KEGG   ORTHOLOGY: K07374
Entry
K07374                      KO                                     
Symbol
TUBA
Name
tubulin alpha
Pathway
map04145  Phagosome
map04210  Apoptosis
map04530  Tight junction
map04540  Gap junction
map04814  Motor proteins
map05010  Alzheimer disease
map05012  Parkinson disease
map05014  Amyotrophic lateral sclerosis
map05016  Huntington disease
map05020  Prion disease
map05022  Pathways of neurodegeneration - multiple diseases
map05130  Pathogenic Escherichia coli infection
map05132  Salmonella infection
Disease
H00058  Amyotrophic lateral sclerosis (ALS)
H00268  Lissencephaly
H00789  Keratoconus
H01740  Macrothrombocytopenia
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    K07374  TUBA; tubulin alpha
  09143 Cell growth and death
   04210 Apoptosis
    K07374  TUBA; tubulin alpha
  09144 Cellular community - eukaryotes
   04530 Tight junction
    K07374  TUBA; tubulin alpha
   04540 Gap junction
    K07374  TUBA; tubulin alpha
  09142 Cell motility
   04814 Motor proteins
    K07374  TUBA; tubulin alpha
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    K07374  TUBA; tubulin alpha
   05132 Salmonella infection
    K07374  TUBA; tubulin alpha
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K07374  TUBA; tubulin alpha
   05012 Parkinson disease
    K07374  TUBA; tubulin alpha
   05014 Amyotrophic lateral sclerosis
    K07374  TUBA; tubulin alpha
   05016 Huntington disease
    K07374  TUBA; tubulin alpha
   05020 Prion disease
    K07374  TUBA; tubulin alpha
   05022 Pathways of neurodegeneration - multiple diseases
    K07374  TUBA; tubulin alpha
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis
    K07374  TUBA; tubulin alpha
   03036 Chromosome and associated proteins
    K07374  TUBA; tubulin alpha
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins
    K07374  TUBA; tubulin alpha
   04147 Exosome
    K07374  TUBA; tubulin alpha
Messenger RNA biogenesis [BR:ko03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   mRNA cycle factors
    P-body specific factors
     K07374  TUBA; tubulin alpha
Chromosome and associated proteins [BR:ko03036]
 Eukaryotic type
  Centrosome formation proteins
   Microtubules and associated factors
    Other tubulins
     K07374  TUBA; tubulin alpha
Cytoskeleton proteins [BR:ko04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulins
    K07374  TUBA; tubulin alpha
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   K07374  TUBA; tubulin alpha
  Exosomal proteins of other body fluids (saliva and urine)
   K07374  TUBA; tubulin alpha
  Exosomal proteins of colorectal cancer cells
   K07374  TUBA; tubulin alpha
