| C00220 |
Methylene blue; Methylthioninium chloride |
(P) unclassified |
| C06174 |
Codeine; (5alpha,6alpha)-7,8-Didehydro-4,5-epoxy-3-methoxy-17-methylmorphinan-6-ol |
(P) unclassified |
| C06921 |
Clorazepate; Clorazepic acid |
(P) unclassified |
| C07051 |
Indinavir |
(P) unclassified |
| C07055 |
Isopropamide |
(P) unclassified |
| C07506 |
Propantheline |
(P) unclassified |
| C07811 |
Hexocyclium |
(P) unclassified |
| C07814 |
Homatropine |
(P) unclassified |
| C07818 |
Mepenzolate |
(P) unclassified |
| C07849 |
Methantheline |
(P) unclassified |
| C07861 |
Tridihexethyl |
(P) unclassified |
| C12768 |
Timepidium bromide; Timepidium bromide anhydrous |
(P) unclassified |
| D00059 |
Levodopa (JP18/USP/INN); Dopar (TN) |
(P) Target: DRD4 |
| D00076 |
Noradrenaline (JP18); Norepinephrine (INN) |
(CI) Target: ADRA2A ADRA2B ADRA2C |
| D00095 |
Epinephrine (USP/INN); Adrenaline (JP18); Auvi-q (TN); Epipen (TN) |
(CI,P) Target: ADRA2A ADRA2B ADRA2C |
| D00113 |
Atropine (USP); Atropen (TN) |
(P) unclassified |
| D00124 |
Ephedrine (USP) |
(CI) Target: ADRA2A ADRA2B ADRA2C |
| D00131 |
Disulfiram (JP18/USP/INN); Antabuse (TN) |
(P) CYP inhibition: CYP1A2 |
| D00136 |
Haloperidol (JP18/USP/INN); Haldol (TN) |
(P) Enzyme: CYP3A4 |
| D00138 |
Scopolamine (INN); Transderm scop (TN) |
(P) unclassified |
| D00140 |
Erythromycin (JP18/USP/INN); Akne-mycin (TN); Eryc (TN); Erygel (TN); Pce (TN); Staticin (TN); T-stat (TN) |
(P) unclassified |
| D00147 |
Hyoscyamine (USP) |
(P) unclassified |
| D00184 |
Cyclosporine (USP); Ciclosporin (JP18); Gengraf (TN); Neoral (TN); Restasis (TN); Sandimmune (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D00186 |
Ciprofloxacin (JP18/USP/INN); Cipro (TN); Otiprio (TN) |
(P) CYP inhibition: CYP1A2 |
| D00195 |
Codeine (USP); Codeine hydrate |
(P) unclassified |
| D00197 |
Reserpine (JP18/USP/INN); Apoplon (TN); Serpalan (TN) |
(P) unclassified |
| D00198 |
Rescinnamine (JAN/INN); Tsuruselpi S (TN) |
(P) unclassified |
| D00210 |
Norfloxacin (JP18/USP/INN); Noroxin (TN) |
(P) Enzyme: CYP1A2 / CYP inhibition: CYP1A2 |
| D00211 |
Rifampin (USP); Rifampicin (JP18/INN); Rifadin (TN); Rimactane (TN) |
(P) CYP induction: CYP3A4 |
| D00224 |
Allopurinol (JP18/USP/INN); Zyloprim (TN) |
(P) CYP inhibition: CYP1A2 |
| D00225 |
Alprazolam (JP18/USP/INN); Xanax (TN) |
(P) unclassified |
| D00232 |
Anisotropine methylbromide (USAN); Octatropine methylbromide (INN); Methyloctatropine bromide (JAN); Valpin (TN); Valpin 50 (TN) |
(P) unclassified |
| D00234 |
Astemizole (JAN/USP/INN); Hismanal (TN) |
(P) unclassified |
| D00252 |
Carbamazepine (JP18/USP/INN); Equetro (TN); Tegretol (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D00253 |
Carbidopa hydrate and levodopa; Parcopa (TN); Sinemet (TN) |
(P) unclassified |
| D00267 |
Chlordiazepoxide (JP18/USP/INN); Libritabs (TN) |
(P) unclassified |
| D00270 |
Chlorpromazine (USP/INN); Thorazine (TN) |
(P) Target: ADRA2A ADRA2B ADRA2C HTR2A HTR2C |
| D00276 |
Clarithromycin (JP18/USP/INN); Biaxin (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D00280 |
Clonazepam (JP18/USP/INN); Klonopin (TN) |
(P) unclassified |
| D00281 |
Clonidine (JAN/USP/INN); Catarpres-TTS (TN) |
(CI,P) Target: ADRA2A ADRA2B ADRA2C |
| D00282 |
Clotrimazole (JP18/USP/INN); Lotrimin (TN); Mycelex (TN) |
(P) CYP inhibition: CYP3A4 |
| D00292 |
Dexamethasone (JP18/USP/INN); Decadron (TN); Maxidex (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D00293 |
Diazepam (JP18/USP/INN); Diastat (TN); Valium (TN) |
(P) Enzyme: CYP3A4 |
| D00294 |
Diazoxide (JAN/USP/INN); Hyperstat (TN); Proglycem (TN) |
(P) Enzyme: CYP1A2 |
| D00295 |
Cimetidine (JP18/USP/INN); Tagamet (TN) |
(P) CYP inhibition: CYP3A4 |
| D00300 |
Diphenhydramine (JP18/INN); Restamin (TN) |
(P) unclassified |
| D00304 |
Divalproex sodium (USP); Valproate semisodium (INN); Depakote (TN) |
(P) unclassified |
| D00310 |
Enoxacin (USAN/INN); Penetrex (TN) |
(P) CYP inhibition: CYP1A2 |
| D00311 |
Estazolam (JP18/USP/INN); ProSom (TN) |
(P) unclassified |
| D00318 |
Famotidine (JP18/USP/INN); Fluxid (TN); Pepcid (TN) |
(P) CYP inhibition: CYP1A2 |
| D00320 |
Fentanyl (JAN/USP/INN); Duragesic (TN); Subsys (TN) |
(P) Enzyme: CYP3A4 |
| D00322 |
Fluconazole (JP18/USP/INN); Diflucan (TN) |
(P) CYP inhibition: CYP3A4 |
| D00329 |
Flurazepam (JAN/INN); Insumin (TN) |
(P) unclassified |
| D00338 |
Halazepam (USAN/INN); Paxipam (TN) |
(P) unclassified |
| D00346 |
Isoniazid (JP18/USP/INN); Laniazid (TN) |
(P) unclassified |
| D00350 |
Itraconazole (JP18/USP); Itrizole (TN); Sporanox (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D00351 |
Ketoconazole (JP18/USP); Nizoral (TN); Xolegel (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D00364 |
Loratadine (JAN/USP/INN); Claritin (TN) |
(P) Enzyme: CYP3A4 |
| D00365 |
Lorazepam (JP18/USP/INN); Ativan (TN) |
(P) unclassified |
| D00370 |
Temazepam (USP/INN); Restoril (TN) |
(P) unclassified |
| D00387 |
Triazolam (JP18/USP/INN); Halcion (TN) |
(P) Enzyme: CYP3A4 |
| D00397 |
Tropicamide (JP18/USP/INN); Mydriacyl (TN) |
(P) unclassified |
| D00399 |
Valproic acid (USP); Depakene (TN) |
(P) unclassified |
| D00405 |
Methyldopa (USP); Methyldopa hydrate (JP18); Aldomet (TN) |
(CI,P) Target: ADRA2A ADRA2B ADRA2C |
| D00418 |
Minoxidil (JAN/USP/INN); Loniten (TN); Riup (TN); Rogaine (TN) |
(P) unclassified |
| D00420 |
Mitotane (JAN/USP/INN); Lysodren (TN) |
(P) unclassified |
| D00426 |
Risperidone (JP18/USP/INN); Risperdal (TN) |
(CI) Enzyme: CYP3A4 / Target: HTR2A |
| D00427 |
Ritonavir (JAN/USP/INN); Norvir (TN) |
(P) CYP induction: CYP1A2 |
| D00435 |
Nevirapine (JAN/USP/INN); Viramune (TN) |
(P) Enzyme: CYP3A4 |
| D00454 |
Olanzapine (JAN/USP/INN); Zyprexa (TN) |
(P) Enzyme: CYP1A2 / Target: DRD4 HTR2A HTR2C |
| D00455 |
Omeprazole (JP18/USP/INN); Prilosec (TN) |
(P) unclassified |
| D00457 |
Quazepam (JAN/USP/INN); Doral (TN) |
(P) Enzyme: CYP3A4 |
| D00458 |
Quetiapine fumarate (JP18/USP); Seroquel (TN) |
(P) Enzyme: CYP3A4 / Target: HTR2A |
| D00464 |
Oxazepam (JAN/USP/INN); Serax (TN) |
(P) unclassified |
| D00465 |
Oxybutynin (USAN/INN); Anturol (TN); Oxytrol (TN) |
(P) Enzyme: CYP3A4 |
| D00470 |
Prazepam (JP18/USAN/INN); Centrax (TN) |
(P) unclassified |
| D00480 |
Promethazine hydrochloride (JP18/USP); Phenergan (TN); Promethegan (TN) |
(P) unclassified |
| D00481 |
Propantheline bromide (JP18/USP/INN); Pro-banthine (TN) |
(P) unclassified |
| D00482 |
Propoxyphene hydrochloride (USAN); Dextropropoxyphene hydrochloride; Darvon (TN) |
(P) unclassified |
| D00485 |
Pseudoephedrine hydrochloride (USP); Sudafed (TN) |
(CI) Target: ADRA2A ADRA2B ADRA2C |
| D00494 |
Promethazine (JAN/INN) |
(P) unclassified |
| D00498 |
Pentazocine (JP18/USP/INN); Fortral (TN) |
(P) unclassified |
| D00502 |
Pergolide mesylate (USP); Pergolide mesilate (JAN); Permax (TN) |
(P) unclassified |
| D00505 |
Phenelzine sulfate (USP); Nardil (TN) |
(P) unclassified |
| D00506 |
Phenobarbital (JP18/USP/INN); Luminal (TN) |
(P) unclassified |
| D00511 |
Phenylephrine hydrochloride (JP18/USP); Neo-synephrine (TN) |
(CI) unclassified |
| D00512 |
Phenytoin (JP18/USP/INN); Dilantin (TN) |
(P) unclassified |
| D00514 |
Dexmedetomidine (USAN/INN); Dexdor (TN); Precedex (TN) |
(CI) Target: ADRA2A ADRA2B ADRA2C |
| D00520 |
Dimenhydrinate (JP18/USP/INN); Dramamine (TN) |
(P) unclassified |
| D00521 |
Terfenadine (JAN/USAN/INN); Seldane (TN) |
(P) unclassified |
| D00528 |
Caffeine (USP); Anhydrous caffeine (JP18); Anhydrous caffeine (TN); Respia (TN) |
(P) Enzyme: CYP1A2 |
| D00531 |
Nitrazepam (JP18/USAN/INN); Benzalin (TN); Nitrazepam (TN) |
(P) unclassified |
| D00540 |
Glycopyrrolate (USP); Glycopyrronium bromide (JAN/INN); Cuvposa (TN); Robinul (TN); Seebri breezhaler (TN) |
(P) unclassified |
| D00550 |
Midazolam (JAN/USP/INN); Dormicum (TN); Buccolam (TN); Nayzilam (TN) |
(P) Enzyme: CYP3A4 |
| D00554 |
Ethinyl estradiol (USP); Ethinylestradiol (JP18/INN); Estinyl (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D00559 |
Pramipexole dihydrochloride (USP); Pramipexole hydrochloride hydrate (JAN); Pramipexole dihydrochloride monohydrate; Mirapex (TN) |
(P) Target: DRD4 |
| D00578 |
Voriconazole (JP18/USP/INN); Vfend (TN) |
(P) unclassified |
| D00604 |
Clonidine hydrochloride (JP18/USP); Nexiclon (TN); Kapvay (TN); Duraclon (TN); Catapres (TN) |
(CI,P) Target: ADRA2A ADRA2B ADRA2C |
| D00606 |
Guanfacine hydrochloride (JAN/USP); Intuniv (TN); Tenex (TN) |
(CI,P) Enzyme: CYP3A4 / Target: ADRA2A |
| D00607 |
Guanadrel sulfate (USAN); Hylorel (TN) |
(CI) Target: ADRA2A ADRA2B ADRA2C |
| D00608 |
Doxazosin mesylate (USP); Doxazosin mesilate (JP18); Cardura (TN) |
(P) unclassified |
| D00609 |
Prazosin hydrochloride (JP18/USP); Minipress (TN) |
(P) unclassified |
| D00611 |
Mecamylamine hydrochloride (USP); Inversine (TN) |
(P) unclassified |
| D00612 |
Trimetaphan camsilate (JAN/INN); Trimetaphan camsylate; Arfonad (TN) |
(P) unclassified |
| D00614 |
Sodium nitroprusside (USP); Sodium nitroprusside hydrate (JAN); Nitropress (TN) |
(P) unclassified |
| D00619 |
Verapamil hydrochloride (JP18/USP); Calan (TN); Covera-hs (TN); Vasolan (TN); Verelan (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D00632 |
Dobutamine hydrochloride (JP18/USP); Dobutrex (TN) |
(CI) unclassified |
| D00636 |
Amiodarone hydrochloride (JP18/USP); Ancaron (TN); Cordarone (TN); Nexterone (TN) |
(CI,P) Enzyme: CYP3A4 |
| D00646 |
Tolterodine (USAN/INN) |
(P) Enzyme: CYP3A4 |
| D00659 |
Azelastine hydrochloride (JP18/USP); Astelin (TN) |
(P) unclassified |
| D00662 |
Azatadine maleate (USP); Optimine (TN) |
(P) unclassified |
| D00663 |
Brompheniramine maleate (USP); Dimetane (TN) |
(P) unclassified |
| D00664 |
Cetirizine hydrochloride (JP18/USP); Zyrtec (TN) |
(P) unclassified |
| D00665 |
Chlorpheniramine maleate (JP18/USP); Chlor-trimeton (TN); Teldrin (TN) |
(P) unclassified |
| D00666 |
Clemastine fumarate (JP18/USP); Tavist (TN) |
(P) unclassified |
| D00668 |
Dexchlorpheniramine maleate (USP); d-Chlorpheniramine maleate (JP18); Mylaramine (TN); Polaramine (TN) |
(P) unclassified |
| D00669 |
Diphenhydramine hydrochloride (JP18/USP); Benadryl (TN) |
(P) unclassified |
| D00671 |
Fexofenadine hydrochloride (JP18/USP); Allegra (TN) |
(P) unclassified |
| D00672 |
Hydroxyzine hydrochloride (JP18/USP); Hydroxyzine dihydrochloride; Atarax (TN); Vistaril (TN) |
(P) unclassified |
| D00683 |
Albuterol sulfate (USP); Salbutamol sulfate (JP18); Accuneb (TN); Proventil (TN); Ventolin (TN) |
