 09100 Metabolism
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09120 Genetic Information Processing
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 09130 Environmental Information Processing
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09131 Membrane transport
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09132 Signal transduction
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02020 Two-component system [PATH:ko02020]
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04010 MAPK signaling pathway [PATH:ko04010]
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04013 MAPK signaling pathway - fly [PATH:ko04013]
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04016 MAPK signaling pathway - plant [PATH:ko04016]
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04011 MAPK signaling pathway - yeast [PATH:ko04011]
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04012 ErbB signaling pathway [PATH:ko04012]
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04014 Ras signaling pathway [PATH:ko04014]
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04015 Rap1 signaling pathway [PATH:ko04015]
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04310 Wnt signaling pathway [PATH:ko04310]
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04330 Notch signaling pathway [PATH:ko04330]
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04340 Hedgehog signaling pathway [PATH:ko04340]
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04341 Hedgehog signaling pathway - fly [PATH:ko04341]
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04350 TGF-beta signaling pathway [PATH:ko04350]
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04390 Hippo signaling pathway [PATH:ko04390]
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04391 Hippo signaling pathway - fly [PATH:ko04391]
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04392 Hippo signaling pathway - multiple species [PATH:ko04392]
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04370 VEGF signaling pathway [PATH:ko04370]
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04371 Apelin signaling pathway [PATH:ko04371]
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04630 JAK-STAT signaling pathway [PATH:ko04630]
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 K05429 IL2; interleukin 2
K04736 IL3; interleukin 3
K05430 IL4; interleukin 4
K05428 IL5; interleukin 5
K05405 IL6; interleukin 6
K05431 IL7; interleukin 7
K05432 IL9; interleukin 9
K05443 IL10, CSIF; interleukin 10
K05417 IL11; interleukin 11
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05435 IL13; interleukin 13
K05433 IL15; interleukin 15
K05492 IL17D, IL27; interleukin 17D
K05444 IL19; interleukin 19
K22667 IL20; interleukin 20
K05434 IL21; interleukin 21
K05445 IL22, IL-TIF; interleukin 22
K05426 IL23A; interleukin 23 subunit alpha
K22668 IL24; interleukin 24
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K04687 IFNG; interferon gamma
K05442 IFNE; interferon epsilon
K05441 IFNK; interferon kappa
K05447 IFNL1, IL29; interferon lambda 1
K22669 IFNL2_3, IL28; interferon lambda 2/3
K05440 IFNW; interferon omega
K05418 OSM; oncostatin M
K05419 LIF; leukemia inhibitory factor
K05436 TSLP; thymic stromal lymphopoietin
K05422 CTF1, CT1; cardiotrophin 1
K24382 CTF2; cardiotrophin 2
K05427 CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
K16689 UPD; unpaired
K05420 CNTF; ciliary neurotrophic factor
K05423 CSF3, GCSF; granulocyte colony-stimulating factor
K05437 EPO; erythropoietin
K05438 GH; growth hormone
K05424 LEP; leptin
K06854 THPO; thrombopoietin
K05439 PRL; prolactin
K04357 EGF; epidermal growth factor
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K05068 IL2RA, CD25; interleukin 2 receptor alpha
K05069 IL2RB, CD122; interleukin 2 receptor beta
K05070 IL2RG, CD132; interleukin 2 receptor gamma
K04737 IL3RA, CD123; interleukin 3 receptor alpha
K05071 IL4R, CD124; interleukin 4 receptor
K05067 IL5RA. CD125; interleukin 5 receptor alpha
K05055 IL6R, CD126; interleukin 6 receptor
K05072 IL7R, CD127; interleukin 7 receptor
K05073 IL9R, CD129; interleukin 9 receptor
K05134 IL10RA, CD210A; interleukin 10 receptor alpha
K05135 IL10RB, CD210B; interleukin 10 receptor beta
K05056 IL11RA; interleukin 11 receptor alpha
K05063 IL12RB1, CD212; interleukin 12 receptor beta-1
K05064 IL12RB2; interleukin 12 receptor beta-2
K05076 IL13RA1, CD213A1; interleukin 13 receptor alpha-1
K05077 IL13RA2, CD213A2; interleukin 13 receptor alpha-2
K05074 IL15RA, CD215; interleukin 15 receptor alpha
K05136 IL20RA; interleukin 20 receptor alpha
K05137 IL20RB; interleukin 20 receptor beta
K05075 IL21R, CD360; interleukin 21 receptor
K05138 IL22RA1; interleukin 22 receptor alpha 1
K05139 IL22RA2; interleukin 22 receptor alpha 2
K05065 IL23R; interleukin 23 receptor
K19598 IL27RA; interleukin 27 receptor alpha
K05060 IL6ST, GP130, CD130; interleukin 6 signal transducer
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K05132 IFNGR1, CD119; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K05140 IFNLR1, IL28RA; interferon lambda receptor 1
K05057 OSMR; oncostatin M receptor
K05058 LIFR, CD118; leukemia inhibitory factor receptor
K05078 TSLPR; thymic stromal-derived lymphopoietin receptor
K05059 CNTFR; ciliary neurotrophic factor receptor
K05066 CSF2RA, GMCSFR, CD116; granulocyte-macrophage colony-stimulating factor receptor alpha
K04738 CSF2RB, IL3RB, CD131; cytokine receptor common subunit beta
K05061 CSF3R, CD114; granulocyte colony-stimulating factor receptor
K05079 EPOR; erythropoietin receptor
K05080 GHR; growth hormone receptor
K05062 LEPR, CD295; leptin receptor
K05082 TPOR, MPL, CD110; thrombopoietin receptor
K05081 PRLR; prolactin receptor
K19599 DOME; cytokine receptor domeless
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K04363 PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K04692 STAT3; signal transducer and activator of transcription 3
K11222 STAT4; signal transducer and activator of transcription 4
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K11225 STAT6; signal transducer and activator of transcription 6
K04701 CISH; cytokine inducible SH2-containing protein
K04694 SOCS1, JAB; suppressor of cytokine signaling 1
K04695 SOCS2, CIS2; suppressor of cytokine signaling 2
K04696 SOCS3, CIS3; suppressor of cytokine signaling 3
K04697 SOCS4; suppressor of cytokine signaling 4
K04698 SOCS5; suppressor of cytokine signaling 5
K04699 SOCS6_7; suppressor of cytokine signaling 6/7
K02161 BCL2; apoptosis regulator Bcl-2
K02539 MCL1; myeloid leukemia cell differntiation protein MCL-1
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K04702 PIM1; proto-oncogene serine/threonine-protein kinase Pim-1 [EC:2.7.11.1]
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K00157 AOX; aldehyde oxidase [EC:1.2.3.1]
K05640 GFAP; glial fibrillary acidic protein
K04705 STAM; signal transducing adaptor molecule
K18026 PTPN2, PTPT; tyrosine-protein phosphatase non-receptor type 2 [EC:3.1.3.48]
K05697 PTPN6, SHP-1; tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]
K04693 IRF9, ISGF3G, P48; interferon regulatory factor 9
K04498 EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
K04706 PIAS1; E3 SUMO-protein ligase PIAS1 [EC:2.3.2.-]
K16063 PIAS2; E3 SUMO-protein ligase PIAS2 [EC:2.3.2.-]
K16064 PIAS3; E3 SUMO-protein ligase PIAS3 [EC:2.3.2.-]
K16065 PIAS4; E3 SUMO-protein ligase PIAS4 [EC:2.3.2.27]
K14365 FHL1, SLIM1; four and a half LIM domains protein 1
K07293 PTPN11; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
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04064 NF-kappa B signaling pathway [PATH:ko04064]
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04668 TNF signaling pathway [PATH:ko04668]
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04066 HIF-1 signaling pathway [PATH:ko04066]
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04068 FoxO signaling pathway [PATH:ko04068]
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04020 Calcium signaling pathway [PATH:ko04020]
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04070 Phosphatidylinositol signaling system [PATH:ko04070]
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04072 Phospholipase D signaling pathway [PATH:ko04072]
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04071 Sphingolipid signaling pathway [PATH:ko04071]
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04024 cAMP signaling pathway [PATH:ko04024]
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04022 cGMP-PKG signaling pathway [PATH:ko04022]
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04151 PI3K-Akt signaling pathway [PATH:ko04151]
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K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K09784 EREG; epiregulin
K09782 AREG; amphiregulin
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K05451 NGFA; nerve growth factor, alpha
K02582 NGFB; nerve growth factor, beta
K04355 BDNF; brain-derived neurotrophic factor
K04356 NTF3; neurotrophin 3
K12457 NTF4; neurotrophin 4
K04526 INS; insulin
K05459 IGF1; insulin-like growth factor 1
K13769 IGF2; insulin-like growth factor 2
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K05450 PDGFC_D; platelet derived growth factor C/D
K05453 CSF1, MCSF; macrophage colony-stimulating factor 1
K05461 KITLG; KIT ligand
K05454 FLT3LG; fms-related tyrosine kinase 3 ligand
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K16859 PGF; placenta growth factor
K05449 VEGFC_D; vascular endothelial growth factor C/D
K05460 HGF; hepatocyte growth factor
K05465 ANGPT1; angiopoietin 1
K05466 ANGPT2; angiopoietin 2
K05467 ANGPT4; angiopoietin 4
K05462 EFNA; ephrin-A
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2, HER2, CD340; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K05084 ERBB3, HER3; receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1]
K05085 ERBB4, HER4; receptor tyrosine-protein kinase erbB-4 [EC:2.7.10.1]
K04362 FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2, CD332; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3, CD333; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4, CD334; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K02583 NGFR, TNFRSF16, CD271; tumor necrosis factor receptor superfamily member 16
K03176 NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K04360 NTRK2, TRKB; neurotrophic tyrosine kinase receptor type 2 [EC:2.7.10.1]
K04527 INSR, CD220; insulin receptor [EC:2.7.10.1]
K05087 IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04363 PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05090 CSF1R, FMS, CD115; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K05091 KIT, SCFR, CD117; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K05092 FLT3, FLK2, CD135; fms-related tyrosine kinase 3 [EC:2.7.10.1]
K05096 FLT1, VEGFR1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
K05097 FLT4, VEGFR3; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K05098 KDR, VEGFR2, CD309; kinase insert domain protein receptor [EC:2.7.10.1]
K05099 MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K05121 TEK, TIE2, CD202; endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]
K05103 EPHA2, ECK; Eph receptor A2 [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K16172 IRS1; insulin receptor substrate 1
K10159 TLR2, CD282; toll-like receptor 2
K10160 TLR4, CD284; toll-like receptor 4
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K06856 IGH; immunoglobulin heavy chain
K05855 SYK; spleen tyrosine kinase [EC:2.7.10.2]
K06465 CD19; B-lymphocyte antigen CD19
K12230 PIK3AP1, BCAP; phosphoinositide 3-kinase adapter protein 1
K05438 GH; growth hormone
K05439 PRL; prolactin
K05418 OSM; oncostatin M
K05429 IL2; interleukin 2
K04736 IL3; interleukin 3
K05405 IL6; interleukin 6
K05430 IL4; interleukin 4
K05431 IL7; interleukin 7
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K05437 EPO; erythropoietin
K05423 CSF3, GCSF; granulocyte colony-stimulating factor
K05080 GHR; growth hormone receptor
K05081 PRLR; prolactin receptor
K05057 OSMR; oncostatin M receptor
K05068 IL2RA, CD25; interleukin 2 receptor alpha
K05069 IL2RB, CD122; interleukin 2 receptor beta
K05070 IL2RG, CD132; interleukin 2 receptor gamma
K04737 IL3RA, CD123; interleukin 3 receptor alpha
K05055 IL6R, CD126; interleukin 6 receptor
K05071 IL4R, CD124; interleukin 4 receptor
K05072 IL7R, CD127; interleukin 7 receptor
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K05079 EPOR; erythropoietin receptor
K05061 CSF3R, CD114; granulocyte colony-stimulating factor receptor
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K06236 COL1A; collagen type I alpha
K19719 COL2A; collagen type II alpha
K06237 COL4A; collagen type IV alpha
K06238 COL6A; collagen type VI alpha
K08131 COL9A; collagen type IX alpha
K05637 LAMA1_2; laminin, alpha 1/2
K06240 LAMA3_5; laminin, alpha 3/5
K06241 LAMA4; laminin, alpha 4
K05636 LAMB1; laminin, beta 1
K06243 LAMB2; laminin, beta 2
K06244 LAMB3; laminin, beta 3
K06245 LAMB4; laminin, beta 4
K05635 LAMC1; laminin, gamma 1
K06246 LAMC2; laminin, gamma 2
K06247 LAMC3; laminin, gamma 3
K06248 CHAD; chondroadherin
K06249 RELN; reelin [EC:3.4.21.-]
K16857 THBS1; thrombospondin 1
K04659 THBS2S; thrombospondin 2/3/4/5
K05717 FN1; fibronectin 1
K06250 SPP1, BNSP, OPN; secreted phosphoprotein 1
K06251 VTN; vitronectin
K06252 TN; tenascin
K03900 VWF; von Willebrand factor
K06253 IBSP; integrin binding sialoprotein
K06480 ITGA1, CD49a; integrin alpha 1
K06481 ITGA2, CD49b; integrin alpha 2
K06476 ITGA2B, CD41; integrin alpha 2B
K06482 ITGA3, CD49c; integrin alpha 3
K06483 ITGA4, CD49d; integrin alpha 4