Other DBs
GO: 0005874
Genes
HSA: 10376(TUBA1B) 112714(TUBA3E) 113457(TUBA3D) 51807(TUBA8) 7277(TUBA4A) 7278(TUBA3C) 7846(TUBA1A) 79861(TUBAL3) 84790(TUBA1C)
PTR: 104004490(TUBA5) 107973630 129135336 129143398 451875(TUBA1A) 451876(TUBA1C) 452423(TUBA1B) 458641(TUBA8) 465169(TUBA3C) 466007(TUBAL3) 470654(TUBA4A)
PPS: 100970502(TUBA1C) 100973193 100975223 100986068(TUBA8) 100989319(TUBAL3) 100993058 100993591 100995882(TUBA4A) 103782837 129397330
GGO: 101128742 101129375(TUBA1C) 101135000(TUBA3E) 101136583 101145095(TUBA8) 101148853 101148972 101149435(TUBAL3) 101150168 115933728 129526434
PON: 100434822 100436042(TUBAL3) 100439587 100439869 100444582(TUBA8) 100445003(TUBA1B) 100445613(TUBA1A) 100446260 100449357 112129091
PPYG: 129009401 129009402(TUBA1A) 129009403 129011855 129022341 129023451(TUBA8) 129031836 129032082 129044528 129045191(TUBAL3) 134737991
NLE: 100582452(TUBA8) 100583522(TUBA4A) 100585215 100585634 100587604 100592992(TUBA3E) 100599731(TUBA4B) 100602647 100602904(TUBAL3) 100604350
HMH: 116459291 116461664(TUBA1A) 116461665 116461669 116462964 116467188 116468915 116474604(TUBAL3)
SSYN: 129463914 129467795(TUBA8) 129471894 129484758 129488464(TUBA4A) 129491113(TUBA1C) 129491115 129491118 129491682(TUBAL3)
MCC: 574194(TUBA1A) 702583(TUBA4A) 707215 709643(TUBA1B) 710110 710378(TUBA8) 718034(TUBA3E) 722506(TUBAL3)
MCF: 101865772(TUBA1A) 101867105(TUBA8) 101867500(TUBA1B) 101925452 101926805(TUBA4A) 102121218 102128802 102145991(TUBAL3)
CSAB: 103216844(TUBA3E) 103217904(TUBA4A) 103222884(TUBA8) 103237818(TUBAL3) 103238260(TUBA1B) 103238261(TUBA1A) 103238262 103247857
CANG: 105504700(TUBA4A) 105507630(TUBA1C) 105507633 105507635 105514344(TUBA8) 105522542(TUBAL3) 105527496
MMU: 22142(Tuba1a) 22143(Tuba1b) 22144(Tuba3a) 22145(Tuba4a) 22146(Tuba1c) 22147(Tuba3b) 238463(Tubal3) 53857(Tuba8)
RNO: 291287(Tubal3) 300218(Tuba1c) 316531(Tuba4a) 500319(Tuba3a) 500363(Tuba3b) 500377(Tuba8) 500929(Tuba1b) 64158(Tuba1a)
CGE: 100682526(Tuba1c) 100682527(Tuba1a) 100682528(Tuba1b) 100753526(Tuba8) 100755907(Tubal3) 100762888 100765599 100767630 100767686(Tuba4a) 113832602
DORD: 105980368(Tubal3) 105981516 105987526(Tuba1c) 105987533 105991067(Tuba8) 105996598(Tuba4a) 105997194(Tuba3e) 105997195
TUP: 102470651 102480185(TUBAL3) 102481330(TUBA8) 102492330 102494910(TUBA1C) 102496008(TUBA4A) 102496850 102501396(TUBA3E) 102503378(TUBA3D) 106733869
PTG: 102950928(TUBA8) 102951399 102953141 102953725(TUBA1C) 102954023 102962068(TUBA4A) 102969257(TUBAL3)
BTA: 100141266 100295712 112443216 404053(TUBA1A) 504244(TUBA1C) 534900(TUBA3E) 535605(TUBA1D) 539882(TUBA1B) 768036(TUBA8) 777775(TUBA4A) 782966
