 09100 Metabolism
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09120 Genetic Information Processing
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 09130 Environmental Information Processing
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09131 Membrane transport
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09132 Signal transduction
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02020 Two-component system [PATH:ko02020]
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04010 MAPK signaling pathway [PATH:ko04010]
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04013 MAPK signaling pathway - fly [PATH:ko04013]
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04016 MAPK signaling pathway - plant [PATH:ko04016]
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04011 MAPK signaling pathway - yeast [PATH:ko04011]
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04012 ErbB signaling pathway [PATH:ko04012]
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04014 Ras signaling pathway [PATH:ko04014]
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04015 Rap1 signaling pathway [PATH:ko04015]
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04310 Wnt signaling pathway [PATH:ko04310]
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04330 Notch signaling pathway [PATH:ko04330]
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04340 Hedgehog signaling pathway [PATH:ko04340]
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04341 Hedgehog signaling pathway - fly [PATH:ko04341]
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04350 TGF-beta signaling pathway [PATH:ko04350]
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04390 Hippo signaling pathway [PATH:ko04390]
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04391 Hippo signaling pathway - fly [PATH:ko04391]
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04392 Hippo signaling pathway - multiple species [PATH:ko04392]
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04370 VEGF signaling pathway [PATH:ko04370]
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04371 Apelin signaling pathway [PATH:ko04371]
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04630 JAK-STAT signaling pathway [PATH:ko04630]
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 K05429 IL2; interleukin 2
K05430 IL4; interleukin 4
K05431 IL7; interleukin 7
K05432 IL9; interleukin 9
K05433 IL15; interleukin 15
K05434 IL21; interleukin 21
K05436 TSLP; thymic stromal lymphopoietin
K05068 IL2RA, CD25; interleukin 2 receptor alpha
K05069 IL2RB, CD122; interleukin 2 receptor beta
K05070 IL2RG, CD132; interleukin 2 receptor gamma
K05071 IL4R, CD124; interleukin 4 receptor
K05072 IL7R, CD127; interleukin 7 receptor
K05073 IL9R, CD129; interleukin 9 receptor
K05074 IL15RA, CD215; interleukin 15 receptor alpha
K05075 IL21R, CD360; interleukin 21 receptor
K05078 TSLPR; thymic stromal-derived lymphopoietin receptor
K04736 IL3; interleukin 3
K05428 IL5; interleukin 5
K05427 CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
K04737 IL3RA, CD123; interleukin 3 receptor alpha
K05067 IL5RA, CD125; interleukin 5 receptor alpha
K05066 CSF2RA, GMCSFR, CD116; granulocyte-macrophage colony-stimulating factor receptor alpha
K04738 CSF2RB, IL3RB, CD131; cytokine receptor common subunit beta
K05405 IL6; interleukin 6
K05417 IL11; interleukin 11
K05435 IL13; interleukin 13
K22629 IL27, IL27A; interleukin 27 subunit alpha
K22631 IL31; interleukin 31
K05418 OSM; oncostatin M
K05419 LIF; leukemia inhibitory factor
K05420 CNTF; ciliary neurotrophic factor
K05422 CTF1, CT1; cardiotrophin 1
K24382 CTF2; cardiotrophin 2
K05421 CLCF1, BSF3, CLC; cardiotrophin-like cytokine factor 1
K05055 IL6R, CD126; interleukin 6 receptor
K05060 IL6ST, GP130, CD130; interleukin 6 signal transducer
K05056 IL11RA; interleukin 11 receptor alpha
K05076 IL13RA1, CD213A1; interleukin 13 receptor alpha-1
K05077 IL13RA2, CD213A2; interleukin 13 receptor alpha-2
K19598 IL27RA; interleukin 27 receptor alpha
K22630 IL31RA; interleukin 31 receptor subunit alpha
K05057 OSMR; oncostatin M receptor
K05058 LIFR, CD118; leukemia inhibitory factor receptor
K05059 CNTFR; ciliary neurotrophic factor receptor
K05443 IL10, CSIF; interleukin 10
K05444 IL19; interleukin 19
K05445 IL22, IL-TIF; interleukin 22
K22667 IL20; interleukin 20
K22668 IL24; interleukin 24
K05446 IL26; interleukin 26
K05134 IL10RA, CD210A; interleukin 10 receptor alpha
K05135 IL10RB, CD210B; interleukin 10 receptor beta
K05136 IL20RA; interleukin 20 receptor alpha
K05137 IL20RB; interleukin 20 receptor beta
K05138 IL22RA1; interleukin 22 receptor alpha 1
K05139 IL22RA2; interleukin 22 receptor alpha 2
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05426 IL23A; interleukin 23 subunit alpha
K05063 IL12RB1, CD212; interleukin 12 receptor beta-1
K05064 IL12RB2; interleukin 12 receptor beta-2
K05065 IL23R; interleukin 23 receptor
K05437 EPO; erythropoietin
K05438 GH; growth hormone
K05439 PRL; prolactin
K06854 THPO; thrombopoietin
K05423 CSF3, GCSF; granulocyte colony-stimulating factor
K05424 LEP; leptin
K16689 UPD; unpaired
K05079 EPOR; erythropoietin receptor
K05080 GHR; growth hormone receptor
K05081 PRLR; prolactin receptor
K05082 TPOR, MPL, CD110; thrombopoietin receptor
K05061 CSF3R, CD114; granulocyte colony-stimulating factor receptor
K05062 LEPR, CD295; leptin receptor
K19599 DOME; cytokine receptor domeless
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K05442 IFNE; interferon epsilon
K05441 IFNK; interferon kappa
K05447 IFNL1, IL29; interferon lambda 1
K22669 IFNL2_3, IL28; interferon lambda 2/3
K05440 IFNW; interferon omega
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K05140 IFNLR1, IL28RA; interferon lambda receptor 1
K04687 IFNG; interferon gamma
K05132 IFNGR1, CD119; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K04357 EGF; epidermal growth factor
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K04363 PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K04692 STAT3; signal transducer and activator of transcription 3
K11222 STAT4; signal transducer and activator of transcription 4
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K11225 STAT6; signal transducer and activator of transcription 6
K04693 IRF9, ISGF3G, P48; interferon regulatory factor 9
K04701 CISH; cytokine inducible SH2-containing protein
K04694 SOCS1, JAB; suppressor of cytokine signaling 1
K04695 SOCS2, CIS2; suppressor of cytokine signaling 2
K04696 SOCS3, CIS3; suppressor of cytokine signaling 3
K04697 SOCS4; suppressor of cytokine signaling 4
K04698 SOCS5; suppressor of cytokine signaling 5
K04699 SOCS6_7; suppressor of cytokine signaling 6/7
K02161 BCL2; apoptosis regulator Bcl-2
K02539 MCL1; myeloid leukemia cell differntiation protein MCL-1
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K04702 PIM1; proto-oncogene serine/threonine-protein kinase Pim-1 [EC:2.7.11.1]
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K00157 AOX; aldehyde oxidase [EC:1.2.3.1]
K05640 GFAP; glial fibrillary acidic protein
K04705 STAM; signal transducing adaptor molecule
K18026 PTPN2, PTPT; tyrosine-protein phosphatase non-receptor type 2 [EC:3.1.3.48]
K05697 PTPN6, SHP1; tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]
K04498 EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
K04706 PIAS1; E3 SUMO-protein ligase PIAS1 [EC:2.3.2.-]
K16063 PIAS2; E3 SUMO-protein ligase PIAS2 [EC:2.3.2.-]
K16064 PIAS3; E3 SUMO-protein ligase PIAS3 [EC:2.3.2.-]
K16065 PIAS4; E3 SUMO-protein ligase PIAS4 [EC:2.3.2.27]
K14365 FHL1, SLIM1; four and a half LIM domains protein 1
K07293 PTPN11, SHP2; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
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04064 NF-kappa B signaling pathway [PATH:ko04064]
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04668 TNF signaling pathway [PATH:ko04668]
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K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K09558 BAG4; BCL2-associated athanogene 4
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K09849 TRAF5; TNF receptor-associated factor 5
K02861 RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04403 MAP3K7IP1, TAB1; TAK1-binding protein 1
K04404 MAP3K7IP2, TAB2; TAK1-binding protein 2
K12793 MAP3K7IP3, TAB3; TAK1-binding protein 3
K04430 MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04379 FOS; proto-oncogene protein c-fos
K05632 ITCH, AIP4; E3 ubiquitin-protein ligase Itchy [EC:2.3.2.26]
K04724 CFLAR, FLIP; CASP8 and FADD-like apoptosis regulator
K04432 MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K10048 CEBPB; CCAAT/enhancer binding protein (C/EBP), beta
K04426 MAP3K5, ASK1; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04466 MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K04735 RELA; transcription factor p65
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04415 MAP3K8, COT; mitogen-activated protein kinase kinase kinase 8 [EC:2.7.11.25]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04445 RPS6KA5, MSK1; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
K16510 RPS6KA4, MSK2; ribosomal protein S6 kinase alpha-4 [EC:2.7.11.1]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
K08847 RIPK3; receptor-interacting serine/threonine-protein kinase 3 [EC:2.7.11.1]
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04400 CASP10; caspase 10 [EC:3.4.22.63]
K04397 CASP7; caspase 7 [EC:3.4.22.60]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K08849 MLKL; mixed lineage kinase domain-like [EC:2.7.11.1]
K15637 PGAM5; serine/threonine-protein phosphatase PGAM5 [EC:3.1.3.16]
K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
K08601 CYLD, USLP2; ubiquitin carboxyl-terminal hydrolase CYLD [EC:3.4.19.12]
K04725 XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K14624 CCL2, MCP1; C-C motif chemokine 2
K12499 CCL5; C-C motif chemokine 5
K14625 CCL20; C-C motif chemokine 20
K05505 CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
K05506 CXCL5_6, SCYB5_6; C-X-C motif chemokine 5/6
K12671 CXCL10, IP10; C-X-C motif chemokine 10
K05508 CX3CL1, NTT; C-X3-C motif chemokine 1
K05453 CSF1, MCSF; macrophage colony-stimulating factor 1
K05427 CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K05173 IL18R1, IL1RRP, CD218a; interleukin 18 receptor 1
K06052 JAG1, CD339; jagged-1
K04519 IL1B; interleukin 1 beta
K05405 IL6; interleukin 6
K05433 IL15; interleukin 15
K05419 LIF; leukemia inhibitory factor
K05468 LTA, TNFB; lymphotoxin alpha (TNF superfamily, member 1)
K09258 BCL3; B-cell CLL/lymphoma 3 protein
K04696 SOCS3, CIS3; suppressor of cytokine signaling 3
K11859 TNFAIP3, A20, OTUD7C; tumor necrosis factor, alpha-induced protein 3 [EC:3.4.19.12]
K03172 TRAF1; TNF receptor-associated factor 1
K17072 IFI47; interferon gamma inducible protein 47
K09028 JUNB; transcription factor jun-B
K01394 MMP3; matrix metalloproteinase-3 (stromelysin 1, progelatinase) [EC:3.4.24.17]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K07763 MMP14; matrix metalloproteinase-14 (membrane-inserted) [EC:3.4.24.80]
K16366 EDN1; endothelin-1
K05449 VEGFC_D; vascular endothelial growth factor C/D
K10165 NOD2, CARD15; nucleotide-binding oligomerization domain-containing protein 2
K06490 ICAM1, CD54; intercellular adhesion molecule 1
K06494 SELE, CD62E; selectin, endothelial cell
K06527 VCAM1, CD106; vascular cell adhesion molecule 1
K11987 PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K05141 TNFRSF1B, TNFR2, CD120b; tumor necrosis factor receptor superfamily member 1B
K03174 TRAF3; TNF receptor-associated factor 3
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K19901 DAB2IP, AIP1; disabled homolog 2-interacting protein
K09444 IRF1; interferon regulatory factor 1
K05415 IFNB; interferon beta
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04066 HIF-1 signaling pathway [PATH:ko04066]
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04068 FoxO signaling pathway [PATH:ko04068]
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04020 Calcium signaling pathway [PATH:ko04020]
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04070 Phosphatidylinositol signaling system [PATH:ko04070]
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04072 Phospholipase D signaling pathway [PATH:ko04072]
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04071 Sphingolipid signaling pathway [PATH:ko04071]
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04024 cAMP signaling pathway [PATH:ko04024]
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04022 cGMP-PKG signaling pathway [PATH:ko04022]
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04151 PI3K-Akt signaling pathway [PATH:ko04151]
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04152 AMPK signaling pathway [PATH:ko04152]
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04150 mTOR signaling pathway [PATH:ko04150]
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04075 Plant hormone signal transduction [PATH:ko04075]
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09133 Signaling molecules and interaction
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04080 Neuroactive ligand-receptor interaction [PATH:ko04080]
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04060 Cytokine-cytokine receptor interaction [PATH:ko04060]
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K05514 CCL1; C-C motif chemokine 1
K13072 CCL25; C-C motif chemokine 25
K05512 CCL19, ELC; C-C motif chemokine 19
K16062 CCL21, SLC; C-C motif chemokine 21
K05408 CCL3; C-C motif chemokine 3
K12964 CCL4; C-C motif chemokine 4
K21083 CCL17; C-C motif chemokine 17
K21095 CCL22; C-C motif chemokine 22
K12499 CCL5; C-C motif chemokine 5
K16596 CCL8; C-C motif chemokine 8
K22671 CCL9; C-C motif chemokine 9
K21092 CCL14; C-C motif chemokine 14
K21093 CCL16; C-C motif chemokine 16
K05511 CCL15_23; C-C motif chemokine 15/23
K16595 CCL13; C-C motif chemokine 13
K05510 CCL6; C-C motif chemokine 6
K05509 CCL7; C-C motif chemokine 7
K14624 CCL2, MCP1; C-C motif chemokine 2
K16597 CCL11; C-C motif chemokine 11
K21097 CCL24; C-C motif chemokine 24
K21096 CCL26; C-C motif chemokine 26
K16598 CCL27; C-C motif chemokine 27
K05513 CCL28; C-C motif chemokine 28
K21094 CCL18; C-C motif chemokine 18
K14625 CCL20; C-C motif chemokine 20
K05505 CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
K05506 CXCL5_6, SCYB5_6; C-X-C motif chemokine 5/6
K10030 IL8, CXCL8; interleukin 8
K10029 PPBP, CXCL7; platelet basic protein
K05407 PF4, CXCL4; platelet factor 4
K05416 CXCL9; C-X-C motif chemokine 9
K12671 CXCL10, IP10; C-X-C motif chemokine 10
K12672 CXCL11, I-TAC; C-X-C motif chemokine 11
K10032 CXCL13; C-X-C motif chemokine 13
K10031 CXCL12; C-X-C motif chemokine 12
K10035 CXCL16; C-X-C motif chemokine 16
K10033 CXCL14, SCYB14; C-X-C motif chemokine 14
K10034 CXCL15; C-X-C motif chemokine 15
K22627 CXCL17; C-X-C motif chemokine 17
K05507 XCL1, SCM1; C motif chemokine 1
K22675 XCL2, SCM1B; C motif chemokine 2
K05508 CX3CL1, NTT; C-X3-C motif chemokine 1
K05429 IL2; interleukin 2
K05430 IL4; interleukin 4
K05431 IL7; interleukin 7
K05432 IL9; interleukin 9
K05433 IL15; interleukin 15
K05434 IL21; interleukin 21
K05436 TSLP; thymic stromal lymphopoietin
K04736 IL3; interleukin 3
K05428 IL5; interleukin 5
K05427 CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
K05435 IL13; interleukin 13
K05437 EPO; erythropoietin
K05438 GH; growth hormone
K05439 PRL; prolactin
K06854 THPO; thrombopoietin
K05423 CSF3, GCSF; granulocyte colony-stimulating factor
K05424 LEP; leptin
K05405 IL6; interleukin 6
K05417 IL11; interleukin 11
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05426 IL23A; interleukin 23 subunit alpha
K22629 IL27, IL27A; interleukin 27 subunit alpha
K24476 EBI3, IL27B; interleukin 27 subunit beta
K22631 IL31; interleukin 31
K05421 CLCF1, BSF3, CLC; cardiotrophin-like cytokine factor 1
K05420 CNTF; ciliary neurotrophic factor
K05422 CTF1, CT1; cardiotrophin 1
K24382 CTF2; cardiotrophin 2
K05419 LIF; leukemia inhibitory factor
K05418 OSM; oncostatin M
K05443 IL10, CSIF; interleukin 10
K05444 IL19; interleukin 19
K22667 IL20; interleukin 20
K22668 IL24; interleukin 24
K05445 IL22, IL-TIF; interleukin 22
K05446 IL26; interleukin 26
K22669 IFNL2_3, IL28; interferon lambda 2/3
K05447 IFNL1, IL29; interferon lambda 1
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K05440 IFNW; interferon omega
K05441 IFNK; interferon kappa
K05442 IFNE; interferon epsilon
K04687 IFNG; interferon gamma
K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
K05481 IL1RN, IL1F3; interleukin 1 receptor antagonist
K05483 IL36RN, IL1F5; interleukin 36 receptor antagonist protein
K05484 IL36A, IL1F6; interleukin 36 alpha
K05486 IL36B, IL1F8; interleukin 36 beta
K05487 IL36G, IL1F9; interleukin 36 gamma
K05488 IL1F10, FKSG75; interleukin 1 family member 10
K05485 IL37, IL1F7; interleukin 37
K05482 IL18, IL1F4; interleukin 18
K12967 IL33; interleukin 33
K05489 IL17A, CTLA8; interleukin 17A
K05494 IL17F, ML1; interleukin 17F
K05490 IL17B, CX1; interleukin 17B
K05491 IL17C, CX2; interleukin 17C
K05492 IL17D, IL27; interleukin 17D
K05493 IL17E, IL25; interleukin 17E
K22628 IL16; interleukin 16
K22632 IL32; interleukin 32
K22633 IL34; interleukin 34
K05453 CSF1, MCSF; macrophage colony-stimulating factor 1
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K05468 LTA, TNFB; lymphotoxin alpha (TNF superfamily, member 1)
K03157 LTB, TNFC; lymphotoxin beta (TNF superfamily, member 3)
K05477 TNFSF14, LIGHT, CD258; tumor necrosis factor ligand superfamily member 14
