAS; GTPase HRas isoform X1
100592103 NRAS; GTPase NRas
100592708 DNMT1; DNA (cytosine-5)-methyltransferase 1 isoform X1
100602025 APC2; adenomatous polyposis coli protein 2 isoform X1
100585467 APC; adenomatous polyposis coli protein isoform X3
100607873 IRS1; insulin receptor substrate 1
100605788 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1
100591270 PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1
100599301 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
100598787 MAPK7; mitogen-activated protein kinase 7 isoform X2
100588218 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
100580872 PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1
100584384 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1
100601168 HNRNPK; heterogeneous nuclear ribonucleoprotein K isoform X1
100592424 RECK; reversion-inducing cysteine-rich protein with Kazal motifs isoform X2
100594018 E2F3; transcription factor E2F3 isoform X1
100583956 IRS2; insulin receptor substrate 2
100602494 NOTCH1; neurogenic locus notch homolog protein 1 isoform X1
100584613 NOTCH2; neurogenic locus notch homolog protein 2 isoform X1
100590691 NOTCH3; neurogenic locus notch homolog protein 3
100600732 NOTCH4; neurogenic locus notch homolog protein 4
100584115 BMI1; polycomb complex protein BMI-1
100583949 MMP16; matrix metalloproteinase-16
100589181 SOCS1; suppressor of cytokine signaling 1
100587652 CD44; CD44 antigen isoform X3
100589247 DICER1; endoribonuclease Dicer isoform X1
100589994 FZD3; frizzled-3
100606925 ITGA5; integrin alpha-5
100601297 RDX; radixin isoform X2
100607291 RHOA; transforming protein RhoA
100581844 PLAU; urokinase-type plasminogen activator
100588483 BAK1; bcl-2 homologous antagonist/killer isoform X1
100607876 ZFPM2; zinc finger protein ZFPM2 isoform X1
100593791 ITGB3; integrin beta-3
100583288 UBE2I; SUMO-conjugating enzyme UBC9 isoform X1
100595042 SOX4; transcription factor SOX-4
100580126 TNN; tenascin-N isoform X1
100581667 TNR; tenascin-R isoform X1
100598677 TNC; tenascin
100597679 TNXB; tenascin-X isoform X1
100605124 ABCB1; ATP-dependent translocase ABCB1 isoform X1
100602390 ABCC1; multidrug resistance-associated protein 1
100580360 BRCA1; breast cancer type 1 susceptibility protein
100599083 CDKN1A; cyclin-dependent kinase inhibitor 1
100606614 EFNA5; ephrin-A5 isoform X1
100584794 EFNA1; ephrin-A1
100583129 EFNA3; ephrin-A3 isoform X1
100582330 EFNA4; ephrin-A4 isoform X3
100600655 EFNA2; ephrin-A2
100603886 THBS1; thrombospondin-1
100583575 IGF2BP1; insulin-like growth factor 2 mRNA-binding protein 1 isoform X1
100585311 TRIM71; E3 ubiquitin-protein ligase TRIM71
100581655 NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1
100588081 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1
100591090 PTGS2; prostaglandin G/H synthase 2
100600574 MAPK1; mitogen-activated protein kinase 1
100584480 MAPK3; mitogen-activated protein kinase 3
100591651 PRKCA; protein kinase C alpha type isoform X1
100590939 PRKCB; protein kinase C beta type isoform X2
100601464 PRKCG; protein kinase C gamma type
100588468 GRB2; growth factor receptor-bound protein 2
100591839 FGFR3; fibroblast growth factor receptor 3 isoform X1
100597734 RPS6KA5; ribosomal protein S6 kinase alpha-5 isoform X1
100583326 TP53; cellular tumor antigen p53
100601465 MDM2; E3 ubiquitin-protein ligase Mdm2 isoform X2
100594153 MDM4; protein Mdm4 isoform X1
100603207 PDGFRA; platelet-derived growth factor receptor alpha
100591458 PLCG1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1
100604145 PLCG2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
100582599 RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X1
100579506 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1
100591827 MAP2K2; dual specificity mitogen-activated protein kinase kinase 2
100590165 SOS1; son of sevenless homolog 1 isoform X1
100600495 SOS2; LOW QUALITY PROTEIN: son of sevenless homolog 2
100606068 SHC1; SHC-transforming protein 1 isoform X1
100583683 PDGFA; platelet-derived growth factor subunit A isoform X6
100591644 SHC4; SHC-transforming protein 4
100586714 PDGFB; platelet-derived growth factor subunit B
100597894 PDGFRB; platelet-derived growth factor receptor beta
100586796 CDKN2A; cyclin-dependent kinase inhibitor 2A isoform X1
100601097 E2F1; transcription factor E2F1
100583853 E2F2; transcription factor E2F2
100594069 BCL2L11; bcl-2-like protein 11 isoform X1
