KEGG   ORTHOLOGY: K14966Help
Entry
K14966                      KO                                     

Name
HCFC
Definition
host cell factor
Pathway
ko04212  Longevity regulating pathway - worm
ko05168  Herpes simplex virus 1 infection
Disease
H00480  X-linked mental retardation
H02222  Methylmalonic acidemia and homocysteinemia, cblX type
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09149 Aging
   04212 Longevity regulating pathway - worm
    K14966  HCFC; host cell factor
 09160 Human Diseases
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    K14966  HCFC; host cell factor
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins
    K14966  HCFC; host cell factor
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins
    K14966  HCFC; host cell factor
   03029 Mitochondrial biogenesis
    K14966  HCFC; host cell factor
Protein phosphatases and associated proteins [BR:ko01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     K14966  HCFC; host cell factor
Chromosome and associated proteins [BR:ko03036]
 Eukaryotic type
  Histone modification proteins
   HAT complexes
    NSL complex
     K14966  HCFC; host cell factor
   HMT complexes
    COMPASS/SET1 complex
     K14966  HCFC; host cell factor
    MLL-HCF complex
     K14966  HCFC; host cell factor
Mitochondrial biogenesis [BR:ko03029]
 Mitochondrial quality control factors
  Regulator of mitochondrial biogenesis
   Other regulator of mitochondrial biogenesis
    K14966  HCFC; host cell factor
BRITE hierarchy
Genes
HSA: 29915(HCFC2) 3054(HCFC1)
PTR: 452190(HCFC2) 465933(HCFC1)
PPS: 100968960(HCFC1) 100978797(HCFC2)
GGO: 101130172(HCFC1) 101132001(HCFC2)
PON: 100436774(HCFC1) 100453490(HCFC2)
NLE: 100579274(HCFC2) 100587818(HCFC1)
MCC: 106995371(HCFC1) 700316(HCFC2)
MCF: 101866531(HCFC1) 102140886(HCFC2)
CSAB: 103232813(HCFC1) 103238981(HCFC2)
RRO: 104657472(HCFC2) 104661167(HCFC1)
RBB: 108535066(HCFC1) 108544246(HCFC2)
CJC: 100399829(HCFC2) 100413551(HCFC1)
SBQ: 101036199(HCFC1) 101040133(HCFC2)
MMU: 15161(Hcfc1) 67933(Hcfc2)
MCAL: 110286238(Hcfc1) 110303711(Hcfc2)
MPAH: 110313981(Hcfc1) 110326139(Hcfc2)
RNO: 100911260 314704(Hcfc2) 363519(Hcfc1)
MUN: 110542609(Hcfc1) 110550775(Hcfc2)
CGE: 100774489(Hcfc1) 100774776(Hcfc2)
NGI: 103731210(Hcfc1) 103742141(Hcfc2)
HGL: 101697902(Hcfc1) 101701605(Hcfc2)
CCAN: 109675858(Hcfc2) 109701932(Hcfc1)
OCU: 100343128(HCFC2) 100352051(HCFC1)
TUP: 102473959(HCFC1) 102498540(HCFC2)
CFA: 475449(HCFC2) 492246(HCFC1)
VVP: 112911506(HCFC1) 112930660(HCFC2)
AML: 100475049(HCFC2) 100482290(HCFC1)
UMR: 103676484(HCFC2) 103679691(HCFC1)
UAH: 113247827(HCFC1) 113256063(HCFC2)
ORO: 101381881(HCFC1) 101383636(HCFC2)
