| Drug |
KEGG |
Substrate |
Inhibitor |
Inducer |
| Abametapir (USAN/INN) |
D10687 |
CYP1A2 |
|
|
| Abemaciclib (JAN/USAN/INN) |
D10688 |
CYP3A |
|
|
| Abiraterone acetate (JAN/USP) |
D09701 |
CYP3A4 |
|
|
| Abrocitinib (JAN/USAN) |
D11400 |
CYP2C19, CYP2C9 |
|
|
| Acalabrutinib (JAN/USAN/INN) |
D10893 |
CYP3A |
|
|
| Acalabrutinib maleate (USAN) |
D11720 |
CYP3A |
|
|
| Acalabrutinib maleate hydrate (JAN) |
D12704 |
CYP3A |
|
|
| Aceneuramic acid (JAN/USAN) |
D11016 |
NPL |
|
|
| Acetone (NF) |
D02311 |
CYP2E1 |
|
|
| Acetylcholine chloride (JP18/USP/INN) |
D00999 |
ACHE |
|
|
| Acetylsalicylic acid and lansoprazole |
D10527 |
CYP2C19, CYP3A4 |
|
|
| Aclidinium bromide (JAN/USAN/INN) |
D08837 |
BCHE |
CYP2D6, CYP3A4, CYP3A5 |
|
| Aclidinium bromide and formoterol fumarate |
D11857 |
UGT |
|
|
| Adagrasib (USAN/INN) |
D12301 |
CYP3A4 |
|
|
| Ajmaline (JP18) |
D00199 |
CYP2D6 |
|
|
| Albuterol and budesonide |
D12757 |
SULT1A3 |
|
|
| Alectinib (USAN/INN) |
D10542 |
CYP3A4 |
|
|
| Alectinib hydrochloride (JAN) |
D10450 |
CYP3A4 |
|
|
| Alfuzosin (INN) |
D07124 |
CYP3A4 |
|
|
| Alfuzosin hydrochloride (JAN/USAN) |
D01692 |
CYP3A4 |
|
|
| Aliskiren (USAN/INN) |
D03208 |
CYP3A4 |
|
|
| Aliskiren fumarate (JAN/USAN) |
D06412 |
CYP3A4 |
|
|
| Allopurinol (JP18/USP/INN) |
D00224 |
|
CYP1A2 |
|
| Allopurinol sodium |
D07564 |
|
CYP1A2 |
|
| Almotriptan (USAN) |
D02824 |
MAOA, CYP3A4, CYP2D6; FMO3 |
|
|
| Almotriptan malate (USP) |
D02825 |
MAOA, CYP3A4, CYP2D6; FMO3 |
|
|
| Alosetron (INN) |
D07129 |
CYP1A2; CYP3A4, CYP2C9 |
|
|
| Alosetron hydrochloride (USAN) |
D02829 |
CYP1A2; CYP3A4, CYP2C9 |
|
|
| Alprazolam (JP18/USP/INN) |
D00225 |
CYP3A |
|
|
| Alprenolol (INN) |
D07156 |
CYP2D6 |
|
|
| Alprenolol hydrochloride (JP18/USAN) |
D01182 |
CYP2D6 |
|
|
| Amenamevir (JAN/INN) |
D10564 |
CYP3A |
|
CYP3A, CYP2B6 |
| Amfetamine (INN) |
D07445 |
CYP2D6 |
|
|
| Amifampridine (USAN/INN) |
D10228 |
NAT |
|
|
| Amifampridine phosphate (JAN/USAN) |
D10689 |
NAT |
|
|
| Aminophylline (USP/INN) |
D00227 |
CYP1A2 |
|
|
| Aminophylline dihydrate |
D11630 |
CYP1A2 |
|
|
| Aminophylline hydrate (JP18) |
D05429 |
CYP1A2 |
|
|
| Amiodarone (USAN/INN) |
D02910 |
CYP3A4 |
|
|
| Amiodarone hydrochloride (JP18/USP) |
D00636 |
CYP3A4 |
|
|
| Amitriptyline (INN) |
D07448 |
CYP2D6; CYP1A2, CYP3A4, CYP2C19 |
|
|
| Amitriptyline hydrochloride (JP18/USP) |
D00809 |
CYP2D6; CYP1A2, CYP3A4, CYP2C19 |
|
|
| Amlodipine (USP/INN) |
