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KO |
 09100 Metabolism
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 09120 Genetic Information Processing
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09121 Transcription
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09122 Translation
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09123 Folding, sorting and degradation
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09124 Replication and repair
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03030 DNA replication [PATH:pale03030]
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03410 Base excision repair [PATH:pale03410]
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03420 Nucleotide excision repair [PATH:pale03420]
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03430 Mismatch repair [PATH:pale03430]
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03440 Homologous recombination [PATH:pale03440]
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03450 Non-homologous end-joining [PATH:pale03450]
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03460 Fanconi anemia pathway [PATH:pale03460]
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 102888318 ATRIP; ATR-interacting protein
102889339 ATR; LOW QUALITY PROTEIN: serine/threonine-protein kinase ATR
102886782 FANCM; Fanconi anemia group M protein
102891915 FAAP24; Fanconi anemia core complex-associated protein 24
102886828 CENPS; centromere protein S
107195713 CENPX; centromere protein X
102879418 TELO2; telomere length regulation protein TEL2 homolog isoform X1
102890128 HES1; transcription factor HES-1
102890885 FAAP100; Fanconi anemia core complex-associated protein 100
102884278 FANCA; Fanconi anemia group A protein isoform X2
102891129 FANCB; Fanconi anemia group B protein
102881661 FANCC; Fanconi anemia group C protein isoform X5
102898238 FANCE; Fanconi anemia group E protein isoform X1
102892576 FANCF; Fanconi anemia group F protein
102890585 FANCG; Fanconi anemia group G protein
102884487 FANCL; E3 ubiquitin-protein ligase FANCL
102895486 WDR48; WD repeat-containing protein 48
102898461 USP1; ubiquitin carboxyl-terminal hydrolase 1 isoform X1
102879480 UBE2T; ubiquitin-conjugating enzyme E2 T isoform X2
102882939 FANCI; Fanconi anemia group I protein isoform X2
102887690 FANCD2; Fanconi anemia group D2 protein isoform X1
102896802 BRCA2; breast cancer type 2 susceptibility protein
102895844 PALB2; partner and localizer of BRCA2 isoform X1
102885802 RAD51C; DNA repair protein RAD51 homolog 3 isoform X3
102894016 RAD51; DNA repair protein RAD51 homolog 1
102895982 BRCA1; breast cancer type 1 susceptibility protein isoform X1
102890464 BRIP1; Fanconi anemia group J protein
102890629 FAN1; fanconi-associated nuclease 1
112475776 fanconi-associated nuclease 1-like isoform X1
102898392 MLH1; DNA mismatch repair protein Mlh1 isoform X1
102879718 PMS2; mismatch repair endonuclease PMS2 isoform X1
102890504 REV1; DNA repair protein REV1 isoform X5
102896156 REV3L; DNA polymerase zeta catalytic subunit isoform X2
102891912 POLH; DNA polymerase eta isoform X1
102894090 POLI; DNA polymerase iota
102890888 POLK; DNA polymerase kappa isoform X1
102898460 POLN; DNA polymerase nu
102883483 RMI1; recQ-mediated genome instability protein 1
102880328 TOP3B; DNA topoisomerase 3-beta-1 isoform X2
102878631 TOP3A; DNA topoisomerase 3-alpha isoform X1
102888215 BLM; Bloom syndrome protein isoform X1
102889870 RPA1; replication protein A 70 kDa DNA-binding subunit
102883783 RPA2; replication protein A 32 kDa subunit
102884493 RPA3; replication protein A 14 kDa subunit isoform X1
102878725 RPA4; LOW QUALITY PROTEIN: replication protein A 30 kDa subunit
102885920 MUS81; crossover junction endonuclease MUS81 isoform X7
102887468 EME1; crossover junction endonuclease EME1 isoform X1
102878659 EME2; probable crossover junction endonuclease EME2 isoform X1
102881542 ERCC4; LOW QUALITY PROTEIN: DNA repair endonuclease XPF
102891932 ERCC1; DNA excision repair protein ERCC-1 isoform X2
102889663 SLX1A; structure-specific endonuclease subunit SLX1 isoform X1
102887590 SLX4; LOW QUALITY PROTEIN: structure-specific endonuclease subunit SLX4
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K10905 ATRIP; ATR interacting protein
K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
K10896 FANCM; fanconi anemia group M protein
K10898 FAAP24; fanconi anemia-associated protein
K11511 APITD1; centromere protein S
K15360 STRA13; centromere protein X
K11137 TELO2; telomere length regulation protein
K06054 HES1; hairy and enhancer of split 1
K10993 FAAP100; fanconi anemia core complex 100 kDa subunit
K10888 FANCA; fanconi anemia group A protein
K10889 FANCB; fanconi anemia group B protein
K10890 FANCC; fanconi anemia group C protein
K10892 FANCE; fanconi anemia group E protein
K10893 FANCF; fanconi anemia group F protein
K10894 FANCG; fanconi anemia group G protein
K10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]
K15361 WDR48; WD repeat-containing protein 48
K11832 USP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]
K13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23]
K10895 FANCI; fanconi anemia group I protein
K10891 FANCD2; fanconi anemia group D2 protein
K08775 BRCA2; breast cancer 2 susceptibility protein
K10897 PALB2; partner and localizer of BRCA2
K10870 RAD51L2; RAD51-like protein 2
K04482 RAD51; DNA repair protein RAD51
K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
K15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]
K15363 FAN1; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1]
K15363 FAN1; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1]
K08734 MLH1; DNA mismatch repair protein MLH1
K10858 PMS2; DNA mismatch repair protein PMS2
K03515 REV1; DNA repair protein REV1 [EC:2.7.7.-]
K02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]
K03509 POLH; DNA polymerase eta [EC:2.7.7.7]
K03510 POLI; DNA polymerase iota [EC:2.7.7.7]
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K16618 POLN; DNA polymerase nu [EC:2.7.7.7]
K10990 RMI1; RecQ-mediated genome instability protein 1
K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
K07466 RFA1; replication factor A1
K10739 RFA2; replication factor A2
K10740 RPA3; replication factor A3
K10741 RPA4; replication factor A4
K08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-]
K10882 EME1; crossover junction endonuclease EME1 [EC:3.1.22.-]
K10883 EME2; crossover junction endonuclease EME2
K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
K10849 ERCC1; DNA excision repair protein ERCC-1
K15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]
K10484 BTBD12; structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
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09126 Chromosome
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09125 Information processing in viruses
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09130 Environmental Information Processing
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09140 Cellular Processes
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09150 Organismal Systems
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09160 Human Diseases
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09161 Cancer: overview
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05200 Pathways in cancer [PATH:pale05200]
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102886027 DCC; netrin receptor DCC
102897289 CASP3; caspase-3
102878565 CASP9; caspase-9
102887604 APPL1; DCC-interacting protein 13-alpha
102886394 CDH1; cadherin-1 isoform X1
102880017 CTNNB1; LOW QUALITY PROTEIN: catenin beta-1
102893948 CTNNA2; catenin alpha-2 isoform X3
102881133 CTNNA3; catenin alpha-3
102891804 CTNNA1; catenin alpha-1
102878657 AXIN1; axin-1 isoform X1
102885831 AXIN2; axin-2
102880260 APC; adenomatous polyposis coli protein isoform X3
102891886 APC2; adenomatous polyposis coli protein 2
102882441 GSK3B; glycogen synthase kinase-3 beta isoform X4
102885788 TCF7; transcription factor 7 isoform X4
102886093 TCF7L1; transcription factor 7-like 1
102880370 TCF7L2; transcription factor 7-like 2 isoform X2
102886933 LEF1; lymphoid enhancer-binding factor 1 isoform X1
102888083 BIRC5; baculoviral IAP repeat-containing protein 5
102895524 MYC; myc proto-oncogene protein
102885330 CCND1; G1/S-specific cyclin-D1
102888016 WNT1; proto-oncogene Wnt-1
102880959 WNT2B; protein Wnt-2b isoform X1
102885080 WNT2; protein Wnt-2
102895795 WNT3A; protein Wnt-3a
102877979 WNT3; proto-oncogene Wnt-3
102888866 WNT4; protein Wnt-4
102890342 WNT5A; protein Wnt-5a isoform X5
102881682 WNT5B; protein Wnt-5b isoform X2
102882368 WNT6; protein Wnt-6 isoform X1
102888597 WNT7A; protein Wnt-7a
102898026 WNT7B; protein Wnt-7b isoform X1
102896480 WNT8A; protein Wnt-8a
102878209 WNT8B; protein Wnt-8b
102885223 protein Wnt-9b
102884543 WNT9A; protein Wnt-9a
102882121 WNT10A; protein Wnt-10a
102888263 WNT10B; protein Wnt-10b
102877879 WNT11; protein Wnt-11
102882050 WNT16; LOW QUALITY PROTEIN: protein Wnt-16
102880538 FZD7; frizzled-7
102895634 FZD1; frizzled-1
102884150 FZD2; frizzled-2
102890038 FZD3; frizzled-3 isoform X1
102892989 FZD4; LOW QUALITY PROTEIN: frizzled-4
102877864 FZD8; LOW QUALITY PROTEIN: frizzled-8
102883426 FZD5; LOW QUALITY PROTEIN: frizzled-5
102890002 FZD6; frizzled-6
102894135 FZD10; frizzled-10
102878169 FZD9; frizzled-9
102894479 LRP5; low-density lipoprotein receptor-related protein 5
102878233 LRP6; low-density lipoprotein receptor-related protein 6
102895469 DVL3; segment polarity protein dishevelled homolog DVL-3 isoform X1
102880039 DVL2; segment polarity protein dishevelled homolog DVL-2 isoform X1
102881158 DVL1; segment polarity protein dishevelled homolog DVL-1 isoform X1
102896339 LOW QUALITY PROTEIN: proto-oncogene FRAT1
102877724 F2; prothrombin isoform X2
102892951 AGT; angiotensinogen
102886001 F2R; proteinase-activated receptor 1
102891888 F2RL3; proteinase-activated receptor 4
102891503 LPAR1; lysophosphatidic acid receptor 1 isoform X1
102891807 LPAR2; lysophosphatidic acid receptor 2
102880785 LPAR3; lysophosphatidic acid receptor 3
102881134 LPAR4; lysophosphatidic acid receptor 4
102892521 LPAR5; lysophosphatidic acid receptor 5
102892775 LPAR6; lysophosphatidic acid receptor 6
102895602 AGTR1; type-1 angiotensin II receptor
102891706 GNA12; guanine nucleotide-binding protein subunit alpha-12
102891607 GNA13; guanine nucleotide-binding protein subunit alpha-13
102879072 ARHGEF12; rho guanine nucleotide exchange factor 12
102892639 ARHGEF11; rho guanine nucleotide exchange factor 11
102894194 ARHGEF1; rho guanine nucleotide exchange factor 1 isoform X1
102892928 PLEKHG5; pleckstrin homology domain-containing family G member 5 isoform X1
102891515 RHOA; transforming protein RhoA
102879861 ROCK1; rho-associated protein kinase 1 isoform X1
102897424 ROCK2; rho-associated protein kinase 2
102881363 CXCL12; stromal cell-derived factor 1 isoform X1
102888277 CXCR4; C-X-C chemokine receptor type 4
102892785 GNAI3; guanine nucleotide-binding protein G(k) subunit alpha
102885642 GNAI1; guanine nucleotide-binding protein G(i) subunit alpha-1
102898665 GNAI2; guanine nucleotide-binding protein G(i) subunit alpha-2
102894012 PTGER1; prostaglandin E2 receptor EP1 subtype
102884861 PTGER2; prostaglandin E2 receptor EP2 subtype
102890353 PTGER3; prostaglandin E2 receptor EP3 subtype isoform X1
102886026 PTGER4; prostaglandin E2 receptor EP4 subtype
102889764 guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas
102884106 neuroendocrine secretory protein 55-like
102887497 ADCY1; adenylate cyclase type 1
102893265 ADCY2; adenylate cyclase type 2
102886232 ADCY3; adenylate cyclase type 3
102890575 ADCY4; adenylate cyclase type 4
102897495 ADCY5; adenylate cyclase type 5
102890588 ADCY6; adenylate cyclase type 6 isoform X2
102881535 ADCY7; adenylate cyclase type 7
102896789 ADCY8; adenylate cyclase type 8 isoform X1
102885676 ADCY9; adenylate cyclase type 9
102886679 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha
102877853 PRKACB; cAMP-dependent protein kinase catalytic subunit beta isoform X1
102883771 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
102882744 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
102893506 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
102890410 GNB4; guanine nucleotide-binding protein subunit beta-4
102881664 GNB5; guanine nucleotide-binding protein subunit beta-5
102886028 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
102888735 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
102889599 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
102879439 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
102886041 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
112479655 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 isoform X1
107196679 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
102898925 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
102886682 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
102877921 GNG14; putative guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-14
102892764 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 isoform X6
102898674 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
102881686 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
102879139 COL4A3; LOW QUALITY PROTEIN: collagen alpha-3(IV) chain
102879385 COL4A4; collagen alpha-4(IV) chain
102898331 COL4A1; LOW QUALITY PROTEIN: collagen alpha-1(IV) chain
102891781 COL4A5; collagen alpha-5(IV) chain isoform X1
102895248 COL4A6; collagen alpha-6(IV) chain
102898083 COL4A2; collagen alpha-2(IV) chain
102894718 LAMA2; laminin subunit alpha-2 isoform X1
102884860 LAMA1; laminin subunit alpha-1 isoform X1
102897225 LAMA3; laminin subunit alpha-3 isoform X6
102892706 LAMA5; laminin subunit alpha-5
102877962 LAMA4; laminin subunit alpha-4
102881611 LAMB1; laminin subunit beta-1 isoform X1
102889392 LAMB2; laminin subunit beta-2 isoform X1
102896504 LAMB3; laminin subunit beta-3
102896150 LAMB4; laminin subunit beta-4
102885413 LAMC1; laminin subunit gamma-1
102892078 LAMC2; laminin subunit gamma-2
102881476 LAMC3; laminin subunit gamma-3
102891509 FN1; fibronectin isoform X1
102897185 ITGA2; integrin alpha-2 isoform X1
102883900 ITGA2B; integrin alpha-IIb
102884713 ITGA3; integrin alpha-3 isoform X1
102883425 ITGA6; integrin alpha-6 isoform X1
102895440 ITGAV; integrin alpha-V
102886785 ITGB1; integrin beta-1
102898998 PTK2; focal adhesion kinase 1
102889227 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
102880320 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
102889576 PIK3CD; LOW QUALITY PROTEIN: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
102879163 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1
102891637 phosphatidylinositol 3-kinase regulatory subunit gamma isoform X3
102879453 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
102881949 PTEN; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X1
102880253 NKX3-1; homeobox protein Nkx-3.1
102885144 AKT1; RAC-alpha serine/threonine-protein kinase isoform X1
102879337 AKT3; RAC-gamma serine/threonine-protein kinase isoform X1
102898305 AKT2; LOW QUALITY PROTEIN: RAC-beta serine/threonine-protein kinase
102879469 CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
102893261 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1
102880203 IKBKG; NF-kappa-B essential modulator isoform X1
102891056 NFKBIA; NF-kappa-B inhibitor alpha
102880692 NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1
102894780 NFKB2; nuclear factor NF-kappa-B p100 subunit isoform X1
102878395 RELA; transcription factor p65
102886561 PTGS2; prostaglandin G/H synthase 2
102878456 NOS2; nitric oxide synthase, inducible
102896443 BCL2; apoptosis regulator Bcl-2
102884388 baculoviral IAP repeat-containing protein 3
102884651 BIRC2; baculoviral IAP repeat-containing protein 2 isoform X1
102885349 XIAP; E3 ubiquitin-protein ligase XIAP
102889019 BIRC7; LOW QUALITY PROTEIN: baculoviral IAP repeat-containing protein 7
102887704 BCL2L1; bcl-2-like protein 1
102894412 TRAF1; TNF receptor-associated factor 1
102889343 TRAF2; TNF receptor-associated factor 2 isoform X1
102881091 TRAF3; TNF receptor-associated factor 3
102896659 TRAF4; TNF receptor-associated factor 4 isoform X1
102879730 TRAF5; TNF receptor-associated factor 5 isoform X1
102886476 TRAF6; TNF receptor-associated factor 6 isoform X1
102885092 MTOR; serine/threonine-protein kinase mTOR
102891214 RPS6KB2; ribosomal protein S6 kinase beta-2 isoform X1
102889369 RPS6KB1; ribosomal protein S6 kinase beta-1 isoform X1
102877892 BAD; bcl2-associated agonist of cell death isoform X1
102892244 FOXO1; forkhead box protein O1
102884281 MDM2; E3 ubiquitin-protein ligase Mdm2
102889604 TP53; cellular tumor antigen p53
102880085 CDKN1B; cyclin-dependent kinase inhibitor 1B
102894049 CDKN1A; cyclin-dependent kinase inhibitor 1
102897172 BCR; breakpoint cluster region protein
102895947 ABL1; tyrosine-protein kinase ABL1
102898080 CRKL; crk-like protein
102885553 CRK; adapter molecule crk isoform X1
102895335 CBL; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase CBL
102884638 signal transducer and activator of transcription 5A
102884882 signal transducer and activator of transcription 5B isoform X1
102891826 PIM1; serine/threonine-protein kinase pim-1
102886532 PIM2; serine/threonine-protein kinase pim-2
102885643 KNG1; kininogen-1 isoform X1
102895320 EDN1; endothelin-1
102895893 B2 bradykinin receptor isoform X1
102898148 EDNRA; endothelin-1 receptor
102880014 EDNRB; endothelin receptor type B
102877919 guanine nucleotide-binding protein G(q) subunit alpha
102888619 GNA11; guanine nucleotide-binding protein subunit alpha-11
102879238 PLCB3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3
102885207 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1
102885781 PLCB1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1
102885953 PLCB2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2
102887078 PRKCA; protein kinase C alpha type
102880663 PRKCB; protein kinase C beta type
102888961 PRKCG; protein kinase C gamma type
102895516 IL2; interleukin-2
102896574 interleukin-3
102890025 IL4; interleukin-4
102890771 IL5; interleukin-5
102895746 IL6; interleukin-6
112472586 IL7; interleukin-7
102887571 IL12A; interleukin-12 subunit alpha
102884214 IL12B; interleukin-12 subunit beta
102890275 IL13; interleukin-13
102887558 IL15; interleukin-15 isoform X2
102879394 IL23A; interleukin-23 subunit alpha
102883166 EPO; erythropoietin
102893886 interferon alpha-1
102890009 interferon alpha-4
102882436 IFNG; interferon gamma precursor
102891511 IL2RA; interleukin-2 receptor subunit alpha
102883396 IL2RB; interleukin-2 receptor subunit beta
102888070 IL2RG; cytokine receptor common subunit gamma
102878242 IL3RA; interleukin-3 receptor subunit alpha
102882815 IL4R; interleukin-4 receptor subunit alpha isoform X1
102897194 CSF2RB; cytokine receptor common subunit beta
102896000 IL5RA; interleukin-5 receptor subunit alpha
102878027 IL6R; interleukin-6 receptor subunit alpha
102880415 IL6ST; interleukin-6 receptor subunit beta isoform X1
102889092 IL7R; interleukin-7 receptor subunit alpha
102878946 IL12RB1; interleukin-12 receptor subunit beta-1 isoform X1
102885605 IL12RB2; interleukin-12 receptor subunit beta-2
102897874 IL13RA1; interleukin-13 receptor subunit alpha-1
102892156 IL15RA; interleukin-15 receptor subunit alpha
102885363 IL23R; interleukin-23 receptor
102886625 EPOR; erythropoietin receptor
102892040 IFNAR1; interferon alpha/beta receptor 1
102891485 IFNAR2; interferon alpha/beta receptor 2 isoform X1
102888010 IFNGR1; interferon gamma receptor 1
102877930 IFNGR2; interferon gamma receptor 2
102879824 EML4; echinoderm microtubule-associated protein-like 4 isoform X1
102884662 ALK; ALK tyrosine kinase receptor
102877927 RASGRP1; RAS guanyl-releasing protein 1 isoform X1
102896690 RASGRP2; RAS guanyl-releasing protein 2
102888491 RASGRP3; ras guanyl-releasing protein 3
102885173 RASGRP4; RAS guanyl-releasing protein 4 isoform X1
102880365 JAK1; tyrosine-protein kinase JAK1 isoform X1
102882079 JAK2; tyrosine-protein kinase JAK2
102898620 JAK3; tyrosine-protein kinase JAK3
102884374 STAT3; LOW QUALITY PROTEIN: signal transducer and activator of transcription 3
102886603 STAT1; signal transducer and activator of transcription 1-alpha/beta
102879640 STAT2; signal transducer and activator of transcription 2
102886854 STAT4; signal transducer and activator of transcription 4
102885160 STAT6; signal transducer and activator of transcription 6 isoform X1
102890394 VEGFA; vascular endothelial growth factor A isoform X2
102883443 vascular endothelial growth factor B
102882963 VEGFB; vascular endothelial growth factor B
102889783 PGF; placenta growth factor isoform X1
102889143 VEGFD; vascular endothelial growth factor D
102884251 VEGFC; vascular endothelial growth factor C
102887662 TGFA; protransforming growth factor alpha isoform X1
102891552 EGF; pro-epidermal growth factor isoform X1
102893495 EGFR; epidermal growth factor receptor
102885300 ERBB2; LOW QUALITY PROTEIN: receptor tyrosine-protein kinase erbB-2
102893670 PDGFA; platelet-derived growth factor subunit A
102897699 PDGFB; platelet-derived growth factor subunit B isoform X1
102895362 PDGFRA; platelet-derived growth factor receptor alpha isoform X1
102887643 PDGFRB; platelet-derived growth factor receptor beta isoform X1
102890331 IGF1; insulin-like growth factor I isoform X3
102880410 IGF2; insulin-like growth factor II
102885962 IGF1R; insulin-like growth factor 1 receptor
102884034 KITLG; kit ligand isoform X1
102895969 KIT; mast/stem cell growth factor receptor Kit
102881080 FLT3LG; fms-related tyrosine kinase 3 ligand isoform X1
102891572 FLT3; receptor-type tyrosine-protein kinase FLT3
102884470 HGF; hepatocyte growth factor isoform X1
102885990 MET; hepatocyte growth factor receptor isoform X1
102894192 FGF1; fibroblast growth factor 1 isoform X1
107196088 FGF2; fibroblast growth factor 2
102895922 FGF10; fibroblast growth factor 10
102887777 FGF7; fibroblast growth factor 7
102892141 FGF6; fibroblast growth factor 6
102895642 FGF5; fibroblast growth factor 5
102890153 FGF16; fibroblast growth factor 16
102893226 FGF8; fibroblast growth factor 8 isoform X4
102894115 FGF18; fibroblast growth factor 18
102888098 FGF20; fibroblast growth factor 20
102893244 FGF4; fibroblast growth factor 4
102894279 FGF17; fibroblast growth factor 17 isoform X1
102887882 FGF9; fibroblast growth factor 9
102896895 FGF22; fibroblast growth factor 22
102885081 FGF19; fibroblast growth factor 19
102886540 FGF21; fibroblast growth factor 21
102883346 FGF23; fibroblast growth factor 23
102898943 FGFR1; fibroblast growth factor receptor 1 isoform X9
102882899 FGFR2; fibroblast growth factor receptor 2 isoform X8
102878342 FGFR3; fibroblast growth factor receptor 3
102879288 FGFR4; fibroblast growth factor receptor 4 isoform X3
102878822 GRB2; growth factor receptor-bound protein 2 isoform X1
102882462 SOS1; son of sevenless homolog 1 isoform X1
102889597 SOS2; son of sevenless homolog 2
102896270 HRAS; GTPase HRas isoform X3
102895590 KRAS; GTPase KRas isoform X1
102885950 NRAS; GTPase NRas isoform X2
102877877 ARAF; serine/threonine-protein kinase A-Raf isoform X2
102878393 BRAF; serine/threonine-protein kinase B-raf isoform X2
102893439 RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X1
102897122 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 isoform X1
102879034 MAP2K2; dual specificity mitogen-activated protein kinase kinase 2
102895390 MAPK1; mitogen-activated protein kinase 1
102885749 MAPK3; mitogen-activated protein kinase 3
102896121 JUN; transcription factor AP-1
102891428 FOS; proto-oncogene c-Fos
102893422 ETS1; protein C-ets-1
102893881 MMP1; interstitial collagenase
102883808 MMP2; 72 kDa type IV collagenase
102889517 MMP9; matrix metalloproteinase-9
102892534 CXCL8; interleukin-8
102894222 CDK4; cyclin-dependent kinase 4
102897813 RPS6KA5; ribosomal protein S6 kinase alpha-5
102878133 RET; proto-oncogene tyrosine-protein kinase receptor Ret isoform X4
102879174 CCDC6; coiled-coil domain-containing protein 6
102896808 NCOA4; nuclear receptor coactivator 4 isoform X3
112472150 NTRK1; high affinity nerve growth factor receptor
102898874 TPM3; tropomyosin alpha-3 chain isoform X1
102887317 TPR; LOW QUALITY PROTEIN: nucleoprotein TPR
102892687 TFG; protein TFG isoform X1
102879898 RASSF1; ras association domain-containing protein 1 isoform X1
102888616 RASSF5; ras association domain-containing protein 5 isoform X2
102881410 STK4; serine/threonine-protein kinase 4 isoform X1
102892714 DAPK3; death-associated protein kinase 3
102885201 DAPK2; death-associated protein kinase 2 isoform X2
102891860 DAPK1; death-associated protein kinase 1
102896228 PLCG1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1
102883128 PLCG2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
102878877 ELK1; ETS domain-containing protein Elk-1 isoform X1
102894226 CALM2; calmodulin-2 isoform X1
102897273 CALM3; calmodulin-3
102886058 CALM1; calmodulin-1
102884196 CALML6; calmodulin-like protein 6
102891673 calmodulin-like
102893109 CALML4; LOW QUALITY PROTEIN: calmodulin-like protein 4
102881744 calmodulin-like
102888982 CAMK2B; calcium/calmodulin-dependent protein kinase type II subunit beta
102888385 CAMK2A; calcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1