FCA: 101084553(HCFC2) 101089996(HCFC1)
PTG: 102958711(HCFC2)
PPAD: 109259832(HCFC1) 109265435(HCFC2)
AJU: 106971913(HCFC2) 106989716(HCFC1)
BTA: 505341(HCFC2) 512908(HCFC1)
BOM: 102267518(HCFC2) 102277262(HCFC1)
BIU: 109555156(HCFC1) 109559459(HCFC2)
BBUB: 102400526(HCFC2) 102406843(HCFC1)
CHX: 102177156 102181658(HCFC2) 106503929(HCFC1)
OAS: 101102055(HCFC2) 101121918(HCFC1)
SSC: 100514768(HCFC2) 100523834(HCFC1)
CFR: 102504185(HCFC1) 102518490(HCFC2)
CDK: 105097479(HCFC2) 105098726(HCFC1)
BACU: 102998091(HCFC1) 103012055(HCFC2)
LVE: 103073781(HCFC1) 103082401(HCFC2)
OOR: 101282458(HCFC1) 101289068(HCFC2)
DLE: 111170585(HCFC1) 111187908(HCFC2)
PCAD: 102978215(HCFC1) 102989036(HCFC2)
ECB: 100058080(HCFC1) 100067735(HCFC2)
EPZ: 103545146 103562008(HCFC2)
EAI: 106825608(HCFC1) 106846822(HCFC2)
MYB: 102252557(HCFC2) 102258702(HCFC1)
MYD: 102766265(HCFC1) 102775162(HCFC2)
MNA: 107538793(HCFC1) 107545146(HCFC2)
HAI: 109387784(HCFC2) 109394336(HCFC1)
DRO: 112296272(HCFC1) 112321997(HCFC2)
PALE: 102888175(HCFC2) 102888833(HCFC1)
RAY: 107501159(HCFC2) 107517747(HCFC1)
MJV: 108395213(HCFC2) 108409034(HCFC1)
LAV: 100668302(HCFC1) 100671719(HCFC2)
MDO: 100021894(HCFC2)
SHR: 100920915(HCFC2) 100923376(HCFC1)
PCW: 110201514(HCFC1) 110205667(HCFC2)
OAA: 100076335(HCFC2) 100077937(HCFC1)
GGA: 418083(HCFC2)
CJO: 107314730(HCFC2) 107315782
NMEL: 110393809(HCFC2)
APLA: 101801477(HCFC2)
ACYG: 106035873(HCFC2)
TGU: 100225405(HCFC2) 115491934(HCFC1) 115491987
LSR: 110473576(HCFC2) 110481607(HCFC1)
SCAN: 103813183(HCFC2)
GFR: 102035089(HCFC2)
FAB: 101814518(HCFC2)
PHI: 102111184(HCFC1) 102111652(HCFC2)
PMAJ: 107204443(HCFC2)
CCAE: 111935980(HCFC2)
CCW: 104696238(HCFC2)
ETL: 114060730(HCFC2)
FPG: 101923529(HCFC2)
FCH: 102046299(HCFC2)
CLV: 102083684(HCFC2)
EGZ: 104132729(HCFC2)
NNI: 104013352(HCFC2)
ACUN: 113490439(HCFC2)
PADL: 103924433(HCFC2)
AAM: 106488261(HCFC2) 106493512
ASN: 102368359(HCFC2) 102375077
AMJ: 102564528(HCFC2) 102575549(HCFC1) 109282705
PSS: 102450539(HCFC2)
CMY: 102935054 102942253(HCFC2)
CPIC: 101937023(HCFC1) 101944095(HCFC2)
ACS: 100563537(hcfc2) 100563779(hcfc1)
PVT: 110078677(HCFC1) 110084779(HCFC2)
PBI: 103059522(HCFC2) 103067504(HCFC1)
PMUR: 107284221(HCFC1) 107294622(HCFC2)
TSR: 106543642(HCFC1) 106557040(HCFC2)
PMUA: 114587585(HCFC1) 114605767(HCFC2)
GJA: 107108393 107119918(HCFC2)
XLA: 108704501 108711028 494675(hcfc1.S)
XTR: 100127587(hcfc2) 100485535(hcfc1)
NPR: 108789003(HCFC2) 108790459(HCFC1)
DRE: 550401(hcfc2) 564853(hcfc1a) 565206(hcfc1b)
IPU: 108265652(hcfc1) 108279775(hcfc2)
PHYP: 113531988(hcfc2) 113534965(hcfc1)
AMEX: 103044501(hcfc1) 103047617(hcfc2)
EEE: 113572359 113575846(hcfc1) 113584413(hcfc2)