D07450 |
CYP3A4 |
|
|
| Amlodipine benzoate |
D11881 |
CYP3A4 |
|
|
| Amlodipine besilate and atorvastatin calcium |
D08488 |
CYP3A4 |
|
|
| Amlodipine besylate (USP) |
D00615 |
CYP3A4 |
|
|
| Amlodipine maleate (USAN) |
D02914 |
CYP3A4 |
|
|
| Amobarbital (JP18/INN) |
D00555 |
|
|
CYP3A |
| Amobarbital sodium (JAN/USP) |
D02252 |
|
|
CYP3A |
| Amodiaquine (USP/INN) |
D02922 |
CYP2C8 |
|
|
| Amodiaquine hydrochloride (USP) |
D02466 |
CYP2C8 |
|
|
| Amoxapine (JP18/USP/INN) |
D00228 |
CYP2D6 |
|
|
| Amoxicillin hydrate, clarithromycin and lansoprazole |
D08774 |
CYP2C19, CYP3A4 |
CYP3A4 |
|
| Amphetamine sulfate (USP) |
D02074 |
CYP2D6 |
|
|
| Ampiroxicam (JP18/INN) |
D01397 |
CYP2C9 |
|
|
| Amprenavir (JAN/USAN/INN) |
D00894 |
CYP3A4 |
CYP3A |
CYP3A |
| Anagrelide (INN/BAN) |
D07455 |
CYP1A1, CYP1A2 |
|
|
| Anagrelide hydrochloride (USP) |
D02933 |
CYP1A1, CYP1A2 |
|
|
| Anagrelide hydrochloride hydrate (JAN) |
D10255 |
CYP1A1, CYP1A2 |
|
|
| Anamorelin hydrochloride (JAN/USAN) |
D08856 |
CYP3A4 |
|
|
| Anastrozole (JP18/USP/INN) |
D00960 |
|
CYP1A2, CYP2C9, CYP3A4 |
|
| Apalutamide (JAN/INN) |
D11040 |
CYP2C8, CYP3A4 |
|
CYP3A4, CYP2C19; CYP2C9 |
| Apixaban (JAN/USAN/INN) |
D03213 |
CYP3A4, CYP3A5 |
|
|
| Aprepitant (JAN/USP/INN) |
D02968 |
CYP3A4 |
CYP3A4 |
CYP3A4, CYP2C9 |
| Aprindine (USAN/INN) |
D02969 |
CYP2D6 |
|
|
| Aprindine hydrochloride (JP18/USAN) |
D01326 |
CYP2D6 |
|
|
| Aprocitentan (USAN/INN) |
D11441 |
UGT1A1, UGT2B7 |
|
|
| Aranidipine (JAN/INN) |
D01562 |
CYP3A4 |
|
|
| Argatroban (USP) |
D00181 |
CYP3A4 |
|
|
| Aripiprazole (JAN/USP/INN) |
D01164 |
CYP3A4, CYP2D6 |
|
|
| Aripiprazole cavoxil (USAN) |
D10355 |
CYP3A4, CYP2D6 |
|
|
| Aripiprazole hydrate (JAN) |
D10516 |
CYP3A4, CYP2D6 |
|
|
| Aripiprazole lauroxil (USAN) |
D10364 |
CYP3A4, CYP2D6 |
|
|
| Armodafinil (USAN/INN) |
D03215 |
CYP3A4, CYP3A5 |
|
|
| Artemether and lumefantrine |
D02484 |
CYP3A |
|
|
| Asciminib (USAN/INN) |
D11403 |
CYP3A4, UGT2B7, UGT2B17 |
|
|
| Asciminib hydrochloride (JAN/USAN) |
D11404 |
CYP3A4, UGT2B7, UGT2B17 |
|
|
| Asenapine (INN) |
D11769 |
CYP1A2 |
CYP2D6 |
|
| Asenapine maleate (JAN/USAN) |
D02995 |
CYP1A2 |
CYP2D6 |
|
| Aspirin and omeprazole |
D11616 |
CYP2C19; CYP3A4 |
|
|
| Astemizole (JAN/USP/INN) |
D00234 |
CYP3A |
|
|
| Asunaprevir (JAN/USAN) |
D10093 |
CYP3A |
CYP2D6 |
CYP3A4 |
| Atazanavir (INN) |
D07471 |
|
CYP3A4, UGT1A1 |
|
| Atazanavir and cobicistat |
D10753 |
