KEGG image  Drug Metabolizing Enzymes and Transporters

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[ Enzymes | Transporters ]

Drug metabolizing enzymes

Drug KEGG Substrate Inhibitor Inducer
Abametapir (USAN/INN) D10687 CYP1A2
Abemaciclib (JAN/USAN/INN) D10688 CYP3A
Abiraterone acetate (JAN/USP) D09701 CYP3A4
Abrocitinib (JAN/USAN) D11400 CYP2C19, CYP2C9
Acalabrutinib (JAN/USAN/INN) D10893 CYP3A
Acalabrutinib maleate (USAN) D11720 CYP3A
Acalabrutinib maleate hydrate (JAN) D12704 CYP3A
Acetone (NF) D02311 CYP2E1
Acetylcholine chloride (JP18/USP/INN) D00999 ACHE
Acetylsalicylic acid and lansoprazole D10527 CYP2C19, CYP3A4
Aclidinium bromide (JAN/USAN/INN) D08837 BCHE CYP2D6, CYP3A4, CYP3A5
Aclidinium bromide and formoterol fumarate D11857 UGT
Adagrasib (USAN/INN) D12301 CYP3A4
Ajmaline (JP18) D00199 CYP2D6
Albuterol and budesonide D12757 SULT1A3
Alectinib (USAN/INN) D10542 CYP3A4
Alectinib hydrochloride (JAN) D10450 CYP3A4
Alfuzosin (INN) D07124 CYP3A4
Alfuzosin hydrochloride (JAN/USAN) D01692 CYP3A4
Aliskiren (USAN/INN) D03208 CYP3A4
Aliskiren fumarate (JAN/USAN) D06412 CYP3A4
Allopurinol (JP18/USP/INN) D00224 CYP1A2
Allopurinol sodium D07564 CYP1A2
Almotriptan (USAN) D02824 MAOA, CYP3A4, CYP2D6; FMO3
Almotriptan malate (USP) D02825 MAOA, CYP3A4, CYP2D6; FMO3
Alosetron (INN) D07129 CYP1A2; CYP3A4, CYP2C9
Alosetron hydrochloride (USAN) D02829 CYP1A2; CYP3A4, CYP2C9
Alprazolam (JP18/USP/INN) D00225 CYP3A
Alprenolol (INN) D07156 CYP2D6
Alprenolol hydrochloride (JP18/USAN) D01182 CYP2D6
Amenamevir (JAN/INN) D10564 CYP3A CYP3A, CYP2B6
Amfetamine (INN) D07445 CYP2D6
Aminophylline (USP/INN) D00227 CYP1A2
Aminophylline dihydrate D11630 CYP1A2
Aminophylline hydrate (JP18) D05429 CYP1A2
Amiodarone (USAN/INN) D02910 CYP3A4
Amiodarone hydrochloride (JP18/USP) D00636 CYP3A4
Amitriptyline (INN) D07448 CYP2D6; CYP1A2, CYP3A4, CYP2C19
Amitriptyline hydrochloride (JP18/USP) D00809 CYP2D6; CYP1A2, CYP3A4, CYP2C19
Amlodipine (USP/INN) D07450 CYP3A4
Amlodipine benzoate D11881 CYP3A4
Amlodipine besilate and atorvastatin calcium D08488 CYP3A4
Amlodipine besylate (USP) D00615 CYP3A4
Amlodipine maleate (USAN) D02914 CYP3A4
Amobarbital (JP18/INN) D00555 CYP3A
Amobarbital sodium (JAN/USP) D02252 CYP3A
Amodiaquine (USP/INN) D02922 CYP2C8
Amodiaquine hydrochloride (USP) D02466 CYP2C8
Amoxapine (JP18/USP/INN) D00228 CYP2D6
Amoxicillin hydrate, clarithromycin and lansoprazole D08774 CYP2C19, CYP3A4 CYP3A4
Amphetamine sulfate (USP) D02074 CYP2D6
Ampiroxicam (JP18/INN) D01397 CYP2C9
Amprenavir (JAN/USAN/INN) D00894 CYP3A4 CYP3A CYP3A
Anagrelide (INN/BAN) D07455 CYP1A1, CYP1A2
Anagrelide hydrochloride (USP) D02933 CYP1A1, CYP1A2
Anagrelide hydrochloride hydrate (JAN) D10255 CYP1A1, CYP1A2
Anamorelin hydrochloride (JAN/USAN) D08856 CYP3A4
Anastrozole (JP18/USP/INN) D00960 CYP1A2, CYP2C9, CYP3A4
Apalutamide (JAN/INN) D11040 CYP2C8, CYP3A4 CYP3A4, CYP2C19; CYP2C9
Apixaban (JAN/USAN/INN) D03213 CYP3A4, CYP3A5
Aprepitant (JAN/USP/INN) D02968 CYP3A4 CYP3A4 CYP3A4, CYP2C9
Aprindine (USAN/INN) D02969 CYP2D6
Aprindine hydrochloride (JP18/USAN) D01326 CYP2D6
Aranidipine (JAN/INN) D01562 CYP3A4
Argatroban (USP) D00181 CYP3A4
Aripiprazole (JAN/USP/INN) D01164 CYP3A4, CYP2D6
Aripiprazole cavoxil (USAN) D10355 CYP3A4, CYP2D6
Aripiprazole hydrate (JAN) D10516 CYP3A4, CYP2D6
Aripiprazole lauroxil (USAN) D10364 CYP3A4, CYP2D6
Armodafinil (USAN/INN) D03215 CYP3A4, CYP3A5
Artemether and lumefantrine D02484 CYP3A
Asciminib (USAN/INN) D11403 CYP3A4, UGT2B7, UGT2B17
Asciminib hydrochloride (JAN/USAN) D11404 CYP3A4, UGT2B7, UGT2B17
Asenapine (INN) D11769 CYP1A2 CYP2D6
Asenapine maleate (JAN/USAN) D02995 CYP1A2 CYP2D6
Aspirin and omeprazole D11616 CYP2C19; CYP3A4
Astemizole (JAN/USP/INN) D00234 CYP3A
Asunaprevir (JAN/USAN) D10093 CYP3A CYP2D6 CYP3A4
Atazanavir (INN) D07471 CYP3A4, UGT1A1
Atazanavir and cobicistat D10753 CYP3A4 CYP3A, CYP2D6; CYP2C8, UGT1A1
Atazanavir sulfate (JAN/USAN) D01276 CYP3A4, UGT1A1
Atenolol (JP18/USP/INN) D00235 CYP2D6
Atogepant (USAN) D11313 CYP3A4
Atomoxetine (USP/INN) D07473 CYP2D6
Atomoxetine hydrochloride (JAN/USP) D02574 CYP2D6
Atorvastatin (INN) D07474 CYP3A4
Atorvastatin calcium (USP) D02258 CYP3A4
Atorvastatin calcium anhydorous D00887 CYP3A4
Atorvastatin calcium propylene glycol solvate D11095 CYP3A4
Atovaquone and proguanil hydrochloride D02472 CYP2C19
Avacopan (JAN/USAN/INN) D11093 CYP3A4
Avanafil (USAN/INN) D03217 CYP3A4
Avatrombopag (USAN/INN) D10306 CYP3A4, CYP2C9
Avatrombopag maleate (JAN/USAN) D10307 CYP3A4, CYP2C9
Axitinib (JAN/USAN) D03218 CYP3A4, CYP3A5
Azelastine hydrochloride and fluticasone propionate D11656 CYP3A4
Azelnidipine (JP18/INN) D01145 CYP3A4
Azilsartan (JAN/USAN/INN) D08864 CYP2C9
Azilsartan and amlodipine besilate D10524 CYP3A4
Barnidipine (INN) D07494 CYP3A4
Barnidipine hydrochloride (JAN) D01104 CYP3A4
Beclomethasone dipropionate (USP) D00689 CYP3A4
Beclomethasone dipropionate monohydrate D11572 CYP3A4
Bedaquiline (USAN/INN) D09872 CYP3A4
Bedaquiline fumarate (JAN/USAN) D09873 CYP3A4
Belinostat (USAN/INN) D08870 UGT1A1; CYP2A6, CYP2C9, CYP3A4
Belzutifan (JAN/USAN/INN) D11954 UGT2B17, CYP2C19; CYP3A4
Benazepril (INN) D07499 UGT
Benazepril hydrochloride (JAN/USP) D00620 UGT
Benidipine (INN) D07509 CYP3A4
Benidipine hydrochloride (JP18) D02045 CYP3A4
Benzbromarone (JP18/USAN/INN) D01056 CYP2C9 CYP2C9
Benzhydrocodone (USAN/INN) D10612 CYP2D6, CYP3A4
Benzhydrocodone and acetaminophen D11628 CYP2D6, CYP3A4
Benzhydrocodone hydrochloride (USAN) D10692 CYP2D6, CYP3A4
Bepridil (INN) D07520 CYP2D6, CYP2C9, CYP3A4 CYP2D6
Bepridil hydrochloride (USAN) D00631 CYP2D6, CYP2C9, CYP3A4 CYP2D6
Berotralstat (USAN/INN) D11673 CYP2D6, CYP3A4
Berotralstat hydrochloride (JAN/USAN) D11674 CYP2D6, CYP3A4
Berythromycin (USAN/INN) D03098 CYP3A CYP3A
Betamethasone acetate and betamethasone sodium phosphate D04446 CYP3A4
Betamethasone and d-chlorpheniramine maleate D04447 CYP3A4
Bexagliflozin (USAN) D10865 UGT1A9; CYP3A
Bexarotene (JAN/USAN/INN) D03106 CYP3A
Bicalutamide (JP18/USP/INN) D00961 CYP3A4
Blonanserin (JAN/INN) D01176 CYP3A4
Boceprevir (INN/USAN) D08876 CYP3A
Bopindolol (INN) D07537 CYP2D6
Bopindolol malonate (JAN) D01794 CYP2D6
Bosentan (INN) D07538 CYP2C9, CYP3A4 CYP2C9, CYP3A4
Bosentan (USAN) D01227 CYP2C9, CYP3A4 CYP2C9, CYP3A4
Bosutinib (USAN) D03252 CYP3A4
Bosutinib hydrate (JAN) D09728 CYP3A4
Brexpiprazole (JAN/USAN/INN) D10309 CYP3A4, CYP2D6
Brigatinib (JAN/USAN) D10866 CYP3A4
Brincidofovir (USAN) D10547 CYP4F2
Brinzolamide and timolol maleate D10512 CYP3A4, CYP2D6; CYP2A6, CYP2B6, CYP2C8, CYP2C9
Brivaracetam (JAN/USAN/INN) D08879 CYP2C19
Bromocriptine (USAN/INN) D03165 CYP3A4 CYP3A4
Bromocriptine mesylate (USP) D00780 CYP3A4 CYP3A4
Bromperidol (JAN/USAN/INN) D01101 CYP3A4
Bromperidol decanoate (USAN) D02626 CYP3A4
Brotizolam (JP18/USAN/INN) D01744 CYP3A4
Budesonide (JP18/USP/INN) D00246 CYP3A4
Budesonide and formoterol fumarate dihydrate D09595 CYP3A4, UGT
Bunitrolol hydrochloride (JAN) D01444 CYP2D6
Bupivacaine (USAN/INN) D07552 CYP3A4
Bupivacaine hydrochloride (USP) D01450 CYP3A4
Buprenorphine (JAN/INN) D07132 CYP3A4
Buprenorphine hydrochloride (JP18/USP) D00836 CYP3A4
Butalbital, acetaminophen, caffeine and codeine phosphate D11851 CYP1A2, UGT2B7, UGT2B4; CYP3A4, CYP2D6
Butalbital, aspirin, caffeine and codeine D11860 UGT2B7, UGT2B4, CYP3A4, CYP2D6
Cabazitaxel (USAN/INN) D09755 CYP3A
Cabazitaxel acetonate (JAN) D10452 CYP3A
Cabergoline (JP18/USP/INN) D00987 CYP3A4
Cabotegravir (JAN/USAN/INN) D10548 UGT1A1; UGT1A9
Cabotegravir and rilpivirine D11966 UGT1A1, CYP3A; UGT1A9
Cabotegravir sodium (JAN/USAN) D10549 UGT1A1; UGT1A9
Caffeine (USP) D00528 CYP1A2; CYP3A4, CYP2E1
Caffeine citrate (USP) D07603 CYP1A2; CYP3A4, CYP2E1
Caffeine hydrate (JP18) D01453 CYP1A2; CYP3A4, CYP2E1
Calcifediol (USP/INN) D00122 CYP27B1, CYP24A1
Canagliflozin (USAN/INN) D09592 UGT1A9, UGT2B4
Candesartan (USAN/INN) D00522 CYP2C9
Candesartan cilexetil (JP18/USP) D00626 CES, CYP2C9
Candesartan cilexetil and anmlodipine besylate (JP18) D07569 CYP3A4
Cannabidiol (USAN/INN) D10915 CYP3A4, CYP2C19, UGT1A7, UGT1A9, UGT2B7
Capecitabine (JAN/USP/INN) D01223 CYP2C9
Capivasertib (JAN/USAN) D11371 CYP3A4, UGT2B7
Capmatinib (USAN/INN) D10696 CYP3A4, AOX1
Capmatinib hydrochloride (USAN) D10891 CYP3A4, AOX1
Carbamazepine (JP18/USP/INN) D00252 CYP3A4 CYP3A4
Carbidopa, levodopa and entacapone D10293 CYP2C9, COMT
Cariprazine (USAN/INN) D09997 CYP3A4; CYP2D6
Cariprazine hydrochloride (JAN/USAN) D09876 CYP3A4; CYP2D6
Carisoprodol (JAN/USP/INN) D00768 CYP2C19
Carisoprodol and aspirin D11586 CYP2C19
Carisoprodol, aspirin and codeine phosphate D11587 CYP2C19
Carotegrast methyl (JAN) D09799 CYP3A4
Carteolol (INN) D07624 CYP2D6
Carteolol hydrochloride (JP18/USP) D00599 CYP2D6
Carvedilol (JP18/USP/INN) D00255 CYP2D6, CYP2C9, CYP3A4, CYP1A2, CYP2E1
Carvedilol phosphate (USAN) D03415 CYP2D6, CYP2C9, CYP3A4, CYP1A2, CYP2E1
Celecoxib (JP18/USP/INN) D00567 CYP2C9 CYP2D6
Cenobamate (USAN/INN) D11150 UGT2B7, CYP2E1, CYP2A6, CYP2B6; UGT2B4, CYP2C19, CYP3A4, CYP3A5
Ceritinib (JAN/USAN/INN) D10551 CYP3A
Cerivastatin (INN) D07661 CYP2C8, CYP3A4
Cerivastatin sodium (JAN/USAN) D00889 CYP2C8, CYP3A4
Cevimeline (INN) D07667 CYP2D6, CYP3A4
Cevimeline hydrochloride (USAN) D00661 CYP2D6, CYP3A4
Chlorpheniramine polistirex and codeine polistirex D12313 UGT2B7, UGT2B4, CYP3A4, CYP2D6
Chlorpromazine (USP/INN) D00270 CYP2D6 CYP2D6
Chlorpromazine hibenzate (JAN) D03274 CYP2D6 CYP2D6
Chlorpromazine hydrochloride (JP18/USP) D00789 CYP2D6 CYP2D6