102880869 CAMK2D; calcium/calmodulin-dependent protein kinase type II subunit delta
102896030 CAMK2G; calcium/calmodulin-dependent protein kinase type II subunit gamma
102880177 RALGDS; ral guanine nucleotide dissociation stimulator isoform X2
102898811 RALA; ras-related protein Ral-A
102899030 RALB; ras-related protein Ral-B
102890515 RALBP1; ralA-binding protein 1 isoform X1
102889114 CDC42; cell division control protein 42 homolog
102897644 RAC1; ras-related C3 botulinum toxin substrate 1 isoform X1
102885507 RAC2; ras-related C3 botulinum toxin substrate 2
102887421 RAC3; ras-related C3 botulinum toxin substrate 3
102884736 PLD1; phospholipase D1 isoform X1
102894598 PLD2; phospholipase D2 isoform X1
102885064 MAPK10; mitogen-activated protein kinase 10 isoform X5
102890689 MAPK9; mitogen-activated protein kinase 9 isoform X1
102892777 MAPK8; mitogen-activated protein kinase 8 isoform X1
102894983 PAX8; paired box protein Pax-8 isoform X1
102892450 PPARG; peroxisome proliferator-activated receptor gamma isoform X1
102881572 RXRA; retinoic acid receptor RXR-alpha
102888877 RXRB; retinoic acid receptor RXR-beta isoform X1
102897820 RXRG; retinoic acid receptor RXR-gamma
102886545 RARB; retinoic acid receptor beta
102877910 ESR1; estrogen receptor isoform X1
102878324 ESR2; estrogen receptor beta isoform X2
102885576 NCOA1; nuclear receptor coactivator 1 isoform X1
102892705 NCOA3; nuclear receptor coactivator 3 isoform X1
102894100 SP1; transcription factor Sp1 isoform X1
102898485 PPARD; peroxisome proliferator-activated receptor delta isoform X2
102890702 JUP; junction plakoglobin isoform X2
102881382 ZBTB16; zinc finger and BTB domain-containing protein 16 isoform X1
102880130 RARA; retinoic acid receptor alpha isoform X1
102890664 CCNA1; cyclin-A1
102894080 CCNA2; cyclin-A2
102895190 PML; protein PML isoform X3
102879444 RUNX1; runt-related transcription factor 1
102888477 RUNX1T1; protein CBFA2T1 isoform X1
102880490 SPI1; transcription factor PU.1
102893139 CEBPA; CCAAT/enhancer-binding protein alpha
102878494 granulocyte-macrophage colony-stimulating factor receptor subunit alpha
102897878 CSF3R; granulocyte colony-stimulating factor receptor isoform X1
102886964 CSF1R; macrophage colony-stimulating factor 1 receptor
102896422 LOW QUALITY PROTEIN: cyclin-dependent kinase inhibitor 2A
102895276 E2F1; transcription factor E2F1
102884459 E2F2; transcription factor E2F2 isoform X1
102887239 E2F3; transcription factor E2F3 isoform X1
102881979 MAX; protein max isoform X2
102877831 ZBTB17; zinc finger and BTB domain-containing protein 17
102893142 CDKN2B; cyclin-dependent kinase 4 inhibitor B
102896272 CDK6; cyclin-dependent kinase 6
102892640 CCND2; G1/S-specific cyclin-D2
102881884 CCND3; G1/S-specific cyclin-D3
102894196 CKS1B; cyclin-dependent kinases regulatory subunit 1
102879697 CKS2; cyclin-dependent kinases regulatory subunit 2
102885538 SKP1; S-phase kinase-associated protein 1
102887109 CUL1; cullin-1
102893437 RBX1; E3 ubiquitin-protein ligase RBX1
102880695 SKP2; S-phase kinase-associated protein 2
102893397 CDK2; cyclin-dependent kinase 2 isoform X1
102882411 CCNE2; G1/S-specific cyclin-E2 isoform X1
102882260 CCNE1; LOW QUALITY PROTEIN: G1/S-specific cyclin-E1
102893019 RB1; retinoblastoma-associated protein
102886440 GADD45A; growth arrest and DNA damage-inducible protein GADD45 alpha
102878191 GADD45G; growth arrest and DNA damage-inducible protein GADD45 gamma
102885790 GADD45B; growth arrest and DNA damage-inducible protein GADD45 beta
102885135 BAX; apoptosis regulator BAX isoform X1
102883540 BAK1; bcl-2 homologous antagonist/killer
102879479 DDB2; DNA damage-binding protein 2 isoform X1
102890888 POLK; DNA polymerase kappa isoform X1
102895256 TERT; telomerase reverse transcriptase
102899015 MITF; microphthalmia-associated transcription factor isoform X1
102884154 TGFB1; transforming growth factor beta-1
102881295 TGFB2; transforming growth factor beta-2 isoform X2
102893304 TGFB3; transforming growth factor beta-3
102880759 TGFBR1; TGF-beta receptor type-1 isoform X2
102889618 TGFBR2; TGF-beta receptor type-2 isoform X1
102893928 SMAD2; mothers against decapentaplegic homolog 2
102895268 SMAD3; mothers against decapentaplegic homolog 3
102886521 SMAD4; mothers against decapentaplegic homolog 4
102878481 MECOM; MDS1 and EVI1 complex locus protein isoform X1
102899024 CTBP1; C-terminal-binding protein 1 isoform X1
102879836 CTBP2; C-terminal-binding protein 2 isoform X3
102890938 HDAC1; histone deacetylase 1
102878536 HDAC2; histone deacetylase 2
102898392 MLH1; DNA mismatch repair protein Mlh1 isoform X1
102893728 MSH2; DNA mismatch repair protein Msh2 isoform X3
102878992 MSH3; DNA mismatch repair protein Msh3 isoform X1
102892999 MSH6; DNA mismatch repair protein Msh6
102896802 BRCA2; breast cancer type 2 susceptibility protein
102894016 RAD51; DNA repair protein RAD51 homolog 1
102883204 FASLG; tumor necrosis factor ligand superfamily member 6
102879561 FAS; tumor necrosis factor receptor superfamily member 6 isoform X5
102892511 FADD; FAS-associated death domain protein
102878181 CASP8; caspase-8
102887379 BID; BH3-interacting domain death agonist isoform X3
102894490 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
102892591 BBC3; bcl-2-binding component 3
102890309 BCL2L11; bcl-2-like protein 11 isoform X1
102879159 cytochrome c
102893036 cytochrome c, testis-specific-like
102897687 APAF1; apoptotic protease-activating factor 1
102879606 CASP7; caspase-7
102894870 KEAP1; kelch-like ECH-associated protein 1
102892042 NFE2L2; nuclear factor erythroid 2-related factor 2 isoform X1
102880347 HMOX1; LOW QUALITY PROTEIN: heme oxygenase 1
102889138 NQO1; NAD(P)H dehydrogenase [quinone] 1
102885225 MGST2; microsomal glutathione S-transferase 2
102886852 GSTO2; glutathione S-transferase omega-2
102887110 GSTO1; glutathione S-transferase omega-1
102887332 MGST1; microsomal glutathione S-transferase 1
102891202 MGST3; microsomal glutathione S-transferase 3
102891351 GSTA4; glutathione S-transferase A4
102897012 glutathione S-transferase A3-like
102883042 glutathione S-transferase theta-1
102883292 glutathione S-transferase theta-3
102893685 GSTM4; glutathione S-transferase Mu 4 isoform X3
102894088 glutathione S-transferase Mu 5
102891589 glutathione S-transferase A4
107195441 glutathione S-transferase theta-1
102882795 glutathione S-transferase theta-4
102889068 glutathione S-transferase P isoform X2
102896271 glutathione S-transferase P
102887506 TXNRD1; thioredoxin reductase 1, cytoplasmic
102894141 TXNRD3; thioredoxin reductase 3
102890334 TXNRD2; thioredoxin reductase 2, mitochondrial isoform X2
102884716 von Hippel-Lindau disease tumor suppressor-like
102895455 ELOC; elongin-C
102895498 ELOB; elongin-B
102895656 CUL2; cullin-2 isoform X2
102894690 EGLN1; egl nine homolog 1
102886969 EGLN3; egl nine homolog 3
102881942 EGLN2; egl nine homolog 2 isoform X2
102881861 FH; fumarate hydratase, mitochondrial isoform X1
102897284 HIF1A; hypoxia-inducible factor 1-alpha
102894133 EPAS1; endothelial PAS domain-containing protein 1 isoform X1
102885691 ARNT; aryl hydrocarbon receptor nuclear translocator isoform X1
102895548 ARNT2; aryl hydrocarbon receptor nuclear translocator 2 isoform X8
102886172 CREBBP; LOW QUALITY PROTEIN: CREB-binding protein
102881042 EP300; histone acetyltransferase p300
102885620 SLC2A1; solute carrier family 2, facilitated glucose transporter member 1
102883084 JAG1; protein jagged-1
102891267 JAG2; protein jagged-2
102891557 DLL4; delta-like protein 4 isoform X2
102882856 DLL3; delta-like protein 3
102892930 DLL1; delta-like protein 1
102889752 NOTCH1; neurogenic locus notch homolog protein 1
102887446 NOTCH2; LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 2
102898799 NOTCH3; neurogenic locus notch homolog protein 3
102895453 NOTCH4; neurogenic locus notch homolog protein 4
102890128 HES1; transcription factor HES-1
102893116 HES5; transcription factor HES-5
102893208 hairy/enhancer-of-split related with YRPW motif protein 1
102891586 HEY2; hairy/enhancer-of-split related with YRPW motif protein 2
102895448 HEYL; hairy/enhancer-of-split related with YRPW motif-like protein
102889771 FLT4; vascular endothelial growth factor receptor 3
102882514 SHH; sonic hedgehog protein
102884350 PTCH1; LOW QUALITY PROTEIN: protein patched homolog 1
102892668 SMO; smoothened homolog
102882111 KIF7; kinesin-like protein KIF7
102892289 SUFU; suppressor of fused homolog isoform X1
102889893 GLI1; zinc finger protein GLI1 isoform X1
102880962 GLI2; zinc finger protein GLI2 isoform X1
102894872 GLI3; transcriptional activator GLI3 isoform X1
102886941 BMP2; bone morphogenetic protein 2
102881920 BMP4; bone morphogenetic protein 4 isoform X1
102880475 HHIP; hedgehog-interacting protein
102887248 PTCH2; protein patched homolog 2
102893723 LOW QUALITY PROTEIN: androgen receptor-like
102894221 AR; androgen receptor
102879632 HSP90AA1; heat shock protein HSP 90-alpha
102887985 HSP90AB1; heat shock protein HSP 90-beta
102889156 HSP90B1; endoplasmin
|
K06765 DCC; deleted in colorectal carcinoma
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K08733 APPL1; DCC-interacting protein 13 alpha
K05689 CDH1; cadherin 1, type 1, E-cadherin
K02105 CTNNB1; catenin beta 1
K05691 CTNNA; catenin alpha
K05691 CTNNA; catenin alpha
K05691 CTNNA; catenin alpha
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02085 APC; adenomatosis polyposis coli protein
K02085 APC; adenomatosis polyposis coli protein
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K08731 BIRC5; baculoviral IAP repeat-containing protein 5
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; G1/S-specific cyclin-D1
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7; frizzled 1/7
K02432 FZD1_7; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4; frizzled 4
K02375 FZD5_8; frizzled 5/8
K02375 FZD5_8; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10; frizzled 9/10
K02842 FZD9_10; frizzled 9/10
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K03069 FRAT1; frequently rearranged in advanced T-cell lymphomas 1
K01313 F2; coagulation factor II (thrombin) [EC:3.4.21.5]
K09821 AGT; angiotensinogen
K03914 F2R; coagulation factor II (thrombin) receptor
K04236 F2RL3; coagulation factor II (thrombin) receptor-like 3
K04289 LPAR1; lysophosphatidic acid receptor 1
K04291 LPAR2; lysophosphatidic acid receptor 2
K04294 LPAR3; lysophosphatidic acid receptor 3
K04275 LPAR4; lysophosphatidic acid receptor 4
K08390 LPAR5; lysophosphatidic acid receptor 5
K04273 LPAR6; lysophosphatidic acid receptor 6
K04166 AGTR1; angiotensin II receptor type 1
K04346 GNA12; guanine nucleotide-binding protein subunit alpha-12
K04639 GNA13; guanine nucleotide-binding protein subunit alpha-13
K07532 ARHGEF12; Rho guanine nucleotide exchange factor 12
K12331 ARHGEF11; Rho guanine nucleotide exchange factor 11
K12330 ARHGEF1; Rho guanine nucleotide exchange factor 1
K19464 PLEKHG5; pleckstrin homology domain-containing family G member 5
K04513 RHOA; Ras homolog gene family, member A
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K10031 CXCL12; C-X-C motif chemokine 12
K04189 CXCR4; C-X-C chemokine receptor type 4
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04258 PTGER1; prostaglandin E receptor 1
K04259 PTGER2; prostaglandin E receptor 2
K04260 PTGER3; prostaglandin E receptor 3
K04261 PTGER4; prostaglandin E receptor 4
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K05637 LAMA1_2; laminin, alpha 1/2
K05637 LAMA1_2; laminin, alpha 1/2
K06240 LAMA3_5; laminin, alpha 3/5
K06240 LAMA3_5; laminin, alpha 3/5
K06241 LAMA4; laminin, alpha 4
K05636 LAMB1; laminin, beta 1
K06243 LAMB2; laminin, beta 2
K06244 LAMB3; laminin, beta 3
K06245 LAMB4; laminin, beta 4
K05635 LAMC1; laminin, gamma 1
K06246 LAMC2; laminin, gamma 2
K06247 LAMC3; laminin, gamma 3
K05717 FN1; fibronectin 1
K06481 ITGA2; integrin alpha 2
K06476 ITGA2B; integrin alpha 2B
K06482 ITGA3; integrin alpha 3
K06485 ITGA6; integrin alpha 6
K06487 ITGAV; integrin alpha V
K05719 ITGB1; integrin beta 1
K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K09348 NKX3-1; homeobox protein Nkx-3.1
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04469 NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
K04735 RELA; transcription factor p65
K11987 PTGS2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
K02161 BCL2; apoptosis regulator Bcl-2
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04725 XIAP; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K16061 BIRC7_8; baculoviral IAP repeat-containing protein 7/8
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K03172 TRAF1; TNF receptor-associated factor 1
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K03174 TRAF3; TNF receptor-associated factor 3
K09848 TRAF4; TNF receptor-associated factor 4
K09849 TRAF5; TNF receptor-associated factor 5
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K07201 FOXO1; forkhead box protein O1
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53; tumor protein p53
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K08878 BCR1; breakpoint cluster region protein [EC:2.7.11.1]
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K04438 CRK; C-crk adapter molecule crk
K04438 CRK; C-crk adapter molecule crk
K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K04702 PIM1; proto-oncogene serine/threonine-protein kinase Pim-1 [EC:2.7.11.1]
K08806 PIM2; proto-oncogene serine/threonine-protein kinase Pim-2 [EC:2.7.11.1]
K03898 KNG; kininogen
K16366 EDN1; endothelin-1
K03916 BDKRB2; bradykinin receptor B2
K04197 EDNRA; endothelin receptor type A
K04198 EDNRB; endothelin receptor type B
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K05429 IL2; interleukin 2
K04736 IL3; interleukin 3
K05430 IL4; interleukin 4
K05428 IL5; interleukin 5
K05405 IL6; interleukin 6
K05431 IL7; interleukin 7
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05435 IL13; interleukin 13
K05433 IL15; interleukin 15
K05426 IL23A; interleukin 23 subunit alpha
K05437 EPO; erythropoietin
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K04687 IFNG; interferon gamma
K05068 IL2RA; interleukin 2 receptor alpha
K05069 IL2RB; interleukin 2 receptor beta
K05070 IL2RG; interleukin 2 receptor gamma
K04737 IL3RA; interleukin 3 receptor alpha
K05071 IL4R; interleukin 4 receptor
K04738 CSF2RB; cytokine receptor common subunit beta
K05067 IL5RA; interleukin 5 receptor alpha
K05055 IL6R; interleukin 6 receptor
K05060 IL6ST; interleukin 6 signal transducer
K05072 IL7R; interleukin 7 receptor
K05063 IL12RB1; interleukin 12 receptor beta-1
K05064 IL12RB2; interleukin 12 receptor beta-2
K05076 IL13RA1; interleukin 13 receptor alpha-1
K05074 IL15RA; interleukin 15 receptor alpha
K05065 IL23R; interleukin 23 receptor
K05079 EPOR; erythropoietin receptor
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K05132 IFNGR1; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K15420 EML4; echinoderm microtubule-associated protein-like 4
K05119 ALK; anaplastic lymphoma kinase [EC:2.7.10.1]
K04350 RASGRP1; RAS guanyl-releasing protein 1
K12361 RASGRP2; RAS guanyl-releasing protein 2
K12362 RASGRP3; RAS guanyl-releasing protein 3
K12363 RASGRP4; RAS guanyl-releasing protein 4
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K11222 STAT4; signal transducer and activator of transcription 4
K11225 STAT6; signal transducer and activator of transcription 6
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K16858 VEGFB; vascular endothelial growth factor B
K16859 PGF; placenta growth factor
K05449 VEGFC_D; vascular endothelial growth factor C/D
K05449 VEGFC_D; vascular endothelial growth factor C/D
K08774 TGFA; transforming growth factor, alpha
K04357 EGF; epidermal growth factor
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K04363 PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05459 IGF1; insulin-like growth factor 1
K13769 IGF2; insulin-like growth factor 2
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K05461 KITLG; KIT ligand
K05091 KIT; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K05454 FLT3LG; fms-related tyrosine kinase 3 ligand
K05092 FLT3; fms-related tyrosine kinase 3 [EC:2.7.10.1]
K05460 HGF; hepatocyte growth factor
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K04362 FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04379 FOS; proto-oncogene protein c-fos
K02678 ETS1; C-ets-1
K01388 MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
K01398 MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K10030 IL8; interleukin 8
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K04445 RPS6KA5; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
K05126 RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
K09288 CCDC6; coiled-coil domain-containing protein 6
K09289 NCOA4; nuclear receptor coactivator 4
K03176 NTRK1; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K09290 TPM3; tropomyosin 3
K09291 TPR; nucleoprotein TPR
K09292 TFG; protein TFG
K09850 RASSF1; Ras association domain-containing protein 1
K08015 RASSF5; Ras association domain-containing protein 5
K04411 STK4; serine/threonine kinase 4
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K04375 ELK1; ETS domain-containing protein Elk-1
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K07834 RALA; Ras-related protein Ral-A
K07835 RALB; Ras-related protein Ral-B
K08773 RALBP1; RalA-binding protein 1
K04393 CDC42; cell division control protein 42
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K09293 PAX8; paired box protein 8
K08530 NR1C3; peroxisome proliferator-activated receptor gamma
K08524 RXRA; retinoid X receptor alpha
K08525 RXRB; retinoid X receptor beta
K08526 RXRG; retinoid X receptor gamma
K08528 RARB; retinoic acid receptor beta
K08550 ESR1; estrogen receptor alpha
K08551 ESR2; estrogen receptor beta
K09101 NCOA1; nuclear receptor coactivator 1 [EC:2.3.1.48]
K11256 NCOA3; nuclear receptor coactivator 3 [EC:2.3.1.48]
K04684 SP1; transcription factor Sp1
K04504 NR1C2; peroxisome proliferator-activated receptor delta
K10056 JUP; junction plakoglobin
K10055 ZBTB16; zinc finger and BTB domain-containing protein 16
K08527 RARA; retinoic acid receptor alpha
K06627 CCNA; cyclin-A
K06627 CCNA; cyclin-A
K10054 PML; E3 SUMO-protein ligase PML [EC:2.3.2.-]
K08367 RUNX1; runt-related transcription factor 1
K10053 RUNX1T1; CBFA2/RNUX1 translocation partner 1
K09438 SPI1; transcription factor PU.1
K09055 CEBPA; CCAAT/enhancer binding protein (C/EBP), alpha
K05066 CSF2RA; granulocyte-macrophage colony-stimulating factor receptor alpha
K05061 CSF3R; granulocyte colony-stimulating factor receptor
K05090 CSF1R; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04453 MAX; Max protein
K10500 ZBTB17; zinc finger and BTB domain-containing protein 17
K04685 CDKN2B; cyclin-dependent kinase inhibitor 2B
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K02219 CKS1; cyclin-dependent kinase regulatory subunit CKS1
K02219 CKS1; cyclin-dependent kinase regulatory subunit CKS1
K03094 SKP1; S-phase kinase-associated protein 1
K03347 CUL1; cullin 1
K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
K03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K06618 RB1; retinoblastoma-associated protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]
K09455 MITF; microphthalmia-associated transcription factor
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04462 MECOM; [histone H3]-lysine9 N-methyltransferase (ecotropic virus integration site 1 protein) [EC:2.1.1.367]
K04496 CTBP; C-terminal binding protein [EC:1.1.1.428]
K04496 CTBP; C-terminal binding protein [EC:1.1.1.428]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K08734 MLH1; DNA mismatch repair protein MLH1
K08735 MSH2; DNA mismatch repair protein MSH2
K08736 MSH3; DNA mismatch repair protein MSH3
K08737 MSH6; DNA mismatch repair protein MSH6
K08775 BRCA2; breast cancer 2 susceptibility protein
K04482 RAD51; DNA repair protein RAD51
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K10131 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
K10132 BBC3; Bcl-2-binding component 3
K16341 BCL2L11; Bcl-2-like protein 11
K08738 CYC; cytochrome c
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04397 CASP7; caspase 7 [EC:3.4.22.60]
K10456 KLHL19; kelch-like protein 19
K05638 NFE2L2; nuclear factor erythroid 2-related factor 2
K00510 HMOX1; heme oxygenase 1 [EC:1.14.14.18]
K00355 NQO1; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K23790 GSTP; glutathione S-transferase P [EC:2.5.1.18]
K23790 GSTP; glutathione S-transferase P [EC:2.5.1.18]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K03871 VHL; von Hippel-Lindau disease tumor supressor
K03872 ELOC; elongin-C
K03873 ELOB; elongin-B
K03870 CUL2; cullin 2
K09592 EGLN; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K09592 EGLN; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K09592 EGLN; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K09095 HIF2A; hypoxia-inducible factor 2 alpha
K09097 ARNT; aryl hydrocarbon receptor nuclear translocator
K15589 ARNT2; aryl hydrocarbon receptor nuclear translocator 2
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K07299 SLC2A1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
K06052 JAG1; jagged-1
K21635 JAG2; jagged-2
K06051 DLL; delta
K06051 DLL; delta
K06051 DLL; delta
K02599 NOTCH1; Notch 1
K20994 NOTCH2; Notch 2
K20995 NOTCH3; Notch 3
K20996 NOTCH4; Notch 4
K06054 HES1; hairy and enhancer of split 1
K06055 HES5; hairy and enhancer of split 5
K09091 HEY; hairy and enhancer of split related with YRPW motif
K09091 HEY; hairy and enhancer of split related with YRPW motif
K09091 HEY; hairy and enhancer of split related with YRPW motif
K05097 FLT4; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K11988 SHH; sonic hedgehog
K06225 PTCH1; patched 1
K06226 SMO; smoothened
K18806 KIF7; kinesin family member 7
K06229 SUFU; suppressor of fused
K16797 GLI1; zinc finger protein GLI1
K16798 GLI2; zinc finger protein GLI2
K06230 GLI3; zinc finger protein GLI3
K21283 BMP2; bone morphogenetic protein 2
K04662 BMP4; bone morphogenetic protein 4
K06231 HHIP; hedgehog interacting protein
K11101 PTCH2; patched 2
K08557 AR; androgen receptor
K08557 AR; androgen receptor
K04079 HSP90A; molecular chaperone HtpG
K04079 HSP90A; molecular chaperone HtpG
K09487 HSP90B; heat shock protein 90kDa beta
|
05202 Transcriptional misregulation in cancer [PATH:pale05202]
|
102879444 RUNX1; runt-related transcription factor 1
102886964 CSF1R; macrophage colony-stimulating factor 1 receptor
102883356 MPO; myeloperoxidase
102893042 CSF2; granulocyte-macrophage colony-stimulating factor
102896574 interleukin-3
102888477 RUNX1T1; protein CBFA2T1 isoform X1
102890938 HDAC1; histone deacetylase 1
102878536 HDAC2; histone deacetylase 2
102886781 SIN3A; paired amphipathic helix protein Sin3a
102894128 NCOR1; nuclear receptor corepressor 1
102893139 CEBPA; CCAAT/enhancer-binding protein alpha
102896517 PER2; LOW QUALITY PROTEIN: period circadian protein homolog 2
102880490 SPI1; transcription factor PU.1
102885041 CD14; monocyte differentiation antigen CD14
102889241 ITGAM; integrin alpha-M
102889680 FCGR1A; high affinity immunoglobulin gamma Fc receptor I
102890702 JUP; junction plakoglobin isoform X2
102895190 PML; protein PML isoform X3
102880130 RARA; retinoic acid receptor alpha isoform X1
102890664 CCNA1; cyclin-A1
102894080 CCNA2; cyclin-A2
102883309 CEBPE; CCAAT/enhancer-binding protein epsilon
102896489 bcl-2-related protein A1 isoform X6
102881382 ZBTB16; zinc finger and BTB domain-containing protein 16 isoform X1
102895524 MYC; myc proto-oncogene protein
102884454 DUSP6; dual specificity protein phosphatase 6
102882010 TCF3; transcription factor E2-alpha isoform X1
102898077 PBX1; pre-B-cell leukemia transcription factor 1
102882050 WNT16; LOW QUALITY PROTEIN: protein Wnt-16
102884920 ETV6; transcription factor ETV6 isoform X1
102895639 ETV7; transcription factor ETV7 isoform X1
102898423 T-cell receptor beta-2 chain C region
102891942 uncharacterized protein LOC102891942
102888696 ELANE; neutrophil elastase
102881776 granzyme B(G,H)
102881520 mast cell protease 1A-like
102883711 AFF1; AF4/FMR2 family member 1 isoform X1
102880359 CDK9; cyclin-dependent kinase 9 isoform X1
102891304 CCNT1; cyclin-T1 isoform X1
102884692 CCNT2; LOW QUALITY PROTEIN: cyclin-T2
102884364 MLLT1; protein ENL isoform X1
102881660 MLLT3; protein AF-9
102893368 DOT1L; LOW QUALITY PROTEIN: histone-lysine N-methyltransferase, H3 lysine-79 specific
102893071 LMO2; LOW QUALITY PROTEIN: rhombotin-2
102897051 PBX3; pre-B-cell leukemia transcription factor 3 isoform X1
102886724 RUNX2; runt-related transcription factor 2 isoform X3
102879136 SMAD1; mothers against decapentaplegic homolog 1
102895172 KLF3; Krueppel-like factor 3 isoform X2
102883825 MEF2C; myocyte-specific enhancer factor 2C isoform X1
112479744 HOXA9; LOW QUALITY PROTEIN: homeobox protein Hox-A9
102887833 HOXA10; LOW QUALITY PROTEIN: homeobox protein Hox-A10
102878666 JMJD1C; probable JmjC domain-containing histone demethylation protein 2C isoform X1
102893619 HMGA2; high mobility group protein HMGI-C isoform X1
102897701 LOW QUALITY PROTEIN: histone demethylase UTY-like
102882574 KDM6A; LOW QUALITY PROTEIN: lysine-specific demethylase 6A
102895569 SUPT3H; transcription initiation protein SPT3 homolog
102884431 PROM1; prominin-1 isoform X1
102891572 FLT3; receptor-type tyrosine-protein kinase FLT3
102890866 BMP2K; BMP-2-inducible protein kinase