K06484 ITGA5, CD49e; integrin alpha 5
K06485 ITGA6, CD49f; integrin alpha 6
K06583 ITGA7; integrin alpha 7
K06584 ITGA8; integrin alpha 8
K06585 ITGA9; integrin alpha 9
K06586 ITGA10; integrin alpha 10
K06587 ITGA11; integrin alpha 11
K06487 ITGAV, CD51; integrin alpha V
K05719 ITGB1, CD29; integrin beta 1
K06493 ITGB3, CD61; integrin beta 3
K06525 ITGB4, CD104; integrin beta 4
K06588 ITGB5; integrin beta 5
K06589 ITGB6; integrin beta 6
K06590 ITGB7; integrin beta 7
K06591 ITGB8; integrin beta 8
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K03914 F2R, PAR1; coagulation factor II (thrombin) receptor
K04129 CHRM1; muscarinic acetylcholine receptor M1
K04130 CHRM2; muscarinic acetylcholine receptor M2
K04289 LPAR1, EDG2; lysophosphatidic acid receptor 1
K04291 LPAR2, EDG4; lysophosphatidic acid receptor 2
K04294 LPAR3, EDG7; lysophosphatidic acid receptor 3
K04275 LPAR4, GPR23; lysophosphatidic acid receptor 4
K08390 LPAR5, GPR92; lysophosphatidic acid receptor 5
K04273 LPAR6, P2RY5; lysophosphatidic acid receptor 6
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K21289 PIK3CG; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma [EC:2.7.1.153]
K21290 PIK3R5_6; phosphoinositide-3-kinase regulatory subunit 5/6
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K07298 STK11, LKB1; serine/threonine-protein kinase 11 [EC:2.7.11.1]
K07198 PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K08270 DDIT4, REDD1; DNA-damage-inducible transcript 4
K07206 TSC1; tuberous sclerosis 1
K07207 TSC2; tuberous sclerosis 2
K07208 RHEB; Ras homolog enriched in brain
K08266 MLST8, GBL; target of rapamycin complex subunit LST8
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K07204 RAPTOR; regulatory associated protein of mTOR
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K03259 EIF4E; translation initiation factor 4E
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K03258 EIF4B; translation initiation factor 4B
K02991 RP-S6e, RPS6; small subunit ribosomal protein S6e
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K06071 PKN1; serine/threonine-protein kinase N1 [EC:2.7.11.13]
K23691 PKN2; serine/threonine-protein kinase N2 [EC:2.7.11.13]
K23692 PKN3; serine/threonine-protein kinase N3 [EC:2.7.11.13]
K13302 SGK1; serum/glucocorticoid-regulated kinase 1 [EC:2.7.11.1]
K13303 SGK2; serum/glucocorticoid-regulated kinase 2 [EC:2.7.11.1]
K13304 SGK3; serum/glucocorticoid-regulated kinase 3 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K05631 AIP3, WWP3, BAIAP1; atrophin-1 interacting protein 3 (BAI1-associated protein 1)
K05629 AIP1; atrophin-1 interacting protein 1
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K16339 THEM4, CTMP; acyl-coenzyme A thioesterase THEM4 [EC:3.1.2.2]
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K04079 HSP90A, htpG; molecular chaperone HtpG
K09487 HSP90B, TRA1; heat shock protein 90kDa beta
K09554 CDC37; cell division cycle protein 37
K16333 CRTC2, TORC2; CREB-regulated transcription coactivator 2
K16340 PHLPP; PH domain and leucine-rich repeat-containing protein phosphatase [EC:3.1.3.16]
K10167 TCL1A; T-cell leukemia/lymphoma 1A
K16836 TCL1B; T-cell leukemia/lymphoma 1B
K16837 MTCP1; mature T-cell proliferation-1 type B1
K13242 NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K00693 GYS; glycogen synthase [EC:2.4.1.11]
K01596 E4.1.1.32, pckA, PCK; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; G1/S-specific cyclin-D1
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K06624 CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K06626 CCNE; G1/S-specific cyclin-E1
K09408 FOXO3; forkhead box protein O3
K16332 RBL2; retinoblastoma-like protein 2
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K16341 BCL2L11, BIM; Bcl-2-like protein 11
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K06630 YWHAE; 14-3-3 protein epsilon
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K02158 BAD; Bcl-2-antagonist of cell death
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K02161 BCL2; apoptosis regulator Bcl-2
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
K02539 MCL1; myeloid leukemia cell differntiation protein MCL-1
K08524 RXRA, NR2B1; retinoid X receptor alpha
K04465 NR4A1, HMR; nuclear receptor subfamily 4 group A member 1
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K04735 RELA; transcription factor p65
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K09420 MYB, C-MYB; transcriptional activator Myb
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53, P53; tumor protein p53
|
04152 AMPK signaling pathway [PATH:ko04152]
|
04150 mTOR signaling pathway [PATH:ko04150]
|
04075 Plant hormone signal transduction [PATH:ko04075]
|
|
09133 Signaling molecules and interaction
|
04080 Neuroactive ligand-receptor interaction [PATH:ko04080]
|
04060 Cytokine-cytokine receptor interaction [PATH:ko04060]
|
K05514 CCL1; C-C motif chemokine 1
K13072 CCL25; C-C motif chemokine 25
K05512 CCL19, ELC; C-C motif chemokine 19
K16062 CCL21, SLC; C-C motif chemokine 21
K05408 CCL3; C-C motif chemokine 3
K12964 CCL4; C-C motif chemokine 4
K21083 CCL17; C-C motif chemokine 17
K21095 CCL22; C-C motif chemokine 22
K12499 CCL5; C-C motif chemokine 5
K16596 CCL8; C-C motif chemokine 8
K22671 CCL9; C-C motif chemokine 9
K21092 CCL14; C-C motif chemokine 14
K21093 CCL16; C-C motif chemokine 16
K05511 CCL15_23; C-C motif chemokine 15/23
K16595 CCL13; C-C motif chemokine 13
K05510 CCL6; C-C motif chemokine 6
K05509 CCL7; C-C motif chemokine 7
K14624 CCL2, MCP1; C-C motif chemokine 2
K16597 CCL11; C-C motif chemokine 11
K21097 CCL24; C-C motif chemokine 24
K21096 CCL26; C-C motif chemokine 26
K16598 CCL27; C-C motif chemokine 27
K05513 CCL28; C-C motif chemokine 28
K21094 CCL18; C-C motif chemokine 18
K14625 CCL20; C-C motif chemokine 20
K05505 CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
K05506 CXCL5_6, SCYB5_6; C-X-C motif chemokine 5/6
K10030 IL8, CXCL8; interleukin 8
K10029 PPBP, CXCL7; platelet basic protein
K05407 PF4, CXCL4; platelet factor 4
K05416 CXCL9; C-X-C motif chemokine 9
K12671 CXCL10, IP10; C-X-C motif chemokine 10
K12672 CXCL11, I-TAC; C-X-C motif chemokine 11
K10032 CXCL13; C-X-C motif chemokine 13
K10031 CXCL12; C-X-C motif chemokine 12
K10035 CXCL16; C-X-C motif chemokine 16
K10033 CXCL14, SCYB14; C-X-C motif chemokine 14
K10034 CXCL15; C-X-C motif chemokine 15
K22627 CXCL17; C-X-C motif chemokine 17
K05507 XCL1, SCM1; C motif chemokine 1
K22675 XCL2, SCM1B; C motif chemokine 2
K05508 CX3CL1, NTT; C-X3-C motif chemokine 1
K05429 IL2; interleukin 2
K05430 IL4; interleukin 4
K05431 IL7; interleukin 7
K05432 IL9; interleukin 9
K05433 IL15; interleukin 15
K05434 IL21; interleukin 21
K05436 TSLP; thymic stromal lymphopoietin
K04736 IL3; interleukin 3
K05428 IL5; interleukin 5
K05427 CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
K05435 IL13; interleukin 13
K05437 EPO; erythropoietin
K05438 GH; growth hormone
K05439 PRL; prolactin
K06854 THPO; thrombopoietin
K05423 CSF3, GCSF; granulocyte colony-stimulating factor
K05424 LEP; leptin
K05405 IL6; interleukin 6
K05417 IL11; interleukin 11
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05426 IL23A; interleukin 23 subunit alpha
K22629 IL27, IL27A; interleukin-27 subunit alpha
K22631 IL31; interleukin 31
K05421 CLCF1, BSF3, CLC; cardiotrophin-like cytokine factor 1
K05420 CNTF; ciliary neurotrophic factor
K05422 CTF1, CT1; cardiotrophin 1
K24382 CTF2; cardiotrophin 2
K05419 LIF; leukemia inhibitory factor
K05418 OSM; oncostatin M
K05443 IL10, CSIF; interleukin 10
K05444 IL19; interleukin 19
K22667 IL20; interleukin 20
K22668 IL24; interleukin 24
K05445 IL22, IL-TIF; interleukin 22
K05446 IL26; interleukin 26
K22669 IFNL2_3, IL28; interferon lambda 2/3
K05447 IFNL1, IL29; interferon lambda 1
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K05440 IFNW; interferon omega
K05441 IFNK; interferon kappa
K05442 IFNE; interferon epsilon
K04687 IFNG; interferon gamma
K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
K05481 IL1RN, IL1F3; interleukin 1 receptor antagonist
K05483 IL36RN, IL1F5; interleukin 36 receptor antagonist protein
K05484 IL36A, IL1F6; interleukin 36 alpha
K05486 IL36B, IL1F8; interleukin 36 beta
K05487 IL36G, IL1F9; interleukin 36 gamma
K05488 IL1F10, FKSG75; interleukin 1 family member 10
K05485 IL37, IL1F7; interleukin 37
K05482 IL18, IL1F4; interleukin 18
K12967 IL33; interleukin 33
K05489 IL17A, CTLA8; interleukin 17A
K05494 IL17F, ML1; interleukin 17F
K05490 IL17B, CX1; interleukin 17B
K05491 IL17C, CX2; interleukin 17C
K05492 IL17D, IL27; interleukin 17D
K05493 IL17E, IL25; interleukin 17E
K22628 IL16; interleukin 16
K22632 IL32; interleukin 32
K22633 IL34; interleukin 34
K05453 CSF1, MCSF; macrophage colony-stimulating factor 1
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K05468 LTA, TNFB; lymphotoxin alpha (TNF superfamily, member 1)
K03157 LTB, TNFC; lymphotoxin beta (TNF superfamily, member 3)
K05477 TNFSF14, LIGHT, CD258; tumor necrosis factor ligand superfamily member 14
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K05478 TNFSF15, VEGI; tumor necrosis factor ligand superfamily member 15
K04721 TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
K05480 EDA; ectodysplasin-A
K05451 NGFA; nerve growth factor, alpha
K02582 NGFB; nerve growth factor, beta
K05473 TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
K05474 TNFSF12, TWEAK; tumor necrosis factor ligand superfamily member 12
K05470 TNFSF7, CD70; tumor necrosis factor ligand superfamily member 7
K05471 TNFSF8, CD153; tumor necrosis factor ligand superfamily member 8
K03161 TNFSF5, CD40L, CD154; tumor necrosis factor ligand superfamily member 5
K05472 TNFSF9, CD137L; tumor necrosis factor ligand superfamily member 9
K05469 TNFSF4, OX40L, CD252; tumor necrosis factor ligand superfamily member 4
K05479 TNFSF18, GITRL; tumor necrosis factor ligand superfamily member 18
K05475 TNFSF13, APRIL, CD256; tumor necrosis factor ligand superfamily member 13
K05476 TNFSF13B, TNFSF20, CD257; tumor necrosis factor ligand superfamily member 13B
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K05504 GDF15; growth differentiation factor 15
K05503 GDF2, BMP9; growth differentiation factor 2
K22670 BMP10; bone morphogenetic protein 10
K05500 INHA; inhibin, alpha
K05496 BMP3; bone morphogenetic protein 3
K22674 GDF10, BMP3B; growth differentiation factor 10
K22679 GDF11; growth differentiation factor 11
K05497 MSTN, GDF8; growth differentiation factor 8
K04667 INHBA; inhibin beta A chain
K22687 INHBB; inhibin beta B chain
K05495 GDF1; growth differentiation factor 1
K22672 GDF3; growth differentiation factor 3
K04666 NODAL; nodal
K22673 GDF9; growth differentiation factor 9
K22688 INHBC; inhibin beta C chain
K22689 INHBE; inhibin beta E chain
K04665 AMH; anti-mullerian hormone
K21283 BMP2; bone morphogenetic protein 2
K04662 BMP4; bone morphogenetic protein 4
K04664 GDF5; growth differentiation factor 5
K20012 GDF6; growth differentiation factor 6
K20013 GDF7; growth differentiation factor 7
K05498 BMP15, GDF9B; bone morphogenetic protein 15
K04663 BMP5; bone morphogenetic protein 5
K16620 BMP6; bone morphogenetic protein 6
K16621 BMP7; bone morphogenetic protein 7
K16622 BMP8; bone morphogenetic protein 8
K04183 CCR8, CDw198; C-C chemokine receptor type 8
K04184 CCR9, CDw199; C-C chemokine receptor type 9
K04186 ACKR4, CCRL1, CCR11; atypical chemokine receptor 4
K04182 CCR7, CD197; C-C chemokine receptor type 7
K04179 CCR4, CD194; C-C chemokine receptor type 4
K04180 CCR5, CD195; C-C chemokine receptor type 5
K04178 CCR3, CD193; C-C chemokine receptor type 3
K04177 CCR2, CD192; C-C chemokine receptor type 2
K04176 CCR1, CD191; C-C chemokine receptor type 1
K04185 CCR10; C-C chemokine receptor type 10
K04181 CCR6, CD196; C-C chemokine receptor type 6
K04175 CXCR1, IL8RA, CD181; C-X-C chemokine receptor type 1
K05050 CXCR2, IL8RB, CD182; C-X-C chemokine receptor type 2
K04188 CXCR3, GPR9, CD183; C-X-C chemokine receptor type 3
K04190 CXCR5, BLR1, CD185; C-X-C chemokine receptor type 5
K04189 CXCR4, CD184; C-X-C chemokine receptor type 4
K04304 CXCR7, ACKR3, RDC1; C-X-C chemokine receptor type 7 (atypical chemokine receptor 3)
K04191 CXCR6, CD186; C-X-C chemokine receptor type 6
K04193 XCR1; XC chemokine receptor 1
K04192 CX3CR1; CX3C chemokine receptor 1
K05068 IL2RA, CD25; interleukin 2 receptor alpha
K05069 IL2RB, CD122; interleukin 2 receptor beta
K05070 IL2RG, CD132; interleukin 2 receptor gamma
K05071 IL4R, CD124; interleukin 4 receptor
K05072 IL7R, CD127; interleukin 7 receptor
K05073 IL9R, CD129; interleukin 9 receptor
K05074 IL15RA, CD215; interleukin 15 receptor alpha
K05075 IL21R, CD360; interleukin 21 receptor
K05078 TSLPR; thymic stromal-derived lymphopoietin receptor
K04737 IL3RA, CD123; interleukin 3 receptor alpha
K04738 CSF2RB, IL3RB, CD131; cytokine receptor common subunit beta
K05067 IL5RA. CD125; interleukin 5 receptor alpha
K05066 CSF2RA, GMCSFR, CD116; granulocyte-macrophage colony-stimulating factor receptor alpha
K05076 IL13RA1, CD213A1; interleukin 13 receptor alpha-1
K05077 IL13RA2, CD213A2; interleukin 13 receptor alpha-2
K05079 EPOR; erythropoietin receptor
K05080 GHR; growth hormone receptor
K05081 PRLR; prolactin receptor
K05082 TPOR, MPL, CD110; thrombopoietin receptor
K05061 CSF3R, CD114; granulocyte colony-stimulating factor receptor
K05062 LEPR, CD295; leptin receptor
K05055 IL6R, CD126; interleukin 6 receptor
K05060 IL6ST, GP130, CD130; interleukin 6 signal transducer
K05056 IL11RA; interleukin 11 receptor alpha
K05063 IL12RB1, CD212; interleukin 12 receptor beta-1
K05064 IL12RB2; interleukin 12 receptor beta-2
K05065 IL23R; interleukin 23 receptor