Chlorpromazine hydrochloride, promethazine hydrochloride and phenobarbital D02615 CYP3A, CYP2D6
Chlorpromazine phenolphthalinate (JAN) D04034 CYP2D6 CYP2D6
Chlorpromazine tannate (JAN) D09819 CYP2D6 CYP2D6
Choline fenofibrate (USAN/INN) D08890 UGT
Ciclesonide (JAN/USAN/INN) D01703 CYP3A4
Cifenline (USAN) D03492 CYP2D6, CYP3A4
Cifenline succinate (USAN) D01455 CYP2D6, CYP3A4
Cilnidipine (JP18/INN) D01173 CYP3A4; CYP2C19
Cilostazol (JP18/USP/INN) D01896 CYP3A4; CYP2D6, CYP2C19
Cimetidine (JP18/USP/INN) D00295 CYP2D6, CYP3A4
Cimetidine hydrochloride (USP) D03503 CYP2D6, CYP3A4
Cinacalcet (USAN) D03504 CYP3A4 CYP2D6
Cinacalcet hydrochloride (JAN/USAN) D03505 CYP3A4 CYP2D6
Cinnarizine (JAN/USAN/INN) D01295 CYP2D6
Cinnarizine dihydrochloride D07734 CYP2D6
Ciprofloxacin (JP18/USP/INN) D00186 CYP1A2
Ciprofloxacin hydrate (JAN) D10822 CYP1A2
Ciprofloxacin hydrochloride (USP) D02216 CYP1A2
Ciprofloxacin lactate D07702 CYP1A2
Cisapride (JAN) D02092 CYP3A
Cisapride (USP/INN) D00274 CYP3A
Citalopram (USP/INN) D07704 CYP3A4, CYP2D6 CYP2C19
Citalopram hydrobromide (USP) D00822 CYP3A4, CYP2D6 CYP2C19
Citalopram hydrochloride D07705 CYP3A4, CYP2D6 CYP2C19
Clarithromycin (JP18/USP/INN) D00276 CYP3A4 CYP3A4
Clarithromycin lactobionate D07710 CYP3A4 CYP3A4
Clemastine (USAN) D03535 CYP2D6
Clemastine fumarate (JP18/USP) D00666 CYP2D6
Clobazam (JAN/USAN/INN) D01253 CYP3A4, CYP2C19
Clomipramine (INN) D07727 CYP2D6; CYP1A2, CYP3A4, CYP2C19
Clomipramine hydrochloride (JP18/USP) D00811 CYP2D6; CYP1A2, CYP3A4, CYP2C19
Clopidogrel (USP/INN) D07729 CYP2C19; CYP3A4, CYP1A2, CYP2B6 CYP2C8
Clopidogrel besilate D10824 CYP2C19; CYP3A4, CYP1A2, CYP2B6 CYP2C8
Clopidogrel bisulfate (USP) D00769 CYP2C19; CYP3A4, CYP1A2, CYP2B6 CYP2C8
Clopidogrel hydrochloride D10823 CYP2C19; CYP3A4, CYP1A2, CYP2B6 CYP2C8
Clopidogrel sulfate and aspirin D10513 CYP2C19; CYP1A2, CYP2B6, CYP3A4 CYP2C8
Clotrimazole (JP18/USP/INN) D00282 CYP3A4
Clozapine (JAN/USP/INN) D00283 CYP1A2, CYP3A4
Co-Trimoxazole (BAN) D00285 CYP2C8, CYP2C9
Cobicistat (JAN/USAN/INN) D09881 CYP3A; CYP2D6 CYP3A, CYP2D6
Codeine (USP) D00195 UGT2B7, UGT2B4; CYP3A4, CYP2D6
Codeine hydrochloride D07740 UGT2B7, UGT2B4; CYP3A4, CYP2D6
Codeine phosphate (USP) D02101 UGT2B7, UGT2B4; CYP3A4, CYP2D6
Codeine phosphate and chlorpheniramine maleate D12312 UGT2B7, UGT2B4; CYP3A4, CYP2D6
Codeine polistirex (USAN) D03579 UGT2B7, UGT2B4; CYP3A4, CYP2D6
Codeine sulfate (USP) D03580 UGT2B7, UGT2B4; CYP3A4, CYP2D6
Colchicine (JP18/USP) D00570 CYP3A4
Colforsin (USAN/INN) D03584 CYP3A
Colforsin daropate hydrochloride (JAN) D01697 CYP3A
Compound oxycodone (JP18) D02175 CYP3A4; CYP2D6
Conivaptan (INN) D07748 CYP3A CYP3A
Conivaptan hydrochloride (JAN/USAN) D01236 CYP3A CYP3A
Copanlisib (USAN/INN) D10867 CYP3A; CYP1A1
Copanlisib hydrochloride (USAN) D10797 CYP3A; CYP1A1
Copanlisib hydrochloride hydrate (JAN) D10798 CYP3A; CYP1A1
Crizotinib (JAN/USAN/INN) D09731 CYP3A4, CYP3A5 CYP2B6, CYP3A
Cyclophosphamide (INN) D07760 CYP2B6; CYP2A6, CYP2C8, CYP2C9, CYP3A4
Cyclophosphamide (USP) D00287 CYP2B6; CYP2A6, CYP2C8, CYP2C9, CYP3A4
Cyclosporine (USP) D00184 CYP3A4 CYP3A4
Dabrafenib (USAN) D10064 CYP3A4, CYP2C8 CYP3A4, CYP2C9
Dabrafenib mesylate (USAN) D10104 CYP3A4, CYP2C8 CYP3A4, CYP2C9
Daclatasvir (USAN) D10065 CYP3A4 CYP3A, UGT1A1
Daclatasvir dihydrochloride (USAN) D10105 CYP3A4 CYP3A, UGT1A1
Daclatasvir, asunaprevir and beclabuvir D10882 CYP3A CYP3A4
Dacomitinib (INN) D09883 CYP2D6
Dacomitinib (USAN) D10514 CYP2D6
Dantrolene (USAN/INN) D02347 CYP1A1, CYP1A2, CYP3A
Dantrolene sodium (USP) D02274 CYP1A1, CYP1A2, CYP3A
Dapagliflozin (JAN/USAN/INN) D08897 UGT1A9
Dapagliflozin propanediol (USAN) D09763 UGT1A9
Dapsone (USP) D00592 CYP2E1, CYP3A4
Daridorexant (USAN/INN) D11886 CYP3A4
Darifenacin (USAN/INN) D03654 CYP3A4, CYP2D6
Darifenacin hydrobromide (JAN/USAN) D01699 CYP3A4, CYP2D6
Darunavir (USAN/INN) D03656 CYP3A4 CYP3A4
Darunavir ethanolate (JAN) D06478 CYP3A4 CYP3A4
Darunavir hydrate D12637 CYP3A4 CYP3A4
Darunavir propylene glycolate D12752 CYP3A4 CYP3A4
Dasabuvir, ombitasvir, paritaprevir and ritonavir D10582 CYP3A, CYP2C8 CYP3A4, UGT1A1
Dasatinib (JAN/INN) D03658 CYP3A4, FMO3, UGT
Dasatinib (USAN) D06414 CYP3A4, FMO3, UGT
Dasatinib laurylsulfate (USAN) D12609 CYP3A4, FMO3, UGT
Debrisoquin sulfate (USAN) D03664 CYP2D6
Deferasirox (JAN/USAN/INN) D03669 UGT1A1, UGT1A3 CYP1A2, CYP2C8 CYP3A4
Deflazacort (USAN/INN) D03671 CYP3A4
Delamanid (JAN/USAN) D09785 CYP3A4, CYP1A1, CYP2D6, CYP2E1
Delavirdine (INN) D07782 CYP3A CYP3A
Delavirdine mesylate (USAN) D00895 CYP3A CYP3A
Desvenlafaxine (INN) D07793 CYP3A4, UGT
Desvenlafaxine succinate (USAN) D02570 CYP3A4, UGT
Desvenlafaxine succinate anhydrous D11619 UGT; CYP3A4
Deucravacitinib (JAN/USAN) D11817 CYP1A2; CYP2B6, CYP2D6, CES2, UGT1A9
Dexamethasone (JP18/USP/INN) D00292 CYP3A4 CYP3A4
Dexamethasone 21-acetate D07796 CYP3A4 CYP3A4
Dexamethasone 21-tebutate D07799 CYP3A4 CYP3A4
Dexamethasone 21-valerate D07800 CYP3A4 CYP3A4
Dexamethasone acefurate (USAN/INN) D02591 CYP3A4 CYP3A4
Dexamethasone acetate (JAN/USP) D02174 CYP3A4 CYP3A4
Dexamethasone beloxil (USAN) D02592 CYP3A4 CYP3A4
Dexamethasone cipecilate (JAN/INN) D07073 CYP3A4 CYP3A4
Dexamethasone dipropionate (USAN) D01632 CYP3A4 CYP3A4
Dexamethasone isonicotinate D07797 CYP3A4 CYP3A4
Dexamethasone metasulfobenzoate sodium (JAN) D01510 CYP3A4 CYP3A4
Dexamethasone palmitate (JAN) D01615 CYP3A4 CYP3A4
Dexamethasone phenylpropionate D07801 CYP3A4 CYP3A4
Dexamethasone phosphate D07802 CYP3A4 CYP3A4
Dexamethasone sodium hemisulfate D07798 CYP3A4 CYP3A4
Dexamethasone sodium phosphate (JAN/USP) D00975 CYP3A4 CYP3A4
Dexamethasone valerate (JAN) D01948 CYP3A4 CYP3A4
Dexchlorpheniramine (INN) D07803 CYP2D6, CYP3A CYP2D6
Dexchlorpheniramine maleate (USP) D00668 CYP2D6, CYP3A CYP2D6
Dexfenfluramine (INN) D07805 CYP2D6
Dexfenfluramine hydrochloride (USAN) D03713 CYP2D6
Dexlansoprazole (INN/USAN) D08903 CYP2C19, CYP3A4 CYP2C19
Dexmedetomidine (USAN/INN) D00514 CYP2A6; CYP1A2, CYP2E1, CYP2D6, CYP2C19
Dexmedetomidine hydrochloride (JAN/USP) D01205 CYP2A6; CYP1A2, CYP2E1, CYP2D6, CYP2C19
Dextroamphetamine (USAN) D03740 CYP2D6
Dextroamphetamine sulfate (USP) D02078 CYP2D6
Dextromethorphan (USP) D03742 CYP2D6
Dextromethorphan hydrobromide (USP) D00848 CYP2D6
Dextromethorphan hydrobromide and bupropion hydrochloride D12493 CYP2D6
Dextromethorphan hydrobromide and potassium cresolsulfonate D04340 CYP2D6, CYP3A4
Dextromethorphan polistirex (USAN) D03744 CYP2D6
Diazepam (JP18/USP/INN) D00293 CYP2C19, CYP3A4
Diclofenac (USAN/INN) D07816 CYP2C9
Diclofenac calcium D07819 CYP2C9
Diclofenac diethylamine D07817 CYP2C9
Diclofenac epolamine D07818 CYP2C9
Diclofenac potassium (USP) D00903 CYP2C9
Diclofenac sodium (JP18/USP) D00904 CYP2C9
Dienogest (JAN/USAN/INN) D03799 CYP3A4
Dienogest and estradiol valerate D10461 CYP3A
Digitoxin (JAN/USP/INN) D00297 CYP3A
Dihydrocodeine (INN) D07831 UGT2B7, UGT2B4; CYP3A4, CYP2D6
Dihydrocodeine bitartrate (USP) D03825 UGT2B7, UGT2B4; CYP3A4, CYP2D6
Dihydrocodeine phosphate (JP18) D01481 UGT2B7, UGT2B4; CYP3A4, CYP2D6
Dihydrocodeine phosphate, dl-methylephedrine hydrochloride and Chlorpheniramine maleate D04313 UGT2B7, UGT2B4; CYP3A4, CYP2D6
Dihydrocodeine phosphate, ephedrine hydrochloride and ammmonium chloride D04338 UGT2B7, UGT2B4; CYP3A4, CYP2D6
Dihydrocodeine thiocyanate D07832 UGT2B7, UGT2B4; CYP3A4, CYP2D6
Dihydroergotamine (INN) D07837 CYP3A4
Dihydroergotamine mesylate (USP) D02211 CYP3A4
Dihydroergotamine tartrate D07838 CYP3A4
Dihydroergotoxine D07839 CYP3A4
Diltiazem (INN) D07845 CYP3A4
Diltiazem hydrochloride (JP18/USP) D00616 CYP3A4
Diltiazem malate (USAN) D03830 CYP3A4
Disopyramide (JP18/USAN/INN) D00303 CYP3A4
Disopyramide phosphate (JAN/USP) D00637 CYP3A4
Disulfiram (JP18/USP/INN) D00131 CYP2E1, CYP1A2
Docetaxel (JAN/INN) D07866 CYP3A4
Docetaxel (USP) D02165 CYP3A4
Dolasetron (INN) D07867 CYP2D6, CYP3A
Dolasetron mesylate (USP) D00725 CYP2D6, CYP3A
Dolutegravir (USAN) D10066 UGT1A1; CYP3A4
Dolutegravir sodium (JAN/USAN) D10113 UGT1A1; CYP3A4
Dolutegravir sodium and rilpivirine hydrochloride D11282 CYP3A, UGT1A1
Dolutegravir, abacavir and lamivudine D10600 UGT1A1; CYP3A4
Domperidone (JP18/USAN/INN) D01745 CYP3A4
Domperidone maleate D07868 CYP3A4
Donepezil (JAN/INN) D07869 CYP3A4; CYP2D6
Donepezil hydrochloride (JP18/USP) D00670 CYP3A4; CYP2D6
Dopamine (INN) D07870 MAOB, COMT
Dopamine hydrochloride (JP18/USP) D00633 MAOB, COMT
Doravirine (JAN/USAN/INN) D10624 CYP3A
Doravirine, lamivudine and tenofovir disoproxil D11396 CYP3A
Dorzolamide (INN) D07871 CYP2C9, CYP2C19, CYP3A4
Dorzolamide hydrochloride (JP18/USP) D00653 CYP2C9, CYP2C19, CYP3A4
Dorzolamide hydrochloride and timolol maleate (JP18) D08493 CYP2C9, CYP2C19, CYP3A4, CYP2D6
Dosulepin (INN) D07872 CYP2D6
Dothiepin hydrochloride (USAN) D01546 CYP2D6
Doxapram (INN) D07873 CYP3A4, CYP3A5
Doxapram hydrochloride (USP) D01872 CYP3A4, CYP3A5
Doxepin (INN) D07875 CYP2C19, CYP2D6; CYP1A2, CYP2C9
Doxepin hydrochloride (USP) D00814 CYP2C19, CYP2D6; CYP1A2, CYP2C9
Dronedarone (INN) D02537 CYP3A CYP3A, CYP2D6
Dronedarone hydrochloride (USP) D03914 CYP3A CYP3A, CYP2D6
Droperidol and fentanyl citrate D03852 CYP3A4
Drospirenone (JAN/USP/INN) D03917 CYP3A4
Drospirenone and estradiol D12497 CYP3A4
Drospirenone and ethinylestradiol D09741 CYP3A4
Drospirenone, ethinyl estradiol and levomefolate calcium D12130 CYP3A4
Duloxetine (INN) D07880 CYP1A2; CYP2D6 CYP2D6
Duloxetine hydrochloride (JAN/USP) D01179 CYP1A2; CYP2D6 CYP2D6
