KEGG ORTHOLOGY: K03175

KEGG Orthology (KO) [BR:ko00001]
09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    K03175  TRAF6; TNF receptor-associated factor 6
09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K03175  TRAF6; TNF receptor-associated factor 6
   04013 MAPK signaling pathway - fly
    K03175  TRAF6; TNF receptor-associated factor 6
   04064 NF-kappa B signaling pathway
    K03175  TRAF6; TNF receptor-associated factor 6
09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    K03175  TRAF6; TNF receptor-associated factor 6
   04140 Autophagy - animal
    K03175  TRAF6; TNF receptor-associated factor 6
  09143 Cell growth and death
   04214 Apoptosis - fly
    K03175  TRAF6; TNF receptor-associated factor 6
09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    K03175  TRAF6; TNF receptor-associated factor 6
   04621 NOD-like receptor signaling pathway
    K03175  TRAF6; TNF receptor-associated factor 6
   04622 RIG-I-like receptor signaling pathway
    K03175  TRAF6; TNF receptor-associated factor 6
   04657 IL-17 signaling pathway
    K03175  TRAF6; TNF receptor-associated factor 6
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    K03175  TRAF6; TNF receptor-associated factor 6
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K03175  TRAF6; TNF receptor-associated factor 6
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K03175  TRAF6; TNF receptor-associated factor 6
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    K03175  TRAF6; TNF receptor-associated factor 6
  09162 Cancer: specific types
   05222 Small cell lung cancer
    K03175  TRAF6; TNF receptor-associated factor 6
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    K03175  TRAF6; TNF receptor-associated factor 6
   05132 Salmonella infection
    K03175  TRAF6; TNF receptor-associated factor 6
   05131 Shigellosis
    K03175  TRAF6; TNF receptor-associated factor 6
   05135 Yersinia infection
    K03175  TRAF6; TNF receptor-associated factor 6
   05133 Pertussis
    K03175  TRAF6; TNF receptor-associated factor 6
   05152 Tuberculosis
    K03175  TRAF6; TNF receptor-associated factor 6
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K03175  TRAF6; TNF receptor-associated factor 6
   05161 Hepatitis B
    K03175  TRAF6; TNF receptor-associated factor 6
   05160 Hepatitis C
    K03175  TRAF6; TNF receptor-associated factor 6
   05171 Coronavirus disease - COVID-19
    K03175  TRAF6; TNF receptor-associated factor 6
   05162 Measles
    K03175  TRAF6; TNF receptor-associated factor 6
   05168 Herpes simplex virus 1 infection
    K03175  TRAF6; TNF receptor-associated factor 6
   05169 Epstein-Barr virus infection
    K03175  TRAF6; TNF receptor-associated factor 6
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    K03175  TRAF6; TNF receptor-associated factor 6
   05140 Leishmaniasis
    K03175  TRAF6; TNF receptor-associated factor 6
   05142 Chagas disease
    K03175  TRAF6; TNF receptor-associated factor 6
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K03175  TRAF6; TNF receptor-associated factor 6
   04121 Ubiquitin system
    K03175  TRAF6; TNF receptor-associated factor 6
Enzymes [BR:ko01000]
2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.27  RING-type E3 ubiquitin transferase
     K03175  TRAF6; TNF receptor-associated factor 6
Membrane trafficking [BR:ko04131]
Endocytosis
  Clathrin-mediated endocytosis
   Ubiquitin E3 ligases
    K03175  TRAF6; TNF receptor-associated factor 6
Ubiquitin system [BR:ko04121]
Ubiquitin ligases (E3)
  Single Ring-finger type E3
   TRAF proteins
    K03175  TRAF6; TNF receptor-associated factor 6

Genes

HSA:	7189(TRAF6)

PTR:	451702(TRAF6)

PPS:	100983960(TRAF6)

GGO:	101152087(TRAF6)

PON:	100449432(TRAF6)

NLE:	100595327(TRAF6)

MCC:	716907(TRAF6)

MCF:	102128596(TRAF6)

CSAB:

103237554(TRAF6)

RRO:	104658364(TRAF6)

RBB:	108535559(TRAF6)

CJC:	100395364(TRAF6)

SBQ:	101033308(TRAF6)

MMU:	22034(Traf6)

MCAL:

110290132(Traf6)

MPAH:

110318382(Traf6)

RNO:	311245(Traf6)

MUN:	110557497(Traf6)

CGE:	100753700(Traf6)

NGI:	103749513(Traf6)

HGL:	101697126(Traf6)

CCAN:

109693564(Traf6)

OCU:	100343190(TRAF6)

TUP:	102482652(TRAF6)

CFA:	100688110(TRAF6)

VVP:	112930471(TRAF6)

AML:	100483216(TRAF6)

UMR:	103659308(TRAF6)

UAH:	113265029(TRAF6)

ORO:	101362953(TRAF6)

ELK:

111150027

FCA:	101099750(TRAF6)

PTG:	102960157(TRAF6)

PPAD:

109279193(TRAF6)

AJU:	106976941(TRAF6)

BTA:	539124(TRAF6)

BOM:	102285891(TRAF6)

BIU:

109565970

BBUB:

102399580(TRAF6)

CHX:	102172830(TRAF6)

OAS:	101107132(TRAF6)

SSC:	396629(TRAF6)

CFR:	102520181(TRAF6)

CDK:	105106823(TRAF6)

BACU:

103018592(TRAF6)

LVE:

103088795

OOR:	101277553(TRAF6)

DLE:	111179772(TRAF6)

PCAD:

102993207(TRAF6)

ECB:	100052296(TRAF6)

EPZ:	103560236(TRAF6)

EAI:	106837480(TRAF6)

MYB:	102250946(TRAF6)

MYD:	102765934(TRAF6)

MNA:	107531990(TRAF6)

HAI:	109381153(TRAF6)

DRO:	112303407(TRAF6)

PALE:

102886476(TRAF6)

RAY:	107499247(TRAF6)

MJV:	108390300(TRAF6)

LAV:	100671471(TRAF6)

TMU:

101345331

MDO:	100010055(TRAF6)

SHR:	100922331(TRAF6)

PCW:	110192620(TRAF6)

OAA:	100077058(TRAF6)

GGA:	423163(TRAF6)

MGP:	100544809(TRAF6)

CJO:	107314700(TRAF6)

NMEL:

110401104(TRAF6)

APLA:

101802411(TRAF6)

ACYG:

106044346(TRAF6)

TGU:	100229606(TRAF6)

LSR:	110484454(TRAF6)

SCAN:

103826724(TRAF6)

GFR:	102040197(TRAF6)

FAB:	101817601(TRAF6)

PHI:	102105183(TRAF6)

PMAJ:

107206210(TRAF6)

CCAE:

111930105(TRAF6)

CCW:	104693976(TRAF6)

ETL:	114056738(TRAF6)

FPG:	101912003(TRAF6)

FCH:	102058044(TRAF6)

CLV:	102083770(TRAF6)

EGZ:	104134046(TRAF6)

NNI:

104019573

ACUN:

113481145(TRAF6)

PADL:

103921676(TRAF6)

AAM:	106498355(TRAF6)

ASN:	102368234(TRAF6)

AMJ:	102572036(TRAF6)

PSS:	102463398(TRAF6)

CMY:	102938959(TRAF6)

CPIC:

101953645(TRAF6)

ACS:	100561211(traf6)

PVT:	110090250(TRAF6)

PBI:	103052063(TRAF6)

PMUR:

107293338(TRAF6)

TSR:	106556967(TRAF6)

PMUA:

114600173(TRAF6)

GJA:	107116985(TRAF6)

XLA:	444777(traf6.L) 734929(traf6.S)

XTR:	493524(traf6)

NPR:	108787821(TRAF6)

DRE:	554561(traf6)

SRX:	107707871 107730254

SANH:

107694091 107696643

SGH:	107562521 107596425(traf6) 107596428

CCAR:

109065463 109093401(traf6)

IPU:	108259200(traf6)

PHYP:

113540966(traf6)

AMEX:

103021325(traf6)

EEE:	113579696(traf6)

TRU:	101071368(traf6)

TNG:	GSTEN00018197G001

LCO:	104920634(traf6)

NCC:	104948752(traf6)

MZE:	101469001(traf6)

ONL:	100703551(traf6)

OLA:	101161132(traf6)

XMA:	102220826(traf6)

XCO:	114142760(traf6)

PRET:

103462724(traf6)

CVG:	107099447(traf6)

NFU:	107383589(traf6)

KMR:	108234801(traf6)

ALIM:

106523547(traf6)

AOCE:

111571002(traf6)

CSEM:

103378810(traf6)

POV:	109637261(traf6)

LCF:	108887802(traf6)

SDU:	111223588(traf6)

SLAL:

111644323(traf6)

HCQ:	109525774(traf6)

BPEC:

110162549(traf6)

MALB:

109965061(traf6)

SASA:

106562692 106592035

OTW:

112247822

SALP:

112077783(traf6)

ELS:	105025313(traf6)

SFM:	108934700 108942315(traf6)

PKI:	111841418 111859511

LCM:	102353931(TRAF6)

CMK:	103186026(traf6)

RTP:	109936672(traf6)

BFO:

118414689

CIN:	778949(zf(traf/ring)-3)

SPU:	115925587 584052 585060

APLC:

110975424 110980832

SKO:	100372970 102804654

DME:	Dmel_CG10961(Traf6)

DER:

6550517

DSE:

6620179

DSI:	Dsimw501_GD16124(Dsim_GD16124)

DYA:	Dyak_GE17475

DSR:

110179707

DPO:	Dpse_GA10670

DPE:

6598159

DMN:

108164693

DWI:

6641099

DGR:	Dgri_GH24860

DMO:	Dmoj_GI14410

DAZ:

DNV:

DHE:

DVI:

MDE:

LCQ:

AGA:	AgaP_AGAP003004

AME:

BIM:

BTER:

CCAL:

OBB:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

LHU:

PGC:

OBO:

PCF:

MDL:

TCA:	661716(Traf2)

DPA:

ATD:

NVL:

BMOR:

BMAN:

DPL:	KGM_202662

PMAC:

PRAP:

HAW:

TNL:

PXY:	105382485 105389114

API:

DNX:

AGS:

RMD:

BTAB:

CLEC:

PHU:	Phum_PHUM129280

ZNE:

110826527

FCD:

110850863

PVM:

113823573

ISC:	IscW_ISCW011773 IscW_ISCW012083

CSCU:

111628924

HRO:	HELRODRAFT_194130

LGI:	LOTGIDRAFT_154170 LOTGIDRAFT_208992

PCAN:

112560472 112573637

CRG:	105346921 105348659

MYI:	110449364 110453157

OBI:

106878692

LAK:	106154806 106168821

NVE:

5520915

EPA:	110238205 110238648 110251240 110254378

ADF:	107330393 107332219 107345490 107354397 107355733 107355734 107355736 107355817 107355819

AMIL:

114953101 114953110 114953111 114953112 114953114 114953204 114953216 114957717

PDAM:

113665766 113665768 113679218 113685897

SPIS:

111329931 111329938 111330715 111334989 111339679 111344690 111345112 111345955

DGT:	114526503 114527425

TTT:	THITE_2123400

MGR:

MGG_03256

FGR:	FGSG_11967

FPU:	FPSE_00766

FVR:	FVEG_09651

FOX:	FOXG_11139

MAW:

MAC_05764

MAJ:

MAA_01724

CMT:

CCM_08969

PLJ:	VFPFJ_07301

DPP:	DICPUDRAFT_147424 DICPUDRAFT_18410 DICPUDRAFT_39824 DICPUDRAFT_39837 DICPUDRAFT_40987 DICPUDRAFT_44485 DICPUDRAFT_49369 DICPUDRAFT_7370 DICPUDRAFT_91159

» show all

Reference

PMID:19713527

Authors

Yang WL, Wang J, Chan CH, Lee SW, Campos AD, Lamothe B, Hur L, Grabiner BC, Lin X, Darnay BG, Lin HK

Title

The E3 ligase TRAF6 regulates Akt ubiquitination and activation.

Journal

Science 325:1134-8 (2009)
DOI:10.1126/science.1175065

Sequence

[hsa:7189]

Reference

PMID:8837778

Authors

Cao Z, Xiong J, Takeuchi M, Kurama T, Goeddel DV

Title

TRAF6 is a signal transducer for interleukin-1.

Journal

Nature 383:443-6 (1996)
DOI:10.1038/383443a0

Sequence

[hsa:7189]

LinkDB

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