(CI) unclassified |
| D00684 |
Bitolterol mesylate (USAN); Bitolterol mesilate (JAN); Tornalate (TN) |
(CI) unclassified |
| D00685 |
Metaproterenol sulfate (USP); Orciprenaline sulfate (JP18); Alupent (TN) |
(CI) unclassified |
| D00686 |
Pirbuterol acetate (USAN); Maxair (TN) |
(CI) unclassified |
| D00687 |
Salmeterol xinafoate (JAN/USP); Serevent (TN) |
(CI) Enzyme: CYP3A4 |
| D00688 |
Terbutaline sulfate (JP18/USP); Brethine (TN) |
(CI) unclassified |
| D00693 |
Chlordiazepoxide hydrochloride (JAN/USP); Librium (TN) |
(P) unclassified |
| D00694 |
Clorazepate dipotassium (JP18/USP); Tranxene (TN) |
(P) unclassified |
| D00695 |
Flurazepam hydrochloride (USP); Flurazepam dihydrochloride; Dalmane (TN) |
(P) unclassified |
| D00696 |
Midazolam hydrochloride (USAN); Versed (TN) |
(P) Enzyme: CYP3A4 |
| D00701 |
Phenobarbital sodium (JAN/USP/INN); Luminal sodium (TN) |
(P) unclassified |
| D00707 |
Fomepizole (JAN/USAN/INN); Antizol (TN) |
(P) CYP inhibition: CYP1A2 CYP3A4 |
| D00710 |
Valproate sodium (USAN); Sodium valproate (JP18); Depakene (TN); Selenica (TN) |
(P) unclassified |
| D00715 |
Methscopolamine bromide (USP); Hyoscine methobromide (INN); Pamine (TN) |
(P) unclassified |
| D00716 |
Clidinium bromide (USP/INN); Quarzan (TN) |
(P) unclassified |
| D00717 |
Dicyclomine hydrochloride (JAN/USP); Dicycloverine hydrochloride; Bentyl (TN); Urispas (TN) |
(P) unclassified |
| D00719 |
Hyoscyamine sulfate (USP); Hyoscyamine sulfate dihydrate; Egacene (TN) |
(P) unclassified |
| D00720 |
Mepenzolate bromide (JP18/INN); Cantil (TN) |
(P) unclassified |
| D00721 |
Methanthelinium bromide (INN); Methantheline bromide; Banthine (TN) |
(P) unclassified |
| D00722 |
Oxybutynin chloride (USP); Oxybutynin hydrochloride (JP18); Ditropan (TN); Gelnique (TN) |
(P) Enzyme: CYP3A4 |
| D00723 |
Tridihexethyl chloride (BAN); Pathilon (TN) |
(P) unclassified |
| D00743 |
Naphazoline hydrochloride (JP18/USP); Albalon (TN); Vasocon (TN) |
(CI) unclassified |
| D00753 |
Sirolimus (JAN/USAN/INN); Rapamune (TN); Rapamycin (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D00756 |
Tetrahydrozoline nitrate (JAN); Narbel (TN) |
(CI) unclassified |
| D00762 |
Metyrosine (USP); Metirosine (JAN/INN); Demser (TN) |
(P) unclassified |
| D00774 |
Orphenadrine citrate (USP); Norflex (TN) |
(P) unclassified |
| D00776 |
Tizanidine hydrochloride (JP18/USP); Zanaflex (TN) |
(CI) Enzyme: CYP1A2 / Target: ADRA2A ADRA2B ADRA2C |
| D00778 |
Benztropine mesylate (USP); Benztropine mesilate (JAN); Cogentin (TN) |
(P) unclassified |
| D00779 |
Biperiden (JAN/USP/INN); Akineton (TN) |
(P) unclassified |
| D00780 |
Bromocriptine mesylate (USP); Bromocriptine mesilate (JP18); Parlodel (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D00782 |
Procyclidine hydrochloride (USP); Kemadrin (TN) |
(P) unclassified |
| D00784 |
Ropinirole hydrochloride (JAN/USP); Requip (TN) |
(P) Enzyme: CYP1A2 / Target: DRD4 |
| D00785 |
Selegiline hydrochloride (JAN/USP); Eldepryl (TN) |
(P) Enzyme: CYP3A4 |
| D00787 |
Trihexyphenidyl hydrochloride (JP18/USP); Artane (TN) |
(P) unclassified |
| D00789 |
Chlorpromazine hydrochloride (JP18/USP); Sonazine (TN) |
(P) Target: ADRA2A ADRA2B ADRA2C HTR2A HTR2C |
| D00793 |
Fluphenazine decanoate (JAN/USP); Prolixin decanoate (TN) |
(CI) unclassified |
| D00801 |
Lithium carbonate (JP18/USP); Eskalith (TN); Lithobid (TN) |
(P) unclassified |
| D00824 |
Fluvoxamine maleate (JP18/USP); Luvox (TN) |
(P) CYP inhibition: CYP1A2 CYP3A4 |
| D00825 |
Sertraline hydrochloride (JAN/USP); Zoloft (TN) |
(P) Enzyme: CYP3A4 |
| D00826 |
Tranylcypromine sulfate (USP); Parnate (TN) |
(P) unclassified |
| D00831 |
Mefloquine hydrochloride (JP18/USP); Lariam (TN) |
(P) unclassified |
| D00835 |
Alfentanil hydrochloride (USP); Alfenta (TN) |
(P) unclassified |
| D00836 |
Buprenorphine hydrochloride (JP18/USP); Buprenex (TN) |
(P) Enzyme: CYP3A4 |
| D00837 |
Butorphanol tartrate (JAN/USP); Stadol (TN) |
(P) unclassified |
| D00838 |
Dezocine (USAN); Dalgan (TN) |
(P) unclassified |
| D00839 |
Hydromorphone hydrochloride (JAN/USP); Dilaudid (TN); Exalgo (TN); Palladone (TN) |
(P) unclassified |
| D00840 |
Levomethadyl acetate hydrochloride (USAN); Orlaam (TN) |
(P) Enzyme: CYP3A4 |
| D00841 |
Levorphanol tartrate (USP); Levorphanol tartrate dihydrate; Levo-dromoran (TN) |
(P) unclassified |
| D00842 |
Morphine sulfate (USP); Morphine sulfate hydrate (JP18); Morphine sulfate pentahydrate; Astramor PH (TN); Avinza (TN); Depodur (TN); Kadian (TN); MS contin (TN) |
(P) unclassified |
| D00843 |
Nalbuphine hydrochloride (USAN); Nubain (TN) |
(P) unclassified |
| D00844 |
Oxymorphone hydrochloride (USP); Numorphan (TN); Opana (TN) |
(P) unclassified |
| D00845 |
Sufentanil citrate (USP); Dsuvia (TN); Sufenta (TN) |
(P) unclassified |
| D00847 |
Oxycodone hydrochloride (USP); Oxecta (TN); Oxycontin (TN); Roxicodone (TN) |
(P) Enzyme: CYP3A4 |
| D00851 |
Erythromycin estolate (USP); Erythromycin estorate (JAN); Ilosone (TN) |
(P) unclassified |
| D00854 |
Quinupristin and dalfopristin; Synercid (TN) |
(P) CYP inhibition: CYP3A4 |
| D00874 |
Moxifloxacin hydrochloride (JAN/USP); Avelox (TN); Vigamox (TN) |
(P) unclassified |
| D00879 |
Rifapentine (USAN/INN); Priftin (TN) |
(P) CYP induction: CYP3A4 |
| D00896 |
Efavirenz (JAN/USP/INN); Sustiva (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D00897 |
Indinavir sulfate (USP); Crixivan (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D00899 |
Nelfinavir mesylate (USAN/INN); Nelfinavir mesilate (JAN); Viracept (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D00960 |
Anastrozole (JP18/USP/INN); Arimidex (TN) |
(P) CYP inhibition: CYP1A2 CYP3A4 |
| D00961 |
Bicalutamide (JP18/USP/INN); Casodex (TN) |
(P) CYP inhibition: CYP3A4 |
| D00975 |
Dexamethasone sodium phosphate (JAN/USP); Dalalone (TN); Maxidex (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D00987 |
Cabergoline (JP18/USP/INN); Cabaser (TN); Dostinex (TN) |
(P) Enzyme: CYP3A4 |
| D00996 |
Epinephrine hydrochloride (JAN); Adrenalin chloride (TN) |
(CI) Target: ADRA2A ADRA2B ADRA2C |
| D01002 |
Cyclopentolate hydrochloride (JP18/USP); Cyclogyl (TN) |
(P) unclassified |
| D01003 |
Hexocyclium metilsulfate (INN); Hexocyclium methyl sulfate; Tral (TN) |
(P) unclassified |
| D01004 |
Homatropine hydrobromide (JP18/USP); Isopto homatropine (TN) |
(P) unclassified |
| D01005 |
Isopropamide iodide (JAN/USP/INN); Darbid (TN) |
(P) unclassified |
| D01006 |
Oxyphencyclimine hydrochloride (JAN); Daricon (TN) |
(P) unclassified |
| D01007 |
Propiverine hydrochloride (JP18); Bup-4 (TN); Mictonorm (TN) |
(P) Enzyme: CYP3A4 |
| D01008 |
Apraclonidine hydrochloride (JAN/USP); Iopidine (TN) |
(CI) Target: ADRA2A ADRA2B ADRA2C |
| D01017 |
Dipivefrin hydrochloride (USP); Dipivefrine hydrochloride (JAN); Propine (TN) |
(CI) Target: ADRA2A ADRA2B ADRA2C |
| D01019 |
Metaraminol bitartrate (JAN/USP); Aramine (TN) |
(CI) Target: ADRA2A ADRA2B ADRA2C |
| D01020 |
Methoxamine hydrochloride (JAN); Vasoxyl (TN) |
(CI) unclassified |
| D01021 |
Naphazoline nitrate (JP18); Privine (TN) |
(CI) unclassified |
| D01022 |
Oxymetazoline hydrochloride (JAN/USP); Ocuclear (TN); Rhfade (TN) |
(CI) unclassified |
| D01023 |
Tetrahydrozoline hydrochloride (JAN/USP); Tyzine (TN) |
(CI) unclassified |
| D01028 |
Ticlopidine hydrochloride (JP18/USP); Ticlid (TN) |
(P) CYP inhibition: CYP1A2 |
| D01051 |
Spiperone (JAN/USAN); Spiropitan (TN) |
(P) unclassified |
| D01077 |
Methylatropine nitrate (USAN); Atropine methonitrate (JAN/INN); Ekomine (TN) |
(P) unclassified |
| D01096 |
Hydroxyzine pamoate (JP18/USP); Atarax-P (TN); Vistaril pamoate (TN) |
(P) unclassified |
| D01097 |
Lazabemide hydrochloride (JAN/USAN); Tempium (TN) |
(P) unclassified |
| D01103 |
Trospium chloride (JAN/USP/INN); Spasmex (TN); Spasmoplex (TN) |
(P) unclassified |
| D01117 |
Mizolastine (JAN/INN); Mizollen (TN) |
(P) unclassified |
| D01118 |
Profenamine hydrochloride (JAN); Ethopropazine hydrochloride; Parkin (TN); Parsidol (TN) |
(P) unclassified |
| D01143 |
Isothipendyl hydrochloride (JAN); Andantol (TN) |
(P) unclassified |
| D01148 |
Tolterodine tartrate (JAN/USP); Detrol (TN); Detrusitol (TN) |
(P) Enzyme: CYP3A4 |
| D01153 |
Pazufloxacin (JAN/INN) |
(P) CYP inhibition: CYP1A2 |
| D01165 |
Piperidolate hydrochloride (JAN); Dactil (TN) |
(P) unclassified |
| D01172 |
Diphenylpyraline hydrochloride (JAN); Hispril (TN); Vena (TN) |
(P) unclassified |
| D01174 |
Pheniramine maleate (JAN/USP) |
(P) unclassified |
| D01177 |
Remifentanil hydrochloride (JAN/USAN); Ultiva (TN) |
(P) unclassified |
| D01179 |
Duloxetine hydrochloride (JAN/USP); Cymbalta (TN); Yentreve (TN) |
(P) Enzyme: CYP1A2 |
| D01192 |
Olopatadine hydrochloride (JP18/USP); Allelock (TN); Patanol (TN); Opatanol (TN) |
(P) unclassified |
| D01201 |
Tiemonium iodide (JAN/INN); Visceralgine (TN) |
(P) unclassified |
| D01205 |
Dexmedetomidine hydrochloride (JAN/USP); Igalmi (TN); Precedex (TN) |
(CI) Target: ADRA2A ADRA2B ADRA2C |
| D01207 |
Omeprazole sodium (USAN); Losec sodium (TN) |
(P) unclassified |
| D01224 |
Phenylpropanolamine hydrochloride (JAN/USP) |
(CI,P) Target: ADRA2A ADRA2B ADRA2C / CYP inhibition: CYP1A2 |
| D01227 |
Bosentan (USAN); Bosentan hydrate (JAN); Tracleer (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D01230 |
Flunitrazepam (JP18/USAN/INN); Rohypnol (TN) |
(P) unclassified |
| D01231 |
Piroheptine hydrochloride (JAN); Trimol (TN) |
(P) unclassified |
| D01235 |
Josamycin (JP18/USAN/INN); Leucomycin A3; JM |
(P) CYP inhibition: CYP3A4 |
| D01242 |
Promethazine teoclate (JAN/INN); Avomine (TN) |
(P) unclassified |
| D01245 |
Bromazepam (JP18/USAN/INN); Lectopam (TN) |
(P) unclassified |
| D01253 |
Clobazam (JAN/USAN/INN); Mystan (TN); Onfi (TN) |
(P) Enzyme: CYP3A4 |
| D01254 |
Tofisopam (JP18/INN); Emandaxin (TN) |
(P) unclassified |
| D01263 |
Ritodrine hydrochloride (JP18/USP); Yutopar (TN) |
(CI) unclassified |
| D01268 |
Cloxazolam (JP18/INN); Sepazon (TN) |
(P) unclassified |
| D01269 |
Solifenacin succinate (JAN/USAN/INN); Vesicare (TN) |
(P) Enzyme: CYP3A4 |
| D01276 |
Atazanavir sulfate (JAN/USAN); Reyataz (TN) |
(P) CYP inhibition: CYP3A4 |
| D01278 |
Oxazolam (JP18/INN); Serenal (TN) |
(P) unclassified |
| D01279 |
Flutoprazepam (JP18/INN); Restas (TN) |
(P) unclassified |
| D01286 |
Flutazolam (JAN/INN); Coreminal (TN) |
(P) unclassified |
| D01292 |
Medazepam (JP18/INN); Pamnace (TN) |
(P) unclassified |
| D01293 |