LCO: 104930603(hcfc2) 104935477 104939450(hcfc1)
NCC: 104945730(hcfc1) 104946235(hcfc2)
OLA: 101157935(hcfc1) 101161597(hcfc2)
XMA: 102220785(hcfc1) 102227032(hcfc2) 102230815
XCO: 114135097(hcfc1) 114140229 114161038(hcfc2)
PRET: 103459686(hcfc2) 103460245(hcfc1) 103465550
CVG: 107096235(hcfc2) 107099712 107100225(hcfc1)
NFU: 107381907(hcfc2) 107385861(hcfc1)
KMR: 108244400(hcfc1) 108249289(hcfc2)
ALIM: 106530523(hcfc2) 106531380(hcfc1)
CSEM: 103383033(hcfc2) 103384375(hcfc1) 103386409
MALB: 109956034(hcfc1) 109961008(hcfc2)
ELS: 105007492(hcfc2) 105017367 105028333(hcfc1)
LCM: 102351872(HCFC2) 102359967(HCFC1)
CMK: 103176800 103179826(hcfc2)
CIN: 100178580
SPU: 586153
APLC: 110983255
SKO: 102805020
DME: Dmel_CG1710(Hcf)
DER: 6555815
DSI: Dsimw501_GD24404(Dsim_GD24404)
DSR: 110185426
DPE: 6601995
DMN: 108164444
DWI: 6651638
DAZ: 108617955
DNV: 108655361
DHE: 111593702
MDE: 101889906
AAG: 5571204
AME: 551801
BIM: 100745878
BTER: 100650355
CCAL: 108627468
OBB: 114870914
SOC: 105204652
MPHA: 105831771
AEC: 105145239
ACEP: 105617068
PBAR: 105425730
VEM: 105559785
HST: 105181009
DQU: 106742762
CFO: 105256906
LHU: 105671701
PGC: 109852962
OBO: 105283850
PCF: 106787076
NVI: 100122420
CSOL: 105359359
MDL: 103569438
TCA: 657767
DPA: 109537945
ATD: 109608333
NVL: 108557160
BMOR: 101746972
BMAN: 114247014
PRAP: 111002994
HAW: 110380395
TNL: 113499867
DNX: 107170117
AGS: 114126957
RMD: 113550348
BTAB: 109030095
CLEC: 106670704
ZNE: 110831120
PVM: 113829621
TUT: 107370186
CSCU: 111638513
PTEP: 107438051
CEL: CELE_C46A5.9(hcf-1)
CBR: CBG17668(Cbr-hcf-1)
BMY: Bm1_07550
TSP: Tsp_06154
PCAN: 112572279
CRG: 105337992
MYI: 110443354
OBI: 106873592
LAK: 106180476
EGL: EGR_01412
EPA: 110247606
ADF: 107355158
AMIL: 114969348
PDAM: 113670683
SPIS: 111338427
DGT: 114530126
HMG: 100204514
AQU: 100639344
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Yokoyama A, Wang Z, Wysocka J, Sanyal M, Aufiero DJ, Kitabayashi I, Herr W, Cleary ML
  Title
Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression.
  Journal
Mol Cell Biol 24:5639-49 (2004)
DOI:10.1128/MCB.24.13.5639-5649.2004
  Sequence
[hsa:3054 29915]
Reference
  Authors
Wysocka J, Myers MP, Laherty CD, Eisenman RN, Herr W
  Title
Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell-proliferation factor HCF-1.
  Journal
Genes Dev 17:896-911 (2003)
DOI:10.1101/gad.252103
  Sequence
[hsa:3054]
Reference
  Authors
Johnson KM, Mahajan SS, Wilson AC
  Title
Herpes simplex virus transactivator VP16 discriminates between HCF-1 and a novel family member, HCF-2.
  Journal
J Virol 73:3930-40 (1999)
DOI:10.1128/JVI.73.5.3930-3940.1999
  Sequence
[hsa:29915]
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