Dutasteride (JAN/USP/INN) D03820 CYP3A4, CYP3A5
Dutasteride and tamsulosin D11389 CYP3A4, CYP3A5, CYP2D6
Dydrogesterone (JP18/USP/INN) D01217 CYP3A4
Ebastine (JP18/USAN/INN) D01478 CYP2J2, CYP3A4
Efavirenz (JAN/USP/INN) D00896 CYP3A4, CYP2B6 CYP2B6, CYP3A4
Elacestrant (USAN/INN) D11671 CYP3A4; CYP2A6, CYP2C9
Elacestrant hydrochloride (USAN) D11672 CYP3A4; CYP2A6, CYP2C9
Elagolix, estradiol and norethisterone D12137 CYP3A; CYP2D6, CYP2C8, UGT
Elbasvir (JAN/USAN/INN) D10625 CYP3A
Eletriptan (INN) D07887 CYP3A4
Eletriptan hydrobromide (JAN/USAN) D01973 CYP3A4
Eletriptan hydrobromide monohydrate D11617 CYP3A4
Elexacaftor, ivacaftor and tezacaftor D11700 CYP3A
Eliglustat (USAN/INN) D09893 CYP2D6; CYP3A4
Eliglustat tartrate (JAN/USAN) D09894 CYP2D6; CYP3A4
Elvitegravir, cobicistat, emtricitabine and tenofovir disoproxil D10756 CYP3A; CYP2D6 CYP3A, CYP2D6
Empagliflozin (JAN/USAN/INN) D10459 UGT2B7, UGT1A3, UGT1A8, UGT1A9
Emtricitabine and tenofovir alafenamide D10835 CTSA, CYP3A
Emtricitabine, rilpivirine and tenofovir alafenamide D10836 CTSA, CYP3A
Encainide (INN) D07894 CYP2D6
Encainide hydrochloride (USAN) D03991 CYP2D6
Encorafenib (JAN/USAN/INN) D11053 CYP3A4
Enflurane (JP18/USP/INN) D00543 CYP2E1
Enoxacin (USAN/INN) D00310 CYP1A2
Enoxacin hydrate (JP18) D05461 CYP1A2
Ensitrelvir (USAN/INN) D12619 CYP3A CYP3A
Ensitrelvir fumarate (USAN) D12353 CYP3A CYP3A
Entacapone (JP18/USP/INN) D00781 CYP2C9, COMT
Entrectinib (JAN/USAN/INN) D10926 CYP3A4 CYP3A
Enzalutamide (JAN/USAN) D10218 CYP2C8; CYP3A4
Epinephrine (USP/INN) D00095 COMT, MAO
Epinephrine and lidocaine hydrochloride D04052 CYP1A2, CYP3A4
Epinephrine bitartrate (JAN/USP) D02149 COMT, MAO
Epinephrine hydrochloride (JAN) D00996 COMT, MAO
Eplerenone (JP18/USAN/INN) D01115 CYP3A4
Erdafitinib (JAN/USAN/INN) D10927 CYP2C9, CYP3A4
Ergoloid mesylates (USP) D02268 CYP3A4
Ergometrine (INN) D07905 CYP3A4
Ergonovine maleate (USP) D01163 CYP3A4
Ergotamine (INN) D07906 CYP3A4
Ergotamine tartrate (JP18/USP) D00679 CYP3A4
Eribulin mesylate (USAN) D08914 CYP3A4
Erlotinib (INN) D07907 CYP3A4, CYP1A2
Erlotinib hydrochloride (JAN/USAN) D04023 CYP3A4, CYP1A2
Ertugliflozin (USAN/INN) D10313 UGT1A9, UGT2B7
Ertugliflozin and sitagliptin D11066 UGT1A9, UGT2B7
Ertugliflozin pidolate D11043 UGT1A9, UGT2B7
Erythromycin (JP18/USP/INN) D00140 CYP3A CYP3A
Erythromycin acistrate (USAN) D02523 CYP3A CYP3A
Erythromycin estolate (USP) D00851 CYP3A CYP3A
Erythromycin ethylsuccinate (JP18/USP) D01361 CYP3A CYP3A
Erythromycin gluceptate (USP) D02524 CYP3A CYP3A
Erythromycin lactobionate (JP18/USP) D02009 CYP3A CYP3A
Erythromycin propionate (USAN) D02525 CYP3A CYP3A
Erythromycin salnacedin (USAN) D04054 CYP3A CYP3A
Erythromycin stearate (JP18/USP) D02184 CYP3A CYP3A
Erythromycin stinoprate (INN) D07910 CYP3A CYP3A
Erythromycin thiocyanate D07909 CYP3A CYP3A
Esaxerenone (JAN/INN) D10892 CYP3A
Escitalopram (INN) D07913 CYP3A4, CYP2C19, CYP2D6; MAO, AOX1 CYP2D6
Escitalopram oxalate (JAN/USP) D02567 CYP3A4, CYP2C19, CYP2D6; MAO, AOX1 CYP2D6
Esflurbiprofen (JAN) D10254 CYP2C9
Esflurbiprofen and mentha oil D10746 CYP2C9
Esketamine (USAN/INN) D07283 CYP2B6, CYP3A4; CYP2C9, CYP2C19, UGT
Esketamine hydrochloride (JAN/USAN) D10627 CYP2B6, CYP3A4; CYP2C9, CYP2C19, UGT
Eslicarbazepine (USAN/INN) D09215 CYP2C19 CYP3A4
Eslicarbazepine acetate (USAN) D09612 CYP2C19 CYP3A4
Esomeprazole (INN) D07917 CYP2C19; CYP3A4
Esomeprazole magnesium (USP) D01984 CYP2C19; CYP3A4
Esomeprazole magnesium dihydrate D11114 CYP2C19; CYP3A4
Esomeprazole potassium (USAN) D09339 CYP2C19; CYP3A4
Esomeprazole sodium (USAN) D04056 CYP2C19; CYP3A4
Esomeprazole strontium (USAN) D10120 CYP2C19; CYP3A4
Estazolam (JP18/USP/INN) D00311 CYP3A
Estradiol (JAN/USP/INN) D00105 CYP3A4
Estradiol 17 beta-hemisuccinate D07919 CYP3A4
Estradiol acetate (USAN) D04061 CYP3A4
Estradiol and levonorgestrel D09187 CYP3A4
Estradiol and norethindrone D09188 CYP3A4
Estradiol benzoate (JP18/USP) D01953 CYP3A4
Estradiol cypionate (USP) D04063 CYP3A4
Estradiol dipropionate (JAN) D01617 CYP3A4
Estradiol enanthate (USAN) D04064 CYP3A4
Estradiol hemihydrate D07918 CYP3A4
Estradiol undecylate (USAN/INN) D04065 CYP3A4
Estradiol valerate (JAN/USP/INN) D01413 CYP3A4
Estrogens, conjugated (JAN/USP) D04070 CYP3A4
Estrone (JAN/USP/INN) D00067 CYP3A4
Estrone sodium sulfate D00312 CYP3A4
Estropipate (USP) D00948 CYP3A4
Eszopiclone (JAN/USP/INN) D02624 CYP3A4; CYP2E1
Ethinyl estradiol (USP) D00554 CYP3A4 CYP3A4
Ethinylestradiol propanesulfonate D07928 CYP3A4 CYP3A4
Ethosuximide (JP18/USP/INN) D00539 CYP3A4
Ethyl loflazepate (JP18/INN) D01293 CYP3A4
Ethylmorphine (BAN) D07929 CYP3A4
Ethylmorphine hydrochloride hydrate (JP18) D02205 CYP3A4
Etizolam (JP18/INN) D01514 CYP2C9, CYP3A4
Etrasimod (USAN) D10930 CYP2C8, CYP2C9, CYP3A4, UGT; CYP2C19, CYP2J2
Etrasimod arginine (USAN) D10931 CYP2C8, CYP2C9, CYP3A4, UGT; CYP2C19, CYP2J2
Etravirine (JAN/USAN/INN) D04112 CYP3A4, CYP2C9, CYP2C19 CYP2C9, CYP2C19 CYP3A4
Everolimus (JAN/USAN/INN) D02714 CYP3A4
Exemestane (JAN/USP/INN) D00963 CYP3A4
Ezetimibe (JAN/USP/INN) D01966 UGT
Ezetimibe and atorvastatin D10385 CYP3A4
Ezetimibe and rosuvastatin D11520 UGT
Famotidine (JP18/USP/INN) D00318 CYP1A2
Favipiravir (JAN/USAN/INN) D09537 AOX1; XDH CYP2C8, AOX1
Fedratinib (USAN/INN) D10630 CYP3A4, CYP2C19, FMO3
Fedratinib hydrochloride (USAN) D11296 CYP3A4, CYP2C19, FMO3
Felodipine (JP18/USP/INN) D00319 CYP3A4
Fenfluramine (INN) D07945 CYP1A2, CYP2B6, CYP2D6; CYP2C9, CYP2C19, CYP3A4, CYP3A5
Fenfluramine hydrochloride (JAN/USAN) D04148 CYP1A2, CYP2B6, CYP2D6; CYP2C9, CYP2C19, CYP3A4, CYP3A5
Fenofibrate (JP18/USP/INN) D00565 UGT
Fentanyl (JAN/USP/INN) D00320 CYP3A4
Fentanyl citrate (JP18/USP) D01399 CYP3A4
Fentanyl hydrochloride (JAN) D10811 CYP3A4
Fesoterodine (INN) D07226 CYP2D6, CYP3A4
Fesoterodine fumarate (JAN/USAN) D08923 CYP2D6, CYP3A4
Fexinidazole (USAN/INN) D11252 CYP3A4
Fezolinetant (USAN) D11976 CYP1A2; CYP2C9, CYP2C19
Fidaxomicin (JAN/USAN) D09394 CYP2C19, CYP2C9, CYP3A4
Filgotinib (USAN/INN) D10871 CES1, CES2
Filgotinib hydrochloride (USAN) D10872 CES1, CES2
Filgotinib maleate (JAN/USAN) D11106 CES1, CES2
Finasteride (JAN/USP/INN) D00321 CYP3A4
Finasteride and tadalafil D12486 CYP3A4
Finerenone (JAN/USAN/INN) D10633 CYP3A4; CYP2C8
Fingolimod (INN) D10001 CYP4F2
Fingolimod hydrochloride (JAN/USAN) D04187 CYP4F2
Fingolimod lauryl sulfate D12549 CYP4F2
Flecainide (INN) D07962 CYP2D6
Flecainide acetate (JP18/USP) D00638 CYP2D6
Flibanserin (USAN/INN) D02577 CYP3A4; CYP2C19
Fluconazole (JP18/USP/INN) D00322 CYP2C19, CYP2C9, CYP3A4
Flunarizine (INN) D07971 CYP2D6
Flunarizine hydrochloride (JAN/USAN) D01303 CYP2D6
Flunisolide (JAN/USP) D00324 CYP3A4
Flunisolide acetate (USAN) D04214 CYP3A4
Fluorouracil (JP18/USP/INN) D00584 DPYD
Fluorouracil sodium salt D07974 DPYD
Fluoxetine (USAN/INN) D00326 CYP2C9, CYP2D6 CYP2C19, CYP2D6, CYP3A
Fluoxetine hydrochloride (JAN/USP) D00823 CYP2C9, CYP2D6 CYP2C19, CYP2D6, CYP3A
Fluphenazine (INN) D07977 CYP2D6
Fluphenazine decanoate (JAN/USP) D00793 CYP2D6
Fluphenazine enanthate (JP18/USP) D00792 CYP2D6
Fluphenazine hydrochloride (JAN/USP) D00791 CYP2D6
Fluphenazine maleate (JAN) D02163 CYP2D6
Flurbiprofen (JP18/USP/INN) D00330 CYP2C9
Flurbiprofen axetil (JAN) D01475 CYP2C9
Flurbiprofen sodium (USP) D02290 CYP2C9
Fluticasone (INN) D07981 CYP3A4
Fluticasone furoate (JAN/USAN/INN) D06315 CYP3A4
Fluticasone furoate and vilanterol trifenatate D10501 CYP3A4
Fluticasone propionate (JAN/USP) D01708 CYP3A4
Fluticasone propionate and formoterol fumarate hydrate D10506 CYP3A4, UGT
Fluvastatin (INN) D07983 CYP2C9, CYP3A4 CYP2C9
Fluvastatin sodium (JAN/USP) D00892 CYP2C9, CYP3A4 CYP2C9
Fluvoxamine (INN) D07984 CYP2D6 CYP1A2, CYP2C19; CYP2C9, CYP2D6, CYP3A4
Fluvoxamine maleate (JP18/USP) D00824 CYP2D6 CYP1A2, CYP2C19; CYP2C9, CYP2D6, CYP3A4
Fomepizole (JAN/USAN/INN) D00707 CYP2D6, CYP2E1, CYP1A2, CYP2A6, CYP2C9, CYP3A4
Formoterol (INN) D07990 UGT
Formoterol fumarate (USP) D01373 UGT
Formoterol fumarate hydrate (JP18) D05277 UGT
Fosamprenavir (INN) D02497 CYP3A4 CYP3A4
Fosamprenavir calcium (USAN) D03835 CYP3A4 CYP3A4
Fosamprenavir calcium hydrate (JAN) D02867 CYP3A4 CYP3A4
Fosamprenavir sodium (USAN) D03837 CYP3A4 CYP3A4
Fosaprepitant (INN) D10895 CYP3A4 CYP3A4 CYP3A4, CYP2C9
Fosaprepitant dimeglumine (USAN) D06597 CYP3A4 CYP3A4 CYP3A4, CYP2C9
Fosfluconazole (JAN/INN) D01429 CYP2C19, CYP2C9, CYP3A4
Foslevodopa and foscarbidopa D12494 COMT, DDC
Fosnetupitant and palonosetron hydrochloride D10572 CYP3A4; CYP2C9, CYP2D6
Fosphenytoin (INN) D07993 CYP2C9; CYP2C19 CYP3A4, CYP2B6
Fosphenytoin sodium (USP) D02096 CYP2C9; CYP2C19 CYP3A4, CYP2B6
Fosphenytoin sodium hydrate (JAN) D07595 CYP2C9; CYP2C19 CYP3A4, CYP2B6
Fosravuconazole L-lysine ethanolate (JAN) D10762 CYP3A
Fostamatinib (USAN) D09347 CYP3A4 CYP3A
Fostamatinib disodium (USAN) D09348 CYP3A4 CYP3A
Fostemsavir (USAN) D10707 CYP3A
Fostemsavir tromethamine (USAN) D10708 CYP3A
Fruquintinib (JAN/USAN) D11977 CYP3A; CYP2C8, CYP2C9, CYP2C19
Fulvestrant (JAN/USP/INN) D01161 CYP3A4
Galantamine (USAN/INN) D04292 CYP2D6, CYP3A4
Galantamine hydrobromide (JAN/USP) D02173 CYP2D6, CYP3A4
Ganaxolone (USAN/INN) D04300 CYP3A4, CYP3A5, CYP2B6, CYP2C19, CYP2D6
Gemfibrozil (JAN/USP/INN) D00334 CYP2C8
Gemtuzumab ozogamicin (USAN) D03259 CYP3A4
Gepirone hydrochloride (USAN) D04314 CYP3A4
Gilteritinib (USAN/INN) D10709 CYP3A4
Gilteritinib fumarate (JAN/USAN) D10800 CYP3A4
Glimepiride (JP18/USP/INN) D00593 CYP2C9
Glyburide (USP) D00336 CYP2C9, CYP3A4