102885962 IGF1R; insulin-like growth factor 1 receptor
102880085 CDKN1B; cyclin-dependent kinase inhibitor 1B
102895895 CDK14; cyclin-dependent kinase 14 isoform X1
102896002 MEIS1; homeobox protein Meis1 isoform X1
102888082 HOXA11; LOW QUALITY PROTEIN: homeobox protein Hox-A11
102895504 SIX1; homeobox protein SIX1
102895762 SIX4; homeobox protein SIX4 isoform X1
102893048 EYA1; eyes absent homolog 1 isoform X1
102878098 CDKN2C; cyclin-dependent kinase 4 inhibitor C
102884381 HPGD; 15-hydroxyprostaglandin dehydrogenase [NAD(+)]
102892117 LOW QUALITY PROTEIN: glutamate receptor 3
102882725 FUT8; alpha-(1,6)-fucosyltransferase isoform X1
102893059 TLX3; T-cell leukemia homeobox protein 3
102893558 TLX1; T-cell leukemia homeobox protein 1
102881518 BCL11B; B-cell lymphoma/leukemia 11B
102896565 LDB1; LIM domain-binding protein 1 isoform X1
102882828 LYL1; protein lyl-1
102878210 HHEX; hematopoietically-expressed homeobox protein HHEX
102878381 PTCRA; pre T-cell antigen receptor alpha
102882961 REL; proto-oncogene c-Rel isoform X1
102892640 CCND2; G1/S-specific cyclin-D2
102884388 baculoviral IAP repeat-containing protein 3
102884651 BIRC2; baculoviral IAP repeat-containing protein 2 isoform X1
102894412 TRAF1; TNF receptor-associated factor 1
102887704 BCL2L1; bcl-2-like protein 1
102897001 CD86; T-lymphocyte activation antigen CD86
102890443 CD40; tumor necrosis factor receptor superfamily member 5 isoform X1
102888476 BCL6; B-cell lymphoma 6 protein isoform X1
102892050 immunoglobulin heavy variable 1-46
102898830 MAF; transcription factor Maf
102896485 ITGB7; integrin beta-7
102877851 NSD2; LOW QUALITY PROTEIN: histone-lysine N-methyltransferase NSD2
102898795 histone H3.1
102889188 uncharacterized protein LOC102889188
102897761 histone H3.3
102894694 histone H3.3
102892980 histone H3.1-like
102888943 histone H3.3-like
102889931 histone H3 isoform X1
112486141 histone H3-like
112481721 LOW QUALITY PROTEIN: histone H3.3
102888739 PAX5; paired box protein Pax-5 isoform X1
102894983 PAX8; paired box protein Pax-8 isoform X1
102892450 PPARG; peroxisome proliferator-activated receptor gamma isoform X1
102881572 RXRA; retinoic acid receptor RXR-alpha
102888877 RXRB; retinoic acid receptor RXR-beta isoform X1
102897820 RXRG; retinoic acid receptor RXR-gamma
102893861 PRCC; LOW QUALITY PROTEIN: proline-rich protein PRCC
102885286 TFE3; transcription factor E3 isoform X1
102894049 CDKN1A; cyclin-dependent kinase inhibitor 1
102884423 TMPRSS2; transmembrane protease serine 2
102886836 ERG; transcriptional regulator ERG isoform X1
102880095 PLAU; urokinase-type plasminogen activator
102893511 PLAT; tissue-type plasminogen activator
102886139 stromelysin-1
102889517 MMP9; matrix metalloproteinase-9
102879625 ZEB1; zinc finger E-box-binding homeobox 1
102884188 IL1R2; interleukin-1 receptor type 2
102892287 SPINT1; kunitz-type protease inhibitor 1
102887914 ETV1; ETS translocation variant 1 isoform X1
102882386 ETV4; ETS translocation variant 4 isoform X8
102882781 ETV5; ETS translocation variant 5
102892710 SLC45A3; solute carrier family 45 member 3
102892959 ELK4; ETS domain-containing protein Elk-4
102895749 DDX5; probable ATP-dependent RNA helicase DDX5
102878063 MYCN; LOW QUALITY PROTEIN: N-myc proto-oncogene protein
102881979 MAX; protein max isoform X2
102884281 MDM2; E3 ubiquitin-protein ligase Mdm2
102898998 PTK2; focal adhesion kinase 1
102889604 TP53; cellular tumor antigen p53
102883452 BMI1; polycomb complex protein BMI-1
102894100 SP1; transcription factor Sp1 isoform X1
102877831 ZBTB17; zinc finger and BTB domain-containing protein 17
112472150 NTRK1; high affinity nerve growth factor receptor
102882941 NGFR; tumor necrosis factor receptor superfamily member 16
102881190 MEN1; menin
102884203 EWSR1; RNA-binding protein EWS isoform X1
102878411 FLI1; Friend leukemia integration 1 transcription factor isoform X3
102890331 IGF1; insulin-like growth factor I isoform X3
102893403 ID2; DNA-binding protein inhibitor ID-2
102889618 TGFBR2; TGF-beta receptor type-2 isoform X1
102891216 IGFBP3; insulin-like growth factor-binding protein 3
102883706 FEV; protein FEV
102878672 ATF1; cyclic AMP-dependent transcription factor ATF-1 isoform X1
102895548 ARNT2; aryl hydrocarbon receptor nuclear translocator 2 isoform X8
102898588 ATM; serine-protein kinase ATM isoform X1
102899015 MITF; microphthalmia-associated transcription factor isoform X1
102878723 WT1; Wilms tumor protein isoform X1
102893670 PDGFA; platelet-derived growth factor subunit A
102883396 IL2RB; interleukin-2 receptor subunit beta
102889325 BAIAP3; BAI1-associated protein 3
102885686 TSPAN7; tetraspanin-7
102889060 MLF1; myeloid leukemia factor 1
102879405 NR4A3; nuclear receptor subfamily 4 group A member 3
102878617 TAF15; LOW QUALITY PROTEIN: TATA-binding protein-associated factor 2N
102888091 FUS; RNA-binding protein FUS isoform X1
102890557 DDIT3; DNA damage-inducible transcript 3 protein isoform X2
102885783 CEBPB; CCAAT/enhancer-binding protein beta
102895746 IL6; interleukin-6
102893161 NFKBIZ; NF-kappa-B inhibitor zeta isoform X2
102880692 NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1
102878395 RELA; transcription factor p65
102892534 CXCL8; interleukin-8
102892266 PAX7; paired box protein Pax-7 isoform X1
102895215 PAX3; paired box protein Pax-3 isoform X1
102892244 FOXO1; forkhead box protein O1
102891095 FLT1; vascular endothelial growth factor receptor 1 isoform X2
112469042 vascular endothelial growth factor receptor kdr-like
102894848 SS18; protein SSXT isoform X4
102891967 SS18L1; calcium-responsive transactivator isoform X1
102881950 protein SSX4-like
102895363 protein SSXA1
102889154 NUPR1; nuclear protein 1
102887917 ASPSCR1; tether containing UBX domain for GLUT4 isoform X1
102885990 MET; hepatocyte growth factor receptor isoform X1
102886440 GADD45A; growth arrest and DNA damage-inducible protein GADD45 alpha
102878191 GADD45G; growth arrest and DNA damage-inducible protein GADD45 gamma
102885790 GADD45B; growth arrest and DNA damage-inducible protein GADD45 beta
102885135 BAX; apoptosis regulator BAX isoform X1
102883540 BAK1; bcl-2 homologous antagonist/killer
102879479 DDB2; DNA damage-binding protein 2 isoform X1
102890888 POLK; DNA polymerase kappa isoform X1
|
K08367 RUNX1; runt-related transcription factor 1
K05090 CSF1R; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K10789 MPO; myeloperoxidase [EC:1.11.2.2]
K05427 CSF2; granulocyte-macrophage colony-stimulating factor
K04736 IL3; interleukin 3
K10053 RUNX1T1; CBFA2/RNUX1 translocation partner 1
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K11644 SIN3A; paired amphipathic helix protein Sin3a
K04650 NCOR1; nuclear receptor co-repressor 1
K09055 CEBPA; CCAAT/enhancer binding protein (C/EBP), alpha
K02633 PER2; period circadian protein 2
K09438 SPI1; transcription factor PU.1
K04391 CD14; monocyte differentiation antigen CD14
K06461 ITGAM; integrin alpha M
K06498 FCGR1A; high affinity immunoglobulin gamma Fc receptor I
K10056 JUP; junction plakoglobin
K10054 PML; E3 SUMO-protein ligase PML [EC:2.3.2.-]
K08527 RARA; retinoic acid receptor alpha
K06627 CCNA; cyclin-A
K06627 CCNA; cyclin-A
K10051 CEBPE; CCAAT/enhancer binding protein (C/EBP), epsilon
K02162 BCL2A1; hematopoietic Bcl-2-related protein A1
K10055 ZBTB16; zinc finger and BTB domain-containing protein 16
K04377 MYC; Myc proto-oncogene protein
K21946 DUSP6; dual specificity phosphatase 6 [EC:3.1.3.16 3.1.3.48]
K09063 TCF3; transcription factor E2-alpha
K09355 PBX1; pre-B-cell leukemia transcription factor 1
K01558 WNT16; wingless-type MMTV integration site family, member 16
K03211 ETV6_7; ETS translocation variant 6/7
K03211 ETV6_7; ETS translocation variant 6/7
K10785 TRBV; T-cell receptor beta chain V region
K10785 TRBV; T-cell receptor beta chain V region
K01327 ELANE; leukocyte elastase [EC:3.4.21.37]
K01353 GZMB; granzyme B [EC:3.4.21.79]
K01353 GZMB; granzyme B [EC:3.4.21.79]
K15184 AFF1; AF4/FMR2 family member 1
K02211 CDK9; cyclin-dependent kinase 9 [EC:2.7.11.22 2.7.11.23]
K15188 CCNT; cyclin T
K15188 CCNT; cyclin T
K15187 MLLT1_3; YEATS domain-containing protein 1/3
K15187 MLLT1_3; YEATS domain-containing protein 1/3
K11427 DOT1L; [histone H3]-lysine79 N-trimethyltransferase [EC:2.1.1.360]
K15612 LMO2; rhombotin-2
K15610 PBX3; pre-B-cell leukemia transcription factor 3
K09278 RUNX2; runt-related transcription factor 2
K04676 SMAD1; mothers against decapentaplegic homolog 1
K15605 KLF3; krueppel-like factor 3
K04454 MEF2C; MADS-box transcription enhancer factor 2C
K21950 HOXA9; homeobox protein Hox-A9
K17443 HOXA10; homrobox protein Hox-A10
K11449 JMJD1C; jumonji domain-containing protein 1C [EC:1.14.11.-]
K09283 HMGA2; high mobility group AT-hook protein 2
K11447 UTX; lysine-specific demethylase 6A [EC:1.14.11.68]
K11447 UTX; lysine-specific demethylase 6A [EC:1.14.11.68]
K11313 SUPT3H; transcription initiation protein SPT3
K06532 PROM1; prominin 1
K05092 FLT3; fms-related tyrosine kinase 3 [EC:2.7.10.1]
K08854 BMP2K; BMP2 inducible kinase [EC:2.7.11.1]
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K08821 CDK14; cyclin-dependent kinase 14 [EC:2.7.11.22]
K15613 MEIS1; homeobox protein Meis1
K21951 HOXA11; homeobox protein Hox-A11
K15614 SIX1; homeobox protein SIX1
K15615 SIX4; homeobox protein SIX4
K15616 EYA1; eyes absent homolog 1 [EC:3.1.3.48]
K06622 CDKN2C; cyclin-dependent kinase inhibitor 2C
K00069 HPGD; 15-hydroxyprostaglandin dehydrogenase (NAD) [EC:1.1.1.141]
K05199 GRIA3; glutamate receptor 3
K00717 FUT8; glycoprotein 6-alpha-L-fucosyltransferase [EC:2.4.1.68]
K15607 TLX3; T-cell leukemia homeobox protein 3
K09340 TLX1; T-cell leukemia homeobox protein 1
K22046 BCL11B; B-cell lymphoma/leukemia 11B
K15617 LDB1; LIM domain-binding protein 1
K15604 LYL1; protein lyl-1
K08024 HHEX; homeobox protein HEX
K06056 PTCRA; pre T-cell antigen receptor alpha
K09254 REL; c-Rel proto-oncogene protein
K10151 CCND2; G1/S-specific cyclin-D2
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K03172 TRAF1; TNF receptor-associated factor 1
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K05413 CD86; CD86 antigen
K03160 TNFRSF5; tumor necrosis factor receptor superfamily member 5
K15618 BCL6; B-cell lymphoma 6 protein
K06856 IGH; immunoglobulin heavy chain
K09035 CMAF; transcription factor Maf
K06590 ITGB7; integrin beta 7
K11424 WHSC1; [histone H3]-lysine36 N-dimethyltransferase NSD2 [EC:2.1.1.357]
K11253 H3; histone H3
K11253 H3; histone H3
K11253 H3; histone H3
K11253 H3; histone H3
K11253 H3; histone H3
K11253 H3; histone H3
K11253 H3; histone H3
K11253 H3; histone H3
K11253 H3; histone H3
K09383 PAX5; paired box protein 5
K09293 PAX8; paired box protein 8
K08530 NR1C3; peroxisome proliferator-activated receptor gamma
K08524 RXRA; retinoid X receptor alpha
K08525 RXRB; retinoid X receptor beta
K08526 RXRG; retinoid X receptor gamma
K13105 PRCC; proline-rich protein PRCC
K09105 TFE3; transcription factor E3
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K09633 TMPRSS2; transmembrane protease serine 2 [EC:3.4.21.122]
K09435 ERG; transcriptional regulator ERG
K01348 PLAU; urokinase plasminogen activator [EC:3.4.21.73]
K01343 PLAT; tissue plasminogen activator [EC:3.4.21.68]
K01394 MMP3; matrix metalloproteinase-3 (stromelysin 1, progelatinase) [EC:3.4.24.17]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K09299 ZEB1; zinc finger homeobox protein 1
K04387 IL1R2; interleukin 1 receptor type II
K15619 SPINT1; Kunitz-type protease inhibitor 1
K09431 ETV1; ets translocation variant 1
K15592 ETV4; ets translocation variant 4
K15593 ETV5; ets translocation variant 5
K15379 SLC45A3; solute carrier family 45, member 3
K04376 ELK4; ETS domain-containing protein Elk-4
K12823 DDX5; ATP-dependent RNA helicase DDX5/DBP2 [EC:5.6.2.7]
K09109 NMYC; N-myc proto-oncogene protein
K04453 MAX; Max protein
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
K04451 TP53; tumor protein p53
K11459 PCGF4; polycomb group RING finger protein 4
K04684 SP1; transcription factor Sp1
K10500 ZBTB17; zinc finger and BTB domain-containing protein 17
K03176 NTRK1; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K02583 NGFR; tumor necrosis factor receptor superfamily member 16
K14970 MEN1; menin
K13209 EWSR1; RNA-binding protein EWS
K09436 FLI1; friend leukemia integration 1 transcription factor
K05459 IGF1; insulin-like growth factor 1
K17693 ID2; DNA-binding protein inhibitor ID2
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K10138 IGFBP3; insulin-like growth factor-binding protein 3
K09437 FEV; ETS oncogene family protein FEV
K09053 ATF1; activating transcription factor 1
K15589 ARNT2; aryl hydrocarbon receptor nuclear translocator 2
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K09455 MITF; microphthalmia-associated transcription factor
K09234 WT1; Wilms tumor protein 1
K04359 PDGFA; platelet-derived growth factor subunit A
K05069 IL2RB; interleukin 2 receptor beta
K15621 BAIAP3; BAI1-associated protein 3
K06571 TSPAN7; tetraspanin-7
K15622 MLF1; myeloid leukemia factor 1
K08559 NR4A3; nuclear receptor subfamily 4 group A member 3
K14651 TAF15; transcription initiation factor TFIID subunit 15
K13098 TLS; RNA-binding protein FUS
K04452 DDIT3; DNA damage-inducible transcript 3
K10048 CEBPB; CCAAT/enhancer binding protein (C/EBP), beta
K05405 IL6; interleukin 6
K14242 NFKBIZ; NF-kappa-B inhibitor zeta
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K10030 IL8; interleukin 8
K09381 PAX3_7; paired box protein 3/7
K09381 PAX3_7; paired box protein 3/7
K07201 FOXO1; forkhead box protein O1
K05096 FLT1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
K05096 FLT1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
K15623 SS18; protein SSXT
K15623 SS18; protein SSXT
K15624 SSX1; protein SSX1
K15624 SSX1; protein SSX1
K15626 NUPR1; nuclear protein 1
K15627 ASPSCR1; tether containing UBX domain for GLUT4
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
|
05206 MicroRNAs in cancer [PATH:pale05206]
|
05205 Proteoglycans in cancer [PATH:pale05205]
|
05204 Chemical carcinogenesis - DNA adducts [PATH:pale05204]
|
05207 Chemical carcinogenesis - receptor activation [PATH:pale05207]
|
05208 Chemical carcinogenesis - reactive oxygen species [PATH:pale05208]
|
05203 Viral carcinogenesis [PATH:pale05203]
|
05230 Central carbon metabolism in cancer [PATH:pale05230]
|
05231 Choline metabolism in cancer [PATH:pale05231]
|
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer [PATH:pale05235]
|
|
|
09162 Cancer: specific types
|
05210 Colorectal cancer [PATH:pale05210]
|
102882441 GSK3B; glycogen synthase kinase-3 beta isoform X4
102878657 AXIN1; axin-1 isoform X1
102885831 AXIN2; axin-2
102880017 CTNNB1; LOW QUALITY PROTEIN: catenin beta-1
102880260 APC; adenomatous polyposis coli protein isoform X3
102891886 APC2; adenomatous polyposis coli protein 2
102885788 TCF7; transcription factor 7 isoform X4
102886093 TCF7L1; transcription factor 7-like 1
102880370 TCF7L2; transcription factor 7-like 2 isoform X2
102886933 LEF1; lymphoid enhancer-binding factor 1 isoform X1
102888083 BIRC5; baculoviral IAP repeat-containing protein 5
102895524 MYC; myc proto-oncogene protein
102885330 CCND1; G1/S-specific cyclin-D1
102895590 KRAS; GTPase KRas isoform X1
102889227 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
102880320 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
102889576 PIK3CD; LOW QUALITY PROTEIN: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
102879163 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1
102891637 phosphatidylinositol 3-kinase regulatory subunit gamma isoform X3
102879453 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
102885144 AKT1; RAC-alpha serine/threonine-protein kinase isoform X1
102879337 AKT3; RAC-gamma serine/threonine-protein kinase isoform X1
102898305 AKT2; LOW QUALITY PROTEIN: RAC-beta serine/threonine-protein kinase
102877892 BAD; bcl2-associated agonist of cell death isoform X1
102878565 CASP9; caspase-9
102877877 ARAF; serine/threonine-protein kinase A-Raf isoform X2
102878393 BRAF; serine/threonine-protein kinase B-raf isoform X2
102893439 RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X1
102897122 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 isoform X1
102879034 MAP2K2; dual specificity mitogen-activated protein kinase kinase 2
102895390 MAPK1; mitogen-activated protein kinase 1
102885749 MAPK3; mitogen-activated protein kinase 3
102896121 JUN; transcription factor AP-1
102891428 FOS; proto-oncogene c-Fos
102880177 RALGDS; ral guanine nucleotide dissociation stimulator isoform X2
102898811 RALA; ras-related protein Ral-A
102899030 RALB; ras-related protein Ral-B
102897644 RAC1; ras-related C3 botulinum toxin substrate 1 isoform X1
102885507 RAC2; ras-related C3 botulinum toxin substrate 2
102887421 RAC3; ras-related C3 botulinum toxin substrate 3
102891515 RHOA; transforming protein RhoA
102885064 MAPK10; mitogen-activated protein kinase 10 isoform X5
102890689 MAPK9; mitogen-activated protein kinase 9 isoform X1
102892777 MAPK8; mitogen-activated protein kinase 8 isoform X1
102886027 DCC; netrin receptor DCC
102897289 CASP3; caspase-3
102887604 APPL1; DCC-interacting protein 13-alpha
102884154 TGFB1; transforming growth factor beta-1
102881295 TGFB2; transforming growth factor beta-2 isoform X2
102893304 TGFB3; transforming growth factor beta-3
102880759 TGFBR1; TGF-beta receptor type-1 isoform X2
102889618 TGFBR2; TGF-beta receptor type-2 isoform X1
102893928 SMAD2; mothers against decapentaplegic homolog 2
102895268 SMAD3; mothers against decapentaplegic homolog 3
102886521 SMAD4; mothers against decapentaplegic homolog 4
102898392 MLH1; DNA mismatch repair protein Mlh1 isoform X1
102893728 MSH2; DNA mismatch repair protein Msh2 isoform X3
102878992 MSH3; DNA mismatch repair protein Msh3 isoform X1
102892999 MSH6; DNA mismatch repair protein Msh6
102885135 BAX; apoptosis regulator BAX isoform X1
102894490 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
102890309 BCL2L11; bcl-2-like protein 11 isoform X1
102892591 BBC3; bcl-2-binding component 3
102896443 BCL2; apoptosis regulator Bcl-2
102879159 cytochrome c
102893036 cytochrome c, testis-specific-like
102889604 TP53; cellular tumor antigen p53
102894049 CDKN1A; cyclin-dependent kinase inhibitor 1
102886440 GADD45A; growth arrest and DNA damage-inducible protein GADD45 alpha
102878191 GADD45G; growth arrest and DNA damage-inducible protein GADD45 gamma
102885790 GADD45B; growth arrest and DNA damage-inducible protein GADD45 beta
102883540 BAK1; bcl-2 homologous antagonist/killer
102879479 DDB2; DNA damage-binding protein 2 isoform X1
102890888 POLK; DNA polymerase kappa isoform X1
102891552 EGF; pro-epidermal growth factor isoform X1
102887662 TGFA; protransforming growth factor alpha isoform X1
102884726 EREG; proepiregulin
102884477 AREG; amphiregulin
102893495 EGFR; epidermal growth factor receptor
102878822 GRB2; growth factor receptor-bound protein 2 isoform X1
102882462 SOS1; son of sevenless homolog 1 isoform X1
102889597 SOS2; son of sevenless homolog 2
102896270 HRAS; GTPase HRas isoform X3
102885950 NRAS; GTPase NRas isoform X2
102885092 MTOR; serine/threonine-protein kinase mTOR
102891214 RPS6KB2; ribosomal protein S6 kinase beta-2 isoform X1
102889369 RPS6KB1; ribosomal protein S6 kinase beta-1 isoform X1
|
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02105 CTNNB1; catenin beta 1
K02085 APC; adenomatosis polyposis coli protein
K02085 APC; adenomatosis polyposis coli protein
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K08731 BIRC5; baculoviral IAP repeat-containing protein 5
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; G1/S-specific cyclin-D1
K07827 KRAS; GTPase KRas
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04379 FOS; proto-oncogene protein c-fos
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K07834 RALA; Ras-related protein Ral-A
K07835 RALB; Ras-related protein Ral-B
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04513 RHOA; Ras homolog gene family, member A
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K06765 DCC; deleted in colorectal carcinoma
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K08733 APPL1; DCC-interacting protein 13 alpha
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K08734 MLH1; DNA mismatch repair protein MLH1
K08735 MSH2; DNA mismatch repair protein MSH2
K08736 MSH3; DNA mismatch repair protein MSH3
K08737 MSH6; DNA mismatch repair protein MSH6
K02159 BAX; apoptosis regulator BAX
K10131 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
K16341 BCL2L11; Bcl-2-like protein 11
K10132 BBC3; Bcl-2-binding component 3
K02161 BCL2; apoptosis regulator Bcl-2
K08738 CYC; cytochrome c
K08738 CYC; cytochrome c
K04451 TP53; tumor protein p53
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K14021 BAK; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K09784 EREG; epiregulin
K09782 AREG; amphiregulin
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07828 NRAS; GTPase NRas
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
|
05212 Pancreatic cancer [PATH:pale05212]
|
102895590 KRAS; GTPase KRas isoform X1
102889227 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
102880320 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
102889576 PIK3CD; LOW QUALITY PROTEIN: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
102879163 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1
102891637 phosphatidylinositol 3-kinase regulatory subunit gamma isoform X3
102879453 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
102885217 ARHGEF6; rho guanine nucleotide exchange factor 6
102897644 RAC1; ras-related C3 botulinum toxin substrate 1 isoform X1
102885507 RAC2; ras-related C3 botulinum toxin substrate 2
102887421 RAC3; ras-related C3 botulinum toxin substrate 3
102880692 NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1
102878395 RELA; transcription factor p65
102885144 AKT1; RAC-alpha serine/threonine-protein kinase isoform X1
102879337 AKT3; RAC-gamma serine/threonine-protein kinase isoform X1
102898305 AKT2; LOW QUALITY PROTEIN: RAC-beta serine/threonine-protein kinase
102879469 CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
102893261 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1
102880203 IKBKG; NF-kappa-B essential modulator isoform X1
102877892 BAD; bcl2-associated agonist of cell death isoform X1
102887704 BCL2L1; bcl-2-like protein 1
102878565 CASP9; caspase-9
102877877 ARAF; serine/threonine-protein kinase A-Raf isoform X2
102878393 BRAF; serine/threonine-protein kinase B-raf isoform X2
102893439 RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X1
102897122 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 isoform X1
102895390 MAPK1; mitogen-activated protein kinase 1
102885749 MAPK3; mitogen-activated protein kinase 3
102885064 MAPK10; mitogen-activated protein kinase 10 isoform X5
102890689 MAPK9; mitogen-activated protein kinase 9 isoform X1
102892777 MAPK8; mitogen-activated protein kinase 8 isoform X1
102880177 RALGDS; ral guanine nucleotide dissociation stimulator isoform X2
102898811 RALA; ras-related protein Ral-A
102899030 RALB; ras-related protein Ral-B
102890515 RALBP1; ralA-binding protein 1 isoform X1
102889114 CDC42; cell division control protein 42 homolog
102884736 PLD1; phospholipase D1 isoform X1
102894598 PLD2; phospholipase D2 isoform X1
102887662 TGFA; protransforming growth factor alpha isoform X1
102891552 EGF; pro-epidermal growth factor isoform X1
102893495 EGFR; epidermal growth factor receptor
102885300 ERBB2; LOW QUALITY PROTEIN: receptor tyrosine-protein kinase erbB-2
102885092 MTOR; serine/threonine-protein kinase mTOR
102891214 RPS6KB2; ribosomal protein S6 kinase beta-2 isoform X1
102889369 RPS6KB1; ribosomal protein S6 kinase beta-1 isoform X1
102880365 JAK1; tyrosine-protein kinase JAK1 isoform X1
102884374 STAT3; LOW QUALITY PROTEIN: signal transducer and activator of transcription 3
102886603 STAT1; signal transducer and activator of transcription 1-alpha/beta
102890394 VEGFA; vascular endothelial growth factor A isoform X2
102896422 LOW QUALITY PROTEIN: cyclin-dependent kinase inhibitor 2A
102894222 CDK4; cyclin-dependent kinase 4
102896272 CDK6; cyclin-dependent kinase 6
102885330 CCND1; G1/S-specific cyclin-D1
102893019 RB1; retinoblastoma-associated protein
102895276 E2F1; transcription factor E2F1
102884459 E2F2; transcription factor E2F2 isoform X1
102887239 E2F3; transcription factor E2F3 isoform X1
102889604 TP53; cellular tumor antigen p53
102894049 CDKN1A; cyclin-dependent kinase inhibitor 1
102886440 GADD45A; growth arrest and DNA damage-inducible protein GADD45 alpha
102878191 GADD45G; growth arrest and DNA damage-inducible protein GADD45 gamma
102885790 GADD45B; growth arrest and DNA damage-inducible protein GADD45 beta
102885135 BAX; apoptosis regulator BAX isoform X1
102883540 BAK1; bcl-2 homologous antagonist/killer
102879479 DDB2; DNA damage-binding protein 2 isoform X1
102890888 POLK; DNA polymerase kappa isoform X1
102884154 TGFB1; transforming growth factor beta-1
102881295 TGFB2; transforming growth factor beta-2 isoform X2
102893304 TGFB3; transforming growth factor beta-3
102880759 TGFBR1; TGF-beta receptor type-1 isoform X2
102889618 TGFBR2; TGF-beta receptor type-2 isoform X1
102893928 SMAD2; mothers against decapentaplegic homolog 2
102895268 SMAD3; mothers against decapentaplegic homolog 3
102886521 SMAD4; mothers against decapentaplegic homolog 4