SSC: 100127131 100135051(TUBA1A) 100151951(TUBA4A) 100155138 100158003 100510930 100518253(TUBA8) 100623355(TUBAL3) 733594(TUBA1B)
BACU: 103007004(TUBA4A) 103007507 103011731(TUBA8) 103011769(TUBAL3) 103018473 103018852(TUBA1B) 103019471 103019847(TUBA1A) 103020122(TUBA1C) 103020611
LVE: 103072784(TUBA4A) 103073687 103075111(TUBAL3) 103080842(TUBA1B) 103081399(TUBA1A) 103081669(TUBA1C) 103082790 103086172 103088880 103089420(TUBA8)
SHON: 118975343 118975433(TUBA4A) 118976453 118976454 118976455(TUBA1C) 118980600(TUBA3C) 118995139(TUBA8) 119000771(TUBAL3) 119001898
PHAS: 123806560 123812863 123812864(TUBA1C) 123818736(TUBA8) 123822762(TUBA3C) 123828105 123831161(TUBAL3)
MDO: 100010238(TUBA4A) 100010347(TUBA1B) 100010436(TUBA1A) 100010481 100015203 100022210(TUBA8) 100025645(TUBA3E)
GGA: 100857214(TUBA4B) 100857247(TUBA4A) 100857858(TUBA1C) 100859737(TUBA1A1) 396426(TUBA8B) 416694(TUBAL3) 416695 418166(TUBA8A) 421169(TUBA3E) 425049 429035(TUBA1C)
PMAJ: 107198580 107198581 107204161(TUBAL3) 107204967(TUBA8) 107207622(TUBA4A) 107209044(TUBA3C) 107214939
ETL: 114055068(TUBA4A) 114061402 114064794 114068958(TUBA8)
XLA: 100036943(tuba8.S) 100337592(tuba1c.L) 108701830(tuba1cl.2.L) 108702924(tuba4b.S) 108702925(tuba1cl.2.S) 108702929 108702930(tuba1cl.3.S) 108708119(tuba5.L) 108708550(tuba1b.L) 108708551(tuba1a.L) 108709821(tuba1b.S) 108709822(tuba1a.S) 108711234(tubal3.2.L) 121397893 379210(tuba5.S) 379748(tuba1cl.3.L) 380482(tuba1c.S) 397931(tubal3.1.L) 431994(tubal3.1.S) 493577(tuba4b.L) 496021(tuba1l.S) 733413(tuba1al.L) 779368(tuba8.L)
XTR: 100037894(tuba8) 100038108(tuba1b) 100038123(tuba1a) 100144986(tuba1l) 100486465(tuba1al) 100490289(tuba1cl.1) 100497157 100497528(tuba1cl.2) 394675(tuba1c) 394734(tuba1cl.3) 407878(tubal3.1) 548558(tubal3.2) 548688(tuba3c) 549448(tuba4b)
DRE: 327377(tuba4l) 337223(tuba5) 373080(tuba1b) 393154(tuba8l4) 393664(tuba8l2) 406303(tuba2) 431777(tuba7l) 445164(tuba8l3) 573122(tuba1c) 573216(tuba1a) 641561(zgc:123298) 792024(tuba8l5) 795591(si:ch211-114n24.6)
PTET: 122328643 122328644 122328645 122333754(tuba7l) 122345986(tuba8l2) 122347343(tuba8l4) 122350646(tuba5) 122351230(tuba8l3) 122352131 122354125 122357121(tuba4l)
LROH: 127154810(tuba1c) 127155124(tuba1a) 127161297 127161298 127166595(si:ch211-114n24.6) 127166743(tuba8l4) 127168693(tuba8l2) 127169771(tuba5) 127170645(tuba8l3) 127172328(tuba7l) 127175612(tuba4l)
OMC: 131532222(tuba1c) 131532290(tuba1a) 131532291 131538389(tuba8l2) 131542213 131542214(tuba8l4) 131545288(tuba5) 131547279 131547280 131547889(tuba7l) 131548963 131551752(tuba4l)