K19598 IL27RA; interleukin 27 receptor alpha
K22630 IL31RA; interleukin 31 receptor subunit alpha
K05059 CNTFR; ciliary neurotrophic factor receptor
K05058 LIFR, CD118; leukemia inhibitory factor receptor
K05057 OSMR; oncostatin M receptor
K05134 IL10RA, CD210A; interleukin 10 receptor alpha
K05135 IL10RB, CD210B; interleukin 10 receptor beta
K05136 IL20RA; interleukin 20 receptor alpha
K05137 IL20RB; interleukin 20 receptor beta
K05138 IL22RA1; interleukin 22 receptor alpha 1
K05140 IFNLR1, IL28RA; interferon lambda receptor 1
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K05132 IFNGR1, CD119; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K04386 IL1R1, CD121a; interleukin 1 receptor type I
K04723 IL1RAP; interleukin 1 receptor accessory protein
K04387 IL1R2, CD121b; interleukin 1 receptor type II
K05172 IL1RL2, IL1RRP2; interleukin 1 receptor-like 2
K05173 IL18R1, IL1RRP, CD218a; interleukin 18 receptor 1
K05174 IL18RAP, ACPL, CD218b; interleukin 18 receptor accessory protein
K05171 IL1RL1, ST2; interleukin 1 receptor-like 1
K05164 IL17RA, CD217; interleukin 17 receptor A
K05166 IL17RC, IL17RL; interleukin 17 receptor C
K05165 IL17RB, IL17RH1; interleukin 17 receptor B
K05168 IL17RE; interleukin 17 receptor E
K06454 CD4; T-cell surface glycoprotein CD4
K05090 CSF1R, FMS, CD115; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K05141 TNFRSF1B, TNFR2, CD120b; tumor necrosis factor receptor superfamily member 1B
K03159 TNFRSF3, LTBR; lymphotoxin beta receptor TNFR superfamily member 3
K05152 TNFRSF14, HVEM, CD270; tumor necrosis factor receptor superfamily member 14
K05143 TNFRSF6B, DCR3; tumor necrosis factor receptor superfamily member 6B
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K05160 TNFRSF25; tumor necrosis factor receptor superfamily member 25
K04722 TNFRSF10A_B, TRAILR1_2, DR4_5, CD261_2; tumor necrosis factor receptor superfamily member 10A/B
K22701 TNFRSF10C, TRAILR3, DCR1, CD263; tumor necrosis factor receptor superfamily member 10C
K22702 TNFRSF10D, TRAILR4, DCR2, CD264; tumor necrosis factor receptor superfamily member 10D
K05157 TNFRSF21, DR6, CD358; tumor necrosis factor receptor superfamily member 21
K05162 EDAR; tumor necrosis factor receptor superfamily member EDAR
K05163 EDA2R, TNFRSF27, XEDAR; tumor necrosis factor receptor superfamily member 27
K02583 NGFR, TNFRSF16, CD271; tumor necrosis factor receptor superfamily member 16
K05148 TNFRSF11B, OPG; tumor necrosis factor receptor superfamily member 11B
K05147 TNFRSF11A, RANK, CD265; tumor necrosis factor receptor superfamily member 11A
K05149 TNFRSF12A, FN14, TWEAKR, CD266; tumor necrosis factor receptor superfamily member 12A
K05144 TNFRSF7, CD27; tumor necrosis factor receptor superfamily member 7
K05145 TNFRSF8, CD30; tumor necrosis factor receptor superfamily member 8
K03160 TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
K05146 TNFRSF9, CD137; tumor necrosis factor receptor superfamily member 9
K05142 TNFRSF4, OX40, CD134; tumor necrosis factor receptor superfamily member 4
K05154 TNFRSF18, GITR, CD357; tumor necrosis factor receptor superfamily member 18
K05153 TNFRSF17, BCMA, CD269; tumor necrosis factor receptor superfamily member 17
K05150 TNFRSF13B, TACI, CD267; tumor necrosis factor receptor superfamily member 13B
K05151 TNFRSF13C, BAFFR, CD268; tumor necrosis factor receptor superfamily member 13C
K05155 TNFRSF19, TROY; tumor necrosis factor receptor superfamily member 19
K05156 TNFRSF19L, RELT; tumor necrosis factor receptor superfamily member 19-like
K04674 TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K13594 ACVRL1, ALK1; activin receptor-like kinase 1 [EC:2.7.11.30]
K04670 ACVR2A; activin receptor type-2A [EC:2.7.11.30]
K04671 BMPR2; bone morphogenetic protein receptor type-2 [EC:2.7.11.30]
K13596 ACVR2B; activin receptor type-2B [EC:2.7.11.30]
K13567 ACVR1B, ALK4; activin receptor type-1B [EC:2.7.11.30]
K13568 ACVR1C, ALK7; activin receptor type-1C [EC:2.7.11.30]
K04675 ACVR1, ALK2; activin receptor type-1 [EC:2.7.11.30]
K04672 AMHR2; anti-mullerian hormone receptor type-2 [EC:2.7.11.30]
K04673 BMPR1A, ALK3, CD292; bone morphogenetic protein receptor type-1A [EC:2.7.11.30]
K13578 BMPR1B, ALK6, CDw293; bone morphogenetic protein receptor type-1B [EC:2.7.11.30]
|
04061 Viral protein interaction with cytokine and cytokine receptor [PATH:ko04061]
|
K23381 vCCI; Poxvirus chemokine inhibitor
K22784 UL22A; HCMV glycoprotein UL22A
K23382 gG; Simplexvirus envelope glycoprotein G
K21538 vTNFR2; Poxvirus tumor necrosis factor receptor II
K23391 MC053L, MC054L; MOCV1 interleukin 18 binding protein
K22973 BARF1; EBV secreted protein BARF1
K12499 CCL5; C-C motif chemokine 5
K05408 CCL3; C-C motif chemokine 3
K16596 CCL8; C-C motif chemokine 8
K22671 CCL9; C-C motif chemokine 9
K21092 CCL14; C-C motif chemokine 14
K21093 CCL16; C-C motif chemokine 16
K05511 CCL15_23; C-C motif chemokine 15/23
K16595 CCL13; C-C motif chemokine 13
K05510 CCL6; C-C motif chemokine 6
K05509 CCL7; C-C motif chemokine 7
K21657 K4; KSHV macrophage inflammatory protein 2
K22624 vCCL27; MOCV1 CC chemokine receptor antagonist
K23392 vCCL4a, U83; HHV6 CCRs chemokine agonist
K21040 vCCL4b, U83; HHV6 CCR2 chemokine agonist
K14624 CCL2, MCP1; C-C motif chemokine 2
K16598 CCL27; C-C motif chemokine 27
K16597 CCL11; C-C motif chemokine 11
K21097 CCL24; C-C motif chemokine 24
K21096 CCL26; C-C motif chemokine 26
K05513 CCL28; C-C motif chemokine 28
K21083 CCL17; C-C motif chemokine 17
K21095 CCL22; C-C motif chemokine 22
K21658 K4.1; KSHV protein vCCL3
K12964 CCL4; C-C motif chemokine 4
K21659 K6; KSHV protein K6
K19287 gp160; HIV-1 envelope glycoprotein gp160
K14625 CCL20; C-C motif chemokine 20
K05514 CCL1; C-C motif chemokine 1
K13072 CCL25; C-C motif chemokine 25
K21094 CCL18; C-C motif chemokine 18
K05512 CCL19, ELC; C-C motif chemokine 19
K16062 CCL21, SLC; C-C motif chemokine 21
K05505 CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
K05506 CXCL5_6, SCYB5_6; C-X-C motif chemokine 5/6
K10030 IL8, CXCL8; interleukin 8
K21046 UL146; HCMV chemokine vCXCL1
K10029 PPBP, CXCL7; platelet basic protein
K05407 PF4, CXCL4; platelet factor 4
K05416 CXCL9; C-X-C motif chemokine 9
K12671 CXCL10, IP10; C-X-C motif chemokine 10
K12672 CXCL11, I-TAC; C-X-C motif chemokine 11
K10032 CXCL13; C-X-C motif chemokine 13
K10031 CXCL12; C-X-C motif chemokine 12
K10033 CXCL14, SCYB14; C-X-C motif chemokine 14
K05507 XCL1, SCM1; C motif chemokine 1
K22675 XCL2, SCM1B; C motif chemokine 2
K05508 CX3CL1, NTT; C-X3-C motif chemokine 1
K05443 IL10, CSIF; interleukin 10
K21533 vIL10; EBV viral interleukin 10
K05405 IL6; interleukin 6
K21670 vIL6, K2; KSHV interleukin 6
K05429 IL2; interleukin 2
K23069 p12I; HTLV-1 accessory protein p12I
K05482 IL18, IL1F4; interleukin 18
K05485 IL37, IL1F7; interleukin 37
K05444 IL19; interleukin 19
K22667 IL20; interleukin 20
K22668 IL24; interleukin 24
K23426 134R; YLDV 134R protein
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K05468 LTA, TNFB; lymphotoxin alpha (TNF superfamily, member 1)
K05477 TNFSF14, LIGHT, CD258; tumor necrosis factor ligand superfamily member 14
K21807 E6; HPV protein E6
K23428 2L; TPV TNF binding protein 2L
K19264 gD; Simplexvirus envelope glycoprotein D
K04721 TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
K21049 UL141; Cytomegalovirus protein UL141
K22633 IL34; interleukin 34
K05453 CSF1, MCSF; macrophage colony-stimulating factor 1
K04176 CCR1, CD191; C-C chemokine receptor type 1
K22781 US28; HCMV envelope protein US28
K23431 HHV6-U12; HHV6 CC-chemokine receptor U12
K04177 CCR2, CD192; C-C chemokine receptor type 2
K23433 HHV6-U51; HHV6 G-protein coupled receptor homolog U51
K04178 CCR3, CD193; C-C chemokine receptor type 3
K04179 CCR4, CD194; C-C chemokine receptor type 4
K23432 HHV7-U12; HHV7 CC-chemokine receptor U12
K23434 HHV7-U51; HHV7 G-protein coupled receptor homolog U51
K04180 CCR5, CD195; C-C chemokine receptor type 5
K04181 CCR6, CD196; C-C chemokine receptor type 6
K04183 CCR8, CDw198; C-C chemokine receptor type 8
K21667 vGPCR; KSHV G-protein coupled receptor
K23427 7L; Poxvirus chemokine receptor 7L
K04184 CCR9, CDw199; C-C chemokine receptor type 9
K04186 ACKR4, CCRL1, CCR11; atypical chemokine receptor 4
K04185 CCR10; C-C chemokine receptor type 10
K04182 CCR7, CD197; C-C chemokine receptor type 7
K04175 CXCR1, IL8RA, CD181; C-X-C chemokine receptor type 1
K05050 CXCR2, IL8RB, CD182; C-X-C chemokine receptor type 2
K04188 CXCR3, GPR9, CD183; C-X-C chemokine receptor type 3
K04190 CXCR5, BLR1, CD185; C-X-C chemokine receptor type 5
K04189 CXCR4, CD184; C-X-C chemokine receptor type 4
K04304 CXCR7, ACKR3, RDC1; C-X-C chemokine receptor type 7 (atypical chemokine receptor 3)
K04193 XCR1; XC chemokine receptor 1
K04192 CX3CR1; CX3C chemokine receptor 1
K05134 IL10RA, CD210A; interleukin 10 receptor alpha
K05135 IL10RB, CD210B; interleukin 10 receptor beta
K05055 IL6R, CD126; interleukin 6 receptor
K05060 IL6ST, GP130, CD130; interleukin 6 signal transducer
K05068 IL2RA, CD25; interleukin 2 receptor alpha
K05069 IL2RB, CD122; interleukin 2 receptor beta
K05070 IL2RG, CD132; interleukin 2 receptor gamma
K05173 IL18R1, IL1RRP, CD218a; interleukin 18 receptor 1
K05174 IL18RAP, ACPL, CD218b; interleukin 18 receptor accessory protein
K05136 IL20RA; interleukin 20 receptor alpha
K05137 IL20RB; interleukin 20 receptor beta
K05138 IL22RA1; interleukin 22 receptor alpha 1
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K05141 TNFRSF1B, TNFR2, CD120b; tumor necrosis factor receptor superfamily member 1B
K03159 TNFRSF3, LTBR; lymphotoxin beta receptor TNFR superfamily member 3
K05152 TNFRSF14, HVEM, CD270; tumor necrosis factor receptor superfamily member 14
K04722 TNFRSF10A_B, TRAILR1_2, DR4_5, CD261_2; tumor necrosis factor receptor superfamily member 10A/B
K22701 TNFRSF10C, TRAILR3, DCR1, CD263; tumor necrosis factor receptor superfamily member 10C
K22702 TNFRSF10D, TRAILR4, DCR2, CD264; tumor necrosis factor receptor superfamily member 10D
K05090 CSF1R, FMS, CD115; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
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04512 ECM-receptor interaction [PATH:ko04512]
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04514 Cell adhesion molecules [PATH:ko04514]
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|
09140 Cellular Processes
|
|
09150 Organismal Systems
|
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09151 Immune system
|
04640 Hematopoietic cell lineage [PATH:ko04640]
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04610 Complement and coagulation cascades [PATH:ko04610]
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04611 Platelet activation [PATH:ko04611]
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04620 Toll-like receptor signaling pathway [PATH:ko04620]
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04624 Toll and Imd signaling pathway [PATH:ko04624]
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04621 NOD-like receptor signaling pathway [PATH:ko04621]
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04622 RIG-I-like receptor signaling pathway [PATH:ko04622]
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04623 Cytosolic DNA-sensing pathway [PATH:ko04623]
|
04625 C-type lectin receptor signaling pathway [PATH:ko04625]
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K10074 CLEC7A, DECTIN1, CD369; C-type lectin domain family 7 member A
K14957 LSP1; lymphocyte-specific protein 1
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K07831 MRAS; Ras-related protein M-Ras
K07829 RRAS; Ras-related protein R-Ras
K07830 RRAS2, TC21; Ras-related protein R-Ras2
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04735 RELA; transcription factor p65
K09253 RELB; transcription factor RelB
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K04519 IL1B; interleukin 1 beta
K05855 SYK; spleen tyrosine kinase [EC:2.7.10.2]
K07293 PTPN11; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K04466 MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K04469 NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K02183 CALM; calmodulin
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K04446 NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
K17334 NFATC4, NFAT3; nuclear factor of activated T-cells, cytoplasmic 4
K05429 IL2; interleukin 2
K05443 IL10, CSIF; interleukin 10
K12496 EGR2; early growth response protein 2
K12497 EGR3; early growth response protein 3
K11987 PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K06068 PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K12800 NLRP3, PYPAF1; NACHT, LRR and PYD domains-containing protein 3
K12799 PYCARD, ASC; apoptosis-associated speck-like protein containing a CARD
K01370 CASP1; caspase 1 [EC:3.4.22.36]
K12794 CARD9; caspase recruitment domain-containing protein 9
K07368 BCL10; B-cell CLL/lymphoma 10
K07369 MALT1; mucosa-associated lymphoid tissue lymphoma translocation protein 1 [EC:3.4.22.-]
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K05405 IL6; interleukin 6
K05426 IL23A; interleukin 23 subunit alpha
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K22517 CBLB; E3 ubiquitin-protein ligase CBL-B [EC:2.3.2.27]
K17514 CLEC6A, DECTIN2; C-type lectin domain family 6 member A
K07983 FCER1G; high affinity immunoglobulin epsilon receptor subunit gamma
K06563 CLEC4M, DC-SIGN2, CD209, CD299; C-type lectin domain family 4 member M
K07532 ARHGEF12, LARG; Rho guanine nucleotide exchange factor 12
K04513 RHOA; Ras homolog gene family, member A
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K14958 KSR1; kinase suppressor of Ras 1
K08862 PLK3, CNK; polo-like kinase 3 [EC:2.7.11.21]