Ethyl loflazepate (JP18/INN); Meilax (TN) |
(P) Enzyme: CYP3A4 |
| D01295 |
Cinnarizine (JAN/USAN/INN) |
(P) unclassified |
| D01297 |
Pirenzepine hydrochloride (USAN) |
(P) unclassified |
| D01302 |
Hydralazine hydrochloride (JP18/USP); Apresoline (TN) |
(P) unclassified |
| D01307 |
Midodrine hydrochloride (JAN/USP); Pro-Amatine (TN) |
(CI) unclassified |
| D01315 |
Methylbenactyzium bromide (JP18/INN) |
(P) unclassified |
| D01316 |
Mexazolam (JAN/INN); Melex (TN) |
(P) Enzyme: CYP3A4 |
| D01317 |
Meclizine hydrochloride (JAN/USP); Meclizine dihydrochloride monohydrate; Antivert (TN) |
(P) unclassified |
| D01322 |
Troleandomycin (USAN/INN); Triacetyloleandomycin (JAN); TAO; Tao (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D01324 |
Mequitazine (JP18/INN); Kitazemin (TN) |
(P) unclassified |
| D01328 |
Clotiazepam (JP18/INN); Rize (TN) |
(P) unclassified |
| D01332 |
Ketotifen fumarate (JP18/USAN); Zaditen (TN) |
(P) unclassified |
| D01333 |
Urapidil (JP18/INN); Ebrantil (TN) |
(P) unclassified |
| D01336 |
Carbinoxamine maleate (JAN/USP); Clistin (TN); Karbinal er (TN) |
(P) unclassified |
| D01339 |
Midecamycin (JP18/INN); Medemycin (TN) |
(P) CYP inhibition: CYP3A4 |
| D01343 |
Dimethindene maleate (USAN); Dimetindene maleate (JAN); Forhistal maleate (TN) |
(P) unclassified |
| D01349 |
Pirbuterol hydrochloride (JAN/USAN) |
(CI) unclassified |
| D01354 |
Fludiazepam (JP18/INN); Erispan (TN) |
(P) unclassified |
| D01355 |
Tramadol hydrochloride (JP18/USP); Ultram (TN) |
(P) Enzyme: CYP3A4 |
| D01359 |
Etomidoline (JAN/INN); Smedolin (TN) |
(P) unclassified |
| D01360 |
Clenbuterol hydrochloride (JAN/USP); Spiropent (TN) |
(CI) unclassified |
| D01361 |
Erythromycin ethylsuccinate (JP18/USP); E.E.S. (TN); Eryped (TN); Erythrocin W (TN) |
(P) unclassified |
| D01362 |
Tulobuterol hydrochloride (JP18); Hokunalin (TN); Respacal (TN) |
(CI) unclassified |
| D01373 |
Formoterol fumarate (USP); Foradil (TN) |
(CI) unclassified |
| D01377 |
Prifinium bromide (JAN/INN); Padrin (TN) |
(P) unclassified |
| D01383 |
Meperidine hydrochloride (USP); Pethidine hydrochloride (JP18); Demerol (TN) |
(P) unclassified |
| D01386 |
Ephedrine hydrochloride (JP18/USP) |
(CI) Target: ADRA2A ADRA2B ADRA2C |
| D01390 |
Isoproterenol hydrochloride (USP); dl-Isoprenaline hydrochloride (JAN); Isuprel (TN); Proternol-S (TN) |
(CI) unclassified |
| D01399 |
Fentanyl citrate (JP18/USP); Abstral (TN); Fentora (TN); Lazanda (TN); Oralet (TN) |
(P) Enzyme: CYP3A4 |
| D01405 |
Norfenefrine hydrochloride (JAN); Zondel (TN) |
(CI) unclassified |
| D01408 |
Flurazepam hydrochloride (JP18); Flurazepam monohydrochloride; Dalmate (TN) |
(P) unclassified |
| D01428 |
Fenoterol hydrobromide (JAN); Berotec (TN) |
(CI) unclassified |
| D01429 |
Fosfluconazole (JAN/INN); Prodif (TN) |
(P) CYP inhibition: CYP3A4 |
| D01451 |
Scopolamine butylbromide (JP18); Butylscopolamine bromide; Buscopan (TN) |
(P) unclassified |
| D01453 |
Caffeine hydrate (JP18); Caffeine monohydrate |
(P) Enzyme: CYP1A2 |
| D01460 |
Homochlorcyclizine hydrochloride (JP18); Homochlorcyclizine dihydrochloride; SA 97 dihydrochloride; Homoclomin (TN) |
(P) unclassified |
| D01463 |
Diponium bromide (JAN/INN); Dipenine bromide |
(P) unclassified |
| D01477 |
Opipramol hydrochloride (JAN/USAN); Insidon (TN) |
(P) Target: HTR2A HTR2C |
| D01478 |
Ebastine (JP18/USAN/INN); Kestine (TN) |
(P) Enzyme: CYP3A4 |
| D01481 |
Dihydrocodeine phosphate (JP18); Dihydro (TN) |
(P) unclassified |
| D01482 |
Pipamperone hydrochloride (JAN) |
(P) unclassified |
| D01491 |
Butropium bromide (JP18/INN); Coliopan (TN) |
(P) unclassified |
| D01501 |
Isoniazid calcium pyruvinate (JAN); Pyruvic acid calcium isoniazid |
(P) unclassified |
| D01510 |
Dexamethasone metasulfobenzoate sodium (JAN); Dexamethazone metasulfobenzoate sodium; Dexapos; Santeson (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D01514 |
Etizolam (JP18/INN); Sedekopan (TN) |
(P) Enzyme: CYP3A4 |
| D01521 |
Pipethanate hydrochloride (JAN); Glymor (TN) |
(P) unclassified |
| D01531 |
Pipemidic acid hydrate (JP18); Karunomazin (TN) |
(P) CYP inhibition: CYP1A2 |
| D01538 |
Valethamate bromide (JAN); Shinmetane (TN) |
(P) unclassified |
| D01564 |
Rilmazafone hydrochloride hydrate (JP18); Rilmazafone hydrochloride dihydrate; Rilmazafone hydrochloride; Rhythmy (TN) |
(P) Enzyme: CYP3A4 |
| D01589 |
Mabuterol hydrochloride (JAN); Broncholin (TN) |
(CI) unclassified |
| D01593 |
Nimetazepam (JAN/INN); Erimin (TN) |
(P) unclassified |
| D01600 |
Diphenylpiperidinomethyldioxolan iodide (JAN); Anacolin; Gastrophyllin-A (TN) |
(P) unclassified |
| D01603 |
Bethanidine sulfate (JAN/USAN); Tenathan (TN) |
(P) Target: ADRA2A ADRA2B ADRA2C |
| D01615 |
Dexamethasone palmitate (JAN); Dexamethasone 21-palmitate; Limethason (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D01627 |
Diphenylpyraline teoclate (JAN); Piprinhydrinate; Plokon (TN) |
(P) unclassified |
| D01632 |
Dexamethasone dipropionate (USAN); Dexamethasone propionate (JAN); Hifmeta (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D01635 |
Methoxyphenamine hydrochloride (JAN); Phenamine (TN) |
(CI) unclassified |
| D01636 |
Midecamycin acetate (JP18); Miocamycin; Miocamycin (TN) |
(P) CYP inhibition: CYP3A4 |
| D01648 |
Hyoscyamine methylbromide (JAN) |
(P) unclassified |
| D01654 |
Bepotastine besylate (USAN); Bepotastine besilate (JP18); Bepreve (TN); Talion (TN) |
(P) unclassified |
| D01657 |
Lormetazepam (JAN/USAN/INN); Loramet (TN) |
(P) unclassified |
| D01699 |
Darifenacin hydrobromide (JAN/USAN); Enablex (TN) |
(P) Enzyme: CYP3A4 |
| D01713 |
Epinastine hydrochloride (JAN); Alesion (TN); Elestat (TN) |
(P) unclassified |
| D01717 |
Levocabastine hydrochloride (JAN/USP); Livostin (TN) |
(P) unclassified |
| D01744 |
Brotizolam (JP18/USAN/INN); Lendormin (TN) |
(P) Enzyme: CYP3A4 |
| D01748 |
Isoxsuprine hydrochloride (JP18/USP); Duvadilan (TN) |
(CI) unclassified |
| D01758 |
Haloxazolam (JP18/INN); Somelin (TN) |
(P) unclassified |
| D01773 |
Oxatomide (JAN/USAN/INN); Celtect (TN) |
(P) unclassified |
| D01782 |
Triprolidine hydrochloride (USP); Triprolidine hydrochloride hydrate (JAN); Venen (TN) |
(P) unclassified |
| D01786 |
Mebhydrolin napadisilate (JAN) |
(P) unclassified |
| D01801 |
Thonzylamine hydrochloride (JAN/USAN); Super anahist (TN) |
(P) unclassified |
| D01804 |
Cadralazine (JP18/INN); Cadral (TN) |
(P) unclassified |
| D01815 |
Oxapium iodide (JP18/INN); Espalexan (TN) |
(P) unclassified |
| D01832 |
Modafinil (JAN/USP/INN); Provigil (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP1A2 CYP3A4 |
| D01835 |
Clorprenaline hydrochloride (JAN/USAN) |
(CI) unclassified |
| D01871 |
Methixene hydrochloride (USAN); Metixene hydrochloride (JAN); Methixene hydrochloride hydrete; Trest (TN) |
(P) unclassified |
| D01875 |
Tiquizium bromide (JAN/INN); Thiaton (TN) |
(P) unclassified |
| D01879 |
Eptazocine hydrobromide (JAN); Sedapain (TN) |
(P) unclassified |
| D01888 |
Safrazine hydrochloride (JAN) |
(P) unclassified |
| D01898 |
Haloperidol decanoate (JAN/USP); Halomonth (TN) |
(CI,P) Enzyme: CYP3A4 |
| D01902 |
Fonazine mesylate (USAN); Dimetotiazine mesilate (JAN); Banistyl (TN) |
(P) Target: HTR2A HTR2C |
| D01929 |
Tiotropium bromide hydrate (JAN); Tiotropium bromide monohydrate; Spiriva (TN) |
(P) unclassified |
| D01946 |
Oxitropium bromide (JAN/INN); Tersigan (TN) |
(P) unclassified |
| D01948 |
Dexamethasone valerate (JAN); Dexamethasone 17-valerate; DV-17; Voalla ointment (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D01952 |
L-Methylephedrine hydrochloride (JAN) |
(CI) Target: ADRA2A ADRA2B ADRA2C |
| D01976 |
N-Methylscopolamine methylsulfate (JAN); Daipin (TN) |
(P) unclassified |
| D01978 |
Trimetoquinol hydrochloride; Tretoquinol; Inolin (TN) |
(CI) unclassified |
| D01980 |
Luliconazole (JAN/USAN/INN); Lulicon (TN); Luzu (TN) |
(P) CYP inhibition: CYP3A4 |
| D02002 |
Isoniazid sodium methanesulfonate hydrate (JAN); Isoniazid sodium methanesulfonate monohydrate; Isoniazid sodium methanesulfonate; IHMS; Neoiscotin (TN) |
(P) unclassified |
| D02004 |
Apomorphine hydrochloride (USP); Apomorphine hydrochloride hydrate (JAN); Apokyn (TN); Ixense (TN); Uprima (TN) |
(P) unclassified |
| D02009 |
Erythromycin lactobionate (JP18/USP); Erythrocin (TN) |
(P) unclassified |
| D02066 |
Isoproterenol sulfate (USP); Isoprenaline sulfate (JAN); Luf-Iso (TN); Medihaler-Iso (TN) |
(CI) unclassified |
| D02069 |
Atropine sulfate (JP18/USP); Ryjusea (TN) |
(P) unclassified |
| D02070 |
Homatropine methylbromide (USP); Equipin (TN) |
(P) unclassified |
| D02071 |
Scopolamine hydrobromide (USP); Scopolamine hydrobromide hydrate (JP18); Scopolamine hydrobromide trihydrate; Hysco (TN); Isopto hyoscine (TN) |
(P) unclassified |
| D02076 |
Brimonidine tartrate (JAN/USAN); Alphagan (TN) |
(CI) Target: ADRA2A ADRA2B ADRA2C |
| D02087 |
Moricizine hydrochloride (USP); Ethmozine (TN) |
(P) CYP induction: CYP1A2 |
| D02089 |
Buclizine hydrochloride (USAN); Vibazine (TN) |
(P) unclassified |
| D02090 |
Cyclizine lactate (BAN); Marezine (TN) |
(P) unclassified |
| D02091 |
Tripelennamine hydrochloride (USP); PBZ-SR (TN) |
(P) unclassified |
| D02093 |
Isoetharine hydrochloride (USP); BETA-2 (TN) |
(CI) unclassified |
| D02096 |
Fosphenytoin sodium (USP); Cerebyx (TN); Sesquient (TN) |
(P) CYP induction: CYP3A4 |
| D02101 |
Codeine phosphate (USP); Codeine phosphate hydrate (JP18) |
(P) unclassified |
| D02102 |
Methadone hydrochloride (JAN/USP); Dolophine hydrochloride (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D02103 |
Phenytoin sodium (USP); Phenytoin sodium for injection (JP18); Aleviatin (TN); Dilantin (TN) |
(P) unclassified |
| D02106 |
Arsenic trioxide (JP18/USAN); Trisenox (TN) |
(P) unclassified |
| D02109 |
dl-Methylephedrine hydrochloride (JP18); Methy-F (TN) |
(CI) Target: ADRA2A ADRA2B ADRA2C |
| D02111 |
Pentazocine lactate (USP); Talwin (TN) |
(P) unclassified |
| D02135 |
Levodopa and benserazide hydrochloride; Madopar (TN) |
(P) unclassified |
| D02147 |
Albuterol (USP); Salbutamol; Proventil (TN) |
(CI) unclassified |
| D02148 |
Phenindamine tartrate (USAN); Nolahist (TN) |
(P) unclassified |
| D02149 |
Epinephrine bitartrate (USP); Adrenaline bitartrate (JAN); Asmatane mist (TN); Medihaler-epi (TN) |
(CI) Target: ADRA2A ADRA2B ADRA2C |
| D02150 |
l-Isoprenaline hydrochloride (JP18); Proternol-L (TN) |
(CI) unclassified |
| D02151 |
Tulobuterol (JP18/INN); Atenos (TN); Hokunalin (TN) |
(CI) unclassified |