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K05478 TNFSF15, VEGI; tumor necrosis factor ligand superfamily member 15
K04721 TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
K05480 EDA; ectodysplasin-A
K05451 NGFA; nerve growth factor, alpha
K02582 NGFB; nerve growth factor, beta
K05473 TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
K05474 TNFSF12, TWEAK; tumor necrosis factor ligand superfamily member 12
K05470 TNFSF7, CD70; tumor necrosis factor ligand superfamily member 7
K05471 TNFSF8, CD153; tumor necrosis factor ligand superfamily member 8
K03161 TNFSF5, CD40L, CD154; tumor necrosis factor ligand superfamily member 5
K05472 TNFSF9, CD137L; tumor necrosis factor ligand superfamily member 9
K05469 TNFSF4, OX40L, CD252; tumor necrosis factor ligand superfamily member 4
K05479 TNFSF18, GITRL; tumor necrosis factor ligand superfamily member 18
K05475 TNFSF13, APRIL, CD256; tumor necrosis factor ligand superfamily member 13
K05476 TNFSF13B, TNFSF20, CD257; tumor necrosis factor ligand superfamily member 13B
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K05504 GDF15; growth differentiation factor 15
K05503 GDF2, BMP9; growth differentiation factor 2
K22670 BMP10; bone morphogenetic protein 10
K05500 INHA; inhibin, alpha
K05496 BMP3; bone morphogenetic protein 3
K22674 GDF10, BMP3B; growth differentiation factor 10
K22679 GDF11; growth differentiation factor 11
K05497 MSTN, GDF8; growth differentiation factor 8
K04667 INHBA; inhibin beta A chain
K22687 INHBB; inhibin beta B chain
K05495 GDF1; growth differentiation factor 1
K22672 GDF3; growth differentiation factor 3
K04666 NODAL; nodal
K22673 GDF9; growth differentiation factor 9
K22688 INHBC; inhibin beta C chain
K22689 INHBE; inhibin beta E chain
K04665 AMH; anti-mullerian hormone
K21283 BMP2; bone morphogenetic protein 2
K04662 BMP4; bone morphogenetic protein 4
K04664 GDF5; growth differentiation factor 5
K20012 GDF6; growth differentiation factor 6
K20013 GDF7; growth differentiation factor 7
K05498 BMP15, GDF9B; bone morphogenetic protein 15
K04663 BMP5; bone morphogenetic protein 5
K16620 BMP6; bone morphogenetic protein 6
K16621 BMP7; bone morphogenetic protein 7
K16622 BMP8; bone morphogenetic protein 8
K04183 CCR8, CDw198; C-C chemokine receptor type 8
K04184 CCR9, CDw199; C-C chemokine receptor type 9
K04186 ACKR4, CCRL1, CCR11; atypical chemokine receptor 4
K04182 CCR7, CD197; C-C chemokine receptor type 7
K04179 CCR4, CD194; C-C chemokine receptor type 4
K04180 CCR5, CD195; C-C chemokine receptor type 5
K04178 CCR3, CD193; C-C chemokine receptor type 3
K04177 CCR2, CD192; C-C chemokine receptor type 2
K04176 CCR1, CD191; C-C chemokine receptor type 1
K04185 CCR10; C-C chemokine receptor type 10
K04181 CCR6, CD196; C-C chemokine receptor type 6
K04175 CXCR1, IL8RA, CD181; C-X-C chemokine receptor type 1
K05050 CXCR2, IL8RB, CD182; C-X-C chemokine receptor type 2
K04188 CXCR3, GPR9, CD183; C-X-C chemokine receptor type 3
K04190 CXCR5, BLR1, CD185; C-X-C chemokine receptor type 5
K04189 CXCR4, CD184; C-X-C chemokine receptor type 4
K04304 CXCR7, ACKR3, RDC1; C-X-C chemokine receptor type 7 (atypical chemokine receptor 3)
K04191 CXCR6, CD186; C-X-C chemokine receptor type 6
K04193 XCR1; XC chemokine receptor 1
K04192 CX3CR1; CX3C chemokine receptor 1
K05068 IL2RA, CD25; interleukin 2 receptor alpha
K05069 IL2RB, CD122; interleukin 2 receptor beta
K05070 IL2RG, CD132; interleukin 2 receptor gamma
K05071 IL4R, CD124; interleukin 4 receptor
K05072 IL7R, CD127; interleukin 7 receptor
K05073 IL9R, CD129; interleukin 9 receptor
K05074 IL15RA, CD215; interleukin 15 receptor alpha
K05075 IL21R, CD360; interleukin 21 receptor
K05078 TSLPR; thymic stromal-derived lymphopoietin receptor
K04737 IL3RA, CD123; interleukin 3 receptor alpha
K04738 CSF2RB, IL3RB, CD131; cytokine receptor common subunit beta
K05067 IL5RA, CD125; interleukin 5 receptor alpha
K05066 CSF2RA, GMCSFR, CD116; granulocyte-macrophage colony-stimulating factor receptor alpha
K05076 IL13RA1, CD213A1; interleukin 13 receptor alpha-1
K05077 IL13RA2, CD213A2; interleukin 13 receptor alpha-2
K05079 EPOR; erythropoietin receptor
K05080 GHR; growth hormone receptor
K05081 PRLR; prolactin receptor
K05082 TPOR, MPL, CD110; thrombopoietin receptor
K05061 CSF3R, CD114; granulocyte colony-stimulating factor receptor
K05062 LEPR, CD295; leptin receptor
K05055 IL6R, CD126; interleukin 6 receptor
K05060 IL6ST, GP130, CD130; interleukin 6 signal transducer
K05056 IL11RA; interleukin 11 receptor alpha
K05063 IL12RB1, CD212; interleukin 12 receptor beta-1
K05064 IL12RB2; interleukin 12 receptor beta-2
K05065 IL23R; interleukin 23 receptor
K19598 IL27RA; interleukin 27 receptor alpha
K22630 IL31RA; interleukin 31 receptor subunit alpha
K05059 CNTFR; ciliary neurotrophic factor receptor
K05058 LIFR, CD118; leukemia inhibitory factor receptor
K05057 OSMR; oncostatin M receptor
K05134 IL10RA, CD210A; interleukin 10 receptor alpha
K05135 IL10RB, CD210B; interleukin 10 receptor beta
K05136 IL20RA; interleukin 20 receptor alpha
K05137 IL20RB; interleukin 20 receptor beta
K05138 IL22RA1; interleukin 22 receptor alpha 1
K05140 IFNLR1, IL28RA; interferon lambda receptor 1
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K05132 IFNGR1, CD119; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K04386 IL1R1, CD121a; interleukin 1 receptor type I
K04723 IL1RAP; interleukin 1 receptor accessory protein
K04387 IL1R2, CD121b; interleukin 1 receptor type II
K05172 IL1RL2, IL1RRP2; interleukin 1 receptor-like 2
K05173 IL18R1, IL1RRP, CD218a; interleukin 18 receptor 1
K05174 IL18RAP, ACPL, CD218b; interleukin 18 receptor accessory protein
K05171 IL1RL1, ST2; interleukin 1 receptor-like 1
K05164 IL17RA, CD217; interleukin 17 receptor A
K05166 IL17RC, IL17RL; interleukin 17 receptor C
K05165 IL17RB, IL17RH1; interleukin 17 receptor B
K05168 IL17RE; interleukin 17 receptor E
K06454 CD4; T-cell surface glycoprotein CD4
K05090 CSF1R, FMS, CD115; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K05141 TNFRSF1B, TNFR2, CD120b; tumor necrosis factor receptor superfamily member 1B
K03159 TNFRSF3, LTBR; lymphotoxin beta receptor TNFR superfamily member 3
K05152 TNFRSF14, HVEM, CD270; tumor necrosis factor receptor superfamily member 14
K05143 TNFRSF6B, DCR3; tumor necrosis factor receptor superfamily member 6B
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K05160 TNFRSF25; tumor necrosis factor receptor superfamily member 25
K04722 TNFRSF10A_B, TRAILR1_2, DR4_5, CD261_2; tumor necrosis factor receptor superfamily member 10A/B
K22701 TNFRSF10C, TRAILR3, DCR1, CD263; tumor necrosis factor receptor superfamily member 10C
K22702 TNFRSF10D, TRAILR4, DCR2, CD264; tumor necrosis factor receptor superfamily member 10D
K05157 TNFRSF21, DR6, CD358; tumor necrosis factor receptor superfamily member 21
K05162 EDAR; tumor necrosis factor receptor superfamily member EDAR
K05163 EDA2R, TNFRSF27, XEDAR; tumor necrosis factor receptor superfamily member 27
K02583 NGFR, TNFRSF16, CD271; tumor necrosis factor receptor superfamily member 16
K05148 TNFRSF11B, OPG; tumor necrosis factor receptor superfamily member 11B
K05147 TNFRSF11A, RANK, CD265; tumor necrosis factor receptor superfamily member 11A
K05149 TNFRSF12A, FN14, TWEAKR, CD266; tumor necrosis factor receptor superfamily member 12A
K05144 TNFRSF7, CD27; tumor necrosis factor receptor superfamily member 7
K05145 TNFRSF8, CD30; tumor necrosis factor receptor superfamily member 8
K03160 TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
K05146 TNFRSF9, CD137; tumor necrosis factor receptor superfamily member 9
K05142 TNFRSF4, OX40, CD134; tumor necrosis factor receptor superfamily member 4
K05154 TNFRSF18, GITR, CD357; tumor necrosis factor receptor superfamily member 18
K05153 TNFRSF17, BCMA, CD269; tumor necrosis factor receptor superfamily member 17
K05150 TNFRSF13B, TACI, CD267; tumor necrosis factor receptor superfamily member 13B
K05151 TNFRSF13C, BAFFR, CD268; tumor necrosis factor receptor superfamily member 13C
K05155 TNFRSF19, TROY; tumor necrosis factor receptor superfamily member 19
K05156 RELT, TNFRSF19L; tumor necrosis factor receptor superfamily member 19-like
K26541 RELL; RELT-like protein
K04674 TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K13594 ACVRL1, ALK1; activin receptor-like kinase 1 [EC:2.7.11.30]
K04670 ACVR2A; activin receptor type-2A [EC:2.7.11.30]
K04671 BMPR2; bone morphogenetic protein receptor type-2 [EC:2.7.11.30]
K13596 ACVR2B; activin receptor type-2B [EC:2.7.11.30]
K13567 ACVR1B, ALK4; activin receptor type-1B [EC:2.7.11.30]
K13568 ACVR1C, ALK7; activin receptor type-1C [EC:2.7.11.30]
K04675 ACVR1, ALK2; activin receptor type-1 [EC:2.7.11.30]
K04672 AMHR2; anti-mullerian hormone receptor type-2 [EC:2.7.11.30]
K04673 BMPR1A, ALK3, CD292; bone morphogenetic protein receptor type-1A [EC:2.7.11.30]
K13578 BMPR1B, ALK6, CDw293; bone morphogenetic protein receptor type-1B [EC:2.7.11.30]
|
04061 Viral protein interaction with cytokine and cytokine receptor [PATH:ko04061]
|
04512 ECM-receptor interaction [PATH:ko04512]
|
04514 Cell adhesion molecules [PATH:ko04514]
|
|
09140 Cellular Processes
|
|
09150 Organismal Systems
|
|
09151 Immune system
|
04640 Hematopoietic cell lineage [PATH:ko04640]
|
K05461 KITLG; KIT ligand
K05431 IL7; interleukin 7
K05430 IL4; interleukin 4
K05427 CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
K05454 FLT3LG; fms-related tyrosine kinase 3 ligand
K05428 IL5; interleukin 5
K05423 CSF3, GCSF; granulocyte colony-stimulating factor
K04736 IL3; interleukin 3
K05405 IL6; interleukin 6
K05417 IL11; interleukin 11
K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K05453 CSF1, MCSF; macrophage colony-stimulating factor 1
K05437 EPO; erythropoietin
K06854 THPO; thrombopoietin
K06474 CD34; CD34 antigen
K05092 FLT3, FLK2, CD135; fms-related tyrosine kinase 3 [EC:2.7.10.1]
K00977 DNTT; DNA nucleotidylexotransferase [EC:2.7.7.31]
K06752 MHC2; MHC class II antigen
K06256 CD44; CD44 antigen
K05091 KIT, SCFR, CD117; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K05068 IL2RA, CD25; interleukin 2 receptor alpha
K05072 IL7R, CD127; interleukin 7 receptor
K06503 TFRC, CD71; transferrin receptor
K01242 CD38; ADP-ribosyl cyclase 1 [EC:3.2.2.6 2.4.99.20]
K06457 CD7; T-cell surface glycoprotein CD7
K06449 CD2; T-cell surface glycoprotein CD2
K06455 CD5; T-cell surface glycoprotein CD5
K06448 CD1; T-cell surface glycoprotein CD1
K06454 CD4; T-cell surface glycoprotein CD4
K06458 CD8A; T-cell surface glycoprotein CD8 alpha chain
K06459 CD8B; T-cell surface glycoprotein CD8 beta chain
K06450 CD3D; T-cell surface glycoprotein CD3 delta chain
K06451 CD3E; T-cell surface glycoprotein CD3 epsilon chain
K06452 CD3G; T-cell surface glycoprotein CD3 gamma chain
K01389 MME, CD10; neprilysin [EC:3.4.24.11]
K06460 CD9, TSPAN29; CD9 antigen
K06465 CD19; B-lymphocyte antigen CD19
K06467 CD22, SIGLEC2; CD22 antigen
K06469 CD24; CD24 antigen
K06466 MS4A1, CD20; B-lymphocyte antigen CD20
K04012 CR2, CD21; complement receptor type 2
K06475 CD37, TSPAN26; CD37 antigen
K06856 IGH; immunoglobulin heavy chain
K06468 FCER2, CD23; low affinity immunoglobulin epsilon Fc receptor
K04011 CR1, CD35; complement component (3b/4b) receptor 1
K05066 CSF2RA, GMCSFR, CD116; granulocyte-macrophage colony-stimulating factor receptor alpha
K04737 IL3RA, CD123; interleukin 3 receptor alpha
K06473 CD33, SIGLEC3; CD33 antigen
K05071 IL4R, CD124; interleukin 4 receptor
K05055 IL6R, CD126; interleukin 6 receptor
K06498 FCGR1A, CD64; high affinity immunoglobulin gamma Fc receptor I
K05090 CSF1R, FMS, CD115; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K11140 ANPEP, CD13; aminopeptidase N [EC:3.4.11.2]
K06461 ITGAM, CD11b; integrin alpha M
K04391 CD14; monocyte differentiation antigen CD14
K05073 IL9R, CD129; interleukin 9 receptor
K04386 IL1R1, CD121a; interleukin 1 receptor type I
K04387 IL1R2, CD121b; interleukin 1 receptor type II
K05061 CSF3R, CD114; granulocyte colony-stimulating factor receptor
K05067 IL5RA, CD125; interleukin 5 receptor alpha
K05079 EPOR; erythropoietin receptor
K06259 CD36; CD36 antigen
K06575 GYPA, CD235a; glycophorin A
K04006 DAF, CD55; decay accelerating factor
K04008 CD59; CD59 antigen
K05056 IL11RA; interleukin 11 receptor alpha
K06493 ITGB3, CD61; integrin beta 3
K06476 ITGA2B, CD41; integrin alpha 2B
K06263 GP9, CD42a; platelet glycoprotein IX
K06261 GP1BA, CD42b; platelet glycoprotein Ib alpha chain
K06262 GP1BB, CD42c; platelet glycoprotein Ib beta chain
K06260 GP5, CD42d; platelet glycoprotein V
K06480 ITGA1, CD49a; integrin alpha 1
K06481 ITGA2, CD49b; integrin alpha 2
K06482 ITGA3, CD49c; integrin alpha 3
K06483 ITGA4, CD49d; integrin alpha 4
K06484 ITGA5, CD49e; integrin alpha 5
K06485 ITGA6, CD49f; integrin alpha 6
|
04610 Complement and coagulation cascades [PATH:ko04610]
|
04611 Platelet activation [PATH:ko04611]
|
04613 Neutrophil extracellular trap formation [PATH:ko04613]
|
04620 Toll-like receptor signaling pathway [PATH:ko04620]
|
04624 Toll and Imd signaling pathway [PATH:ko04624]
|
04621 NOD-like receptor signaling pathway [PATH:ko04621]
|
04622 RIG-I-like receptor signaling pathway [PATH:ko04622]
|
04623 Cytosolic DNA-sensing pathway [PATH:ko04623]
|
04625 C-type lectin receptor signaling pathway [PATH:ko04625]
|
04650 Natural killer cell mediated cytotoxicity [PATH:ko04650]
|
K06751 MHC1; MHC class I antigen
K07980 KIR3DL, CD158; killer cell immunoglobulin-like receptor 3DL
K07981 KIR2DL1_2_3, CD158A_B; killer cell immunoglobulin-like receptor 2DL1/2/3
K24232 KIR2DL5, CD158F; killer cell immunoglobulin-like receptor 2DL5
K06541 KLRC1, NKG2A; killer cell lectin-like receptor subfamily C1
K06516 KLRD1, CD94; killer cell lectin-like receptor subfamily D member 1
K05697 PTPN6, SHP1; tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]
K07293 PTPN11, SHP2; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K06490 ICAM1, CD54; intercellular adhesion molecule 1
K06523 ICAM2, CD102; intercellular adhesion molecule 2
K05718 ITGAL, CD11a; integrin alpha L
K06464 ITGB2, CD18; integrin beta 2
K05871 PTK2B, FAK2; focal adhesion kinase 2 [EC:2.7.10.2]
K05730 VAV; guanine nucleotide exchange factor VAV
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K05427 CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
K04687 IFNG; interferon gamma
K07982 KIR2DS, CD158; killer cell immunoglobulin-like receptor 2DS
K24233 KLRC2_3, NKG2C_E; killer cell lectin-like receptor subfamily C2/3
K06742 NCR2, CD336; natural cytotoxicity triggering receptor 2
K07992 TYROBP, DAP12; TYRO protein tyrosine kinase binding protein
K05856 LCK; lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2]
K19251 HA; Influenza A virus hemagglutinin
K06856 IGH; immunoglobulin heavy chain
K06463 FCGR3, CD16; low affinity immunoglobulin gamma Fc receptor III
K06741 NCR1, CD335; natural cytotoxicity triggering receptor 1
K06743 NCR3, CD337; natural cytotoxicity triggering receptor 3
K07983 FCER1G; high affinity immunoglobulin epsilon receptor subunit gamma
K06453 CD3Z, CD247; CD3Z antigen, zeta polypeptide
K07360 ZAP70; tyrosine-protein kinase ZAP-70 [EC:2.7.10.2]
K05855 SYK; spleen tyrosine kinase [EC:2.7.10.2]
K07361 LCP2; lymphocyte cytosolic protein 2
K07362 LAT; linker for activation of T cells family member 1
K26356 LAT2, LAB; linker for activation of T-cells family member 2
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K07984 SH3BP2; SH3-domain binding protein 2
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K05703 FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K07985 MIC; MHC class I-related protein
K07986 ULBP; UL16 binding protein
K06728 KLRK1, CD314; killer cell lectin-like receptor subfamily K member 1
K07988 HCST, DAP10; hematopoietic cell signal transducer
K06479 CD48, BCM1; CD48 antigen
K06582 CD244; natural killer cell receptor 2B4
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K04446 NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K07989 SH2D1B, EAT2; SH2 domain-containing protein 1B
K07990 SH2D1A, SAP; SH2 domain-containing protein 1A
K05132 IFNGR1, CD119; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K04721 TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
K04722 TNFRSF10A_B, TRAILR1_2, DR4_5, CD261_2; tumor necrosis factor receptor superfamily member 10A/B
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K01353 GZMB; granzyme B [EC:3.4.21.79]
K07818 PRF1; perforin 1
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04726 BID; BH3 interacting domain death agonist
K24207 KLRA1, Ly49A; killer cell lectin-like receptor subfamily A member 1
K24208 KLRA3, Ly49C; killer cell lectin-like receptor subfamily A member 3
K24238 KLRA7, Ly49G2; killer cell lectin-like receptor subfamily A member 7
K24240 KLRA9, Ly49I; killer cell lectin-like receptor subfamily A member 9
K23459 KLRA4, LY49D; killer cell lectin-like receptor subfamily A member 4
K24239 KLRA8, Ly49H; killer cell lectin-like receptor subfamily A member 8
K07987 RAET1; retinoic acid early transcript 1
|
04612 Antigen processing and presentation [PATH:ko04612]
|
04660 T cell receptor signaling pathway [PATH:ko04660]
|
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K06450 CD3D; T-cell surface glycoprotein CD3 delta chain
K06451 CD3E; T-cell surface glycoprotein CD3 epsilon chain
K06452 CD3G; T-cell surface glycoprotein CD3 gamma chain
K06453 CD3Z, CD247; CD3Z antigen, zeta polypeptide
K06454 CD4; T-cell surface glycoprotein CD4
K06458 CD8A; T-cell surface glycoprotein CD8 alpha chain
K06459 CD8B; T-cell surface glycoprotein CD8 beta chain
K06478 PTPRC, CD45; receptor-type tyrosine-protein phosphatase C [EC:3.1.3.48]
K05856 LCK; lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2]