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K07211 IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
K11220 STAT1; signal transducer and activator of transcription 1
K04693 IRF9, ISGF3G, P48; interferon regulatory factor 9
K11221 STAT2; signal transducer and activator of transcription 2
K05492 IL17D, IL27; interleukin 17D
K08601 CYLD, USLP2; ubiquitin carboxyl-terminal hydrolase CYLD [EC:3.4.19.12]
K09258 BCL3; B-cell CLL/lymphoma protein 3
K21083 CCL17; C-C motif chemokine 17
K21095 CCL22; C-C motif chemokine 22
K04443 MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
K10059 CLEC4E, MINCLE; C-type lectin domain family 4 member E
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K09444 IRF1; interferon regulatory factor 1
K10058 CLEC4D, MCL, CD368; C-type lectin domain family 4 member D
K10070 CLEC1B; C-type lectin domain family 1 member B
|
04650 Natural killer cell mediated cytotoxicity [PATH:ko04650]
|
04612 Antigen processing and presentation [PATH:ko04612]
|
04660 T cell receptor signaling pathway [PATH:ko04660]
|
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K06450 CD3D; T-cell surface glycoprotein CD3 delta chain
K06451 CD3E; T-cell surface glycoprotein CD3 epsilon chain
K06452 CD3G; T-cell surface glycoprotein CD3 gamma chain
K06453 CD3Z, CD247; CD3Z antigen, zeta polypeptide
K06454 CD4; T-cell surface glycoprotein CD4
K06458 CD8A; T-cell surface glycoprotein CD8 alpha chain
K06459 CD8B; T-cell surface glycoprotein CD8 beta chain
K06478 PTPRC, CD45; receptor-type tyrosine-protein phosphatase C [EC:3.1.3.48]
K05856 LCK; lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2]
K05703 FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
K07360 ZAP70; tyrosine-protein kinase ZAP-70 [EC:2.7.10.2]
K07361 LCP2; lymphocyte cytosolic protein 2
K07362 LAT; linker for activation of T cells
K07363 ITK; IL2-inducible T-cell kinase [EC:2.7.10.2]
K07364 TEC; tyrosine-protein kinase Tec [EC:2.7.10.2]
K07365 NCK1; NCK adaptor protein 1
K19862 NCK2, GRB4; NCK adaptor protein 2
K05730 VAV; guanine nucleotide exchange factor VAV
K07366 GRAP2, GADS; GRB2-related adaptor protein 2
K04364 GRB2; growth factor receptor-bound protein 2
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04410 PAK2; p21-activated kinase 2 [EC:2.7.11.1]
K05733 PAK3, MRX30; p21-activated kinase 3 [EC:2.7.11.1]
K05734 PAK4; p21-activated kinase 4 [EC:2.7.11.1]
K05736 PAK5, PAK7; p21-activated kinase 5 [EC:2.7.11.1]
K05735 PAK6; p21-activated kinase 6 [EC:2.7.11.1]
K04513 RHOA; Ras homolog gene family, member A
K04393 CDC42; cell division control protein 42
K12076 DLG1; disks large protein 1
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K04446 NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
K03099 SOS; son of sevenless
K04350 RASGRP1; RAS guanyl-releasing protein 1
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04379 FOS; proto-oncogene protein c-fos
K04448 JUN; transcription factor AP-1
K18052 PRKCQ; novel protein kinase C theta type [EC:2.7.11.13]
K07367 CARD11; caspase recruitment domain-containing protein 11
K07368 BCL10; B-cell CLL/lymphoma 10
K07369 MALT1; mucosa-associated lymphoid tissue lymphoma translocation protein 1 [EC:3.4.22.-]
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02581 NFKBIB; NF-kappa-B inhibitor beta
K05872 NFKBIE; NF-kappa-B inhibitor epsilon
K06470 CD28; CD28 antigen
K06713 ICOS, AILIM, CD278; inducible T-cell co-stimulator
K03161 TNFSF5, CD40L, CD154; tumor necrosis factor ligand superfamily member 5
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04415 MAP3K8, COT; mitogen-activated protein kinase kinase kinase 8 [EC:2.7.11.25]
K04466 MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K06744 PDCD1, PD1, CD279; programmed cell death protein 1
K06538 CTLA4, CD152; cytotoxic T-lymphocyte-associated protein 4
K05697 PTPN6, SHP-1; tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]
K22517 CBLB; E3 ubiquitin-protein ligase CBL-B [EC:2.3.2.27]
K05429 IL2; interleukin 2
K05430 IL4; interleukin 4
K05428 IL5; interleukin 5
K05443 IL10, CSIF; interleukin 10
K04687 IFNG; interferon gamma
K05427 CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
|
04658 Th1 and Th2 cell differentiation [PATH:ko04658]
|
K06051 DLL; delta
K20995 NOTCH3; Notch 3
K06061 MAML; mastermind
K06053 RBPSUH, RBPJK; recombining binding protein suppressor of hairless
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04687 IFNG; interferon gamma
K05132 IFNGR1, CD119; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11220 STAT1; signal transducer and activator of transcription 1
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05063 IL12RB1, CD212; interleukin 12 receptor beta-1
K05064 IL12RB2; interleukin 12 receptor beta-2
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
K11222 STAT4; signal transducer and activator of transcription 4
K10166 TBX21; T-box protein 21
K09279 RUNX3, AML2; runt-related transcription factor 3
K06752 MHC2; MHC class II antigen
K06454 CD4; T-cell surface glycoprotein CD4
K05856 LCK; lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2]
K06451 CD3E; T-cell surface glycoprotein CD3 epsilon chain
K06452 CD3G; T-cell surface glycoprotein CD3 gamma chain
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K06453 CD3Z, CD247; CD3Z antigen, zeta polypeptide
K06450 CD3D; T-cell surface glycoprotein CD3 delta chain
K07360 ZAP70; tyrosine-protein kinase ZAP-70 [EC:2.7.10.2]
K07362 LAT; linker for activation of T cells
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K04446 NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
K18052 PRKCQ; novel protein kinase C theta type [EC:2.7.11.13]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02581 NFKBIB; NF-kappa-B inhibitor beta
K05872 NFKBIE; NF-kappa-B inhibitor epsilon
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04379 FOS; proto-oncogene protein c-fos
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K05429 IL2; interleukin 2
K05068 IL2RA, CD25; interleukin 2 receptor alpha
K05069 IL2RB, CD122; interleukin 2 receptor beta
K05070 IL2RG, CD132; interleukin 2 receptor gamma
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K05430 IL4; interleukin 4
K05071 IL4R, CD124; interleukin 4 receptor
K11225 STAT6; signal transducer and activator of transcription 6
K17895 GATA3; GATA-binding protein 3
K05428 IL5; interleukin 5
K05435 IL13; interleukin 13
K09035 CMAF, MAF; transcription factor Maf
K06052 JAG1, CD339; jagged-1
K21635 JAG2; jagged-2
K02599 NOTCH1; Notch 1
K20994 NOTCH2; Notch 2
|
04659 Th17 cell differentiation [PATH:ko04659]
|
K04519 IL1B; interleukin 1 beta
K04386 IL1R1, CD121a; interleukin 1 receptor type I
K04723 IL1RAP; interleukin 1 receptor accessory protein
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K09445 IRF4; interferon regulatory factor 4
K13375 TGFB1; transforming growth factor beta-1
K04674 TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K05434 IL21; interleukin 21
K05075 IL21R, CD360; interleukin 21 receptor
K05070 IL2RG, CD132; interleukin 2 receptor gamma
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K05405 IL6; interleukin 6
K05055 IL6R, CD126; interleukin 6 receptor
K05060 IL6ST, GP130, CD130; interleukin 6 signal transducer
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K05426 IL23A; interleukin 23 subunit alpha
K05065 IL23R; interleukin 23 receptor
K05063 IL12RB1, CD212; interleukin 12 receptor beta-1
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K08534 NR1F3, RORC; RAR-related orphan receptor gamma
K08532 NR1F1, RORA; RAR-related orphan receptor alpha
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K04079 HSP90A, htpG; molecular chaperone HtpG
K09093 AHR; aryl hydrocarbon receptor
K05489 IL17A, CTLA8; interleukin 17A
K05494 IL17F, ML1; interleukin 17F
K05445 IL22, IL-TIF; interleukin 22
K06752 MHC2; MHC class II antigen
K06454 CD4; T-cell surface glycoprotein CD4
K05856 LCK; lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2]
K06451 CD3E; T-cell surface glycoprotein CD3 epsilon chain
K06452 CD3G; T-cell surface glycoprotein CD3 gamma chain
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K06453 CD3Z, CD247; CD3Z antigen, zeta polypeptide
K06450 CD3D; T-cell surface glycoprotein CD3 delta chain
K07360 ZAP70; tyrosine-protein kinase ZAP-70 [EC:2.7.10.2]
K07362 LAT; linker for activation of T cells
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K04446 NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
K18052 PRKCQ; novel protein kinase C theta type [EC:2.7.11.13]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02581 NFKBIB; NF-kappa-B inhibitor beta
K05872 NFKBIE; NF-kappa-B inhibitor epsilon
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04379 FOS; proto-oncogene protein c-fos
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K05430 IL4; interleukin 4
K05071 IL4R, CD124; interleukin 4 receptor
K11225 STAT6; signal transducer and activator of transcription 6
K17895 GATA3; GATA-binding protein 3
K08367 RUNX1, AML1; runt-related transcription factor 1
K05492 IL17D, IL27; interleukin 17D
K19598 IL27RA; interleukin 27 receptor alpha
K04687 IFNG; interferon gamma
K05132 IFNGR1, CD119; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K11220 STAT1; signal transducer and activator of transcription 1
K10166 TBX21; T-box protein 21
K05429 IL2; interleukin 2
K05068 IL2RA, CD25; interleukin 2 receptor alpha
K05069 IL2RB, CD122; interleukin 2 receptor beta
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K10163 FOXP3, IPEX; forkhead box P3
K08527 RARA, NR1B1; retinoic acid receptor alpha
K08524 RXRA, NR2B1; retinoid X receptor alpha
K08525 RXRB, NR2B2; retinoid X receptor beta
K08526 RXRG, NR2B3; retinoid X receptor gamma
|
04657 IL-17 signaling pathway [PATH:ko04657]
|
04662 B cell receptor signaling pathway [PATH:ko04662]
|
04664 Fc epsilon RI signaling pathway [PATH:ko04664]
|
04666 Fc gamma R-mediated phagocytosis [PATH:ko04666]
|
04670 Leukocyte transendothelial migration [PATH:ko04670]
|
04672 Intestinal immune network for IgA production [PATH:ko04672]
|
K05412 CD80; CD80 antigen
K05413 CD86; CD86 antigen
K06752 MHC2; MHC class II antigen
K06470 CD28; CD28 antigen
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K05429 IL2; interleukin 2
K05430 IL4; interleukin 4
K05428 IL5; interleukin 5
K05405 IL6; interleukin 6
K05443 IL10, CSIF; interleukin 10
K13375 TGFB1; transforming growth factor beta-1
K05475 TNFSF13, APRIL, CD256; tumor necrosis factor ligand superfamily member 13
K05476 TNFSF13B, TNFSF20, CD257; tumor necrosis factor ligand superfamily member 13B
K05150 TNFRSF13B, TACI, CD267; tumor necrosis factor receptor superfamily member 13B
K05153 TNFRSF17, BCMA, CD269; tumor necrosis factor receptor superfamily member 17
K05151 TNFRSF13C, BAFFR, CD268; tumor necrosis factor receptor superfamily member 13C
K06856 IGH; immunoglobulin heavy chain
K10989 AICDA, AID; activation-induced cytidine deaminase [EC:3.5.4.38]
K03160 TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
K03161 TNFSF5, CD40L, CD154; tumor necrosis factor ligand superfamily member 5
K06713 ICOS, AILIM, CD278; inducible T-cell co-stimulator
K06710 ICOSLG, ICOSL, CD275; inducible T-cell co-stimulator ligand
K04184 CCR9, CDw199; C-C chemokine receptor type 9
K06483 ITGA4, CD49d; integrin alpha 4
K06590 ITGB7; integrin beta 7
K10031 CXCL12; C-X-C motif chemokine 12
K04189 CXCR4, CD184; C-X-C chemokine receptor type 4
K05513 CCL28; C-C motif chemokine 28
K04185 CCR10; C-C chemokine receptor type 10
K13072 CCL25; C-C motif chemokine 25
K06779 MADCAM1; mucosal vascular addressin cell adhesion molecule 1
K03159 TNFRSF3, LTBR; lymphotoxin beta receptor TNFR superfamily member 3
K04466 MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
K05433 IL15; interleukin 15
K05074 IL15RA, CD215; interleukin 15 receptor alpha
K13073 PIGR; polymeric immunoglobulin receptor
|
04062 Chemokine signaling pathway [PATH:ko04062]
|
|
09152 Endocrine system
|
|
09153 Circulatory system
|
|
09154 Digestive system
|
|
09155 Excretory system
|
|
09156 Nervous system
|
|
09157 Sensory system
|
|
09158 Development and regeneration
|
|
09149 Aging
|
|
09159 Environmental adaptation
|
|
09160 Human Diseases
|
|
09161 Cancer: overview
|
05200 Pathways in cancer [PATH:ko05200]
|
K06765 DCC; deleted in colorectal carcinoma
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K08733 APPL1, DIP13A; DCC-interacting protein 13 alpha
K05689 CDH1, CDHE, CD324; cadherin 1, type 1, E-cadherin
K02105 CTNNB1; catenin beta 1
K05691 CTNNA; catenin alpha
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02085 APC; adenomatosis polyposis coli protein
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02620 TCF7, TCF-1; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K08731 BIRC5; baculoviral IAP repeat-containing protein 5
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; G1/S-specific cyclin-D1
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7, fz; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4, fz4, CD344; frizzled 4
K02375 FZD5_8, fz2; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10, CD349_50; frizzled 9/10
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K02353 DVL; segment polarity protein dishevelled
K03069 FRAT1; frequently rearranged in advanced T-cell lymphomas 1
K03096 FRAT2; frequently rearranged in advanced T-cell lymphomas 2
K01313 F2; coagulation factor II (thrombin) [EC:3.4.21.5]
K09821 AGT, SERPINA8; angiotensinogen
K03914 F2R, PAR1; coagulation factor II (thrombin) receptor
K04236 F2RL3, PAR4; coagulation factor II (thrombin) receptor-like 3
K04289 LPAR1, EDG2; lysophosphatidic acid receptor 1