Glycopyrronium bromide and indacaterol maleate D10505 CYP3A4
Granisetron (JAN/USAN/INN) D04370 CYP3A4, CYP1A1
Granisetron hydrochloride (JAN/USP) D00677 CYP3A4, CYP1A1
Grazoprevir (USAN) D10639 CYP3A CYP3A
Grazoprevir (USAN/INN) D11565 CYP3A CYP3A
Guanfacine (INN) D08031 CYP3A4, CYP3A5
Guanfacine hydrochloride (JAN/USP) D00606 CYP3A4, CYP3A5
Halofantrine (INN) D08033 CYP2D6
Halofantrine hydrochloride (USAN) D02485 CYP2D6
Haloperidol (JP18/USP/INN) D00136 CYP2D6, CYP3A4
Haloperidol decanoate (JAN/USP) D01898 CYP2D6, CYP3A4
Haloperidol lactate D08035 CYP2D6, CYP3A4
Halothane (JP18/USP/INN) D00542 CYP2E1, CYP3A4
Hemin (JAN) D10003 CYP3A4, CYP2D6
Hydralazine (INN) D08044 NAT CYP2D6
Hydralazine hydrochloride (JP18/USP) D01302 NAT CYP2D6
Hydralazine polistirex (USAN) D04458 NAT CYP2D6
Hydrocodone (INN) D08045 CYP3A4; CYP2D6, CYP2B6, CYP2C19
Hydrocodone bitartrate (USP) D03725 CYP3A4; CYP2D6, CYP2B6, CYP2C19
Hydrocodone hydrochloride D08046 CYP3A4; CYP2D6, CYP2B6, CYP2C19
Hydrocodone polistirex (USAN) D04461 CYP3A4; CYP2D6, CYP2B6, CYP2C19
Hydrocortisone (JP18/USP/INN) D00088 CYP3A
Hydrocortisone aceponate (INN) D06876 CYP3A
Hydrocortisone acetate (JP18/USP) D00165 CYP3A
Hydrocortisone butyrate (JP18/USP) D01619 CYP3A
Hydrocortisone caproate (JAN) D09796 CYP3A
Hydrocortisone cypionate D00976 CYP3A
Hydrocortisone hemisuccinate (USP) D04467 CYP3A
Hydrocortisone probutate (USAN) D01886 CYP3A
Hydrocortisone sodium phosphate (JP18/USP) D00977 CYP3A
Hydrocortisone sodium succinate (JP18/USP) D00978 CYP3A
Hydrocortisone succinate (JP18) D01442 CYP3A
Hydrocortisone valerate (USP) D02288 CYP3A
Hydromorphone (INN) D08047 UGT
Hydromorphone hydrochloride (JAN/USP) D00839 UGT
Hydroxychloroquine (INN) D08050 CYP2C8, CYP3A4
Hydroxychloroquine sulfate (JAN/USP) D02114 CYP2C8, CYP3A4
Ibrutinib (JAN/USAN) D10223 CYP3A
Ibuprofen (JP18/USP/INN) D00126 CYP2C9
Ibuprofen aluminum (USAN) D04490 CYP2C9
Ibuprofen arginine salt D08058 CYP2C9
Ibuprofen lysine (USAN) D06606 CYP2C9
Ibuprofen piconol (JP18/USAN) D01122 CYP2C9
Ibuprofen sodium D08059 CYP2C9
Ibuprofen sodium (USAN) D09760 CYP2C9
Ibuprofen trelamine (USAN) D12597 CYP2C9
Ibuprofen trelamine hydrochloride (USAN) D12598 CYP2C9
Idelalisib (JAN/USAN/INN) D10560 CYP3A; UGT1A4
Ifosfamide (JAN/USP/INN) D00343 CYP3A4
Iguratimod (JAN/INN) D01146 NAT
Iloperidone (USAN/INN) D02666 CYP3A4, CYP2D6
Imatinib (INN) D08066 CYP3A4
Imatinib mesylate (USAN) D01441 CYP3A4
Imidafenacin (JAN/INN) D06273 CYP3A4, UGT1A4
Imipramine (INN) D08070 CYP2D6; CYP1A2, CYP3A4, CYP2C19
Imipramine hydrochloride (JP18/USP) D00815 CYP2D6; CYP1A2, CYP3A4, CYP2C19
Imipramine pamoate (USP) D08071 CYP2D6; CYP1A2, CYP3A4, CYP2C19
Indacaterol (USAN/INN) D09318 CYP3A4
Indacaterol acetate (JAN) D11009 CYP3A4
Indacaterol maleate (JAN/USAN) D09319 CYP3A4
Indinavir (USAN) D03833 CYP3A4 CYP3A4
Indinavir sulfate (USP) D00897 CYP3A4 CYP3A4
Indinavir sulfate ethanolate (JAN) D02861 CYP3A4 CYP3A4
Insulin aspart (USP/INN) D04475 CYP1A2
Insulin detemir (USAN/INN) D04539 CYP1A2
Insulin glargine (USAN/INN) D03250 CYP1A2
Insulin glulisine (USAN/INN) D04540 CYP1A2
Insulin human (USP/INN) D03230 CYP1A2
Insulin injection, biphasic isophane (BAN) D08080 CYP1A2
Insulin lispro (USP/INN) D04477 CYP1A2
Insulin zinc (USP) D04551 CYP1A2
Insulin zinc, extended (USP) D04549 CYP1A2
Insulin zinc, prompt (USP) D04550 CYP1A2
Insulin, isophane (USP) D04547 CYP1A2
Ipragliflozin (INN) D10196 UGT2B7
Ipragliflozin L-proline (JAN) D10200 UGT2B7
Iptacopan (USAN/INN) D12251 CYP2C8; CYP2D6, UGT1A1, UGT1A3, UGT1A8
Iptacopan hydrochloride (USAN) D12252 CYP2C8; CYP2D6, UGT1A1, UGT1A3, UGT1A8
Irbesartan (JP18/USP/INN) D00523 CYP2C9
Irbesartan and amlodipine besilate (JP18) D10243 CYP3A4
Irbesartan and trichlormethiazide D10480 CYP2C9, UGT
Irinotecan (INN) D08086 CES; CYP3A4, UGT1A1
Irinotecan hydrochloride (USP) D01061 CES; CYP3A4, UGT1A1
Irinotecan sucrosofate (USAN) D10642 CES; CYP3A4, UGT1A1
Isavuconazonium (USAN) D10644 CYP3A CYP3A, UGT CYP2B6
Isavuconazonium sulfate (JAN/USAN) D10643 CYP3A CYP3A, UGT CYP2B6
Isoprenaline (INN) D08090 COMT
Isopropylantipyrine, ergotamine tartrate and anhydrous caffeine D07585 CYP3A4
Isoproterenol hydrochloride (USP) D01390 COMT
Isoproterenol sulfate (USP) D02066 COMT
Istradefylline (JAN/USAN/INN) D04641 CYP1A1, CYP3A4, CYP3A5 CYP3A4, CYP3A5
Itopride (INN) D08094 FMO1, FMO3
Itopride hydrochloride (JAN) D02729 FMO1, FMO3
Itraconazole (JP18/USP) D00350 CYP3A4 CYP3A4
Ivabradine (USAN/INN) D07165 CYP3A4
Ivabradine hydrochloride (JAN/USAN) D08095 CYP3A4
Ivermectin (JAN/USP/INN) D00804 CYP3A4
Ixabepilone (JAN/USAN/INN) D04645 CYP3A4
Josamycin (JP18/USAN/INN) D01235 CYP3A4
Josamycin propionate (JP18) D05351 CYP3A4
Ketoconazole (JP18/USP) D00351 CYP3A4 CYP3A4
Lacosamide (JAN/USAN/INN) D07299 CYP3A4, CYP2C9, CYP2C19 CYP2C19
Lafutidine (JP18/INN) D01131 CYP3A4, CYP2D6
Lamivudine, nevirapine and zidovudine D11521 CYP3A, CYP2B6, UGT CYP3A, CYP2B6
Lamotrigine (JAN/USP/INN) D00354 UGT1A4
Lanoconazole (JP18/INN) D01092 CYP2C9
Lansoprazole (JP18/USP/INN) D00355 CYP2C19, CYP3A4 CYP2C19
Lansoprazole, amoxicillin hydrate and metronidazole D09742 CYP2C19, CYP3A4
Lapatinib (INN) D08108 CYP3A4, CYP3A5; CYP2C19, CYP2C8
Lapatinib ditosylate (USAN) D04024 CYP3A4, CYP3A5; CYP2C19, CYP2C8
Larotrectinib (USAN/INN) D11137 CYP3A
Larotrectinib sulfate (JAN/USAN) D11138 CYP3A
Lefamulin (USAN/INN) D11631 CYP3A4
Lefamulin acetate (USAN) D11632 CYP3A4
Leflunomide (JAN/USP/INN) D00749 CYP3A4 CYP2C9
Lemborexant (JAN/USAN/INN) D11022 CYP3A4; CYP3A5
Lenacapavir (USAN/INN) D12161 UGT1A1, CYP3A
Lenacapavir sodium (JAN/USAN) D12162 UGT1A1, CYP3A
Leniolisib (USAN/INN) D11158 CYP3A4
Leniolisib phosphate (USAN) D11159 CYP3A4
Lenvatinib (USAN/INN) D09919 CYP3A
Lenvatinib mesylate (USAN) D09920 CYP3A
Lercanidipine (INN) D08111 CYP3A
Lercanidipine hydrochloride (JAN/USAN) D01849 CYP3A
Lesinurad (USAN/INN) D09921 CYP2C9
Lesinurad sodium (USAN) D09922 CYP2C9
Letermovir (JAN/USAN/INN) D10801 CYP3A CYP2C9, CYP2C19
Letrozole (JAN/USP/INN) D00964 CYP3A4, CYP2A6 CYP2A6
Levobupivacaine (INN) D08116 CYP3A4, CYP1A2
Levobupivacaine hydrochloride (JAN/USAN) D01287 CYP3A4, CYP1A2
Levocetirizine (USAN/INN) D07402 CYP3A4
Levocetirizine dihydrochloride (USP) D08118 CYP3A4
Levomethadyl acetate (USAN) D04716 CYP3A4
Levomethadyl acetate hydrochloride (USAN) D00840 CYP3A4
Lidocaine (JP18/USP/INN) D00358 CYP1A2, CYP3A4
Lidocaine and prilocaine D02740 CYP1A2, CYP3A4
Lidocaine and tetracaine D11553 CYP1A2; CYP3A4
Lidocaine hydrochloride (JAN/USP) D02086 CYP1A2, CYP3A4
Lidocaine hydrochloride and epinephrine bitartrate D04813 CYP1A2, CYP3A4
Lidocaine hydrochloride monohydrate D08127 CYP1A2, CYP3A4
Lomitapide (USAN/INN) D09637 CYP3A4
Lomitapide mesylate (USAN) D09638 CYP3A4
Loperamide (INN) D08144 CYP3A4, CYP2C8
Loperamide hydrochloride (JAN/USP) D00729 CYP3A4, CYP2C8
Loperamide oxide (INN) D07113 CYP3A4, CYP2C8
Lopinavir (JAN/USP/INN) D01425 CYP3A CYP3A
Lopinavir and ritonavir D02498 CYP3A CYP3A
Loratadine (JAN/USP/INN) D00364 CYP2D6, CYP3A4
Lorazepam (JP18/USP/INN) D00365 UGT2B7, UGT2B15
Lorlatinib (JAN/USAN/INN) D11012 CYP3A CYP3A
Lornoxicam (JAN/USAN/INN) D01866 CYP2C9
Losartan (INN) D08146 CYP2C9
Losartan potassium (JP18/USP) D00357 CYP2C9
Losartan potassium and hydrochlorothiazide (JP18) D07895 CYP2C9
Lovastatin (USP/INN) D00359 CYP3A4
Loxapine (USAN/INN) D02340 CYP1A2, CYP3A4, CYP2D6
Loxapine hydrochloride D08148 CYP1A2, CYP3A4, CYP2D6
Loxapine succinate (USP) D00794 CYP1A2, CYP3A4, CYP2D6
Luliconazole (JAN/USAN/INN) D01980 CYP2B6, CYP2C8, CYP2C19, CYP3A4
Lurasidone hydrochloride (JAN/USAN) D04820 CYP3A4
Lusutrombopag (JAN/USAN/INN) D10476 CYP4A11
Macitentan (JAN/USAN) D10135 CYP3A4
Manidipine (INN) D08155 CYP3A4
Manidipine hydrochloride (JP18) D01553 CYP3A4
Maprotiline (USAN) D02566 CYP2D6
Maprotiline hydrochloride (JP18/USP) D00818 CYP2D6
Maraviroc (JAN/INN) D06670 CYP3A4
Maribavir (JAN/USAN/INN) D04859 CYP3A4; CYP1A2
Mavacamten (JAN/USAN/INN) D12265 CYP2C19; CYP3A4, CYP2C9
Maxacalcitol (JAN/USAN/INN) D01098 CYP3A4
Mefenamic acid (JP18/USP/INN) D00151 CYP2C9
Mefloquine (USAN/INN) D04895 CYP3A
Mefloquine hydrochloride (JP18/USP) D00831 CYP3A
Melatonin (JAN) D08170 CYP1A2
Meloxicam (JAN/USP/INN) D00969 CYP2C9; CYP3A4
Mepenzolate bromide and phenobarbital D04059 CYP3A
Mephenytoin (USP/INN) D00375 CYP2C19
Mephobarbital (JAN/USP) D00700 CYP2C19
Mequitazine (JP18/INN) D01324 CYP2D6
Metamfetamine (INN) D08187 CYP2D6
Metformin hydrochloride and saxagliptin hydrochloride D10263 CYP3A4, CYP3A5
Methadone (BAN) D08195 CYP3A4, CYP2B6; CYP2C8, CYP2C9, CYP2C19, CYP2D6 CYP3A4, CYP2B6
Methadone hydrochloride (JAN/USP) D02102 CYP3A4, CYP2B6; CYP2C8, CYP2C9, CYP2C19, CYP2D6 CYP3A4, CYP2B6
Methamphetamine hydrochloride (JP18/USP) D02242 CYP2D6
Methoxsalen (JP18/USP) D00139 CYP2A6
Methoxyflurane (USP/INN) D00544 CYP2E1, CYP3A4
Methylene blue (USP) D02312 CYP1A2, CYP2B6, CYP2C9, CYP2C19
Methylergometrine (INN) D08207 CYP3A4
Methylergonovine maleate (USP) D00680 CYP3A4
Methylprednisolone (JP18/USP/INN) D00407 CYP3A4
Methylprednisolone aceponate (INN) D07203 CYP3A4
Methylprednisolone acetate (JAN/USP) D00979 CYP3A4
Methylprednisolone hemisuccinate (USP) D05000 CYP3A4
Methylprednisolone sodium phosphate (USAN) D05001 CYP3A4
Methylprednisolone sodium succinate (JAN/USP) D00751 CYP3A4
Methylprednisolone suleptanate (USAN/INN) D05002 CYP3A4
Methylthioninium chloride hydrate (JAN) D10537 CYP1A2, CYP2B6, CYP2C9, CYP2C19
Metoclopramide (JP18/INN) D00726 CYP2D6 CYP2D6