CYP3A4 |
CYP3A, CYP2D6; CYP2C8, UGT1A1 |
|
| Atazanavir sulfate (JAN/USAN) |
D01276 |
|
CYP3A4, UGT1A1 |
|
| Atenolol (JP18/USP/INN) |
D00235 |
CYP2D6 |
|
|
| Atogepant (USAN) |
D11313 |
CYP3A4 |
|
|
| Atomoxetine (USP/INN) |
D07473 |
CYP2D6 |
|
|
| Atomoxetine hydrochloride (JAN/USP) |
D02574 |
CYP2D6 |
|
|
| Atorvastatin (INN) |
D07474 |
CYP3A4 |
|
|
| Atorvastatin calcium (USP) |
D02258 |
CYP3A4 |
|
|
| Atorvastatin calcium anhydorous |
D00887 |
CYP3A4 |
|
|
| Atorvastatin calcium propylene glycol solvate |
D11095 |
CYP3A4 |
|
|
| Atovaquone and proguanil hydrochloride |
D02472 |
CYP2C19 |
|
|
| Avacopan (JAN/USAN/INN) |
D11093 |
CYP3A4 |
|
|
| Avanafil (USAN/INN) |
D03217 |
CYP3A4 |
|
|
| Avatrombopag (USAN/INN) |
D10306 |
CYP3A4, CYP2C9 |
|
|
| Avatrombopag maleate (JAN/USAN) |
D10307 |
CYP3A4, CYP2C9 |
|
|
| Axitinib (JAN/USAN) |
D03218 |
CYP3A4, CYP3A5 |
|
|
| Azelastine hydrochloride and fluticasone propionate |
D11656 |
CYP3A4 |
|
|
| Azelnidipine (JP18/INN) |
D01145 |
CYP3A4 |
|
|
| Azilsartan (JAN/USAN/INN) |
D08864 |
CYP2C9 |
|
|
| Azilsartan and amlodipine besilate |
D10524 |
CYP3A4 |
|
|
| Barnidipine (INN) |
D07494 |
CYP3A4 |
|
|
| Barnidipine hydrochloride (JAN) |
D01104 |
CYP3A4 |
|
|
| Beclomethasone dipropionate (USP) |
D00689 |
CYP3A4 |
|
|
| Beclomethasone dipropionate monohydrate |
D11572 |
CYP3A4 |
|
|
| Bedaquiline (USAN/INN) |
D09872 |
CYP3A4 |
|
|
| Bedaquiline fumarate (JAN/USAN) |
D09873 |
CYP3A4 |
|
|
| Belinostat (USAN/INN) |
D08870 |
UGT1A1; CYP2A6, CYP2C9, CYP3A4 |
|
|
| Belzutifan (JAN/USAN/INN) |
D11954 |
UGT2B17, CYP2C19; CYP3A4 |
|
|
| Benazepril (INN) |
D07499 |
UGT |
|
|
| Benazepril hydrochloride (JAN/USP) |
D00620 |
UGT |
|
|
| Benidipine (INN) |
D07509 |
CYP3A4 |
|
|
| Benidipine hydrochloride (JP18) |
D02045 |
CYP3A4 |
|
|
| Benzbromarone (JP18/USAN/INN) |
D01056 |
CYP2C9 |
CYP2C9 |
|
| Benzhydrocodone (USAN/INN) |
D10612 |
CYP2D6, CYP3A4 |
|
|
| Benzhydrocodone and acetaminophen |
D11628 |
CYP2D6, CYP3A4 |
|
|
| Benzhydrocodone hydrochloride (USAN) |
D10692 |
CYP2D6, CYP3A4 |
|
|
| Bepridil (INN) |
D07520 |
CYP2D6, CYP2C9, CYP3A4 |
CYP2D6 |
|
| Bepridil hydrochloride (USAN) |
D00631 |
CYP2D6, CYP2C9, CYP3A4 |
CYP2D6 |
|
| Berotralstat (USAN/INN) |
D11673 |
|
CYP2D6, CYP3A4 |
|
| Berotralstat hydrochloride (JAN/USAN) |
D11674 |
|
CYP2D6, CYP3A4 |
|
| Berythromycin (USAN/INN) |
D03098 |
CYP3A |
CYP3A |
|
| Betamethasone acetate and betamethasone sodium phosphate |