100591147 MARCKS; myristoylated alanine-rich C-kinase substrate
100599616 BMPR2; bone morphogenetic protein receptor type-2
100591684 HDAC2; histone deacetylase 2 isoform X1
100591033 HDAC1; histone deacetylase 1 isoform X3
100580962 EZH2; histone-lysine N-methyltransferase EZH2
100606824 GLS; glutaminase kidney isoform, mitochondrial isoform X1
100583191 GLS2; glutaminase liver isoform, mitochondrial isoform X2
100605499 SIRT1; NAD-dependent protein deacetylase sirtuin-1 isoform X1
100606846 WNT3A; protein Wnt-3a isoform X2
100599381 WNT3; proto-oncogene Wnt-3
100580441 CDCA5; sororin
100593002 KIF23; kinesin-like protein KIF23 isoform X2
100586590 ROCK1; rho-associated protein kinase 1
100606298 PRKCE; protein kinase C epsilon type isoform X1
100600742 SLC45A3; solute carrier family 45 member 3
100581876 VIM; vimentin
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K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K16866 TIMP3; metalloproteinase inhibitor 3
K07827 KRAS; GTPase KRas
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06645 CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48]
K05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
K05867 CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48]
K09283 HMGA2; high mobility group AT-hook protein 2
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K04438 CRK; C-crk adapter molecule crk
K04438 CRK; C-crk adapter molecule crk
K11406 HDAC4_5; histone deacetylase 4/5 [EC:3.5.1.98]
K11406 HDAC4_5; histone deacetylase 4/5 [EC:3.5.1.98]
K23582 FOXP1; forkhead box protein P1
K04702 PIM1; proto-oncogene serine/threonine-protein kinase Pim-1 [EC:2.7.11.1]
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K17398 DNMT3A; DNA (cytosine-5)-methyltransferase 3A [EC:2.1.1.37]
K17399 DNMT3B; DNA (cytosine-5)-methyltransferase 3B [EC:2.1.1.37]
K02539 MCL1; myeloid leukemia cell differntiation protein MCL-1
K02163 BCLW; apoptosis regulator BCL-W
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05448 VEGFA; vascular endothelial growth factor A
K09299 ZEB1; zinc finger homeobox protein 1
K13376 TGFB2; transforming growth factor beta-2
K08007 VIL2; villin 2 (ezrin)
K16865 PDCD4; programmed cell death protein 4
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K10373 TPM1; tropomyosin 1
K17383 SPRY2; protein sprouty homolog 2
K02161 BCL2; apoptosis regulator Bcl-2
K10139 SERPINB5; serpin B5
K08670 ST14; suppressor of tumorigenicity protein 14 [EC:3.4.21.109]
K07410 CYP1B1; cytochrome P450 family 1 subfamily B1 [EC:1.14.14.1]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K07204 RAPTOR; regulatory associated protein of mTOR
K07436 CYP24A1; vitamin D3 24-hydroxylase [EC:1.14.15.16]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K05084 ERBB3; receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1]
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K10149 TP63; tumor protein p63
K23560 ZEB2; zinc finger homeobox protein 2
K23551 FSCN1; fascin 1
K09850 RASSF1; Ras association domain-containing protein 1
K09295 HOXD10; homrobox protein Hox-D10
K08270 DDIT4; DNA-damage-inducible transcript 4
K17460 BMF; Bcl-2-modifying factor
K05734 PAK4; p21-activated kinase 4 [EC:2.7.11.1]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K13863 SLC7A1; solute carrier family 7 (cationic amino acid transporter), member 1
K10145 CCNG1; cyclin G1
K00510 HMOX1; heme oxygenase 1 [EC:1.14.14.18]
K04381 STMN1; stathmin
K04692 STAT3; signal transducer and activator of transcription 3
K04377 MYC; Myc proto-oncogene protein
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K02833 HRAS; GTPase HRas
K07828 NRAS; GTPase NRas
K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
K02085 APC; adenomatosis polyposis coli protein
K02085 APC; adenomatosis polyposis coli protein
K16172 IRS1; insulin receptor substrate 1
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04464 MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K12886 HNRNPK; heterogeneous nuclear ribonucleoprotein K
K17461 RECK; reversion-inducing-cysteine-rich protein with kazal motifs
K06620 E2F3; transcription factor E2F3
K07187 IRS2; insulin receptor substrate 2
K02599 NOTCH1; Notch 1
K20994 NOTCH2; Notch 2
K20995 NOTCH3; Notch 3
K20996 NOTCH4; Notch 4
K11459 PCGF4; polycomb group RING finger protein 4
K07996 MMP16; matrix metalloproteinase-16 (membrane-inserted) [EC:3.4.24.-]