Metoclopramide hydrochloride (JAN) D02213 CYP2D6 CYP2D6
Metoclopramide hydrochloride (USP) D05008 CYP2D6 CYP2D6
Metoprolol (USAN/INN) D02358 CYP2D6
Metoprolol and hydrochlorothiazide D10273 CYP2D6
Metoprolol fumarate (USP) D05011 CYP2D6
Metoprolol succinate (USP) D00635 CYP2D6
Metoprolol tartrate (JP18/USP) D00601 CYP2D6
Metronidazole (JP18/USP/INN) D00409 CYP2A6 CYP2C9
Metronidazole benzoate (USP) D08214 CYP2A6 CYP2C9
Metronidazole hydrochloride (USAN) D05016 CYP2A6 CYP2C9
Metronidazole phosphate (USAN) D05017 CYP2A6 CYP2C9
Mexazolam (JAN/INN) D01316 CYP3A4
Mexiletine (INN) D08215 CYP1A2, CYP2D6
Mexiletine hydrochloride (JP18/USP) D00639 CYP1A2, CYP2D6
Mianserin (INN) D08216 CYP3A4, CYP1A2, CYP2D6
Mianserin hydrochloride (JAN/USAN) D01358 CYP3A4, CYP1A2, CYP2D6
Mibefradil (INN) D08217 CYP3A, CYP1A2, CYP2D6
Mibefradil dihydrochloride (USAN) D05024 CYP3A, CYP1A2, CYP2D6
Miconazole (JP18/USP/INN) D00416 CYP2C9, CYP3A
Miconazole nitrate (JP18/USP) D00882 CYP2C9, CYP3A
Midazolam (JAN/USP/INN) D00550 CYP3A4
Midazolam hydrochloride (USAN) D00696 CYP3A4
Midazolam maleate (USAN) D05028 CYP3A4
Midecamycin (JP18/INN) D01339 CYP3A4
Midecamycin acetate (JP18) D01636 CYP3A4
Midodrine (INN) D08220 CYP2D6
Midodrine hydrochloride (JAN/USP) D01307 CYP2D6
Midostaurin (JAN/USAN/INN) D05029 CYP3A4
Mifepristone (JAN/USAN/INN) D00585 CYP3A4 CYP3A
Mifepristone and misoprostol D12586 CYP3A CYP3A
Milrinone (JAN/USP/INN) D00417 UGT
Milrinone lactate D02085 UGT
Minaprine (USAN/INN) D05039 CYP2D6
Minaprine hydrochloride (USAN) D05040 CYP2D6
Mirabegron (JAN/USAN/INN) D09535 CYP3A4 CYP2D6
Mirtazapine (JAN/USP/INN) D00563 CYP1A2, CYP2D6, CYP3A4
Mirtazapine hydrate (JAN) D11056 CYP1A2, CYP2D6, CYP3A4
Mirvetuximab soravtansine (USAN/INN) D10954 CYP3A4
Mitiglinide calcium hydrate (JP18) D01854 UGT
Mobocertinib (USAN/INN) D12001 CYP3A
Mobocertinib succinate (JAN) D11969 CYP3A
Moclobemide (USAN/INN) D02561 CYP2C19 CYP2D6, CYP2C19
Modafinil (JAN/USP/INN) D01832 CYP3A4 CYP2C9, CYP2C19 CYP1A2, CYP2B6, CYP3A4
Mofezolac (JAN/INN) D01718 CYP2C9
Momelotinib (USAN/INN) D10315 CYP3A4, CYP2C8, CYP2C9, CYP2C19, CYP1A2
Momelotinib dihydrochloride (USAN) D10358 CYP3A4, CYP2C8, CYP2C9, CYP2C19, CYP1A2
Momelotinib hydrochloride hydrate (JAN) D10889 CYP3A4, CYP2C8, CYP2C9, CYP2C19, CYP1A2
Mometasone (INN) D08227 CYP3A4
Mometasone furoate (JAN/USP) D00690 CYP3A4
Mometasone furoate hydrate (JAN) D03325 CYP3A4
Montelukast (INN) D08229 CYP2C8, CYP2C9, CYP3A4
Montelukast sodium (JP18/USP) D00529 CYP2C8, CYP2C9, CYP3A4
Moricizine (USAN) D05077 CYP1A2
Moricizine hydrochloride (USP) D02087 CYP1A2
Morphine (BAN) D08233 UGT
Morphine hydrochloride hydrate (JP18) D02271 UGT
Morphine sulfate (USP) D00842 UGT
Morphine tartrate D08234 UGT
Mosapride (INN) D08236 CYP3A4
Mosapride citrate hydrate (JP18) D01994 CYP3A4
Mozavaptane hydrochloride (JAN) D01855 CYP3A4, CYP2C8
Naldemedine (USAN/INN) D10188 CYP3A4
Naldemedine tosylate (JAN/USAN) D10478 CYP3A4
Nalfurafine hydrochloride (JAN/USAN) D06405 CYP3A4
Naloxegol (USAN/INN) D10479 CYP3A
Naloxegol oxalate (USAN) D10375 CYP3A
Naproxen and esomeprazole magnesium D11576 CYP2C9, CYP1A2, CYP2C19; CYP3A4
Naratriptan (INN) D08255 CYP1A2, CYP2C9, CYP2D6, CYP2E1, CYP3A4, CYP3A5
Naratriptan hydrochloride (JAN/USP) D00674 CYP1A2, CYP2C9, CYP2D6, CYP2E1, CYP3A4, CYP3A5
Nateglinide (JP18/USP/INN) D01111 CYP2C9
Nebivolol (USAN/INN) D05127 CYP2D6
Nebivolol hydrochloride (USAN) D06622 CYP2D6
Nelarabine (JAN/USAN/INN) D05134 ADA
Nelfinavir (INN) D08259 CYP3A4; CYP2C19 CYP3A4
Nelfinavir mesylate (USAN/INN) D00899 CYP3A4; CYP2C19 CYP3A4
Nemonapride (JAN/INN) D01468 CYP3A4
Netupitant (USAN/INN) D05152 CYP3A CYP3A
Nevirapine (JAN/USP/INN) D00435 CYP3A4, CYP2B6, CYP2D6
Nicardipine (INN) D08270 CYP3A4
Nicardipine hydrochloride (JP18/USAN) D00617 CYP3A4
Nicotine (USP) D03365 CYP2A6 CYP1A2
Nicotine bitartrate (USAN) D05156 CYP2A6 CYP1A2
Nicotine polacrilex (USP) D05157 CYP2A6 CYP1A2
Nifedipine (JP18/USP/INN) D00437 CYP3A4
Nilotinib (USAN/INN) D08953 CYP3A4; CYP2C8
Nilotinib hydrochloride dihydrate (JAN) D12444 CYP3A4; CYP2C8
Nilotinib hydrochloride hydrate (JAN) D06413 CYP3A4; CYP2C8
Nilvadipine (JP18/USAN/INN) D01908 CYP3A4
Nimodipine (USP/INN) D00438 CYP3A4
Nintedanib (USAN/INN) D10481 UGT
Nintedanib esylate (USAN) D10396 UGT
Nirmatrelvir and ritonavir D12269 CYP3A4 CYP3A
Nirogacestat (USAN/INN) D10960 CYP3A4; CYP2C19, CYP2C9, CYP2D6
Nirogacestat hydrobromide (USAN) D11453 CYP3A4; CYP2C19, CYP2C9, CYP2D6
Nisoldipine (JAN/USAN/INN) D00618 CYP3A4
Nitrendipine (JP18/USAN/INN) D00629 CYP3A4
Noradrenaline (JP18) D00076 COMT, MAO
Nordazepam (INN) D08283 CYP2C19, CYP3A4
Norepinephrine bitartrate (USP) D05206 COMT, MAO
Norepinephrine hydrochloride (JAN) D09794 COMT, MAO
Norepinephrine hydrochoride D08284 COMT, MAO
Norfloxacin (JP18/USP/INN) D00210 CYP1A2 CYP3A, CYP1A2
Norfloxacin nicotinate D08287 CYP1A2 CYP3A, CYP1A2
Norgestrel and ethinylestradiol tablets (JP18) D04463 CYP3A4, CYP2C9, CYP2C19
Nortriptyline (INN) D08288 CYP2D6
Nortriptyline hydrochloride (JP18/USP/INN) D00816 CYP2D6
Ofloxacin (JP18/USP/INN) D00453 CYP3A4
Ofloxacin hydrochloride D08291 CYP3A4
Olanzapine (JAN/USP/INN) D00454 CYP1A2; CYP2D6
Olanzapine pamoate (USAN) D06623 CYP1A2; CYP2D6
Olaparib (JAN/USAN/INN) D09730 CYP3A
Olmesartan medoxomil and azelnidipine D09594 CYP3A4
Olodaterol (USAN/INN) D10145 CYP2C9, CYP2C8, UGT2B7, UGT1A1, UGT1A7, UGT1A9
Olodaterol hydrochloride (JAN/USAN) D10020 CYP2C9, CYP2C8, UGT2B7, UGT1A1, UGT1A7, UGT1A9
Olutasidenib (USAN/INN) D12483 CYP3A4
Omaveloxolone (USAN/INN) D10964 CYP3A; CYP2C8, CYP2J2
Ombitasvir, paritaprevir and ritonavir D10745 CYP3A4, CYP3A5 CYP3A4
Omeprazole (JP18/USP/INN) D00455 CYP2C19; CYP3A4
Omeprazole and sodium bicarbonate D11706 CYP2C19; CYP3A4
Omeprazole magnesium (USP) D05259 CYP2C19; CYP3A4
Omeprazole magnesium, amoxicillin and rifabutin D11858 CYP3A, CYP2C19 CYP2C19 CYP3A
Omeprazole sodium (USAN) D01207 CYP2C19; CYP3A4
Omeprazole sodium injection (JAN) D05261 CYP2C19; CYP3A4
Omeprazole, clarithromycin and amoxicillin D10246 CYP2C19, CYP3A4 CYP3A4
Omidenepag (USAN/INN) D10965 CES1
Omidenepag isopropyl (JAN) D10966 CES1
Ondansetron (JAN/USP/INN) D00456 CYP1A2, CYP3A4, CYP2D6
Ondansetron hydrochloride hydrate (JAN/USP) D00678 CYP1A2, CYP2D6, CYP3A4
Opicapone (JAN/USAN/INN) D10825 COMT
Osilodrostat (USAN/INN) D11061 CYP3A4, CYP2B6, CYP2D6, UGT
Osilodrostat phosphate (JAN/USAN) D11062 CYP3A4, CYP2B6, CYP2D6, UGT
Osimertinib mesylate (USAN) D10766 CYP3A
Oxcarbazepine (JAN/USP/INN) D00533 CYP2C19 CYP3A
Oxtriphylline (USP) D02017 CYP1A2
Oxybutynin (USAN/INN) D00465 CYP3A4, CYP3A5
Oxybutynin chloride (USP) D00722 CYP3A4, CYP3A5
Oxycodone (USAN/INN) D05312 CYP3A4; CYP2D6
Oxycodone and ibuprofen D11573 CYP3A4, CYP2A6
Oxycodone hydrochloride (USP) D00847 CYP3A4; CYP2D6
Oxycodone hydrochloride hydrate (JP18) D05462 CYP3A4; CYP2D6
Oxycodone terephthalate (USP) D03783 CYP3A4; CYP2D6
Ozenoxacin (JAN/USAN/INN) D09544 CYP3A4
Paclitaxel (JAN/USP/INN) D00491 CYP2C8, CYP3A4
Paclitaxel poliglumex (USAN/INN) D05333 CYP2C8, CYP3A4
Pacritinib (USAN/INN) D11768 CYP3A4
Palonosetron (INN) D07175 CYP1A2, CYP2D6, CYP3A4
Palonosetron hydrochloride (JAN/USP) D05343 CYP1A2, CYP2D6, CYP3A4
Palovarotene (JAN/USAN/INN) D09365 CYP3A4; CYP2C8, CYP2C19
Panobinostat (USAN/INN) D10319 CYP3A4 CYP2D6
Panobinostat lactate (JAN) D10019 CYP3A4 CYP2D6
Pantoprazole (USAN/INN) D05353 CYP2C19; CYP3A4
Pantoprazole sodium (USP) D02593 CYP2C19; CYP3A4
Paroxetine (USP/INN) D02362 CYP2D6 CYP2D6
Paroxetine hydrochloride (USP) D05374 CYP2D6 CYP2D6
Paroxetine hydrochloride hemihydrate (USP) D02260 CYP2D6 CYP2D6
Paroxetine mesylate (USAN) D05375 CYP2D6 CYP2D6
Pazufloxacin (JAN/INN) D01153 CYP1A2
Pazufloxacin mesilate (JP18) D05382 CYP1A2
Peginterferon alfa-2b (USAN/INN) D02748 CYP1A2, CYP2D6
Pemafibrate (JAN) D10711 CYP3A, CYP2C9, CYP2C8
Pemigatinib (JAN/USAN/INN) D11417 CYP3A4
Perampanel (USAN) D08964 CYP3A
Perampanel hydrate (JAN) D10780 CYP3A
Perhexiline (INN) D08340 CYP2D6
Perhexiline maleate (USAN) D05442 CYP2D6
Perphenazine (JP18/USP/INN) D00503 CYP2D6
Perphenazine decanoate D08341 CYP2D6
Perphenazine enantate D08342 CYP2D6
Perphenazine fendizoate (JAN) D04038 CYP2D6
Perphenazine hydrochloride D04965 CYP2D6
Perphenazine maleate (JP18) D02037 CYP2D6
Pexidartinib (USAN/INN) D11270 CYP3A4, UGT1A4
Pexidartinib hydrochloride (JAN/USAN) D11271 CYP3A4, UGT1A4
Phenformin (BAN) D08351 CYP2D6
Phenformin hydrochloride D08352 CYP2D6
Phenobarbital (JP18/USP/INN) D00506 CYP3A; CYP1A2, CYP2B6, CYP2C9
Phenobarbital diethylamine D08356 CYP3A; CYP1A2, CYP2B6, CYP2C9
Phenobarbital sodium (JAN/USP/INN) D00701 CYP3A; CYP1A2, CYP2B6, CYP2C9
Phentermine and topiramate D11710 CYP3A4
Phenylbutazone (JP18/USP/INN) D00510 CYP2C9
Phenylbutazone calcium D08363 CYP2C9
Phenylbutazone sodium D08364 CYP2C9
Phenylpropanolamine (INN) D08368 CYP1A2
Phenylpropanolamine hydrochloride (JAN/USP) D01224 CYP1A2
Phenylpropanolamine polistirex (USAN) D05466 CYP1A2
Phenytoin (JP18/USP/INN) D00512 CYP2C9; CYP2C19 CYP3A, CYP2B6
Phenytoin and phenobarbital D07583 CYP2C9; CYP2C19 CYP3A, CYP2B6
Phenytoin sodium (USP) D02103 CYP2C9; CYP2C19 CYP3A, CYP2B6
Phenytoin, phenobarbital and caffeine and sodium benzoate D03844 CYP2C9, CYP2C19, CYP2B6, CYP3A
Pilocarpine (JAN/USP) D00525 CYP2A6
Pilocarpine borate D08376 CYP2A6
Pilocarpine hydrochloride (JP18/USP) D02200 CYP2A6
Pilocarpine nitrate (USP) D05478 CYP2A6
Pimavanserin tartrate (USAN) D08969 CYP3A4, CYP3A5; CYP2J2, CYP2D6