D04446 |
CYP3A4 |
|
|
| Betamethasone and d-chlorpheniramine maleate |
D04447 |
CYP3A4 |
|
|
| Bexagliflozin (USAN) |
D10865 |
UGT1A9; CYP3A |
|
|
| Bexarotene (JAN/USAN/INN) |
D03106 |
|
|
CYP3A |
| Bicalutamide (JP18/USP/INN) |
D00961 |
|
CYP3A4 |
|
| Blonanserin (JAN/INN) |
D01176 |
CYP3A4 |
|
|
| Boceprevir (INN/USAN) |
D08876 |
|
CYP3A |
|
| Bopindolol (INN) |
D07537 |
CYP2D6 |
|
|
| Bopindolol malonate (JAN) |
D01794 |
CYP2D6 |
|
|
| Bosentan (INN) |
D07538 |
CYP2C9, CYP3A4 |
|
CYP2C9, CYP3A4 |
| Bosentan (USAN) |
D01227 |
CYP2C9, CYP3A4 |
|
CYP2C9, CYP3A4 |
| Bosutinib (USAN) |
D03252 |
CYP3A4 |
|
|
| Bosutinib hydrate (JAN) |
D09728 |
CYP3A4 |
|
|
| Brexpiprazole (JAN/USAN/INN) |
D10309 |
CYP3A4, CYP2D6 |
|
|
| Brigatinib (JAN/USAN) |
D10866 |
CYP3A4 |
|
|
| Brincidofovir (USAN) |
D10547 |
CYP4F2 |
|
|
| Brinzolamide and timolol maleate |
D10512 |
CYP3A4, CYP2D6; CYP2A6, CYP2B6, CYP2C8, CYP2C9 |
|
|
| Brivaracetam (JAN/USAN/INN) |
D08879 |
CYP2C19 |
|
|
| Bromocriptine (USAN/INN) |
D03165 |
CYP3A4 |
CYP3A4 |
|
| Bromocriptine mesylate (USP) |
D00780 |
CYP3A4 |
CYP3A4 |
|
| Bromperidol (JAN/USAN/INN) |
D01101 |
CYP3A4 |
|
|
| Bromperidol decanoate (USAN) |
D02626 |
CYP3A4 |
|
|
| Brotizolam (JP18/USAN/INN) |
D01744 |
CYP3A4 |
|
|
| Budesonide (JP18/USP/INN) |
D00246 |
CYP3A4 |
|
|
| Budesonide and formoterol fumarate dihydrate |
D09595 |
CYP3A4, UGT |
|
|
| Bunitrolol hydrochloride (JAN) |
D01444 |
CYP2D6 |
|
|
| Bupivacaine (USAN/INN) |
D07552 |
CYP3A4 |
|
|
| Bupivacaine hydrochloride (USP) |
D01450 |
CYP3A4 |
|
|
| Buprenorphine (JAN/INN) |
D07132 |
CYP3A4 |
|
|
| Buprenorphine hydrochloride (JP18/USP) |
D00836 |
CYP3A4 |
|
|
| Butalbital, acetaminophen, caffeine and codeine phosphate |
D11851 |
CYP1A2, UGT2B7, UGT2B4; CYP3A4, CYP2D6 |
|
|
| Butalbital, aspirin, caffeine and codeine |
D11860 |
UGT2B7, UGT2B4, CYP3A4, CYP2D6 |
|
|
| Cabazitaxel (USAN/INN) |
D09755 |
CYP3A |
|
|
| Cabazitaxel acetonate (JAN) |
D10452 |
CYP3A |
|
|
| Cabergoline (JP18/USP/INN) |
D00987 |
CYP3A4 |
|
|
| Cabotegravir (JAN/USAN/INN) |
D10548 |
UGT1A1; UGT1A9 |
|
|
| Cabotegravir and rilpivirine |
D11966 |
UGT1A1, CYP3A; UGT1A9 |
|
|
| Cabotegravir sodium (JAN/USAN) |
D10549 |
UGT1A1; UGT1A9 |
|
|
| Caffeine (USP) |
D00528 |
CYP1A2; CYP3A4, CYP2E1 |
|
|
| Caffeine citrate (USP) |
D07603 |
CYP1A2; CYP3A4, CYP2E1 |
|
|
| Caffeine hydrate (JP18) |
D01453 |
CYP1A2; CYP3A4, CYP2E1 |
|
|