K04291 LPAR2, EDG4; lysophosphatidic acid receptor 2
K04294 LPAR3, EDG7; lysophosphatidic acid receptor 3
K04275 LPAR4, GPR23; lysophosphatidic acid receptor 4
K08390 LPAR5, GPR92; lysophosphatidic acid receptor 5
K04273 LPAR6, P2RY5; lysophosphatidic acid receptor 6
K04166 AGTR1; angiotensin II receptor type 1
K04346 GNA12; guanine nucleotide-binding protein subunit alpha-12
K04639 GNA13; guanine nucleotide-binding protein subunit alpha-13
K07532 ARHGEF12, LARG; Rho guanine nucleotide exchange factor 12
K12331 ARHGEF11; Rho guanine nucleotide exchange factor 11
K12330 ARHGEF1; Rho guanine nucleotide exchange factor 1
K19464 PLEKHG5; pleckstrin homology domain-containing family G member 5
K04513 RHOA; Ras homolog gene family, member A
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K10031 CXCL12; C-X-C motif chemokine 12
K04189 CXCR4, CD184; C-X-C chemokine receptor type 4
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04258 PTGER1; prostaglandin E receptor 1
K04259 PTGER2; prostaglandin E receptor 2
K04260 PTGER3; prostaglandin E receptor 3
K04261 PTGER4; prostaglandin E receptor 4
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K06237 COL4A; collagen type IV alpha
K05637 LAMA1_2; laminin, alpha 1/2
K06240 LAMA3_5; laminin, alpha 3/5
K06241 LAMA4; laminin, alpha 4
K05636 LAMB1; laminin, beta 1
K06243 LAMB2; laminin, beta 2
K06244 LAMB3; laminin, beta 3
K06245 LAMB4; laminin, beta 4
K05635 LAMC1; laminin, gamma 1
K06246 LAMC2; laminin, gamma 2
K06247 LAMC3; laminin, gamma 3
K05717 FN1; fibronectin 1
K06481 ITGA2, CD49b; integrin alpha 2
K06476 ITGA2B, CD41; integrin alpha 2B
K06482 ITGA3, CD49c; integrin alpha 3
K06485 ITGA6, CD49f; integrin alpha 6
K06487 ITGAV, CD51; integrin alpha V
K05719 ITGB1, CD29; integrin beta 1
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K09348 NKX3-1; homeobox protein Nkx-3.1
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04469 NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
K04735 RELA; transcription factor p65
K11987 PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
K02161 BCL2; apoptosis regulator Bcl-2
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04725 XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K16061 BIRC7_8; baculoviral IAP repeat-containing protein 7/8
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K03172 TRAF1; TNF receptor-associated factor 1
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K03174 TRAF3; TNF receptor-associated factor 3
K09848 TRAF4; TNF receptor-associated factor 4
K09849 TRAF5; TNF receptor-associated factor 5
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K07201 FOXO1; forkhead box protein O1
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53, P53; tumor protein p53
K06624 CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K08878 BCR1, BCR; breakpoint cluster region protein [EC:2.7.11.1]
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K04438 CRK, CRKII; C-crk adapter molecule crk
K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K04702 PIM1; proto-oncogene serine/threonine-protein kinase Pim-1 [EC:2.7.11.1]
K08806 PIM2; proto-oncogene serine/threonine-protein kinase Pim-2 [EC:2.7.11.1]
K03898 KNG, BK; kininogen
K16366 EDN1; endothelin-1
K03915 BDKRB1; bradykinin receptor B1
K03916 BDKRB2; bradykinin receptor B2
K04197 EDNRA; endothelin receptor type A
K04198 EDNRB; endothelin receptor type B
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K05429 IL2; interleukin 2
K04736 IL3; interleukin 3
K05430 IL4; interleukin 4
K05428 IL5; interleukin 5
K05405 IL6; interleukin 6
K05431 IL7; interleukin 7
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05435 IL13; interleukin 13
K05433 IL15; interleukin 15
K05426 IL23A; interleukin 23 subunit alpha
K05437 EPO; erythropoietin
K05414 IFNA; interferon alpha
K04687 IFNG; interferon gamma
K05068 IL2RA, CD25; interleukin 2 receptor alpha
K05069 IL2RB, CD122; interleukin 2 receptor beta
K05070 IL2RG, CD132; interleukin 2 receptor gamma
K04737 IL3RA, CD123; interleukin 3 receptor alpha
K05071 IL4R, CD124; interleukin 4 receptor
K04738 CSF2RB, IL3RB, CD131; cytokine receptor common subunit beta
K05067 IL5RA. CD125; interleukin 5 receptor alpha
K05055 IL6R, CD126; interleukin 6 receptor
K05060 IL6ST, GP130, CD130; interleukin 6 signal transducer
K05072 IL7R, CD127; interleukin 7 receptor
K05063 IL12RB1, CD212; interleukin 12 receptor beta-1
K05064 IL12RB2; interleukin 12 receptor beta-2
K05076 IL13RA1, CD213A1; interleukin 13 receptor alpha-1
K05074 IL15RA, CD215; interleukin 15 receptor alpha
K05065 IL23R; interleukin 23 receptor
K05079 EPOR; erythropoietin receptor
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K05132 IFNGR1, CD119; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K15420 EML4; echinoderm microtubule-associated protein-like 4
K05119 ALK, CD246; anaplastic lymphoma kinase [EC:2.7.10.1]
K04350 RASGRP1; RAS guanyl-releasing protein 1
K12361 RASGRP2; RAS guanyl-releasing protein 2
K12362 RASGRP3; RAS guanyl-releasing protein 3
K12363 RASGRP4; RAS guanyl-releasing protein 4
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K11222 STAT4; signal transducer and activator of transcription 4
K11225 STAT6; signal transducer and activator of transcription 6
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K16859 PGF; placenta growth factor
K05449 VEGFC_D; vascular endothelial growth factor C/D
K08774 TGFA; transforming growth factor, alpha
K04357 EGF; epidermal growth factor
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2, HER2, CD340; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K04363 PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05459 IGF1; insulin-like growth factor 1
K13769 IGF2; insulin-like growth factor 2
K05087 IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K05461 KITLG; KIT ligand
K05091 KIT, SCFR, CD117; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K05454 FLT3LG; fms-related tyrosine kinase 3 ligand
K05092 FLT3, FLK2, CD135; fms-related tyrosine kinase 3 [EC:2.7.10.1]
K05460 HGF; hepatocyte growth factor
K05099 MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K04362 FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2, CD332; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3, CD333; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4, CD334; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04379 FOS; proto-oncogene protein c-fos
K02678 ETS1, pnt; C-ets-1
K01388 MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
K01398 MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K10030 IL8, CXCL8; interleukin 8
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K04445 RPS6KA5, MSK1; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
K05126 RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
K09288 CCDC6, PTC; coiled-coil domain-containing protein 6
K09289 NCOA4, PTC3; nuclear receptor coactivator 4
K03176 NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K09290 TPM3; tropomyosin 3
K09291 TPR, MLP1, MLP2; nucleoprotein TPR
K09292 TFG; protein TFG
K09850 RASSF1; Ras association domain-containing protein 1
K08015 RASSF5, RAPL; Ras association domain-containing protein 5
K04411 STK4, MST1; serine/threonine kinase 4
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K04375 ELK1; ETS domain-containing protein Elk-1
K02183 CALM; calmodulin
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K07834 RALA; Ras-related protein Ral-A
K07835 RALB; Ras-related protein Ral-B
K08773 RALBP1; RalA-binding protein 1
K04393 CDC42; cell division control protein 42
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K09293 PAX8; paired box protein 8
K08530 NR1C3, PPARG; peroxisome proliferator-activated receptor gamma
K08524 RXRA, NR2B1; retinoid X receptor alpha
K08525 RXRB, NR2B2; retinoid X receptor beta
K08526 RXRG, NR2B3; retinoid X receptor gamma
K08528 RARB, NR1B2; retinoic acid receptor beta
K08550 ESR1, NR3A1; estrogen receptor alpha
K08551 ESR2, NR3A2; estrogen receptor beta
K09101 NCOA1, SRC1, KAT13A; nuclear receptor coactivator 1 [EC:2.3.1.48]
K11256 NCOA3, ACTR, KAT13B; nuclear receptor coactivator 3 [EC:2.3.1.48]
K04684 SP1; transcription factor Sp1
K04504 NR1C2, PPARD; peroxisome proliferator-activated receptor delta
K10056 JUP; junction plakoglobin
K10055 ZBTB16, PLZF; zinc finger and BTB domain-containing protein 16
K08527 RARA, NR1B1; retinoic acid receptor alpha
K06627 CCNA; cyclin-A
K10054 PML, TRIM19; probable transcription factor PML
K08367 RUNX1, AML1; runt-related transcription factor 1
K10053 RUNX1T1, CBFA2T1; CBFA2/RNUX1 translocation partner 1
K09438 SPI1; transcription factor PU.1
K09055 CEBPA; CCAAT/enhancer binding protein (C/EBP), alpha
K05066 CSF2RA, GMCSFR, CD116; granulocyte-macrophage colony-stimulating factor receptor alpha
K05061 CSF3R, CD114; granulocyte colony-stimulating factor receptor
K05090 CSF1R, FMS, CD115; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K06621 CDKN2A, P16, INK4A; cyclin-dependent kinase inhibitor 2A
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04453 MAX; Max protein
K10500 ZBTB17, MIZ1; zinc finger and BTB domain-containing protein 17
K04685 CDKN2B, P15, INK4B; cyclin-dependent kinase inhibitor 2B
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K02219 CKS1; cyclin-dependent kinase regulatory subunit CKS1
K03094 SKP1, CBF3D; S-phase kinase-associated protein 1
K03347 CUL1, CDC53; cullin 1
K03868 RBX1, ROC1; RING-box protein 1 [EC:2.3.2.32]
K03875 SKP2, FBXL1; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06618 RB1; retinoblastoma-associated protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK, BAK1; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K11126 TERT, EST2; telomerase reverse transcriptase [EC:2.7.7.49]
K22183 TERC; telomerase RNA component
K09455 MITF; microphthalmia-associated transcription factor
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04462 MECOM, EVI1, PRDM3; [histone H3]-lysine9 N-methyltransferase (ecotropic virus integration site 1 protein) [EC:2.1.1.367]
K04496 CTBP; C-terminal binding protein
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K08734 MLH1; DNA mismatch repair protein MLH1
K08735 MSH2; DNA mismatch repair protein MSH2
K08736 MSH3; DNA mismatch repair protein MSH3
K08737 MSH6; DNA mismatch repair protein MSH6
K08775 BRCA2, FANCD1; breast cancer 2 susceptibility protein
K04482 RAD51; DNA repair protein RAD51
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K10131 PMAIP1, NOXA; phorbol-12-myristate-13-acetate-induced protein 1
K10132 BBC3, PUMA; Bcl-2-binding component 3
K16341 BCL2L11, BIM; Bcl-2-like protein 11
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04397 CASP7; caspase 7 [EC:3.4.22.60]
K10456 KLHL19, KEAP1, INRF2; kelch-like protein 19
K05638 NFE2L2, NRF2; nuclear factor erythroid 2-related factor 2
K00510 HMOX1; heme oxygenase 1 [EC:1.14.14.18]
K00355 NQO1; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]
K00799 GST, gst; glutathione S-transferase [EC:2.5.1.18]
K23790 GSTP; glutathione S-transferase P [EC:2.5.1.18]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K03871 VHL; von Hippel-Lindau disease tumor supressor
K03872 ELOC, TCEB1; elongin-C
K03873 ELOB, TCEB2; elongin-B
K03870 CUL2; cullin 2
K09592 EGLN, HPH; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K01679 E4.2.1.2B, fumC, FH; fumarate hydratase, class II [EC:4.2.1.2]
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K09095 HIF2A, EPAS1; hypoxia-inducible factor 2 alpha
K09097 ARNT; aryl hydrocarbon receptor nuclear translocator
K15589 ARNT2; aryl hydrocarbon receptor nuclear translocator 2
K04498 EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
K07299 SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
K06052 JAG1, CD339; jagged-1
K21635 JAG2; jagged-2
K06051 DLL; delta
K02599 NOTCH1; Notch 1
K20994 NOTCH2; Notch 2
K20995 NOTCH3; Notch 3
K20996 NOTCH4; Notch 4
K06054 HES1; hairy and enhancer of split 1
K06055 HES5; hairy and enhancer of split 5
K09091 HEY; hairy and enhancer of split related with YRPW motif
K05097 FLT4, VEGFR3; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K11988 SHH; sonic hedgehog
K06225 PTCH1; patched 1
K06226 SMO; smoothened
K18806 KIF7; kinesin family member 7
K06229 SUFU; suppressor of fused
K16797 GLI1; zinc finger protein GLI1
K16798 GLI2; zinc finger protein GLI2
K06230 GLI3; zinc finger protein GLI3
K21283 BMP2; bone morphogenetic protein 2
K04662 BMP4; bone morphogenetic protein 4
K06231 HHIP; hedgehog interacting protein
K11101 PTCH2; patched 2
K08557 AR, NR3C4; androgen receptor
K04079 HSP90A, htpG; molecular chaperone HtpG
K09487 HSP90B, TRA1; heat shock protein 90kDa beta
K01351 KLK3; semenogelase [EC:3.4.21.77]
|
05202 Transcriptional misregulation in cancer [PATH:ko05202]
|
05206 MicroRNAs in cancer [PATH:ko05206]
|
05205 Proteoglycans in cancer [PATH:ko05205]
|
05204 Chemical carcinogenesis [PATH:ko05204]
|
05203 Viral carcinogenesis [PATH:ko05203]
|
05230 Central carbon metabolism in cancer [PATH:ko05230]
|
05231 Choline metabolism in cancer [PATH:ko05231]
|
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer [PATH:ko05235]
|
|
09162 Cancer: specific types
|
|
09163 Immune disease
|
05310 Asthma [PATH:ko05310]
|
05322 Systemic lupus erythematosus [PATH:ko05322]
|
05323 Rheumatoid arthritis [PATH:ko05323]
|
05320 Autoimmune thyroid disease [PATH:ko05320]
|
K05414 IFNA; interferon alpha
K06752 MHC2; MHC class II antigen
K06538 CTLA4, CD152; cytotoxic T-lymphocyte-associated protein 4
K00431 TPO; thyroid peroxidase [EC:1.11.1.8]
K10809 TG; thyroglobulin
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K05412 CD80; CD80 antigen
K05413 CD86; CD86 antigen