Pimitespib (JAN) D11920 CYP3A
Pimozide (JP18/USP/INN) D00560 CYP3A4; CYP2D6
Pindolol (JP18/USP/INN) D00513 CYP2D6
Pioglitazone (INN) D08378 CYP2C8
Pioglitazone hydrochloride (JP18/USP) D00945 CYP2C8
Pioglitazone hydrochloride and glimepiride tablets (JP18) D09848 CYP2C8, CYP2C9
Pipemidic acid (INN) D08379 CYP1A2
Pipemidic acid hydrate (JP18) D01531 CYP1A2
Pirfenidone (JAN/USAN/INN) D01583 CYP1A2; CYP2C9, CYP2C19, CYP2D6, CYP2E1
Piroxicam (JP18/USP/INN) D00127 CYP2C9
Piroxicam betadex (USAN) D05511 CYP2C9
Piroxicam cinnamate (USAN) D05512 CYP2C9
Piroxicam olamine (USAN) D05513 CYP2C9
Pitavastatin calcium (JAN) D01862 CYP2C9
Pitavastatin calcium hydrate (JP18) D10568 CYP2C9
Pitavastatin magnesium D11092 CYP2C9
Pitolisant (USAN/INN) D10749 CYP2D6; CYP3A4
Pitolisant hydrochloride (USAN) D11490 CYP2D6; CYP3A4
Platycodon fluidextract, glycyrrhiza extract, plantago herb extract, peony root extract and dihydrocodeine phosphate D08697 UGT2B7, UGT2B4; CYP3A4, CYP2D6
Polatuzumab vedotin (USAN) D10761 CYP3A
Pomalidomide (JAN/USAN/INN) D08976 CYP1A2, CYP3A4
Ponatinib (USAN/INN) D09950 CYP3A
Ponatinib hydrochloride (JAN/USAN) D09951 CYP3A
Posaconazole (JAN/USAN/INN) D02555 CYP3A4
Pranlukast (INN) D08408 CYP3A4
Pranlukast hydrate (JP18) D02732 CYP3A4
Praziquantel (JAN/USP/INN) D00471 CYP3A4
Prednisolone (JP18/USP/INN) D00472 CYP3A
Procainamide (INN) D08421 NAT
Procainamide hydrochloride (JP18/USP) D00477 NAT
Procaterol (INN) D08424 CYP3A4
Procaterol hydrochloride (USAN) D02404 CYP3A4
Procaterol hydrochloride hydrate (JP18) D05366 CYP3A4
Progesterone (JP18/USP/INN) D00066 CYP3A4, CYP2C19
Proguanil (INN) D08428 CYP2C19
Proguanil hydrochloride (JAN/USP) D02487 CYP2C19
Promethazine (JAN/INN) D00494 CYP2D6
Promethazine hibenzate D08768 CYP2D6
Promethazine hydrochloride (JP18/USP) D00480 CYP2D6
Promethazine maleate D08432 CYP2D6
Promethazine methylenedisalicylate (JAN) D03290 CYP2D6
Promethazine teoclate (JAN/INN) D01242 CYP2D6
Propafenone (INN) D08435 CYP2D6, CYP3A4, CYP1A2
Propafenone hydrochloride (JP18/USP) D00640 CYP2D6, CYP3A4, CYP1A2
Propiverine (INN) D08441 CYP3A4
Propiverine hydrochloride (JP18) D01007 CYP3A4
Propranolol (INN) D08443 CYP2D6, CYP1A2, CYP2C19
Propranolol hydrochloride (JP18/USP) D00483 CYP2D6, CYP1A2, CYP2C19
Proxyphylline, ephedrine hydrochloride and phenobarbital D04307 CYP3A
Quazepam (JAN/USP/INN) D00457 CYP2C9, CYP3A4
Quetiapine (INN) D08456 CYP3A4
Quetiapine fumarate (JP18/USP) D00458 CYP3A4
Quinine (BAN) D08460 CYP3A4
Quinine ascorbate (USAN) D05681 CYP3A4
Quinine dihydrochloride D08461 CYP3A4
Quinine ethylcarbonate (JP18) D01663 CYP3A4
Quinine hydrochloride hydrate (JP18) D02261 CYP3A4
Quinine sulfate (USP) D02262 CYP3A4
Quinupristin and dalfopristin D00854 CYP3A4
Quizartinib (USAN/INN) D09955 CYP3A
Quizartinib dihydrochloride (USAN) D09956 CYP3A
Rabeprazole (INN) D08463 CYP2C19, CYP3A4
Rabeprazole sodium (JP18/USP) D00724 CYP2C19, CYP3A4
Rabeprazole, amoxicillin and clarithromycin D10519 CYP2C19, CYP3A4 CYP3A4
Rabeprazole, amoxicillin and metronidazole D10520 CYP2C19, CYP3A4
Raltegravir (INN) D06676 UGT1A1
Raltegravir potassium (JAN/USAN) D07133 UGT1A1
Ramelteon (JAN/USAN/INN) D02689 CYP1A2
Ramosetron (INN) D08466 CYP1A2, CYP2D6
Ramosetron hydrochloride (JAN) D02016 CYP1A2, CYP2D6
Ranitidine (USAN/INN) D00422 CYP2D6, CYP3A
Ranitidine bismuth citrate (USAN) D05699 CYP2D6, CYP3A
Ranitidine hydrochloride (JP18/USP) D00673 CYP2D6, CYP3A
Ranolazine (USAN/INN) D05700 CYP3A CYP2D6
Ranolazine hydrochloride (USAN) D05701 CYP3A CYP2D6
Rasagiline (USAN/INN) D08469 CYP1A2
Rasagiline mesylate (USAN) D02562 CYP1A2
Rasagiline tartrate D10829 CYP1A2
Ravuconazole (prop.INN) D02556 CYP3A
Rebamipide (JP18/INN) D01121 CYP3A4
Regorafenib (USAN/INN) D10138 CYP3A4, UGT1A9
Regorafenib hydrate (JAN) D10137 CYP3A4, UGT1A9
Repaglinide (JAN/USP/INN) D00594 CYP2C8; CYP3A4
Repotrectinib (JAN/USAN) D11454 CYP3A4
Retinol acetate (JP18) D01621 CYP2C8
Retinol palmitate (JP18) D00164 CYP2C8
Retinol propionate D08477 CYP2C8
Ribociclib (USAN/INN) D10883 CYP3A4
Ribociclib succinate (USAN) D10979 CYP3A4
Rifabutin (JAN/USP/INN) D00424 CYP3A4 CYP3A
Rifampicin sodium D08479 CYP3A4, UGT
Rifampin (USP) D00211 CYP3A4, UGT
Rifapentine (USAN/INN) D00879 CYP3A4, CYP2C8, CYP2C9
Rifaximin (JAN/USAN/INN) D02554 CYP3A4 CYP3A4
Rilmazafone (INN) D08481 CES, CYP3A4
Rilmazafone hydrochloride hydrate (JP18) D01564 CES, CYP3A4
Rilpivirine (JAN/USAN/INN) D09720 CYP3A
Rilpivirine hydrochloride (JAN/USAN) D09958 CYP3A
Rilpivirine hydrochloride, tenofovir disoproxil fumarate and emtricitabine D10571 CYP3A
Riluzole (JAN/USP/INN) D00775 CYP1A2
Rimegepant (USAN/INN) D10662 CYP3A4; CYP2C9
Rimegepant sulfate (USAN) D10663 CYP3A4; CYP2C9
Riociguat (JAN/USAN/INN) D09572 CYP1A1, CYP2C8, CYP2J2, CYP3A
Risdiplam (JAN/USAN/INN) D11406 FMO1, FMO3, CYP1A1, CYP2J2, CYP3A4, CYP3A7
Risperidone (JP18/USP/INN) D00426 CYP2D6, CYP3A4
Ritlecitinib tosylate (USAN) D11970 CYP3A, CYP1A2
Ritonavir (JAN/USP/INN) D00427 CYP3A, CYP2D6 CYP3A CYP1A2, CYP2C9, CYP2C19
Rivaroxaban (JAN/USAN/INN) D07086 CYP3A4, CYP2J2
Roflumilast (JAN/USAN/INN) D05744 CYP3A4, CYP1A2
Rolapitant (USAN/INN) D10742 CYP3A4 CYP2D6
Rolapitant hydrochloride (USAN) D08988 CYP3A4 CYP2D6
Romidepsin (JAN/USAN/INN) D06637 CYP3A
Ropinirole (USAN/INN) D08489 CYP1A2
Ropinirole hydrochloride (JAN/USP) D00784 CYP1A2
Ropivacaine (INN) D08490 CYP1A2, CYP3A4
Ropivacaine hydrochloride (USP) D04048 CYP1A2, CYP3A4
Roxadustat (JAN/USAN/INN) D10593 CYP2C8, UGT1A9
Roxithromycin (JP18/USAN/INN) D01710 CYP3A
Rufinamide (JAN/USP/INN) D05775 CES
Rupatadine (INN) D07407 CYP3A4
Rupatadine fumarate (JAN) D08497 CYP3A4
Ruxolitinib (USAN/INN) D09959 CYP3A4; CYP2C9
Ruxolitinib phosphate (JAN/USAN) D09960 CYP3A4; CYP2C9
Safinamide (USAN/INN) D10158 MAOA; CYP3A4
Safinamide mesylate (USAN) D10191 MAOA; CYP3A4
Salmeterol (USAN/INN) D05792 CYP3A4
Salmeterol xinafoate (JAN/USP) D00687 CYP3A4
Salmeterol xinafoate and fluticasone propionate D08699 CYP3A4
Saquinavir (JAN/USP/INN) D00429 CYP3A4
Saquinavir mesylate (USP) D01160 CYP3A4
Sarpogrelate (INN) D08508 CYP1A2, CYP2B6, CYP2C9, CYP2C19, CYP2D6, CYP3A4
Sarpogrelate hydrochloride (JP18) D01624 CYP1A2, CYP2B6, CYP2C9, CYP2C19, CYP2D6, CYP3A4
Saxagliptin (USAN/INN) D08996 CYP3A4, CYP3A5
Saxagliptin hydrate (JAN) D09753 CYP3A4, CYP3A5
Saxagliptin hydrochloride D10262 CYP3A4, CYP3A5
Selegiline (USAN/INN) D03731 CYP2B6, CYP2D6, CYP3A4; CYP2A6
Selegiline hydrochloride (JAN/USP) D00785 CYP2B6, CYP2D6, CYP3A4; CYP2A6
Selexipag (JAN/USAN/INN) D09994 CYP2C8, CYP3A4, UGT1A3, UGT2B7
Selinexor (USAN/INN) D11222 CYP3A4, UGT, GST
Selpercatinib (JAN/USAN/INN) D11713 CYP3A4
Selumetinib (USAN/INN) D09666 CYP3A4, UGT1A1, UGT1A3; CYP2C19, CYP1A2, CYP2C9, CYP2E1, CYP3A5
Selumetinib sulfate (JAN/USAN) D10024 CYP3A4, UGT1A1, UGT1A3; CYP2C19, CYP1A2, CYP2C9, CYP2E1, CYP3A5
Sertraline (INN) D02360 CYP2C19, CYP2C9, CYP2B6, CYP3A4
Sertraline hydrochloride (JAN/USP) D00825 CYP2C19, CYP2C9, CYP2B6, CYP3A4
Sildenafil (INN) D08514 CYP3A4; CYP2C9
Sildenafil citrate (JAN/USP) D02229 CYP3A4; CYP2C9
Silodosin (JP18/INN) D01965 CYP3A4, UGT
Simeprevir (JAN/USAN) D10081 CYP3A CYP3A
Simeprevir sodium (JAN) D10469 CYP3A CYP3A
Simvastatin (JP18/USP/INN) D00434 CYP3A4
Siponimod (USAN/INN) D11460 CYP2C9; CYP3A4
Siponimod fumarate (USAN) D11072 CYP2C9; CYP3A4
Sirolimus (JAN/USAN/INN) D00753 CYP3A4 CYP3A4
Sitagliptin and ipragliflozin D11064 UGT2B7
Sofosbuvir and velpatasvir D10827 CYP2B6, CYP2C8, CYP3A4
Solifenacin (INN) D08522 CYP3A4
Solifenacin succinate (JAN/USAN/INN) D01269 CYP3A4
Somatropin (USP/INN) D02691 CYP2C19
Sonidegib (USAN/INN) D10119 CYP3A
Sonidegib phosphate (USAN) D10729 CYP3A
Sotagliflozin (USAN/INN) D10669 UGT1A9; CYP3A4
Sotorasib (JAN/USAN) D12055 CYP3A
Sparsentan (USAN/INN) D11776 CYP3A
Sparteine (INN) D01041 CYP2D6
Sparteine sulfate (JAN/USAN) D02239 CYP2D6
Stiripentol (JAN/USAN/INN) D05928 CYP1A2, CYP2C19, CYP3A4 CYP1A2, CYP3A4, CYP2D6, CYP2C19, CYP2C9
Sumatriptan (JAN/USP/INN) D00451 MAOA
Sumatriptan succinate (JAN/USP) D00676 MAOA
Sunitinib (INN) D08552 CYP3A4
Sunitinib malate (JAN/USAN) D06402 CYP3A4
Suprofen (JAN/USP/INN) D00452 CYP2C9
Suvorexant (JAN/USAN) D10082 CYP3A; CYP2C19
Synthetic conjugated estrogens, B (USAN) D05987 CYP3A4
Tacrine (INN) D08555 CYP1A2
Tacrine hydrochloride (USP) D02068 CYP1A2
Tacrolimus (INN) D08556 CYP3A4
Tacrolimus (USP/INN) D00107 CYP3A4
Tadalafil (JAN/USP/INN) D02008 CYP3A4
Tamibarotene (JAN/USAN/INN) D01418 CYP3A4
Tamoxifen (INN) D08559 CYP2D6, CYP3A4
Tamoxifen citrate (JP18/USP) D00966 CYP2D6, CYP3A4
Tapentadol (USAN/INN) D06007 UGT
Tapentadol hydrochloride (JAN) D10199 UGT
Tasimelteon (USAN/INN) D09388 CYP3A4, CYP1A2
Tecovirimat (USAN/INN) D09390 UGT1A1, UGT1A4
Tecovirimat hydrate (JAN) D11557 UGT1A1, UGT1A4
Tegafur (JP18/USAN/INN) D01244 CYP2A6
Tegaserod (USAN/INN) D06056 UGT
Tegaserod maleate (USAN) D02730 UGT
Telaprevir (JAN/USAN/INN) D09012 CYP3A4 CYP3A4, CYP3A5
Telithromycin (JAN/USAN/INN) D01078 CYP3A, CYP2D6 CYP3A, CYP2D6
Telmisartan (JP18/USP/INN) D00627 UGT
Telmisartan and amlodipine besilate (JP18) D09743 CYP3A4, UGT
Telmisartan and hydrochlorothiazide (JP18) D09219 UGT
Telmisartan, amlodipine and hydrochlorothiazide D10805 CYP3A4, UGT
Temsavir (USAN/INN) D10734 CYP3A
Temsirolimus (JAN/USAN/INN) D06068 CYP3A4
Tenapanor (USAN/INN) D11652 CYP3A4, CYP3A5
Tenapanor hydrochloride (JAN/USAN) D11653 CYP3A4, CYP3A5
Teneligliptin (INN) D08616 CYP3A4, FMO1, FMO3 CYP2D6, CYP3A4, FMO
Teneligliptin and canagliflozin D10897 CYP3A4, FMO1, FMO3, UGT1A9, UGT2B4