102896802 BRCA2; breast cancer type 2 susceptibility protein
102894016 RAD51; DNA repair protein RAD51 homolog 1
|
K07827 KRAS; GTPase KRas
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K05729 ARHGEF6; Rho guanine nucleotide exchange factor 6
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K02158 BAD; Bcl-2-antagonist of cell death
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K07834 RALA; Ras-related protein Ral-A
K07835 RALB; Ras-related protein Ral-B
K08773 RALBP1; RalA-binding protein 1
K04393 CDC42; cell division control protein 42
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K08774 TGFA; transforming growth factor, alpha
K04357 EGF; epidermal growth factor
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K11220 STAT1; signal transducer and activator of transcription 1
K05448 VEGFA; vascular endothelial growth factor A
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K04503 CCND1; G1/S-specific cyclin-D1
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04451 TP53; tumor protein p53
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K08775 BRCA2; breast cancer 2 susceptibility protein
K04482 RAD51; DNA repair protein RAD51
|
05225 Hepatocellular carcinoma [PATH:pale05225]
|
102887662 TGFA; protransforming growth factor alpha isoform X1
102893495 EGFR; epidermal growth factor receptor
102880410 IGF2; insulin-like growth factor II
102885962 IGF1R; insulin-like growth factor 1 receptor
102896228 PLCG1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1
102883128 PLCG2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
102887078 PRKCA; protein kinase C alpha type
102880663 PRKCB; protein kinase C beta type
102888961 PRKCG; protein kinase C gamma type
102878877 ELK1; ETS domain-containing protein Elk-1 isoform X1
102894443 SHC1; LOW QUALITY PROTEIN: SHC-transforming protein 1
102885958 SHC2; SHC-transforming protein 2
102879956 SHC3; SHC-transforming protein 3
102888926 SHC4; SHC-transforming protein 4
102878822 GRB2; growth factor receptor-bound protein 2 isoform X1
102882462 SOS1; son of sevenless homolog 1 isoform X1
102889597 SOS2; son of sevenless homolog 2
102896270 HRAS; GTPase HRas isoform X3
102895590 KRAS; GTPase KRas isoform X1
102885950 NRAS; GTPase NRas isoform X2
102877877 ARAF; serine/threonine-protein kinase A-Raf isoform X2
102878393 BRAF; serine/threonine-protein kinase B-raf isoform X2
102893439 RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X1
102897122 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 isoform X1
102879034 MAP2K2; dual specificity mitogen-activated protein kinase kinase 2
102895390 MAPK1; mitogen-activated protein kinase 1
102885749 MAPK3; mitogen-activated protein kinase 3
102889227 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
102880320 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
102889576 PIK3CD; LOW QUALITY PROTEIN: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
102879163 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1
102891637 phosphatidylinositol 3-kinase regulatory subunit gamma isoform X3
102879453 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
102881949 PTEN; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X1
102885144 AKT1; RAC-alpha serine/threonine-protein kinase isoform X1
102879337 AKT3; RAC-gamma serine/threonine-protein kinase isoform X1
102898305 AKT2; LOW QUALITY PROTEIN: RAC-beta serine/threonine-protein kinase
102885092 MTOR; serine/threonine-protein kinase mTOR
102891214 RPS6KB2; ribosomal protein S6 kinase beta-2 isoform X1
102889369 RPS6KB1; ribosomal protein S6 kinase beta-1 isoform X1
102877892 BAD; bcl2-associated agonist of cell death isoform X1
102887704 BCL2L1; bcl-2-like protein 1
102895524 MYC; myc proto-oncogene protein
102893019 RB1; retinoblastoma-associated protein
102895276 E2F1; transcription factor E2F1
102884459 E2F2; transcription factor E2F2 isoform X1
102887239 E2F3; transcription factor E2F3 isoform X1
102895256 TERT; telomerase reverse transcriptase
102889604 TP53; cellular tumor antigen p53
102894049 CDKN1A; cyclin-dependent kinase inhibitor 1
102886440 GADD45A; growth arrest and DNA damage-inducible protein GADD45 alpha
102878191 GADD45G; growth arrest and DNA damage-inducible protein GADD45 gamma
102885790 GADD45B; growth arrest and DNA damage-inducible protein GADD45 beta
102885135 BAX; apoptosis regulator BAX isoform X1
102883540 BAK1; bcl-2 homologous antagonist/killer
102879479 DDB2; DNA damage-binding protein 2 isoform X1
102890888 POLK; DNA polymerase kappa isoform X1
102896422 LOW QUALITY PROTEIN: cyclin-dependent kinase inhibitor 2A
102894222 CDK4; cyclin-dependent kinase 4
102896272 CDK6; cyclin-dependent kinase 6
102885330 CCND1; G1/S-specific cyclin-D1
102884154 TGFB1; transforming growth factor beta-1
102881295 TGFB2; transforming growth factor beta-2 isoform X2
102893304 TGFB3; transforming growth factor beta-3
102880759 TGFBR1; TGF-beta receptor type-1 isoform X2
102889618 TGFBR2; TGF-beta receptor type-2 isoform X1
102893928 SMAD2; mothers against decapentaplegic homolog 2
102895268 SMAD3; mothers against decapentaplegic homolog 3
102886521 SMAD4; mothers against decapentaplegic homolog 4
102888016 WNT1; proto-oncogene Wnt-1
102880959 WNT2B; protein Wnt-2b isoform X1
102885080 WNT2; protein Wnt-2
102895795 WNT3A; protein Wnt-3a
102877979 WNT3; proto-oncogene Wnt-3
102888866 WNT4; protein Wnt-4
102890342 WNT5A; protein Wnt-5a isoform X5
102881682 WNT5B; protein Wnt-5b isoform X2
102882368 WNT6; protein Wnt-6 isoform X1
102888597 WNT7A; protein Wnt-7a
102898026 WNT7B; protein Wnt-7b isoform X1
102896480 WNT8A; protein Wnt-8a
102878209 WNT8B; protein Wnt-8b
102885223 protein Wnt-9b
102884543 WNT9A; protein Wnt-9a
102882121 WNT10A; protein Wnt-10a
102888263 WNT10B; protein Wnt-10b
102877879 WNT11; protein Wnt-11
102882050 WNT16; LOW QUALITY PROTEIN: protein Wnt-16
102880538 FZD7; frizzled-7
102895634 FZD1; frizzled-1
102884150 FZD2; frizzled-2
102890038 FZD3; frizzled-3 isoform X1
102892989 FZD4; LOW QUALITY PROTEIN: frizzled-4
102877864 FZD8; LOW QUALITY PROTEIN: frizzled-8
102883426 FZD5; LOW QUALITY PROTEIN: frizzled-5
102890002 FZD6; frizzled-6
102894135 FZD10; frizzled-10
102878169 FZD9; frizzled-9
102894479 LRP5; low-density lipoprotein receptor-related protein 5
102878233 LRP6; low-density lipoprotein receptor-related protein 6
102895469 DVL3; segment polarity protein dishevelled homolog DVL-3 isoform X1
102880039 DVL2; segment polarity protein dishevelled homolog DVL-2 isoform X1
102881158 DVL1; segment polarity protein dishevelled homolog DVL-1 isoform X1
102896339 LOW QUALITY PROTEIN: proto-oncogene FRAT1
102882441 GSK3B; glycogen synthase kinase-3 beta isoform X4
102878657 AXIN1; axin-1 isoform X1
102885831 AXIN2; axin-2
102880260 APC; adenomatous polyposis coli protein isoform X3
102891886 APC2; adenomatous polyposis coli protein 2
102880017 CTNNB1; LOW QUALITY PROTEIN: catenin beta-1
102884974 CSNK1A1; casein kinase I isoform X3
102885788 TCF7; transcription factor 7 isoform X4
102886093 TCF7L1; transcription factor 7-like 1
102880370 TCF7L2; transcription factor 7-like 2 isoform X2
102886933 LEF1; lymphoid enhancer-binding factor 1 isoform X1
102894870 KEAP1; kelch-like ECH-associated protein 1
102892042 NFE2L2; nuclear factor erythroid 2-related factor 2 isoform X1
102880347 HMOX1; LOW QUALITY PROTEIN: heme oxygenase 1
102889138 NQO1; NAD(P)H dehydrogenase [quinone] 1
102885225 MGST2; microsomal glutathione S-transferase 2
102886852 GSTO2; glutathione S-transferase omega-2
102887110 GSTO1; glutathione S-transferase omega-1
102887332 MGST1; microsomal glutathione S-transferase 1
102891202 MGST3; microsomal glutathione S-transferase 3
102891351 GSTA4; glutathione S-transferase A4
102897012 glutathione S-transferase A3-like
102883042 glutathione S-transferase theta-1
102883292 glutathione S-transferase theta-3
102893685 GSTM4; glutathione S-transferase Mu 4 isoform X3
102894088 glutathione S-transferase Mu 5
102891589 glutathione S-transferase A4
107195441 glutathione S-transferase theta-1
102882795 glutathione S-transferase theta-4
102889068 glutathione S-transferase P isoform X2
102896271 glutathione S-transferase P
102887506 TXNRD1; thioredoxin reductase 1, cytoplasmic
102894141 TXNRD3; thioredoxin reductase 3
102890334 TXNRD2; thioredoxin reductase 2, mitochondrial isoform X2
102884470 HGF; hepatocyte growth factor isoform X1
102885990 MET; hepatocyte growth factor receptor isoform X1
102881252 GAB1; GRB2-associated-binding protein 1 isoform X6
102884158 ACTG1; actin, cytoplasmic 2
102884469 ACTB; actin, cytoplasmic 1
102896269 actin-like protein 6A
102896523 actin-like protein 6A
102883939 ACTL6B; actin-like protein 6B
102898178 SMARCD2; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2
102889848 SMARCD3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 isoform X1
102881039 SMARCD1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1
102881131 PHF10; PHD finger protein 10 isoform X1
102888819 DPF1; zinc finger protein neuro-d4 isoform X2
102882191 DPF3; zinc finger protein DPF3
102890374 ARID1A; AT-rich interactive domain-containing protein 1A isoform X1
102885261 ARID1B; AT-rich interactive domain-containing protein 1B isoform X1
102878867 SMARCE1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 isoform X3
102881630 SMARCB1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 isoform X1
102898574 SMARCC2; SWI/SNF complex subunit SMARCC2
102894909 SMARCC1; SWI/SNF complex subunit SMARCC1
102889041 SMARCA4; transcription activator BRG1 isoform X2
102878751 ARID2; AT-rich interactive domain-containing protein 2 isoform X1
102895944 PBRM1; LOW QUALITY PROTEIN: protein polybromo-1
102881366 BRD7; bromodomain-containing protein 7
|
K08774 TGFA; transforming growth factor, alpha
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K13769 IGF2; insulin-like growth factor 2
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04375 ELK1; ETS domain-containing protein Elk-1
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K04377 MYC; Myc proto-oncogene protein
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]
K04451 TP53; tumor protein p53
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K04503 CCND1; G1/S-specific cyclin-D1
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7; frizzled 1/7
K02432 FZD1_7; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4; frizzled 4
K02375 FZD5_8; frizzled 5/8
K02375 FZD5_8; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10; frizzled 9/10
K02842 FZD9_10; frizzled 9/10
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K03069 FRAT1; frequently rearranged in advanced T-cell lymphomas 1
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02085 APC; adenomatosis polyposis coli protein
K02085 APC; adenomatosis polyposis coli protein
K02105 CTNNB1; catenin beta 1
K08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K10456 KLHL19; kelch-like protein 19
K05638 NFE2L2; nuclear factor erythroid 2-related factor 2
K00510 HMOX1; heme oxygenase 1 [EC:1.14.14.18]
K00355 NQO1; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K23790 GSTP; glutathione S-transferase P [EC:2.5.1.18]
K23790 GSTP; glutathione S-transferase P [EC:2.5.1.18]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K05460 HGF; hepatocyte growth factor
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K09593 GAB1; GRB2-associated-binding protein 1
K05692 ACTB_G1; actin beta/gamma 1
K05692 ACTB_G1; actin beta/gamma 1
K11340 ACTL6A; actin-like protein 6A
K11340 ACTL6A; actin-like protein 6A
K11652 ACTL6B; actin-like protein 6B
K11650 SMARCD; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D
K11650 SMARCD; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D
K11650 SMARCD; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D
K22197 BAF45A; BRG1-associated factor 45A
K22198 BAF45B_C; BRG1-associated factor 45B/C
K22198 BAF45B_C; BRG1-associated factor 45B/C
K11653 ARID1; AT-rich interactive domain-containing protein 1
K11653 ARID1; AT-rich interactive domain-containing protein 1
K11651 SMARCE1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1
K11648 SMARCB1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1
K11649 SMARCC; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C
K11649 SMARCC; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C
K11647 SMARCA2_4; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2/4 [EC:5.6.2.-]
K11765 ARID2; AT-rich interactive domain-containing protein 2
K11757 PBRM1; protein polybromo-1
K11723 BRD7; bromodomain-containing protein 7
|
05226 Gastric cancer [PATH:pale05226]
|
102882303 MUC2; mucin-2
102891269 CDH17; cadherin-17
102892377 REG4; regenerating islet-derived protein 4 isoform X1
102879811 ABCB1; multidrug resistance protein 1 isoform X1
102882514 SHH; sonic hedgehog protein
102889604 TP53; cellular tumor antigen p53
102894049 CDKN1A; cyclin-dependent kinase inhibitor 1
102886440 GADD45A; growth arrest and DNA damage-inducible protein GADD45 alpha
102878191 GADD45G; growth arrest and DNA damage-inducible protein GADD45 gamma
102885790 GADD45B; growth arrest and DNA damage-inducible protein GADD45 beta
102885135 BAX; apoptosis regulator BAX isoform X1
102883540 BAK1; bcl-2 homologous antagonist/killer
102879479 DDB2; DNA damage-binding protein 2 isoform X1
102890888 POLK; DNA polymerase kappa isoform X1
102886545 RARB; retinoic acid receptor beta
102881572 RXRA; retinoic acid receptor RXR-alpha
102888877 RXRB; retinoic acid receptor RXR-beta isoform X1
102897820 RXRG; retinoic acid receptor RXR-gamma
102888016 WNT1; proto-oncogene Wnt-1
102880959 WNT2B; protein Wnt-2b isoform X1
102885080 WNT2; protein Wnt-2
102895795 WNT3A; protein Wnt-3a
102877979 WNT3; proto-oncogene Wnt-3
102888866 WNT4; protein Wnt-4
102890342 WNT5A; protein Wnt-5a isoform X5
102881682 WNT5B; protein Wnt-5b isoform X2
102882368 WNT6; protein Wnt-6 isoform X1
102888597 WNT7A; protein Wnt-7a
102898026 WNT7B; protein Wnt-7b isoform X1
102896480 WNT8A; protein Wnt-8a
102878209 WNT8B; protein Wnt-8b
102885223 protein Wnt-9b
102884543 WNT9A; protein Wnt-9a
102882121 WNT10A; protein Wnt-10a
102888263 WNT10B; protein Wnt-10b
102877879 WNT11; protein Wnt-11
102882050 WNT16; LOW QUALITY PROTEIN: protein Wnt-16
102880538 FZD7; frizzled-7
102895634 FZD1; frizzled-1
102884150 FZD2; frizzled-2
102890038 FZD3; frizzled-3 isoform X1
102892989 FZD4; LOW QUALITY PROTEIN: frizzled-4
102877864 FZD8; LOW QUALITY PROTEIN: frizzled-8
102883426 FZD5; LOW QUALITY PROTEIN: frizzled-5
102890002 FZD6; frizzled-6
102894135 FZD10; frizzled-10
102878169 FZD9; frizzled-9
102894479 LRP5; low-density lipoprotein receptor-related protein 5
102878233 LRP6; low-density lipoprotein receptor-related protein 6
102895469 DVL3; segment polarity protein dishevelled homolog DVL-3 isoform X1
102880039 DVL2; segment polarity protein dishevelled homolog DVL-2 isoform X1
102881158 DVL1; segment polarity protein dishevelled homolog DVL-1 isoform X1
102896339 LOW QUALITY PROTEIN: proto-oncogene FRAT1
102882441 GSK3B; glycogen synthase kinase-3 beta isoform X4
102878657 AXIN1; axin-1 isoform X1
102885831 AXIN2; axin-2
102880260 APC; adenomatous polyposis coli protein isoform X3
102891886 APC2; adenomatous polyposis coli protein 2
102880017 CTNNB1; LOW QUALITY PROTEIN: catenin beta-1
102884974 CSNK1A1; casein kinase I isoform X3
102885788 TCF7; transcription factor 7 isoform X4
102886093 TCF7L1; transcription factor 7-like 1
102880370 TCF7L2; transcription factor 7-like 2 isoform X2
102886933 LEF1; lymphoid enhancer-binding factor 1 isoform X1
102895524 MYC; myc proto-oncogene protein
102885330 CCND1; G1/S-specific cyclin-D1
102895256 TERT; telomerase reverse transcriptase
102891552 EGF; pro-epidermal growth factor isoform X1
102893495 EGFR; epidermal growth factor receptor
102885300 ERBB2; LOW QUALITY PROTEIN: receptor tyrosine-protein kinase erbB-2
102894443 SHC1; LOW QUALITY PROTEIN: SHC-transforming protein 1
102885958 SHC2; SHC-transforming protein 2
102879956 SHC3; SHC-transforming protein 3
102888926 SHC4; SHC-transforming protein 4
102878822 GRB2; growth factor receptor-bound protein 2 isoform X1
102882462 SOS1; son of sevenless homolog 1 isoform X1
102889597 SOS2; son of sevenless homolog 2
102896270 HRAS; GTPase HRas isoform X3
102895590 KRAS; GTPase KRas isoform X1
102885950 NRAS; GTPase NRas isoform X2
102877877 ARAF; serine/threonine-protein kinase A-Raf isoform X2
102878393 BRAF; serine/threonine-protein kinase B-raf isoform X2
102893439 RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X1
102897122 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 isoform X1
102879034 MAP2K2; dual specificity mitogen-activated protein kinase kinase 2
102895390 MAPK1; mitogen-activated protein kinase 1
102885749 MAPK3; mitogen-activated protein kinase 3
102889227 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
102880320 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
102889576 PIK3CD; LOW QUALITY PROTEIN: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
102879163 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1
102891637 phosphatidylinositol 3-kinase regulatory subunit gamma isoform X3
102879453 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
102885144 AKT1; RAC-alpha serine/threonine-protein kinase isoform X1
102879337 AKT3; RAC-gamma serine/threonine-protein kinase isoform X1
102898305 AKT2; LOW QUALITY PROTEIN: RAC-beta serine/threonine-protein kinase
102885092 MTOR; serine/threonine-protein kinase mTOR
102891214 RPS6KB2; ribosomal protein S6 kinase beta-2 isoform X1
102889369 RPS6KB1; ribosomal protein S6 kinase beta-1 isoform X1
102896443 BCL2; apoptosis regulator Bcl-2
102898392 MLH1; DNA mismatch repair protein Mlh1 isoform X1
102880085 CDKN1B; cyclin-dependent kinase inhibitor 1B
102893397 CDK2; cyclin-dependent kinase 2 isoform X1
102882411 CCNE2; G1/S-specific cyclin-E2 isoform X1
102882260 CCNE1; LOW QUALITY PROTEIN: G1/S-specific cyclin-E1
102893019 RB1; retinoblastoma-associated protein
102895276 E2F1; transcription factor E2F1
102884459 E2F2; transcription factor E2F2 isoform X1
102887239 E2F3; transcription factor E2F3 isoform X1
102884154 TGFB1; transforming growth factor beta-1
102881295 TGFB2; transforming growth factor beta-2 isoform X2
102893304 TGFB3; transforming growth factor beta-3
102880759 TGFBR1; TGF-beta receptor type-1 isoform X2
102889618 TGFBR2; TGF-beta receptor type-2 isoform X1
102893928 SMAD2; mothers against decapentaplegic homolog 2
102895268 SMAD3; mothers against decapentaplegic homolog 3
102886521 SMAD4; mothers against decapentaplegic homolog 4
102893142 CDKN2B; cyclin-dependent kinase 4 inhibitor B
102886394 CDH1; cadherin-1 isoform X1
102893948 CTNNA2; catenin alpha-2 isoform X3
102881133 CTNNA3; catenin alpha-3
102891804 CTNNA1; catenin alpha-1
102890702 JUP; junction plakoglobin isoform X2
102884470 HGF; hepatocyte growth factor isoform X1
102885990 MET; hepatocyte growth factor receptor isoform X1
102894192 FGF1; fibroblast growth factor 1 isoform X1
107196088 FGF2; fibroblast growth factor 2
102895922 FGF10; fibroblast growth factor 10
102887777 FGF7; fibroblast growth factor 7
102892141 FGF6; fibroblast growth factor 6
102895642 FGF5; fibroblast growth factor 5
102890153 FGF16; fibroblast growth factor 16
102893226 FGF8; fibroblast growth factor 8 isoform X4
102894115 FGF18; fibroblast growth factor 18
102888098 FGF20; fibroblast growth factor 20
102893244 FGF4; fibroblast growth factor 4
102894279 FGF17; fibroblast growth factor 17 isoform X1
102887882 FGF9; fibroblast growth factor 9
102896895 FGF22; fibroblast growth factor 22
102885081 FGF19; fibroblast growth factor 19
102886540 FGF21; fibroblast growth factor 21
102883346 FGF23; fibroblast growth factor 23
102882899 FGFR2; fibroblast growth factor receptor 2 isoform X8
102881252 GAB1; GRB2-associated-binding protein 1 isoform X6
|
K10955 MUC2; mucin-2
K06811 CDH17; cadherin 17, LI cadherin
K22244 REG4; regenerating islet-derived protein 4
K05658 ABCB1; ATP-binding cassette, subfamily B (MDR/TAP), member 1 [EC:7.6.2.2]
K11988 SHH; sonic hedgehog
K04451 TP53; tumor protein p53
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K08528 RARB; retinoic acid receptor beta
K08524 RXRA; retinoid X receptor alpha
K08525 RXRB; retinoid X receptor beta
K08526 RXRG; retinoid X receptor gamma
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7; frizzled 1/7
K02432 FZD1_7; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4; frizzled 4
K02375 FZD5_8; frizzled 5/8
K02375 FZD5_8; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10; frizzled 9/10
K02842 FZD9_10; frizzled 9/10
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K03069 FRAT1; frequently rearranged in advanced T-cell lymphomas 1
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02085 APC; adenomatosis polyposis coli protein
K02085 APC; adenomatosis polyposis coli protein
K02105 CTNNB1; catenin beta 1
K08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; G1/S-specific cyclin-D1
K11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]
K04357 EGF; epidermal growth factor
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K02161 BCL2; apoptosis regulator Bcl-2
K08734 MLH1; DNA mismatch repair protein MLH1
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04685 CDKN2B; cyclin-dependent kinase inhibitor 2B
K05689 CDH1; cadherin 1, type 1, E-cadherin
K05691 CTNNA; catenin alpha
K05691 CTNNA; catenin alpha
K05691 CTNNA; catenin alpha
K10056 JUP; junction plakoglobin
K05460 HGF; hepatocyte growth factor
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K05093 FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K09593 GAB1; GRB2-associated-binding protein 1
|
05214 Glioma [PATH:pale05214]
|
102891552 EGF; pro-epidermal growth factor isoform X1
102887662 TGFA; protransforming growth factor alpha isoform X1
102893495 EGFR; epidermal growth factor receptor
102893670 PDGFA; platelet-derived growth factor subunit A
102897699 PDGFB; platelet-derived growth factor subunit B isoform X1
102895362 PDGFRA; platelet-derived growth factor receptor alpha isoform X1
102887643 PDGFRB; platelet-derived growth factor receptor beta isoform X1
102890331 IGF1; insulin-like growth factor I isoform X3
102885962 IGF1R; insulin-like growth factor 1 receptor
102896228 PLCG1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1
102883128 PLCG2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
102894226 CALM2; calmodulin-2 isoform X1
102897273 CALM3; calmodulin-3
102886058 CALM1; calmodulin-1
102884196 CALML6; calmodulin-like protein 6
102891673 calmodulin-like
102893109 CALML4; LOW QUALITY PROTEIN: calmodulin-like protein 4
102881744 calmodulin-like
102896085 CAMK1G; calcium/calmodulin-dependent protein kinase type 1G
102893878 CAMK1D; calcium/calmodulin-dependent protein kinase type 1D
102883933 CAMK1; calcium/calmodulin-dependent protein kinase type 1 isoform X1
102888982 CAMK2B; calcium/calmodulin-dependent protein kinase type II subunit beta
102888385 CAMK2A; calcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1
102880869 CAMK2D; calcium/calmodulin-dependent protein kinase type II subunit delta
102896030 CAMK2G; calcium/calmodulin-dependent protein kinase type II subunit gamma
102879333 CAMK4; calcium/calmodulin-dependent protein kinase type IV
102887078 PRKCA; protein kinase C alpha type
102880663 PRKCB; protein kinase C beta type
102888961 PRKCG; protein kinase C gamma type
102894443 SHC1; LOW QUALITY PROTEIN: SHC-transforming protein 1
102885958 SHC2; SHC-transforming protein 2
102879956 SHC3; SHC-transforming protein 3
102888926 SHC4; SHC-transforming protein 4
102878822 GRB2; growth factor receptor-bound protein 2 isoform X1
102882462 SOS1; son of sevenless homolog 1 isoform X1
102889597 SOS2; son of sevenless homolog 2
102896270 HRAS; GTPase HRas isoform X3
102895590 KRAS; GTPase KRas isoform X1
102885950 NRAS; GTPase NRas isoform X2
102877877 ARAF; serine/threonine-protein kinase A-Raf isoform X2
102878393 BRAF; serine/threonine-protein kinase B-raf isoform X2
102893439 RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X1
102897122 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 isoform X1
102879034 MAP2K2; dual specificity mitogen-activated protein kinase kinase 2
102895390 MAPK1; mitogen-activated protein kinase 1
102885749 MAPK3; mitogen-activated protein kinase 3
102889227 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
102880320 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
102889576 PIK3CD; LOW QUALITY PROTEIN: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
102879163 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1
102891637 phosphatidylinositol 3-kinase regulatory subunit gamma isoform X3
102879453 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
102885144 AKT1; RAC-alpha serine/threonine-protein kinase isoform X1
102879337 AKT3; RAC-gamma serine/threonine-protein kinase isoform X1
102898305 AKT2; LOW QUALITY PROTEIN: RAC-beta serine/threonine-protein kinase
102885092 MTOR; serine/threonine-protein kinase mTOR
102881949 PTEN; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X1
102896422 LOW QUALITY PROTEIN: cyclin-dependent kinase inhibitor 2A
102884281 MDM2; E3 ubiquitin-protein ligase Mdm2
102889604 TP53; cellular tumor antigen p53
102894049 CDKN1A; cyclin-dependent kinase inhibitor 1
102885330 CCND1; G1/S-specific cyclin-D1
102894222 CDK4; cyclin-dependent kinase 4
102896272 CDK6; cyclin-dependent kinase 6
102893019 RB1; retinoblastoma-associated protein
102895276 E2F1; transcription factor E2F1