K06470 CD28; CD28 antigen
K05429 IL2; interleukin 2
K06751 MHC1; MHC class I antigen
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K07818 PRF1; perforin 1
K01353 GZMB; granzyme B [EC:3.4.21.79]
K03161 TNFSF5, CD40L, CD154; tumor necrosis factor ligand superfamily member 5
K03160 TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
K05430 IL4; interleukin 4
K05428 IL5; interleukin 5
K05443 IL10, CSIF; interleukin 10
K06856 IGH; immunoglobulin heavy chain
K04249 TSHR; thyrotropin receptor
K08522 CGA; glycoprotein hormones alpha chain
K05251 TSHB; thyrotropin subunit beta
|
05321 Inflammatory bowel disease [PATH:ko05321]
|
K10159 TLR2, CD282; toll-like receptor 2
K10160 TLR4, CD284; toll-like receptor 4
K10168 TLR5; toll-like receptor 5
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K10165 NOD2, CARD15; nucleotide-binding oligomerization domain-containing protein 2
K06752 MHC2; MHC class II antigen
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K04687 IFNG; interferon gamma
K05132 IFNGR1, CD119; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K11220 STAT1; signal transducer and activator of transcription 1
K10166 TBX21; T-box protein 21
K05430 IL4; interleukin 4
K05428 IL5; interleukin 5
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05064 IL12RB2; interleukin 12 receptor beta-2
K05063 IL12RB1, CD212; interleukin 12 receptor beta-1
K11222 STAT4; signal transducer and activator of transcription 4
K05429 IL2; interleukin 2
K05482 IL18, IL1F4; interleukin 18
K05173 IL18R1, IL1RRP, CD218a; interleukin 18 receptor 1
K05174 IL18RAP, ACPL, CD218b; interleukin 18 receptor accessory protein
K04448 JUN; transcription factor AP-1
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K05405 IL6; interleukin 6
K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04692 STAT3; signal transducer and activator of transcription 3
K05434 IL21; interleukin 21
K05075 IL21R, CD360; interleukin 21 receptor
K05426 IL23A; interleukin 23 subunit alpha
K05065 IL23R; interleukin 23 receptor
K08534 NR1F3, RORC; RAR-related orphan receptor gamma
K08532 NR1F1, RORA; RAR-related orphan receptor alpha
K10163 FOXP3, IPEX; forkhead box P3
K05489 IL17A, CTLA8; interleukin 17A
K05494 IL17F, ML1; interleukin 17F
K05445 IL22, IL-TIF; interleukin 22
K05071 IL4R, CD124; interleukin 4 receptor
K05070 IL2RG, CD132; interleukin 2 receptor gamma
K11225 STAT6; signal transducer and activator of transcription 6
K17895 GATA3; GATA-binding protein 3
K05443 IL10, CSIF; interleukin 10
K05435 IL13; interleukin 13
K09035 CMAF, MAF; transcription factor Maf
K04446 NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
|
05330 Allograft rejection [PATH:ko05330]
|
K06751 MHC1; MHC class I antigen
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K05412 CD80; CD80 antigen
K05413 CD86; CD86 antigen
K06470 CD28; CD28 antigen
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K07818 PRF1; perforin 1
K01353 GZMB; granzyme B [EC:3.4.21.79]
K06752 MHC2; MHC class II antigen
K05429 IL2; interleukin 2
K03161 TNFSF5, CD40L, CD154; tumor necrosis factor ligand superfamily member 5
K03160 TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
K04687 IFNG; interferon gamma
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K05430 IL4; interleukin 4
K05428 IL5; interleukin 5
K05443 IL10, CSIF; interleukin 10
K06856 IGH; immunoglobulin heavy chain
|
05332 Graft-versus-host disease [PATH:ko05332]
|
K05405 IL6; interleukin 6
K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K06752 MHC2; MHC class II antigen
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K05412 CD80; CD80 antigen
K05413 CD86; CD86 antigen
K06470 CD28; CD28 antigen
K05429 IL2; interleukin 2
K06751 MHC1; MHC class I antigen
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K07818 PRF1; perforin 1
K01353 GZMB; granzyme B [EC:3.4.21.79]
K04687 IFNG; interferon gamma
K07981 KIR2DL1_2_3, CD158A_B; killer cell immunoglobulin-like receptor 2DL1/2/3
K24232 KIR2DL5, CD158F; killer cell immunoglobulin-like receptor 2DL5
K07980 KIR3DL, CD158; killer cell immunoglobulin-like receptor 3DL
K06541 KLRC1, NKG2A; killer cell lectin-like receptor subfamily C1
K06516 KLRD1, CD94; killer cell lectin-like receptor subfamily D member 1
|
05340 Primary immunodeficiency [PATH:ko05340]
|
|
09164 Neurodegenerative disease
|
|
09165 Substance dependence
|
|
09166 Cardiovascular disease
|
|
09167 Endocrine and metabolic disease
|
04930 Type II diabetes mellitus [PATH:ko04930]
|
04940 Type I diabetes mellitus [PATH:ko04940]
|
K04526 INS; insulin
K01580 E4.1.1.15, gadB, gadA, GAD; glutamate decarboxylase [EC:4.1.1.15]
K07817 PTPRN; receptor-type tyrosine-protein phosphatase N [EC:3.1.3.48]
K01294 CPE; carboxypeptidase E [EC:3.4.17.10]
K04077 groEL, HSPD1; chaperonin GroEL
K19863 ICA1; islet cell auto antigen 1
K06752 MHC2; MHC class II antigen
K05412 CD80; CD80 antigen
K05413 CD86; CD86 antigen
K06470 CD28; CD28 antigen
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05429 IL2; interleukin 2
K04687 IFNG; interferon gamma
K06751 MHC1; MHC class I antigen
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K07818 PRF1; perforin 1
K01353 GZMB; granzyme B [EC:3.4.21.79]
K05468 LTA, TNFB; lymphotoxin alpha (TNF superfamily, member 1)
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
|
04950 Maturity onset diabetes of the young [PATH:ko04950]
|
04932 Non-alcoholic fatty liver disease [PATH:ko04932]
|
04931 Insulin resistance [PATH:ko04931]
|
04933 AGE-RAGE signaling pathway in diabetic complications [PATH:ko04933]
|
04934 Cushing syndrome [PATH:ko04934]
|
|
09171 Infectious disease: bacterial
|
05110 Vibrio cholerae infection [PATH:ko05110]
|
05120 Epithelial cell signaling in Helicobacter pylori infection [PATH:ko05120]
|
05130 Pathogenic Escherichia coli infection [PATH:ko05130]
|
05132 Salmonella infection [PATH:ko05132]
|
05131 Shigellosis [PATH:ko05131]
|
05135 Yersinia infection [PATH:ko05135]
|
K13735 yeeJ; adhesin/invasin
K12341 yadA; adhesin YadA
K05717 FN1; fibronectin 1
K06483 ITGA4, CD49d; integrin alpha 4
K06484 ITGA5, CD49e; integrin alpha 5
K05719 ITGB1, CD29; integrin beta 1
K07863 RHOG; Ras homolog gene family, member G
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K05871 PTK2B, FAK2; focal adhesion kinase 2 [EC:2.7.10.2]
K04438 CRK, CRKII; C-crk adapter molecule crk
K05726 BCAR1, CAS; breast cancer anti-estrogen resistance 1
K12366 ELMO1, CED12; engulfment and cell motility protein 1
K18985 ELMO2, CED12A; engulfment and cell motility protein 2
K13708 DOCK1; dedicator of cytokinesis protein 1
K06856 IGH; immunoglobulin heavy chain
K06472 FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
K07941 ARF6; ADP-ribosylation factor 6
K23612 WASL; neural Wiskott-Aldrich syndrome protein
K17260 ACTR2, ARP2; actin-related protein 2
K18584 ACTR3, ARP3; actin-related protein 3
K05757 ARPC1A_B; actin related protein 2/3 complex, subunit 1A/1B
K05758 ARPC2; actin related protein 2/3 complex, subunit 2
K05756 ARPC3; actin related protein 2/3 complex, subunit 3
K05755 ARPC4; actin related protein 2/3 complex, subunit 4
K05754 ARPC5; actin related protein 2/3 complex, subunit 5
K05692 ACTB_G1; actin beta/gamma 1
K19475 WIPF; WAS/WASL-interacting protein
K05627 BAIAP2, IRSP53; BAI1-associated protein 2
K05748 WASF2; WAS protein family, member 2
K05760 PXN; paxillin
K12487 GIT2; G protein-coupled receptor kinase interactor 2
K13710 ARHGEF7, PIXB; Rho guanine nucleotide exchange factor 7
K04393 CDC42; cell division control protein 42
K05747 WAS; Wiskott-Aldrich syndrome protein
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K07532 ARHGEF12, LARG; Rho guanine nucleotide exchange factor 12
K12330 ARHGEF1; Rho guanine nucleotide exchange factor 1
K21072 ARHGEF28; A-kinase anchor protein 28
K04513 RHOA; Ras homolog gene family, member A
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K17698 FYB, ADAP; FYN binding protein
K23471 SKAP2; src kinase-associated phosphoprotein 2
K23472 ypkA, yopO; serine/threonine protein kinase YpkA [EC:2.7.11.1]
K08599 yopT; YopT peptidase [EC:3.4.22.-]
K23473 yopE; outer membrane virulence protein YopE
K23474 yopH; tyrosine-protein phosphatase YopH [EC:3.1.3.48]
K23475 yopB, popB, aopB; transloator
K23476 yopD, popD, aopD; transloator
K12800 NLRP3, PYPAF1; NACHT, LRR and PYD domains-containing protein 3
K12805 NLRC4, CARD12; NLR family CARD domain-containing protein 4
K06071 PKN1; serine/threonine-protein kinase N1 [EC:2.7.11.13]
K23691 PKN2; serine/threonine-protein kinase N2 [EC:2.7.11.13]
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K12803 MEFV; pyrin
K05743 LIMK1; LIM domain kinase 1 [EC:2.7.11.1]
K12799 PYCARD, ASC; apoptosis-associated speck-like protein containing a CARD
K01370 CASP1; caspase 1 [EC:3.4.22.36]
K05482 IL18, IL1F4; interleukin 18
K04519 IL1B; interleukin 1 beta
K23477 yopQ, yopK; protein YopQ
K23478 yopM; outer membrane protein YopM
K10160 TLR4, CD284; toll-like receptor 4
K04729 MYD88; myeloid differentiation primary response protein MyD88
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K04403 MAP3K7IP1, TAB1; TAK1-binding protein 1
K04404 MAP3K7IP2, TAB2; TAK1-binding protein 2
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04432 MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04430 MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04379 FOS; proto-oncogene protein c-fos
K04448 JUN; transcription factor AP-1
K05842 TRIF; toll-like receptor adapter molecule 1
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K05411 IRF3; interferon regulatory factor 3
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K05405 IL6; interleukin 6
K10030 IL8, CXCL8; interleukin 8
K05415 IFNB; interferon beta
K08598 yopJ; YopJ protease family
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K14624 CCL2, MCP1; C-C motif chemokine 2
K06454 CD4; T-cell surface glycoprotein CD4
K06458 CD8A; T-cell surface glycoprotein CD8 alpha chain
K06459 CD8B; T-cell surface glycoprotein CD8 beta chain
K05856 LCK; lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2]
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K07360 ZAP70; tyrosine-protein kinase ZAP-70 [EC:2.7.10.2]
K07362 LAT; linker for activation of T cells
K07361 LCP2; lymphocyte cytosolic protein 2
K05730 VAV; guanine nucleotide exchange factor VAV
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K04446 NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
K05429 IL2; interleukin 2
K05443 IL10, CSIF; interleukin 10
|
05133 Pertussis [PATH:ko05133]
|
05134 Legionellosis [PATH:ko05134]
|
05150 Staphylococcus aureus infection [PATH:ko05150]
|
05152 Tuberculosis [PATH:ko05152]
|
05100 Bacterial invasion of epithelial cells [PATH:ko05100]
|
|
09172 Infectious disease: viral
|
05166 Human T-cell leukemia virus 1 infection [PATH:ko05166]
|
K19259 env; HTLV envelope glycoprotein gp62
K07299 SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
K06724 NRP1, CD304; neuropilin 1
K04377 MYC; Myc proto-oncogene protein
K08874 TRRAP; transformation/transcription domain-associated protein
K11304 TIP60, KAT5, ESA1; histone acetyltransferase HTATIP [EC:2.3.1.48]
K10151 CCND2; G1/S-specific cyclin-D2
K23068 p30II; HTLV-1 accessory protein p30II
K05718 ITGAL, CD11a; integrin alpha L
K06464 ITGB2, CD18; integrin beta 2
K06490 ICAM1, CD54; intercellular adhesion molecule 1
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K06454 CD4; T-cell surface glycoprotein CD4
K23017 gag; HTLV-1 gag polyprotein
K06271 TLN; talin
K23069 p12I; HTLV-1 accessory protein p12I
K23018 rex; HTLV-1 rex polyprotein
K15304 RANBP3; Ran-binding protein 3
K07936 RAN; GTP-binding nuclear protein Ran
K14290 XPO1, CRM1; exportin-1
K08057 CALR; calreticulin
K08054 CANX; calnexin
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K04446 NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
K17334 NFATC4, NFAT3; nuclear factor of activated T-cells, cytoplasmic 4
K05069 IL2RB, CD122; interleukin 2 receptor beta
K05070 IL2RG, CD132; interleukin 2 receptor gamma
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K05429 IL2; interleukin 2
K06751 MHC1; MHC class I antigen
K08055 B2M; beta-2-microglobulin
K00787 FDPS; farnesyl diphosphate synthase [EC:2.5.1.1 2.5.1.10]
K23070 p13; HTLV-1 accessory protein p13
K05862 VDAC1; voltage-dependent anion channel protein 1
K05863 SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K15040 VDAC2; voltage-dependent anion channel protein 2
K15041 VDAC3; voltage-dependent anion channel protein 3
K05770 TSPO, BZRP; translocator protein
K15305 VAC14, TAX1BP2; vacuole morphology and inheritance protein 14
K15306 RANBP1; Ran-binding protein 1
K21857 tax; HTLV protein Tax-1
K06679 MAD1; mitotic spindle assembly checkpoint protein MAD1
K02537 MAD2; mitotic spindle assembly checkpoint protein MAD2
K06637 BUB1B, BUBR1, MAD3L; mitotic checkpoint serine/threonine-protein kinase BUB1 beta [EC:2.7.11.1]
K02180 BUB3; cell cycle arrest protein BUB3
K03348 APC1; anaphase-promoting complex subunit 1
K03349 APC2; anaphase-promoting complex subunit 2
K03350 APC3, CDC27; anaphase-promoting complex subunit 3
K03351 APC4; anaphase-promoting complex subunit 4
K03352 APC5; anaphase-promoting complex subunit 5
K03353 APC6, CDC16; anaphase-promoting complex subunit 6
K03354 APC7; anaphase-promoting complex subunit 7
K03355 APC8, CDC23; anaphase-promoting complex subunit 8
K03357 APC10, DOC1; anaphase-promoting complex subunit 10
K03358 APC11; anaphase-promoting complex subunit 11
K03359 APC12, CDC26; anaphase-promoting complex subunit 12
K03363 CDC20; cell division cycle 20, cofactor of APC complex
K06635 PTTG; securin
K02365 ESP1; separase [EC:3.4.22.49]
K21770 CCNB2; G2/mitotic-specific cyclin-B2