K05703 FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
K07360 ZAP70; tyrosine-protein kinase ZAP-70 [EC:2.7.10.2]
K07361 LCP2; lymphocyte cytosolic protein 2
K07362 LAT; linker for activation of T cells family member 1
K07363 ITK; IL2-inducible T-cell kinase [EC:2.7.10.2]
K07364 TEC; tyrosine-protein kinase Tec [EC:2.7.10.2]
K07365 NCK1; NCK adaptor protein 1
K19862 NCK2, GRB4; NCK adaptor protein 2
K05730 VAV; guanine nucleotide exchange factor VAV
K07366 GRAP2, GADS; GRB2-related adaptor protein 2
K04364 GRB2; growth factor receptor-bound protein 2
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04410 PAK2; p21-activated kinase 2 [EC:2.7.11.1]
K05733 PAK3, MRX30; p21-activated kinase 3 [EC:2.7.11.1]
K05734 PAK4; p21-activated kinase 4 [EC:2.7.11.1]
K05736 PAK5, PAK7; p21-activated kinase 5 [EC:2.7.11.1]
K05735 PAK6; p21-activated kinase 6 [EC:2.7.11.1]
K04513 RHOA; Ras homolog gene family, member A
K04393 CDC42; cell division control protein 42
K12076 DLG1; disks large protein 1
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K04446 NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
K03099 SOS; son of sevenless
K04350 RASGRP1; RAS guanyl-releasing protein 1
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04379 FOS; proto-oncogene protein c-fos
K04448 JUN; transcription factor AP-1
K18052 PRKCQ; novel protein kinase C theta type [EC:2.7.11.13]
K07367 CARD11; caspase recruitment domain-containing protein 11
K07368 BCL10; B-cell CLL/lymphoma 10
K07369 MALT1; mucosa-associated lymphoid tissue lymphoma translocation protein 1 [EC:3.4.22.-]
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02581 NFKBIB; NF-kappa-B inhibitor beta
K05872 NFKBIE; NF-kappa-B inhibitor epsilon
K06470 CD28; CD28 antigen
K06713 ICOS, AILIM, CD278; inducible T-cell co-stimulator
K03161 TNFSF5, CD40L, CD154; tumor necrosis factor ligand superfamily member 5
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04415 MAP3K8, COT; mitogen-activated protein kinase kinase kinase 8 [EC:2.7.11.25]
K04466 MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K06744 PDCD1, PD1, CD279; programmed cell death protein 1
K06538 CTLA4, CD152; cytotoxic T-lymphocyte-associated protein 4
K05697 PTPN6, SHP1; tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]
K07293 PTPN11, SHP2; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K22517 CBLB; E3 ubiquitin-protein ligase CBL-B [EC:2.3.2.27]
K05429 IL2; interleukin 2
K05430 IL4; interleukin 4
K05428 IL5; interleukin 5
K05443 IL10, CSIF; interleukin 10
K04687 IFNG; interferon gamma
K05427 CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
|
04658 Th1 and Th2 cell differentiation [PATH:ko04658]
|
04659 Th17 cell differentiation [PATH:ko04659]
|
04657 IL-17 signaling pathway [PATH:ko04657]
|
K05493 IL17E, IL25; interleukin 17E
K05164 IL17RA, CD217; interleukin 17 receptor A
K05165 IL17RB, IL17RH1; interleukin 17 receptor B
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K02373 FADD; FAS-associated death domain protein
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K21124 TRAF3IP2, ACT1; adaptor protein CIKS
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04379 FOS; proto-oncogene protein c-fos
K09029 FOSB; protein FosB
K04448 JUN; transcription factor AP-1
K04449 JUND; transcription factor jun-D
K04502 FOSL1; fos-like antigen 1
K05430 IL4; interleukin 4
K05428 IL5; interleukin 5
K05435 IL13; interleukin 13
K21083 CCL17; C-C motif chemokine 17
K16597 CCL11; C-C motif chemokine 11
K05489 IL17A, CTLA8; interleukin 17A
K05494 IL17F, ML1; interleukin 17F
K05166 IL17RC, IL17RL; interleukin 17 receptor C
K03174 TRAF3; TNF receptor-associated factor 3
K03352 APC5, ANAPC5; anaphase-promoting complex subunit 5
K11859 TNFAIP3, A20, OTUD7C; tumor necrosis factor, alpha-induced protein 3 [EC:3.4.19.12]
K04079 HSP90A, htpG; molecular chaperone HtpG
K09487 HSP90B, TRA1; heat shock protein 90kDa beta
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K04404 MAP3K7IP2, TAB2; TAK1-binding protein 2
K12793 MAP3K7IP3, TAB3; TAK1-binding protein 3
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K06855 MAPK4_6; mitogen-activated protein kinase 4/6 [EC:2.7.11.24]
K04464 MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
K19603 MAPK15; mitogen-activated protein kinase 15 [EC:2.7.11.24]
K10048 CEBPB; CCAAT/enhancer binding protein (C/EBP), beta
K09848 TRAF4; TNF receptor-associated factor 4
K07211 IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
K11849 USP25; ubiquitin carboxyl-terminal hydrolase 25 [EC:3.4.19.12]
K09849 TRAF5; TNF receptor-associated factor 5
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K12890 SRSF1, SFRS1, ASF, SF2; serine/arginine-rich splicing factor 1
K13088 ELAVL1, HUR; ELAV-like protein 1
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K05505 CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
K05506 CXCL5_6, SCYB5_6; C-X-C motif chemokine 5/6
K10030 IL8, CXCL8; interleukin 8
K12671 CXCL10, IP10; C-X-C motif chemokine 10
K14624 CCL2, MCP1; C-C motif chemokine 2
K05509 CCL7; C-C motif chemokine 7
K14625 CCL20; C-C motif chemokine 20
K05405 IL6; interleukin 6
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K11987 PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K05423 CSF3, GCSF; granulocyte colony-stimulating factor
K05427 CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
K21100 DEFB4; beta-defensin 4
K13908 MUC5; mucin-5
K21126 S100A7; protein S100-A7
K21127 S100A8; protein S100-A8
K21128 S100A9; protein S100-A9
K21129 LCN2; lipocalin 2
K01388 MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
K01394 MMP3; matrix metalloproteinase-3 (stromelysin 1, progelatinase) [EC:3.4.24.17]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K07994 MMP13; matrix metalloproteinase-13 (collagenase 3) [EC:3.4.24.-]
K05491 IL17C, CX2; interleukin 17C
K05168 IL17RE; interleukin 17 receptor E
K04519 IL1B; interleukin 1 beta
K04687 IFNG; interferon gamma
K05490 IL17B, CX1; interleukin 17B
K05492 IL17D, IL27; interleukin 17D
|
04662 B cell receptor signaling pathway [PATH:ko04662]
|
04664 Fc epsilon RI signaling pathway [PATH:ko04664]
|
K06856 IGH; immunoglobulin heavy chain
K08089 FCER1A; high affinity immunoglobulin epsilon receptor subunit alpha
K08090 MS4A2, FCER1B; high affinity immunoglobulin epsilon receptor subunit beta
K07983 FCER1G; high affinity immunoglobulin epsilon receptor subunit gamma
K05855 SYK; spleen tyrosine kinase [EC:2.7.10.2]
K05854 LYN; tyrosine-protein kinase Lyn [EC:2.7.10.2]
K07370 BTK; Bruton agammaglobulinemia tyrosine kinase [EC:2.7.10.2]
K03084 SHIP1, INPP5D; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 [EC:3.1.3.86]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04430 MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04432 MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K05430 IL4; interleukin 4
K05435 IL13; interleukin 13
K04736 IL3; interleukin 3
K05428 IL5; interleukin 5
K05427 CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K07361 LCP2; lymphocyte cytosolic protein 2
K05730 VAV; guanine nucleotide exchange factor VAV
K05703 FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
K08091 GAB2; GRB2-associated-binding protein 2
K07362 LAT; linker for activation of T cells family member 1
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K16342 PLA2G4, CPLA2; cytosolic phospholipase A2 [EC:3.1.1.4]
K00461 ALOX5; arachidonate 5-lipoxygenase [EC:1.13.11.34]
K20735 ALOX5AP, FLAP; arachidonate 5-lipoxygenase-activating protein
|
04666 Fc gamma R-mediated phagocytosis [PATH:ko04666]
|
04670 Leukocyte transendothelial migration [PATH:ko04670]
|
04672 Intestinal immune network for IgA production [PATH:ko04672]
|
04062 Chemokine signaling pathway [PATH:ko04062]
|
|
09152 Endocrine system
|
|
09153 Circulatory system
|
|
09154 Digestive system
|
|
09155 Excretory system
|
|
09156 Nervous system
|
|
09157 Sensory system
|
|
09158 Development and regeneration
|
|
09149 Aging
|
|
09159 Environmental adaptation
|
|
09160 Human Diseases
|
|
09161 Cancer: overview
|
05200 Pathways in cancer [PATH:ko05200]
|
05202 Transcriptional misregulation in cancer [PATH:ko05202]
|
K08367 RUNX1, AML1; runt-related transcription factor 1
K05090 CSF1R, FMS, CD115; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K10789 MPO; myeloperoxidase [EC:1.11.2.2]
K05427 CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
K04736 IL3; interleukin 3
K10053 RUNX1T1, CBFA2T1; CBFA2/RNUX1 translocation partner 1
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K11644 SIN3A; paired amphipathic helix protein Sin3a
K04650 NCOR1, N-CoR; nuclear receptor co-repressor 1
K09055 CEBPA; CCAAT/enhancer binding protein (C/EBP), alpha
K02633 PER2; period circadian protein 2
K09438 SPI1; transcription factor PU.1
K04391 CD14; monocyte differentiation antigen CD14
K06461 ITGAM, CD11b; integrin alpha M
K06498 FCGR1A, CD64; high affinity immunoglobulin gamma Fc receptor I
K10056 JUP, PG; junction plakoglobin
K10054 PML, TRIM19; E3 SUMO-protein ligase PML [EC:2.3.2.-]
K08527 RARA, NR1B1; retinoic acid receptor alpha
K06627 CCNA; cyclin-A
K10051 CEBPE; CCAAT/enhancer binding protein (C/EBP), epsilon
K02162 BCL2A1; hematopoietic Bcl-2-related protein A1
K10055 ZBTB16, PLZF; zinc finger and BTB domain-containing protein 16
K04377 MYC; Myc proto-oncogene protein
K21946 DUSP6; dual specificity phosphatase 6 [EC:3.1.3.16 3.1.3.48]
K09063 TCF3, E2A; transcription factor E2-alpha
K09355 PBX1; pre-B-cell leukemia transcription factor 1
K01558 WNT16; wingless-type MMTV integration site family, member 16
K03211 ETV6_7, yan; ETS translocation variant 6/7
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K05230 DEFA; defensin, alpha
K01327 ELANE; leukocyte elastase [EC:3.4.21.37]
K01353 GZMB; granzyme B [EC:3.4.21.79]
K09186 MLL1; [histone H3]-lysine4 N-trimethyltransferase MLL1 [EC:2.1.1.354]
K15184 AFF1; AF4/FMR2 family member 1
K02211 CDK9; cyclin-dependent kinase 9 [EC:2.7.11.22 2.7.11.23]
K15188 CCNT; cyclin T
K15187 MLLT1_3, ENL, AF9; YEATS domain-containing protein 1/3
K11427 DOT1L, DOT1; [histone H3]-lysine79 N-trimethyltransferase [EC:2.1.1.360]
K15612 LMO2; rhombotin-2
K15610 PBX3; pre-B-cell leukemia transcription factor 3
K09278 RUNX2, AML3; runt-related transcription factor 2
K04676 SMAD1; mothers against decapentaplegic homolog 1
K15605 KLF3; krueppel-like factor 3
K04454 MEF2C; MADS-box transcription enhancer factor 2C
K21950 HOXA9; homeobox protein Hox-A9
K17443 HOXA10; homrobox protein Hox-A10
K11449 JMJD1C; jumonji domain-containing protein 1C [EC:1.14.11.-]
K09283 HMGA2; high mobility group AT-hook protein 2
K11447 UTX, KDM6A; lysine-specific demethylase 6A [EC:1.14.11.68]
K11313 SUPT3H, SPT3; transcription initiation protein SPT3
K06532 PROM1, CD133; prominin 1
K05092 FLT3, FLK2, CD135; fms-related tyrosine kinase 3 [EC:2.7.10.1]
K08854 BMP2K, BIKE; BMP2 inducible kinase [EC:2.7.11.1]
K05087 IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K06624 CDKN1B, P27, KIP1; cyclin-dependent kinase inhibitor 1B
K08821 CDK14, PFTK1; cyclin-dependent kinase 14 [EC:2.7.11.22]
K15613 MEIS1; homeobox protein Meis1
K21951 HOXA11; homeobox protein Hox-A11
K15614 SIX1; homeobox protein SIX1
K15615 SIX4; homeobox protein SIX4
K15616 EYA1; eyes absent homolog 1 [EC:3.1.3.48]
K06622 CDKN2C, P18, INK4C; cyclin-dependent kinase inhibitor 2C
K00069 HPGD; 15-hydroxyprostaglandin dehydrogenase (NAD) [EC:1.1.1.141]
K05199 GRIA3; glutamate receptor 3
K00717 FUT8; glycoprotein 6-alpha-L-fucosyltransferase [EC:2.4.1.68]
K15607 TLX3, HOX11L2; T-cell leukemia homeobox protein 3
K09340 TLX1, HOX11; T-cell leukemia homeobox protein 1
K22046 BCL11B; B-cell lymphoma/leukemia 11B
K15617 LDB1; LIM domain-binding protein 1
K15604 LYL1; protein lyl-1
K08024 HHEX, HEX, PRH; homeobox protein HEX
K06056 PTCRA; pre T-cell antigen receptor alpha
K09254 REL; c-Rel proto-oncogene protein
K10151 CCND2; G1/S-specific cyclin-D2
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K03172 TRAF1; TNF receptor-associated factor 1
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K05413 CD86; CD86 antigen
K03160 TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
K15618 BCL6; B-cell lymphoma 6 protein
K06856 IGH; immunoglobulin heavy chain
K09035 CMAF, MAF; transcription factor Maf
K06590 ITGB7; integrin beta 7
K11424 WHSC1, MMSET, NSD2; [histone H3]-lysine36 N-dimethyltransferase NSD2 [EC:2.1.1.357]
K11253 H3; histone H3
K09383 PAX5; paired box protein 5
K09293 PAX8; paired box protein 8
K08530 NR1C3, PPARG; peroxisome proliferator-activated receptor gamma
K08524 RXRA, NR2B1; retinoid X receptor alpha
K08525 RXRB, NR2B2; retinoid X receptor beta
K08526 RXRG, NR2B3; retinoid X receptor gamma
K13105 PRCC; proline-rich protein PRCC
K09105 TFE3; transcription factor E3
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K09633 TMPRSS2; transmembrane protease serine 2 [EC:3.4.21.122]
K09435 ERG; transcriptional regulator ERG
K01348 PLAU; urokinase plasminogen activator [EC:3.4.21.73]
K01343 PLAT; tissue plasminogen activator [EC:3.4.21.68]
K01394 MMP3; matrix metalloproteinase-3 (stromelysin 1, progelatinase) [EC:3.4.24.17]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K09299 ZEB1; zinc finger homeobox protein 1
K04387 IL1R2, CD121b; interleukin 1 receptor type II
K15619 SPINT1; Kunitz-type protease inhibitor 1
K09431 ETV1; ets translocation variant 1
K15592 ETV4; ets translocation variant 4
K15593 ETV5; ets translocation variant 5
K15379 SLC45A3; solute carrier family 45, member 3
K04376 ELK4, SAP1; ETS domain-containing protein Elk-4
K12823 DDX5, DBP2; ATP-dependent RNA helicase DDX5/DBP2 [EC:5.6.2.7]
K09109 NMYC, MYCN; N-myc proto-oncogene protein
K04453 MAX; Max protein
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K04451 TP53, P53; tumor protein p53
K11459 PCGF4, BMI1; polycomb group RING finger protein 4
K04684 SP1; transcription factor Sp1
K10500 ZBTB17, MIZ1; zinc finger and BTB domain-containing protein 17
K03176 NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K02583 NGFR, TNFRSF16, CD271; tumor necrosis factor receptor superfamily member 16
K14970 MEN1, MNN1; menin
K13209 EWSR1; RNA-binding protein EWS
K09436 FLI1; friend leukemia integration 1 transcription factor
K05459 IGF1; insulin-like growth factor 1
K17693 ID2; DNA-binding protein inhibitor ID2
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K10138 IGFBP3; insulin-like growth factor-binding protein 3
K09437 FEV; ETS oncogene family protein FEV
K09053 ATF1; activating transcription factor 1
K15589 ARNT2; aryl hydrocarbon receptor nuclear translocator 2
K04728 ATM, TEL1; serine-protein kinase ATM [EC:2.7.11.1]
K09455 MITF; microphthalmia-associated transcription factor
K09234 WT1; Wilms tumor protein 1
K04359 PDGFA; platelet-derived growth factor subunit A
K05069 IL2RB, CD122; interleukin 2 receptor beta
K15621 BAIAP3; BAI1-associated protein 3
K06571 TSPAN7, TM4SF2, MXS1, CD231; tetraspanin-7
K15622 MLF1; myeloid leukemia factor 1
K08559 NR4A3, NOR1; nuclear receptor subfamily 4 group A member 3
K14651 TAF15, NPL3; transcription initiation factor TFIID subunit 15
K13098 TLS, FUS; RNA-binding protein FUS
K04452 DDIT3, GADD153; DNA damage-inducible transcript 3
K10048 CEBPB; CCAAT/enhancer binding protein (C/EBP), beta
K05405 IL6; interleukin 6
K14242 NFKBIZ; NF-kappa-B inhibitor zeta
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K10030 IL8, CXCL8; interleukin 8
K09381 PAX3_7; paired box protein 3/7
K07201 FOXO1; forkhead box protein O1
K05096 FLT1, VEGFR1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
K15623 SS18, SSXT, SYT, CREST; protein SSXT
K15624 SSX1; protein SSX1
K15625 SSX2; protein SSX2
K15626 NUPR1, COM1; nuclear protein 1
K15627 ASPSCR1, ASPL; tether containing UBX domain for GLUT4
K05099 MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK, BAK1; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
|
05206 MicroRNAs in cancer [PATH:ko05206]
|
05205 Proteoglycans in cancer [PATH:ko05205]
|
05204 Chemical carcinogenesis - DNA adducts [PATH:ko05204]
|
05207 Chemical carcinogenesis - receptor activation [PATH:ko05207]
|
05208 Chemical carcinogenesis - reactive oxygen species [PATH:ko05208]
|
05203 Viral carcinogenesis [PATH:ko05203]
|
05230 Central carbon metabolism in cancer [PATH:ko05230]
|
05231 Choline metabolism in cancer [PATH:ko05231]
|
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer [PATH:ko05235]
|
|
09162 Cancer: specific types
|
05210 Colorectal cancer [PATH:ko05210]
|
05212 Pancreatic cancer [PATH:ko05212]
|
05225 Hepatocellular carcinoma [PATH:ko05225]
|
05226 Gastric cancer [PATH:ko05226]
|
05214 Glioma [PATH:ko05214]
|
05216 Thyroid cancer [PATH:ko05216]
|
05221 Acute myeloid leukemia [PATH:ko05221]
|
K05091 KIT, SCFR, CD117; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K05092 FLT3, FLK2, CD135; fms-related tyrosine kinase 3 [EC:2.7.10.1]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K02158 BAD; Bcl-2-antagonist of cell death
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07828 NRAS; GTPase NRas
K07827 KRAS, KRAS2; GTPase KRas
K08845 ARAF, ARAF1; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04692 STAT3; signal transducer and activator of transcription 3
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K04702 PIM1; proto-oncogene serine/threonine-protein kinase Pim-1 [EC:2.7.11.1]
K08806 PIM2; proto-oncogene serine/threonine-protein kinase Pim-2 [EC:2.7.11.1]
K08367 RUNX1, AML1; runt-related transcription factor 1
K05090 CSF1R, FMS, CD115; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K10789 MPO; myeloperoxidase [EC:1.11.2.2]
