Entry |
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Symbol |
RRP46, EXOSC5
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Name |
exosome complex component RRP46
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Pathway |
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Disease |
H02549 | Cerebellar ataxia, brain abnormalities, and cardiac conduction defects |
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Brite |
KEGG Orthology (KO) [BR:ko00001]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
03018 RNA degradation
K12590 RRP46, EXOSC5; exosome complex component RRP46
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03019 Messenger RNA biogenesis
K12590 RRP46, EXOSC5; exosome complex component RRP46
Messenger RNA biogenesis [BR:ko03019]
Eukaryotic type
mRNA degradation factors
3'-5' decay
Core exosome factors
K12590 RRP46, EXOSC5; exosome complex component RRP46
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Other DBs |
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Genes |
» show all
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Reference |
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Authors |
Wang HW, Wang J, Ding F, Callahan K, Bratkowski MA, Butler JS, Nogales E, Ke A |
Title |
Architecture of the yeast Rrp44 exosome complex suggests routes of RNA recruitment for 3' end processing. |
Journal |
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Sequence |
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Reference |
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Authors |
Allmang C, Petfalski E, Podtelejnikov A, Mann M, Tollervey D, Mitchell P |
Title |
The yeast exosome and human PM-Scl are related complexes of 3' - 5' exonucleases. |
Journal |
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Sequence |
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Reference |
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Authors |
Mukherjee D, Gao M, O'Connor JP, Raijmakers R, Pruijn G, Lutz CS, Wilusz J |
Title |
The mammalian exosome mediates the efficient degradation of mRNAs that contain AU-rich elements. |
Journal |
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Sequence |
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LinkDB |
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