K04685 CDKN2B, P15, INK4B; cyclin-dependent kinase inhibitor 2B
K06621 CDKN2A, P16, INK4A; cyclin-dependent kinase inhibitor 2A
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K04503 CCND1; G1/S-specific cyclin-D1
K10152 CCND3; G1/S-specific cyclin-D3
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K06627 CCNA; cyclin-A
K06626 CCNE; G1/S-specific cyclin-E1
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04728 ATM, TEL1; serine-protein kinase ATM [EC:2.7.11.1]
K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
K04451 TP53, P53; tumor protein p53
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K12076 DLG1; disks large protein 1
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K04416 MAP3K1, MEKK1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
K04430 MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K01397 MMP7; matrix metalloproteinase-7 (matrilysin, uterine) [EC:3.4.24.23]
K23071 HBZ; HTLV-1 basic zipper factor
K04386 IL1R1, CD121a; interleukin 1 receptor type I
K04387 IL1R2, CD121b; interleukin 1 receptor type II
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K06450 CD3D; T-cell surface glycoprotein CD3 delta chain
K06451 CD3E; T-cell surface glycoprotein CD3 epsilon chain
K06452 CD3G; T-cell surface glycoprotein CD3 gamma chain
K04421 MAP3K3, MEKK3; mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K15307 GPS2; G protein pathway suppressor 2
K03159 TNFRSF3, LTBR; lymphotoxin beta receptor TNFR superfamily member 3
K03160 TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
K05151 TNFRSF13C, BAFFR, CD268; tumor necrosis factor receptor superfamily member 13C
K04466 MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
K09253 RELB; transcription factor RelB
K04469 NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
K15308 TTP; tristetraprolin
K05068 IL2RA, CD25; interleukin 2 receptor alpha
K05433 IL15; interleukin 15
K05074 IL15RA, CD215; interleukin 15 receptor alpha
K05405 IL6; interleukin 6
K05427 CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
K05468 LTA, TNFB; lymphotoxin alpha (TNF superfamily, member 1)
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K04725 XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K08065 NFYB, HAP3; nuclear transcription Y subunit beta
K06752 MHC2; MHC class II antigen
K04378 SRF; serum response factor
K04376 ELK4, SAP1; ETS domain-containing protein Elk-4
K04375 ELK1; ETS domain-containing protein Elk-1
K09438 SPI1; transcription factor PU.1
K02678 ETS1, pnt; C-ets-1
K21932 ETS2; C-ets-2
K03120 TBP, tbp; transcription initiation factor TFIID TATA-box-binding protein
K04379 FOS; proto-oncogene protein c-fos
K09203 EGR1; early growth response protein 1
K04502 FOSL1; fos-like antigen 1
K12496 EGR2; early growth response protein 2
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
K15309 CRTC1, TORC1; CREB-regulated transcription coactivator 1
K16333 CRTC2, TORC2; CREB-regulated transcription coactivator 2
K16334 CRTC3, TORC3; CREB-regulated transcription coactivator 3
K04498 EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
K06062 PCAF, KAT2, GCN5; histone acetyltransferase [EC:2.3.1.48]
K09063 TCF3, E2A; transcription factor E2-alpha
K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
K05856 LCK; lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2]
K02159 BAX; apoptosis regulator BAX
K06622 CDKN2C, P18, INK4C; cyclin-dependent kinase inhibitor 2C
K11126 TERT, EST2; telomerase reverse transcriptase [EC:2.7.7.49]
K09341 MSX; homeobox protein MSX
K23454 gag-pro-pol; HTLV-1 gag-pro-pol polyprotein [EC:2.7.7.7 2.7.7.49 3.1.26.4]
|
05170 Human immunodeficiency virus 1 infection [PATH:ko05170]
|
05162 Measles [PATH:ko05162]
|
K19378 H; Morbillivirus hemagglutinin glycoprotein
K04007 CD46, MCP; membrane cofactor protein
K05763 MSN; moesin
K06536 SLAMF1, CD150; signaling lymphocytic activation molecule family member 1
K19379 F; Morbillivirus fusion glycoprotein F0
K06563 CLEC4M, DC-SIGN2, CD209, CD299; C-type lectin domain family 4 member M
K12646 DDX58, RIG-I; ATP-dependent RNA helicase DDX58 [EC:3.6.4.13]
K12647 IFIH1, MDA5; interferon-induced helicase C domain-containing protein 1 [EC:3.6.4.13]
K22281 V; measles non-structural protein V
K12648 MAVS, IPS1; mitochondrial antiviral-signaling protein
K03174 TRAF3; TNF receptor-associated factor 3
K07211 IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K05411 IRF3; interferon regulatory factor 3
K19380 N; Morbillivirus nucleoprotein
K22280 C; measles protein C
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K02581 NFKBIB; NF-kappa-B inhibitor beta
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K19377 P, P/V/C; Morbillivirus phosphoprotein
K05404 TLR7; toll-like receptor 7
K10161 TLR9, CD289; toll-like receptor 9
K04729 MYD88; myeloid differentiation primary response protein MyD88
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K09447 IRF7; interferon regulatory factor 7
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K10159 TLR2, CD282; toll-like receptor 2
K10160 TLR4, CD284; toll-like receptor 4
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K03097 CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
K03115 CSNK2B; casein kinase II subunit beta
K11859 TNFAIP3, A20, OTUD7C; tumor necrosis factor, alpha-induced protein 3 [EC:3.4.19.12]
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04404 MAP3K7IP2, TAB2; TAK1-binding protein 2
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04379 FOS; proto-oncogene protein c-fos
K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
K05405 IL6; interleukin 6
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K14753 RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K04693 IRF9, ISGF3G, P48; interferon regulatory factor 9
K14216 OAS; 2'-5'-oligoadenylate synthetase [EC:2.7.7.84]
K12968 ADAR, ADAR1; double-stranded RNA-specific adenosine deaminase [EC:3.5.4.37]
K14754 MX; interferon-induced GTP-binding protein Mx
K16194 EIF2AK1; eukaryotic translation initiation factor 2-alpha kinase 1 [EC:2.7.11.1]
K16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
K08860 EIF2AK3; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
K16196 EIF2AK4; eukaryotic translation initiation factor 2-alpha kinase 4 [EC:2.7.11.1]
K19381 M; Morbillivirus matrix protein
K19376 L; Paramyxoviridae RNA-directed RNA polymerase L
K07899 RAB9A, RAB9; Ras-related protein Rab-9A
K07900 RAB9B; Ras-related protein Rab-9B
K03283 HSPA1s; heat shock 70kDa protein 1/2/6/8
K03247 EIF3H; translation initiation factor 3 subunit H
K03237 EIF2S1; translation initiation factor 2 subunit 1
K10144 RCHY1, PIRH2; RING finger and CHY zinc finger domain-containing protein 1 [EC:2.3.2.27]
K04451 TP53, P53; tumor protein p53
K10148 TP73; tumor protein p73
K10132 BBC3, PUMA; Bcl-2-binding component 3
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K02159 BAX; apoptosis regulator BAX
K14021 BAK, BAK1; Bcl-2 homologous antagonist/killer
K02161 BCL2; apoptosis regulator Bcl-2
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K02158 BAD; Bcl-2-antagonist of cell death
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K06624 CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K06626 CCNE; G1/S-specific cyclin-E1
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K06450 CD3D; T-cell surface glycoprotein CD3 delta chain
K06451 CD3E; T-cell surface glycoprotein CD3 epsilon chain
K06452 CD3G; T-cell surface glycoprotein CD3 gamma chain
K06470 CD28; CD28 antigen
K05429 IL2; interleukin 2
K05068 IL2RA, CD25; interleukin 2 receptor alpha
K05069 IL2RB, CD122; interleukin 2 receptor beta
K05070 IL2RG, CD132; interleukin 2 receptor gamma
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K22517 CBLB; E3 ubiquitin-protein ligase CBL-B [EC:2.3.2.27]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K12560 FCGR2B, CD32; low affinity immunoglobulin gamma Fc receptor II-b
|
05164 Influenza A [PATH:ko05164]
|
05161 Hepatitis B [PATH:ko05161]
|
05160 Hepatitis C [PATH:ko05160]
|
05168 Herpes simplex virus 1 infection [PATH:ko05168]
|
05163 Human cytomegalovirus infection [PATH:ko05163]
|
05167 Kaposi sarcoma-associated herpesvirus infection [PATH:ko05167]
|
05169 Epstein-Barr virus infection [PATH:ko05169]
|
05165 Human papillomavirus infection [PATH:ko05165]
|
|
09174 Infectious disease: parasitic
|
05146 Amoebiasis [PATH:ko05146]
|
05144 Malaria [PATH:ko05144]
|
05145 Toxoplasmosis [PATH:ko05145]
|
05140 Leishmaniasis [PATH:ko05140]
|
05142 Chagas disease [PATH:ko05142]
|
K10160 TLR4, CD284; toll-like receptor 4
K05842 TRIF; toll-like receptor adapter molecule 1
K13729 TCAC2, TC52; thiol-dependent reductase 1
K10159 TLR2, CD282; toll-like receptor 2
K10169 TLR6, CD286; toll-like receptor 6
K10161 TLR9, CD289; toll-like receptor 9
K04729 MYD88; myeloid differentiation primary response protein MyD88
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K04430 MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04379 FOS; proto-oncogene protein c-fos
K04448 JUN; transcription factor AP-1
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K05415 IFNB; interferon beta
K12499 CCL5; C-C motif chemokine 5
K14624 CCL2, MCP1; C-C motif chemokine 2
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05405 IL6; interleukin 6
K10030 IL8, CXCL8; interleukin 8
K05408 CCL3; C-C motif chemokine 3
K04519 IL1B; interleukin 1 beta
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K04687 IFNG; interferon gamma
K05132 IFNGR1, CD119; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
K23590 CRP; complement regulatory protein
K03990 C3; complement component 3
K08057 CALR; calreticulin
K03986 C1QA; complement C1q subcomponent subunit A
K03987 C1QB; complement C1q subcomponent subunit B
K03988 C1QG; complement C1q subcomponent subunit C
K08571 E3.4.22.51; cruzipain [EC:3.4.22.51]
K05443 IL10, CSIF; interleukin 10
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K01283 ACE, CD143; peptidyl-dipeptidase A [EC:3.4.15.1]
K03898 KNG, BK; kininogen
K03916 BDKRB2; bradykinin receptor B2
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K04636 GNA14; guanine nucleotide-binding protein subunit alpha-14
K04637 GNA15; guanine nucleotide-binding protein subunit alpha-15
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K01354 ptrB; oligopeptidase B [EC:3.4.21.83]
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04534 GNAO, G-ALPHA-O; guanine nucleotide-binding protein G(o) subunit alpha
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K04633 GNAL; guanine nucleotide-binding protein G(olf) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K23591 TS; trans-sialidase [EC:3.2.1.-]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04674 TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K03982 SERPINE1, PAI1; plasminogen activator inhibitor 1
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04724 CFLAR, FLIP; CASP8 and FADD-like apoptosis regulator
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K06450 CD3D; T-cell surface glycoprotein CD3 delta chain
K06451 CD3E; T-cell surface glycoprotein CD3 epsilon chain
K06452 CD3G; T-cell surface glycoprotein CD3 gamma chain
K06453 CD3Z, CD247; CD3Z antigen, zeta polypeptide
K05429 IL2; interleukin 2
|
05143 African trypanosomiasis [PATH:ko05143]
|
|
09175 Drug resistance: antimicrobial
|
|
09176 Drug resistance: antineoplastic
|
|
09180 Brite Hierarchies
|
|
09181 Protein families: metabolism
|
|
09182 Protein families: genetic information processing
|
|
09183 Protein families: signaling and cellular processes
|
02000 Transporters [BR:ko02000]
|
02044 Secretion system [BR:ko02044]
|
02042 Bacterial toxins [BR:ko02042]
|
02022 Two-component system [BR:ko02022]
|
02035 Bacterial motility proteins [BR:ko02035]
|
04812 Cytoskeleton proteins [BR:ko04812]
|
04147 Exosome [BR:ko04147]
|
02048 Prokaryotic defense system [BR:ko02048]
|
04030 G protein-coupled receptors [BR:ko04030]
|
04050 Cytokine receptors [BR:ko04050]
|
04054 Pattern recognition receptors [BR:ko04054]
|
03310 Nuclear receptors [BR:ko03310]
|
04040 Ion channels [BR:ko04040]
|
04031 GTP-binding proteins [BR:ko04031]
|
04052 Cytokines and growth factors [BR:ko04052]
|
K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
K05481 IL1RN, IL1F3; interleukin 1 receptor antagonist
K05488 IL1F10, FKSG75; interleukin 1 family member 10
K05429 IL2; interleukin 2
K04736 IL3; interleukin 3
K05430 IL4; interleukin 4
K05428 IL5; interleukin 5
K05405 IL6; interleukin 6
K05431 IL7; interleukin 7
K05432 IL9; interleukin 9
K05443 IL10, CSIF; interleukin 10
K05417 IL11; interleukin 11
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05435 IL13; interleukin 13
K05433 IL15; interleukin 15
K22628 IL16; interleukin 16
K05489 IL17A, CTLA8; interleukin 17A
K05490 IL17B, CX1; interleukin 17B
K05491 IL17C, CX2; interleukin 17C
K05492 IL17D, IL27; interleukin 17D
K05493 IL17E, IL25; interleukin 17E
K05494 IL17F, ML1; interleukin 17F
K05482 IL18, IL1F4; interleukin 18
K05444 IL19; interleukin 19
K22667 IL20; interleukin 20
K05434 IL21; interleukin 21
K05445 IL22, IL-TIF; interleukin 22
K05426 IL23A; interleukin 23 subunit alpha
K22668 IL24; interleukin 24
K05446 IL26; interleukin 26
K22629 IL27, IL27A; interleukin-27 subunit alpha
K22631 IL31; interleukin 31
K22632 IL32; interleukin 32
K12967 IL33; interleukin 33
K22633 IL34; interleukin 34
K05484 IL36A, IL1F6; interleukin 36 alpha
K05486 IL36B, IL1F8; interleukin 36 beta
K05487 IL36G, IL1F9; interleukin 36 gamma
K05483 IL36RN, IL1F5; interleukin 36 receptor antagonist protein
K05485 IL37, IL1F7; interleukin 37
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K04687 IFNG; interferon gamma