| D02174 |
Dexamethasone acetate (JAN/USP); Decadronal (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D02175 |
Compound oxycodone (JP18); Pavinal (TN) |
(P) Enzyme: CYP3A4 |
| D02184 |
Erythromycin stearate (JP18/USP); Bristamycin (TN) |
(P) unclassified |
| D02212 |
Ipratropium bromide (USP); Ipratropium bromide hydrate (JP18); Atrovent (TN) |
(P) unclassified |
| D02216 |
Ciprofloxacin hydrochloride (USP); Ciprofloxacin hydrochloride hydrate (JP18); Ciloxan (TN); Cipro (TN); Proquin XR (TN) |
(P) CYP inhibition: CYP1A2 |
| D02227 |
Pentazocine hydrochloride (JAN/USP); Sosegon (TN); Talacen (TN) |
(P) unclassified |
| D02234 |
Cyproheptadine hydrochloride (JP18/USP); Cyproheptadine hydrochloride sesquihydrate; Periactin (TN) |
(P) Target: HTR2A HTR2C |
| D02237 |
Guanethidine sulfate (USAN) |
(P) unclassified |
| D02245 |
Trimeprazine tartrate (USP); Alimemazine tartrate (JP18); Alimezine (TN) |
(P) unclassified |
| D02246 |
Biperiden hydrochloride (JP18/USP); Tasmolin (TN) |
(P) unclassified |
| D02247 |
Biperiden lactate (JAN/USP); Tasmolin (TN) |
(P) unclassified |
| D02249 |
Emedastine difumarate (JP18/USP); Daren (TN); Emadine (TN) |
(P) unclassified |
| D02260 |
Paroxetine hydrochloride hemihydrate (USP); Paroxetine hydrochloride hydrate (JP18); Paxil (TN) |
(P) unclassified |
| D02271 |
Morphine hydrochloride hydrate (JP18); Morphine hydrochloride trihydrate; Anpec (TN) |
(P) unclassified |
| D02281 |
Levalbuterol hydrochloride (USP); Xopenex (TN) |
(CI) unclassified |
| D02312 |
Methylene blue (USP); Methylthioninium chloride; Provayblue (TN) |
(P) CYP inhibition: CYP1A2 |
| D02327 |
Doxylamine succinate (USP); Decapryn (TN) |
(P) unclassified |
| D02349 |
Dipivefrin (USAN); Dipivefrine (INN) |
(CI) Target: ADRA2A ADRA2B ADRA2C |
| D02356 |
Verapamil (USAN/INN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D02359 |
Ritodrine (USAN/INN) |
(CI) unclassified |
| D02360 |
Sertraline (INN) |
(P) Enzyme: CYP3A4 |
| D02362 |
Paroxetine (USP/INN) |
(P) unclassified |
| D02363 |
Ketanserin (USAN/INN) |
(P) Target: HTR2A |
| D02372 |
Perospirone hydrochloride hydrate (JAN); Lullan (TN) |
(P) Target: HTR2A |
| D02388 |
Levonordefrin (USP); Corbadrine (INN); Neo-cobefrin (TN) |
(CI) Target: ADRA2A ADRA2B ADRA2C |
| D02396 |
Hexoprenaline sulfate (USAN); Delaprem (TN) |
(CI) unclassified |
| D02404 |
Procaterol hydrochloride (USAN); Pro-Air (TN) |
(CI) Enzyme: CYP3A4 |
| D02417 |
Flutropium bromide (JAN); Flutropium bromide monohydrate; Flubron (TN) |
(P) unclassified |
| D02419 |
Diphenhydramine salicylate (JAN) |
(P) unclassified |
| D02484 |
Artemether and lumefantrine; Coartem (TN) |
(P) unclassified |
| D02497 |
Fosamprenavir (INN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D02523 |
Erythromycin acistrate (USAN); Erasis (TN) |
(P) unclassified |
| D02524 |
Erythromycin gluceptate (USP); Erythromycin glucoheptonate; Ilotycin gluceptate (TN) |
(P) unclassified |
| D02525 |
Erythromycin propionate (USAN) |
(P) unclassified |
| D02535 |
Timepidium bromide hydrate (JP18); Sesden (TN) |
(P) unclassified |
| D02537 |
Dronedarone (INN) |
(CI) unclassified |
| D02554 |
Rifaximin (JAN/USAN/INN); Xifaxan (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D02555 |
Posaconazole (JAN/USAN/INN); Noxafil (TN) |
(P) CYP inhibition: CYP3A4 |
| D02559 |
Toloxatone (INN); Humoryl (TN) |
(P) unclassified |
| D02560 |
Brofaromine (INN); Consonar (TN) |
(P) unclassified |
| D02561 |
Moclobemide (USAN/INN); Aurorix (TN) |
(P) unclassified |
| D02562 |
Rasagiline mesylate (USAN); Rasagiline mesilate (JAN); Azilect (TN) |
(P) Enzyme: CYP1A2 |
| D02563 |
Befloxatone (INN) |
(P) unclassified |
| D02564 |
Pargyline hydrochloride (USAN); Eutonyl (TN) |
(P) unclassified |
| D02567 |
Escitalopram oxalate (JAN/USP); Lexapro (TN) |
(P) Enzyme: CYP3A4 |
| D02579 |
Iproniazid (INN) |
(P) unclassified |
| D02580 |
Isocarboxazid (INN); Marplan (TN) |
(P) unclassified |
| D02581 |
Cimoxatone (INN) |
(P) unclassified |
| D02591 |
Dexamethasone acefurate (USAN/INN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D02592 |
Dexamethasone beloxil (USAN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D02599 |
Orphenadrine hydrochloride; Disipal (TN) |
(P) unclassified |
| D02600 |
Demoxepam (USAN/INN) |
(P) unclassified |
| D02611 |
Phenoperidine (INN) |
(P) unclassified |
| D02614 |
Denopamine (JAN/INN); Kalgut (TN) |
(CI) unclassified |
| D02691 |
Somatropin (USP/INN); Somatropin (genetical recombination) (JAN); Human growth hormone (JAN); Asellacrin (TN); Humatrope (TN); Nutropin (TN); Omnitrope (TN) |
(P) unclassified |
| D02702 |
Talibegron hydrochloride (USAN) |
(CI) unclassified |
| D02732 |
Pranlukast hydrate (JP18); Onon (TN) |
(P) Enzyme: CYP3A4 |
| D02748 |
Peginterferon alfa-2b (USAN/INN); Peginterferon alfa-2b (genetical recombination) (JAN); Pegintron (TN); Sylatron (TN) |
(P) CYP inhibition: CYP1A2 |
| D02760 |
Acrivastine (USAN/INN) |
(P) unclassified |
| D02770 |
Adinazolam (USAN/INN) |
(P) unclassified |
| D02771 |
Adinazolam mesylate (USAN) |
(P) unclassified |
| D02774 |
Adrenalone (USAN/INN) |
(CI) unclassified |
| D02861 |
Indinavir sulfate ethanolate (JAN); Crixivan (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D02867 |
Fosamprenavir calcium hydrate (JAN); Lexiva (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D02876 |
Alvameline maleate (USAN) |
(P) unclassified |
| D02901 |
Amidephrine mesylate (USAN); Amidefrine mesilate (INN) |
(CI) unclassified |
| D02910 |
Amiodarone (USAN/INN) |
(CI) Enzyme: CYP3A4 |
| D02941 |
Anileridine (USP/INN) |
(P) unclassified |
| D02942 |
Anileridine hydrochloride (USP); Leritine (TN) |
(P) unclassified |
| D02950 |
Antazoline phosphate (USP) |
(P) unclassified |
| D02968 |
Aprepitant (JAN/USP/INN); Aponvie (TN); Emend (TN); Cinvanti (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 / CYP induction: CYP3A4 |
| D02976 |
Arbutamine hydrochloride (USAN); Genesa (TN) |
(CI) unclassified |
| D02981 |
Arformoterol tartrate (USAN); Brovana (TN) |
(CI) unclassified |
| D03083 |
Bentazepam (USAN/INN) |
(P) unclassified |
| D03087 |
Benzetimide hydrochloride (USAN); Dioxatrine (TN) |
(P) unclassified |
| D03098 |
Berythromycin (USAN/INN); Erythromycin B |
(P) unclassified |
| D03106 |
Bexarotene (JAN/USAN/INN); Targretin (TN) |
(P) unclassified |
| D03156 |
Brifentanil hydrochloride (USAN) |
(P) unclassified |
| D03165 |
Bromocriptine (USAN/INN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D03166 |
Bromodiphenhydramine hydrochloride (USP); Bromazine hydrochloride; Bromanyl (TN) |
(P) unclassified |
| D03195 |
Butopamine (USAN/INN) |
(CI) unclassified |
| D03197 |
Butorphanol (USAN/INN) |
(P) unclassified |
| D03230 |
Insulin human (USP/INN); Insulin human (genetical recombination) (JP18); Insulin human (biosynthesis) (JAN); Insulin human (synthesis) (JAN); Humulin (TN) |
(P) CYP induction: CYP1A2 |
| D03239 |
Ladostigil tartrate (USAN) |
(P) unclassified |
| D03248 |
Clorgiline (INN); Clorgyline |
(P) unclassified |
| D03250 |
Insulin glargine (USAN/INN); Insulin glargine (genetical recombination) (JP18); Insulin glargine (genetical recombination) [Insulin glargin biosimilar 1] (JAN); Insulin glargine (genetical recombination) [Insulin glargin biosimilar 2] (JAN); Insulin glargine-yfgn; Lantus (TN) |
(P) CYP induction: CYP1A2 |
| D03264 |
Mazaticol hydrochloride hydrate (JAN); Mazaticol hydrochloride; Pentona (TN) |
(P) unclassified |
| D03274 |
Chlorpromazine hibenzate (JAN); Contomin (TN) |
(P) Target: ADRA2A ADRA2B ADRA2C HTR2A HTR2C |
| D03276 |
Profenamine hibenzate (JAN); Parkin (TN) |
(P) unclassified |
| D03285 |
Diphenhydramine tannate (JP18); Restamin A (TN) |
(P) unclassified |
| D03290 |
Promethazine methylenedisalicylate (JAN); Pyrethia (TN) |
(P) unclassified |
| D03360 |
Diphenhydramine laurylsulfate (JAN); Vena (TN) |
(P) unclassified |
| D03365 |
Nicotine (USP); Habitrol (TN) |
(P) CYP induction: CYP1A2 |
| D03402 |
Carbuterol hydrochloride (USAN) |
(CI) unclassified |
| D03405 |
Carfentanil citrate (USAN) |
(P) unclassified |
| D03409 |
Caroxazone (USAN/INN) |
(P) unclassified |
| D03444 |
Opium (USP); Opium, powdered (JP18); Diluted opium powder (JP18) |
(P) unclassified |
| D03445 |
Opium alkaloids hydrochlorides (JP18); Pan opin (TN) |
(P) unclassified |
| D03475 |
Chlorpheniramine polistirex (USAN) |
(P) unclassified |
| D03502 |
Cimaterol (USAN/INN) |
(CI) unclassified |
| D03503 |
Cimetidine hydrochloride (USP) |
(P) CYP inhibition: CYP3A4 |
| D03535 |
Clemastine (USAN) |
(P) unclassified |
| D03562 |
Clorazepate monopotassium (USAN) |
(P) unclassified |
| D03579 |
Codeine polistirex (USAN) |
(P) unclassified |
| D03580 |
Codeine sulfate (USP); Codeine sulfate trihydrate |
(P) unclassified |
| D03587 |
Colterol mesylate (USAN) |
(CI) unclassified |
| D03618 |
Cyclazocine (USAN/INN) |
(P) unclassified |
| D03621 |
Cyclizine (INN) |
(P) unclassified |
| D03622 |
Cyclizine hydrochloride (USP) |
(P) unclassified |
| D03631 |
Cyprazepam (USAN/INN) |
(P) unclassified |
| D03654 |
Darifenacin (USAN/INN) |
(P) Enzyme: CYP3A4 |
| D03656 |
Darunavir (USAN/INN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D03658 |
Dasatinib (JAN/INN) |
(P) Enzyme: CYP3A4 |
| D03664 |
Debrisoquin sulfate (USAN); Declinax (TN) |
(P) unclassified |
| D03669 |
Deferasirox (JAN/USAN/INN); Exjade (TN); Jadenu (TN) |
(P) CYP inhibition: CYP1A2 / CYP induction: CYP3A4 |
| D03693 |
Desloratadine (JAN/USP/INN); Clarinex (TN) |
(P) unclassified |
| D03702 |
Detomidine hydrochloride (USAN) |
(CI) Target: ADRA2A ADRA2B ADRA2C |
| D03704 |
Dexbrompheniramine maleate (USP); Disomer (TN) |
(P) unclassified |
| D03711 |
Dexetimide (USAN/INN); (+)-Benzetimide |
(P) unclassified |
| D03731 |
Selegiline (USAN/INN); Emsam (TN) |
(P) Enzyme: CYP3A4 |
| D03733 |
Mofegiline hydrochloride (USAN) |
(P) unclassified |
| D03737 |
Dextofisopam (USAN/INN) |
(P) unclassified |
| D03783 |
Oxycodone terephthalate (USP) |
(P) Enzyme: CYP3A4 |
| D03814 |
Atropine methylbromide (JAN) |
(P) unclassified |
| D03824 |
Dihexyverine hydrochloride (USAN) |
(P) unclassified |
| D03825 |
Dihydrocodeine bitartrate (USP) |
(P) unclassified |
| D03833 |
Indinavir (USAN); Indinavir hydrate |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D03835 |
Fosamprenavir calcium (USAN); Lexiva (TN); Telzir (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D03837 |
Fosamprenavir sodium (USAN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D03854 |
Diphenhydramine citrate (USP) |