K04694 SOCS1; suppressor of cytokine signaling 1
K06256 CD44; CD44 antigen
K11592 DICER1; endoribonuclease Dicer [EC:3.1.26.-]
K02329 FZD3; frizzled 3
K06484 ITGA5; integrin alpha 5
K05762 RDX; radixin
K04513 RHOA; Ras homolog gene family, member A
K01348 PLAU; urokinase plasminogen activator [EC:3.4.21.73]
K14021 BAK; Bcl-2 homologous antagonist/killer
K17442 ZFPM2; zinc finger protein ZFPM2
K06493 ITGB3; integrin beta 3
K10577 UBE2I; ubiquitin-conjugating enzyme E2 I
K23581 SOX4; transcription factor SOX4 (SOX group C)
K06252 TN; tenascin
K06252 TN; tenascin
K06252 TN; tenascin
K06252 TN; tenascin
K05658 ABCB1; ATP-binding cassette, subfamily B (MDR/TAP), member 1 [EC:7.6.2.2]
K05665 ABCC1; ATP-binding cassette, subfamily C (CFTR/MRP), member 1 [EC:7.6.2.3]
K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K16857 THBS1; thrombospondin 1
K17391 IGF2BP1; insulin-like growth factor 2 mRNA-binding protein 1
K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K11987 PTGS2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04364 GRB2; growth factor receptor-bound protein 2
K05094 FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K04445 RPS6KA5; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
K04451 TP53; tumor protein p53
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K10127 MDM4; protein Mdm4
K04363 PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K06279 SHC1; SHC-transforming protein 1
K04359 PDGFA; platelet-derived growth factor subunit A
K17449 SHC4; SHC-transforming protein 4
K17386 PDGFB; platelet-derived growth factor subunit B
K05089 PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K16341 BCL2L11; Bcl-2-like protein 11
K12561 MARCKS; myristoylated alanine-rich C-kinase substrate
K04671 BMPR2; bone morphogenetic protein receptor type-2 [EC:2.7.11.30]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K11430 EZH2; [histone H3]-lysine27 N-trimethyltransferase EZH2 [EC:2.1.1.356]
K01425 glsA; glutaminase [EC:3.5.1.2]
K01425 glsA; glutaminase [EC:3.5.1.2]
K11411 SIRT1; NAD+-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00312 WNT3; wingless-type MMTV integration site family, member 3
K17390 CDCA5; sororin
K17387 KIF23; kinesin family member 23
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K18050 PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
K15379 SLC45A3; solute carrier family 45, member 3
K07606 VIM; vimentin
|
05205 Proteoglycans in cancer [PATH:nle05205]
|
05204 Chemical carcinogenesis [PATH:nle05204]
|
05203 Viral carcinogenesis [PATH:nle05203]
|
05230 Central carbon metabolism in cancer [PATH:nle05230]
|
05231 Choline metabolism in cancer [PATH:nle05231]
|
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer [PATH:nle05235]
|
|
|
09162 Cancer: specific types
|
05210 Colorectal cancer [PATH:nle05210]
|
05212 Pancreatic cancer [PATH:nle05212]
|
05225 Hepatocellular carcinoma [PATH:nle05225]
|
05226 Gastric cancer [PATH:nle05226]
|
05214 Glioma [PATH:nle05214]
|
05216 Thyroid cancer [PATH:nle05216]
|
05221 Acute myeloid leukemia [PATH:nle05221]
|
05220 Chronic myeloid leukemia [PATH:nle05220]
|
05217 Basal cell carcinoma [PATH:nle05217]
|
05218 Melanoma [PATH:nle05218]
|
05211 Renal cell carcinoma [PATH:nle05211]
|
05219 Bladder cancer [PATH:nle05219]
|
100591839 FGFR3; fibroblast growth factor receptor 3 isoform X1
100595274 HRAS; GTPase HRas isoform X1
100593773 KRAS; GTPase KRas isoform X1
100592103 NRAS; GTPase NRas
100595311 ARAF; serine/threonine-protein kinase A-Raf
100582848 BRAF; serine/threonine-protein kinase B-raf isoform X2
100582599 RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X1
100579506 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1
100591827 MAP2K2; dual specificity mitogen-activated protein kinase kinase 2
100600574 MAPK1; mitogen-activated protein kinase 1
100584480 MAPK3; mitogen-activated protein kinase 3
100597734 RPS6KA5; ribosomal protein S6 kinase alpha-5 isoform X1
100589322 MYC; myc proto-oncogene protein
100592827 RASSF1; ras association domain-containing protein 1 isoform X1
100590142 DAPK3; death-associated protein kinase 3
100603623 DAPK1; death-associated protein kinase 1 isoform X1
100598470 DAPK2; death-associated protein kinase 2 isoform X2
100586796 CDKN2A; cyclin-dependent kinase inhibitor 2A isoform X1
100601465 MDM2; E3 ubiquitin-protein ligase Mdm2 isoform X2
100583326 TP53; cellular tumor antigen p53