K05442 IFNE; interferon epsilon
K05441 IFNK; interferon kappa
K05447 IFNL1, IL29; interferon lambda 1
K22669 IFNL2_3, IL28; interferon lambda 2/3
K05440 IFNW; interferon omega
K05453 CSF1, MCSF; macrophage colony-stimulating factor 1
K05427 CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
K05423 CSF3, GCSF; granulocyte colony-stimulating factor
K05437 EPO; erythropoietin
K05438 GH; growth hormone
K05439 PRL; prolactin
K06854 THPO; thrombopoietin
K05436 TSLP; thymic stromal lymphopoietin
K05418 OSM; oncostatin M
K05419 LIF; leukemia inhibitory factor
K05420 CNTF; ciliary neurotrophic factor
K05421 CLCF1, BSF3, CLC; cardiotrophin-like cytokine factor 1
K05422 CTF1, CT1; cardiotrophin 1
K24382 CTF2; cardiotrophin 2
K05424 LEP; leptin
K05514 CCL1; C-C motif chemokine 1
K14624 CCL2, MCP1; C-C motif chemokine 2
K05408 CCL3; C-C motif chemokine 3
K12964 CCL4; C-C motif chemokine 4
K12499 CCL5; C-C motif chemokine 5
K05510 CCL6; C-C motif chemokine 6
K05509 CCL7; C-C motif chemokine 7
K16596 CCL8; C-C motif chemokine 8
K22671 CCL9; C-C motif chemokine 9
K16597 CCL11; C-C motif chemokine 11
K16595 CCL13; C-C motif chemokine 13
K21092 CCL14; C-C motif chemokine 14
K05511 CCL15_23; C-C motif chemokine 15/23
K21093 CCL16; C-C motif chemokine 16
K21083 CCL17; C-C motif chemokine 17
K21094 CCL18; C-C motif chemokine 18
K05512 CCL19, ELC; C-C motif chemokine 19
K14625 CCL20; C-C motif chemokine 20
K16062 CCL21, SLC; C-C motif chemokine 21
K21095 CCL22; C-C motif chemokine 22
K21097 CCL24; C-C motif chemokine 24
K13072 CCL25; C-C motif chemokine 25
K21096 CCL26; C-C motif chemokine 26
K16598 CCL27; C-C motif chemokine 27
K05513 CCL28; C-C motif chemokine 28
K05505 CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
K05407 PF4, CXCL4; platelet factor 4
K05506 CXCL5_6, SCYB5_6; C-X-C motif chemokine 5/6
K10029 PPBP, CXCL7; platelet basic protein
K10030 IL8, CXCL8; interleukin 8
K05416 CXCL9; C-X-C motif chemokine 9
K12671 CXCL10, IP10; C-X-C motif chemokine 10
K12672 CXCL11, I-TAC; C-X-C motif chemokine 11
K10031 CXCL12; C-X-C motif chemokine 12
K10032 CXCL13; C-X-C motif chemokine 13
K10033 CXCL14, SCYB14; C-X-C motif chemokine 14
K10034 CXCL15; C-X-C motif chemokine 15
K10035 CXCL16; C-X-C motif chemokine 16
K22627 CXCL17; C-X-C motif chemokine 17
K05508 CX3CL1, NTT; C-X3-C motif chemokine 1
K05507 XCL1, SCM1; C motif chemokine 1
K22675 XCL2, SCM1B; C motif chemokine 2
K24191 PROK; prokineticin
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K05468 LTA, TNFB; lymphotoxin alpha (TNF superfamily, member 1)
K03157 LTB, TNFC; lymphotoxin beta (TNF superfamily, member 3)
K05469 TNFSF4, OX40L, CD252; tumor necrosis factor ligand superfamily member 4
K03161 TNFSF5, CD40L, CD154; tumor necrosis factor ligand superfamily member 5
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K05470 TNFSF7, CD70; tumor necrosis factor ligand superfamily member 7
K05471 TNFSF8, CD153; tumor necrosis factor ligand superfamily member 8
K05472 TNFSF9, CD137L; tumor necrosis factor ligand superfamily member 9
K04721 TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
K05473 TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
K05474 TNFSF12, TWEAK; tumor necrosis factor ligand superfamily member 12
K05475 TNFSF13, APRIL, CD256; tumor necrosis factor ligand superfamily member 13
K05476 TNFSF13B, TNFSF20, CD257; tumor necrosis factor ligand superfamily member 13B
K05477 TNFSF14, LIGHT, CD258; tumor necrosis factor ligand superfamily member 14
K05478 TNFSF15, VEGI; tumor necrosis factor ligand superfamily member 15
K05479 TNFSF18, GITRL; tumor necrosis factor ligand superfamily member 18
K05480 EDA; ectodysplasin-A
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04384 TGFBN; transforming growth factor beta, invertebrate
K05502 BMP1, TLD; bone morphogenetic protein 1 [EC:3.4.24.19]
K21283 BMP2; bone morphogenetic protein 2
K05496 BMP3; bone morphogenetic protein 3
K04662 BMP4; bone morphogenetic protein 4
K04663 BMP5; bone morphogenetic protein 5
K16620 BMP6; bone morphogenetic protein 6
K16621 BMP7; bone morphogenetic protein 7
K16622 BMP8; bone morphogenetic protein 8
K22670 BMP10; bone morphogenetic protein 10
K05498 BMP15, GDF9B; bone morphogenetic protein 15
K05495 GDF1; growth differentiation factor 1
K05503 GDF2, BMP9; growth differentiation factor 2
K22672 GDF3; growth differentiation factor 3
K04664 GDF5; growth differentiation factor 5
K20012 GDF6; growth differentiation factor 6
K20013 GDF7; growth differentiation factor 7
K05497 MSTN, GDF8; growth differentiation factor 8
K22673 GDF9; growth differentiation factor 9
K22674 GDF10, BMP3B; growth differentiation factor 10
K22679 GDF11; growth differentiation factor 11
K05504 GDF15; growth differentiation factor 15
K04666 NODAL; nodal
K05500 INHA; inhibin, alpha
K04667 INHBA; inhibin beta A chain
K22687 INHBB; inhibin beta B chain
K22688 INHBC; inhibin beta C chain
K22689 INHBE; inhibin beta E chain
K04665 AMH; anti-mullerian hormone
K04668 LEFTY; left-right determination factor
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K05450 PDGFC_D; platelet derived growth factor C/D
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K05449 VEGFC_D; vascular endothelial growth factor C/D
K16859 PGF; placenta growth factor
K05451 NGFA; nerve growth factor, alpha
K02582 NGFB; nerve growth factor, beta
K04356 NTF3; neurotrophin 3
K12457 NTF4; neurotrophin 4
K04355 BDNF; brain-derived neurotrophic factor
K05452 GDNF; glial cell derived neurotrophic factor
K05454 FLT3LG; fms-related tyrosine kinase 3 ligand
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K22413 FGF11_12_13, FHF3_1_2; fibroblast growth factor 11/12/13
K23920 FGF14, FHF4; fibroblast growth factor 14
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K05455 NRG1; neuregulin 1
K05456 NRG2; neuregulin 2
K05457 NRG3; neuregulin 3
K05458 NRG4; neuregulin 4
K05459 IGF1; insulin-like growth factor 1
K13769 IGF2; insulin-like growth factor 2
K05460 HGF; hepatocyte growth factor
K04357 EGF; epidermal growth factor
K05461 KITLG; KIT ligand
K05462 EFNA; ephrin-A
K05463 EFNB; ephrin-B
K05464 GAS6; growth arrest-specific 6
K05465 ANGPT1; angiopoietin 1
K05466 ANGPT2; angiopoietin 2
K05467 ANGPT4; angiopoietin 4
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04515 Cell adhesion molecules [BR:ko04515]
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04090 CD molecules [BR:ko04090]
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00535 Proteoglycans [BR:ko00535]
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00536 Glycosaminoglycan binding proteins [BR:ko00536]
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K04519 IL1B; interleukin 1 beta
K05429 IL2; interleukin 2
K04736 IL3; interleukin 3
K05430 IL4; interleukin 4
K05428 IL5; interleukin 5
K05431 IL7; interleukin 7
K05443 IL10, CSIF; interleukin 10
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05427 CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
K04687 IFNG; interferon gamma
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K14624 CCL2, MCP1; C-C motif chemokine 2
K05408 CCL3; C-C motif chemokine 3
K12499 CCL5; C-C motif chemokine 5
K16595 CCL13; C-C motif chemokine 13
K05407 PF4, CXCL4; platelet factor 4
K10030 IL8, CXCL8; interleukin 8
K12671 CXCL10, IP10; C-X-C motif chemokine 10
K10031 CXCL12; C-X-C motif chemokine 12
K06495 SELL, CD62L; selectin, lymphocyte
K06496 SELP, CD62P; selectin, platelet
K06461 ITGAM, CD11b; integrin alpha M
K06491 NCAM, CD56; neural cell adhesion molecule
K06471 PECAM1, CD31; platelet/endothelial cell adhesion molecule
K21283 BMP2; bone morphogenetic protein 2
K04662 BMP4; bone morphogenetic protein 4
K16621 BMP7; bone morphogenetic protein 7
K06224 HH; hedgehog
K11988 SHH; sonic hedgehog
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K09782 AREG; amphiregulin
K09783 BTC; betacellulin
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K22413 FGF11_12_13, FHF3_1_2; fibroblast growth factor 11/12/13
K23920 FGF14, FHF4; fibroblast growth factor 14
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K04362 FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2, CD332; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K08523 HBEGF; heparin-binding EGF-like growth factor
K05460 HGF; hepatocyte growth factor
K06828 MDK; midkine
K13769 IGF2; insulin-like growth factor 2
K05455 NRG1; neuregulin 1
K16641 HDGF; hepatoma-derived growth factor
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K16642 PTN; pleiotrophin
K05448 VEGFA; vascular endothelial growth factor A
K03903 FGA; fibrinogen alpha chain
K03904 FGB; fibrinogen beta chain
K03905 FGG; fibrinogen gamma chain
K05717 FN1; fibronectin 1
K06825 FBN1; fibrillin 1
K23342 FBN2_3; fibrillin 2/3
K06252 TN; tenascin
K24354 SMOC; SPARC-related modular calcium-binding protein
K16857 THBS1; thrombospondin 1
K04659 THBS2S; thrombospondin 2/3/4/5
K06251 VTN; vitronectin
K06236 COL1A; collagen type I alpha
K19719 COL2A; collagen type II alpha
K19720 COL3A; collagen type III alpha
K06237 COL4A; collagen type IV alpha
K19721 COL5AS; collagen type V/XI/XXIV/XXVII, alpha
K06238 COL6A; collagen type VI alpha
K16617 COL13A; collagen type XIII alpha
K06823 COL18A; collagen type XVIII alpha
K24340 COL19A; collagen type XIX alpha
K24355 COL23A; collagen type XXIII alpha
K24356 COL25A; collagen type XXV alpha
K05462 EFNA; ephrin-A
K06843 NTN1; netrin 1
K06838 SLIT1; slit 1
K06839 SLIT2; slit 2
K06850 SLIT3; slit 3
K01313 F2; coagulation factor II (thrombin) [EC:3.4.21.5]
K01314 F10; coagulation factor X [EC:3.4.21.6]
K03913 SERPINA5, PCI; protein C inhibitor
K03911 SERPINC1, AT3; antithrombin III
K03912 SERPIND1, HCF2; heparin cofactor II
K03982 SERPINE1, PAI1; plasminogen activator inhibitor 1
K16643 SERPINE2; glia-derived nexin
K01343 PLAT; tissue plasminogen activator [EC:3.4.21.68]
K01348 PLAU; urokinase plasminogen activator [EC:3.4.21.73]
K03909 TFPI; tissue factor pathway inhibitor
K01327 ELANE; leukocyte elastase [EC:3.4.21.37]
K07964 HPSE; heparanase [EC:3.2.1.166]
K07965 HPSE2; heparanase 2 [EC:3.2.1.-]
K01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35]
K01059 LPL; lipoprotein lipase [EC:3.1.1.34]
K16627 SOD3; superoxide dismutase, Cu-Zn family [EC:1.15.1.1]
K19252 VP1; Dependoparvovirus capsid protein VP1, adeno-associated virus type
K19255 gB; Herpesviridae envelope glycoprotein B
K19256 gC; Simplexvirus envelope glycoprotein C
K19264 gD; Simplexvirus envelope glycoprotein D
K19257 gM; Herpesviridae envelope glycoprotein M
K22773 gB, UL55; Betaherpesvirinae envelope glycoprotein B
K19287 gp160; HIV-1 envelope glycoprotein gp160
K19258 tat; HIV-1 protein Tat
K19259 env; HTLV envelope glycoprotein gp62
K19288 p130; Alphavirus structral polyprotein
K19260 L1; HPV major capsid protein L1
K19261 F; Orthopneumovirus fusion glycoprotein F0
K19262 L5; Mastadenovirus fiber protein
K19263 A27L; Orthopoxvirus protein A27
K13836 CSP; circumsporozoite protein
K15125 fhaB; filamentous hemagglutinin
K16644 actA; actin-assembly inducing protein
K16645 hbhA; heparin binding hemagglutinin HbhA
K16631 ANG, RNASE5; angiogenin [EC:3.1.27.-]
K16646 ANXA5; annexin A5
K09025 APOA5; apolipoprotein A-V
K14462 APOB; apolipoprotein B
K04524 APOE; apolipoprotein E
K04520 APP; amyloid beta A4 protein
K01363 CTSB; cathepsin B [EC:3.4.22.1]
K01319 CTSG; cathepsin G [EC:3.4.21.20]
K05634 PRNP, PrP, CD230; prion protein
K05849 SLC8A, NCX; solute carrier family 8 (sodium/calcium exchanger)
K01242 CD38; ADP-ribosyl cyclase 1 [EC:3.2.2.6 2.4.99.20]
K06256 CD44; CD44 antigen
K06267 HMMR, RHAMM, CD168; hyaluronan-mediated motility receptor
K06490 ICAM1, CD54; intercellular adhesion molecule 1
K10159 TLR2, CD282; toll-like receptor 2
K10160 TLR4, CD284; toll-like receptor 4
K10077 LAYN; layilin
K19012 LYVE1; lymphatic vessel endothelial hyaluronan receptor 1
K19020 STAB1; stabilin-1
K19013 STAB2, HARE; stabilin-2
K19031 CEMIP, KIAA1199; cell migration-inducing and hyaluronan-binding protein [EC:3.2.1.35]
K22144 TEME2; cell surface hyaluronidase [EC:3.2.1.35]
K06792 AGC1, CSPG1; aggrecan 1
K06795 BCAN; brevican
K15414 C1QBP; complement component 1 Q subcomponent-binding protein, mitochondrial
K08648 HABP2; hyaluronan binding protein 2 [EC:3.4.21.-]
K06848 HAPLN1, CRTL1; hyaluronan and proteoglycan link protein 1
K06851 HAPLN2; hyaluronan and proteoglycan link protein 2
K06853 HAPLN4; hyaluronan and proteoglycan link protein 4
K18977 HPX; hemopexin
K19014 ITIH1, SHAP; inter-alpha-trypsin inhibitor heavy chain H1
K19015 ITIH2, SHAP; inter-alpha-trypsin inhibitor heavy chain H2
K06794 NCAN, CSPG3; neurocan core protein
K19016 IMPG1, SPACR; interphotoreceptor matrix proteoglycan 1
K19017 IMPG2, SPACRCAN; interphotoreceptor matrix proteoglycan 2
K19018 TNFAIP6, TSG6; tumor necrosis factor-inducible gene 6 protein
K06793 VCAN, CSPG2; versican core protein
K09554 CDC37; cell division cycle protein 37
K19019 HABP4; intracellular hyaluronan-binding protein 4
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00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:ko00537]
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04091 Lectins [BR:ko04091]
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01504 Antimicrobial resistance genes [BR:ko01504]
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03200 Viral proteins [BR:ko03200]
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04990 Domain-containing proteins not elsewhere classified [BR:ko04990]
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09184 RNA family
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09190 Not Included in Pathway or Brite
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KEGG Orthology (KO)