(P) unclassified |
| D03855 |
Pethidine hydrochloride and levallorphan tartrate; Pethilorfan (TN) |
(P) unclassified |
| D03863 |
Opium alkaloids and atropine (JP18); Opium alkaloids hydrochloride and atropine sulfate hydrate; Opiato (TN) |
(P) unclassified |
| D03866 |
Opium alkaloids and scopolamine (JP18); Weak opium alkaloids and scopolamine (JP18); Opium alkaloids hydrochloride and scopolamine hydrobromide hydrate; Opisco (TN) |
(P) unclassified |
| D03879 |
Dobutamine (USAN/INN) |
(CI) unclassified |
| D03880 |
Dobutamine lactobionate (USAN) |
(CI) unclassified |
| D03881 |
Dobutamine tartrate (USAN) |
(CI) unclassified |
| D03891 |
Dopexamine (USAN/INN) |
(CI) Target: DRD4 |
| D03892 |
Dopexamine hydrochloride (USAN); Dopacard (TN) |
(CI) Target: DRD4 |
| D03914 |
Dronedarone hydrochloride (USP); Multaq (TN) |
(CI) unclassified |
| D03994 |
Endralazine mesylate (USAN); Endralazine monomethanesulfonate; Migranal (TN) |
(P) unclassified |
| D04018 |
Ephedrine sulfate (USP); Akovaz (TN); Corphedra (TN); Emerphed (TN) |
(CI) Target: ADRA2A ADRA2B ADRA2C |
| D04024 |
Lapatinib ditosylate (USAN); Lapatinib tosilate hydrate (JAN); Lapatinib ditosylate monohydrate; Tykerb (TN); Tyverb (TN) |
(P) Enzyme: CYP3A4 |
| D04034 |
Chlorpromazine phenolphthalinate (JAN); Wintermin (TN) |
(P) Target: ADRA2A ADRA2B ADRA2C HTR2A HTR2C |
| D04052 |
Epinephrine and lidocaine hydrochloride; Adrenaline and lidocaine hydrochloride; Xylocaine (TN) |
(CI,P) Enzyme: CYP1A2 CYP3A4 |
| D04054 |
Erythromycin salnacedin (USAN); Erythromycin salnacedin dihydrate |
(P) unclassified |
| D04057 |
Esoxybutynin chloride (USAN) |
(P) unclassified |
| D04087 |
Ethybenztropine (USAN); Etybenzatropine (INN); Panolid (TN) |
(P) unclassified |
| D04092 |
Etryptamine acetate (USAN) |
(P) unclassified |
| D04112 |
Etravirine (JAN/USAN/INN); Intelence (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D04116 |
Eucatropine hydrochloride (USP XXXII) |
(P) unclassified |
| D04157 |
Fenoterol (USAN/INN) |
(CI) unclassified |
| D04248 |
Fosazepam (USAN/INN) |
(P) unclassified |
| D04265 |
Reserpine, hydralazine hydrochloride and hydrochlorothiazide |
(P) unclassified |
| D04266 |
Benzylhydrochlorothiazide, Reserpine and Carbazochrome; Behyd RA (TN) |
(P) unclassified |
| D04382 |
Guanethidine monosulfate (USP); Guanethidine sulfate (JP18); Ismelin (TN) |
(P) unclassified |
| D04386 |
Guanoclor sulfate (USAN); Vatensol (TN) |
(P) unclassified |
| D04398 |
Guanoxabenz (USAN/INN) |
(P) unclassified |
| D04399 |
Guanoxan sulfate (USAN); Envacar (TN) |
(P) unclassified |
| D04458 |
Hydralazine polistirex (USAN) |
(P) unclassified |
| D04475 |
Insulin aspart (USP/INN); Insulin aspart (genetical recombination) (JP18); Insulin aspart (genetical recombination) [Insulin aspart biosimilar 1] (JAN); Insulin X 14; Insulin aspart-szjj; nsulin aspart-xjhz; Merilog (TN); NovoRapid (TN); Novolog (TN); Kirsty (TN) |
(P) CYP induction: CYP1A2 |
| D04477 |
Insulin lispro (USP/INN); Insulin lispro (genetical recombination) (JAN); Insulin lispro (genetical recombination) [Insulin lispro Biosimilar 1] (JAN); Insulin lispro-aabc; Humalog (TN); Lyumjev (TN) |
(P) CYP induction: CYP1A2 |
| D04479 |
Hyoscyamine hydrobromide (USP) |
(P) unclassified |
| D04494 |
Icotidine (USAN) |
(P) unclassified |
| D04531 |
Indoramin (USAN/INN) |
(P) unclassified |
| D04532 |
Indoramin hydrochloride (USAN) |
(P) unclassified |
| D04539 |
Insulin detemir (USAN/INN); Insulin detemir (genetical recombination) (JAN); Levemir (TN) |
(P) CYP induction: CYP1A2 |
| D04540 |
Insulin glulisine (USAN/INN); Insulin glulisine (genetical recombination) (JAN); Apidra (TN) |
(P) CYP induction: CYP1A2 |
| D04547 |
Insulin, isophane (USP); Isophane insulin human (genetical recombination) injectable aqueous suspension (JP18); Isophane insulin (aqueous suspension) (JAN); Humalog PEN (TN) |
(P) CYP induction: CYP1A2 |
| D04549 |
Insulin zinc, extended (USP); Ultralente iletin (TN) |
(P) CYP induction: CYP1A2 |
| D04550 |
Insulin zinc, prompt (USP); Semilente iletin (TN) |
(P) CYP induction: CYP1A2 |
| D04551 |
Insulin zinc (USP); Lente iletin (TN) |
(P) CYP induction: CYP1A2 |
| D04625 |
Isoetharine (USP); Isoetarine (INN) |
(CI) unclassified |
| D04626 |
Isoetharine mesylate (USP); Bronkometer (TN) |
(CI) unclassified |
| D04641 |
Istradefylline (JAN/USAN/INN); Nourianz (TN); Nouriast (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D04649 |
Ketazocine (USAN/INN); Ketocyclazocine |
(P) unclassified |
| D04650 |
Ketazolam (USAN/INN) |
(P) unclassified |
| D04666 |
Lanreotide acetate (JAN/USAN); Somatuline (TN) |
(P) unclassified |
| D04681 |
Lazabemide (USAN/INN) |
(P) unclassified |
| D04701 |
Levalbuterol sulfate (USAN) |
(CI) unclassified |
| D04703 |
Levalbuterol tartrate (USAN); Xopenex HFA (TN) |
(CI) unclassified |
| D04708 |
Levdobutamine lactobionate (USAN) |
(CI) unclassified |
| D04716 |
Levomethadyl acetate (USAN); Levacetylmethadol (INN) |
(P) Enzyme: CYP3A4 |
| D04721 |
Levotofisopam (USAN/INN) |
(P) unclassified |
| D04749 |
Lithium citrate (USP); Lithonate (TN) |
(P) unclassified |
| D04750 |
Lithium hydroxide (USP) |
(P) unclassified |
| D04764 |
Lofentanil oxalate (USAN) |
(P) unclassified |
| D04765 |
Lofexidine hydrochloride (USAN); Lucemyra (TN) |
(CI) Target: ADRA2A ADRA2B ADRA2C |
| D04768 |
Lonafarnib (JAN/USAN/INN); Zokinvy (TN) |
(P) unclassified |
| D04813 |
Lidocaine hydrochloride and epinephrine bitartrate; Lidocaine hydrochloride and adrenaline bitartrate; Ora (TN); Lidosite (TN) |
(P) Enzyme: CYP1A2 CYP3A4 |
| D04868 |
Mebeverine hydrochloride (USAN) |
(P) unclassified |
| D04882 |
Medazepam hydrochloride (USAN); Nobrium (TN) |
(P) unclassified |
| D04883 |
Medetomidine hydrochloride (USAN) |
(CI) Target: ADRA2A ADRA2B ADRA2C |
| D04924 |
Meptazinol hydrochloride (USAN) |
(P) unclassified |
| D04954 |
Metaproterenol polistirex (USAN) |
(CI) unclassified |
| D04973 |
Methadyl acetate (USAN); Acetylmethadol (INN) |
(P) unclassified |
| D05024 |
Mibefradil dihydrochloride (USAN); Posicor (TN) |
(P) CYP inhibition: CYP1A2 |
| D05028 |
Midazolam maleate (USAN) |
(P) Enzyme: CYP3A4 |
| D05033 |
Milacemide hydrochloride (USAN) |
(P) unclassified |
| D05037 |
Trimetoquinol hydrochloride hydrate (JP18); Tretoquinol hydrate; Caluyon (TN) |
(CI) unclassified |
| D05039 |
Minaprine (USAN/INN); Cantor (TN) |
(P) unclassified |
| D05040 |
Minaprine hydrochloride (USAN) |
(P) unclassified |
| D05048 |
Mirfentanil hydrochloride (USAN) |
(P) unclassified |
| D05077 |
Moricizine (USAN); Moracizine (INN) |
(P) CYP induction: CYP1A2 |
| D05087 |
Moxonidine (USAN/INN); Cynt (TN) |
(P) Target: ADRA2A ADRA2B ADRA2C |
| D05154 |
Nexeridine hydrochloride (USAN) |
(P) unclassified |
| D05156 |
Nicotine bitartrate (USAN); Nicotine bitartrate dihydrate |
(P) CYP induction: CYP1A2 |
| D05157 |
Nicotine polacrilex (USP); Nicorette (TN) |
(P) CYP induction: CYP1A2 |
| D05196 |
Noberastine (USAN/INN) |
(P) unclassified |
| D05206 |
Norepinephrine bitartrate (USP); Levophed (TN) |
(CI) Target: ADRA2A ADRA2B ADRA2C |
| D05217 |
Ocfentanil hydrochloride (USAN) |
(P) unclassified |
| D05259 |
Omeprazole magnesium (USP); Prilosec OTC (TN) |
(P) unclassified |
| D05261 |
Omeprazole sodium injection (JAN); Omeprazole sodium hydrate; Omepral (TN) |
(P) unclassified |
| D05276 |
Pirenzepine hydrochloride hydrate (JP18); Gastrozepin (TN) |
(P) unclassified |
| D05277 |
Formoterol fumarate hydrate (JP18); Formoterol fumarate dihydrate; Atock (TN); Foradil (TN) |
(CI) unclassified |
| D05312 |
Oxycodone (USAN/INN) |
(P) Enzyme: CYP3A4 |
| D05340 |
Paliperidone palmitate (JAN/USAN); Xeplion (TN); Trevicta (TN); Invega sustenna (TN); Invega trinza (TN) |
(CI) Target: HTR2A |
| D05351 |
Josamycin propionate (JP18); Josamy (TN) |
(P) CYP inhibition: CYP3A4 |
| D05366 |
Procaterol hydrochloride hydrate (JP18); Meptin (TN) |
(CI) Enzyme: CYP3A4 |
| D05374 |
Paroxetine hydrochloride (USP); Paxil (TN) |
(P) unclassified |
| D05375 |
Paroxetine mesylate (USAN); Brisdelle (TN); Pexeva (TN) |
(P) unclassified |
| D05382 |
Pazufloxacin mesilate (JP18); Pazufloxacin methanesulfonate; Pasil (TN) |
(P) CYP inhibition: CYP1A2 |
| D05461 |
Enoxacin hydrate (JP18) |
(P) CYP inhibition: CYP1A2 |
| D05462 |
Oxycodone hydrochloride hydrate (JP18) |
(P) Enzyme: CYP3A4 |
| D05466 |
Phenylpropanolamine polistirex (USAN) |
(CI,P) Target: ADRA2A ADRA2B ADRA2C / CYP inhibition: CYP1A2 |
| D05476 |
Picumeterol fumarate (USAN) |
(CI) unclassified |
| D05482 |
Pinacidil (USAN); Pinacidil hydrate; Pindac (TN) |
(P) unclassified |
| D05606 |
Prenalterol hydrochloride (USAN) |
(CI) unclassified |
| D05632 |
Propoxyphene napsylate (USAN); Darvon-N (TN) |
(P) unclassified |
| D05648 |
Pseudoephedrine polistirex (USAN); Pseudo-12 (TN) |
(CI) Target: ADRA2A ADRA2B ADRA2C |
| D05649 |
Pseudoephedrine sulfate (USP); Afrinol (TN) |
(CI) Target: ADRA2A ADRA2B ADRA2C |
| D05660 |
Pyrilamine maleate (USP); Pymafed (TN) |
(P) unclassified |
| D05691 |
Ractopamine hydrochloride (USP) |
(CI) unclassified |
| D05705 |
Rauwolfia serpentina (USP); Rauwolfia extract; Himolfia (TN) |
(P) unclassified |
| D05710 |
Reclazepam (USAN/INN) |
(P) unclassified |
| D05718 |
Reproterol hydrochloride (USAN) |
(CI) unclassified |
| D05730 |
Rimiterol hydrobromide (USAN) |
(CI) unclassified |
| D05742 |
Rocastine hydrochloride (USAN) |
(P) unclassified |
| D05768 |
Rotigotine (JAN/USAN/INN); Neupro (TN) |
(P) unclassified |
| D05775 |
Rufinamide (JAN/USP/INN); Banzel (TN) |
(P) unclassified |
| D05792 |
Salmeterol (USAN/INN) |
(CI) Enzyme: CYP3A4 |
| D05832 |
Sibenadet hydrochloride (USAN); Viozan (TN) |
(CI) unclassified |
| D05879 |
Solabegron hydrochloride (USAN) |
(CI) unclassified |
| D05928 |
Stiripentol (JAN/USAN/INN); Diacomit (TN) |
(P) Enzyme: CYP1A2 CYP3A4 / CYP inhibition: CYP1A2 CYP3A4 |
| D05938 |
Sufentanil (USAN/INN) |
(P) unclassified |
| D05942 |
Sulazepam (USAN/INN) |
(P) unclassified |
| D06007 |
Tapentadol (USAN/INN) |
(P) unclassified |
| D06021 |
Tecastemizole (USAN/INN) |
(P) unclassified |
| D06063 |
Temelastine (USAN/INN) |
(P) unclassified |
| D06147 |
Tilidine hydrochloride (USAN); Valoron (TN) |
(P) unclassified |
| D06208 |
Trefentanil hydrochloride (USAN) |
(P) unclassified |
| D06231 |
Triflubazam (USAN/INN) |
(P) unclassified |
| D06234 |
Trimazosin hydrochloride (USAN); Trimazosin hydrochloride monohydrate |
(P) unclassified |
| D06246 |
Tripelennamine citrate; PBZ (TN) |
(P) unclassified |
| D06268 |