102884459 E2F2; transcription factor E2F2 isoform X1
102887239 E2F3; transcription factor E2F3 isoform X1
102886440 GADD45A; growth arrest and DNA damage-inducible protein GADD45 alpha
102878191 GADD45G; growth arrest and DNA damage-inducible protein GADD45 gamma
102885790 GADD45B; growth arrest and DNA damage-inducible protein GADD45 beta
102885135 BAX; apoptosis regulator BAX isoform X1
102883540 BAK1; bcl-2 homologous antagonist/killer
102879479 DDB2; DNA damage-binding protein 2 isoform X1
102890888 POLK; DNA polymerase kappa isoform X1
|
K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K04363 PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05459 IGF1; insulin-like growth factor 1
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K08794 CAMK1; calcium/calmodulin-dependent protein kinase I [EC:2.7.11.17]
K08794 CAMK1; calcium/calmodulin-dependent protein kinase I [EC:2.7.11.17]
K08794 CAMK1; calcium/calmodulin-dependent protein kinase I [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K05869 CAMK4; calcium/calmodulin-dependent protein kinase IV [EC:2.7.11.17]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53; tumor protein p53
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04503 CCND1; G1/S-specific cyclin-D1
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
|
05216 Thyroid cancer [PATH:pale05216]
|
102878133 RET; proto-oncogene tyrosine-protein kinase receptor Ret isoform X4
102879174 CCDC6; coiled-coil domain-containing protein 6
102896808 NCOA4; nuclear receptor coactivator 4 isoform X3
112472150 NTRK1; high affinity nerve growth factor receptor
102898874 TPM3; tropomyosin alpha-3 chain isoform X1
102887317 TPR; LOW QUALITY PROTEIN: nucleoprotein TPR
102892687 TFG; protein TFG isoform X1
102896270 HRAS; GTPase HRas isoform X3
102885950 NRAS; GTPase NRas isoform X2
102895590 KRAS; GTPase KRas isoform X1
102878393 BRAF; serine/threonine-protein kinase B-raf isoform X2
102897122 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 isoform X1
102879034 MAP2K2; dual specificity mitogen-activated protein kinase kinase 2
102895390 MAPK1; mitogen-activated protein kinase 1
102885749 MAPK3; mitogen-activated protein kinase 3
102894983 PAX8; paired box protein Pax-8 isoform X1
102892450 PPARG; peroxisome proliferator-activated receptor gamma isoform X1
102881572 RXRA; retinoic acid receptor RXR-alpha
102888877 RXRB; retinoic acid receptor RXR-beta isoform X1
102897820 RXRG; retinoic acid receptor RXR-gamma
102889604 TP53; cellular tumor antigen p53
102894049 CDKN1A; cyclin-dependent kinase inhibitor 1
102886440 GADD45A; growth arrest and DNA damage-inducible protein GADD45 alpha
102878191 GADD45G; growth arrest and DNA damage-inducible protein GADD45 gamma
102885790 GADD45B; growth arrest and DNA damage-inducible protein GADD45 beta
102885135 BAX; apoptosis regulator BAX isoform X1
102883540 BAK1; bcl-2 homologous antagonist/killer
102879479 DDB2; DNA damage-binding protein 2 isoform X1
102890888 POLK; DNA polymerase kappa isoform X1
102886394 CDH1; cadherin-1 isoform X1
102880017 CTNNB1; LOW QUALITY PROTEIN: catenin beta-1
102885788 TCF7; transcription factor 7 isoform X4
102886093 TCF7L1; transcription factor 7-like 1
102880370 TCF7L2; transcription factor 7-like 2 isoform X2
102886933 LEF1; lymphoid enhancer-binding factor 1 isoform X1
102895524 MYC; myc proto-oncogene protein
102885330 CCND1; G1/S-specific cyclin-D1
|
K05126 RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
K09288 CCDC6; coiled-coil domain-containing protein 6
K09289 NCOA4; nuclear receptor coactivator 4
K03176 NTRK1; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K09290 TPM3; tropomyosin 3
K09291 TPR; nucleoprotein TPR
K09292 TFG; protein TFG
K02833 HRAS; GTPase HRas
K07828 NRAS; GTPase NRas
K07827 KRAS; GTPase KRas
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K09293 PAX8; paired box protein 8
K08530 NR1C3; peroxisome proliferator-activated receptor gamma
K08524 RXRA; retinoid X receptor alpha
K08525 RXRB; retinoid X receptor beta
K08526 RXRG; retinoid X receptor gamma
K04451 TP53; tumor protein p53
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K05689 CDH1; cadherin 1, type 1, E-cadherin
K02105 CTNNB1; catenin beta 1
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; G1/S-specific cyclin-D1
|
05221 Acute myeloid leukemia [PATH:pale05221]
|
05220 Chronic myeloid leukemia [PATH:pale05220]
|
102897172 BCR; breakpoint cluster region protein
102895947 ABL1; tyrosine-protein kinase ABL1
102898080 CRKL; crk-like protein
102885553 CRK; adapter molecule crk isoform X1
102895335 CBL; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase CBL
102889227 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
102880320 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
102889576 PIK3CD; LOW QUALITY PROTEIN: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
102879163 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1
102891637 phosphatidylinositol 3-kinase regulatory subunit gamma isoform X3
102879453 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
102885144 AKT1; RAC-alpha serine/threonine-protein kinase isoform X1
102879337 AKT3; RAC-gamma serine/threonine-protein kinase isoform X1
102898305 AKT2; LOW QUALITY PROTEIN: RAC-beta serine/threonine-protein kinase
102877892 BAD; bcl2-associated agonist of cell death isoform X1
102887704 BCL2L1; bcl-2-like protein 1
102879469 CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
102893261 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1
102880203 IKBKG; NF-kappa-B essential modulator isoform X1
102891056 NFKBIA; NF-kappa-B inhibitor alpha
102880692 NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1
102878395 RELA; transcription factor p65
102884281 MDM2; E3 ubiquitin-protein ligase Mdm2
102889604 TP53; cellular tumor antigen p53
102880085 CDKN1B; cyclin-dependent kinase inhibitor 1B
102878822 GRB2; growth factor receptor-bound protein 2 isoform X1
102882788 GAB2; GRB2-associated-binding protein 2 isoform X2
102889219 PTPN11; LOW QUALITY PROTEIN: tyrosine-protein phosphatase non-receptor type 11
102887205 tyrosine-protein phosphatase non-receptor type 11
102882462 SOS1; son of sevenless homolog 1 isoform X1
102889597 SOS2; son of sevenless homolog 2
102896270 HRAS; GTPase HRas isoform X3
102895590 KRAS; GTPase KRas isoform X1
102885950 NRAS; GTPase NRas isoform X2
102893439 RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X1
102877877 ARAF; serine/threonine-protein kinase A-Raf isoform X2
102878393 BRAF; serine/threonine-protein kinase B-raf isoform X2
102897122 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 isoform X1
102879034 MAP2K2; dual specificity mitogen-activated protein kinase kinase 2
102895390 MAPK1; mitogen-activated protein kinase 1
102885749 MAPK3; mitogen-activated protein kinase 3
102894443 SHC1; LOW QUALITY PROTEIN: SHC-transforming protein 1
102885958 SHC2; SHC-transforming protein 2
102879956 SHC3; SHC-transforming protein 3
102888926 SHC4; SHC-transforming protein 4
102895524 MYC; myc proto-oncogene protein
102884638 signal transducer and activator of transcription 5A
102884882 signal transducer and activator of transcription 5B isoform X1
102896422 LOW QUALITY PROTEIN: cyclin-dependent kinase inhibitor 2A
102894049 CDKN1A; cyclin-dependent kinase inhibitor 1
102885330 CCND1; G1/S-specific cyclin-D1
102894222 CDK4; cyclin-dependent kinase 4
102896272 CDK6; cyclin-dependent kinase 6
102893019 RB1; retinoblastoma-associated protein
102895276 E2F1; transcription factor E2F1
102884459 E2F2; transcription factor E2F2 isoform X1
102887239 E2F3; transcription factor E2F3 isoform X1
102886440 GADD45A; growth arrest and DNA damage-inducible protein GADD45 alpha
102878191 GADD45G; growth arrest and DNA damage-inducible protein GADD45 gamma
102885790 GADD45B; growth arrest and DNA damage-inducible protein GADD45 beta
102885135 BAX; apoptosis regulator BAX isoform X1
102883540 BAK1; bcl-2 homologous antagonist/killer
102879479 DDB2; DNA damage-binding protein 2 isoform X1
102890888 POLK; DNA polymerase kappa isoform X1
102884154 TGFB1; transforming growth factor beta-1
102881295 TGFB2; transforming growth factor beta-2 isoform X2
102893304 TGFB3; transforming growth factor beta-3
102880759 TGFBR1; TGF-beta receptor type-1 isoform X2
102889618 TGFBR2; TGF-beta receptor type-2 isoform X1
102895268 SMAD3; mothers against decapentaplegic homolog 3
102886521 SMAD4; mothers against decapentaplegic homolog 4
102878481 MECOM; MDS1 and EVI1 complex locus protein isoform X1
102879444 RUNX1; runt-related transcription factor 1
102899024 CTBP1; C-terminal-binding protein 1 isoform X1
102879836 CTBP2; C-terminal-binding protein 2 isoform X3
102890938 HDAC1; histone deacetylase 1
102878536 HDAC2; histone deacetylase 2
|
K08878 BCR1; breakpoint cluster region protein [EC:2.7.11.1]
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K04438 CRK; C-crk adapter molecule crk
K04438 CRK; C-crk adapter molecule crk
K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53; tumor protein p53
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K04364 GRB2; growth factor receptor-bound protein 2
K08091 GAB2; GRB2-associated-binding protein 2
K07293 PTPN11; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K07293 PTPN11; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04377 MYC; Myc proto-oncogene protein
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04503 CCND1; G1/S-specific cyclin-D1
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04462 MECOM; [histone H3]-lysine9 N-methyltransferase (ecotropic virus integration site 1 protein) [EC:2.1.1.367]
K08367 RUNX1; runt-related transcription factor 1
K04496 CTBP; C-terminal binding protein [EC:1.1.1.428]
K04496 CTBP; C-terminal binding protein [EC:1.1.1.428]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
|
05217 Basal cell carcinoma [PATH:pale05217]
|
102889604 TP53; cellular tumor antigen p53
102894049 CDKN1A; cyclin-dependent kinase inhibitor 1
102886440 GADD45A; growth arrest and DNA damage-inducible protein GADD45 alpha
102878191 GADD45G; growth arrest and DNA damage-inducible protein GADD45 gamma
102885790 GADD45B; growth arrest and DNA damage-inducible protein GADD45 beta
102885135 BAX; apoptosis regulator BAX isoform X1
102883540 BAK1; bcl-2 homologous antagonist/killer
102879479 DDB2; DNA damage-binding protein 2 isoform X1
102890888 POLK; DNA polymerase kappa isoform X1
102882514 SHH; sonic hedgehog protein
102884350 PTCH1; LOW QUALITY PROTEIN: protein patched homolog 1
102892668 SMO; smoothened homolog
102882111 KIF7; kinesin-like protein KIF7
102892289 SUFU; suppressor of fused homolog isoform X1
102889893 GLI1; zinc finger protein GLI1 isoform X1
102880962 GLI2; zinc finger protein GLI2 isoform X1
102894872 GLI3; transcriptional activator GLI3 isoform X1
102886941 BMP2; bone morphogenetic protein 2
102881920 BMP4; bone morphogenetic protein 4 isoform X1
102880475 HHIP; hedgehog-interacting protein
102887248 PTCH2; protein patched homolog 2
102888016 WNT1; proto-oncogene Wnt-1
102880959 WNT2B; protein Wnt-2b isoform X1
102885080 WNT2; protein Wnt-2
102895795 WNT3A; protein Wnt-3a
102877979 WNT3; proto-oncogene Wnt-3
102888866 WNT4; protein Wnt-4
102890342 WNT5A; protein Wnt-5a isoform X5
102881682 WNT5B; protein Wnt-5b isoform X2
102882368 WNT6; protein Wnt-6 isoform X1
102888597 WNT7A; protein Wnt-7a
102898026 WNT7B; protein Wnt-7b isoform X1
102896480 WNT8A; protein Wnt-8a
102878209 WNT8B; protein Wnt-8b
102885223 protein Wnt-9b
102884543 WNT9A; protein Wnt-9a
102882121 WNT10A; protein Wnt-10a
102888263 WNT10B; protein Wnt-10b
102877879 WNT11; protein Wnt-11
102882050 WNT16; LOW QUALITY PROTEIN: protein Wnt-16
102880538 FZD7; frizzled-7
102895634 FZD1; frizzled-1
102884150 FZD2; frizzled-2
102890038 FZD3; frizzled-3 isoform X1
102892989 FZD4; LOW QUALITY PROTEIN: frizzled-4
102877864 FZD8; LOW QUALITY PROTEIN: frizzled-8
102883426 FZD5; LOW QUALITY PROTEIN: frizzled-5
102890002 FZD6; frizzled-6
102894135 FZD10; frizzled-10
102878169 FZD9; frizzled-9
102895469 DVL3; segment polarity protein dishevelled homolog DVL-3 isoform X1
102880039 DVL2; segment polarity protein dishevelled homolog DVL-2 isoform X1
102881158 DVL1; segment polarity protein dishevelled homolog DVL-1 isoform X1
102882441 GSK3B; glycogen synthase kinase-3 beta isoform X4
102878657 AXIN1; axin-1 isoform X1
102885831 AXIN2; axin-2
102880260 APC; adenomatous polyposis coli protein isoform X3
102891886 APC2; adenomatous polyposis coli protein 2
102880017 CTNNB1; LOW QUALITY PROTEIN: catenin beta-1
102885788 TCF7; transcription factor 7 isoform X4
102886093 TCF7L1; transcription factor 7-like 1
102880370 TCF7L2; transcription factor 7-like 2 isoform X2
102886933 LEF1; lymphoid enhancer-binding factor 1 isoform X1
|
K04451 TP53; tumor protein p53
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K11988 SHH; sonic hedgehog
K06225 PTCH1; patched 1
K06226 SMO; smoothened
K18806 KIF7; kinesin family member 7
K06229 SUFU; suppressor of fused
K16797 GLI1; zinc finger protein GLI1
K16798 GLI2; zinc finger protein GLI2
K06230 GLI3; zinc finger protein GLI3
K21283 BMP2; bone morphogenetic protein 2
K04662 BMP4; bone morphogenetic protein 4
K06231 HHIP; hedgehog interacting protein
K11101 PTCH2; patched 2
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7; frizzled 1/7
K02432 FZD1_7; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4; frizzled 4
K02375 FZD5_8; frizzled 5/8
K02375 FZD5_8; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10; frizzled 9/10
K02842 FZD9_10; frizzled 9/10
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02085 APC; adenomatosis polyposis coli protein
K02085 APC; adenomatosis polyposis coli protein
K02105 CTNNB1; catenin beta 1
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
|
05218 Melanoma [PATH:pale05218]
|
102894192 FGF1; fibroblast growth factor 1 isoform X1
107196088 FGF2; fibroblast growth factor 2
102895922 FGF10; fibroblast growth factor 10
102887777 FGF7; fibroblast growth factor 7
102892141 FGF6; fibroblast growth factor 6
102895642 FGF5; fibroblast growth factor 5
102890153 FGF16; fibroblast growth factor 16
102893226 FGF8; fibroblast growth factor 8 isoform X4
102894115 FGF18; fibroblast growth factor 18
102888098 FGF20; fibroblast growth factor 20
102893244 FGF4; fibroblast growth factor 4
102894279 FGF17; fibroblast growth factor 17 isoform X1
102887882 FGF9; fibroblast growth factor 9
102896895 FGF22; fibroblast growth factor 22
102885081 FGF19; fibroblast growth factor 19
102886540 FGF21; fibroblast growth factor 21
102883346 FGF23; fibroblast growth factor 23
102884470 HGF; hepatocyte growth factor isoform X1
102890331 IGF1; insulin-like growth factor I isoform X3
102893670 PDGFA; platelet-derived growth factor subunit A
102897699 PDGFB; platelet-derived growth factor subunit B isoform X1
102894123 PDGFD; platelet-derived growth factor D isoform X1
102890668 PDGFC; platelet-derived growth factor C isoform X1
102891552 EGF; pro-epidermal growth factor isoform X1
102898943 FGFR1; fibroblast growth factor receptor 1 isoform X9
102885990 MET; hepatocyte growth factor receptor isoform X1
102885962 IGF1R; insulin-like growth factor 1 receptor
102895362 PDGFRA; platelet-derived growth factor receptor alpha isoform X1
102887643 PDGFRB; platelet-derived growth factor receptor beta isoform X1
102893495 EGFR; epidermal growth factor receptor
102896270 HRAS; GTPase HRas isoform X3
102895590 KRAS; GTPase KRas isoform X1
102885950 NRAS; GTPase NRas isoform X2
102877877 ARAF; serine/threonine-protein kinase A-Raf isoform X2
102878393 BRAF; serine/threonine-protein kinase B-raf isoform X2
102893439 RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X1
102897122 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 isoform X1
102879034 MAP2K2; dual specificity mitogen-activated protein kinase kinase 2
102895390 MAPK1; mitogen-activated protein kinase 1
102885749 MAPK3; mitogen-activated protein kinase 3
102885330 CCND1; G1/S-specific cyclin-D1
102894222 CDK4; cyclin-dependent kinase 4
102889227 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
102880320 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
102889576 PIK3CD; LOW QUALITY PROTEIN: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
102879163 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1
102891637 phosphatidylinositol 3-kinase regulatory subunit gamma isoform X3
102879453 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
102885144 AKT1; RAC-alpha serine/threonine-protein kinase isoform X1
102879337 AKT3; RAC-gamma serine/threonine-protein kinase isoform X1
102898305 AKT2; LOW QUALITY PROTEIN: RAC-beta serine/threonine-protein kinase
102877892 BAD; bcl2-associated agonist of cell death isoform X1
102881949 PTEN; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X1
102896422 LOW QUALITY PROTEIN: cyclin-dependent kinase inhibitor 2A
102884281 MDM2; E3 ubiquitin-protein ligase Mdm2
102889604 TP53; cellular tumor antigen p53
102894049 CDKN1A; cyclin-dependent kinase inhibitor 1
102896272 CDK6; cyclin-dependent kinase 6
102893019 RB1; retinoblastoma-associated protein
102895276 E2F1; transcription factor E2F1
102884459 E2F2; transcription factor E2F2 isoform X1
102887239 E2F3; transcription factor E2F3 isoform X1
102886394 CDH1; cadherin-1 isoform X1
102886440 GADD45A; growth arrest and DNA damage-inducible protein GADD45 alpha
102878191 GADD45G; growth arrest and DNA damage-inducible protein GADD45 gamma
102885790 GADD45B; growth arrest and DNA damage-inducible protein GADD45 beta
102885135 BAX; apoptosis regulator BAX isoform X1
102883540 BAK1; bcl-2 homologous antagonist/killer
102879479 DDB2; DNA damage-binding protein 2 isoform X1
102890888 POLK; DNA polymerase kappa isoform X1
102899015 MITF; microphthalmia-associated transcription factor isoform X1
|
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K05460 HGF; hepatocyte growth factor
K05459 IGF1; insulin-like growth factor 1
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K05450 PDGFC_D; platelet derived growth factor C/D
K05450 PDGFC_D; platelet derived growth factor C/D
K04357 EGF; epidermal growth factor
K04362 FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04363 PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04503 CCND1; G1/S-specific cyclin-D1
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53; tumor protein p53
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K05689 CDH1; cadherin 1, type 1, E-cadherin
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K09455 MITF; microphthalmia-associated transcription factor
|
05211 Renal cell carcinoma [PATH:pale05211]
|
05219 Bladder cancer [PATH:pale05219]
|
05215 Prostate cancer [PATH:pale05215]
|
05213 Endometrial cancer [PATH:pale05213]
|
102891552 EGF; pro-epidermal growth factor isoform X1
102893495 EGFR; epidermal growth factor receptor
102889227 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
102880320 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
102889576 PIK3CD; LOW QUALITY PROTEIN: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
102879163 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1
102891637 phosphatidylinositol 3-kinase regulatory subunit gamma isoform X3
102879453 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
102881949 PTEN; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X1
102896950 PDPK1; 3-phosphoinositide-dependent protein kinase 1
102887513 ILK; integrin-linked protein kinase isoform X1
102885144 AKT1; RAC-alpha serine/threonine-protein kinase isoform X1
102879337 AKT3; RAC-gamma serine/threonine-protein kinase isoform X1
102898305 AKT2; LOW QUALITY PROTEIN: RAC-beta serine/threonine-protein kinase
102878565 CASP9; caspase-9
102877892 BAD; bcl2-associated agonist of cell death isoform X1
102890472 FOXO3; forkhead box protein O3
102878822 GRB2; growth factor receptor-bound protein 2 isoform X1
102882462 SOS1; son of sevenless homolog 1 isoform X1
102889597 SOS2; son of sevenless homolog 2
102896270 HRAS; GTPase HRas isoform X3
102895590 KRAS; GTPase KRas isoform X1
102885950 NRAS; GTPase NRas isoform X2
102877877 ARAF; serine/threonine-protein kinase A-Raf isoform X2
102878393 BRAF; serine/threonine-protein kinase B-raf isoform X2
102893439 RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X1
102897122 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 isoform X1
102879034 MAP2K2; dual specificity mitogen-activated protein kinase kinase 2
102895390 MAPK1; mitogen-activated protein kinase 1
102885749 MAPK3; mitogen-activated protein kinase 3
102878877 ELK1; ETS domain-containing protein Elk-1 isoform X1
102898392 MLH1; DNA mismatch repair protein Mlh1 isoform X1
102886394 CDH1; cadherin-1 isoform X1
102880017 CTNNB1; LOW QUALITY PROTEIN: catenin beta-1
102893948 CTNNA2; catenin alpha-2 isoform X3
102881133 CTNNA3; catenin alpha-3
102891804 CTNNA1; catenin alpha-1
102878657 AXIN1; axin-1 isoform X1
102885831 AXIN2; axin-2
102880260 APC; adenomatous polyposis coli protein isoform X3
102891886 APC2; adenomatous polyposis coli protein 2
102882441 GSK3B; glycogen synthase kinase-3 beta isoform X4
102885788 TCF7; transcription factor 7 isoform X4
102886093 TCF7L1; transcription factor 7-like 1
102880370 TCF7L2; transcription factor 7-like 2 isoform X2
102886933 LEF1; lymphoid enhancer-binding factor 1 isoform X1
102895524 MYC; myc proto-oncogene protein
102885330 CCND1; G1/S-specific cyclin-D1
102889604 TP53; cellular tumor antigen p53
102894049 CDKN1A; cyclin-dependent kinase inhibitor 1
102886440 GADD45A; growth arrest and DNA damage-inducible protein GADD45 alpha
102878191 GADD45G; growth arrest and DNA damage-inducible protein GADD45 gamma
102885790 GADD45B; growth arrest and DNA damage-inducible protein GADD45 beta
102885135 BAX; apoptosis regulator BAX isoform X1
102883540 BAK1; bcl-2 homologous antagonist/killer
102879479 DDB2; DNA damage-binding protein 2 isoform X1
102890888 POLK; DNA polymerase kappa isoform X1
102885300 ERBB2; LOW QUALITY PROTEIN: receptor tyrosine-protein kinase erbB-2
|
K04357 EGF; epidermal growth factor
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K06272 ILK; integrin-linked kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02158 BAD; Bcl-2-antagonist of cell death
K09408 FOXO3; forkhead box protein O3
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04375 ELK1; ETS domain-containing protein Elk-1
K08734 MLH1; DNA mismatch repair protein MLH1
K05689 CDH1; cadherin 1, type 1, E-cadherin
K02105 CTNNB1; catenin beta 1
K05691 CTNNA; catenin alpha
K05691 CTNNA; catenin alpha
K05691 CTNNA; catenin alpha
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02085 APC; adenomatosis polyposis coli protein
K02085 APC; adenomatosis polyposis coli protein
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; G1/S-specific cyclin-D1
K04451 TP53; tumor protein p53
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
|
05224 Breast cancer [PATH:pale05224]
|
102877910 ESR1; estrogen receptor isoform X1
102878324 ESR2; estrogen receptor beta isoform X2
102885576 NCOA1; nuclear receptor coactivator 1 isoform X1
102892705 NCOA3; nuclear receptor coactivator 3 isoform X1
102891428 FOS; proto-oncogene c-Fos
102896121 JUN; transcription factor AP-1
102894100 SP1; transcription factor Sp1 isoform X1
102885330 CCND1; G1/S-specific cyclin-D1
102895524 MYC; myc proto-oncogene protein
102882873 PGR; progesterone receptor isoform X1
102888016 WNT1; proto-oncogene Wnt-1
102888866 WNT4; protein Wnt-4
102896284 TNFSF11; tumor necrosis factor ligand superfamily member 11
102885300 ERBB2; LOW QUALITY PROTEIN: receptor tyrosine-protein kinase erbB-2
102894192 FGF1; fibroblast growth factor 1 isoform X1
107196088 FGF2; fibroblast growth factor 2
102895922 FGF10; fibroblast growth factor 10
102887777 FGF7; fibroblast growth factor 7
102892141 FGF6; fibroblast growth factor 6
102895642 FGF5; fibroblast growth factor 5
102890153 FGF16; fibroblast growth factor 16
102893226 FGF8; fibroblast growth factor 8 isoform X4
102894115 FGF18; fibroblast growth factor 18
102888098 FGF20; fibroblast growth factor 20
102893244 FGF4; fibroblast growth factor 4
102894279 FGF17; fibroblast growth factor 17 isoform X1
102887882 FGF9; fibroblast growth factor 9
102896895 FGF22; fibroblast growth factor 22
102885081 FGF19; fibroblast growth factor 19
102886540 FGF21; fibroblast growth factor 21
102883346 FGF23; fibroblast growth factor 23
102898943 FGFR1; fibroblast growth factor receptor 1 isoform X9
102890331 IGF1; insulin-like growth factor I isoform X3
102885962 IGF1R; insulin-like growth factor 1 receptor
102891552 EGF; pro-epidermal growth factor isoform X1
102893495 EGFR; epidermal growth factor receptor
102895969 KIT; mast/stem cell growth factor receptor Kit
102894443 SHC1; LOW QUALITY PROTEIN: SHC-transforming protein 1
102885958 SHC2; SHC-transforming protein 2
102879956 SHC3; SHC-transforming protein 3
102888926 SHC4; SHC-transforming protein 4
102878822 GRB2; growth factor receptor-bound protein 2 isoform X1
102882462 SOS1; son of sevenless homolog 1 isoform X1
102889597 SOS2; son of sevenless homolog 2
102896270 HRAS; GTPase HRas isoform X3
102895590 KRAS; GTPase KRas isoform X1
102885950 NRAS; GTPase NRas isoform X2
102877877 ARAF; serine/threonine-protein kinase A-Raf isoform X2
102878393 BRAF; serine/threonine-protein kinase B-raf isoform X2
102893439 RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X1
102897122 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 isoform X1