| Calcifediol (USP/INN) |
D00122 |
CYP27B1, CYP24A1 |
|
|
| Canagliflozin (USAN/INN) |
D09592 |
UGT1A9, UGT2B4 |
|
|
| Candesartan (USAN/INN) |
D00522 |
CYP2C9 |
|
|
| Candesartan cilexetil (JP18/USP) |
D00626 |
CES, CYP2C9 |
|
|
| Candesartan cilexetil and anmlodipine besylate (JP18) |
D07569 |
CYP3A4 |
|
|
| Cannabidiol (JAN/USAN/INN) |
D10915 |
CYP3A4, CYP2C19, UGT1A7, UGT1A9, UGT2B7 |
|
|
| Capecitabine (JAN/USP/INN) |
D01223 |
CYP2C9 |
|
|
| Capivasertib (JAN/USAN) |
D11371 |
CYP3A4, UGT2B7 |
|
|
| Capmatinib (USAN/INN) |
D10696 |
CYP3A4, AOX1 |
|
|
| Capmatinib hydrochloride (USAN) |
D10891 |
CYP3A4, AOX1 |
|
|
| Carbamazepine (JP18/USP/INN) |
D00252 |
CYP3A4 |
|
CYP3A4 |
| Carbidopa, levodopa and entacapone |
D10293 |
|
CYP2C9, COMT |
|
| Cariprazine (USAN/INN) |
D09997 |
CYP3A4; CYP2D6 |
|
|
| Cariprazine hydrochloride (JAN/USAN) |
D09876 |
CYP3A4; CYP2D6 |
|
|
| Carisoprodol (JAN/USP/INN) |
D00768 |
CYP2C19 |
|
|
| Carisoprodol and aspirin |
D11586 |
CYP2C19 |
|
|
| Carisoprodol, aspirin and codeine phosphate |
D11587 |
CYP2C19 |
|
|
| Carotegrast methyl (JAN) |
D09799 |
|
CYP3A4 |
|
| Carteolol (INN) |
D07624 |
CYP2D6 |
|
|
| Carteolol hydrochloride (JP18/USP) |
D00599 |
CYP2D6 |
|
|
| Carvedilol (JP18/USP/INN) |
D00255 |
CYP2D6, CYP2C9, CYP3A4, CYP1A2, CYP2E1 |
|
|
| Carvedilol phosphate (USAN) |
D03415 |
CYP2D6, CYP2C9, CYP3A4, CYP1A2, CYP2E1 |
|
|
| Celecoxib (JP18/USP/INN) |
D00567 |
CYP2C9 |
CYP2D6 |
|
| Cenobamate (USAN/INN) |
D11150 |
UGT2B7, CYP2E1, CYP2A6, CYP2B6; UGT2B4, CYP2C19, CYP3A4, CYP3A5 |
|
|
| Ceritinib (JAN/USAN/INN) |
D10551 |
CYP3A |
CYP2C9 |
|
| Cerivastatin (INN) |
D07661 |
CYP2C8, CYP3A4 |
|
|
| Cerivastatin sodium (JAN/USAN) |
D00889 |
CYP2C8, CYP3A4 |
|
|
| Cevimeline (INN) |
D07667 |
CYP2D6, CYP3A4 |
|
|
| Cevimeline hydrochloride (USAN) |
D00661 |
CYP2D6, CYP3A4 |
|
|
| Chloramphenicol (JP18/USP/INN) |
D00104 |
|
CYP2C19 |
|
| Chlorpheniramine polistirex and codeine polistirex |
D12313 |
UGT2B7, UGT2B4, CYP3A4, CYP2D6 |
|
|
| Chlorpromazine (USP/INN) |
D00270 |
CYP2D6 |
CYP2D6 |
|
| Chlorpromazine hibenzate (JAN) |
D03274 |
CYP2D6 |
CYP2D6 |
|
| Chlorpromazine hydrochloride (JP18/USP) |
D00789 |
CYP2D6 |
CYP2D6 |
|
| Chlorpromazine hydrochloride, promethazine hydrochloride and phenobarbital |
D02615 |
CYP3A, CYP2D6 |
|
|
| Chlorpromazine phenolphthalinate (JAN) |
D04034 |
CYP2D6 |
CYP2D6 |
|
| Chlorpromazine tannate (JAN) |
D09819 |
CYP2D6 |
CYP2D6 |
|