Teneligliptin hydrobromide (JAN) D11968 CYP3A4, FMO1, FMO3 CYP2D6, CYP3A4, FMO
Teneligliptin hydrobromide hydrate (JAN) D09756 CYP3A4, FMO1, FMO3 CYP2D6, CYP3A4, FMO
Tenoxicam (JAN/USAN/INN) D01767 CYP2C9
Tepotinib (USAN/INN) D11717 CYP3A4, CYP2C8
Tepotinib hydrochloride (USAN) D11073 CYP3A4, CYP2C8
Terbinafine (USAN/INN) D02375 CYP2C9, CYP1A2, CYP3A4, CYP2C8, CYP2C19 CYP2D6
Terbinafine hydrochloride (JP18/USP) D02219 CYP2C9, CYP1A2, CYP3A4, CYP2C8, CYP2C19 CYP2D6
Terfenadine (JAN/USAN/INN) D00521 CYP3A
Tetrabenazine (JAN/INN) D08575 CYP2D6; CYP3A4, CYP1A2, CBR
Theophylline (JP18) D00371 CYP1A2
Theophylline (USP) D06103 CYP1A2
Theophylline sodium acetate (JAN) D01712 CYP1A2
Theophylline sodium glycinate (USP) D06104 CYP1A2
Ticagrelor (JAN/USAN/INN) D09017 CYP3A CYP3A
Ticlopidine (INN) D08594 CYP2C19, CYP1A2, CYP2B6, CYP2D6
Ticlopidine hydrochloride (JP18/USP) D01028 CYP2C19, CYP1A2, CYP2B6, CYP2D6
Timolol (INN) D08600 CYP2D6
Timolol (USAN) D00378 CYP2D6
Timolol maleate (JP18/USP) D00603 CYP2D6
Tiotropium and olodaterol D10744 UGT
Tivozanib (USAN/INN) D09683 CYP3A4
Tivozanib hydrochloride (USAN) D10190 CYP3A4
Tizanidine (INN) D08611 CYP1A2
Tizanidine hydrochloride (JP18/USP) D00776 CYP1A2
Tofacitinib (USAN) D09970 CYP3A4; CYP2C19
Tofacitinib citrate (JAN/USAN) D09783 CYP3A4; CYP2C19
Tofogliflozin (USAN) D09978 CYP2C18, CYP4A11, CYP4F3
Tolcapone (JAN/USP/INN) D00786 COMT
Tolterodine (USAN/INN) D00646 CYP2D6, CYP3A4
Tolterodine tartrate (JAN/USP) D01148 CYP2D6, CYP3A4
Tolvaptan (JAN/USAN/INN) D01213 CYP3A4
Topiramate (JAN/USP/INN) D00537 CYP3A4
Torasemide sodium D08619 CYP2C9, CYP2C8
Toremifene (INN) D08620 CYP3A4
Toremifene citrate (JAN/USAN) D00967 CYP3A4
Torsemide (USP) D00382 CYP2C9, CYP2C8
Trabectedin (JAN/USAN/INN) D06199 CYP3A4
Tramadol (INN) D08623 CYP2D6, CYP3A4
Tramadol hydrochloride (JP18/USP) D01355 CYP2D6, CYP3A4
Tramadol hydrochloride and acetaminophen D09999 CYP2D6, CYP3A4
Tranilast (JP18/USAN/INN) D02027 CYP2C9
Trazodone (INN) D08626 CYP3A4, CYP2D6
Trazodone hydrochloride (JAN/USP) D00820 CYP3A4, CYP2D6
Trelagliptin (USAN) D10178 CYP2D6
Trelagliptin succinate (JAN/USAN) D10179 CYP2D6
Treprostinil (JAN/USAN/INN) D06213 CYP2C8
Treprostinil diolamine (USAN) D10430 CYP2C8
Treprostinil monosodium salt D08628 CYP2C8
Treprostinil palmitil (USAN/INN) D12005 CYP2C8
Treprostinil phosphate (USAN) D12629 CYP2C8
Triazolam (JP18/USP/INN) D00387 CYP3A4
Trimethoprim (JAN/USP/INN) D00145 CYP2C8
Trimethoprim hydrochloride D11085 CYP2C8
Trimethoprim lactate D08644 CYP2C8
Trimethoprim sulfate (USP) D06236 CYP2C8
Tripelennamine (INN) D08645 CYP2D6
Tripelennamine citrate D06246 CYP2D6
Tripelennamine hydrochloride (USP) D02091 CYP2D6
Troglitazone (JAN/USAN/INN) D00395 CYP3A
Troleandomycin (USAN/INN) D01322 CYP3A4 CYP3A4
Tucatinib (USAN/INN) D11141 CYP2C8; CYP3A
Tucatinib ethanolate (JAN) D12442 CYP2C8; CYP3A
Ubrogepant (USAN/INN) D10673 CYP3A4
Umeclidinium (USAN) D10180 CYP2D6
Umeclidinium bromide (JAN/USAN) D10181 CYP2D6
Umeclidinium bromide and vilanterol D10533 CYP2D6, CYP3A4
Upadacitinib (USAN/INN) D10994 CYP3A4; CYP2D6
Upadacitinib hydrate (JAN) D11048 CYP3A4; CYP2D6
Upadacitinib tartrate (USAN) D10995 CYP3A4; CYP2D6
Urapidil (JP18/INN) D01333 CYP2D6
Urapidil hydrochloride D08662 CYP2D6
Valbenazine (USAN/INN) D10675 CYP3A4, CYP3A5; CYP2D6
Valbenazine tosylate (USAN) D10999 CYP3A4, CYP3A5; CYP2D6
Valsartan (JP18/USP/INN) D00400 CYP2C9
Valsartan and amlodipine besilate D09745 CYP3A4
Valsartan and cilnidipine D10525 CYP3A4; CYP2C19
Vamorolone (USAN/INN) D11000 CYP3A4, CYP3A5, CYP2C8, UGT1A3, UGT2B7, UGT2B17
Vandetanib (JAN/USAN/INN) D06407 CYP3A4
Vaniprevir (JAN/USAN/INN) D09987 CYP3A
Vardenafil (USAN/INN) D08668 CYP3A4
Vardenafil dihydrochoride (USAN) D02731 CYP3A4
Vardenafil hydrochloride (USP) D09989 CYP3A4
Vardenafil hydrochloride hydrate (JAN) D03260 CYP3A4
Vemurafenib (JAN/USAN/INN) D09996 CYP1A2, CYP2C9 CYP3A4
Venlafaxine (INN) D08670 CYP2D6; CYP3A4
Venlafaxine besylate monohydrate D12403 CYP2D6; CYP3A4
Venlafaxine hydrochloride (JAN/USP) D00821 CYP2D6; CYP3A4
Verapamil (USAN/INN) D02356 CYP3A4
Verapamil hydrochloride (JP18/USP) D00619 CYP3A4
Vericiguat (JAN/USAN/INN) D11051 UGT1A9; UGT1A1
Vibegron (JAN/USAN/INN) D10433 CYP3A4
Vilazodone (USAN/INN) D09698 CYP3A4; CYP2D6, CYP2C19
Vilazodone hydrochloride (USAN) D09699 CYP3A4; CYP2D6, CYP2C19
Viloxazine (INN) D08673 CYP2D6, UGT1A9, UGT2B15
Viloxazine hydrochloride (USAN) D02572 CYP2D6, UGT1A9, UGT2B15
Vinblastine (INN) D08675 CYP3A4
Vinblastine sulfate (JP18/USP) D01068 CYP3A4
Vincristine (INN) D08679 CYP3A
Vincristine sulfate (JP18/USP) D02197 CYP3A
Vindesine (USAN/INN) D06304 CYP3A
Vindesine sulfate (JAN/USAN) D01769 CYP3A
Vinorelbine (INN) D08680 CYP3A4
Vinorelbine tartrate (USP) D01935 CYP3A4
Vitamin A (USP) D06543 CYP2C8
Vitamin A oil (JP18) D00069 CYP2C8
Voclosporin (JAN/USAN/INN) D09033 CYP3A4
Vonoprazan (USAN/INN) D11784 CYP3A4; CYP2B6, CYP2C19, CYP2D6
Vonoprazan and amoxicillin D12756 CYP3A4, CYP3A5, CYP2B6, CYP2C19, CYP2C9, CYP2D6
Vonoprazan fumarate (JAN/USAN) D10466 CYP3A4; CYP2B6, CYP2C19, CYP2D6
Vonoprazan, amoxicillin and clarithromycin D10775 CYP3A4; CYP2B6, CYP2C19, CYP2D6 CYP3A4
Vonoprazan, amoxicillin and metronidazole D10774 CYP3A4; CYP2B6, CYP2C19, CYP2D6
Vorapaxar (USAN/INN) D09765 CYP3A4, CYP2J2
Vorapaxar sulfate (JAN/USAN) D09766 CYP3A4, CYP2J2
Voriconazole (JP18/USP/INN) D00578 CYP3A
Vorinostat (JAN/USAN) D06320 UGT
Vortioxetine (USAN) D10184 CYP2D6; CYP3A4, CYP3A5, CYP2C19, CYP2C9, CYP2A6, CYP2C8, CYP2B6
Vortioxetine hemihydrobromide (USAN) D12544 CYP2D6; CYP3A4, CYP3A5, CYP2C19, CYP2C9, CYP2A6, CYP2C8, CYP2B6
Vortioxetine hydrobromide (JAN/USAN) D10185 CYP2D6; CYP3A4, CYP3A5, CYP2C19, CYP2C9, CYP2A6, CYP2C8, CYP2B6
Voxelotor (USAN) D11330 CYP3A4; CYP2C19, CYP2B6, CYP2C9
Warfarin (INN) D08682 CYP2C9
Warfarin potassium (JP18) D01280 CYP2C9
Warfarin sodium (USP) D00564 CYP2C9
Zaleplon (JAN/USP/INN) D00530 AOX1, CYP3A4
Zanubrutinib (JAN/USAN/INN) D11422 CYP3A
Zilucoplan (USAN/INN) D12357 CYP4F2
Zilucoplan sodium (JAN) D12356 CYP4F2
Zolmitriptan (JAN/USP/INN) D00415 CYP1A2, MAOA
Zolpidem (INN) D08690 CYP3A4; CYP2C9, CYP1A2
Zolpidem tartrate (JP18/USP) D00706 CYP3A4; CYP2C9, CYP1A2
Zonisamide (JP18/USP/INN) D00538 CYP3A
Zopiclone (JP18/INN) D01372 CYP3A4; CYP2C8
Zuclopenthixol (INN) D03556 CYP2D6
Zuclopenthixol acetate D08691 CYP2D6
Zuclopenthixol decanoate D08692 CYP2D6
Zuclopenthixol dihydrochloride D08693 CYP2D6
Zuranolone (JAN/USAN/INN) D11793 CYP3A4
dl-Methylephedrine hydrochloride, dihydrocodeine phosphate, diprophylline, diphenhydramine salicylate, acetaminophen and bromovalerylurea D08695 UGT2B7, UGT2B4; CYP3A4, CYP2D6
l-Isoprenaline hydrochloride (JP18) D02150 COMT

Drug transporters

Drug KEGG Substrate Inhibitor Inducer
Acyclovir (USP) D00222 SLC22A1, SLC22A6, SLC22A8
Acyclovir sodium (USAN) D02764 SLC22A1, SLC22A6, SLC22A8
Afatinib (USAN/INN) D09724 ABCB1
Afatinib dimaleate (USAN) D09733 ABCB1
Aliskiren (USAN/INN) D03208 ABCB1
Aliskiren fumarate (JAN/USAN) D06412 ABCB1
Amantadine (INN) D07441 SLC22A2
Amantadine hydrochloride (JP18/USP) D00777 SLC22A2
Aminohippurate sodium (USP) D01421 SLC22A6
Aminohippuric acid (USP) D06890 SLC22A6
Amoxicillin hydrate, clarithromycin and lansoprazole D08774 ABCB1
Apalutamide (JAN/INN) D11040 ABCB1, ABCG2, SLCO1B1
Apixaban (JAN/USAN/INN) D03213 ABCB1, ABCG2
Asunaprevir (JAN/USAN) D10093 ABCB1, SLCO1B1 SLCO1B1, SLCO1B3, ABCB1
Atazanavir and cobicistat D10753 ABCB1, ABCG2, SLCO1B1, SLCO1B3
Atorvastatin (INN) D07474 ABCB1, ABCG2, SLCO1B1, SLCO1B3
Atorvastatin calcium (USP) D02258 ABCB1, ABCG2, SLCO1B1, SLCO1B3
Atorvastatin calcium anhydorous D00887 ABCB1, ABCG2, SLCO1B1, SLCO1B3
Atorvastatin calcium propylene glycol solvate D11095 ABCB1, ABCG2, SLCO1B1, SLCO1B3
Azithromycin (INN) D07486 ABCB1 ABCB1
Azithromycin (USP) D06390 ABCB1 ABCB1
Azithromycin hydrate (JP18) D02134 ABCB1 ABCB1
Baricitinib (JAN/USAN/INN) D10308 ABCB1, ABCG2, SLC22A8, SLC47A2
Benzylpenicillin (INN) D02336 SLC22A8
Berotralstat (USAN/INN) D11673 ABCB1, ABCG2
Berotralstat hydrochloride (JAN/USAN) D11674 ABCB1, ABCG2
Berythromycin (USAN/INN) D03098 ABCB1
Betamipron (JP18/INN) D01331 SLC22A8, SLC22A6
Bumetanide (JP18/USP/INN) D00247 SLC22A8
Canagliflozin (USAN/INN) D09592 ABCB1 ABCB1
Cannabidiol (USAN/INN) D10915 ABCB1
Carbamazepine (JP18/USP/INN) D00252 ABCB1
Carotegrast methyl (JAN) D09799 SLCO1B1, SLCO1B3
Carvedilol (JP18/USP/INN) D00255 ABCB1
Carvedilol phosphate (USAN) D03415 ABCB1
Ceftizoxime (INN) D07658 SLC22A8
Ceftizoxime sodium (JP18/USP) D00923 SLC22A8
Cetirizine (INN) D07662 ABCB1, SLC22A2 SLC22A2
Cetirizine hydrochloride (JP18/USP) D00664 ABCB1, SLC22A2 SLC22A2
Cisplatin (JP18/USP/INN) D00275 SLC22A2
Citalopram (USP/INN) D07704 ABCB1
Citalopram hydrobromide (USP) D00822 ABCB1
Citalopram hydrochloride D07705 ABCB1
Clarithromycin (JP18/USP/INN) D00276 ABCB1
Clarithromycin lactobionate D07710 ABCB1
Co-Trimoxazole (BAN) D00285 SLC22A2
Colchicine (JP18/USP) D00570 ABCB1
Crizotinib (JAN/USAN/INN) D09731 ABCB1, SLC22A1, SLC22A2
Cyclosporine (USP) D00184 ABCB1
Dabigatran (USAN/INN) D09707 ABCB1
Dabigatran etexilate (USAN/INN) D07144 ABCB1
Dabigatran etexilate mesylate (USAN) D07082 ABCB1
Daclatasvir (USAN) D10065 ABCB1
Daclatasvir dihydrochloride (USAN) D10105 ABCB1
Daclatasvir, asunaprevir and beclabuvir D10882 ABCB1, ABCG2, SLCO1B1 ABCB1, ABCG2, SLCO1B1, SLCO1B3
Dasabuvir, ombitasvir, paritaprevir and ritonavir D10582 SLCO1B1, SLCO1B3, ABCB1, ABCG2 SLCO1B1, SLCO1B3, ABCG2