K05427 CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
K04736 IL3; interleukin 3
K10053 RUNX1T1, CBFA2T1; CBFA2/RNUX1 translocation partner 1
K10054 PML, TRIM19; E3 SUMO-protein ligase PML [EC:2.3.2.-]
K08527 RARA, NR1B1; retinoic acid receptor alpha
K10055 ZBTB16, PLZF; zinc finger and BTB domain-containing protein 16
K09055 CEBPA; CCAAT/enhancer binding protein (C/EBP), alpha
K02633 PER2; period circadian protein 2
K09438 SPI1; transcription factor PU.1
K04391 CD14; monocyte differentiation antigen CD14
K06461 ITGAM, CD11b; integrin alpha M
K06498 FCGR1A, CD64; high affinity immunoglobulin gamma Fc receptor I
K10051 CEBPE; CCAAT/enhancer binding protein (C/EBP), epsilon
K02162 BCL2A1; hematopoietic Bcl-2-related protein A1
K06627 CCNA; cyclin-A
K04377 MYC; Myc proto-oncogene protein
K21946 DUSP6; dual specificity phosphatase 6 [EC:3.1.3.16 3.1.3.48]
K10056 JUP, PG; junction plakoglobin
K02620 TCF7, TCF-1; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K04503 CCND1; G1/S-specific cyclin-D1
K04504 NR1C2, PPARD; peroxisome proliferator-activated receptor delta
|
05220 Chronic myeloid leukemia [PATH:ko05220]
|
05217 Basal cell carcinoma [PATH:ko05217]
|
05218 Melanoma [PATH:ko05218]
|
05211 Renal cell carcinoma [PATH:ko05211]
|
05219 Bladder cancer [PATH:ko05219]
|
05215 Prostate cancer [PATH:ko05215]
|
05213 Endometrial cancer [PATH:ko05213]
|
05224 Breast cancer [PATH:ko05224]
|
05222 Small cell lung cancer [PATH:ko05222]
|
05223 Non-small cell lung cancer [PATH:ko05223]
|
|
09172 Infectious disease: viral
|
05166 Human T-cell leukemia virus 1 infection [PATH:ko05166]
|
K24862 gp46; HTLV envelope surface glycoprotein gp46
K24863 gp21; HTLV envelope transmembrane protein gp21
K07299 SLC2A1, GLUT1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
K06724 NRP1, CD304; neuropilin 1
K04377 MYC; Myc proto-oncogene protein
K08874 TRRAP; transformation/transcription domain-associated protein
K11304 TIP60, KAT5, ESA1; histone acetyltransferase HTATIP [EC:2.3.1.48]
K10151 CCND2; G1/S-specific cyclin-D2
K23068 p30II; HTLV-1 accessory protein p30II
K05718 ITGAL, CD11a; integrin alpha L
K06464 ITGB2, CD18; integrin beta 2
K06490 ICAM1, CD54; intercellular adhesion molecule 1
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K06454 CD4; T-cell surface glycoprotein CD4
K19259 env; Deltaretrovirus envelope glycoprotein gp62
K25051 MA; HTLV-1 matrix protein
K06271 TLN; talin
K23069 p12I; HTLV-1 accessory protein p12I
K23018 rex; HTLV-1 rex polyprotein
K15304 RANBP3; Ran-binding protein 3
K07936 RAN; GTP-binding nuclear protein Ran
K14290 XPO1, CRM1; exportin-1
K08057 CALR; calreticulin
K08054 CANX; calnexin
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K04446 NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
K17334 NFATC4, NFAT3; nuclear factor of activated T-cells, cytoplasmic 4
K05069 IL2RB, CD122; interleukin 2 receptor beta
K05070 IL2RG, CD132; interleukin 2 receptor gamma
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K05429 IL2; interleukin 2
K06751 MHC1; MHC class I antigen
K08055 B2M; beta-2-microglobulin
K00787 FDPS; farnesyl diphosphate synthase [EC:2.5.1.1 2.5.1.10]
K23070 p13; HTLV-1 accessory protein p13
K05862 VDAC1; voltage-dependent anion channel protein 1
K05863 SLC25A4S, ANT; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K15040 VDAC2; voltage-dependent anion channel protein 2
K15041 VDAC3; voltage-dependent anion channel protein 3
K05770 TSPO, BZRP; translocator protein
K15305 VAC14, TAX1BP2; vacuole morphology and inheritance protein 14
K15306 RANBP1; Ran-binding protein 1
K21857 tax; Deltaretrovirus protein Tax-1
K06679 MAD1; mitotic spindle assembly checkpoint protein MAD1
K02537 MAD2; mitotic spindle assembly checkpoint protein MAD2
K06637 BUB1B, BUBR1, MAD3L; mitotic checkpoint serine/threonine-protein kinase BUB1 beta [EC:2.7.11.1]
K02180 BUB3; cell cycle arrest protein BUB3
K03348 APC1, ANAPC1; anaphase-promoting complex subunit 1
K03349 APC2, ANAPC2; anaphase-promoting complex subunit 2
K03350 APC3, CDC27; anaphase-promoting complex subunit 3
K03351 APC4, ANAPC4; anaphase-promoting complex subunit 4
K03352 APC5, ANAPC5; anaphase-promoting complex subunit 5
K03353 APC6, CDC16; anaphase-promoting complex subunit 6
K03354 APC7, ANAPC7; anaphase-promoting complex subunit 7
K03355 APC8, CDC23; anaphase-promoting complex subunit 8
K03357 APC10, ANAPC10, DOC1; anaphase-promoting complex subunit 10
K03358 APC11, ANAPC11; anaphase-promoting complex subunit 11
K03359 APC12, CDC26; anaphase-promoting complex subunit 12
K12456 APC13, ANAPC13; anaphase-promoting complex subunit 13
K25228 APC15, ANAPC15; anaphase-promoting complex subunit 15
K25229 APC16, ANAPC16; anaphase-promoting complex subunit 16
K03363 CDC20; cell division cycle 20, cofactor of APC complex
K06635 PTTG; securin
K02365 ESP1; separase [EC:3.4.22.49]
K21770 CCNB2; G2/mitotic-specific cyclin-B2
K04685 CDKN2B, P15, INK4B; cyclin-dependent kinase inhibitor 2B
K06621 CDKN2A, P16, INK4A; cyclin-dependent kinase inhibitor 2A
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K04503 CCND1; G1/S-specific cyclin-D1
K10152 CCND3; G1/S-specific cyclin-D3
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K06627 CCNA; cyclin-A
K06626 CCNE; G1/S-specific cyclin-E1
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04728 ATM, TEL1; serine-protein kinase ATM [EC:2.7.11.1]
K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
K04451 TP53, P53; tumor protein p53
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K12076 DLG1; disks large protein 1
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K04416 MAP3K1, MEKK1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
K04430 MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K01397 MMP7; matrix metalloproteinase-7 (matrilysin, uterine) [EC:3.4.24.23]
K23071 HBZ; HTLV-1 basic zipper factor
K04386 IL1R1, CD121a; interleukin 1 receptor type I
K04387 IL1R2, CD121b; interleukin 1 receptor type II
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K06450 CD3D; T-cell surface glycoprotein CD3 delta chain
K06451 CD3E; T-cell surface glycoprotein CD3 epsilon chain
K06452 CD3G; T-cell surface glycoprotein CD3 gamma chain
K04421 MAP3K3, MEKK3; mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25]
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K15307 GPS2; G protein pathway suppressor 2
K03159 TNFRSF3, LTBR; lymphotoxin beta receptor TNFR superfamily member 3
K03160 TNFRSF5, CD40; tumor necrosis factor receptor superfamily member 5
K05151 TNFRSF13C, BAFFR, CD268; tumor necrosis factor receptor superfamily member 13C
K04466 MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]
K09253 RELB; transcription factor RelB
K04469 NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
K15308 TTP; tristetraprolin
K05068 IL2RA, CD25; interleukin 2 receptor alpha
K05433 IL15; interleukin 15
K05074 IL15RA, CD215; interleukin 15 receptor alpha
K05405 IL6; interleukin 6
K05427 CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
K05468 LTA, TNFB; lymphotoxin alpha (TNF superfamily, member 1)
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K04725 XIAP, BIRC4; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K08065 NFYB, HAP3; nuclear transcription Y subunit beta
K06752 MHC2; MHC class II antigen
K04378 SRF; serum response factor
K04376 ELK4, SAP1; ETS domain-containing protein Elk-4
K04375 ELK1; ETS domain-containing protein Elk-1
K09438 SPI1; transcription factor PU.1
K02678 ETS1, pnt; C-ets-1
K21932 ETS2; C-ets-2
K03120 TBP, tbp; transcription initiation factor TFIID TATA-box-binding protein
K04379 FOS; proto-oncogene protein c-fos
K09203 EGR1; early growth response protein 1
K04502 FOSL1; fos-like antigen 1
K12496 EGR2; early growth response protein 2
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K04450 ATF2, CREBP1; cyclic AMP-dependent transcription factor ATF-2
K04374 ATF4, CREB2; cyclic AMP-dependent transcription factor ATF-4
K09047 CREB5, CREBPA; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B, CREBL1; cyclic AMP-dependent transcription factor ATF-6 beta
K15309 CRTC1, TORC1; CREB-regulated transcription coactivator 1
K16333 CRTC2, TORC2; CREB-regulated transcription coactivator 2
K16334 CRTC3, TORC3; CREB-regulated transcription coactivator 3
K04498 EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
K06062 PCAF, KAT2, GCN5; histone acetyltransferase [EC:2.3.1.48]
K09063 TCF3, E2A; transcription factor E2-alpha
K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
K05856 LCK; lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2]
K02159 BAX; apoptosis regulator BAX
K06622 CDKN2C, P18, INK4C; cyclin-dependent kinase inhibitor 2C
K11126 TERT, EST2; telomerase reverse transcriptase [EC:2.7.7.49]
K09341 MSX; homeobox protein MSX
K25052 CA; HTLV-1 capsid protein
K25053 NC; HTLV-1 nucleocapsid protein
K25054 PR; HTLV-1 protease [EC:3.4.23.-]
K25055 RT; HTLV-1 reverse transcriptase / ribonuclease H [EC:2.7.7.49 2.7.7.7 3.1.26.4]
K25056 IN; HTLV-1 integrase
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05170 Human immunodeficiency virus 1 infection [PATH:ko05170]
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05161 Hepatitis B [PATH:ko05161]
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05160 Hepatitis C [PATH:ko05160]
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05171 Coronavirus disease - COVID-19 [PATH:ko05171]
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K25011 nsp1; SARS coronavirus host translation inhibitor nsp1
K25012 nsp2; SARS coronavirus non-structural protein 2
K25013 nsp3; SARS coronavirus non-structural protein 3 [EC:3.4.19.12]
K25014 nsp4; SARS coronavirus non-structural protein 4
K25015 nsp5; SARS coronavirus 3C-like proteinase [EC:3.4.22.69]
K25016 nsp6; SARS coronavirus non-structural protein 6
K25017 nsp7; SARS coronavirus non-structural protein 7
K25018 nsp8; SARS coronavirus non-structural protein 8
K25019 nsp9; SARS coronavirus non-structural protein 9
K25020 nsp10; SARS coronavirus non-structural protein 10
K25021 nsp12; Coronaviridae RNA-directed RNA polymerase [EC:2.7.7.48]
K25022 nsp13; SARS coronavirus helicase [EC:5.6.2.5]
K25023 nsp14; SARS coronavirus proofreading exoribonuclease [EC:3.1.13.-]
K25024 nsp15; SARS coronavirus uridylate-specific endoribonuclease
K25025 nsp16; SARS coronavirus 2'-O-methyltransferase [EC:2.1.1.-]
K24152 S; SARS coronavirus spike glycoprotein
K24151 E; SARS coronavirus envelope small membrane protein
K24150 M; SARS coronavirus membrane protein
K24106 N; SARS coronavirus nucleocapsid protein
K24579 3a; SARS coronavirus accessory protein 3a
K24580 6; SARS coronavirus accessory protein 6
K24581 7a; SARS coronavirus accessory protein 7a
K24582 7b; SARS coronavirus accessory protein 7b
K24583 8; SARS coronavirus accessory protein 8
K24584 10; SARS coronavirus accessory protein 10
K09633 TMPRSS2; transmembrane protease serine 2 [EC:3.4.21.122]
K09708 ACE2, ACEH; angiotensin-converting enzyme 2 [EC:3.4.17.23]
K06724 NRP1, CD304; neuropilin 1
K01283 ACE, CD143; peptidyl-dipeptidase A [EC:3.4.15.1]
K04303 MAS1; proto-oncogene Mas
K04166 AGTR1; angiotensin II receptor type 1
K21421 NOX2, GP91, CYBB; NADPH oxidase 2 [EC:1.-.-.-]
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K05405 IL6; interleukin 6
K04519 IL1B; interleukin 1 beta
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K01394 MMP3; matrix metalloproteinase-3 (stromelysin 1, progelatinase) [EC:3.4.24.17]
K01388 MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
K14624 CCL2, MCP1; C-C motif chemokine 2
K10030 IL8, CXCL8; interleukin 8
K06059 ADAM17, TACE, CD156b; disintegrin and metalloproteinase domain-containing protein 17 [EC:3.4.24.86]
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02581 NFKBIB; NF-kappa-B inhibitor beta
K08523 HBEGF; heparin-binding EGF-like growth factor
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K05055 IL6R, CD126; interleukin 6 receptor
K05060 IL6ST, GP130, CD130; interleukin 6 signal transducer
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K05429 IL2; interleukin 2
K05423 CSF3, GCSF; granulocyte colony-stimulating factor
K05427 CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
K12671 CXCL10, IP10; C-X-C motif chemokine 10
K02981 RP-S2e, RPS2; small subunit ribosomal protein S2e
K02985 RP-S3e, RPS3; small subunit ribosomal protein S3e
K02984 RP-S3Ae, RPS3A; small subunit ribosomal protein S3Ae
K02987 RP-S4e, RPS4; small subunit ribosomal protein S4e
K02989 RP-S5e, RPS5; small subunit ribosomal protein S5e
K02991 RP-S6e, RPS6; small subunit ribosomal protein S6e
K02993 RP-S7e, RPS7; small subunit ribosomal protein S7e
K02995 RP-S8e, RPS8; small subunit ribosomal protein S8e
K02997 RP-S9e, RPS9; small subunit ribosomal protein S9e
K02947 RP-S10e, RPS10; small subunit ribosomal protein S10e
K02949 RP-S11e, RPS11; small subunit ribosomal protein S11e
K02951 RP-S12e, RPS12; small subunit ribosomal protein S12e
K02953 RP-S13e, RPS13; small subunit ribosomal protein S13e
K02955 RP-S14e, RPS14; small subunit ribosomal protein S14e
K02958 RP-S15e, RPS15; small subunit ribosomal protein S15e
K02957 RP-S15Ae, RPS15A; small subunit ribosomal protein S15Ae
K02960 RP-S16e, RPS16; small subunit ribosomal protein S16e
K02962 RP-S17e, RPS17; small subunit ribosomal protein S17e
K02964 RP-S18e, RPS18; small subunit ribosomal protein S18e
K02966 RP-S19e, RPS19; small subunit ribosomal protein S19e
K02969 RP-S20e, RPS20; small subunit ribosomal protein S20e
K02971 RP-S21e, RPS21; small subunit ribosomal protein S21e
K02973 RP-S23e, RPS23; small subunit ribosomal protein S23e
K02974 RP-S24e, RPS24; small subunit ribosomal protein S24e
K02975 RP-S25e, RPS25; small subunit ribosomal protein S25e
K02976 RP-S26e, RPS26; small subunit ribosomal protein S26e
K02978 RP-S27e, RPS27; small subunit ribosomal protein S27e
K02977 RP-S27Ae, RPS27A, UBA80; ubiquitin-small subunit ribosomal protein S27Ae
K02979 RP-S28e, RPS28; small subunit ribosomal protein S28e
K02980 RP-S29e, RPS29; small subunit ribosomal protein S29e
K02983 RP-S30e, RPS30; small subunit ribosomal protein S30e
K02998 RP-SAe, RPSA; small subunit ribosomal protein SAe
K02925 RP-L3e, RPL3; large subunit ribosomal protein L3e
K02930 RP-L4e, RPL4; large subunit ribosomal protein L4e
K02932 RP-L5e, RPL5; large subunit ribosomal protein L5e
K02934 RP-L6e, RPL6; large subunit ribosomal protein L6e
K02937 RP-L7e, RPL7; large subunit ribosomal protein L7e
K02936 RP-L7Ae, RPL7A; large subunit ribosomal protein L7Ae
K02938 RP-L8e, RPL8; large subunit ribosomal protein L8e
K02940 RP-L9e, RPL9; large subunit ribosomal protein L9e
K02866 RP-L10e, RPL10; large subunit ribosomal protein L10e
K02865 RP-L10Ae, RPL10A; large subunit ribosomal protein L10Ae
K02868 RP-L11e, RPL11; large subunit ribosomal protein L11e
K02870 RP-L12e, RPL12; large subunit ribosomal protein L12e
K02873 RP-L13e, RPL13; large subunit ribosomal protein L13e
K02872 RP-L13Ae, RPL13A; large subunit ribosomal protein L13Ae
K02875 RP-L14e, RPL14; large subunit ribosomal protein L14e
K02877 RP-L15e, RPL15; large subunit ribosomal protein L15e
K02880 RP-L17e, RPL17; large subunit ribosomal protein L17e
K02883 RP-L18e, RPL18; large subunit ribosomal protein L18e
K02882 RP-L18Ae, RPL18A; large subunit ribosomal protein L18Ae
K02885 RP-L19e, RPL19; large subunit ribosomal protein L19e
K02889 RP-L21e, RPL21; large subunit ribosomal protein L21e
K02891 RP-L22e, RPL22; large subunit ribosomal protein L22e
K02894 RP-L23e, RPL23; large subunit ribosomal protein L23e
K02893 RP-L23Ae, RPL23A; large subunit ribosomal protein L23Ae
K02896 RP-L24e, RPL24; large subunit ribosomal protein L24e
K02898 RP-L26e, RPL26; large subunit ribosomal protein L26e
K02901 RP-L27e, RPL27; large subunit ribosomal protein L27e
K02900 RP-L27Ae, RPL27A; large subunit ribosomal protein L27Ae
K02903 RP-L28e, RPL28; large subunit ribosomal protein L28e
K02905 RP-L29e, RPL29; large subunit ribosomal protein L29e
K02908 RP-L30e, RPL30; large subunit ribosomal protein L30e
K02910 RP-L31e, RPL31; large subunit ribosomal protein L31e
K02912 RP-L32e, RPL32; large subunit ribosomal protein L32e
K02915 RP-L34e, RPL34; large subunit ribosomal protein L34e
K02918 RP-L35e, RPL35; large subunit ribosomal protein L35e
K02917 RP-L35Ae, RPL35A; large subunit ribosomal protein L35Ae
K02920 RP-L36e, RPL36; large subunit ribosomal protein L36e
K02922 RP-L37e, RPL37; large subunit ribosomal protein L37e
K02921 RP-L37Ae, RPL37A; large subunit ribosomal protein L37Ae
K02923 RP-L38e, RPL38; large subunit ribosomal protein L38e
K02924 RP-L39e, RPL39; large subunit ribosomal protein L39e
K02927 RP-L40e, RPL40, UBA52; ubiquitin-large subunit ribosomal protein L40e
K02928 RP-L41e, RPL41; large subunit ribosomal protein L41e
K02929 RP-L44e, RPL44; large subunit ribosomal protein L44e
K02941 RP-LP0, RPLP0; large subunit ribosomal protein LP0
K02942 RP-LP1, RPLP1; large subunit ribosomal protein LP1
K02943 RP-LP2, RPLP2; large subunit ribosomal protein LP2
K06856 IGH; immunoglobulin heavy chain
K06472 FCGR2A, CD32; low affinity immunoglobulin gamma Fc receptor II-a
K05855 SYK; spleen tyrosine kinase [EC:2.7.10.2]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K10159 TLR2, CD282; toll-like receptor 2
K10160 TLR4, CD284; toll-like receptor 4
K04729 MYD88; myeloid differentiation primary response protein MyD88
K05404 TLR7; toll-like receptor 7
K10170 TLR8, CD288; toll-like receptor 8
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04404 MAP3K7IP2, TAB2; TAK1-binding protein 2
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04379 FOS; proto-oncogene protein c-fos
K04448 JUN; transcription factor AP-1