102879034 MAP2K2; dual specificity mitogen-activated protein kinase kinase 2
102895390 MAPK1; mitogen-activated protein kinase 1
102885749 MAPK3; mitogen-activated protein kinase 3
102889227 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
102880320 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
102889576 PIK3CD; LOW QUALITY PROTEIN: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
102879163 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1
102891637 phosphatidylinositol 3-kinase regulatory subunit gamma isoform X3
102879453 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
102881949 PTEN; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X1
102885144 AKT1; RAC-alpha serine/threonine-protein kinase isoform X1
102879337 AKT3; RAC-gamma serine/threonine-protein kinase isoform X1
102898305 AKT2; LOW QUALITY PROTEIN: RAC-beta serine/threonine-protein kinase
102885092 MTOR; serine/threonine-protein kinase mTOR
102891214 RPS6KB2; ribosomal protein S6 kinase beta-2 isoform X1
102889369 RPS6KB1; ribosomal protein S6 kinase beta-1 isoform X1
102883084 JAG1; protein jagged-1
102891267 JAG2; protein jagged-2
102891557 DLL4; delta-like protein 4 isoform X2
102882856 DLL3; delta-like protein 3
102892930 DLL1; delta-like protein 1
102889752 NOTCH1; neurogenic locus notch homolog protein 1
102887446 NOTCH2; LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 2
102898799 NOTCH3; neurogenic locus notch homolog protein 3
102895453 NOTCH4; neurogenic locus notch homolog protein 4
102890128 HES1; transcription factor HES-1
102893116 HES5; transcription factor HES-5
102893208 hairy/enhancer-of-split related with YRPW motif protein 1
102891586 HEY2; hairy/enhancer-of-split related with YRPW motif protein 2
102895448 HEYL; hairy/enhancer-of-split related with YRPW motif-like protein
102889771 FLT4; vascular endothelial growth factor receptor 3
102894049 CDKN1A; cyclin-dependent kinase inhibitor 1
102894780 NFKB2; nuclear factor NF-kappa-B p100 subunit isoform X1
102880959 WNT2B; protein Wnt-2b isoform X1
102885080 WNT2; protein Wnt-2
102895795 WNT3A; protein Wnt-3a
102877979 WNT3; proto-oncogene Wnt-3
102890342 WNT5A; protein Wnt-5a isoform X5
102881682 WNT5B; protein Wnt-5b isoform X2
102882368 WNT6; protein Wnt-6 isoform X1
102888597 WNT7A; protein Wnt-7a
102898026 WNT7B; protein Wnt-7b isoform X1
102896480 WNT8A; protein Wnt-8a
102878209 WNT8B; protein Wnt-8b
102885223 protein Wnt-9b
102884543 WNT9A; protein Wnt-9a
102882121 WNT10A; protein Wnt-10a
102888263 WNT10B; protein Wnt-10b
102877879 WNT11; protein Wnt-11
102882050 WNT16; LOW QUALITY PROTEIN: protein Wnt-16
102880538 FZD7; frizzled-7
102895634 FZD1; frizzled-1
102884150 FZD2; frizzled-2
102890038 FZD3; frizzled-3 isoform X1
102892989 FZD4; LOW QUALITY PROTEIN: frizzled-4
102877864 FZD8; LOW QUALITY PROTEIN: frizzled-8
102883426 FZD5; LOW QUALITY PROTEIN: frizzled-5
102890002 FZD6; frizzled-6
102894135 FZD10; frizzled-10
102878169 FZD9; frizzled-9
102894479 LRP5; low-density lipoprotein receptor-related protein 5
102878233 LRP6; low-density lipoprotein receptor-related protein 6
102895469 DVL3; segment polarity protein dishevelled homolog DVL-3 isoform X1
102880039 DVL2; segment polarity protein dishevelled homolog DVL-2 isoform X1
102881158 DVL1; segment polarity protein dishevelled homolog DVL-1 isoform X1
102896339 LOW QUALITY PROTEIN: proto-oncogene FRAT1
102882441 GSK3B; glycogen synthase kinase-3 beta isoform X4
102878657 AXIN1; axin-1 isoform X1
102885831 AXIN2; axin-2
102880260 APC; adenomatous polyposis coli protein isoform X3
102891886 APC2; adenomatous polyposis coli protein 2
102880017 CTNNB1; LOW QUALITY PROTEIN: catenin beta-1
102884974 CSNK1A1; casein kinase I isoform X3
102885788 TCF7; transcription factor 7 isoform X4
102886093 TCF7L1; transcription factor 7-like 1
102880370 TCF7L2; transcription factor 7-like 2 isoform X2
102886933 LEF1; lymphoid enhancer-binding factor 1 isoform X1
102889604 TP53; cellular tumor antigen p53
102886440 GADD45A; growth arrest and DNA damage-inducible protein GADD45 alpha
102878191 GADD45G; growth arrest and DNA damage-inducible protein GADD45 gamma
102885790 GADD45B; growth arrest and DNA damage-inducible protein GADD45 beta
102885135 BAX; apoptosis regulator BAX isoform X1
102883540 BAK1; bcl-2 homologous antagonist/killer
102879479 DDB2; DNA damage-binding protein 2 isoform X1
102890888 POLK; DNA polymerase kappa isoform X1
102894222 CDK4; cyclin-dependent kinase 4
102896272 CDK6; cyclin-dependent kinase 6
102893019 RB1; retinoblastoma-associated protein
102895276 E2F1; transcription factor E2F1
102884459 E2F2; transcription factor E2F2 isoform X1
102887239 E2F3; transcription factor E2F3 isoform X1
102895982 BRCA1; breast cancer type 1 susceptibility protein isoform X1
102896802 BRCA2; breast cancer type 2 susceptibility protein
|
K08550 ESR1; estrogen receptor alpha
K08551 ESR2; estrogen receptor beta
K09101 NCOA1; nuclear receptor coactivator 1 [EC:2.3.1.48]
K11256 NCOA3; nuclear receptor coactivator 3 [EC:2.3.1.48]
K04379 FOS; proto-oncogene protein c-fos
K04448 JUN; transcription factor AP-1
K04684 SP1; transcription factor Sp1
K04503 CCND1; G1/S-specific cyclin-D1
K04377 MYC; Myc proto-oncogene protein
K08556 PGR; progesterone receptor
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00408 WNT4; wingless-type MMTV integration site family, member 4
K05473 TNFSF11; tumor necrosis factor ligand superfamily member 11
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K04362 FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05459 IGF1; insulin-like growth factor 1
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04357 EGF; epidermal growth factor
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05091 KIT; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K06052 JAG1; jagged-1
K21635 JAG2; jagged-2
K06051 DLL; delta
K06051 DLL; delta
K06051 DLL; delta
K02599 NOTCH1; Notch 1
K20994 NOTCH2; Notch 2
K20995 NOTCH3; Notch 3
K20996 NOTCH4; Notch 4
K06054 HES1; hairy and enhancer of split 1
K06055 HES5; hairy and enhancer of split 5
K09091 HEY; hairy and enhancer of split related with YRPW motif
K09091 HEY; hairy and enhancer of split related with YRPW motif
K09091 HEY; hairy and enhancer of split related with YRPW motif
K05097 FLT4; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04469 NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7; frizzled 1/7
K02432 FZD1_7; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4; frizzled 4
K02375 FZD5_8; frizzled 5/8
K02375 FZD5_8; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10; frizzled 9/10
K02842 FZD9_10; frizzled 9/10
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K03069 FRAT1; frequently rearranged in advanced T-cell lymphomas 1
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02085 APC; adenomatosis polyposis coli protein
K02085 APC; adenomatosis polyposis coli protein
K02105 CTNNB1; catenin beta 1
K08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K04451 TP53; tumor protein p53
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
K08775 BRCA2; breast cancer 2 susceptibility protein
|
05222 Small cell lung cancer [PATH:pale05222]
|
102883490 FHIT; bis(5'-adenosyl)-triphosphatase isoform X2
102886545 RARB; retinoic acid receptor beta
102881572 RXRA; retinoic acid receptor RXR-alpha
102888877 RXRB; retinoic acid receptor RXR-beta isoform X1
102897820 RXRG; retinoic acid receptor RXR-gamma
102889604 TP53; cellular tumor antigen p53
102894049 CDKN1A; cyclin-dependent kinase inhibitor 1
102886440 GADD45A; growth arrest and DNA damage-inducible protein GADD45 alpha
102878191 GADD45G; growth arrest and DNA damage-inducible protein GADD45 gamma
102885790 GADD45B; growth arrest and DNA damage-inducible protein GADD45 beta
102885135 BAX; apoptosis regulator BAX isoform X1
102883540 BAK1; bcl-2 homologous antagonist/killer
102879479 DDB2; DNA damage-binding protein 2 isoform X1
102890888 POLK; DNA polymerase kappa isoform X1
102896443 BCL2; apoptosis regulator Bcl-2
102879159 cytochrome c
102893036 cytochrome c, testis-specific-like
102897687 APAF1; apoptotic protease-activating factor 1
102878565 CASP9; caspase-9
102897289 CASP3; caspase-3
102895524 MYC; myc proto-oncogene protein
102881979 MAX; protein max isoform X2
102877831 ZBTB17; zinc finger and BTB domain-containing protein 17
102893142 CDKN2B; cyclin-dependent kinase 4 inhibitor B
102894222 CDK4; cyclin-dependent kinase 4
102896272 CDK6; cyclin-dependent kinase 6
102885330 CCND1; G1/S-specific cyclin-D1
102894196 CKS1B; cyclin-dependent kinases regulatory subunit 1
102879697 CKS2; cyclin-dependent kinases regulatory subunit 2
102880695 SKP2; S-phase kinase-associated protein 2
102880085 CDKN1B; cyclin-dependent kinase inhibitor 1B
102893397 CDK2; cyclin-dependent kinase 2 isoform X1
102882411 CCNE2; G1/S-specific cyclin-E2 isoform X1
102882260 CCNE1; LOW QUALITY PROTEIN: G1/S-specific cyclin-E1
102893019 RB1; retinoblastoma-associated protein
102895276 E2F1; transcription factor E2F1
102884459 E2F2; transcription factor E2F2 isoform X1
102887239 E2F3; transcription factor E2F3 isoform X1
102879139 COL4A3; LOW QUALITY PROTEIN: collagen alpha-3(IV) chain
102879385 COL4A4; collagen alpha-4(IV) chain
102898331 COL4A1; LOW QUALITY PROTEIN: collagen alpha-1(IV) chain
102891781 COL4A5; collagen alpha-5(IV) chain isoform X1
102895248 COL4A6; collagen alpha-6(IV) chain
102898083 COL4A2; collagen alpha-2(IV) chain
102894718 LAMA2; laminin subunit alpha-2 isoform X1
102884860 LAMA1; laminin subunit alpha-1 isoform X1
102897225 LAMA3; laminin subunit alpha-3 isoform X6
102892706 LAMA5; laminin subunit alpha-5
102877962 LAMA4; laminin subunit alpha-4
102881611 LAMB1; laminin subunit beta-1 isoform X1
102889392 LAMB2; laminin subunit beta-2 isoform X1
102896504 LAMB3; laminin subunit beta-3
102896150 LAMB4; laminin subunit beta-4
102885413 LAMC1; laminin subunit gamma-1
102892078 LAMC2; laminin subunit gamma-2
102881476 LAMC3; laminin subunit gamma-3
102891509 FN1; fibronectin isoform X1
102897185 ITGA2; integrin alpha-2 isoform X1
102883900 ITGA2B; integrin alpha-IIb
102884713 ITGA3; integrin alpha-3 isoform X1
102883425 ITGA6; integrin alpha-6 isoform X1
102895440 ITGAV; integrin alpha-V
102886785 ITGB1; integrin beta-1
102898998 PTK2; focal adhesion kinase 1
102889227 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
102880320 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
102889576 PIK3CD; LOW QUALITY PROTEIN: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
102879163 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1
102891637 phosphatidylinositol 3-kinase regulatory subunit gamma isoform X3
102879453 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
102881949 PTEN; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X1
102885144 AKT1; RAC-alpha serine/threonine-protein kinase isoform X1
102879337 AKT3; RAC-gamma serine/threonine-protein kinase isoform X1
102898305 AKT2; LOW QUALITY PROTEIN: RAC-beta serine/threonine-protein kinase
102879469 CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
102893261 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1
102880203 IKBKG; NF-kappa-B essential modulator isoform X1
102891056 NFKBIA; NF-kappa-B inhibitor alpha
102880692 NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1
102878395 RELA; transcription factor p65
102884388 baculoviral IAP repeat-containing protein 3
102884651 BIRC2; baculoviral IAP repeat-containing protein 2 isoform X1
102885349 XIAP; E3 ubiquitin-protein ligase XIAP
102889019 BIRC7; LOW QUALITY PROTEIN: baculoviral IAP repeat-containing protein 7
102887704 BCL2L1; bcl-2-like protein 1
102894412 TRAF1; TNF receptor-associated factor 1
102889343 TRAF2; TNF receptor-associated factor 2 isoform X1
102881091 TRAF3; TNF receptor-associated factor 3
102896659 TRAF4; TNF receptor-associated factor 4 isoform X1
102879730 TRAF5; TNF receptor-associated factor 5 isoform X1
102886476 TRAF6; TNF receptor-associated factor 6 isoform X1
102886561 PTGS2; prostaglandin G/H synthase 2
102878456 NOS2; nitric oxide synthase, inducible
|
K01522 FHIT; bis(5'-adenosyl)-triphosphatase [EC:3.6.1.29]
K08528 RARB; retinoic acid receptor beta
K08524 RXRA; retinoid X receptor alpha
K08525 RXRB; retinoid X receptor beta
K08526 RXRG; retinoid X receptor gamma
K04451 TP53; tumor protein p53
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K02161 BCL2; apoptosis regulator Bcl-2
K08738 CYC; cytochrome c
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04377 MYC; Myc proto-oncogene protein
K04453 MAX; Max protein
K10500 ZBTB17; zinc finger and BTB domain-containing protein 17
K04685 CDKN2B; cyclin-dependent kinase inhibitor 2B
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K04503 CCND1; G1/S-specific cyclin-D1
K02219 CKS1; cyclin-dependent kinase regulatory subunit CKS1
K02219 CKS1; cyclin-dependent kinase regulatory subunit CKS1
K03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K05637 LAMA1_2; laminin, alpha 1/2
K05637 LAMA1_2; laminin, alpha 1/2
K06240 LAMA3_5; laminin, alpha 3/5
K06240 LAMA3_5; laminin, alpha 3/5
K06241 LAMA4; laminin, alpha 4
K05636 LAMB1; laminin, beta 1
K06243 LAMB2; laminin, beta 2
K06244 LAMB3; laminin, beta 3
K06245 LAMB4; laminin, beta 4
K05635 LAMC1; laminin, gamma 1
K06246 LAMC2; laminin, gamma 2
K06247 LAMC3; laminin, gamma 3
K05717 FN1; fibronectin 1
K06481 ITGA2; integrin alpha 2
K06476 ITGA2B; integrin alpha 2B
K06482 ITGA3; integrin alpha 3
K06485 ITGA6; integrin alpha 6
K06487 ITGAV; integrin alpha V
K05719 ITGB1; integrin beta 1
K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04725 XIAP; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K16061 BIRC7_8; baculoviral IAP repeat-containing protein 7/8
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K03172 TRAF1; TNF receptor-associated factor 1
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K03174 TRAF3; TNF receptor-associated factor 3
K09848 TRAF4; TNF receptor-associated factor 4
K09849 TRAF5; TNF receptor-associated factor 5
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K11987 PTGS2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
|
05223 Non-small cell lung cancer [PATH:pale05223]
|
102883490 FHIT; bis(5'-adenosyl)-triphosphatase isoform X2
102886545 RARB; retinoic acid receptor beta
102881572 RXRA; retinoic acid receptor RXR-alpha
102888877 RXRB; retinoic acid receptor RXR-beta isoform X1
102897820 RXRG; retinoic acid receptor RXR-gamma
102896422 LOW QUALITY PROTEIN: cyclin-dependent kinase inhibitor 2A
102894222 CDK4; cyclin-dependent kinase 4
102896272 CDK6; cyclin-dependent kinase 6
102885330 CCND1; G1/S-specific cyclin-D1
102893019 RB1; retinoblastoma-associated protein
102895276 E2F1; transcription factor E2F1
102884459 E2F2; transcription factor E2F2 isoform X1
102887239 E2F3; transcription factor E2F3 isoform X1
102895590 KRAS; GTPase KRas isoform X1
102879898 RASSF1; ras association domain-containing protein 1 isoform X1
102888616 RASSF5; ras association domain-containing protein 5 isoform X2
102881410 STK4; serine/threonine-protein kinase 4 isoform X1
102889227 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
102880320 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
102889576 PIK3CD; LOW QUALITY PROTEIN: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
102879163 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1
102891637 phosphatidylinositol 3-kinase regulatory subunit gamma isoform X3
102879453 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
102896950 PDPK1; 3-phosphoinositide-dependent protein kinase 1
102885144 AKT1; RAC-alpha serine/threonine-protein kinase isoform X1
102879337 AKT3; RAC-gamma serine/threonine-protein kinase isoform X1
102898305 AKT2; LOW QUALITY PROTEIN: RAC-beta serine/threonine-protein kinase
102877892 BAD; bcl2-associated agonist of cell death isoform X1
102878565 CASP9; caspase-9
102890472 FOXO3; forkhead box protein O3
102891552 EGF; pro-epidermal growth factor isoform X1
102887662 TGFA; protransforming growth factor alpha isoform X1
102893495 EGFR; epidermal growth factor receptor
102885300 ERBB2; LOW QUALITY PROTEIN: receptor tyrosine-protein kinase erbB-2
102884470 HGF; hepatocyte growth factor isoform X1
102885990 MET; hepatocyte growth factor receptor isoform X1
102878822 GRB2; growth factor receptor-bound protein 2 isoform X1
102882462 SOS1; son of sevenless homolog 1 isoform X1
102889597 SOS2; son of sevenless homolog 2
102896270 HRAS; GTPase HRas isoform X3
102885950 NRAS; GTPase NRas isoform X2
102877877 ARAF; serine/threonine-protein kinase A-Raf isoform X2
102878393 BRAF; serine/threonine-protein kinase B-raf isoform X2
102893439 RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X1
102897122 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 isoform X1
102879034 MAP2K2; dual specificity mitogen-activated protein kinase kinase 2
102895390 MAPK1; mitogen-activated protein kinase 1
102885749 MAPK3; mitogen-activated protein kinase 3
102896228 PLCG1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1
102883128 PLCG2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
102887078 PRKCA; protein kinase C alpha type
102880663 PRKCB; protein kinase C beta type
102888961 PRKCG; protein kinase C gamma type
102889604 TP53; cellular tumor antigen p53
102894049 CDKN1A; cyclin-dependent kinase inhibitor 1
102886440 GADD45A; growth arrest and DNA damage-inducible protein GADD45 alpha
102878191 GADD45G; growth arrest and DNA damage-inducible protein GADD45 gamma
102885790 GADD45B; growth arrest and DNA damage-inducible protein GADD45 beta
102885135 BAX; apoptosis regulator BAX isoform X1
102883540 BAK1; bcl-2 homologous antagonist/killer
102879479 DDB2; DNA damage-binding protein 2 isoform X1
102890888 POLK; DNA polymerase kappa isoform X1
102891447 KIF5A; kinesin heavy chain isoform X4
102893034 KIF5C; kinesin heavy chain
102894324 KIF5B; kinesin-1 heavy chain
102878133 RET; proto-oncogene tyrosine-protein kinase receptor Ret isoform X4
102879824 EML4; echinoderm microtubule-associated protein-like 4 isoform X1
102884662 ALK; ALK tyrosine kinase receptor
102898620 JAK3; tyrosine-protein kinase JAK3
102884374 STAT3; LOW QUALITY PROTEIN: signal transducer and activator of transcription 3
102884638 signal transducer and activator of transcription 5A
102884882 signal transducer and activator of transcription 5B isoform X1
|
K01522 FHIT; bis(5'-adenosyl)-triphosphatase [EC:3.6.1.29]
K08528 RARB; retinoic acid receptor beta
K08524 RXRA; retinoid X receptor alpha
K08525 RXRB; retinoid X receptor beta
K08526 RXRG; retinoid X receptor gamma
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K04503 CCND1; G1/S-specific cyclin-D1
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K07827 KRAS; GTPase KRas
K09850 RASSF1; Ras association domain-containing protein 1
K08015 RASSF5; Ras association domain-containing protein 5
K04411 STK4; serine/threonine kinase 4
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K09408 FOXO3; forkhead box protein O3
K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K05460 HGF; hepatocyte growth factor
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04451 TP53; tumor protein p53
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K10396 KIF5; kinesin family member 5
K10396 KIF5; kinesin family member 5
K10396 KIF5; kinesin family member 5
K05126 RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
K15420 EML4; echinoderm microtubule-associated protein-like 4
K05119 ALK; anaplastic lymphoma kinase [EC:2.7.10.1]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
|
|
|
09172 Infectious disease: viral
|
05166 Human T-cell leukemia virus 1 infection [PATH:pale05166]
|
05170 Human immunodeficiency virus 1 infection [PATH:pale05170]
|
05161 Hepatitis B [PATH:pale05161]
|
05160 Hepatitis C [PATH:pale05160]
|
05171 Coronavirus disease - COVID-19 [PATH:pale05171]
|
05164 Influenza A [PATH:pale05164]
|
05162 Measles [PATH:pale05162]
|
05168 Herpes simplex virus 1 infection [PATH:pale05168]
|
05163 Human cytomegalovirus infection [PATH:pale05163]
|
05167 Kaposi sarcoma-associated herpesvirus infection [PATH:pale05167]
|
05169 Epstein-Barr virus infection [PATH:pale05169]
|
102883716 CR2; complement receptor type 2
102885256 CD19; B-lymphocyte antigen CD19
102890716 HLA class II histocompatibility antigen, DO alpha chain
102895822 HLA class II histocompatibility antigen, DQ alpha 2 chain
102896083 HLA class II histocompatibility antigen, DR alpha chain
102892493 HLA class II histocompatibility antigen, DM alpha chain isoform X3
102894815 HLA class II histocompatibility antigen, DO beta chain
102895566 HLA class II histocompatibility antigen, DQ beta 1 chain-like
102883286 LOW QUALITY PROTEIN: HLA class II histocompatibility antigen, DP beta 1 chain
102883801 rano class II histocompatibility antigen, A beta chain-like
102884055 DLA class II histocompatibility antigen, DR-1 beta chain-like
102895309 HLA class II histocompatibility antigen, DQ alpha 2 chain-like
102892903 HLA class II histocompatibility antigen, DM beta chain
102893057 TLR2; toll-like receptor 2 precursor
102890488 MYD88; myeloid differentiation primary response protein MyD88
102880867 IRAK4; interleukin-1 receptor-associated kinase 4 isoform X1
102894152 IRAK1; interleukin-1 receptor-associated kinase 1
102886476 TRAF6; TNF receptor-associated factor 6 isoform X1
102882572 TAB1; TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
102898592 TAB2; TGF-beta-activated kinase 1 and MAP3K7-binding protein 2
102882452 MAP3K7; mitogen-activated protein kinase kinase kinase 7 isoform X1
102879469 CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
102893261 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1
102880203 IKBKG; NF-kappa-B essential modulator isoform X1
102891056 NFKBIA; NF-kappa-B inhibitor alpha
102880692 NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1
102878395 RELA; transcription factor p65
102887632 TNF; tumor necrosis factor
102895746 IL6; interleukin-6
102881037 DDX58; probable ATP-dependent RNA helicase DDX58
102892463 MAVS; mitochondrial antiviral-signaling protein isoform X1
102881091 TRAF3; TNF receptor-associated factor 3
102878859 TBK1; serine/threonine-protein kinase TBK1 isoform X1
102889768 IKBKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon
102897349 IRF7; interferon regulatory factor 7
102878862 IRF3; interferon regulatory factor 3 isoform X2
102893886 interferon alpha-1
102890009 interferon alpha-4
102890512 IFNB1; interferon beta
102892040 IFNAR1; interferon alpha/beta receptor 1
102891485 IFNAR2; interferon alpha/beta receptor 2 isoform X1
102880365 JAK1; tyrosine-protein kinase JAK1 isoform X1
102895629 TYK2; non-receptor tyrosine-protein kinase TYK2 isoform X1
102886603 STAT1; signal transducer and activator of transcription 1-alpha/beta
102879640 STAT2; signal transducer and activator of transcription 2
102894320 IRF9; interferon regulatory factor 9 isoform X1
102890643 EIF2AK2; interferon-induced, double-stranded RNA-activated protein kinase
102879074 OAS1; 2'-5'-oligoadenylate synthase 1
102879322 OAS3; 2'-5'-oligoadenylate synthase 3 isoform X1
102889470 OAS2; LOW QUALITY PROTEIN: 2'-5'-oligoadenylate synthase 2
102880650 CXCL10; C-X-C motif chemokine 10
102878693 ISG15; ubiquitin-like protein ISG15
102879561 FAS; tumor necrosis factor receptor superfamily member 6 isoform X5
102892511 FADD; FAS-associated death domain protein
102878181 CASP8; caspase-8
102887379 BID; BH3-interacting domain death agonist isoform X3
102890309 BCL2L11; bcl-2-like protein 11 isoform X1
102896443 BCL2; apoptosis regulator Bcl-2
102885135 BAX; apoptosis regulator BAX isoform X1
102883540 BAK1; bcl-2 homologous antagonist/killer
102879159 cytochrome c
102893036 cytochrome c, testis-specific-like
102897687 APAF1; apoptotic protease-activating factor 1
102878565 CASP9; caspase-9
102897289 CASP3; caspase-3
102898423 T-cell receptor beta-2 chain C region
102891942 uncharacterized protein LOC102891942
102894744 CD3E; T-cell surface glycoprotein CD3 epsilon chain
102894240 CD3G; T-cell surface glycoprotein CD3 gamma chain
102894486 CD3D; T-cell surface glycoprotein CD3 delta chain
102896086 CD247; T-cell surface glycoprotein CD3 zeta chain
102889962 PSMC2; 26S proteasome regulatory subunit 7
102885558 PSMC1; 26S proteasome regulatory subunit 4
102897803 PSMC4; 26S proteasome regulatory subunit 6B
102883850 PSMC6; 26S proteasome regulatory subunit 10B
102881183 PSMC3; 26S proteasome regulatory subunit 6A
102898429 PSMC5; 26S proteasome regulatory subunit 8
102897894 PSMD2; 26S proteasome non-ATPase regulatory subunit 2
102886967 PSMD1; 26S proteasome non-ATPase regulatory subunit 1 isoform X1
102882440 PSMD3; 26S proteasome non-ATPase regulatory subunit 3
102893083 PSMD12; 26S proteasome non-ATPase regulatory subunit 12
102884968 PSMD11; 26S proteasome non-ATPase regulatory subunit 11
102881301 PSMD6; 26S proteasome non-ATPase regulatory subunit 6 isoform X1
102890061 PSMD7; 26S proteasome non-ATPase regulatory subunit 7
102887518 PSMD13; 26S proteasome non-ATPase regulatory subunit 13
102889930 PSMD4; 26S proteasome non-ATPase regulatory subunit 4 isoform X3
102887112 PSMD14; 26S proteasome non-ATPase regulatory subunit 14
102886821 PSMD8; 26S proteasome non-ATPase regulatory subunit 8 isoform X2
102886449 ADRM1; proteasomal ubiquitin receptor ADRM1 isoform X1
102881642 SEM1; 26S proteasome complex subunit SEM1
102893312 TAP1; antigen peptide transporter 1
102894050 TAP2; antigen peptide transporter 2
102886138 TAPBP; tapasin isoform X1