| Choline fenofibrate (USAN/INN) |
D08890 |
UGT |
|
|
| Ciclesonide (JAN/USAN/INN) |
D01703 |
CYP3A4 |
|
|
| Cifenline (USAN) |
D03492 |
CYP2D6, CYP3A4 |
|
|
| Cifenline succinate (USAN) |
D01455 |
CYP2D6, CYP3A4 |
|
|
| Cilnidipine (JP18/INN) |
D01173 |
CYP3A4; CYP2C19 |
|
|
| Cilostazol (JP18/USP/INN) |
D01896 |
CYP3A4; CYP2D6, CYP2C19 |
|
|
| Cimetidine (JP18/USP/INN) |
D00295 |
|
CYP2D6, CYP3A4 |
|
| Cimetidine hydrochloride (USP) |
D03503 |
|
CYP2D6, CYP3A4 |
|
| Cinacalcet (USAN) |
D03504 |
CYP3A4 |
CYP2D6 |
|
| Cinacalcet hydrochloride (JAN/USAN) |
D03505 |
CYP3A4 |
CYP2D6 |
|
| Cinnarizine (JAN/USAN/INN) |
D01295 |
CYP2D6 |
|
|
| Cinnarizine dihydrochloride |
D07734 |
CYP2D6 |
|
|
| Ciprofloxacin (JP18/USP/INN) |
D00186 |
|
CYP1A2 |
|
| Ciprofloxacin hydrate (JAN) |
D10822 |
|
CYP1A2 |
|
| Ciprofloxacin hydrochloride (USP) |
D02216 |
|
CYP1A2 |
|
| Ciprofloxacin lactate |
D07702 |
|
CYP1A2 |
|
| Cisapride (JAN) |
D02092 |
CYP3A |
|
|
| Cisapride (USP/INN) |
D00274 |
CYP3A |
|
|
| Citalopram (USP/INN) |
D07704 |
CYP3A4, CYP2D6 |
CYP2C19 |
|
| Citalopram hydrobromide (USP) |
D00822 |
CYP3A4, CYP2D6 |
CYP2C19 |
|
| Citalopram hydrochloride |
D07705 |
CYP3A4, CYP2D6 |
CYP2C19 |
|
| Clarithromycin (JP18/USP/INN) |
D00276 |
CYP3A4 |
CYP3A4 |
|
| Clarithromycin lactobionate |
D07710 |
CYP3A4 |
CYP3A4 |
|
| Clemastine (USAN) |
D03535 |
|
CYP2D6 |
|
| Clemastine fumarate (JP18/USP) |
D00666 |
|
CYP2D6 |
|
| Clobazam (JAN/USAN/INN) |
D01253 |
CYP3A4, CYP2C19 |
|
|
| Clomipramine (INN) |
D07727 |
CYP2D6; CYP1A2, CYP3A4, CYP2C19 |
|
|
| Clomipramine hydrochloride (JP18/USP) |
D00811 |
CYP2D6; CYP1A2, CYP3A4, CYP2C19 |
|
|
| Clopidogrel (USP/INN) |
D07729 |
CYP2C19; CYP3A4, CYP1A2, CYP2B6 |
CYP2C8 |
|
| Clopidogrel besilate |
D10824 |
CYP2C19; CYP3A4, CYP1A2, CYP2B6 |
CYP2C8 |
|
| Clopidogrel bisulfate (USP) |
D00769 |
CYP2C19; CYP3A4, CYP1A2, CYP2B6 |
CYP2C8 |
|
| Clopidogrel hydrochloride |
D10823 |
CYP2C19; CYP3A4, CYP1A2, CYP2B6 |
CYP2C8 |
|
| Clopidogrel sulfate and aspirin |
D10513 |
CYP2C19; CYP1A2, CYP2B6, CYP3A4 |
CYP2C8 |
|
| Clotrimazole (JP18/USP/INN) |
D00282 |
|
CYP3A4 |
|
| Clozapine (JAN/USP/INN) |
D00283 |
CYP1A2, CYP3A4 |
|
|
| Co-Trimoxazole (BAN) |
D00285 |
|
CYP2C8, CYP2C9 |
|
| Cobicistat (JAN/USAN/INN) |
D09881 |
CYP3A; CYP2D6 |
CYP3A, CYP2D6 |
|
| Codeine (USP) |
D00195 |
UGT2B7, UGT2B4; CYP3A4, CYP2D6 |
|
|
| Codeine hydrochloride |
D07740 |
UGT2B7, UGT2B4; CYP3A4, CYP2D6 |