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K12800 NLRP3, PYPAF1; NACHT, LRR and PYD domains-containing protein 3
K01370 CASP1; caspase 1 [EC:3.4.22.36]
K05401 TLR3, CD283; toll-like receptor 3
K12646 RIGI, DDX58; ATP-dependent RNA helicase DDX58 [EC:5.6.2.6]
K12159 ISG15; ubiquitin cross-reactive protein
K12647 IFIH1, MDA5; interferon-induced helicase C domain-containing protein 1 [EC:5.6.2.6]
K12648 MAVS, IPS1; mitochondrial antiviral-signaling protein
K03174 TRAF3; TNF receptor-associated factor 3
K07211 IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K05411 IRF3; interferon regulatory factor 3
K17834 CGAS, MB21D1; cyclic GMP-AMP synthase [EC:2.7.7.86]
K12654 STING1, TMEM173, MITA; stimulator of interferon genes protein
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K04693 IRF9, ISGF3G, P48; interferon regulatory factor 9
K12968 ADAR, ADAR1; double-stranded RNA-specific adenosine deaminase [EC:3.5.4.37]
K14216 OAS; 2'-5'-oligoadenylate synthetase [EC:2.7.7.84]
K14754 MX; interferon-induced GTP-binding protein Mx
K16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
K04010 C5AR1, CD88; C5a anaphylatoxin chemotactic receptor 1
K04009 C3AR1; C3a anaphylatoxin chemotactic receptor
K03990 C3; complement component 3
K01335 CFB; complement factor B [EC:3.4.21.47]
K01334 CFD; complement factor D [EC:3.4.21.46]
K03994 C5; complement component 5
K03995 C6; complement component 6
K03996 C7; complement component 7
K03997 C8A; complement component 8 subunit alpha
K03998 C8B; complement component 8 subunit beta
K03999 C8G; complement component 8 subunit gamma
K04000 C9; complement component 9
K06496 SELP, CD62P; selectin, platelet
K03900 VWF; von Willebrand factor
K03986 C1QA; complement C1q subcomponent subunit A
K03987 C1QB; complement C1q subcomponent subunit B
K03988 C1QG; complement C1q subcomponent subunit C
K01330 C1R; complement component 1, r subcomponent [EC:3.4.21.41]
K01331 C1S; complement component 1, s subcomponent [EC:3.4.21.42]
K01332 C2; complement component 2 [EC:3.4.21.43]
K03989 C4; complement component 4
K03991 MBL; mannose-binding lectin
K03992 MASP1; mannan-binding lectin serine protease 1 [EC:3.4.21.-]
K03993 MASP2; mannan-binding lectin serine protease 2 [EC:3.4.21.104]
K01313 F2; coagulation factor II (thrombin) [EC:3.4.21.5]
K03917 F13A1; coagulation factor XIII A1 polypeptide [EC:2.3.2.13]
K03906 F13B; coagulation factor XIII B polypeptide
K03903 FGA; fibrinogen alpha chain
K03904 FGB; fibrinogen beta chain
K03905 FGG; fibrinogen gamma chain
|
05164 Influenza A [PATH:ko05164]
|
05162 Measles [PATH:ko05162]
|
05168 Herpes simplex virus 1 infection [PATH:ko05168]
|
05163 Human cytomegalovirus infection [PATH:ko05163]
|
05167 Kaposi sarcoma-associated herpesvirus infection [PATH:ko05167]
|
K21649 ORF4; KSHV complement control protein
K03990 C3; complement component 3
K05401 TLR3, CD283; toll-like receptor 3
K05842 TRIF; toll-like receptor adapter molecule 1
K03174 TRAF3; TNF receptor-associated factor 3
K07211 IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K09447 IRF7; interferon regulatory factor 7
K21650 KIE1, ORF50; KSHV transcription activator ORF50
K21859 KIE2, ORF45; KSHV transcription activator ORF45
K21652 vIRF3; KSHV interferon regulatory factor-like protein 3
K05414 IFNA; interferon alpha
K05411 IRF3; interferon regulatory factor 3
K21653 vIRF1, K9; KSHV interferon regulatory factor-like protein 1
K21654 vIRF2, K11; KSHV interferon regulatory factor-like protein 2
K21655 K8; KSHV E3 SUMO-protein ligase K-bZIP
K04498 EP300, CREBBP, KAT3; E1A/CREB-binding protein [EC:2.3.1.48]
K05415 IFNB; interferon beta
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K04693 IRF9, ISGF3G, P48; interferon regulatory factor 9
K16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
K21656 K12; KSHV protein K12
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04443 MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
K04433 MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K15308 TTP; tristetraprolin
K05405 IL6; interleukin 6
K05427 CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
K21657 K4; KSHV macrophage inflammatory protein 2
K04178 CCR3, CD193; C-C chemokine receptor type 3
K04180 CCR5, CD195; C-C chemokine receptor type 5
K04176 CCR1, CD191; C-C chemokine receptor type 1
K21658 K4.1; KSHV protein vCCL3
K04179 CCR4, CD194; C-C chemokine receptor type 4
K21659 K6; KSHV protein K6
K04183 CCR8, CDw198; C-C chemokine receptor type 8
K04390 TNFRSF6, FAS, CD95; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K21660 vBCL2, ORF16; KSHV apoptosis regulator BCL2 homolog
K02159 BAX; apoptosis regulator BAX
K14021 BAK, BAK1; Bcl-2 homologous antagonist/killer
K08738 CYC; cytochrome c
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K21661 vIAP, K7; KSHV inhibitor of apoptosis protein
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K21662 vFLIP, K13, ORF71; KSHV FLICE inhibitory protein
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K21651 K15; KSHV signal transducing membrane protein
K04451 TP53, P53; tumor protein p53
K06625 CDKN1A, P21, CIP1; cyclin-dependent kinase inhibitor 1A
K21663 vCyclin, ORF72; KSHV cyclin homolog
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K21664 vLANA, ORF73; KSHV latency-associated nuclear antigen
K06751 MHC1; MHC class I antigen
K21665 MIR1, K3; KSHV E3 ubiquitin-protein ligase MIR1 [EC:2.3.2.36]
K21666 MIR2, K5; KSHV E3 ubiquitin-protein ligase MIR2 [EC:2.3.2.36]
K05132 IFNGR1, CD119; interferon gamma receptor 1
K06490 ICAM1, CD54; intercellular adhesion molecule 1
K05413 CD86; CD86 antigen
K07985 MIC; MHC class I-related protein
K10071 CLEC2B; C-type lectin domain family 2 member B
K02927 RP-L40e, RPL40, UBA52; ubiquitin-large subunit ribosomal protein L40e
K02977 RP-S27Ae, RPS27A, UBA80; ubiquitin-small subunit ribosomal protein S27Ae
K04551 UBB; ubiquitin B
K08770 UBC; ubiquitin C
K08334 BECN, VPS30, ATG6; beclin
K17889 ATG14L, ATG14; beclin 1-associated autophagy-related key regulator
K00914 PIK3C3, VPS34; phosphatidylinositol 3-kinase [EC:2.7.1.137]
K08343 ATG3; ubiquitin-like-conjugating enzyme ATG3
K10435 MAP1LC; microtubule-associated protein 1 light chain
K21667 vGPCR; KSHV G-protein coupled receptor
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K02833 HRAS; GTPase HRas
K07827 KRAS, KRAS2; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K04448 JUN; transcription factor AP-1
K04379 FOS; proto-oncogene protein c-fos
K21289 PIK3CG; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma [EC:2.7.1.153]
K21290 PIK3R5_6; phosphoinositide-3-kinase regulatory subunit 5/6
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K12365 PREX1; phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchanger 1 protein
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K21860 K14; KSHV OX-2 membrane glycoprotein
K21668 CD200R; cell surface glycoprotein CD200 receptor
K21669 K1; KSHV protein K1
K05855 SYK; spleen tyrosine kinase [EC:2.7.10.2]
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K08893 HCK; hemopoietic cell kinase [EC:2.7.10.2]
K05854 LYN; tyrosine-protein kinase Lyn [EC:2.7.10.2]
K04430 MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K02183 CALM; calmodulin
K04348 PPP3C, CNA; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R, CNB; serine/threonine-protein phosphatase 2B regulatory subunit
K04446 NFATC1, NFAT2, NFATC; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2, NFAT1, NFATP; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3, NFAT4; nuclear factor of activated T-cells, cytoplasmic 3
K17334 NFATC4, NFAT3; nuclear factor of activated T-cells, cytoplasmic 4
K10030 IL8, CXCL8; interleukin 8
K11987 PTGS2, COX2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K05505 CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
K17901 RCAN1, MCIP1; calcipressin-1
K18497 FGF2; fibroblast growth factor 2
K05448 VEGFA; vascular endothelial growth factor A
K17386 PDGFB; platelet-derived growth factor subunit B
K21670 vIL6, K2; KSHV interleukin 6
K05466 ANGPT2; angiopoietin 2
K05060 IL6ST, GP130, CD130; interleukin 6 signal transducer
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02105 CTNNB1; catenin beta 1
K02620 TCF7, TCF-1; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04503 CCND1; G1/S-specific cyclin-D1
K04377 MYC; Myc proto-oncogene protein
|
05169 Epstein-Barr virus infection [PATH:ko05169]
|
05165 Human papillomavirus infection [PATH:ko05165]
|
|
09171 Infectious disease: bacterial
|
05110 Vibrio cholerae infection [PATH:ko05110]
|
05120 Epithelial cell signaling in Helicobacter pylori infection [PATH:ko05120]
|
05130 Pathogenic Escherichia coli infection [PATH:ko05130]
|
05132 Salmonella infection [PATH:ko05132]
|
05131 Shigellosis [PATH:ko05131]
|
K13285 sipB, ipaB, bipB; invasin B
K06256 CD44; CD44 antigen
K13286 sipC, ipaC, bipC; invasin C
K13287 sipD, ipaD, bipD; invasin D
K06484 ITGA5, CD49e; integrin alpha 5
K05719 ITGB1, CD29; integrin beta 1
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K04438 CRK, CRKII; C-crk adapter molecule crk
K05726 BCAR1, CAS; breast cancer anti-estrogen resistance 1
K06106 CTTN, EMS1; cortactin
K05760 PXN; paxillin
K12366 ELMO1, CED12; engulfment and cell motility protein 1
K18985 ELMO2, CED12A; engulfment and cell motility protein 2
K13708 DOCK1; dedicator of cytokinesis protein 1
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K05753 WASF1; WAS protein family, member 1
K05748 WASF2; WAS protein family, member 2
K17260 ACTR2, ARP2; actin-related protein 2
K18584 ACTR3, ARP3; actin-related protein 3
K05757 ARPC1A_B; actin related protein 2/3 complex, subunit 1A/1B
K05758 ARPC2; actin related protein 2/3 complex, subunit 2
K05756 ARPC3; actin related protein 2/3 complex, subunit 3
K05755 ARPC4; actin related protein 2/3 complex, subunit 4
K05754 ARPC5; actin related protein 2/3 complex, subunit 5
K05692 ACTB_G1; actin beta/gamma 1
K04513 RHOA; Ras homolog gene family, member A
K05740 DIAPH1; diaphanous 1
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K10351 MYL2; myosin regulatory light chain 2
K12753 MYL5; myosin regulatory light chain 5
K12754 MYL7; myosin regulatory light chain 7
K12755 MYL9; myosin regulatory light chain 9
K12756 MYL10; myosin regulatory light chain 10
K12757 MYL12; myosin regulatory light chain 12
K12758 MYLPF; fast skeletal myosin light chain 2
K05699 ACTN1_4; actinin alpha 1/4
K06272 ILK; integrin-linked kinase [EC:2.7.11.1]
K06271 TLN; talin
K05700 VCL; vinculin
K04393 CDC42; cell division control protein 42
K13284 sipA, ipaA; invasin A
K13793 ospE, espO; secreted effector OspE
K13790 icsB, bopA; virulence protein IcsB
K13743 ipgB2; protein IpgB2
K13742 ipgB1; protein IpgB1
K12679 icsA, virG; outer membrane protein IcsA
K23612 WASL; neural Wiskott-Aldrich syndrome protein
K05759 PFN; profilin
K13085 ipgD, sopB; phosphatidylinositol-4,5-bisphosphate 4-phosphatase [EC:3.1.3.78]
K04361 EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K18441 CYTH; cytohesin
K07941 ARF6; ADP-ribosylation factor 6
K07937 ARF1_2; ADP-ribosylation factor 1/2
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07201 FOXO1; forkhead box protein O1
K09408 FOXO3; forkhead box protein O3
K12358 FOXO4; forkhead box protein O4
K17847 FOXO6; forkhead box protein O6
K08822 GSK3A; glycogen synthase kinase 3 alpha [EC:2.7.11.26]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05857 PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
K05860 PLCE; phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K05861 PLCZ; phosphatidylinositol phospholipase C, zeta [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K04281 CAST; calpastatin
K01367 CAPN1; calpain-1 [EC:3.4.22.52]
K03853 CAPN2; calpain-2 [EC:3.4.22.53]
K08583 CAPNS1, CAPN4; calpain, small subunit 1
K04728 ATM, TEL1; serine-protein kinase ATM [EC:2.7.11.1]
K04451 TP53, P53; tumor protein p53
K04570 BCL2L1, bcl-xL; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K02161 BCL2; apoptosis regulator Bcl-2
K12785 espG, virA; LEE-encoded effector EspG
K07345 fimA; major type 1 subunit fimbrin (pilin)
K00844 HK; hexokinase [EC:2.7.1.1]
K05862 VDAC1; voltage-dependent anion channel protein 1
K02159 BAX; apoptosis regulator BAX
K08738 CYC; cytochrome c
K15464 BNIP3; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
K05864 PPID, CYPD; peptidyl-prolyl isomerase D [EC:5.2.1.8]
K04394 CASP4, CASP11; caspase 4 [EC:3.4.22.57 3.4.22.64]
K04519 IL1B; interleukin 1 beta
K05482 IL18, IL1F4; interleukin 18
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A, TNFR1, CD120a; tumor necrosis factor receptor superfamily member 1A
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K09849 TRAF5; TNF receptor-associated factor 5
K02861 RIPK1, RIP1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
K04427 MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04403 MAP3K7IP1, TAB1; TAK1-binding protein 1
K04404 MAP3K7IP2, TAB2; TAK1-binding protein 2
K12793 MAP3K7IP3, TAB3; TAK1-binding protein 3
K07210 IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04467 IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02581 NFKBIB; NF-kappa-B inhibitor beta
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K10030 IL8, CXCL8; interleukin 8
K23826 TIFA; TRAF-interacting protein with FHA domain-containing protein A
K04386 IL1R1, CD121a; interleukin 1 receptor type I
K04391 CD14; monocyte differentiation antigen CD14
K10160 TLR4, CD284; toll-like receptor 4
K02406 fliC, hag; flagellin
K10168 TLR5; toll-like receptor 5
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K06068 PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
K18050 PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
K18052 PRKCQ; novel protein kinase C theta type [EC:2.7.11.13]
K07369 MALT1; mucosa-associated lymphoid tissue lymphoma translocation protein 1 [EC:3.4.22.-]
K07368 BCL10; B-cell CLL/lymphoma 10
K08727 NOD1, CARD4; nucleotide-binding oligomerization domain-containing protein 1
K12791 ARHGEF2, GEF-H1; Rho guanine nucleotide exchange factor 2
K08846 RIPK2; receptor-interacting serine/threonine-protein kinase 2 [EC:2.7.11.1]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K23827 ospI; glutamine deamidase
K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
K10580 UBE2N, BLU, UBC13; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
K23828 ipaH1.4_2.5; E3 ubiquitin-protein ligase IpaH1.4/2.5 [EC:2.3.2.27]
K10630 RBCK1, HOIL1; RanBP-type and C3HC4-type zinc finger-containing protein 1 [EC:2.3.2.31]
K11974 RNF31, HOIP; E3 ubiquitin-protein ligase RNF31 [EC:2.3.2.31]
K20894 SHARPIN; shank-associated RH domain-interacting protein
K23654 nleE, ospZ; T3SS secreted effector NleE
K23829 TNIP1, ABIN1; TNFAIP3-interacting protein 1
K13791 ipaH9.8; invasion plasmid antigen
K13792 ospG; secreted effector OspG
K06689 UBE2D, UBC4, UBC5; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
K03868 RBX1, ROC1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
K03347 CUL1, CDC53; cullin 1
K03094 SKP1, CBF3D; S-phase kinase-associated protein 1
K03362 FBXW1_11, BTRC, beta-TRCP; F-box and WD-40 domain protein 1/11
K23830 ipaH4.5; E3 ubiquitin-protein ligase IpaH4.5 [EC:2.3.2.27]
K23831 ipaH0722; E3 ubiquitin-protein ligase IpaH0722 [EC:2.3.2.27]
K17834 CGAS, MB21D1; cyclic GMP-AMP synthase [EC:2.7.7.86]
K12654 STING1, TMEM173, MITA; stimulator of interferon genes protein
K04729 MYD88; myeloid differentiation primary response protein MyD88
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K05411 IRF3; interferon regulatory factor 3
K05415 IFNB; interferon beta
K23832 ipaJ; cysteine protease IpaJ [EC:3.4.22.-]
K12836 U2AF1; splicing factor U2AF 35 kDa subunit
K12499 CCL5; C-C motif chemokine 5
K05427 CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
K04371 ERK, MAPK1_3; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04445 RPS6KA5, MSK1; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
K11253 H3; histone H3
K11586 CBX3, HP1G; chromobox protein 3
K13450 ospF, mkaD, spvC; phosphothreonine lyase [EC:4.2.3.-]
K08334 BECN, VPS30, ATG6; beclin
K17889 ATG14L, ATG14; beclin 1-associated autophagy-related key regulator
K08333 PIK3R4, VPS15; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]
K00914 PIK3C3, VPS34; phosphatidylinositol 3-kinase [EC:2.7.1.137]
K16185 RRAGA_B; Ras-related GTP-binding protein A/B
K16186 RRAGC_D; Ras-related GTP-binding protein C/D
K07203 MTOR, FRAP, TOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K07204 RAPTOR; regulatory associated protein of mTOR
K16184 AKT1S1, PRAS40; proline-rich AKT1 substrate 1
K17890 ATG16L1; autophagy-related protein 16-1
K08339 ATG5; autophagy-related protein 5
K08336 ATG12; ubiquitin-like protein ATG12
K10435 MAP1LC; microtubule-associated protein 1 light chain
K03990 C3; complement component 3
K14381 SQSTM1; sequestosome 1
K21348 CALCOCO2, NDP52; calcium-binding and coiled-coil domain-containing protein 2
K02927 RP-L40e, RPL40, UBA52; ubiquitin-large subunit ribosomal protein L40e
K02977 RP-S27Ae, RPS27A, UBA80; ubiquitin-small subunit ribosomal protein S27Ae
K04551 UBB; ubiquitin B
K08770 UBC; ubiquitin C
K16942 SEPT2; septin 2
K16938 SEPT3_9_12; septin 3/9/12
K16939 SEPT6_8_11; septin 6/8/11
K16944 SEPT7, CDC3; septin 7
K17908 WIPI1_2, ATG18; autophagy-related protein 18
K17988 TECPR1; tectonin beta-propeller repeat-containing protein 1
K20121 FNBP1; formin-binding protein 1
K13520 icsP, sopA; outer membrane protease [EC:3.4.23.-]
K23833 ospC; secreted effector OspC
K11006 stxA; shiga toxin subunit A
K11007 stxB; shiga toxin subunit B
K11011 set1A; enterotoxin Set1A
K11012 set1B; enterotoxin Set1B
K23345 GLMN; glomulin