102879108 PDIA3; protein disulfide-isomerase A3
102881831 CALR; calreticulin
102885874 HLA class I histocompatibility antigen, B-48 alpha chain-like
102887544 H-2 class I histocompatibility antigen, Q10 alpha chain isoform X2
102898809 LOW QUALITY PROTEIN: HLA class I histocompatibility antigen, alpha chain G-like
102896885 B2M; beta-2-microglobulin
102898812 SNW1; SNW domain-containing protein 1
102886781 SIN3A; paired amphipathic helix protein Sin3a
102890938 HDAC1; histone deacetylase 1
102878536 HDAC2; histone deacetylase 2
102895738 NCOR2; nuclear receptor corepressor 2
102885308 SAP30; histone deacetylase complex subunit SAP30
102898396 SAP30L; histone deacetylase complex subunit SAP30L
102886690 CIR1; corepressor interacting with RBPJ 1
102882176 RBPJL; recombining binding protein suppressor of hairless-like protein isoform X1
102898780 RBPJ; recombining binding protein suppressor of hairless isoform X1
102890128 HES1; transcription factor HES-1
102893918 FCER2; low affinity immunoglobulin epsilon Fc receptor
102885137 RUNX3; runt-related transcription factor 3
102895524 MYC; myc proto-oncogene protein
102897683 USP7; ubiquitin carboxyl-terminal hydrolase 7
102884281 MDM2; E3 ubiquitin-protein ligase Mdm2
102889604 TP53; cellular tumor antigen p53
102894049 CDKN1A; cyclin-dependent kinase inhibitor 1
102886440 GADD45A; growth arrest and DNA damage-inducible protein GADD45 alpha
102878191 GADD45G; growth arrest and DNA damage-inducible protein GADD45 gamma
102885790 GADD45B; growth arrest and DNA damage-inducible protein GADD45 beta
102879479 DDB2; DNA damage-binding protein 2 isoform X1
102890888 POLK; DNA polymerase kappa isoform X1
102879730 TRAF5; TNF receptor-associated factor 5 isoform X1
102889227 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
102880320 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
102889576 PIK3CD; LOW QUALITY PROTEIN: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
102879163 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1
102891637 phosphatidylinositol 3-kinase regulatory subunit gamma isoform X3
102879453 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
102885144 AKT1; RAC-alpha serine/threonine-protein kinase isoform X1
102879337 AKT3; RAC-gamma serine/threonine-protein kinase isoform X1
102898305 AKT2; LOW QUALITY PROTEIN: RAC-beta serine/threonine-protein kinase
102897751 MAP3K14; mitogen-activated protein kinase kinase kinase 14
102886161 RELB; transcription factor RelB
102894780 NFKB2; nuclear factor NF-kappa-B p100 subunit isoform X1
102893401 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
102881802 NFKBIB; NF-kappa-B inhibitor beta
102887733 NFKBIE; NF-kappa-B inhibitor epsilon
102894945 MAP2K4; dual specificity mitogen-activated protein kinase kinase 4 isoform X3
102892533 MAP2K7; dual specificity mitogen-activated protein kinase kinase 7
102885064 MAPK10; mitogen-activated protein kinase 10 isoform X5
102890689 MAPK9; mitogen-activated protein kinase 9 isoform X1
102892777 MAPK8; mitogen-activated protein kinase 8 isoform X1
102889343 TRAF2; TNF receptor-associated factor 2 isoform X1
102885162 RIPK1; receptor-interacting serine/threonine-protein kinase 1
102886389 MAP2K3; dual specificity mitogen-activated protein kinase kinase 3 isoform X1
102888822 MAP2K6; dual specificity mitogen-activated protein kinase kinase 6
102895900 MAPK14; mitogen-activated protein kinase 14 isoform X1
102888602 MAPK11; mitogen-activated protein kinase 11 isoform X1
102888845 MAPK12; mitogen-activated protein kinase 12 isoform X1
102877720 MAPK13; mitogen-activated protein kinase 13
102896121 JUN; transcription factor AP-1
102890548 ENTPD1; ectonucleoside triphosphate diphosphohydrolase 1
102897950 ENTPD8; ectonucleoside triphosphate diphosphohydrolase 8 isoform X2
102879249 ENTPD3; LOW QUALITY PROTEIN: ectonucleoside triphosphate diphosphohydrolase 3
102890443 CD40; tumor necrosis factor receptor superfamily member 5 isoform X1
102893320 CD44; CD44 antigen
102879417 ITGAL; integrin alpha-L isoform X1
102886192 CD58; lymphocyte function-associated antigen 3
102897326 ICAM1; intercellular adhesion molecule 1
102879983 VIM; vimentin
102887009 TNFAIP3; tumor necrosis factor alpha-induced protein 3
102898620 JAK3; tyrosine-protein kinase JAK3
102884374 STAT3; LOW QUALITY PROTEIN: signal transducer and activator of transcription 3
102880204 LYN; tyrosine-protein kinase Lyn isoform X1
102888426 SYK; tyrosine-protein kinase SYK isoform X1
102877765 NEDD4; E3 ubiquitin-protein ligase NEDD4 isoform X5
102897644 RAC1; ras-related C3 botulinum toxin substrate 1 isoform X1
102892050 immunoglobulin heavy variable 1-46
102878592 BTK; tyrosine-protein kinase BTK
102889376 BLNK; B-cell linker protein
102883128 PLCG2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
102880695 SKP2; S-phase kinase-associated protein 2
102880085 CDKN1B; cyclin-dependent kinase inhibitor 1B
102885330 CCND1; G1/S-specific cyclin-D1
102892640 CCND2; G1/S-specific cyclin-D2
102881884 CCND3; G1/S-specific cyclin-D3
102894222 CDK4; cyclin-dependent kinase 4
102896272 CDK6; cyclin-dependent kinase 6
102890664 CCNA1; cyclin-A1
102894080 CCNA2; cyclin-A2
102882411 CCNE2; G1/S-specific cyclin-E2 isoform X1
102882260 CCNE1; LOW QUALITY PROTEIN: G1/S-specific cyclin-E1
102893397 CDK2; cyclin-dependent kinase 2 isoform X1
102893019 RB1; retinoblastoma-associated protein
102895276 E2F1; transcription factor E2F1
102884459 E2F2; transcription factor E2F2 isoform X1
102887239 E2F3; transcription factor E2F3 isoform X1
|
K04012 CR2; complement receptor type 2
K06465 CD19; B-lymphocyte antigen CD19
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K10159 TLR2; toll-like receptor 2
K04729 MYD88; myeloid differentiation primary response protein MyD88
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K04403 MAP3K7IP1; TAK1-binding protein 1
K04404 MAP3K7IP2; TAK1-binding protein 2
K04427 MAP3K7; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K03156 TNF; tumor necrosis factor superfamily, member 2
K05405 IL6; interleukin 6
K12646 RIGI; ATP-dependent RNA helicase DDX58 [EC:5.6.2.6]
K12648 MAVS; mitochondrial antiviral-signaling protein
K03174 TRAF3; TNF receptor-associated factor 3
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K07211 IKBKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
K09447 IRF7; interferon regulatory factor 7
K05411 IRF3; interferon regulatory factor 3
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K04693 IRF9; interferon regulatory factor 9
K16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
K14216 OAS; 2'-5'-oligoadenylate synthetase [EC:2.7.7.84]
K14216 OAS; 2'-5'-oligoadenylate synthetase [EC:2.7.7.84]
K14216 OAS; 2'-5'-oligoadenylate synthetase [EC:2.7.7.84]
K12671 CXCL10; C-X-C motif chemokine 10
K12159 ISG15; ubiquitin cross-reactive protein
K04390 TNFRSF6; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K16341 BCL2L11; Bcl-2-like protein 11
K02161 BCL2; apoptosis regulator Bcl-2
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K08738 CYC; cytochrome c
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K10785 TRBV; T-cell receptor beta chain V region
K10785 TRBV; T-cell receptor beta chain V region
K06451 CD3E; T-cell surface glycoprotein CD3 epsilon chain
K06452 CD3G; T-cell surface glycoprotein CD3 gamma chain
K06450 CD3D; T-cell surface glycoprotein CD3 delta chain
K06453 CD3Z; CD3Z antigen, zeta polypeptide
K03061 PSMC2; 26S proteasome regulatory subunit T1
K03062 PSMC1; 26S proteasome regulatory subunit T2
K03063 PSMC4; 26S proteasome regulatory subunit T3
K03064 PSMC6; 26S proteasome regulatory subunit T4
K03065 PSMC3; 26S proteasome regulatory subunit T5
K03066 PSMC5; 26S proteasome regulatory subunit T6
K03028 PSMD2; 26S proteasome regulatory subunit N1
K03032 PSMD1; 26S proteasome regulatory subunit N2
K03033 PSMD3; 26S proteasome regulatory subunit N3
K03035 PSMD12; 26S proteasome regulatory subunit N5
K03036 PSMD11; 26S proteasome regulatory subunit N6
K03037 PSMD6; 26S proteasome regulatory subunit N7
K03038 PSMD7; 26S proteasome regulatory subunit N8
K03039 PSMD13; 26S proteasome regulatory subunit N9
K03029 PSMD4; 26S proteasome regulatory subunit N10
K03030 PSMD14; 26S proteasome regulatory subunit N11
K03031 PSMD8; 26S proteasome regulatory subunit N12
K06691 RPN13; 26S proteasome regulatory subunit N13
K10881 SHFM1; 26 proteasome complex subunit DSS1
K05653 ABCB2; ATP-binding cassette, subfamily B (MDR/TAP), member 2 [EC:7.4.2.14]
K05654 ABCB3; ATP-binding cassette, subfamily B (MDR/TAP), member 3 [EC:7.4.2.14]
K08058 TAPBP; TAP binding protein (tapasin)
K08056 PDIA3; protein disulfide-isomerase A3 [EC:5.3.4.1]
K08057 CALR; calreticulin
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K08055 B2M; beta-2-microglobulin
K06063 SNW1; SNW domain-containing protein 1
K11644 SIN3A; paired amphipathic helix protein Sin3a
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K06065 NCOR2; nuclear receptor co-repressor 2
K19202 SAP30; histone deacetylase complex subunit SAP30
K19202 SAP30; histone deacetylase complex subunit SAP30
K06066 CIR; CBF1 interacting corepressor
K06053 RBPSUH; recombining binding protein suppressor of hairless
K06053 RBPSUH; recombining binding protein suppressor of hairless
K06054 HES1; hairy and enhancer of split 1
K06468 FCER2; low affinity immunoglobulin epsilon Fc receptor
K09279 RUNX3; runt-related transcription factor 3
K04377 MYC; Myc proto-oncogene protein
K11838 USP7; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53; tumor protein p53
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K09849 TRAF5; TNF receptor-associated factor 5
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04466 MAP3K14; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
K09253 RELB; transcription factor RelB
K04469 NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K02581 NFKBIB; NF-kappa-B inhibitor beta
K05872 NFKBIE; NF-kappa-B inhibitor epsilon
K04430 MAP2K4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K02861 RIPK1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
K04432 MAP2K3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K01510 ENTPD1_3_8; apyrase [EC:3.6.1.5]
K01510 ENTPD1_3_8; apyrase [EC:3.6.1.5]
K01510 ENTPD1_3_8; apyrase [EC:3.6.1.5]
K03160 TNFRSF5; tumor necrosis factor receptor superfamily member 5
K06256 CD44; CD44 antigen
K05718 ITGAL; integrin alpha L
K06492 CD58; CD58 antigen
K06490 ICAM1; intercellular adhesion molecule 1
K07606 VIM; vimentin
K11859 TNFAIP3; tumor necrosis factor, alpha-induced protein 3 [EC:3.4.19.12]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K05854 LYN; tyrosine-protein kinase Lyn [EC:2.7.10.2]
K05855 SYK; spleen tyrosine kinase [EC:2.7.10.2]
K10591 NEDD4; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K06856 IGH; immunoglobulin heavy chain
K07370 BTK; Bruton agammaglobulinemia tyrosine kinase [EC:2.7.10.2]
K07371 BLNK; B-cell linker protein
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06627 CCNA; cyclin-A
K06627 CCNA; cyclin-A
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
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05165 Human papillomavirus infection [PATH:pale05165]
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09171 Infectious disease: bacterial
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09174 Infectious disease: parasitic
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09163 Immune disease
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09164 Neurodegenerative disease
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09165 Substance dependence
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09166 Cardiovascular disease
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09167 Endocrine and metabolic disease
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09175 Drug resistance: antimicrobial
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09176 Drug resistance: antineoplastic
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09180 Brite Hierarchies
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09181 Protein families: metabolism
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09182 Protein families: genetic information processing
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03000 Transcription factors [BR:pale03000]
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03021 Transcription machinery [BR:pale03021]
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03019 Messenger RNA biogenesis [BR:pale03019]
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03041 Spliceosome [BR:pale03041]
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03011 Ribosome [BR:pale03011]
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03009 Ribosome biogenesis [BR:pale03009]
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03016 Transfer RNA biogenesis [BR:pale03016]
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03012 Translation factors [BR:pale03012]
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03110 Chaperones and folding catalysts [BR:pale03110]
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04131 Membrane trafficking [BR:pale04131]
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04121 Ubiquitin system [BR:pale04121]
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03051 Proteasome [BR:pale03051]
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03032 DNA replication proteins [BR:pale03032]
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03036 Chromosome and associated proteins [BR:pale03036]
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03400 DNA repair and recombination proteins [BR:pale03400]
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102888658 MGMT; methylated-DNA--protein-cysteine methyltransferase
102887953 ALKBH2; DNA oxidative demethylase ALKBH2
102889640 ALKBH3; alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 isoform X2
102887705 UNG; uracil-DNA glycosylase
102885996 CCNO; cyclin-O
102888665 TDG; G/T mismatch-specific thymine DNA glycosylase isoform X2
102881650 MPG; DNA-3-methyladenine glycosylase isoform X2
102889610 SMUG1; single-strand selective monofunctional uracil DNA glycosylase isoform X1
102888194 MUTYH; adenine DNA glycosylase isoform X2
102894925 MBD4; methyl-CpG-binding domain protein 4 isoform X2
102884174 OGG1; N-glycosylase/DNA lyase isoform X2
102887454 NEIL1; endonuclease 8-like 1 isoform X1
102882777 NEIL2; endonuclease 8-like 2
102894583 NEIL3; endonuclease 8-like 3 isoform X1
102880592 NTHL1; endonuclease III-like protein 1 isoform X2
102897846 APEX1; DNA-(apurinic or apyrimidinic site) lyase isoform X1
102898078 APEX2; DNA-(apurinic or apyrimidinic site) lyase 2
102896397 POLD1; DNA polymerase delta catalytic subunit
102884073 POLD2; DNA polymerase delta subunit 2
102895310 POLD3; DNA polymerase delta subunit 3
102893003 POLD4; DNA polymerase delta subunit 4
102892506 POLE; DNA polymerase epsilon catalytic subunit A isoform X1
102883769 POLE2; DNA polymerase epsilon subunit 2
102880775 POLE3; DNA polymerase epsilon subunit 3
102896323 POLE4; DNA polymerase epsilon subunit 4 isoform X1
102890018 PCNA; proliferating cell nuclear antigen
102894568 FEN1; flap endonuclease 1
102888944 LIG1; LOW QUALITY PROTEIN: DNA ligase 1
102893018 POLB; DNA polymerase beta
102885428 XRCC1; DNA repair protein XRCC1
102896329 LIG3; DNA ligase 3
102885143 TDP1; tyrosyl-DNA phosphodiesterase 1 isoform X2
102880269 APTX; aprataxin isoform X1
102893075 APLF; aprataxin and PNK-like factor
102898132 PNKP; bifunctional polynucleotide phosphatase/kinase
102882684 HMGB1; high mobility group protein B1
102894809 POLL; DNA polymerase lambda isoform X1
102882722 PARP1; poly [ADP-ribose] polymerase 1
102895597 PARP4; poly [ADP-ribose] polymerase 4
102896370 PARP2; poly [ADP-ribose] polymerase 2
102884230 PARP3; poly [ADP-ribose] polymerase 3
102895308 XPC; DNA repair protein complementing XP-C cells isoform X1
102888054 RAD23B; UV excision repair protein RAD23 homolog B isoform X1
102882080 RAD23A; UV excision repair protein RAD23 homolog A
102879702 CETN2; centrin-2
102893437 RBX1; E3 ubiquitin-protein ligase RBX1
102892859 CUL4B; cullin-4B isoform X1
102883045 CUL4A; cullin-4A
102897514 DDB1; DNA damage-binding protein 1
102879479 DDB2; DNA damage-binding protein 2 isoform X1
102885614 POLR2A; DNA-directed RNA polymerase II subunit RPB1 isoform X1
102879872 POLR2B; DNA-directed RNA polymerase II subunit RPB2
102890873 POLR2C; DNA-directed RNA polymerase II subunit RPB3
102882561 POLR2D; DNA-directed RNA polymerase II subunit RPB4
102877935 POLR2E; DNA-directed RNA polymerases I, II, and III subunit RPABC1 isoform X1
102881812 POLR2F; DNA-directed RNA polymerases I, II, and III subunit RPABC2 isoform X1
102887999 POLR2G; DNA-directed RNA polymerase II subunit RPB7 isoform X2
102878376 POLR2H; DNA-directed RNA polymerases I, II, and III subunit RPABC3
102892810 POLR2I; DNA-directed RNA polymerase II subunit RPB9
102878984 POLR2L; DNA-directed RNA polymerases I, II, and III subunit RPABC5
102897120 POLR2J; DNA-directed RNA polymerase II subunit RPB11-a
102894671 POLR2K; DNA-directed RNA polymerases I, II, and III subunit RPABC4
102878531 ERCC8; DNA excision repair protein ERCC-8 isoform X1
102895255 ERCC6; DNA excision repair protein ERCC-6 isoform X1
102878840 UVSSA; UV-stimulated scaffold protein A
102884884 ELOF1; transcription elongation factor 1 homolog isoform X1
102881014 ERCC3; general transcription and DNA repair factor IIH helicase subunit XPB
102891047 ERCC2; general transcription and DNA repair factor IIH helicase subunit XPD
102887484 GTF2H1; general transcription factor IIH subunit 1 isoform X2
102883057 GTF2H2; general transcription factor IIH subunit 2
102896263 GTF2H3; general transcription factor IIH subunit 3 isoform X2
102883568 GTF2H4; general transcription factor IIH subunit 4
102896540 GTF2H5; general transcription factor IIH subunit 5 isoform X1
102880932 CDK7; cyclin-dependent kinase 7 isoform X1
102883058 CCNH; cyclin-H isoform X2
102896029 MNAT1; CDK-activating kinase assembly factor MAT1
102889870 RPA1; replication protein A 70 kDa DNA-binding subunit
102883783 RPA2; replication protein A 32 kDa subunit
102884493 RPA3; replication protein A 14 kDa subunit isoform X1
102878725 RPA4; LOW QUALITY PROTEIN: replication protein A 30 kDa subunit
102883387 XPA; DNA repair protein complementing XP-A cells isoform X1
102891932 ERCC1; DNA excision repair protein ERCC-1 isoform X2
102881542 ERCC4; LOW QUALITY PROTEIN: DNA repair endonuclease XPF
102890150 DNA repair protein complementing XP-G cells isoform X4
102886470 MMS19; MMS19 nucleotide excision repair protein homolog isoform X1
102879889 CUL3; cullin-3
102897835 CUL5; cullin-5 isoform X1
102895455 ELOC; elongin-C
102895498 ELOB; elongin-B
102886128 ELOA; elongin-A
102898097 UBAP2; LOW QUALITY PROTEIN: ubiquitin-associated protein 2
102896645 UBAP2L; ubiquitin-associated protein 2-like isoform X10
102893728 MSH2; DNA mismatch repair protein Msh2 isoform X3
102878992 MSH3; DNA mismatch repair protein Msh3 isoform X1
102892999 MSH6; DNA mismatch repair protein Msh6
102884442 PMS1; PMS1 protein homolog 1 isoform X1
102898392 MLH1; DNA mismatch repair protein Mlh1 isoform X1
102879718 PMS2; mismatch repair endonuclease PMS2 isoform X1
102890288 MLH3; DNA mismatch repair protein Mlh3 isoform X1
102892618 RFC1; replication factor C subunit 1 isoform X3
102886215 RFC4; replication factor C subunit 4 isoform X2
102888919 RFC2; replication factor C subunit 2 isoform X1
102885071 RFC5; replication factor C subunit 5
102891620 RFC3; replication factor C subunit 3 isoform X1
102880463 EXO1; exonuclease 1 isoform X1
102881924 WDR76; WD repeat-containing protein 76 isoform X1
102878053 MRE11; double-strand break repair protein MRE11 isoform X1
102890531 RAD50; DNA repair protein RAD50 isoform X1
102881755 NBN; nibrin isoform X1
102895982 BRCA1; breast cancer type 1 susceptibility protein isoform X1
102893717 BARD1; LOW QUALITY PROTEIN: BRCA1-associated RING domain protein 1
102888310 ABRAXAS1; BRCA1-A complex subunit Abraxas 1 isoform X3
102878605 UIMC1; BRCA1-A complex subunit RAP80 isoform X2
102894026 BABAM1; BRISC and BRCA1-A complex member 1 isoform X1
102880922 BABAM2; BRISC and BRCA1-A complex member 2
102897805 BRCC3; lys-63-specific deubiquitinase BRCC36 isoform X2
102890464 BRIP1; Fanconi anemia group J protein
102887896 TOPBP1; DNA topoisomerase 2-binding protein 1 isoform X1
102898606 RBBP8; DNA endonuclease RBBP8 isoform X1
102896802 BRCA2; breast cancer type 2 susceptibility protein
102895844 PALB2; partner and localizer of BRCA2 isoform X1
102894016 RAD51; DNA repair protein RAD51 homolog 1
102895090 RAD51B; DNA repair protein RAD51 homolog 2 isoform X6
102885802 RAD51C; DNA repair protein RAD51 homolog 3 isoform X3
102882022 RAD51D; DNA repair protein RAD51 homolog 4 isoform X3
102888362 XRCC2; DNA repair protein XRCC2
102887560 XRCC3; LOW QUALITY PROTEIN: DNA repair protein XRCC3
102880900 RAD52; DNA repair protein RAD52 homolog isoform X1
102898831 RDM1; RAD52 motif-containing protein 1 isoform X1
102892784 RAD54L; DNA repair and recombination protein RAD54-like isoform X2
102883044 RAD54L2; helicase ARIP4 isoform X1
102891752 RAD54B; DNA repair and recombination protein RAD54B isoform X2
102890323 RECQL; ATP-dependent DNA helicase Q1 isoform X2
102886512 WRN; Werner syndrome ATP-dependent helicase
102888215 BLM; Bloom syndrome protein isoform X1
102887502 RECQL4; ATP-dependent DNA helicase Q4
102898994 RECQL5; ATP-dependent DNA helicase Q5
102880328 TOP3B; DNA topoisomerase 3-beta-1 isoform X2
102878631 TOP3A; DNA topoisomerase 3-alpha isoform X1
102883483 RMI1; recQ-mediated genome instability protein 1
102891141 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit isoform X1
102890758 PPP4R1; serine/threonine-protein phosphatase 4 regulatory subunit 1 isoform X1
102882836 LOW QUALITY PROTEIN: serine/threonine-protein phosphatase 4 regulatory subunit 1-like
102897115 PPP4R2; serine/threonine-protein phosphatase 4 regulatory subunit 2 isoform X1
102886393 PPP4R3B; serine/threonine-protein phosphatase 4 regulatory subunit 3B isoform X1
102886799 PPP4R3A; serine/threonine-protein phosphatase 4 regulatory subunit 3A isoform X1
102895206 serine/threonine-protein phosphatase 4 regulatory subunit 3B
102893476 PPP4R4; serine/threonine-protein phosphatase 4 regulatory subunit 4 isoform X1
102886819 AP5B1; AP-5 complex subunit beta-1
102896468 AP5M1; AP-5 complex subunit mu-1
102892877 AP5S1; AP-5 complex subunit sigma-1
102878794 AP5Z1; AP-5 complex subunit zeta-1
102888758 SMC5; structural maintenance of chromosomes protein 5 isoform X2
102878639 SMC6; structural maintenance of chromosomes protein 6
102898420 FAM84A; protein FAM84A
102893085 NSMCE1; non-structural maintenance of chromosomes element 1 homolog isoform X1
102894409 NSMCE2; E3 SUMO-protein ligase NSE2 isoform X1
102891587 NSMCE3; non-structural maintenance of chromosomes element 3 homolog
102884411 NSMCE4A; non-structural maintenance of chromosomes element 4 homolog A
102887259 EID3; EP300-interacting inhibitor of differentiation 3
102888087 SLF1; SMC5-SMC6 complex localization factor protein 1 isoform X1
102897645 SLF2; SMC5-SMC6 complex localization factor protein 2 isoform X1
102887468 EME1; crossover junction endonuclease EME1 isoform X1
102878659 EME2; probable crossover junction endonuclease EME2 isoform X1
102888910 EXD2; exonuclease 3'-5' domain-containing protein 2
102885920 MUS81; crossover junction endonuclease MUS81 isoform X7
102881642 SEM1; 26S proteasome complex subunit SEM1
102898029 SWI5; DNA repair protein SWI5 homolog
102887616 SFR1; swi5-dependent recombination DNA repair protein 1 homolog
102889663 SLX1A; structure-specific endonuclease subunit SLX1 isoform X1
102887590 SLX4; LOW QUALITY PROTEIN: structure-specific endonuclease subunit SLX4
102878891 GEN1; flap endonuclease GEN homolog 1 isoform X1
102897612 SPG11; spatacsin isoform X2
102886831 ZFYVE26; zinc finger FYVE domain-containing protein 26 isoform X1
102891656 RAD51AP1; RAD51-associated protein 1 isoform X1
102889615 MORF4L1; mortality factor 4-like protein 1
102889853 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 isoform X1
102898253 FIGNL1; fidgetin-like protein 1 isoform X2
102896063 SPIDR; LOW QUALITY PROTEIN: DNA repair-scaffolding protein
102893433 FAM84B; protein FAM84B
102888913 BRAT1; BRCA1-associated ATM activator 1 isoform X1
102895189 CUNH21orf2; protein C21orf2 isoform X2
102881073 HDGFL2; hepatoma-derived growth factor-related protein 2
102895073 ZSWIM7; LOW QUALITY PROTEIN: zinc finger SWIM domain-containing protein 7
102880984 SWSAP1; ATPase SWSAP1
102878382 EMSY; BRCA2-interacting transcriptional repressor EMSY isoform X8
102892688 HSF2BP; heat shock factor 2-binding protein isoform X3
102878540 MMS22L; protein MMS22-like isoform X1
102891290 TONSL; tonsoku-like protein
102890513 BOD1L1; biorientation of chromosomes in cell division protein 1-like 1 isoform X1
102890739 PARPBP; PCNA-interacting partner isoform X1
102890254 XRCC6; X-ray repair cross-complementing protein 6
102890386 XRCC5; X-ray repair cross-complementing protein 5
102895801 PRKDC; DNA-dependent protein kinase catalytic subunit isoform X1
102888401 LIG4; DNA ligase 4 isoform X1
102881460 XRCC4; DNA repair protein XRCC4 isoform X1
102882950 NHEJ1; non-homologous end-joining factor 1
102883214 POLM; DNA-directed DNA/RNA polymerase mu isoform X3
102888799 DNTT; DNA nucleotidylexotransferase isoform X1