Trimeperidine (INN) |
(P) unclassified |
| D06273 |
Imidafenacin (JAN/INN); Uritos (TN); Staybla (TN) |
(P) Enzyme: CYP3A4 |
| D06342 |
Xorphanol mesylate (USAN) |
(P) unclassified |
| D06344 |
Xylazine hydrochloride (USP); Rompun (TN) |
(CI) Target: ADRA2A ADRA2B ADRA2C |
| D06374 |
Zinterol hydrochloride (USAN) |
(CI) unclassified |
| D06394 |
Dabuzalgron hydrochloride (USAN) |
(CI) unclassified |
| D06405 |
Nalfurafine hydrochloride (JAN/USAN) |
(P) Enzyme: CYP3A4 |
| D06413 |
Nilotinib hydrochloride hydrate (JAN); Nilotinib monohydrochloride monohydrate; Tasigna (TN) |
(P) Enzyme: CYP3A4 |
| D06414 |
Dasatinib (USAN); Dasatinib hydrate (JAN); Sprycel (TN) |
(P) Enzyme: CYP3A4 |
| D06478 |
Darunavir ethanolate (JAN); Prezista (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D06499 |
Opium tincture (JP18) |
(P) unclassified |
| D06552 |
Alcaftadine (JAN/USAN/INN); Lastacaft (TN) |
(P) unclassified |
| D06597 |
Fosaprepitant dimeglumine (USAN); Fosaprepitant meglumine (JAN); Proemend (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 / CYP induction: CYP3A4 |
| D06623 |
Olanzapine pamoate (USAN); Olanzapine pamoate monohydrate; Zyprexa (TN) |
(P) Enzyme: CYP1A2 / Target: DRD4 HTR2A HTR2C |
| D07073 |
Dexamethasone cipecilate (JAN/INN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D07076 |
Camylofin (INN); Anafortan (TN) |
(P) unclassified |
| D07077 |
Ambrisentan (JAN/INN); Letairis (TN); Volibris (TN) |
(P) unclassified |
| D07099 |
Cimetropium bromide (JAN/INN); Alginor (TN) |
(P) unclassified |
| D07122 |
Alfentanil (INN); Rapifen (TN) |
(P) unclassified |
| D07125 |
Alimemazine (INN); Trimeprazine (BAN); Repeltin (TN) |
(P) unclassified |
| D07132 |
Buprenorphine (JAN/INN); Temgesic (TN) |
(P) Enzyme: CYP3A4 |
| D07148 |
Oxedrine (BAN); (+/-)-Synephrine |
(CI) unclassified |
| D07166 |
Methoserpidine (INN) |
(P) unclassified |
| D07167 |
Bietaserpine (prop.INN) |
(P) unclassified |
| D07168 |
Tolonidine (INN) |
(P) unclassified |
| D07169 |
Guanazodine (INN) |
(P) unclassified |
| D07170 |
Dihydralazine (INN) |
(P) unclassified |
| D07171 |
Sitaxentan (USAN/INN) |
(P) unclassified |
| D07195 |
Chloropyramine (INN) |
(P) unclassified |
| D07197 |
Bamipine (INN) |
(P) unclassified |
| D07198 |
Chlorphenoxamine (INN) |
(P) unclassified |
| D07226 |
Fesoterodine (INN) |
(P) Enzyme: CYP3A4 |
| D07285 |
Nicomorphine (INN) |
(P) unclassified |
| D07286 |
Diamorphine (BAN); Heroin; Diacetylmorphine |
(P) unclassified |
| D07287 |
Dextromoramide (BAN) |
(P) unclassified |
| D07288 |
Piritramide (INN); Dipidolor (TN) |
(P) unclassified |
| D07289 |
Bezitramide (INN); Burgodin (TN) |
(P) unclassified |
| D07301 |
Phenglutarimide (INN) |
(P) unclassified |
| D07302 |
Bornaprine (INN) |
(P) unclassified |
| D07303 |
Tropatepine (INN) |
(P) unclassified |
| D07314 |
Pinazepam (INN); Domar (TN) |
(P) unclassified |
| D07315 |
Camazepam (INN) |
(P) unclassified |
| D07326 |
Loprazolam (INN); Dormonoct (TN) |
(P) unclassified |
| D07327 |
Doxefazepam (INN) |
(P) unclassified |
| D07328 |
Cinolazepam (INN); Gerodorm (TN) |
(P) unclassified |
| D07337 |
Nialamide (INN); Niamid (TN) |
(P) unclassified |
| D07338 |
Iproclozide (INN) |
(P) unclassified |
| D07377 |
Bambuterol (INN) |
(CI) unclassified |
| D07398 |
Chlorphenamine (INN); Chlorpheniramine; Clofeniramina (TN) |
(P) unclassified |
| D07402 |
Levocetirizine (USAN/INN); Xazal (TN) |
(P) Enzyme: CYP3A4 |
| D07404 |
Deptropine (INN) |
(P) unclassified |
| D07406 |
Pimethixene (INN); Calmixene (TN) |
(P) unclassified |
| D07407 |
Rupatadine (USAN/INN) |
(P) Enzyme: CYP3A4 |
| D07435 |
Papaveretum (BAN); Omnopon (TN) |
(P) unclassified |
| D07458 |
Antazoline (INN) |
(P) unclassified |
| D07459 |
Antazoline hydrochloride; Phenazolinum (TN) |
(P) unclassified |
| D07461 |
Apraclonidine (INN); Iopidine (TN) |
(CI) Target: ADRA2A ADRA2B ADRA2C |
| D07463 |
Arformoterol (INN) |
(CI) unclassified |
| D07471 |
Atazanavir (INN); Reyataz (TN) |
(P) CYP inhibition: CYP3A4 |
| D07482 |
Azatadine (INN) |
(P) unclassified |
| D07483 |
Azelastine (INN); Optivar (TN) |
(P) unclassified |
| D07489 |
Bambuterol hydrochloride; Bambec (TN) |
(CI) unclassified |
| D07492 |
Bamipine dihydrochloride; Soventol (TN) |
(P) unclassified |
| D07493 |
Bamipine lactate; Soventol (TN) |
(P) unclassified |
| D07511 |
Benzatropine (INN); Benztropine |
(P) unclassified |
| D07513 |
Benzetimide (INN); Spasmental [veterinary] (TN) |
(P) unclassified |
| D07534 |
Bitolterol (INN) |
(CI) unclassified |
| D07538 |
Bosentan (INN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D07540 |
Brimonidine (INN) |
(CI) Target: ADRA2A ADRA2B ADRA2C |
| D07543 |
Brompheniramine (INN); Brotane (TN) |
(P) unclassified |
| D07547 |
Buclizine (INN); Buclina (TN) |
(P) unclassified |
| D07560 |
Adrenalone hydrochloride; Stryphnasal (TN) |
(CI) unclassified |
| D07564 |
Allopurinol sodium; Aloprim (TN) |
(P) CYP inhibition: CYP1A2 |
| D07583 |
Phenytoin and phenobarbital; Aleviatin with phenobarbital (TN) |
(P) unclassified |
| D07595 |
Fosphenytoin sodium hydrate (JAN); Fostoin (TN) |
(P) CYP induction: CYP3A4 |
| D07603 |
Caffeine citrate (USP); Cafcit (TN) |
(P) Enzyme: CYP1A2 |
| D07617 |
Carbinoxamine (INN) |
(P) unclassified |
| D07620 |
Carfentanil (INN) |
(P) unclassified |
| D07662 |
Cetirizine (INN); Cetiderm (TN) |
(P) unclassified |
| D07679 |
Chloropyramine hydrochloride; Avapena (TN) |
(P) unclassified |
| D07684 |
Chlorphenoxamine hydrochloride; Allergex (TN) |
(P) unclassified |
| D07702 |
Ciprofloxacin lactate; Ciproxin (TN) |
(P) CYP inhibition: CYP1A2 |
| D07710 |
Clarithromycin lactobionate; Klacid (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D07713 |
Clenbuterol (INN); Contraspasmin (TN); Planipart [veterinary] (TN) |
(CI) unclassified |
| D07714 |
Climazolam (INN); Climasol [veterinary] (TN) |
(P) unclassified |
| D07734 |
Cinnarizine dihydrochloride; Celenid (TN) |
(P) unclassified |
| D07740 |
Codeine hydrochloride; Bisoltus (TN) |
(P) unclassified |
| D07759 |
Cyclopentolate (INN); Bell Pentolate (TN) |
(P) unclassified |
| D07765 |
Cyproheptadine (INN); Ciprovit (TN) |
(P) Target: HTR2A HTR2C |
| D07784 |
Delorazepam (INN); Dadumir (TN) |
(P) unclassified |
| D07790 |
Deptropine citrate |
(P) unclassified |
| D07795 |
Detomidine (INN) |
(CI) Target: ADRA2A ADRA2B ADRA2C |
| D07796 |
Dexamethasone 21-acetate; Dexamethasone acetate anhydrous; Decaject-L.A. (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D07797 |
Dexamethasone isonicotinate; Dexamethasone 21-isonicotinate; Voren [veterinary] (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D07798 |
Dexamethasone sodium hemisulfate; Dexamethasone 21-sodium sulfate |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D07799 |
Dexamethasone 21-tebutate; Dexamethasone tertiary butyl acetate; Dexamedium [veterinary] (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D07800 |
Dexamethasone 21-valerate; Voalla (TN); Zalucs (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D07801 |
Dexamethasone phenylpropionate; Dexafort [veterinary] (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D07802 |
Dexamethasone phosphate; Decadron-phosphate (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D07803 |
Dexchlorpheniramine (INN); d-Chloropheniramine; Dapriton (TN) |
(P) unclassified |
| D07804 |
Dexetimide hydrochloride; Tremblex (TN) |
(P) unclassified |
| D07808 |
Dextromoramide tartrate; Palfium (TN) |
(P) unclassified |
| D07809 |
Dextropropoxyphene (INN); Propoxypene |
(P) unclassified |
| D07810 |
Diacetylmorphine hydrochloride; Diamorphine hydrochloride; Heroin hydrochloride |
(P) unclassified |
| D07820 |
Dicycloverine (INN); Dicyclomine; Dicymine (TN) |
(P) unclassified |
| D07821 |
Dihexyverine (INN) |
(P) unclassified |
| D07830 |
Dihydralazine sulfate; Dihydralazine hydrogen sulfate; Nepresol (TN) |
(P) unclassified |
| D07831 |
Dihydrocodeine (INN); Remedacen (TN) |
(P) unclassified |
| D07832 |
Dihydrocodeine thiocyanate; Paracodin (TN) |
(P) unclassified |
| D07853 |
Dimetindene (INN); Dimethindene |
(P) unclassified |
| D07854 |
Dimetotiazine (INN); Fonazine; Migristene (TN) |
(P) Target: HTR2A HTR2C |
| D07860 |
Dioxopromethazine hydrochloride; Prothanon gel (TN) |
(P) unclassified |
| D07862 |
Diphenylpyraline (INN) |
(P) unclassified |
| D07874 |
Doxazosin (INN); Cardura XL (TN) |
(P) unclassified |
| D07878 |
Doxylamine (INN) |
(P) unclassified |
| D07890 |
Emedastine (INN); Emadine (TN) |
(P) unclassified |
| D07900 |
Epinastine (INN); Purivist (TN) |
(P) unclassified |
| D07904 |
Eptazocine (INN) |
(P) unclassified |
| D07909 |
Erythromycin thiocyanate; Erythrocin (TN) |
(P) unclassified |
| D07910 |
Erythromycin stinoprate (INN); Erysec (TN) |
(P) unclassified |
| D07928 |
Ethinylestradiol propanesulfonate; Turisteron (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D07937 |
Etorphine (INN) |
(P) unclassified |
| D07951 |
Fentonium bromide (INN); Ulcesium (TN) |
(P) unclassified |
| D07958 |
Fexofenadine (INN); Telfast (TN) |
(P) unclassified |
| D07984 |
Fluvoxamine (INN) |
(P) CYP inhibition: CYP1A2 CYP3A4 |
| D07990 |
Formoterol (INN); Oxis (TN) |
(CI) unclassified |
| D07993 |
Fosphenytoin (INN) |
(P) CYP induction: CYP3A4 |
| D08030 |
Guanethidine (INN) |
(P) unclassified |
| D08031 |
Guanfacine (INN); Estulic (TN) |
(CI,P) Enzyme: CYP3A4 / Target: ADRA2A |
| D08039 |
Hexoprenaline (INN); Ipradol (TN) |
(CI) unclassified |
| D08041 |
Homochlorcyclizine (INN) |
(P) unclassified |
| D08044 |
Hydralazine (INN); Hidral (TN) |
(P) unclassified |
| D08047 |
Hydromorphone (INN) |
(P) unclassified |
| D08054 |
Hydroxyzine (INN); Marex (TN) |
(P) unclassified |
| D08080 |
Insulin injection, biphasic isophane (BAN); Biphasic isophane insuline human (genetical recombination) injectable aqueous suspension (JP18); Insulin Humacart (TN) |
(P) CYP induction: CYP1A2 |
| D08085 |
Iproniazid phosphate; Marsilid (TN) |
(P) unclassified |
| D08090 |
Isoprenaline (INN) |
(CI) unclassified |
| D08091 |
Isothipendyl (INN); Actapront (TN) |
(P) unclassified |
| D08092 |
Isoxsuprine (INN); Dilator (TN) |
(CI) unclassified |
| D08093 |
Isoxsuprine lactate; Duphaspasmin [veterinary] (TN) |
(CI) unclassified |
| D08099 |
Ketanserin tartrate; Sufrexal (TN) |
(P) Target: HTR2A |
| D08100 |
Ketobemidone (INN) |
(P) unclassified |
| D08101 |
Ketobemidone hydrochloride; Ketogan (TN) |
(P) unclassified |
| D08105 |
Ketotifen (INN); Alaway (TN) |
(P) unclassified |
| D08117 |
Levocabastine (INN); Livostin (TN) |