K12800 NLRP3, PYPAF1; NACHT, LRR and PYD domains-containing protein 3
K22487 prgJ; type III secretion system protein
K12807 NAIP, BIRC1; baculoviral IAP repeat-containing protein 1
K03221 yscF, sctF, ssaG, prgI; type III secretion protein F
K12805 NLRC4, CARD12; NLR family CARD domain-containing protein 4
K12799 PYCARD, ASC; apoptosis-associated speck-like protein containing a CARD
K01370 CASP1; caspase 1 [EC:3.4.22.36]
K23834 ipaH7.8; E3 ubiquitin-protein ligase IpaH7.8 [EC:2.3.2.27]
|
05135 Yersinia infection [PATH:ko05135]
|
05133 Pertussis [PATH:ko05133]
|
05134 Legionellosis [PATH:ko05134]
|
05150 Staphylococcus aureus infection [PATH:ko05150]
|
05152 Tuberculosis [PATH:ko05152]
|
05100 Bacterial invasion of epithelial cells [PATH:ko05100]
|
|
09174 Infectious disease: parasitic
|
05146 Amoebiasis [PATH:ko05146]
|
K08570 EHCP; histolysain [EC:3.4.22.35]
K04519 IL1B; interleukin 1 beta
K04386 IL1R1, CD121a; interleukin 1 receptor type I
K04387 IL1R2, CD121b; interleukin 1 receptor type II
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04455 HSPB1; heat shock protein beta-1
K10955 MUC2; mucin-2
K06236 COL1A; collagen type I alpha
K06237 COL4A; collagen type IV alpha
K05717 FN1; fibronectin 1
K05637 LAMA1_2; laminin, alpha 1/2
K06240 LAMA3_5; laminin, alpha 3/5
K06241 LAMA4; laminin, alpha 4
K05636 LAMB1; laminin, beta 1
K06243 LAMB2; laminin, beta 2
K06244 LAMB3; laminin, beta 3
K06245 LAMB4; laminin, beta 4
K05635 LAMC1; laminin, gamma 1
K06246 LAMC2; laminin, gamma 2
K06247 LAMC3; laminin, gamma 3
K13968 CP112; cysteine proteinase
K13969 ADH112; adhesin
K13970 HGL; galactose-inhibitable lectin heavy subunit
K13971 LGL; galactose-inhibitable lectin light subunit
K13972 IGL; galactose-inhibitable lectin intermediate subunit
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K13973 AP; pore-forming peptide ameobapore
K06856 IGH; immunoglobulin heavy chain
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K04636 GNA14; guanine nucleotide-binding protein subunit alpha-14
K04637 GNA15; guanine nucleotide-binding protein subunit alpha-15
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K13974 EHCBP; calcium-binding protein
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K04633 GNAL; guanine nucleotide-binding protein G(olf) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K13975 PATMK; phagosome-associated TMK96
K07887 RAB5A; Ras-related protein Rab-5A
K07888 RAB5B; Ras-related protein Rab-5B
K07889 RAB5C; Ras-related protein Rab-5C
K07897 RAB7A; Ras-related protein Rab-7A
K07898 RAB7B; Ras-related protein Rab-7B
K10159 TLR2, CD282; toll-like receptor 2
K10160 TLR4, CD284; toll-like receptor 4
K04391 CD14; monocyte differentiation antigen CD14
K05405 IL6; interleukin 6
K05505 CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
K05427 CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
K10030 IL8, CXCL8; interleukin 8
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K06448 CD1; T-cell surface glycoprotein CD1
K04687 IFNG; interferon gamma
K19720 COL3A; collagen type III alpha
K05725 PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]
K13976 EHPAK; p21-activated kinase
K13977 EHLIMA; LIM domain-containing protein
K05700 VCL; vinculin
K05699 ACTN1_4; actinin alpha 1/4
K01476 E3.5.3.1, rocF, arg; arginase [EC:3.5.3.1]
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
K04072 adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1]
K06464 ITGB2, CD18; integrin beta 2
K06461 ITGAM, CD11b; integrin alpha M
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K13279 PRDX1; peroxiredoxin 1 [EC:1.11.1.24]
K13963 SERPINB; serpin B
K01319 CTSG; cathepsin G [EC:3.4.21.20]
K13978 ACTNL; actinin-like protein
K05443 IL10, CSIF; interleukin 10
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K03997 C8A; complement component 8 subunit alpha
K03998 C8B; complement component 8 subunit beta
K03999 C8G; complement component 8 subunit gamma
K04000 C9; complement component 9
K23601 SREHP; serine-rich protein
K23602 EhSTIRP; serine-threonine-isoleucine rich protein
|
05144 Malaria [PATH:ko05144]
|
05145 Toxoplasmosis [PATH:ko05145]
|
05140 Leishmaniasis [PATH:ko05140]
|
05142 Chagas disease [PATH:ko05142]
|
05143 African trypanosomiasis [PATH:ko05143]
|
|
09163 Immune disease
|
05310 Asthma [PATH:ko05310]
|
05322 Systemic lupus erythematosus [PATH:ko05322]
|
05323 Rheumatoid arthritis [PATH:ko05323]
|
K05412 CD80; CD80 antigen
K05413 CD86; CD86 antigen
K06470 CD28; CD28 antigen
K06538 CTLA4, CD152; cytotoxic T-lymphocyte-associated protein 4
K06752 MHC2; MHC class II antigen
K10784 TRAV; T cell receptor alpha chain V region
K10785 TRBV; T-cell receptor beta chain V region
K05718 ITGAL, CD11a; integrin alpha L
K06464 ITGB2, CD18; integrin beta 2
K06490 ICAM1, CD54; intercellular adhesion molecule 1
K05433 IL15; interleukin 15
K05475 TNFSF13, APRIL, CD256; tumor necrosis factor ligand superfamily member 13
K05476 TNFSF13B, TNFSF20, CD257; tumor necrosis factor ligand superfamily member 13B
K06856 IGH; immunoglobulin heavy chain
K03157 LTB, TNFC; lymphotoxin beta (TNF superfamily, member 3)
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
K05405 IL6; interleukin 6
K05417 IL11; interleukin 11
K05482 IL18, IL1F4; interleukin 18
K10159 TLR2, CD282; toll-like receptor 2
K10160 TLR4, CD284; toll-like receptor 4
K04448 JUN; transcription factor AP-1
K04379 FOS; proto-oncogene protein c-fos
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K05426 IL23A; interleukin 23 subunit alpha
K05489 IL17A, CTLA8; interleukin 17A
K05261 PTH; parathyroid hormone
K05453 CSF1, MCSF; macrophage colony-stimulating factor 1
K05473 TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
K05147 TNFRSF11A, RANK, CD265; tumor necrosis factor receptor superfamily member 11A
K02145 ATPeV1A, ATP6A; V-type H+-transporting ATPase subunit A [EC:7.1.2.2]
K02147 ATPeV1B, ATP6B; V-type H+-transporting ATPase subunit B
K02148 ATPeV1C, ATP6C; V-type H+-transporting ATPase subunit C
K02149 ATPeV1D, ATP6M; V-type H+-transporting ATPase subunit D
K02150 ATPeV1E, ATP6E; V-type H+-transporting ATPase subunit E
K02151 ATPeV1F, ATP6S14; V-type H+-transporting ATPase subunit F
K02152 ATPeV1G, ATP6G; V-type H+-transporting ATPase subunit G
K02153 ATPeV0E, ATP6H; V-type H+-transporting ATPase subunit e
K02154 ATPeV0A, ATP6N; V-type H+-transporting ATPase subunit a
K02146 ATPeV0D, ATP6D; V-type H+-transporting ATPase subunit d
K02144 ATPeV1H; V-type H+-transporting ATPase subunit H
K03662 ATPeVS1, ATP6S1; V-type H+-transporting ATPase S1 subunit
K02155 ATPeV0C, ATP6L; V-type H+-transporting ATPase 16kDa proteolipid subunit
K03661 ATPeV0B, ATP6F; V-type H+-transporting ATPase 21kDa proteolipid subunit
K01371 CTSK; cathepsin K [EC:3.4.22.38]
K14379 ACP5; tartrate-resistant acid phosphatase type 5 [EC:3.1.3.2]
K01388 MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
K01394 MMP3; matrix metalloproteinase-3 (stromelysin 1, progelatinase) [EC:3.4.24.17]
K01365 CTSL; cathepsin L [EC:3.4.22.15]
K05427 CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
K12499 CCL5; C-C motif chemokine 5
K14624 CCL2, MCP1; C-C motif chemokine 2
K05408 CCL3; C-C motif chemokine 3
K14625 CCL20; C-C motif chemokine 20
K05505 CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
K05506 CXCL5_6, SCYB5_6; C-X-C motif chemokine 5/6
K10030 IL8, CXCL8; interleukin 8
K10031 CXCL12; C-X-C motif chemokine 12
K05448 VEGFA; vascular endothelial growth factor A
K05096 FLT1, VEGFR1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
K05465 ANGPT1; angiopoietin 1
K05121 TEK, TIE2, CD202; endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]
K04687 IFNG; interferon gamma
|
05320 Autoimmune thyroid disease [PATH:ko05320]
|
05321 Inflammatory bowel disease [PATH:ko05321]
|
05330 Allograft rejection [PATH:ko05330]
|
05332 Graft-versus-host disease [PATH:ko05332]
|
05340 Primary immunodeficiency [PATH:ko05340]
|
|
09164 Neurodegenerative disease
|
|
09165 Substance dependence
|
|
09166 Cardiovascular disease
|
|
09167 Endocrine and metabolic disease
|
|
09175 Drug resistance: antimicrobial
|
|
09176 Drug resistance: antineoplastic
|
|
09180 Brite Hierarchies
|
|
09181 Protein families: metabolism
|
|
09182 Protein families: genetic information processing
|
03000 Transcription factors [BR:ko03000]
|
03021 Transcription machinery [BR:ko03021]
|
03019 Messenger RNA biogenesis [BR:ko03019]
|
K00565 RNMT; mRNA (guanine-N7-)-methyltransferase [EC:2.1.1.56]
K13917 RNGTT; mRNA-capping enzyme [EC:2.7.7.50 3.6.1.74]
K04563 CDC28, CDC2; cyclin-dependent kinase [EC:2.7.11.22]
K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
K00987 CEG1; mRNA guanylyltransferase [EC:2.7.7.50]
K01098 CET1; polynucleotide 5'-triphosphatase [EC:3.6.1.74]
K14589 CMTR1, FTSJD2, MTR1; cap1 methyltransferase [EC:2.1.1.57]
K14590 CMTR2, FTSJD1, AFT; cap2 methyltransferase [EC:2.1.1.296]
K18776 MTR2, MT48; cap2 methyltransferase [EC:2.1.1.296]
K18777 MTR3, MT57; cap3/cap4 methyltransferase [EC:2.1.1.-]
K18708 FAM103A1; RNMT-activating mini protein
K12882 NCBP1, CBP80; nuclear cap-binding protein subunit 1
K12883 NCBP2, CBP20; nuclear cap-binding protein subunit 2
K14397 NUDT21, CPSF5, CFIM25; cleavage and polyadenylation specificity factor subunit 5
K14398 CPSF6_7; cleavage and polyadenylation specificity factor subunit 6/7
K14399 CLP1, HERB; polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78]
K14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11
K14401 CPSF1, CFT1; cleavage and polyadenylation specificity factor subunit 1
K14402 CPSF2, CFT2; cleavage and polyadenylation specificity factor subunit 2
K14403 CPSF3, YSH1; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]
K14404 CPSF4, YTH1; cleavage and polyadenylation specificity factor subunit 4
K14405 FIP1L1, FIP1; pre-mRNA 3'-end-processing factor FIP1
K15541 MPE1; protein MPE1
K15542 PFS2; polyadenylation factor subunit 2
K14962 WDR82, SWD2, CPS35; COMPASS component SWD2
K15543 REF2; RNA end formation protein 2
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]
K14406 CSTF1; cleavage stimulation factor subunit 1
K14407 CSTF2, RNA15; cleavage stimulation factor subunit 2
K14408 CSTF3, RNA14; cleavage stimulation factor subunit 3
K06100 SYMPK; symplekin
K11086 SNRPB, SMB; small nuclear ribonucleoprotein B and B'
K11088 SNRPD3, SMD3; small nuclear ribonucleoprotein D3
K11097 SNRPE, SME; small nuclear ribonucleoprotein E
K11098 SNRPF, SMF; small nuclear ribonucleoprotein F
K11099 SNRPG, SMG; small nuclear ribonucleoprotein G
K25591 LSM10; U7 snRNA-associated Sm-like protein LSm10
K25592 LSM11; U7 snRNA-associated Sm-like protein LSm11
K18710 SLBP; histone RNA hairpin-binding protein
K25593 CASP8AP2; CASP8-associated protein 2
K15171 SUPT4H1, SPT4; transcription elongation factor SPT4
K15172 SUPT5H, SPT5; transcription elongation factor SPT5
K05925 METTL3; mRNA m6A methyltransferase catalytic subunit [EC:2.1.1.348]
K23960 METTL14; mRNA m6A methyltransferase non-catalytic subunit
K24174 METTL4; N(6)-adenine-specific DNA methyltransferase [EC:2.1.1.72]
K11393 METTL16, METT10D; U6 snRNA m6A methyltransferase [EC:2.1.1.346]
K22824 WTAP; pre-mRNA-splicing regulator WTAP
K22910 VIRMA; protein virilizer
K13190 RBM15; RNA-binding protein 15
K22909 ZC3H13; zinc finger CCCH domain-containing protein 13
K15685 CBLL1; E3 ubiquitin-protein ligase Hakai [EC:2.3.2.27]
K14376 PAP; poly(A) polymerase [EC:2.7.7.19]
K14079 PAPD4, GLD2; poly(A) RNA polymerase GLD2 [EC:2.7.7.19]
K18709 TUT1; speckle targeted PIP5K1A-regulated poly(A) polymerase [EC:2.7.7.19 2.7.7.52]
K10683 BARD1; BRCA1-associated RING domain protein 1
K13192 RBM26; RNA-binding protein 26
K19469 FTO; mRNA N6-methyladenine demethylase [EC:1.14.11.53]
K10767 ALKBH5; mRNA N6-methyladenine demethylase [EC:1.14.11.53]
K23600 TARDBP, TDP43; TAR DNA-binding protein 43
K18711 DHX40; ATP-dependent RNA helicase DHX40 [EC:5.6.2.6]
K13102 KIN; DNA/RNA-binding protein KIN17
K24975 METTL8; mRNA N(3)-methylcytidine methyltransferase METTL8 [EC:2.1.1.-]
K23040 METTL22; methyltransferase-like protein 22 [EC:2.1.1.-]
K23033 TENT5A_B, FAM46A_B; terminal nucleotidyltransferase 5A/B [EC:2.7.7.-]
K23034 TENT5C, FAM46C; terminal nucleotidyltransferase 5C [EC:2.7.7.19]
K23035 TENT5D, FAM46D; terminal nucleotidyltransferase 5D [EC:2.7.7.19]
K23038 ZC3H14; zinc finger CCCH domain-containing protein 14
K27103 SRRT, ARS2; serrate RNA effector molecule
K23039 NAB2; nuclear polyadenylated RNA-binding protein NAB2
K12876 RBM8A, Y14; RNA-binding protein 8A
K12877 MAGOH; protein mago nashi
K12881 THOC4, ALY; THO complex subunit 4
K12812 DDX39B, UAP56, SUB2; ATP-dependent RNA helicase UAP56/SUB2 [EC:5.6.2.7]
K13025 EIF4A3, FAL1; ATP-dependent RNA helicase [EC:5.6.2.7]
K25178 CCDC174; coiled-coil domain-containing protein 174
K14323 CASC3, MLN51; protein CASC3
K14324 SAP18; histone deacetylase complex subunit SAP18
K13114 PNN; pinin
K12875 ACIN1, ACINUS; apoptotic chromatin condensation inducer in the nucleus
K14325 RNPS1; RNA-binding protein with serine-rich domain 1
K13171 SRRM1, SRM160; serine/arginine repetitive matrix protein 1
K12878 THOC1; THO complex subunit 1
K12879 THOC2; THO complex subunit 2
K12880 THOC3; THO complex subunit 3
K13174 THOC5; THO complex subunit 5
K13175 THOC6; THO complex subunit 6
K13176 THOC7; THO complex subunit 7
K18712 HPR1; THO complex subunit HPR1
K18713 THP2; THO complex subunit THP2
K18714 MFT1; THO complex subunit MFT1
K23801 PCID2, THP1; nuclear mRNA export protein PCID2/THP1
K10881 SHFM1, DSS1, RPN15; 26 proteasome complex subunit DSS1
K11368 ENY2, DC6, SUS1; enhancer of yellow 2 transcription factor
K10840 CETN2; centrin-2
K16466 CETN3, CDC31; centrin-3
K24317 MCM3AP; germinal-center associated nuclear protein [EC:2.3.1.48]
K23719 SAC3; nuclear mRNA export protein SAC3
K09291 TPR, MLP1, MLP2; nucleoprotein TPR
K14298 RAE1, GLE2; mRNA export factor
K14004 SEC13; protein transport protein SEC13
K14302 NUP37; nuclear pore complex protein Nup37
K14304 NUP85; nuclear pore complex protein Nup85
K14305 NUP43; nuclear pore complex protein Nup43
K14295 NUP50, NPAP60; nuclear pore complex protein Nup50
K14308 NUP54, NUP57; nuclear pore complex protein Nup54
K14306 NUP62, NSP1; nuclear pore complex protein Nup62
K14318 NUP88; nuclear pore complex protein Nup88
K14309 NUP93, NIC96; nuclear pore complex protein Nup93
K14297 NUP98, ADAR2, NUP116; nuclear pore complex protein Nup98-Nup96
K14301 NUP107, NUP84; nuclear pore complex protein Nup107
K14300 NUP133; nuclear pore complex protein Nup133
K14311 NUP188; nuclear pore complex protein Nup188
K14296 NUP153; nuclear pore complex protein Nup153
K14312 NUP155, NUP170, NUP157; nuclear pore complex protein Nup155
K14303 NUP160, NUP120; nuclear pore complex protein Nup160
K14313 NUP35, NUP53; nuclear pore complex protein Nup53
K14310 NUP205, NUP192; nuclear pore complex protein Nup205
K14314 NUP210, GP210; nuclear pore complex protein Nup210
K14317 NUP214, CAN; nuclear pore complex protein Nup214
K14316 POM121, NUP121; nuclear pore complex protein Nup121
K14307 NUPL1, NUP49; nucleoporin p58/p45
K14321 NUPL2, NUP42, CG1; nucleoporin-like protein 2
K14315 NDC1, TMEM48; nucleoporin NDC1
K14299 SEH1; nucleoporin SEH1
K12172 RANBP2, NUP358; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]
K03345 SENP2, AXAM2; sentrin-specific protease 2 (axin associating molecule) [EC:3.4.22.68]
K14320 AAAS; aladin
K18715 NUP159; nucleoporin NUP159
K18716 NUP42, RIP1; nucleoporin NUP42
K18717 ASM4, NUP59; nucleoporin ASM4
K18718 NUP60; nucleoporin NUP60
K18719 NUP82; nucleoporin NUP82
K18720 NUP145; nucleoporin NUP145
K18721 NUP1; nucleoporin NUP1
K18722 NUP2; nucleoporin NUP2
K18723 GLE1; nucleoporin GLE1
K14284 NXF, TAP, MEX67; nuclear RNA export factor
K14285 NXT1_2, P15; NTF2-related export protein 1/2
K26564 NPAP1; nuclear pore-associated protein 1
K14543 MTR2; mRNA transport regulator MTR2
K18724 POM34; nucleoporin POM34
K18725 POM152; nucleoporin POM152
K14017 SNL1; HSP70 co-chaperone SNL1
K07936 RAN; GTP-binding nuclear protein Ran
K18646 ANP32A_C_D; acidic leucine-rich nuclear phosphoprotein 32 family member A/C/D
K18647 ANP32B; acidic leucine-rich nuclear phosphoprotein 32 family member B
K05475 TNFSF13, APRIL, CD256; tumor necrosis factor ligand superfamily member 13
K13088 ELAVL1, HUR; ELAV-like protein 1
K13208 ELAVL2_3_4; ELAV like protein 2/3/4
K18726 FAF2, UBXD8; FAS-associated factor 2
K13525 VCP, CDC48; transitional endoplasmic reticulum ATPase
K21806 VCPKMT, METTL21D; protein N-lysine methyltransferase METTL21D [EC:2.1.1.-]
K18727 TNPO2, IPO3, KPNB2B; transportin-2
K14290 XPO1, CRM1; exportin-1
K18460 XPO7, EXP7; exportin-7
K24115 RANBP17; Ran-binding protein 17
K14319 RANGAP1; Ran GTPase-activating protein 1
K14651 TAF15, NPL3; transcription initiation factor TFIID subunit 15
K03259 EIF4E; translation initiation factor 4E
K03257 EIF4A; translation initiation factor 4A
K03260 EIF4G; translation initiation factor 4G
K03258 EIF4B; translation initiation factor 4B
K24086 EIF4H; translation initiation factor 4H
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K18644 EIF4EBP2; eukaryotic translation initiation factor 4E binding protein 2
K18645 EIF4EBP3; eukaryotic translation initiation factor 4E binding protein 3
K18728 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter
K18729 ANGEL; protein angel
K15516 FMR; fragile X mental retardation protein
K05749 CYFIP; cytoplasmic FMR1 interacting protein
K13133 GEMIN5; gem associated protein 5
K14283 TACC3, maskin; transforming acidic coiled-coil-containing protein 3
K02602 CPEB, ORB; cytoplasmic polyadenylation element-binding protein
K11594 DDX3X, bel; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein
K13126 PABPC; polyadenylate-binding protein
K14322 PAIP1; polyadenylate-binding protein-interacting protein 1
K27470 PAIP2; polyadenylate-binding protein-interacting protein 2
K12599 SKI2, SKIV2L; antiviral helicase SKI2 [EC:5.6.2.6]
K18664 SLH1; antiviral helicase SLH1 [EC:5.6.2.6]
K23041 DEAF1; deformed epidermal autoregulatory factor 1
K07575 MCTS, TMA20; malignant T-cell-amplified sequence
K24272 DENR, TMA22; density-regulated protein
K16932 APOBEC1; C->U-editing enzyme APOBEC1 [EC:3.5.4.36]
K24978 A1CF; APOBEC1 complementation factor
K14294 WIBG, PYM; partner of Y14 and mago
K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
K14411 MSI; RNA-binding protein Musashi
K14416 HBS1; elongation factor 1 alpha-like protein
K06965 PELO, DOM34, pelA; protein pelota
K14396 PABPN1, PABP2; polyadenylate-binding protein 2
K18731 GFD1; mRNA transport factor GFD1
K18655 DDX19, DBP5; ATP-dependent RNA helicase DDX19/DBP5 [EC:5.6.2.7]
K18656 DDX25, GRTH; ATP-dependent RNA helicase DDX25 [EC:5.6.2.7]
K12867 SYF1, XAB2; pre-mRNA-splicing factor SYF1
K18732 SARNP, CIP29, THO1; SAP domain-containing ribonucleoprotein
K11493 RCC1; regulator of chromosome condensation
K18733 LARP6; la-related protein 6
K21772 PURA; transcriptional activator protein Pur-alpha
K21799 PURB; transcriptional activator protein Pur-beta
K22414 POLDIP3; polymerase delta-interacting protein 3
K22415 ZC3H11; zinc finger CCCH domain-containing protein 11
K23802 LENG8, THP3; SAC3 family protein LENG8/THP3
K24823 PATL2; protein PAT1 homolog 2
K23799 YRA2; RNA annealing protein YRA2
K03265 ETF1, ERF1; peptide chain release factor subunit 1
K03267 ERF3, GSPT; peptide chain release factor subunit 3
K14326 UPF1, RENT1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]
K14327 UPF2, RENT2; regulator of nonsense transcripts 2
K14328 UPF3, RENT3; regulator of nonsense transcripts 3
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1]
K11125 SMG5, EST1B; protein SMG5
K11124 SMG6, EST1A; protein SMG6 [EC:3.1.-.-]
K14409 SMG7, EST1C; protein SMG7
K18734 SMG8; protein SMG8
K18735 SMG9; protein SMG9
K19539 SECISBP2, SBP2; selenocysteine insertion sequence-binding protein 2
K20101 DHX34; ATP-dependent RNA helicase DHX34 [EC:5.6.2.6]
K24887 GTPBP1; GTP-binding protein 1
K18736 SHE2; SWI5-dependent HO expression protein 2
K18737 SHE3; SWI5-dependent HO expression protein 3
K14844 PUF6; pumilio homology domain family member 6
K18738 HEK; heterogeneous nuclear rnp K-like protein
K10357 MYO5; myosin V
K18658 ASH1; transcriptional regulatory protein ASH1
K18739 BICD; protein bicaudal D
K18740 EXD1, EGL; exonuclease 3'-5' domain-containing protein 1
K05692 ACTB_G1; actin beta/gamma 1
K17269 MBP; myelin basic protein
K07606 VIM; vimentin
K14739 MT1_2; metallothionein 1/2
K04377 MYC; Myc proto-oncogene protein
K18659 BCD; homeotic protein bicoid
K05495 GDF1; growth differentiation factor 1
K10180 TBX6; T-box protein 6
K18741 NANOS1, NOS1; protein nanos 1
K18742 OSK; maternal effect protein oskar
K02524 K10; DNA binding protein (fs(1)K10, female sterile(1)K10)
K02447 GRK; protein gruken
K09090 HESN; hairy and enhancer of split, invertebrate
K12965 ZBP1, DAI; Z-DNA binding protein 1
K13210 FUBP; far upstream element-binding protein
K03231 EEF1A; elongation factor 1-alpha
K03233 EEF1G; elongation factor 1-gamma
K13158 HNRNPA2B1; heterogeneous nuclear ribonucleoprotein A2/B1
K16220 HAX1; HCLS1-associated protein X-1
K15044 AGFG1; Arf-GAP domain and FG repeats-containing protein 1
K17597 STAU; double-stranded RNA-binding protein Staufen
K13197 IGF2BP3; insulin-like growth factor 2 mRNA-binding protein 3
K13218 PTBP1, PTB; polypyrimidine tract-binding protein 1
K03102 SQD; squid
K13162 PCBP2; poly(rC)-binding protein 2
K21444 PCBP3_4; poly(rC)-binding protein 3/4
K18743 CAPRIN1, GPIAP1; caprin-1
K18744 CAPRIN2, EEG1; caprin-2
K02177 BRU; bruno
K18745 EXU; maternal protein exuperantia
K09276 YBX1, NSEP1; Y-box-binding protein 1
K18746 CUP; protein cup
K18747 SXL; protein sex-lethal
K18748 SSD1; protein SSD1
K12618 XRN1, SEP1, KEM1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
K11593 ELF2C, AGO; eukaryotic translation initiation factor 2C
K17642 DDX3Y; ATP-dependent RNA helicase DDX3Y [EC:5.6.2.7]
K12614 DDX6, RCK, DHH1; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7]
K15686 MEX3, RKHD; RNA-binding protein MEX3 [EC:2.3.2.27]
K08290 FASTK; Fas-activated serine/threonine kinase [EC:2.7.11.8]
K18749 LSM14, RAP55, SCD6; protein LSM14
K12889 PCBP1; poly(rC)-binding protein 1
K16682 AJUBA, LIMD1, WTIP; LIM domain-containing protein
K18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]
K18422 MOV10; helicase MOV-10 [EC:5.6.2.5]
K18751 PNRC2; proline-rich nuclear receptor coactivator 2
K18752 TNPO1, IPO2, KPNB2; transportin-1
K15308 TTP; tristetraprolin
K18753 ZFP36L; butyrate response factor
K18754 LIN28; protein lin-28
K04533 HD; huntingtin
K18755 IPO8, RANBP8; importin-8
K18756 BICC1, BICC; protein bicaudal C
K04345 PKA; protein kinase A [EC:2.7.11.11]
K18757 LARP1; la-related protein 1
K23625 ATXN2_2L; ataxin 2/2L
K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]
K12610 DCP1A; mRNA-decapping enzyme 1A [EC:3.-.-.-]
K12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]
K12612 DCP1; mRNA-decapping enzyme subunit 1
K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1
K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2
K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3
K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4
K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5
K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6
K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7
K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8
K10407 KLC; kinesin light chain
K07374 TUBA; tubulin alpha
K18412 TNRC6, GW182; trinucleotide repeat-containing gene 6 protein
K12604 CNOT1, NOT1; CCR4-NOT transcription complex subunit 1
K12605 CNOT2, NOT2; CCR4-NOT transcription complex subunit 2
K12580 CNOT3, NOT3; CCR4-NOT transcription complex subunit 3
K10643 CNOT4, NOT4, MOT2; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
K12603 CNOT6, CCR4; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
K12581 CNOT7_8, CAF1, POP2; CCR4-NOT transcription complex subunit 7/8
K26671 GARRE1; granule associated Rac and RHOG effector protein 1
K18758 DIS3L2; DIS3-like exonuclease 2 [EC:3.1.13.-]
K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]
K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3
K14443 TOB; protein Tob/BTG
K12617 PATL1, PAT1; DNA topoisomerase 2-associated protein PAT1
K18759 EDC1_2; enhancer of mRNA-decapping protein 1/2
K12615 EDC3; enhancer of mRNA-decapping protein 3
K12616 EDC4; enhancer of mRNA-decapping protein 4
K18760 NANOS2, NOS2; protein nanos 2
K18761 NANOS3, NOS3; protein nanos 3
K10651 TRIM21, SSA1; tripartite motif-containing protein 21 [EC:2.3.2.27]
K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
K03015 RPB7, POLR2G; DNA-directed RNA polymerase II subunit RPB7
K16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
K18762 ZAR1; zygote arrest protein 1
K20102 YTHDF; YTH domain-containing family protein
K13201 TIA1, TIAL1; nucleolysin TIA-1/TIAR
K17265 G3BP1; Ras GTPase-activating protein-binding protein 1 [EC:5.6.2.5 5.6.2.3]
K24983 G3BP2; Ras GTPase-activating protein-binding protein 2
K15026 EIF2A; translation initiation factor 2A
K03253 EIF3B; translation initiation factor 3 subunit B
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K14753 RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98]
K18404 TDRD3; tudor domain-containing protein 3
K18763 LARP4; la-related protein 4
K12619 XRN2, RAT1; 5'-3' exoribonuclease 2 [EC:3.1.13.-]
K20553 XRN4; 5'-3' exoribonuclease 4 [EC:3.1.13.-]
K16855 NUDT16; U8 snoRNA-decapping enzyme [EC:3.6.1.62 3.6.1.64]
K12584 DCPS, DCS; m7GpppX diphosphatase [EC:3.6.1.59]
K25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-]
K07573 CSL4, EXOSC1; exosome complex component CSL4
K03679 RRP4, EXOSC2; exosome complex component RRP4
K03681 RRP40, EXOSC3; exosome complex component RRP40
K11600 RRP41, EXOSC4, SKI6; exosome complex component RRP41
K12590 RRP46, EXOSC5; exosome complex component RRP46
K12587 MTR3, EXOSC6; exosome complex component MTR3
K12589 RRP42, EXOSC7; exosome complex component RRP42
K12586 RRP43, EXOSC8, OIP2; exosome complex component RRP43
K03678 RRP45, EXOSC9; exosome complex component RRP45
K12585 DIS3, RRP44; exosome complex exonuclease DIS3/RRP44 [EC:3.1.13.-]
K18681 DIS3L; DIS3-like exonuclease 1 [EC:3.1.13.-]
K12591 RRP6, EXOSC10; exosome complex exonuclease RRP6 [EC:3.1.13.-]
K12592 C1D, LRP1; exosome complex protein LRP1
K12593 MPHOSPH6, MPP6; M-phase phosphoprotein 6, animal type
K12594 MPP6; M-phase phosphoprotein 6, fungi type
K12595 SKI7; superkiller protein 7
K20103 DDX60; ATP-dependent RNA helicase DDX60 [EC:5.6.2.7]
K03514 PAPD5_7, TRF4; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19]
K12597 AIR1_2; protein AIR1/2
K12598 MTR4, SKIV2L2; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6]
K12596 TRF5; poly(A) RNA polymerase
K12600 SKI3, TTC37; superkiller protein 3
K12601 SKI8; superkiller protein 8
K12602 WDR61, REC14, SKI8; WD repeat-containing protein 61
K12606 RCD1, CNOT9, CAF40; CCR4-NOT transcription complex subunit 9
K12607 CNOT10; CCR4-NOT transcription complex subunit 10
K12608 CAF16; CCR4-NOT complex subunit CAF16
K12609 CAF120; CCR4-NOT transcriptional complex subunit CAF120
K01148 PARN, PNLDC1; poly(A)-specific ribonuclease [EC:3.1.13.4]
K14442 DHX36, RHAU; ATP-dependent RNA helicase DHX36 [EC:5.6.2.6]
K05427 CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
K18764 NOCT, CCRN4L; nocturnin [EC:3.1.3.108]
K18416 THEX1, ERI1; 3'-5' exoribonuclease 1 [EC:3.1.-.-]
K18417 ERI2; ERI1 exoribonuclease 2 [EC:3.1.-.-]
K19612 PDE12; 2',5'-phosphodiesterase [EC:3.1.13.4 3.1.4.-]
K22416 IREB2; iron-responsive element-binding protein 2
K25165 HELZ2; 3'-5' exoribonuclease HELZ2 [EC:3.1.13.1 5.6.2.6]
K26109 NRDE2; nuclear exosome regulator NRDE2
K27396 SMG; protein Smaug
K27498 FOCAD; focadhesin
K27407 VTS1; RNA-binding protein VTS1
K01168 RNASE1_2; pancreatic ribonuclease [EC:4.6.1.18]
K10787 RNASE3, ECP; eosinophil cationic protein [EC:3.1.27.-]
K16632 RNASE4; ribonuclease 4 [EC:3.1.27.-]
K01172 RNASE6_7_8; ribonuclease 6/7/8 [EC:3.1.27.-]
K16633 RNASE11; ribonuclease 11 [EC:3.1.27.-]
K18668 ZC3H12, MCPIP; ribonuclease ZC3H12 [EC:3.1.-.-]
K23175 RNU2; ribonuclease U2 [EC:4.6.1.20]
K08300 rne; ribonuclease E [EC:3.1.26.12]
K08301 rng, cafA; ribonuclease G [EC:3.1.26.-]
K03685 rnc, DROSHA, RNT1; ribonuclease III [EC:3.1.26.3]
K12574 rnj; ribonuclease J [EC:3.1.-.-]
K18682 rny; ribonucrease Y [EC:3.1.-.-]
K12573 rnr, vacB; ribonuclease R [EC:3.1.13.1]
K01167 rnaSA; ribonuclease T1 [EC:4.6.1.24]
K13288 orn, REX2, REXO2; oligoribonuclease [EC:3.1.-.-]
K03698 cbf, cbf1; 3'-5' exoribonuclease [EC:3.1.-.-]
K03732 rhlB; ATP-dependent RNA helicase RhlB [EC:5.6.2.7]
K11927 rhlE; ATP-dependent RNA helicase RhlE [EC:5.6.2.7]
K05592 deaD, cshA; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]
K18692 cshB; ATP-dependent RNA helicase CshB [EC:5.6.2.7]
K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
K01689 ENO1_2_3, eno; enolase 1/2/3 [EC:4.2.1.11]
K00962 pnp, PNPT1; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
K03628 rho; transcription termination factor Rho
K00850 pfkA, PFK; 6-phosphofructokinase 1 [EC:2.7.1.11]
K04043 dnaK, HSPA9; molecular chaperone DnaK
K04077 groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7]
K03666 hfq; host factor-I protein
K00937 ppk1; polyphosphate kinase [EC:2.7.4.1]
K22468 ppk2; polyphosphate kinase [EC:2.7.4.34]
K00970 pcnB; poly(A) polymerase [EC:2.7.7.19]
K08311 nudH; putative (di)nucleoside polyphosphate hydrolase [EC:3.6.1.-]
K03563 csrA; carbon storage regulator
K18765 csrD; RNase E specificity factor CsrD
K02553 rraA, menG; regulator of ribonuclease activity A
K09893 rraB; regulator of ribonuclease activity B
K06958 rapZ; RNase adapter protein RapZ
K03727 helY; ATP-dependent RNA helicase HelY [EC:5.6.2.6]
K03578 hrpA; ATP-dependent RNA helicase HrpA [EC:5.6.2.6]
K03579 hrpB; ATP-dependent RNA helicase HrpB [EC:5.6.2.6]
K18502 dsrA; small regulatory RNA DsrA
K18503 chiX, sroB; small regulatory RNA ChiX
K18504 arcZ; small regulatory RNA ArcZ
K15841 glmY; small regulatory RNA GlmY
K18505 glmZ; small regulatory RNA GlmZ
K18506 sgrS; small regulatory RNA SgrS
K18507 ryhB; small regulatory RNA RyhB
K18508 rybB; small regulatory RNA RybB
K18509 rydC; small regulatory RNA RydC
K18510 fnrS; small regulatory RNA FnrS
K18511 micA; small regulatory RNA MicA
K18512 micC; small regulatory RNA MicC
K18513 micF; small regulatory RNA MicF
K18514 mgrR; small regulatory RNA MgrR
K18515 csrB; small regulatory RNA CsrB
K18516 csrC; small regulatory RNA CsrC
K18517 dicF; small regulatory RNA DicF
K18518 rprA; small regulatory RNA RprA
K18519 rseX; small regulatory RNA RseX
K18520 cyaR, ryeE; small regulatory RNA CyaR
K18521 gcvB; small regulatory RNA GcvB
K18522 omrA, rygA; small regulatory RNA OmrA
K18523 omrB, rygB; small regulatory RNA OmrB
K18525 gadY; small regulatory RNA GadY
K18526 istR; sRNA antisense regulator of TisB protein
K18527 spf; small regulatory RNA Spot 42
K18528 oxyS; small regulatory RNA OxyS
K03725 K03725; putative ATP-dependent RNA helicase [EC:5.6.2.-]
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03041 Spliceosome [BR:ko03041]
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03011 Ribosome [BR:ko03011]
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03009 Ribosome biogenesis [BR:ko03009]
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03016 Transfer RNA biogenesis [BR:ko03016]
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03012 Translation factors [BR:ko03012]
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03110 Chaperones and folding catalysts [BR:ko03110]
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04131 Membrane trafficking [BR:ko04131]
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04121 Ubiquitin system [BR:ko04121]
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03051 Proteasome [BR:ko03051]
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03032 DNA replication proteins [BR:ko03032]
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03036 Chromosome and associated proteins [BR:ko03036]
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03400 DNA repair and recombination proteins [BR:ko03400]
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03029 Mitochondrial biogenesis [BR:ko03029]
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09183 Protein families: signaling and cellular processes
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02000 Transporters [BR:ko02000]
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02044 Secretion system [BR:ko02044]
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02042 Bacterial toxins [BR:ko02042]
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02022 Two-component system [BR:ko02022]
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02035 Bacterial motility proteins [BR:ko02035]
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03037 Cilium and associated proteins [BR:ko03037]
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04812 Cytoskeleton proteins [BR:ko04812]
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04147 Exosome [BR:ko04147]
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02048 Prokaryotic defense system [BR:ko02048]
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04030 G protein-coupled receptors [BR:ko04030]
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04050 Cytokine receptors [BR:ko04050]
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04054 Pattern recognition receptors [BR:ko04054]
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03310 Nuclear receptors [BR:ko03310]
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04040 Ion channels [BR:ko04040]
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04031 GTP-binding proteins [BR:ko04031]
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04052 Cytokines and neuropeptides [BR:ko04052]
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K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
K05481 IL1RN, IL1F3; interleukin 1 receptor antagonist
K05488 IL1F10, FKSG75; interleukin 1 family member 10
K05429 IL2; interleukin 2
K04736 IL3; interleukin 3
K05430 IL4; interleukin 4
K05428 IL5; interleukin 5
K05405 IL6; interleukin 6
K05431 IL7; interleukin 7
K05432 IL9; interleukin 9
K05443 IL10, CSIF; interleukin 10
K05417 IL11; interleukin 11
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05435 IL13; interleukin 13
K05433 IL15; interleukin 15
K22628 IL16; interleukin 16
K05489 IL17A, CTLA8; interleukin 17A
K05490 IL17B, CX1; interleukin 17B
K05491 IL17C, CX2; interleukin 17C
K05492 IL17D, IL27; interleukin 17D
K05493 IL17E, IL25; interleukin 17E
K05494 IL17F, ML1; interleukin 17F
K05482 IL18, IL1F4; interleukin 18
K05444 IL19; interleukin 19
K22667 IL20; interleukin 20
K05434 IL21; interleukin 21
K05445 IL22, IL-TIF; interleukin 22
K05426 IL23A; interleukin 23 subunit alpha
K22668 IL24; interleukin 24
K05446 IL26; interleukin 26
K22629 IL27, IL27A; interleukin 27 subunit alpha
K24476 EBI3, IL27B; interleukin 27 subunit beta
K22631 IL31; interleukin 31
K22632 IL32; interleukin 32
K12967 IL33; interleukin 33
K22633 IL34; interleukin 34
K05484 IL36A, IL1F6; interleukin 36 alpha
K05486 IL36B, IL1F8; interleukin 36 beta
K05487 IL36G, IL1F9; interleukin 36 gamma
K05483 IL36RN, IL1F5; interleukin 36 receptor antagonist protein
K05485 IL37, IL1F7; interleukin 37