102898649 DCLRE1C; protein artemis isoform X1
102896374 TDP2; tyrosyl-DNA phosphodiesterase 2 isoform X1
102883943 SMCHD1; structural maintenance of chromosomes flexible hinge domain-containing protein 1
102878523 PWWP domain-containing protein MUM1L1
102878943 PWWP domain-containing protein MUM1 isoform X1
102894855 MUM1L1; PWWP domain-containing protein MUM1L1
102890096 PAXX; protein PAXX isoform X2
102885422 CYREN; cell cycle regulator of non-homologous end joining
102881719 JMJD8; jmjC domain-containing protein 8 isoform X1
102888855 SHLD1; uncharacterized protein C20orf196 homolog
102885588 SHLD2; protein FAM35A isoform X1
102884278 FANCA; Fanconi anemia group A protein isoform X2
102891129 FANCB; Fanconi anemia group B protein
102881661 FANCC; Fanconi anemia group C protein isoform X5
102898238 FANCE; Fanconi anemia group E protein isoform X1
102892576 FANCF; Fanconi anemia group F protein
102890585 FANCG; Fanconi anemia group G protein
102884487 FANCL; E3 ubiquitin-protein ligase FANCL
102886782 FANCM; Fanconi anemia group M protein
102891915 FAAP24; Fanconi anemia core complex-associated protein 24
102890885 FAAP100; Fanconi anemia core complex-associated protein 100
102890128 HES1; transcription factor HES-1
102886828 CENPS; centromere protein S
107195713 CENPX; centromere protein X
102879480 UBE2T; ubiquitin-conjugating enzyme E2 T isoform X2
102887690 FANCD2; Fanconi anemia group D2 protein isoform X1
102882939 FANCI; Fanconi anemia group I protein isoform X2
102890629 FAN1; fanconi-associated nuclease 1
112475776 fanconi-associated nuclease 1-like isoform X1
102879418 TELO2; telomere length regulation protein TEL2 homolog isoform X1
102898461 USP1; ubiquitin carboxyl-terminal hydrolase 1 isoform X1
102895486 WDR48; WD repeat-containing protein 48
102894507 PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit
102888588 PPP6R1; serine/threonine-protein phosphatase 6 regulatory subunit 1 isoform X1
102881569 PPP6R2; serine/threonine-protein phosphatase 6 regulatory subunit 2 isoform X1
102886572 PPP6R3; serine/threonine-protein phosphatase 6 regulatory subunit 3 isoform X1
102894460 ANKRD28; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X3
102890109 ANKRD44; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B isoform X1
102898741 ANKRD52; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C
102891032 RNF8; E3 ubiquitin-protein ligase RNF8 isoform X5
102885224 RNF168; E3 ubiquitin-protein ligase RNF168
102882290 RNF169; E3 ubiquitin-protein ligase RNF169
102887399 E3 ubiquitin-protein ligase HERC2
102889856 WRAP53; telomerase Cajal body protein 1 isoform X1
102895425 TPRN; taperin
102888190 ZCWPW1; zinc finger CW-type PWWP domain protein 1 isoform X2
102882919 WDR70; WD repeat-containing protein 70
102891912 POLH; DNA polymerase eta isoform X1
102894090 POLI; DNA polymerase iota
102890888 POLK; DNA polymerase kappa isoform X1
102890504 REV1; DNA repair protein REV1 isoform X5
102896156 REV3L; DNA polymerase zeta catalytic subunit isoform X2
102898460 POLN; DNA polymerase nu
102895543 UBE2A; ubiquitin-conjugating enzyme E2 A
102884788 UBE2B; ubiquitin-conjugating enzyme E2 B
102879933 RAD18; E3 ubiquitin-protein ligase RAD18 isoform X1
102896367 HLTF; helicase-like transcription factor isoform X1
102896128 UBE2V1; ubiquitin-conjugating enzyme E2 variant 1 isoform X1
102894535 UBE2V2; ubiquitin-conjugating enzyme E2 variant 2 isoform X1
102888783 UBE2N; ubiquitin-conjugating enzyme E2 N
102886851 SPRTN; sprT-like domain-containing protein Spartan isoform X1
102897745 GCNA; acidic repeat-containing protein isoform X1
102892509 RAD9A; cell cycle checkpoint control protein RAD9A isoform X1
102879901 RAD9B; cell cycle checkpoint control protein RAD9B
102887750 HUS1; checkpoint protein HUS1 isoform X3
102898708 HUS1B; LOW QUALITY PROTEIN: checkpoint protein HUS1B
102888105 RAD1; cell cycle checkpoint protein RAD1
102881970 RAD17; cell cycle checkpoint protein RAD17 isoform X2
102879896 TIMELESS; protein timeless homolog isoform X1
102897374 TIPIN; TIMELESS-interacting protein
102880053 CLSPN; claspin isoform X1
102892465 TTI1; TELO2-interacting protein 1 homolog
102884339 TTI2; TELO2-interacting protein 2
102885881 BAG6; large proline-rich protein BAG6
102895670 UBL4A; ubiquitin-like protein 4A
102895100 UBL4B; ubiquitin-like protein 4B
102889829 GET4; Golgi to ER traffic protein 4 homolog
102889339 ATR; LOW QUALITY PROTEIN: serine/threonine-protein kinase ATR
102888318 ATRIP; ATR-interacting protein
102898588 ATM; serine-protein kinase ATM isoform X1
102889604 TP53; cellular tumor antigen p53
102882405 CHEK1; serine/threonine-protein kinase Chk1
102882358 CHEK2; LOW QUALITY PROTEIN: serine/threonine-protein kinase Chk2
102897196 CDC25A; M-phase inducer phosphatase 1 isoform X1
102893112 CDC25B; M-phase inducer phosphatase 2 isoform X1
102894193 CDC25C; M-phase inducer phosphatase 3 isoform X3
102880620 YWHAB; 14-3-3 protein beta/alpha
102894826 YWHAQ; 14-3-3 protein theta
102893263 YWHAZ; 14-3-3 protein zeta/delta
102895426 YWHAG; 14-3-3 protein gamma
102878861 YWHAH; 14-3-3 protein eta
102885303 YWHAE; 14-3-3 protein epsilon isoform X1
102890794 NAV2; neuron navigator 2 isoform X2
102880081 WEE2; wee1-like protein kinase 2
102878200 WEE1; wee1-like protein kinase
102893856 PER1; period circadian protein homolog 1 isoform X4
102896517 PER2; LOW QUALITY PROTEIN: period circadian protein homolog 2
102885184 PER3; period circadian protein homolog 3
102881647 MDC1; mediator of DNA damage checkpoint protein 1 isoform X2
102889055 PLS3; plastin-3
102881341 AEN; apoptosis-enhancing nuclease isoform X2
102886992 PLK3; serine/threonine-protein kinase PLK3
102894766 NEK4; serine/threonine-protein kinase Nek4 isoform X2
102888550 NEK1; serine/threonine-protein kinase Nek1 isoform X2
102893235 serine/threonine-protein kinase Nek5 isoform X1
102879805 NEK10; serine/threonine-protein kinase Nek10 isoform X1
102891911 NEK11; serine/threonine-protein kinase Nek11 isoform X4
102878436 DONSON; protein downstream neighbor of Son
102886342 KANK1; KN motif and ankyrin repeat domain-containing protein 1 isoform X1
102888297 KANK2; KN motif and ankyrin repeat domain-containing protein 2
102889748 KANK3; KN motif and ankyrin repeat domain-containing protein 3
102898211 KANK4; KN motif and ankyrin repeat domain-containing protein 4
102880732 KLLN; LOW QUALITY PROTEIN: killin
102880906 SLFN11; schlafen family member 11 isoform X1
102879040 CHMP4C; charged multivesicular body protein 4c
102884816 VPS4A; vacuolar protein sorting-associated protein 4A
102896701 VPS4B; vacuolar protein sorting-associated protein 4B isoform X2
102893276 ZFYVE19; LOW QUALITY PROTEIN: abscission/NoCut checkpoint regulator
102883152 SDE2; replication stress response regulator SDE2
102885054 POLQ; DNA polymerase theta isoform X1
102882590 MYBBP1A; myb-binding protein 1A
102897941 PRIMPOL; DNA-directed primase/polymerase protein isoform X1
102883126 TREX1; three-prime repair exonuclease 1
102882649 TREX2; three prime repair exonuclease 2
102878934 DCLRE1A; DNA cross-link repair 1A protein
102883941 DCLRE1B; LOW QUALITY PROTEIN: 5' exonuclease Apollo
102878511 EXO5; exonuclease V
102892843 ENDOV; LOW QUALITY PROTEIN: endonuclease V
102886602 ZRANB3; DNA annealing helicase and endonuclease ZRANB3 isoform X3
102882181 ANKLE1; ankyrin repeat and LEM domain-containing protein 1
102888560 HELQ; helicase POLQ-like isoform X4
102881400 ERCC6L2; DNA excision repair protein ERCC-6-like 2 isoform X1
102878394 PRPF19; pre-mRNA-processing factor 19
102886976 CDC5L; cell division cycle 5-like protein
102884857 BCAS2; pre-mRNA-splicing factor SPF27
102887184 PLRG1; pleiotropic regulator 1
102892026 NUDT15; nucleotide triphosphate diphosphatase NUDT15
102895707 NUDT18; 8-oxo-dGDP phosphatase NUDT18
102890105 DUT; deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial isoform X1
102879969 RRM1; ribonucleoside-diphosphate reductase large subunit
102895346 RRM2B; ribonucleoside-diphosphate reductase subunit M2 B
102895581 uncharacterized protein LOC102895581
112469018 RRM2; ribonucleoside-diphosphate reductase subunit M2
102898494 SSBP1; single-stranded DNA-binding protein, mitochondrial isoform X2
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K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
K10859 ALKBH2; DNA oxidative demethylase [EC:1.14.11.33]
K10860 ALKBH3; mRNA N1-methyladenine demethylase [EC:1.14.11.54]
K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
K10861 UDG2; uracil-DNA glycosylase 2 [EC:3.2.2.-]
K20813 TDG; thymine-DNA glycosylase [EC:3.2.2.29]
K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
K10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-]
K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
K10801 MBD4; methyl-CpG-binding domain protein 4 [EC:3.2.2.-]
K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
K10567 NEIL1; endonuclease VIII-like 1 [EC:3.2.2.- 4.2.99.18]
K10568 NEIL2; endonuclease VIII-like 2 [EC:3.2.2.- 4.2.99.18]
K10569 NEIL3; endonuclease VIII-like 3 [EC:3.2.2.- 4.2.99.18]
K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
K10771 APEX1; AP endonuclease 1 [EC:3.1.11.2]
K10772 APEX2; AP endonuclease 2 [EC:3.1.11.2]
K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
K02328 POLD2; DNA polymerase delta subunit 2
K03504 POLD3; DNA polymerase delta subunit 3
K03505 POLD4; DNA polymerase delta subunit 4
K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
K03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]
K04802 PCNA; proliferating cell nuclear antigen
K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
K10803 XRCC1; DNA-repair protein XRCC1
K10776 LIG3; DNA ligase 3 [EC:6.5.1.1]
K10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]
K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
K13295 APLF; aprataxin and PNK-like factor [EC:3.1.-.-]
K08073 PNKP; bifunctional polynucleotide phosphatase/kinase [EC:3.1.3.32 2.7.1.78]
K10802 HMGB1; high mobility group protein B1
K03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]
K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
K10838 XPC; xeroderma pigmentosum group C-complementing protein
K10839 RAD23; UV excision repair protein RAD23
K10839 RAD23; UV excision repair protein RAD23
K10840 CETN2; centrin-2
K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
K10609 CUL4; cullin 4
K10609 CUL4; cullin 4
K10610 DDB1; DNA damage-binding protein 1
K10140 DDB2; DNA damage-binding protein 2
K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
K03011 RPB3; DNA-directed RNA polymerase II subunit RPB3
K03012 RPB4; DNA-directed RNA polymerase II subunit RPB4
K03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1
K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2
K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
K03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3
K03017 RPB9; DNA-directed RNA polymerase II subunit RPB9
K03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5
K03008 RPB11; DNA-directed RNA polymerase II subunit RPB11
K03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4
K10570 ERCC8; DNA excision repair protein ERCC-8
K10841 ERCC6; DNA excision repair protein ERCC-6
K23720 UVSSA; UV-stimulated scaffold protein A
K25829 ELOF1; transcription elongation factor 1
K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
K03141 TFIIH1; transcription initiation factor TFIIH subunit 1
K03142 TFIIH2; transcription initiation factor TFIIH subunit 2
K03143 TFIIH3; transcription initiation factor TFIIH subunit 3
K03144 TFIIH4; transcription initiation factor TFIIH subunit 4
K10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit
K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
K06634 CCNH; cyclin H
K10842 MNAT1; CDK-activating kinase assembly factor MAT1
K07466 RFA1; replication factor A1
K10739 RFA2; replication factor A2
K10740 RPA3; replication factor A3
K10741 RPA4; replication factor A4
K10847 XPA; DNA-repair protein complementing XP-A cells
K10849 ERCC1; DNA excision repair protein ERCC-1
K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
K10846 ERCC5; DNA excision repair protein ERCC-5
K15075 MET18; DNA repair/transcription protein MET18/MMS19
K03869 CUL3; cullin 3
K10612 CUL5; cullin 5
K03872 ELOC; elongin-C
K03873 ELOB; elongin-B
K15076 ELOA; elongin-A
K26545 UBAP2; ubiquitin-associated protein 2
K26545 UBAP2; ubiquitin-associated protein 2
K08735 MSH2; DNA mismatch repair protein MSH2
K08736 MSH3; DNA mismatch repair protein MSH3
K08737 MSH6; DNA mismatch repair protein MSH6
K10864 PMS1; DNA mismatch repair protein PMS1
K08734 MLH1; DNA mismatch repair protein MLH1
K10858 PMS2; DNA mismatch repair protein PMS2
K08739 MLH3; DNA mismatch repair protein MLH3
K10754 RFC1; replication factor C subunit 1
K10755 RFC2_4; replication factor C subunit 2/4
K10755 RFC2_4; replication factor C subunit 2/4
K10756 RFC3_5; replication factor C subunit 3/5
K10756 RFC3_5; replication factor C subunit 3/5
K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
K24755 WDR76; WD repeat-containing protein 76
K10865 MRE11; double-strand break repair protein MRE11
K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
K10867 NBN; nibrin
K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
K10683 BARD1; BRCA1-associated RING domain protein 1
K20774 FAM175A; BRCA1-A complex subunit Abraxas
K20775 UIMC1; BRCA1-A complex subunit RAP80
K20776 BABAM; BRISC and BRCA1-A complex member 1
K12173 BRE; BRCA1-A complex subunit BRE
K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
K15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]
K10728 TOPBP1; topoisomerase (DNA) II binding protein 1
K20773 RBBP8; DNA endonuclease RBBP8 [EC:3.1.-.-]
K08775 BRCA2; breast cancer 2 susceptibility protein
K10897 PALB2; partner and localizer of BRCA2
K04482 RAD51; DNA repair protein RAD51
K10869 RAD51L1; RAD51-like protein 1
K10870 RAD51L2; RAD51-like protein 2
K10871 RAD51L3; RAD51-like protein 3
K10879 XRCC2; DNA-repair protein XRCC2
K10880 XRCC3; DNA-repair protein XRCC3
K10873 RAD52; DNA repair and recombination protein RAD52
K10874 RDM1; RAD52 motif-containing protein 1
K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]
K10876 RAD54L2; RAD54-like protein 2 [EC:5.6.2.-]
K10877 RAD54B; DNA repair and recombination protein RAD54B [EC:5.6.2.-]
K10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]
K10900 WRN; werner syndrome ATP-dependent helicase [EC:5.6.2.4]
K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
K10730 RECQL4; ATP-dependent DNA helicase Q4 [EC:5.6.2.4]
K10902 RECQL5; ATP-dependent DNA helicase Q5 [EC:5.6.2.4]
K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
K10990 RMI1; RecQ-mediated genome instability protein 1
K15423 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]
K15424 PPP4R1; serine/threonine-protein phosphatase 4 regulatory subunit 1
K15424 PPP4R1; serine/threonine-protein phosphatase 4 regulatory subunit 1
K15425 PPP4R2; serine/threonine-protein phosphatase 4 regulatory subunit 2
K17491 SMEK; protein phosphatase 4 regulatory subunit 3
K17491 SMEK; protein phosphatase 4 regulatory subunit 3
K17491 SMEK; protein phosphatase 4 regulatory subunit 3
K15426 PPP4R4; serine/threonine-protein phosphatase 4 regulatory subunit 4
K19022 AP5B1; AP-5 complex subunit beta-1
K19023 AP5M1; AP-5 complex subunit mu-1
K19024 AP5S1; AP-5 complex subunit sigma-1
K19025 AP5Z1; AP-5 complex subunit zeta-1
K22803 SMC5; structural maintenance of chromosomes protein 5
K22804 SMC6; structural maintenance of chromosomes protein 6
K22805 FAM84A; protein FAM84A
K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]
K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]
K22823 NSMCE3; non-structural maintenance of chromosomes element 3
K22825 NSMCE4; non-structural maintenance of chromosomes element 4
K22826 EID3; EP300-interacting inhibitor of differentiation 3
K26126 SLF1; SMC5-SMC6 complex localization factor protein 1
K26127 SLF2; SMC5-SMC6 complex localization factor protein 2
K10882 EME1; crossover junction endonuclease EME1 [EC:3.1.22.-]
K10883 EME2; crossover junction endonuclease EME2
K20777 EXD2; exonuclease 3'-5' domain-containing protein 2 [EC:3.1.11.1]
K08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-]
K10881 SHFM1; 26 proteasome complex subunit DSS1
K10991 SWI5; DNA repair protein Swi5/Sae3
K10992 SFR1; Swi5-dependent recombination DNA repair protein 1
K15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]
K10484 BTBD12; structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
K15338 GEN1; holliday junction resolvase GEN1/YEN1 [EC:3.1.-.-]
K19026 SPG11; spatacsin
K19027 ZFYVE26; zinc finger FYVE domain-containing protein 26
K20778 RAD51AP1; RAD51-associated protein 1
K11339 MORF4L1; mortality factor 4-like protein 1
K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
K22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]
K22806 SPIDR; DNA repair-scaffolding protein
K22810 FAM84B; protein FAM84B
K23112 BRAT1; BRCA1-associated ATM activator 1
K23456 CFAP410; cilla- and flagella-associated protein
K25065 HDGFL2; hepatoma-derived growth factor-related protein 2
K25770 ZSWIM7; zinc finger SWIM domain-containing protein 7
K25771 SWSAP1; ATPase SWSAP1
K25790 EMSY; BRCA2-interacting transcriptional repressor EMSY
K25791 HSF2BP; heat shock factor 2-binding protein
K26125 MMS22L; protein MMS22-like
K09257 NFKBIL2; NF-kappa-B inhibitor-like protein 2
K27262 BOD1L1; biorientation of chromosomes in cell division protein 1-like 1
K27412 PARPBP; PCNA-interacting partner
K10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1
K10885 XRCC5; ATP-dependent DNA helicase 2 subunit 2
K06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]
K10777 LIG4; DNA ligase 4 [EC:6.5.1.1]
K10886 XRCC4; DNA-repair protein XRCC4
K10980 NHEJ1; non-homologous end-joining factor 1
K03513 POLM; DNA polymerase mu [EC:2.7.7.7]
K00977 DNTT; DNA nucleotidylexotransferase [EC:2.7.7.31]
K10887 DCLRE1C; DNA cross-link repair 1C protein [EC:3.1.-.-]
K19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]
K23113 SMCHD1; structural maintenance of chromosomes flexible hinge domain-containing protein 1
K23386 PWWP3; PWWP domain-containing DNA repair factor 3
K23386 PWWP3; PWWP domain-containing DNA repair factor 3
K23386 PWWP3; PWWP domain-containing DNA repair factor 3
K25772 PAXX; protein PAXX
K26155 CYREN; cell cycle regulator of non-homologous end joining
K25792 JMJD8; jumonji domain-containing protein 8
K26128 SHLD1; shieldin complex subunit 1
K26129 SHLD2; shieldin complex subunit 2
K10888 FANCA; fanconi anemia group A protein
K10889 FANCB; fanconi anemia group B protein
K10890 FANCC; fanconi anemia group C protein
K10892 FANCE; fanconi anemia group E protein
K10893 FANCF; fanconi anemia group F protein
K10894 FANCG; fanconi anemia group G protein
K10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]
K10896 FANCM; fanconi anemia group M protein
K10898 FAAP24; fanconi anemia-associated protein
K10993 FAAP100; fanconi anemia core complex 100 kDa subunit
K06054 HES1; hairy and enhancer of split 1
K11511 APITD1; centromere protein S
K15360 STRA13; centromere protein X
K13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23]
K10891 FANCD2; fanconi anemia group D2 protein
K10895 FANCI; fanconi anemia group I protein
K15363 FAN1; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1]
K15363 FAN1; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1]
K11137 TELO2; telomere length regulation protein
K11832 USP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]
K15361 WDR48; WD repeat-containing protein 48
K15498 PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]
K15499 PPP6R1; serine/threonine-protein phosphatase 6 regulatory subunit 1
K15500 PPP6R2; serine/threonine-protein phosphatase 6 regulatory subunit 2
K15501 PPP6R3; serine/threonine-protein phosphatase 6 regulatory subunit 3
K15502 ANKRD28; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A
K15503 ANKRD44; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B
K15504 ANKRD52; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C
K10667 RNF8; E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27]
K20779 RNF168; E3 ubiquitin-protein ligase RNF168 [EC:2.3.2.31]
K20805 RNF169; E3 ubiquitin-protein ligase RNF169 [EC:2.3.2.31]
K10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26]
K23314 WRAP53; telomerase Cajal body protein 1
K24164 TPRN; taperin
K24688 ZCWPW1; zinc finger CW-type PWWP domain protein 1
K24752 WDR70; WD repeat-containing protein 70
K03509 POLH; DNA polymerase eta [EC:2.7.7.7]
K03510 POLI; DNA polymerase iota [EC:2.7.7.7]
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K03515 REV1; DNA repair protein REV1 [EC:2.7.7.-]
K02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]
K16618 POLN; DNA polymerase nu [EC:2.7.7.7]
K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
K10574 UBE2B; ubiquitin-conjugating enzyme E2 B [EC:2.3.2.23]
K10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]
K15711 SMARCA3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]
K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
K24051 SPRTN; SprT-like domain-contaning protein Spartan
K26957 GCNA; germ cell nuclear acidic protein
K10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]
K10995 RAD9B; cell cycle checkpoint control protein RAD9B
K10903 HUS1; HUS1 checkpoint protein
K10996 HUS1B; checkpoint protein HUS1B
K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
K06662 HRAD17; cell cycle checkpoint protein
K10997 TIMELESS; replication fork protection complex subunit TIMELESS/Tof1/Swi1
K10998 TIPIN; replication fork protection complex subunit TIPIN/Csm3/Swi3
K25773 CLSPN; claspin
K20403 TTI1; TELO2-interacting protein 1
K23115 TTI2; TELO2-interacting protein 2
K23390 BAG6; large proline-rich protein BAG6
K23388 UBL4; ubiquitin-like protein 4
K23388 UBL4; ubiquitin-like protein 4
K23387 GET4; golgi to ER traffic protein 4
K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
K10905 ATRIP; ATR interacting protein
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K04451 TP53; tumor protein p53
K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
K06645 CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48]
K05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
K05867 CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48]
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K06630 YWHAE; 14-3-3 protein epsilon
K19483 NAV2; neuron navigator 2 [EC:5.6.2.4]
K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
K21944 PER1; period circadian protein 1
K02633 PER2; period circadian protein 2
K21945 PER3; period circadian protein 3
K20780 MDC1; mediator of DNA damage checkpoint protein 1
K17336 PLS3; plastin-3
K18340 AEN; apoptosis-enhancing nuclease [EC:3.1.-.-]
K08862 PLK3; polo-like kinase 3 [EC:2.7.11.21]
K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1]
K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1]
K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1]
K20879 NEK10; serine/threonine-protein kinase Nek10 [EC:2.7.11.1]
K20880 NEK11; serine/threonine-protein kinase Nek11 [EC:2.7.11.1]
K22422 DONSON; protein downstream neighbor of Son
K22808 KANK; KN motif and ankyrin repeat domain-containing protein
K22808 KANK; KN motif and ankyrin repeat domain-containing protein
K22808 KANK; KN motif and ankyrin repeat domain-containing protein
K22808 KANK; KN motif and ankyrin repeat domain-containing protein
K23389 KLLN; killin
K24458 SLFN11; schlafen family member 11 [EC:3.6.-.-]
K24782 CHMP4C; charged multivesicular body protein 4C
K12196 VPS4; vacuolar protein-sorting-associated protein 4
K12196 VPS4; vacuolar protein-sorting-associated protein 4
K24778 ZFYVE19; abscission/NoCut checkpoint regulator
K25059 SDE2; replication stress response regulator SDE2
K02349 POLQ; DNA polymerase theta [EC:2.7.7.7]
K02331 POL5; DNA polymerase phi [EC:2.7.7.7]
K22761 PRIMPOL; DNA-directed primase/polymerase protein [EC:2.7.7.102 2.7.7.7]
K10790 TREX1; three prime repair exonuclease 1 [EC:3.1.11.2]
K10791 TREX2; three prime repair exonuclease 2 [EC:3.1.11.2]
K15340 DCLRE1A; DNA cross-link repair 1A protein
K15341 DCLRE1B; DNA cross-link repair 1B protein [EC:3.1.-.-]
K17815 EXO5; exonuclease V [EC:3.1.-.-]
K21813 ENDOV; endonuclease V [EC:3.1.26.-]
K25861 ZRANB3; DNA annealing helicase and endonuclease ZRANB3 [EC:5.6.2.- 3.1.-.-]
K21411 ANKLE1; ankyrin repeat and LEM domain-containing protein 1
K19178 HELQ; POLQ-like helicase [EC:5.6.2.4]
K20098 ERCC6L2; DNA excision repair protein ERCC-6-like 2 [EC:5.6.2.-]
K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
K12860 CDC5L; pre-mRNA-splicing factor CDC5/CEF1
K12861 BCAS2; pre-mRNA-splicing factor SPF27
K12862 PLRG1; pleiotropic regulator 1
K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
K17817 NUDT18; 8-oxo-dGDP phosphatase [EC:3.6.1.58]
K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
K03111 ssb; single-strand DNA-binding protein
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03029 Mitochondrial biogenesis [BR:pale03029]
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09183 Protein families: signaling and cellular processes
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09185 Viral protein families
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09184 RNA family
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09190 Not Included in Pathway or Brite
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KEGG Orthology (KO) - Pteropus alecto (black flying fox)