100599083 CDKN1A; cyclin-dependent kinase inhibitor 1
100605736 CCND1; G1/S-specific cyclin-D1
100594967 CDK4; cyclin-dependent kinase 4
100588629 RB1; retinoblastoma-associated protein
100601097 E2F1; transcription factor E2F1
100583853 E2F2; transcription factor E2F2
100594018 E2F3; transcription factor E2F3 isoform X1
100603886 THBS1; thrombospondin-1
100600047 HBEGF; proheparin-binding EGF-like growth factor
100597186 MMP2; 72 kDa type IV collagenase isoform X1
100587873 MMP9; matrix metalloproteinase-9
105740017 UPK3A; uroplakin-3a isoform X1
100602214 SRC; proto-oncogene tyrosine-protein kinase Src isoform X1
100588963 EGF; pro-epidermal growth factor isoform X1
100601700 ERBB2; receptor tyrosine-protein kinase erbB-2 isoform X1
100597255 EGFR; epidermal growth factor receptor isoform X1
115835926 TYMP; thymidine phosphorylase
100601396 VEGFA; vascular endothelial growth factor A isoform X1
100582292 MMP1; interstitial collagenase isoform X1
100586157 CXCL8; interleukin-8
100596627 CDH1; cadherin-1 isoform X1
|
K05094 FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04445 RPS6KA5; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
K04377 MYC; Myc proto-oncogene protein
K09850 RASSF1; Ras association domain-containing protein 1
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53; tumor protein p53
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04503 CCND1; G1/S-specific cyclin-D1
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K16857 THBS1; thrombospondin 1
K08523 HBEGF; heparin-binding EGF-like growth factor
K01398 MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K19520 UPK3A; uroplakin-3a
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K04357 EGF; epidermal growth factor
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K00758 deoA; thymidine phosphorylase [EC:2.4.2.4]
K05448 VEGFA; vascular endothelial growth factor A
K01388 MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
K10030 IL8; interleukin 8
K05689 CDH1; cadherin 1, type 1, E-cadherin
|
05215 Prostate cancer [PATH:nle05215]
|
05213 Endometrial cancer [PATH:nle05213]
|
05224 Breast cancer [PATH:nle05224]
|
05222 Small cell lung cancer [PATH:nle05222]
|
05223 Non-small cell lung cancer [PATH:nle05223]
|
100587886 FHIT; bis(5'-adenosyl)-triphosphatase isoform X1
100596579 RARB; retinoic acid receptor beta isoform X2
100585339 RXRA; retinoic acid receptor RXR-alpha isoform X1
100580742 RXRB; retinoic acid receptor RXR-beta isoform X2
100592610 RXRG; retinoic acid receptor RXR-gamma
100586796 CDKN2A; cyclin-dependent kinase inhibitor 2A isoform X1
100594967 CDK4; cyclin-dependent kinase 4
100602542 CDK6; cyclin-dependent kinase 6
100605736 CCND1; G1/S-specific cyclin-D1
100588629 RB1; retinoblastoma-associated protein
100601097 E2F1; transcription factor E2F1
100583853 E2F2; transcription factor E2F2
100594018 E2F3; transcription factor E2F3 isoform X1
100593773 KRAS; GTPase KRas isoform X1
100592827 RASSF1; ras association domain-containing protein 1 isoform X1
100607511 RASSF5; ras association domain-containing protein 5 isoform X1
100599164 STK4; serine/threonine-protein kinase 4
100588218 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
100580872 PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1
100584384 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1
100605788 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1
100591270 PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1
100599301 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
100593010 3-phosphoinositide-dependent protein kinase 1 isoform X1
115831277 LOW QUALITY PROTEIN: putative 3-phosphoinositide-dependent protein kinase 2
100604331 AKT3; RAC-gamma serine/threonine-protein kinase isoform X1
100587864 AKT2; RAC-beta serine/threonine-protein kinase isoform X1
100587109 AKT1; RAC-alpha serine/threonine-protein kinase
101178725 BAD; bcl2-associated agonist of cell death
100597173 CASP9; caspase-9 isoform X1
100600519 FOXO3; forkhead box protein O3
100588963 EGF; pro-epidermal growth factor isoform X1
100607585 TGFA; protransforming growth factor alpha isoform X3
100597255 EGFR; epidermal growth factor receptor isoform X1
100601700 ERBB2; receptor tyrosine-protein kinase erbB-2 isoform X1
100586296 HGF; hepatocyte growth factor isoform X1
100597172 MET; hepatocyte growth factor receptor isoform X3
100588468 GRB2; growth factor receptor-bound protein 2