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K04687 IFNG; interferon gamma
K05442 IFNE; interferon epsilon
K05441 IFNK; interferon kappa
K05447 IFNL1, IL29; interferon lambda 1
K22669 IFNL2_3, IL28; interferon lambda 2/3
K05440 IFNW; interferon omega
K27353 IFNT; interferon tau
K05453 CSF1, MCSF; macrophage colony-stimulating factor 1
K05427 CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
K05423 CSF3, GCSF; granulocyte colony-stimulating factor
K05437 EPO; erythropoietin
K05438 GH; growth hormone
K06854 THPO; thrombopoietin
K05436 TSLP; thymic stromal lymphopoietin
K05418 OSM; oncostatin M
K05419 LIF; leukemia inhibitory factor
K05420 CNTF; ciliary neurotrophic factor
K05421 CLCF1, BSF3, CLC; cardiotrophin-like cytokine factor 1
K05422 CTF1, CT1; cardiotrophin 1
K24382 CTF2; cardiotrophin 2
K05514 CCL1; C-C motif chemokine 1
K14624 CCL2, MCP1; C-C motif chemokine 2
K05408 CCL3; C-C motif chemokine 3
K12964 CCL4; C-C motif chemokine 4
K12499 CCL5; C-C motif chemokine 5
K05510 CCL6; C-C motif chemokine 6
K05509 CCL7; C-C motif chemokine 7
K16596 CCL8; C-C motif chemokine 8
K22671 CCL9; C-C motif chemokine 9
K16597 CCL11; C-C motif chemokine 11
K16595 CCL13; C-C motif chemokine 13
K21092 CCL14; C-C motif chemokine 14
K05511 CCL15_23; C-C motif chemokine 15/23
K21093 CCL16; C-C motif chemokine 16
K21083 CCL17; C-C motif chemokine 17
K21094 CCL18; C-C motif chemokine 18
K05512 CCL19, ELC; C-C motif chemokine 19
K14625 CCL20; C-C motif chemokine 20
K16062 CCL21, SLC; C-C motif chemokine 21
K21095 CCL22; C-C motif chemokine 22
K21097 CCL24; C-C motif chemokine 24
K13072 CCL25; C-C motif chemokine 25
K21096 CCL26; C-C motif chemokine 26
K16598 CCL27; C-C motif chemokine 27
K05513 CCL28; C-C motif chemokine 28
K05505 CXCL1_2_3, GRO; C-X-C motif chemokine 1/2/3
K05407 PF4, CXCL4; platelet factor 4
K05506 CXCL5_6, SCYB5_6; C-X-C motif chemokine 5/6
K10029 PPBP, CXCL7; platelet basic protein
K10030 IL8, CXCL8; interleukin 8
K05416 CXCL9; C-X-C motif chemokine 9
K12671 CXCL10, IP10; C-X-C motif chemokine 10
K12672 CXCL11, I-TAC; C-X-C motif chemokine 11
K10031 CXCL12; C-X-C motif chemokine 12
K10032 CXCL13; C-X-C motif chemokine 13
K10033 CXCL14, SCYB14; C-X-C motif chemokine 14
K10034 CXCL15; C-X-C motif chemokine 15
K10035 CXCL16; C-X-C motif chemokine 16
K22627 CXCL17; C-X-C motif chemokine 17
K05508 CX3CL1, NTT; C-X3-C motif chemokine 1
K05507 XCL1, SCM1; C motif chemokine 1
K22675 XCL2, SCM1B; C motif chemokine 2
K24191 PROK; prokineticin
K25387 GPR15L; protein GPR15L
K25418 CYTL1; cytokine-like protein 1
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K05468 LTA, TNFB; lymphotoxin alpha (TNF superfamily, member 1)
K03157 LTB, TNFC; lymphotoxin beta (TNF superfamily, member 3)
K05469 TNFSF4, OX40L, CD252; tumor necrosis factor ligand superfamily member 4
K03161 TNFSF5, CD40L, CD154; tumor necrosis factor ligand superfamily member 5
K04389 TNFSF6, FASL, CD178; tumor necrosis factor ligand superfamily member 6
K05470 TNFSF7, CD70; tumor necrosis factor ligand superfamily member 7
K05471 TNFSF8, CD153; tumor necrosis factor ligand superfamily member 8
K05472 TNFSF9, CD137L; tumor necrosis factor ligand superfamily member 9
K04721 TNFSF10, TRAIL, CD253; tumor necrosis factor ligand superfamily member 10
K05473 TNFSF11, RANKL, CD254; tumor necrosis factor ligand superfamily member 11
K05474 TNFSF12, TWEAK; tumor necrosis factor ligand superfamily member 12
K05475 TNFSF13, APRIL, CD256; tumor necrosis factor ligand superfamily member 13
K05476 TNFSF13B, TNFSF20, CD257; tumor necrosis factor ligand superfamily member 13B
K05477 TNFSF14, LIGHT, CD258; tumor necrosis factor ligand superfamily member 14
K05478 TNFSF15, VEGI; tumor necrosis factor ligand superfamily member 15
K05479 TNFSF18, GITRL; tumor necrosis factor ligand superfamily member 18
K05480 EDA; ectodysplasin-A
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04384 TGFBN; transforming growth factor beta, invertebrate
K05502 BMP1, TLD; bone morphogenetic protein 1 [EC:3.4.24.19]
K21283 BMP2; bone morphogenetic protein 2
K05496 BMP3; bone morphogenetic protein 3
K04662 BMP4; bone morphogenetic protein 4
K04663 BMP5; bone morphogenetic protein 5
K16620 BMP6; bone morphogenetic protein 6
K16621 BMP7; bone morphogenetic protein 7
K16622 BMP8; bone morphogenetic protein 8
K22670 BMP10; bone morphogenetic protein 10
K05498 BMP15, GDF9B; bone morphogenetic protein 15
K05495 GDF1; growth differentiation factor 1
K05503 GDF2, BMP9; growth differentiation factor 2
K22672 GDF3; growth differentiation factor 3
K04664 GDF5; growth differentiation factor 5
K20012 GDF6; growth differentiation factor 6
K20013 GDF7; growth differentiation factor 7
K05497 MSTN, GDF8; growth differentiation factor 8
K22673 GDF9; growth differentiation factor 9
K22674 GDF10, BMP3B; growth differentiation factor 10
K22679 GDF11; growth differentiation factor 11
K05504 GDF15; growth differentiation factor 15
K04666 NODAL; nodal
K05500 INHA; inhibin, alpha
K04667 INHBA; inhibin beta A chain
K22687 INHBB; inhibin beta B chain
K22688 INHBC; inhibin beta C chain
K22689 INHBE; inhibin beta E chain
K04665 AMH; anti-mullerian hormone
K04668 LEFTY; left-right determination factor
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K05450 PDGFC_D; platelet derived growth factor C/D
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K05449 VEGFC_D; vascular endothelial growth factor C/D
K16859 PGF; placenta growth factor
K05451 NGFA; nerve growth factor, alpha
K02582 NGFB; nerve growth factor, beta
K04356 NTF3; neurotrophin 3
K12457 NTF4; neurotrophin 4
K04355 BDNF; brain-derived neurotrophic factor
K05452 GDNF; glial cell derived neurotrophic factor
K25414 NRTN; neurturin
K25415 ARTN; artemin
K25416 PSPN; persephin
K05454 FLT3LG; fms-related tyrosine kinase 3 ligand
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K22413 FGF11_12_13, FHF3_1_2; fibroblast growth factor 11/12/13
K23920 FGF14, FHF4; fibroblast growth factor 14
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K05455 NRG1; neuregulin 1
K05456 NRG2; neuregulin 2
K05457 NRG3; neuregulin 3
K05458 NRG4; neuregulin 4
K05459 IGF1; insulin-like growth factor 1
K13769 IGF2; insulin-like growth factor 2
K05460 HGF; hepatocyte growth factor
K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K09784 EREG; epiregulin
K09782 AREG; amphiregulin
K05461 KITLG; KIT ligand
K05462 EFNA; ephrin-A
K05463 EFNB; ephrin-B
K05464 GAS6; growth arrest-specific 6
K05465 ANGPT1; angiopoietin 1
K05466 ANGPT2; angiopoietin 2
K05467 ANGPT4; angiopoietin 4
K09821 AGT, SERPINA8; angiotensinogen
K03898 KNG, BK; kininogen
K05235 NTS; neurotensin
K05225 APLN; apelin
K05223 NMB; neuromedin B
K05224 GRP; gastrin-releasing peptide
K05226 CCK; cholecystokinin
K16366 EDN1; endothelin-1
K16367 EDN2; endothelin-2
K05227 EDN3; endothelin-3
K05244 GAL; galanin
K25482 GALP; galanin-like peptide
K25694 SPX; spexin
K05254 GHRL; ghrelin
K05265 MLN; motilin
K05249 NMU; neuromedin U
K25690 NMS; neuromedin S
K05247 NPFF; neuropeptide FF-amide peptide
K25692 NPVF; pro-FMRFamide-related neuropeptide VF
K25691 NPS; neuropeptide S
K05232 NPY; neuropeptide Y
K05234 PPY; pancreatic polypeptide
K05233 PYY; peptide YY
K05267 NPB; preproneuropeptide B
K23141 NPW; neuropeptide W
K05228 POMC; proopiomelanocortin
K18832 PENK; proenkephalin A
K15840 PDYN, PENKB; proenkephalin B (prodynorphin)
K25696 PNOC; prepronociceptin
K25693 QRFP; orexigenic neuropeptide QRFP
K05243 OXT; oxytocin-neurophysin 1
K05237 SST; somatostatin
K05238 CORT; cortistatin
K05239 TAC1; tachykinin 1
K05240 TAC3; tachykinin 3
K05241 TAC4; tachykinin 4
K05248 UTS2; urotensin 2
K24267 UTS2B; urotensin-2B
K05242 AVP; arginine vasopressin
K05269 PRH; Prolactin-releasing peptide
K23140 KISS1; metastasis-suppressor KiSS-1
K05246 HCRT; hypocretin (orexin) neuropeptide
K25695 VGF; neurosecretory protein VGF
K19990 CHGA; chromogranin-A
K19991 CHGB; chromogranin-B
K25732 SCG2; secretogranin-2
K25733 SCG3; secretogranin-3
K25734 SCG5; neuroendocrine protein 7B2
K05252 GNRH; gonadotropin-releasing hormone
K05253 TRH; thyrotropin-releasing hormone
K21998 RLN1_2; relaxin 1/2
K22000 RLN3; relaxin 3
K21999 INSL3; insulin-like 3
K22001 INSL5; insulin-like 5
K05229 PMCH; pro-melanin-concentrating hormone
K13768 GAST; gastrin
K12332 CALC; calcitonin
K12333 ADM; adrenomedullin
K25343 ADM2; adrenomedullin-2
K08039 IAPP; islet amyloid polypeptide
K05256 CRH; corticotropin-releasing hormone
K23142 UCN; urcortin
K05257 UCN2_3; urocortin 2/3
K05258 GIP; gastric inhibitory polypeptide
K05259 GCG; glucagon
K05260 GHRH; growth hormone-releasing hormone
K05261 PTH; parathyroid hormone
K23143 PTH2, TIP39; tuberoinfundibular peptide of 39 residues
K05262 ADCYAP; pituitary adenylate cyclase-activating polypeptide
K05263 SCT; secretin
K05264 VIP; vasoactive intestinal peptide
K22608 PTHLH, PTHRP; parathyroid hormone-related hormone
K08522 CGA; glycoprotein hormones alpha chain
K05250 FSHB; follitropin subunit beta
K08521 LHB; lutropin subunit beta
K10045 CGB; chorionic gonadotropin, beta polypeptide
K05251 TSHB; thyrotropin subunit beta
K25483 GPHA2; glycoprotein hormone alpha-2
K25484 GPHB5; glycoprotein hormone beta-5
K12334 NPPA; natriuretic peptide A
K12335 NPPB; natriuretic peptide B
K12336 NPPC; natriuretic peptide C
K16656 NXPH1; neurexophilin-1
K16657 NXPH2; neurexophilin-2
K16658 NXPH3; neurexophilin-3
K25711 NXPH4; neurexophilin-4
K04526 INS; insulin
K05424 LEP; leptin
K05439 PRL; prolactin
K25453 CARTPT; cocaine- and amphetamine-regulated transcript protein
K05231 AGRP; agouti related protein
K08762 DBI, ACBP; diazepam-binding inhibitor (GABA receptor modulator, acyl-CoA-binding protein)
K24235 CBLN; cerebellin
K07296 ADIPOQ, ACDC; adiponectin
K03462 NAMPT; nicotinamide phosphoribosyltransferase [EC:2.4.2.12]
K13438 RETN; resistin
K20371 NUCB; nucleobindin
K13113 UBL5, HUB1; ubiquitin-like protein 5
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04515 Cell adhesion molecules [BR:ko04515]
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04090 CD molecules [BR:ko04090]
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01504 Antimicrobial resistance genes [BR:ko01504]
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00535 Proteoglycans [BR:ko00535]
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00536 Glycosaminoglycan binding proteins [BR:ko00536]
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K04519 IL1B; interleukin 1 beta
K05429 IL2; interleukin 2
K04736 IL3; interleukin 3
K05430 IL4; interleukin 4
K05428 IL5; interleukin 5
K05431 IL7; interleukin 7
K05443 IL10, CSIF; interleukin 10
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05427 CSF2, GMCSF; granulocyte-macrophage colony-stimulating factor
K04687 IFNG; interferon gamma
K03156 TNF, TNFA; tumor necrosis factor superfamily, member 2
K14624 CCL2, MCP1; C-C motif chemokine 2
K05408 CCL3; C-C motif chemokine 3
K12499 CCL5; C-C motif chemokine 5
K16595 CCL13; C-C motif chemokine 13
K05407 PF4, CXCL4; platelet factor 4
K10030 IL8, CXCL8; interleukin 8
K12671 CXCL10, IP10; C-X-C motif chemokine 10
K10031 CXCL12; C-X-C motif chemokine 12
K06495 SELL, CD62L; selectin, lymphocyte
K06496 SELP, CD62P; selectin, platelet
K06461 ITGAM, CD11b; integrin alpha M
K06491 NCAM, CD56; neural cell adhesion molecule
K06471 PECAM1, CD31; platelet/endothelial cell adhesion molecule
K21283 BMP2; bone morphogenetic protein 2
K04662 BMP4; bone morphogenetic protein 4
K16621 BMP7; bone morphogenetic protein 7
K06224 HH; hedgehog
K11988 SHH; sonic hedgehog
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K09782 AREG; amphiregulin
K09783 BTC; betacellulin
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K22413 FGF11_12_13, FHF3_1_2; fibroblast growth factor 11/12/13
K23920 FGF14, FHF4; fibroblast growth factor 14
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K04362 FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2, CD332; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K08523 HBEGF; heparin-binding EGF-like growth factor
K05460 HGF; hepatocyte growth factor
K06828 MDK; midkine
K13769 IGF2; insulin-like growth factor 2
K05455 NRG1; neuregulin 1
K16641 HDGF; hepatoma-derived growth factor
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K16642 PTN; pleiotrophin
K05448 VEGFA; vascular endothelial growth factor A
K25640 MPIG6B; megakaryocyte and platelet inhibitory receptor G6b
K03903 FGA; fibrinogen alpha chain
K03904 FGB; fibrinogen beta chain
K03905 FGG; fibrinogen gamma chain
K05717 FN1; fibronectin 1
K06825 FBN1; fibrillin 1
K23342 FBN2_3; fibrillin 2/3
K06252 TN; tenascin
K24354 SMOC; SPARC-related modular calcium-binding protein
K16857 THBS1; thrombospondin 1
K04659 THBS2S; thrombospondin 2/3/4/5
K06251 VTN; vitronectin
K06236 COL1A; collagen type I alpha
K19719 COL2A; collagen type II alpha
K19720 COL3A; collagen type III alpha
K06237 COL4A; collagen type IV alpha
K19721 COL5AS; collagen type V/XI/XXIV/XXVII, alpha
K06238 COL6A; collagen type VI alpha
K16617 COL13A; collagen type XIII alpha
K06823 COL18A; collagen type XVIII alpha
K24340 COL19A; collagen type XIX alpha
K24355 COL23A; collagen type XXIII alpha
K24356 COL25A; collagen type XXV alpha
K26586 COLQ; acetylcholinesterase collagenic tail peptide
K05462 EFNA; ephrin-A
K06843 NTN1; netrin 1
K06838 SLIT1; slit 1
K06839 SLIT2; slit 2
K06850 SLIT3; slit 3
K01313 F2; coagulation factor II (thrombin) [EC:3.4.21.5]
K01314 F10; coagulation factor X [EC:3.4.21.6]
K03913 SERPINA5, PCI; protein C inhibitor
K03911 SERPINC1, AT3; antithrombin III
K03912 SERPIND1, HCF2; heparin cofactor II
K03982 SERPINE1, PAI1; plasminogen activator inhibitor 1
K16643 SERPINE2; glia-derived nexin
K01343 PLAT; tissue plasminogen activator [EC:3.4.21.68]
K01348 PLAU; urokinase plasminogen activator [EC:3.4.21.73]
K03909 TFPI; tissue factor pathway inhibitor
K01327 ELANE; leukocyte elastase [EC:3.4.21.37]
K07964 HPSE; heparanase [EC:3.2.1.166]
K07965 HPSE2; heparanase 2 [EC:3.2.1.-]
K01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35]
K01059 LPL; lipoprotein lipase [EC:3.1.1.34]
K16627 SOD3; superoxide dismutase, Cu-Zn family [EC:1.15.1.1]
K19252 VP1; Dependoparvovirus capsid protein VP1/VP2/VP3
K19255 gB; Herpesviridae envelope glycoprotein B
K19256 gC; Simplexvirus envelope glycoprotein C
K19264 gD; Simplexvirus envelope glycoprotein D
K19257 gM, UL10; Herpesviridae envelope glycoprotein M
K22773 gB, UL55; Betaherpesvirinae envelope glycoprotein B
K19287 env, gp160; HIV envelope glycoprotein gp160
K24266 gp120; HIV envelope glycoprotein gp120
K19258 tat; HIV protein Tat
K19259 env; Deltaretrovirus envelope glycoprotein gp62
K24862 gp46; HTLV envelope surface glycoprotein gp46
K19288 p130; Alphavirus structral polyprotein
K19260 L1; Papillomaviridae major capsid protein L1
K19261 F; Pneumoviridae fusion glycoprotein F0
K19262 L5; Mastadenovirus fiber protein
K19263 A27L; Orthopoxvirus protein A27
K13836 CSP; circumsporozoite protein
K15125 fhaB; filamentous hemagglutinin
K16644 actA; actin-assembly inducing protein
K16645 hbhA; heparin binding hemagglutinin HbhA
K16631 ANG, RNASE5; angiogenin [EC:3.1.27.-]
K16646 ANXA5; annexin A5
K09025 APOA5; apolipoprotein A-V
K14462 APOB; apolipoprotein B
K04524 APOE; apolipoprotein E
K04520 APP; amyloid beta A4 protein
K01363 CTSB; cathepsin B [EC:3.4.22.1]
K01319 CTSG; cathepsin G [EC:3.4.21.20]
K05634 PRNP, PrP, CD230; prion protein
K05849 SLC8A, NCX; solute carrier family 8 (sodium/calcium exchanger)
K01242 CD38; ADP-ribosyl cyclase 1 [EC:3.2.2.6 2.4.99.20]
K06256 CD44; CD44 antigen
K06267 HMMR, RHAMM, CD168; hyaluronan-mediated motility receptor
K06490 ICAM1, CD54; intercellular adhesion molecule 1
K10159 TLR2, CD282; toll-like receptor 2
K10160 TLR4, CD284; toll-like receptor 4
K10077 LAYN; layilin
K19012 LYVE1; lymphatic vessel endothelial hyaluronan receptor 1
K19020 STAB1; stabilin-1
K19013 STAB2, HARE; stabilin-2
K19031 CEMIP, KIAA1199; cell migration-inducing and hyaluronan-binding protein [EC:3.2.1.35]
K22144 TEME2; cell surface hyaluronidase [EC:3.2.1.35]
K06792 AGC1, CSPG1; aggrecan 1
K06795 BCAN; brevican
K15414 C1QBP; complement component 1 Q subcomponent-binding protein, mitochondrial
K08648 HABP2; hyaluronan binding protein 2 [EC:3.4.21.-]
K06848 HAPLN1, CRTL1; hyaluronan and proteoglycan link protein 1
K06851 HAPLN2; hyaluronan and proteoglycan link protein 2
K06853 HAPLN4; hyaluronan and proteoglycan link protein 4
K18977 HPX; hemopexin
K19014 ITIH1, SHAP; inter-alpha-trypsin inhibitor heavy chain H1
K19015 ITIH2, SHAP; inter-alpha-trypsin inhibitor heavy chain H2
K24513 ITIH3, SHAP; inter-alpha-trypsin inhibitor heavy chain H3
K06794 NCAN, CSPG3; neurocan core protein
K19016 IMPG1, SPACR; interphotoreceptor matrix proteoglycan 1
K19017 IMPG2, SPACRCAN; interphotoreceptor matrix proteoglycan 2
K19018 TNFAIP6, TSG6; tumor necrosis factor-inducible gene 6 protein
K06793 VCAN, CSPG2; versican core protein
K09554 CDC37; cell division cycle protein 37
K19019 HABP4; intracellular hyaluronan-binding protein 4
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00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:ko00537]
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04091 Lectins [BR:ko04091]
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04990 Domain-containing proteins not elsewhere classified [BR:ko04990]
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09185 Viral protein families
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09184 RNA family
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09190 Not Included in Pathway or Brite
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KEGG Orthology (KO)