Deflazacort (USAN/INN) D03671 ABCB1
Diclofenac (USAN/INN) D07816 SLC22A8
Diclofenac calcium D07819 SLC22A8
Diclofenac diethylamine D07817 SLC22A8
Diclofenac epolamine D07818 SLC22A8
Diclofenac potassium (USP) D00903 SLC22A8
Diclofenac sodium (JP18/USP) D00904 SLC22A8
Digitoxin (JAN/USP/INN) D00297 ABCB1
Digoxin (JP18/USP) D00298 ABCB1
Dolutegravir (USAN) D10066 SLC22A2, SLC47A1
Dolutegravir sodium (JAN/USAN) D10113 SLC22A2, SLC47A1
Dolutegravir sodium and rilpivirine hydrochloride D11282 SLC22A2, SLC47A1
Dolutegravir, abacavir and lamivudine D10600 SLC22A2, SLC47A1
Dopamine (INN) D07870 SLC22A2
Dopamine hydrochloride (JP18/USP) D00633 SLC22A2
Dronedarone (INN) D02537 ABCB1
Dronedarone hydrochloride (USP) D03914 ABCB1
Edoxaban (USAN/INN) D09710 ABCB1
Edoxaban tosilate hydrate (JAN) D09546 ABCB1
Edoxaban tosylate (USAN) D11568 ABCB1
Elbasvir (JAN/USAN/INN) D10625 ABCB1 ABCG2, ABCB1
Eliglustat (USAN/INN) D09893 ABCB1
Eliglustat tartrate (JAN/USAN) D09894 ABCB1
Elobixibat (USAN/INN) D10796 ABCB1
Elobixibat hydrate (JAN) D10795 ABCB1
Elvitegravir, cobicistat, emtricitabine and tenofovir disoproxil D10756 ABCB1
Empagliflozin (JAN/USAN/INN) D10459 ABCB1, ABCG2
Empagliflozin and linagliptin D10588 ABCB1, ABCG2
Emtricitabine (JAN/USAN/INN) D01199 SLC22A8
Emtricitabine and tenofovir alafenamide D10835 ABCB1
Emtricitabine, rilpivirine and tenofovir alafenamide D10836 ABCB1
Ensitrelvir (USAN/INN) D12619 ABCB1, ABCG2, SLCO1B1, SLCO1B3
Ensitrelvir fumarate (USAN) D12353 ABCB1, ABCG2, SLCO1B1, SLCO1B3
Erdafitinib (JAN/USAN/INN) D10927 ABCB1 ABCB1, SLC22A2
Erythromycin (JP18/USP/INN) D00140 ABCB1
Erythromycin acistrate (USAN) D02523 ABCB1
Erythromycin estolate (USP) D00851 ABCB1
Erythromycin ethylsuccinate (JP18/USP) D01361 ABCB1
Erythromycin gluceptate (USP) D02524 ABCB1
Erythromycin lactobionate (JP18/USP) D02009 ABCB1
Erythromycin propionate (USAN) D02525 ABCB1
Erythromycin salnacedin (USAN) D04054 ABCB1
Erythromycin stearate (JP18/USP) D02184 ABCB1
Erythromycin stinoprate (INN) D07910 ABCB1
Erythromycin thiocyanate D07909 ABCB1
Estrogens, conjugated (JAN/USP) D04070 ABCB11
Etravirine (JAN/USAN/INN) D04112 ABCB1
Everolimus (JAN/USAN/INN) D02714 ABCB1
Ezetimibe (JAN/USP/INN) D01966 SLCO1B1, MRP2
Ezetimibe and rosuvastatin D11520 SLCO1B1, ABCG2
Ezetimibe and simvastatin D10257 SLCO1B1
Ezogabine (USAN) D09569 SLC22A8, ABCB1
Famotidine (JP18/USP/INN) D00318 SLC22A2, SLC22A8 SLC22A2, SLC22A3
Fidaxomicin (JAN/USAN) D09394 ABCB1
Fluoxetine (USAN/INN) D00326 ABCB1
Fluoxetine hydrochloride (JAN/USP) D00823 ABCB1
Fluvastatin (INN) D07983 SLCO1B1 ABCB11
Fluvastatin sodium (JAN/USP) D00892 SLCO1B1 ABCB11
Fosphenytoin (INN) D07993 ABCB1
Fosphenytoin sodium (USP) D02096 ABCB1
Fosphenytoin sodium hydrate (JAN) D07595 ABCB1
Fostamatinib (USAN) D09347 ABCB1, ABCG2
Fostamatinib disodium (USAN) D09348 ABCB1, ABCG2
Fostemsavir (USAN) D10707 ABCB1, ABCG2 ABCG2, SLCO1B1, SLCO1B3
Fostemsavir tromethamine (USAN) D10708 ABCB1, ABCG2 ABCG2, SLCO1B1, SLCO1B3
Furosemide (JP18/USP/INN) D00331 SLC22A6, SLC22A8, ABCC4
Furosemide diolamine D08001 SLC22A6, SLC22A8, ABCC4
Gemfibrozil (JAN/USP/INN) D00334 SLCO1B1
Gilteritinib (USAN/INN) D10709 ABCB1
Gilteritinib fumarate (JAN/USAN) D10800 ABCB1
Glecaprevir and pibrentasvir D11014 ABCB1, ABCG2, SLCO1B1, SLCO1B3 ABCB1, ABCG2, SLCO1B1, SLCO1B3
Glycopyrronium bromide and indacaterol maleate D10505 ABCB1
Grazoprevir (USAN) D10639 ABCB1, SLCO1B1 ABCG2
Grazoprevir (USAN/INN) D11565 ABCB1, SLCO1B1 ABCG2
Indacaterol (USAN/INN) D09318 ABCB1
Indacaterol acetate (JAN) D11009 ABCB1
Indacaterol maleate (JAN/USAN) D09319 ABCB1
Isavuconazonium (USAN) D10644 ABCB1, SLC22A2, SLC47A1
Isavuconazonium sulfate (JAN/USAN) D10643 ABCB1, SLC22A2, SLC47A1
Istradefylline (JAN/USAN/INN) D04641 ABCB1
Itraconazole (JP18/USP) D00350 ABCB1
Ivermectin (JAN/USP/INN) D00804 ABCB1
Ketoconazole (JP18/USP) D00351 ABCB1
Ketoprofen (JP18/USP/INN) D00132 SLC22A7
Ketoprofen lysine D08102 SLC22A7
Ketoprofen sodium D08103 SLC22A7
Lamivudine (JAN/USP/INN) D00353 SLC22A6
Lamivudine, nevirapine and zidovudine D11521 SLC22A2, SLC47A1, SLC47A2
Lansoprazole (JP18/USP/INN) D00355 ABCC2
Lapatinib (INN) D08108 ABCB1, ABCG2
Lapatinib ditosylate (USAN) D04024 ABCB1, ABCG2
Ledipasvir and sofosbuvir D10578 ABCB1, ABCG2
Lenacapavir (USAN/INN) D12161 ABCB1
Lenacapavir sodium (JAN/USAN) D12162 ABCB1
Lenvatinib (USAN/INN) D09919 ABCB1
Lenvatinib mesylate (USAN) D09920 ABCB1
Letermovir (JAN/USAN/INN) D10801 SLCO1B1, SLCO1B3 ABCG2, SLCO1B1, SLCO1B3
Levofloxacin (INN) D08120 SLCO1A2
Levofloxacin (USP) D00588 SLCO1A2
Linagliptin and metformin hydrochloride D10264 ABCB1
Loperamide (INN) D08144 ABCB1
Loperamide hydrochloride (JAN/USP) D00729 ABCB1
Loperamide oxide (INN) D07113 ABCB1
Lorlatinib (JAN/USAN/INN) D11012 ABCB1
Memantine (INN) D08174 SLC22A2
Memantine hydrochloride (JAN/USP) D04905 SLC22A2
Methadone (BAN) D08195 ABCB1
Methadone hydrochloride (JAN/USP) D02102 ABCB1
Metildigoxin (INN) D09847 ABCB1
Metildigoxin (JP18) D02587 ABCB1
Mirabegron (JAN/USAN/INN) D09535 ABCB1
Mitoxantrone (INN) D08224 ABCG2, ABCC2
Mitoxantrone hydrochloride (JAN/USP) D02166 ABCG2, ABCC2
Nilotinib (USAN/INN) D08953 ABCB1
Nilotinib hydrochloride dihydrate (JAN) D12444 ABCB1
Nilotinib hydrochloride hydrate (JAN) D06413 ABCB1
Nintedanib (USAN/INN) D10481 ABCB1
Nintedanib esylate (USAN) D10396 ABCB1
Novobiocin sodium (JAN/USP) D01209 SLC22A6, SLC22A8
Odevixibat (USAN) D11716 ABCB1
Olmesartan (USAN/INN) D05246 ABCC2, ABCB1, ABCG2
Olmesartan medoxomil (JP18/USP) D01204 ABCC2, ABCB1, ABCG2
Ombitasvir, paritaprevir and ritonavir D10745 ABCB1, SLCO1B1, SLCO1B3, ABCG2 ABCB1, SLCO1B1, SLCO1B3, ABCG2
Omeprazole, clarithromycin and amoxicillin D10246 ABCB1
Osimertinib mesylate (USAN) D10766 ABCG2
Oxaliplatin (JAN/USP/INN) D01790 SLC22A2, SLC22A1
Pemafibrate (JAN) D10711 SLCO1B1, SLCO1B3
Penicillin G potassium (USP) D01053 SLC22A8
Penicillin G sodium (USP) D05408 SLC22A8
Phenytoin (JP18/USP/INN) D00512 ABCB1
Phenytoin and phenobarbital D07583 ABCB1
Phenytoin sodium (USP) D02103 ABCB1
Pimitespib (JAN) D11920 SLC47A1, SLC47A2
Pindolol (JP18/USP/INN) D00513 SLC22A2
Posaconazole (JAN/USAN/INN) D02555 ABCB1
Pravastatin (INN) D08410 ABCC2, SLCO1B1, SLCO2B1
Pravastatin sodium (JP18/USP) D00893 ABCC2, SLCO1B1, SLCO2B1
Prazosin (INN) D08411 SLC22A3
Prazosin hydrochloride (JP18/USP) D00609 SLC22A3
Procainamide (INN) D08421 SLC22A1, SLC22A2, SLC47A1, SLC47A2
Procainamide hydrochloride (JP18/USP) D00477 SLC22A1, SLC22A2, SLC47A1, SLC47A2
Quinine (BAN) D08460 ABCB1
Quinine ascorbate (USAN) D05681 ABCB1
Quinine dihydrochloride D08461 ABCB1
Quinine ethylcarbonate (JP18) D01663 ABCB1
Quinine hydrochloride hydrate (JP18) D02261 ABCB1
Quinine sulfate (USP) D02262 ABCB1
Rabeprazole, amoxicillin and clarithromycin D10519 ABCB1
Ranitidine (USAN/INN) D00422 SLC22A2 SLC22A2
Ranitidine bismuth citrate (USAN) D05699 SLC22A2 SLC22A2
Ranitidine hydrochloride (JP18/USP) D00673 SLC22A2 SLC22A2
Ranolazine (USAN/INN) D05700 ABCB1
Ranolazine hydrochloride (USAN) D05701 ABCB1
Regorafenib (USAN/INN) D10138 ABCB1, ABCG2
Regorafenib hydrate (JAN) D10137 ABCB1, ABCG2
Relugolix (JAN/USAN/INN) D10888 ABCB1
Remdesivir (JAN/USAN) D11472 SLCO1B1, SLCO1B3
Reserpine (JP18/USP/INN) D00197 ABCC2
Rifampicin sodium D08479 SLCO1B1, SLCO1B3 ABCB1
Rifampin (USP) D00211 SLCO1B1, SLCO1B3 ABCB1
Riociguat (JAN/USAN/INN) D09572 ABCB1, ABCG2
Rivaroxaban (JAN/USAN/INN) D07086 ABCB1, ABCG2
Rosuvastatin (INN) D08492 SLCO1B1, ABCG2
Rosuvastatin calcium (JP18/USP) D01915 SLCO1B1, ABCG2
Roxadustat (JAN/USAN/INN) D10593 ABCG2, SLCO1B1, SLC22A6, SLC22A8 ABCG2, SLCO1B1
Salicylic acid (JP18/USP) D00097 SLC22A7
Saquinavir (JAN/USP/INN) D00429 ABCB1
Saquinavir mesylate (USP) D01160 ABCB1
Simeprevir (JAN/USAN) D10081 ABCB1, SLCO1B1 ABCB1, SLCO1B1, ABCG2
Simeprevir sodium (JAN) D10469 ABCB1, SLCO1B1 ABCB1, SLCO1B1, ABCG2
Simvastatin (JP18/USP/INN) D00434 SLCO1B1
Sirolimus (JAN/USAN/INN) D00753 ABCB1
Sodium furosemide D07999 SLC22A6, SLC22A8, ABCC4
Sofosbuvir (JAN/USAN/INN) D10366 ABCB1, ABCG2
Sofosbuvir and velpatasvir D10827 ABCB1, ABCG2 ABCB1, ABCG2, SLCO1B1, SLCO1B3
Sulfasalazine (USP/INN) D00448 ABCG2
Sulfobromophthalein sodium (JP18) D02210 SLCO1B1, SLCO1B3, SLCO1A2, SLCO2B1
Sulphobromophthalein (BAN) D08548 SLCO1B1, SLCO1B3, SLCO1A2, SLCO2B1
Suvorexant (JAN/USAN) D10082 ABCB1
Synthetic conjugated estrogens, B (USAN) D05987 ABCB11
Tazemetostat (USAN/INN) D11444 ABCB1 SLC47A1, SLC47A2
Tazemetostat hydrobromide (JAN/USAN) D11485 ABCB1 SLC47A1, SLC47A2
Telaprevir (JAN/USAN/INN) D09012 ABCB1, SLCO1B1
Temsavir (USAN/INN) D10734 ABCB1, ABCG2 ABCG2, SLCO1B1, SLCO1B3
Teneligliptin and canagliflozin D10897 ABCB1 ABCB1
Tenofovir alafenamide (USAN/INN) D10428 ABCB1, ABCG2
Tenofovir alafenamide fumarate (JAN/USAN) D10605 ABCB1, ABCG2
Ticagrelor (JAN/USAN/INN) D09017 ABCB1 ABCB1
Tolvaptan (JAN/USAN/INN) D01213 ABCB1 ABCB1
Topotecan (BAN) D08618 ABCB1, ABCG2, ABCC4
Topotecan hydrochloride (USAN) D02168 ABCB1, ABCG2, ABCC4
Valsartan (JP18/USP/INN) D00400 SLCO1B1, SLCO1B3, ABCC2
Vandetanib (JAN/USAN/INN) D06407 SLC22A2, ABCB1
Vaniprevir (JAN/USAN/INN) D09987 SLCO1B1, SLCO1B3
Vemurafenib (JAN/USAN/INN) D09996 ABCB1
Verapamil (USAN/INN) D02356 ABCB1 ABCB1
Verapamil hydrochloride (JP18/USP) D00619 ABCB1 ABCB1
Vibegron (JAN/USAN/INN) D10433 ABCB1
Vonoprazan, amoxicillin and clarithromycin D10775 ABCB1
Zalcitabine (JAN/USP/INN) D00412 SLC22A6
Zidovudine (JP18/USP/INN) D00413 SLC22A6, SLC22A8

Last updated: January 30, 2024