100590165 SOS1; son of sevenless homolog 1 isoform X1
100600495 SOS2; LOW QUALITY PROTEIN: son of sevenless homolog 2
100595274 HRAS; GTPase HRas isoform X1
100592103 NRAS; GTPase NRas
100595311 ARAF; serine/threonine-protein kinase A-Raf
100582848 BRAF; serine/threonine-protein kinase B-raf isoform X2
100582599 RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X1
100579506 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1
100591827 MAP2K2; dual specificity mitogen-activated protein kinase kinase 2
100600574 MAPK1; mitogen-activated protein kinase 1
100584480 MAPK3; mitogen-activated protein kinase 3
100591458 PLCG1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1
100604145 PLCG2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
100591651 PRKCA; protein kinase C alpha type isoform X1
100590939 PRKCB; protein kinase C beta type isoform X2
100601464 PRKCG; protein kinase C gamma type
100583326 TP53; cellular tumor antigen p53
100599083 CDKN1A; cyclin-dependent kinase inhibitor 1
100593432 GADD45G; growth arrest and DNA damage-inducible protein GADD45 gamma
100583800 GADD45A; growth arrest and DNA damage-inducible protein GADD45 alpha
115830865 GADD45B; growth arrest and DNA damage-inducible protein GADD45 beta
100593013 BAX; apoptosis regulator BAX isoform X1
100588483 BAK1; bcl-2 homologous antagonist/killer isoform X1
100605065 DDB2; DNA damage-binding protein 2 isoform X1
100598341 POLK; DNA polymerase kappa isoform X1
100589788 KIF5B; kinesin-1 heavy chain
100579859 KIF5A; kinesin heavy chain isoform X1
100591941 KIF5C; kinesin heavy chain
100602103 RET; proto-oncogene tyrosine-protein kinase receptor Ret isoform X1
100595819 EML4; echinoderm microtubule-associated protein-like 4 isoform X1
100593886 ALK; ALK tyrosine kinase receptor
100603367 tyrosine-protein kinase JAK3 isoform X1
100598877 STAT3; signal transducer and activator of transcription 3 isoform X1
100602815 signal transducer and activator of transcription 5A isoform X1
100602489 signal transducer and activator of transcription 5B isoform X1
|
K01522 FHIT; bis(5'-adenosyl)-triphosphatase [EC:3.6.1.29]
K08528 RARB; retinoic acid receptor beta
K08524 RXRA; retinoid X receptor alpha
K08525 RXRB; retinoid X receptor beta
K08526 RXRG; retinoid X receptor gamma
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K04503 CCND1; G1/S-specific cyclin-D1
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K07827 KRAS; GTPase KRas
K09850 RASSF1; Ras association domain-containing protein 1
K08015 RASSF5; Ras association domain-containing protein 5
K04411 STK4; serine/threonine kinase 4
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K09408 FOXO3; forkhead box protein O3
K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K05460 HGF; hepatocyte growth factor
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04451 TP53; tumor protein p53
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K10396 KIF5; kinesin family member 5
K10396 KIF5; kinesin family member 5
K10396 KIF5; kinesin family member 5
K05126 RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
K15420 EML4; echinoderm microtubule-associated protein-like 4
K05119 ALK; anaplastic lymphoma kinase [EC:2.7.10.1]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
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09163 Immune disease
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09164 Neurodegenerative disease
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09165 Substance dependence
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09166 Cardiovascular disease
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09167 Endocrine and metabolic disease
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09171 Infectious disease: bacterial
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09172 Infectious disease: viral
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09174 Infectious disease: parasitic
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09175 Drug resistance: antimicrobial
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09176 Drug resistance: antineoplastic
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09180 Brite Hierarchies
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09190 Not Included in Pathway or Brite
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KEGG Orthology (KO) - Nomascus leucogenys (northern white-cheeked gibbon)