(P) unclassified |
| D08118 |
Levocetirizine dihydrochloride (USP); Levocetirizine hydrochloride (JAN); Xyzal (TN) |
(P) Enzyme: CYP3A4 |
| D08121 |
Levomethadone (INN) |
(P) unclassified |
| D08122 |
Levomethadone hydrochloride; L-polamidon (TN) |
(P) unclassified |
| D08123 |
Levorphanol (INN) |
(P) unclassified |
| D08124 |
Levosalbutamol (INN); Levalbuterol |
(CI) unclassified |
| D08133 |
Lithium; Normothymin-E (TN) |
(P) unclassified |
| D08134 |
Lithium acetate; Quilonorm (TN) |
(P) unclassified |
| D08135 |
Lithium bromide |
(P) unclassified |
| D08136 |
Lithium gluconate; Lithioderm (TN) |
(P) unclassified |
| D08137 |
Lithium sulfate; Lithionit (TN) |
(P) unclassified |
| D08141 |
Lofexidine (INN) |
(CI) Target: ADRA2A ADRA2B ADRA2C |
| D08145 |
Loprazolam mesilate; Loprazolam mesylate; Loprazolam methanesulfonate; Havlane (TN) |
(P) unclassified |
| D08157 |
Mazaticol (INN) |
(P) unclassified |
| D08160 |
Mebeverine (INN); Arluy (TN) |
(P) unclassified |
| D08161 |
Mebhydrolin (INN); Bexidal (TN) |
(P) unclassified |
| D08163 |
Meclozine (BAN); Meclizine; Nevidoxine (TN) |
(P) unclassified |
| D08165 |
Medetomidine (INN); Domitor [veterinary] (TN) |
(CI) Target: ADRA2A ADRA2B ADRA2C |
| D08182 |
Meptazinol (INN) |
(P) unclassified |
| D08183 |
Mepyramine (INN) |
(P) unclassified |
| D08184 |
Mepyramine theophyllineacetate; Mepifiline; Fluidasa (TN) |
(P) unclassified |
| D08192 |
Metaraminol (INN) |
(CI) Target: ADRA2A ADRA2B ADRA2C |
| D08194 |
Deserpidine (INN); Halmonyl (TN) |
(P) unclassified |
| D08195 |
Methadone (BAN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D08201 |
Methoxamine (BAN) |
(CI) unclassified |
| D08205 |
Methyldopa (INN); Aldomet (TN) |
(CI,P) Target: ADRA2A ADRA2B ADRA2C |
| D08206 |
Methylephedrine (BAN) |
(CI) Target: ADRA2A ADRA2B ADRA2C |
| D08209 |
Metixene (INN) |
(P) unclassified |
| D08212 |
Trimazosin (INN) |
(P) unclassified |
| D08217 |
Mibefradil (INN) |
(P) CYP inhibition: CYP1A2 |
| D08220 |
Midodrine (INN) |
(CI) unclassified |
| D08233 |
Morphine (BAN); Substitol (TN) |
(P) unclassified |
| D08234 |
Morphine tartrate |
(P) unclassified |
| D08246 |
Nalbuphine (INN); Intapan (TN) |
(P) unclassified |
| D08253 |
Naphazoline (INN) |
(CI) unclassified |
| D08254 |
Endralazine (INN) |
(P) unclassified |
| D08259 |
Nelfinavir (INN); Viracept (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D08273 |
Nicomorphine hydrochloride; Vilan (TN) |
(P) unclassified |
| D08283 |
Nordazepam (INN); Calmday (TN) |
(P) Enzyme: CYP3A4 |
| D08284 |
Norepinephrine hydrochoride; (-)-Noradrenaline hydrochloride; Arterenol (TN) |
(CI) Target: ADRA2A ADRA2B ADRA2C |
| D08286 |
Norfenefrine (INN) |
(CI) unclassified |
| D08287 |
Norfloxacin nicotinate; Quinabic soluble powder (TN) [veterinary] |
(P) Enzyme: CYP1A2 / CYP inhibition: CYP1A2 |
| D08293 |
Olopatadine (INN) |
(P) unclassified |
| D08297 |
Opipramol (INN) |
(P) Target: HTR2A HTR2C |
| D08300 |
Orciprenaline (INN); Metaproterenol |
(CI) unclassified |
| D08305 |
Orphenadrine (INN); Mialgin (TN) |
(P) unclassified |
| D08308 |
Oxedrine tartrate; Dacryoboraline (TN) |
(CI) unclassified |
| D08309 |
Oxedrine hydrochloride; Ocuton (TN) |
(CI) unclassified |
| D08322 |
Oxymetazoline (INN); Operil (TN) |
(CI) unclassified |
| D08323 |
Oxymorphone (INN) |
(P) unclassified |
| D08325 |
Oxyphencyclimine (INN) |
(P) unclassified |
| D08343 |
Pethidine (INN); Meperidine |
(P) unclassified |
| D08349 |
Phenelzine (BAN) |
(P) unclassified |
| D08353 |
Phenindamine (INN) |
(P) unclassified |
| D08355 |
Pheniramine (INN) |
(P) unclassified |
| D08356 |
Phenobarbital diethylamine; Gratusminal (TN) |
(P) unclassified |
| D08365 |
Phenylephrine (INN); Phenylephrine Minims (TN) |
(CI) unclassified |
| D08366 |
Phenylephrine tartrate; L-Phenylephrine tartrate; Boraline (TN) |
(CI) unclassified |
| D08368 |
Phenylpropanolamine (INN); Fansia (TN) |
(CI,P) Target: ADRA2A ADRA2B ADRA2C / CYP inhibition: CYP1A2 |
| D08379 |
Pipemidic acid (INN); Nuril (TN) |
(P) CYP inhibition: CYP1A2 |
| D08382 |
Piperidolate (INN) |
(P) unclassified |
| D08384 |
Pipethanate (INN); Piperilate |
(P) unclassified |
| D08387 |
Pirbuterol (INN) |
(CI) unclassified |
| D08389 |
Pirenzepine (USAN/INN) |
(P) unclassified |
| D08392 |
Pirlindole (INN); Pyrazidol (TN) |
(P) unclassified |
| D08393 |
Pirlindole hydrochloride; Implementor (TN) |
(P) unclassified |
| D08395 |
Piroheptine (INN) |
(P) unclassified |
| D08411 |
Prazosin (INN); Minipress (TN) |
(P) unclassified |
| D08424 |
Procaterol (INN); Meptin (TN) |
(CI) Enzyme: CYP3A4 |
| D08425 |
Procyclidine (INN) |
(P) unclassified |
| D08426 |
Profenamine (INN) |
(P) unclassified |
| D08432 |
Promethazine maleate; Romergan (TN) |
(P) unclassified |
| D08441 |
Propiverine (INN) |
(P) Enzyme: CYP3A4 |
| D08449 |
Pseudoephedrine (INN); Neodurasina (TN); Acunaso (TN) |
(CI) Target: ADRA2A ADRA2B ADRA2C |
| D08453 |
Pargyline (INN) |
(P) unclassified |
| D08456 |
Quetiapine (INN); Norsic (TN) |
(P) Enzyme: CYP3A4 / Target: HTR2A |
| D08469 |
Rasagiline (USAN/INN); Azilect (TN) |
(P) Enzyme: CYP1A2 |
| D08473 |
Remifentanil (INN); Ultiva (TN) |
(P) unclassified |
| D08474 |
Reproterol (INN) |
(CI) unclassified |
| D08479 |
Rifampicin sodium; Rifadine (TN) |
(P) CYP induction: CYP3A4 |
| D08481 |
Rilmazafone (INN) |
(P) Enzyme: CYP3A4 |
| D08482 |
Rilmenidine (INN); Hyperium (TN) |
(P) Target: ADRA2A ADRA2B ADRA2C |
| D08487 |
Romifidine (INN); Sedivet (TN) |
(CI) Target: ADRA2A ADRA2B ADRA2C |
| D08497 |
Rupatadine fumarate (JAN/USAN); Rinialer (TN); Rupafin (TN) |
(P) Enzyme: CYP3A4 |
| D08517 |
Sitaxentan sodium (USAN); Thelin (TN) |
(P) unclassified |
| D08522 |
Solifenacin (INN) |
(P) Enzyme: CYP3A4 |
| D08570 |
Terbutaline (INN); Asthmasian (TN) |
(CI) unclassified |
| D08575 |
Tetrabenazine (JAN/INN); Nitoman (TN); Xenazine (TN) |
(P) Enzyme: CYP1A2 |
| D08578 |
Tetryzoline (INN); Tetrahydrozoline; Caltheon (TN) |
(CI) unclassified |
| D08587 |
Thonzylamine (INN); Tonamil (TN) |
(P) unclassified |
| D08594 |
Ticlopidine (INN) |
(P) CYP inhibition: CYP1A2 |
| D08595 |
Tiemonium methylsulfate; Visceralgine (TN) |
(P) unclassified |
| D08597 |
Tilidine (INN) |
(P) unclassified |
| D08611 |
Tizanidine (INN); Sirdalud (TN) |
(CI) Enzyme: CYP1A2 / Target: ADRA2A ADRA2B ADRA2C |
| D08616 |
Teneligliptin (INN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D08623 |
Tramadol (INN); Amanda (TN) |
(P) Enzyme: CYP3A4 |
| D08625 |
Tranylcypromine (INN); Parnate (TN) |
(P) unclassified |
| D08629 |
Tretoquinol (INN) |
(CI) unclassified |
| D08638 |
Trihexyphenidyl (INN); Apo-trihex (TN) |
(P) unclassified |
| D08645 |
Tripelennamine (INN) |
(P) unclassified |
| D08648 |
Triprolidine (INN) |
(P) unclassified |
| D08653 |
Tropatepine hydrochloride; Lepticur (TN) |
(P) unclassified |
| D08662 |
Urapidil hydrochloride; Ebrantil (TN) |
(P) unclassified |
| D08667 |
Calcium valproate; Valproic acid calcium salt; Convulsofin (TN) |
(P) unclassified |
| D08683 |
Xylazine (USP/INN); Chanazine (TN) |
(CI) Target: ADRA2A ADRA2B ADRA2C |
| D08768 |
Promethazine hibenzate; Hiberna (TN) |
(P) unclassified |
| D08774 |
Amoxicillin hydrate, clarithromycin and lansoprazole; Lansap (TN); Prevpac (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D08837 |
Aclidinium bromide (JAN/USAN/INN); Tudorza (TN); Eklira (TN) |
(P) CYP inhibition: CYP3A4 |
| D08838 |
Acotiamide hydrochloride (USAN); Acotiamide hydrochloride hydrate (JAN) |
(P) unclassified |
| D08850 |
Amibegron (USAN/INN) |
(CI) unclassified |
| D08851 |
Amibegron hydrochloride (USAN) |
(CI) unclassified |
| D08923 |
Fesoterodine fumarate (JAN/USAN); Toviaz (TN) |
(P) Enzyme: CYP3A4 |
| D08945 |
Milveterol hydrochloride (USAN) |
(CI) unclassified |
| D08966 |
Phenylephrine bitartrate (USP) |
(CI) unclassified |
| D09012 |
Telaprevir (JAN/USAN/INN); Incivek (TN); Incivo (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D09215 |
Eslicarbazepine (USAN/INN) |
(P) CYP induction: CYP3A4 |
| D09318 |
Indacaterol (USAN/INN) |
(CI) Enzyme: CYP3A4 |
| D09319 |
Indacaterol maleate (JAN/USAN); Arcapta (TN) |
(CI) Enzyme: CYP3A4 |
| D09344 |
Fasobegron (INN) |
(CI) unclassified |
| D09394 |
Fidaxomicin (JAN/USAN); Dificid (TN); Dificlir (TN) |
(P) CYP inhibition: CYP3A4 |
| D09402 |
Darotropium bromide (USAN/INN) |
(P) unclassified |
| D09535 |
Mirabegron (JAN/USAN/INN); Myrbetriq (TN) |
(CI) Enzyme: CYP3A4 |
| D09570 |
Bilastine (JAN/INN); Bilanoa (TN) |
(P) unclassified |
| D09572 |
Riociguat (JAN/USAN/INN); Adempas (TN) |
(P) unclassified |
| D09612 |
Eslicarbazepine acetate (USAN); Zebinix (TN); Aptiom (TN) |
(P) CYP induction: CYP3A4 |
| D09638 |
Lomitapide mesylate (USAN); Lomitapide mesilate (JAN); Juxtapid (TN); Lojuxta (TN) |
(P) Enzyme: CYP3A4 |
| D09670 |
Sotatercept (USAN/INN); Sotatercept (genetical recombination) (JAN); sotatercept-csrk; Winrevair (TN); Airwin (TN) |
(P) unclassified |
| D09696 |
Vilanterol (USAN/INN) |
(CI) unclassified |
| D09697 |
Vilanterol trifenatate (JAN/USAN) |
(CI) unclassified |
| D09705 |
Bepotastine (USAN/INN) |
(P) unclassified |
| D09731 |
Crizotinib (JAN/USAN/INN); Xalkori (TN) |
(P) Enzyme: CYP3A4 |
| D09732 |
Ritobegron ethyl hydrochloride (JAN) |
(CI) unclassified |
| D09756 |
Teneligliptin hydrobromide hydrate (JAN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D09773 |
Isoniazid glucuronate sodium (JAN) |
(P) unclassified |
| D09784 |
Garomefrine hydrochloride (JAN); Garomefrin hydrochloride; NS 49 |
(CI) unclassified |
| D09794 |
Norepinephrine hydrochloride (JAN); (+/-)-Noradrenaline hydrochloride |
(CI) Target: ADRA2A ADRA2B ADRA2C |
| D09799 |
Carotegrast methyl (JAN); Carogra (TN) |
(P) CYP inhibition: CYP3A4 |
| D09808 |
Carbinoxamine diphenyldisulfonate (JAN) |
(P) unclassified |
| D09819 |
Chlorpromazine tannate (JAN) |
(P) Target: ADRA2A ADRA2B ADRA2C HTR2A HTR2C |
| D09842 |
dl-Methylephedrine saccharinate (JAN) |
(CI) Target: ADRA2A ADRA2B ADRA2C |
| D09996 |
Vemurafenib (JAN/USAN/INN); Zelboraf (TN) |
(P) CYP inhibition: CYP1A2 / CYP induction: CYP3A4 |
| D09999 |
Tramadol hydrochloride and acetaminophen; Tramcet (TN) |
(P) Enzyme: CYP3A4 |
| D10003 |
Hemin (JAN); Normosang (TN); Panhematin (TN) |
(P) CYP induction: CYP3A4 |
| D10020 |
Olodaterol hydrochloride (JAN/USAN); Striverdi respimat (TN) |
(CI) unclassified |
| D10064 |
Dabrafenib (USAN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D10093 |
Asunaprevir (JAN/USAN); Sunvepra (TN) |
(P) CYP induction: CYP3A4 |