MAMB: 125256467 125256468 125259547 125259548 125262398(tuba7l) 125270112 125272858(tuba8l2) 125274156(tuba8l4) 125274157(si:ch211-114n24.6) 125279738(tuba5)
MANU: 129414545(tuba5) 129418777 129430848 129430849(tuba1c) 129433592 129434116 129445066(tuba8l2) 129446474(tuba7l) 129450503 129451089(si:ch211-114n24.6) 129452415
DME: Dmel_CG1913(alphaTub84B) Dmel_CG2512(alphaTub84D) Dmel_CG7794(CG7794) Dmel_CG8308(alphaTub67C) Dmel_CG9476(alphaTub85E)
DSI: Dsimw501_GD14204(Dsim_GD14204) Dsimw501_GD19196(Dsim_GD19196) Dsimw501_GD19909(Dsim_GD19909) Dsimw501_GD19940(Dsim_GD19940) Dsimw501_GD20767(Dsim_GD20767)
TCA: 655491 656061 656649(Tub84B) 662929
BMOR: 101745545 101745769 692428(Tua1) 692429(Tua2) 692430(Tua3)
CEL: CELE_C44B11.3(mec-12) CELE_C47B2.3(tba-2) CELE_F16D3.1(tba-5) CELE_F26E4.8(tba-1) CELE_F32H2.9(tba-6) CELE_F40F4.5(tba-9) CELE_F44F4.11(tba-4) CELE_T28D6.2(tba-7) CELE_ZK899.4(tba-8)
CBR: CBG_03797(Cbr-tba-1) CBG_04075(Cbr-tba-5) CBG_07939 CBG_12412(Cbr-tba-6) CBG_13220(Cbr-tba-7) CBG_14166(Cbr-tba-9) CBG_16131(Cbr-tba-8) CBG_20310(Cbr-mec-12)
BMY: BM_BM10379(Bma-tba-5) BM_BM2748(Bm2748) BM_BM7583(Bma-tba-8) BM_BM8306(Bm8306) BM_BM9228(Bm9228)
SHX: MS3_00005438(MEC-12_1) MS3_00008342(TUBA3D_3) MS3_00008742(TUBA3D_5)
ATH: AT1G04820(TUA4) AT1G50010(TUA2) AT1G64740(TUA1) AT4G14960(TUA6) AT5G19770(TUA3) AT5G19780(TUA5)
OSA: 4332083 4333966 4343694(tubA) 4350197(TID1)
APRO: F751_0542
MIS: MICPUN_92378(TUA1) MICPUN_94939(TUA2)
SCE: YML085C(TUB1) YML124C(TUB3)
ERC: Ecym_1387
KMX: KLMA_70260(TUB1)
CGR: 2886518(GVI51_B02387)
NCS: NCAS_0B00210(NCAS0B00210) NCAS_0C00260(NCAS0C00260)
NDI: NDAI_0K00270(NDAI0K00270)
TPF: TPHA_0C04840(TPHA0C04840) TPHA_0I00180(TPHA0I00180)
TBL: TBLA_0B02950(TBLA0B02950)
TDL: TDEL_0B00280(TDEL0B00280)
KAF: KAFR_0A02920(KAFR0A02920) KAFR_0L02020(KAFR0L02020)
KNG: KNAG_0G03540(KNAG0G03540)
PIC: PICST_89181(TUB1)
LEL: PVL30_002471(TUB1)
LBG: 92207087(LODBEIA_P18910)
CAL: CAALFM_CR09120CA(TUB1)
CDU: CD36_34530(TUB1)
CTEN: 18248664(TUB1)
BNN: FOA43_003041(TUB1)
BBRX: BRETT_005291(TUB1)
YLI: 2911759(YALI2_E00388g)
SLB: AWJ20_358(TUB1)
NCR: NCU09132(tba-1) NCU09468(tba-2)
NTE: NEUTE1DRAFT117196(NEUTE1DRAFT_117196) NEUTE1DRAFT90760(NEUTE1DRAFT_90760)
SMP: 10808725(SMAC4_08161)
PBEL: QC761_0058840(TUB1_2) QC761_103600(TUB1_3)
PPSD: QC762_103600(TUB1_1) QC762_310220(TUB1_2)
PPSP: QC763_103600(TUB1_1) QC763_310220(TUB1_2)
PPSA: QC764_103600(TUB1_1) QC764_310220(TUB1_2)
FPOA: FPOAC1_000417(TUB1_1) FPOAC1_000665(TUB1_2)
FMU: J7337_001137(TUB1_1) J7337_001411(TUB1_2)
TATV: 25774929(TrAtP1_004447) 25780149(TrAtP1_005729)
TASP: 36611459(TUB1_1) 36613610(TUB1_2)
MAW: 19247517(TUB1_3) 19249968(TUB1_1)
MBRN: 26239449(TUB1_0) 26240512(TUB1_1)