| D10104 |
Dabrafenib mesylate (USAN); Dabrafenib mesilate (JAN); Tafinlar (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D10135 |
Macitentan (JAN/USAN); Opsumit (TN) |
(P) Enzyme: CYP3A4 |
| D10145 |
Olodaterol (USAN/INN); Striverdi respimat (TN) |
(CI) unclassified |
| D10158 |
Safinamide (USAN/INN) |
(P) unclassified |
| D10161 |
Sarilumab (USAN); Sarilumab (genetical receombination) (JAN); Kevzara (TN) |
(P) unclassified |
| D10180 |
Umeclidinium (USAN) |
(P) unclassified |
| D10181 |
Umeclidinium bromide (JAN/USAN); Incruse ellipta (TN) |
(P) unclassified |
| D10185 |
Vortioxetine hydrobromide (JAN/USAN); Brintellix (TN); Trintellix (TN) |
(P) Target: HTR3A HTR3B HTR3C HTR3D HTR3E |
| D10191 |
Safinamide mesylate (USAN); Safinamide mesilate (JAN); Safinamide methanesulfonate; Xadago (TN); Equfina (TN) |
(P) unclassified |
| D10199 |
Tapentadol hydrochloride (JAN); Nucynta (TN) |
(P) unclassified |
| D10218 |
Enzalutamide (JAN/USAN); Xtandi (TN) |
(P) unclassified |
| D10219 |
Abediterol (USAN/INN) |
(CI) unclassified |
| D10220 |
Abediterol napadisylate (USAN) |
(CI) unclassified |
| D10246 |
Omeprazole, clarithromycin and amoxicillin; Omeclamox-pak (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D10267 |
Methyldopa and hydrochlorothiazide |
(P) unclassified |
| D10293 |
Carbidopa, levodopa and entacapone; Stalevo (TN) |
(P) unclassified |
| D10372 |
Palbociclib (JAN/USAN); Ibrance (TN) |
(P) unclassified |
| D10466 |
Vonoprazan fumarate (JAN/USAN); Takecab (TN); Voquezna (TN) |
(P) Enzyme: CYP3A4 |
| D10516 |
Aripiprazole hydrate (JAN); Aripiprazole monohydrate; Abilify maintena (TN) |
(CI) Enzyme: CYP3A4 / Target: HTR2A |
| D10519 |
Rabeprazole, amoxicillin and clarithromycin; Rabecure (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D10533 |
Umeclidinium bromide and vilanterol; Anoro (TN) |
(CI) Enzyme: CYP3A4 |
| D10537 |
Methylthioninium chloride hydrate (JAN); Methylene blue (TN) |
(P) CYP inhibition: CYP1A2 |
| D10551 |
Ceritinib (JAN/USAN/INN); Zykadia (TN) |
(P) unclassified |
| D10564 |
Amenamevir (JAN/INN); Amenalief (TN) |
(P) unclassified |
| D10566 |
Pasireotide pamoate (JAN); Signifor lar (TN) |
(P) unclassified |
| D10582 |
Dasabuvir, ombitasvir, paritaprevir and ritonavir; Viekira pak (TN) |
(P) CYP inhibition: CYP3A4 |
| D10591 |
Clonidine and chlorthalidone; Clorpres (TN) |
(P) unclassified |
| D10643 |
Isavuconazonium sulfate (JAN/USAN); Cresemba (TN) |
(P) unclassified |
| D10689 |
Amifampridine phosphate (JAN/USAN); Firdapse (TN) |
(P) unclassified |
| D10745 |
Ombitasvir, paritaprevir and ritonavir; Technivie (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D10762 |
Fosravuconazole L-lysine ethanolate (JAN) |
(P) unclassified |
| D10774 |
Vonoprazan, amoxicillin and metronidazole; Vonopion (TN) |
(P) Enzyme: CYP3A4 |
| D10775 |
Vonoprazan, amoxicillin and clarithromycin; Vonosap (TN); Voquenza (TN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D10793 |
Sodium picosulfate hydrate, magnesium oxide and citric acid, anhydrous; Picoprep (TN); Prepopik (TN); Clenpiq (TN) |
(P) unclassified |
| D10801 |
Letermovir (JAN/USAN/INN); Prevymis (TN) |
(P) unclassified |
| D10811 |
Fentanyl hydrochloride (JAN); Ionsys (TN) |
(P) Enzyme: CYP3A4 |
| D10822 |
Ciprofloxacin hydrate (JAN); Ciprofloxacin hemiheptahydrate |
(P) CYP inhibition: CYP1A2 |
| D10829 |
Rasagiline tartrate; Rasagiline (TN) |
(P) Enzyme: CYP1A2 |
| D10882 |
Daclatasvir, asunaprevir and beclabuvir; Ximency (TN) |
(P) CYP induction: CYP3A4 |
| D10891 |
Capmatinib hydrochloride (USAN); Capmatinib hydrochloride hydrate (JAN); Tabrecta (TN) |
(P) Enzyme: CYP3A4 |
| D10895 |
Fosaprepitant (INN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 / CYP induction: CYP3A4 |
| D10926 |
Entrectinib (JAN/USAN/INN); Rozlytrek (TN) |
(P) Enzyme: CYP3A4 |
| D10938 |
Glycopyrronium (USAN) |
(P) unclassified |
| D10939 |
Glycopyrronium tosylate (USAN); Glycopyrronium tosilate hydrate (JAN); Glycopyrronium tosylate monohydrate; Qbrexza (TN); Rapifort (TN) |
(P) unclassified |
| D10989 |
Sofpironium bromide (JAN/USAN/INN); Ecclock (TN); Sofdra (TN) |
(P) Enzyme: CYP3A4 |
| D10990 |
Somatrogon (USAN/INN); Somatrogon (genetical recombination) (JAN); Somatrogon-ghla; Ngenla (TN) |
(P) unclassified |
| D11009 |
Indacaterol acetate (JAN) |
(CI) Enzyme: CYP3A4 |
| D11012 |
Lorlatinib (JAN/USAN/INN); Lorbrena (TN) |
(P) unclassified |
| D11027 |
Ropeginterferon alfa-2b (INN); Ropeginterferon alfa-2b (genetical recombination) (JAN); Ropeginterferon alfa-2b-njft; Besremi (TN) |
(P) unclassified |
| D11040 |
Apalutamide (JAN/INN); Erleada (TN) |
(P) Enzyme: CYP3A4 / CYP induction: CYP3A4 |
| D11053 |
Encorafenib (JAN/USAN/INN); Braftovi (TN) |
(P) Enzyme: CYP3A4 |
| D11062 |
Osilodrostat phosphate (JAN/USAN); Isturisa (TN) |
(P) Enzyme: CYP3A4 |
| D11090 |
Ivosidenib (JAN/USAN/INN); Tibsovo (TN) |
(P) unclassified |
| D11138 |
Larotrectinib sulfate (JAN/USAN); Vitrakvi (TN) |
(P) unclassified |
| D11194 |
Somapacitan (USAN/INN); Somapacitan (genetical recombination) (JAN); Somapacitan-beco; Sogroya (TN) |
(P) unclassified |
| D11208 |
Elafibranor (USAN); Iqirvo (TN) |
(P) CYP induction: CYP3A4 |
| D11214 |
Oliceridine (USAN/INN); Olinvyk (TN) |
(P) unclassified |
| D11290 |
Articaine hydrochloride and epinephrine; Articaine hydrochloride and adrenaline; Orabloc (TN); Septocaine (TN); Ultacan (TN) |
(P) unclassified |
| D11296 |
Fedratinib hydrochloride (USAN); Fedratinib hydrochloride hydrate (JAN); Fedratinib dihydrochloride monohydrate; Inrebic (TN) |
(P) Enzyme: CYP3A4 |
| D11370 |
Fosnetupitant chloride hydrochloride (JAN/USAN); Arokaris (TN) |
(P) unclassified |
| D11371 |
Capivasertib (JAN/USAN); Truqap (TN) |
(P) Enzyme: CYP3A4 |
| D11422 |
Zanubrutinib (JAN/USAN/INN); Brukinsa (TN) |
(P) unclassified |
| D11441 |
Aprocitentan (USAN/INN); Tryvio (TN) |
(P) unclassified |
| D11454 |
Repotrectinib (JAN/USAN); Augtyro (TN) |
(P) Enzyme: CYP3A4 |
| D11485 |
Tazemetostat hydrobromide (JAN/USAN); Tazverik (TN) |
(P) unclassified |
| D11557 |
Tecovirimat hydrate (JAN); Tecovirimat monohydrate; Tpoxx (TN); Tepoxx (TN) |
(P) unclassified |
| D11673 |
Berotralstat (USAN/INN) |
(P) CYP inhibition: CYP3A4 |
| D11674 |
Berotralstat hydrochloride (JAN/USAN); Orladeyo (TN) |
(P) CYP inhibition: CYP3A4 |
| D11708 |
Givosiran sodium (JAN); Givlaari (TN) |
(P) unclassified |
| D11713 |
Selpercatinib (JAN/USAN/INN); Retevmo (TN) |
(P) Enzyme: CYP3A4 |
| D11804 |
Aspirin and vonoprazan; Cabpirin (TN) |
(P) unclassified |
| D11816 |
Belumosudil mesylate (USAN); Belumosudil mesilate (JAN); Rezurock (TN) |
(P) unclassified |
| D11887 |
Daridorexant hydrochloride (JAN/USAN); Quviviq (TN) |
(P) unclassified |
| D11920 |
Pimitespib (JAN); Jeselhy (TN) |
(P) unclassified |
| D11954 |
Belzutifan (JAN/USAN/INN); Welireg (TN) |
(P) unclassified |
| D11968 |
Teneligliptin hydrobromide (JAN) |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D11970 |
Ritlecitinib tosylate (USAN); Ritlecitinib tosilate (JAN); Litfulo (TN) |
(P) CYP inhibition: CYP1A2 |
| D12050 |
Pirtobrutinib (JAN/USAN); Jaypirca (TN) |
(P) Enzyme: CYP3A4 |
| D12055 |
Sotorasib (JAN/USAN); Lumakras (TN) |
(P) unclassified |
| D12245 |
Lazertinib mesylate (USAN); Lazertinib mesilate hydrate (JAN); Lazcluze (TN) |
(P) Enzyme: CYP3A4 |
| D12252 |
Iptacopan hydrochloride (USAN); Iptacopan hydrochloride hydrate (JAN); Iptacopan hydrochloride monohydrate; Fabhalta (TN) |
(P) unclassified |
| D12353 |
Ensitrelvir fumarate (USAN); Ensitrelvir fumaric acid (JAN); Xocova (TN) |
(P) unclassified |
| D12444 |
Nilotinib hydrochloride dihydrate (JAN) |
(P) Enzyme: CYP3A4 |
| D12494 |
Foslevodopa and foscarbidopa; Vyalev (TN) |
(P) unclassified |
| D12586 |
Mifepristone and misoprostol; Mefeego (TN) |
(P) unclassified |
| D12637 |
Darunavir hydrate |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D12660 |
Alphacetylmethadol (INN) |
(P) unclassified |
| D12661 |
Betacetylmethadol (INN) |
(P) unclassified |
| D12662 |
Allylprodine (INN) |
(P) unclassified |
| D12663 |
Ethylmethylthiambutene (INN) |
(P) unclassified |
| D12664 |
Diethylthiambutene (INN) |
(P) unclassified |
| D12665 |
Dimethylthiambutene (INN) |
(P) unclassified |
| D12666 |
Alphameprodine (INN); alpha-Meprodine |
(P) unclassified |
| D12667 |
Betameprodine (INN); beta-Meprodine |
(P) unclassified |
| D12668 |
Clonitazene (INN) |
(P) unclassified |
| D12669 |
Etonitazene (INN) |
(P) unclassified |
| D12670 |
Desomorphine (INN) |
(P) unclassified |
| D12671 |
Dipipanone (BAN) |
(P) unclassified |
| D12672 |
Dimenoxadol (INN) |
(P) unclassified |
| D12673 |
Dimepheptanol (INN) |
(P) unclassified |
| D12674 |
Alphamethadol (INN) |
(P) unclassified |
| D12675 |
Betamethadol (INN) |
(P) unclassified |
| D12676 |
Isomethadone (INN) |
(P) unclassified |
| D12677 |
Proheptazine (INN) |
(P) unclassified |
| D12678 |
Alphaprodine (INN) |
(P) unclassified |
| D12679 |
Betaprodine (INN) |
(P) unclassified |
| D12680 |
Etoxeridine (INN) |
(P) unclassified |
| D12681 |
Hydroxypethidine (INN); Bemidone |
(P) unclassified |
| D12682 |
Furethidine (INN) |
(P) unclassified |
| D12683 |
Piminodine (INN) |
(P) unclassified |
| D12685 |
Benzethidine (INN) |
(P) unclassified |
| D12686 |
Hydromorphinol (INN) |
(P) unclassified |
| D12687 |
Levophenacylmorphan (INN) |
(P) unclassified |
| D12688 |
Phenomorphan (INN) |
(P) unclassified |
| D12689 |
Methyldihydromorphine (INN) |
(P) unclassified |
| D12690 |
Metopon (BAN); Methyldihydromorphinone |
(P) unclassified |
| D12691 |
Methyldesorphine (INN) |
(P) unclassified |
| D12692 |
Norlevorphanol (INN) |
(P) unclassified |
| D12693 |
Phenampromide (INN) |
(P) unclassified |
| D12694 |
Diampromide (INN) |
(P) unclassified |
| D12695 |
Levomoramide (INN) |
(P) unclassified |
| D12696 |
Levomethorphan (INN) |
(P) unclassified |
| D12697 |
Morpheridin (INN) |
(P) unclassified |
| D12698 |
Phenadoxone (INN) |
(P) unclassified |
| D12699 |
Dioxaphetyl butyrate (INN) |
(P) unclassified |
| D12700 |
Acetorphine (INN) |
(P) unclassified |
| D12701 |
Norpipanone (INN) |
(P) unclassified |
| D12752 |
Darunavir propylene glycolate |
(P) Enzyme: CYP3A4 / CYP inhibition: CYP3A4 |
| D12934 |
Dibutepinephrine (USAN/INN) |
(CI) Target: ADRA2A ADRA2B ADRA2C |
| D12935 |
Dibutepinephrine hydrochloride (USAN) |
(CI) Target: ADRA2A ADRA2B ADRA2C |
| D12963 |
Macitentan and tadalafil; Opsynvi (TN); Yuvanci (TN) |
(P) unclassified |
| D13025 |
Properidine (INN); Ipropethidine |
(P) unclassified |