PLJ: 28887309(PLICBS_002571) 28889225(PLICBS_008315)
PTKZ: JDV02_001287(TUB1_1) JDV02_006334(TUB1_2)
CDET: 87943053(CDEST_06550) 87946378(CDEST_09876)
CPW: 9691257(D8B26_001770) 9695129(TUB1)
TVE: TRV_02183
PBL: PAAG_01647 PAAG_12506(PAAG_08104)
PTRR: 6341710(PtrM4_098590) 6346089(PtrM4_138370)
SPO: 2539864(nda2) 2540936(atb2)
SOM: SOMG_02184(atb2) SOMG_03452(nda2)
CNE: CNB02810
CNB: CNBB2870
CDEU: CNBG_0187
CDEP: 91084697(L203_100481)
KMG: 30164964(I203_108260)
KNE: 92177601(IAR55_000341)
TASA: A1Q1_03326
CCAC: CcaHIS019_0202990(TUB1)
ABP: AGABI1DRAFT84548(AGABI1DRAFT_84548)
ABV: AGABI2DRAFT135559(AGABI2DRAFT_135559)
MORE: E1B28_004161(TUB1A) E1B28_004162(TUB1B)
SCM: SCHCO_02498526(SCHCODRAFT_02498526) SCHCO_02623036(SCHCODRAFT_02623036)
MGL: MGL_4211
MRT: MRET_1420
MBR: MONBRDRAFT_17634(TUA)
DFA: DFA_03741(tubA) DFA_04645
EHI: EHI_005950(83.t00009) EHI_010530(249.t00013)
PLAG: 39740297(PADL01_0421000) 39741557(PADL01_0902700)
PBRS: 92369613(MKS88_001525) 92369914(MKS88_001826)
BDW: 94336520(BdWA1_002222)
CPV: cgd4_2860
FCY: FRACYDRAFT_169390(TUBA_1)
TPS: THAPSDRAFT_29304(TUB1)
BLAC: 94347165(CCR75_003399) 94352597(CCR75_008879) 94352598(CCR75_008880)
TCR: 411235.9
LMAT: 92515790(LSCM1_05840) 92515791(LSCM1_05841) 92515792(LSCM1_05842) 92515793(LSCM1_05843) 92515794(LSCM1_05844) 92515795(LSCM1_05846) 92515796(LSCM1_05847) 92515797(LSCM1_05848) 92515798(LSCM1_05849) 92515799(LSCM1_05850) 92515800(LSCM1_05851) 92515801(LSCM1_05852) 92515926(LSCM1_05980) 92515927(LSCM1_05981) 92515928(LSCM1_05982) 92515929(LSCM1_05983) 92515930(LSCM1_05984)
LOI: 92363680(LSCM4_07869)
LEIS: 94183003(GH5_07776) 94183004(GH5_07777)
PHET: 94292245(JKF63_06218) 94292246(JKF63_06219) 94292247(JKF63_06220) 94292248(JKF63_06221) 94292249(JKF63_06222) 94292250(JKF63_06223) 94292251(JKF63_06224) 94292252(JKF63_06225) 94292253(JKF63_06226) 94292254(JKF63_06227) 94292255(JKF63_06228) 94292256(JKF63_06229) 94292257(JKF63_06230)
SSAO: 94294111(SS50377_20088) 94294113(SS50377_20090) 94294115(SS50377_20092) 94300848(SS50377_26825) 94302736(SS50377_28713)
NDV: NDEV_1590
 » show all
Reference
PMID:6646120
  Authors
Cowan NJ, Dobner PR, Fuchs EV, Cleveland DW
  Title
Expression of human alpha-tubulin genes: interspecies conservation of 3' untranslated regions.
  Journal
Mol Cell Biol 3:1738-45 (1983)
DOI:10.1128/mcb.3.10.1738
  Sequence
[hsa:7846]
Reference
PMID:9885292
  Authors
Fukushige T, Siddiqui ZK, Chou M, Culotti JG, Gogonea CB, Siddiqui SS, Hamelin M
  Title
MEC-12, an alpha-tubulin required for touch sensitivity in C. elegans.
  Journal
J Cell Sci 112 ( Pt 3):395-403 (1999)
  Sequence
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