|
|
| Codeine phosphate (USP) |
D02101 |
UGT2B7, UGT2B4; CYP3A4, CYP2D6 |
|
|
| Codeine phosphate and chlorpheniramine maleate |
D12312 |
UGT2B7, UGT2B4; CYP3A4, CYP2D6 |
|
|
| Codeine polistirex (USAN) |
D03579 |
UGT2B7, UGT2B4; CYP3A4, CYP2D6 |
|
|
| Codeine sulfate (USP) |
D03580 |
UGT2B7, UGT2B4; CYP3A4, CYP2D6 |
|
|
| Colchicine (JP18/USP) |
D00570 |
CYP3A4 |
|
|
| Colforsin (USAN/INN) |
D03584 |
CYP3A |
|
|
| Colforsin daropate hydrochloride (JAN) |
D01697 |
CYP3A |
|
|
| Compound oxycodone (JP18) |
D02175 |
CYP3A4; CYP2D6 |
|
|
| Conivaptan (INN) |
D07748 |
CYP3A |
CYP3A |
|
| Conivaptan hydrochloride (JAN/USAN) |
D01236 |
CYP3A |
CYP3A |
|
| Copanlisib (USAN/INN) |
D10867 |
CYP3A; CYP1A1 |
|
|
| Copanlisib hydrochloride (USAN) |
D10797 |
CYP3A; CYP1A1 |
|
|
| Copanlisib hydrochloride hydrate (JAN) |
D10798 |
CYP3A; CYP1A1 |
|
|
| Crizotinib (JAN/USAN/INN) |
D09731 |
CYP3A4, CYP3A5 |
CYP2B6, CYP3A |
|
| Cyclophosphamide (INN) |
D07760 |
CYP2B6; CYP2A6, CYP2C8, CYP2C9, CYP3A4 |
|
|
| Cyclophosphamide (USP) |
D00287 |
CYP2B6; CYP2A6, CYP2C8, CYP2C9, CYP3A4 |
|
|
| Cyclosporine (USP) |
D00184 |
CYP3A4 |
CYP3A4 |
|
| Dabrafenib (USAN) |
D10064 |
CYP3A4, CYP2C8 |
|
CYP3A4, CYP2C9 |
| Dabrafenib mesylate (USAN) |
D10104 |
CYP3A4, CYP2C8 |
|
CYP3A4, CYP2C9 |
| Daclatasvir (USAN) |
D10065 |
CYP3A4 |
CYP3A, UGT1A1 |
|
| Daclatasvir dihydrochloride (USAN) |
D10105 |
CYP3A4 |
CYP3A, UGT1A1 |
|
| Daclatasvir, asunaprevir and beclabuvir |
D10882 |
CYP3A |
|
CYP3A4 |
| Dacomitinib (INN) |
D09883 |
|
CYP2D6 |
|
| Dacomitinib (USAN) |
D10514 |
|
CYP2D6 |
|
| Dantrolene (USAN/INN) |
D02347 |
CYP1A1, CYP1A2, CYP3A |
|
|
| Dantrolene sodium (USP) |
D02274 |
CYP1A1, CYP1A2, CYP3A |
|
|
| Dapagliflozin (JAN/USAN/INN) |
D08897 |
UGT1A9 |
|
|
| Dapagliflozin propanediol (USAN) |
D09763 |
UGT1A9 |
|
|
| Dapsone (USP) |
D00592 |
CYP2E1, CYP3A4 |
|
|
| Daridorexant (USAN/INN) |
D11886 |
CYP3A4 |
|
|
| Darifenacin (USAN/INN) |
D03654 |
CYP3A4, CYP2D6 |
|
|
| Darifenacin hydrobromide (JAN/USAN) |
D01699 |
CYP3A4, CYP2D6 |
|
|
| Darunavir (USAN/INN) |
D03656 |
CYP3A4 |
CYP3A4 |
|
| Darunavir ethanolate (JAN) |
D06478 |
CYP3A4 |
CYP3A4 |
|
| Darunavir hydrate |
D12637 |
CYP3A4 |
CYP3A4 |
|
| Darunavir propylene glycolate |
D12752 |
CYP3A4 |
CYP3A4 |
|
| Dasabuvir, ombitasvir, paritaprevir and ritonavir |
D10582 |
CYP3A, CYP2C8 |
CYP3A4, UGT1A1 |
|
| Dasatinib (JAN/INN) |
D03658 |
CYP3A4, FMO3, UGT |
|
|
| Dasatinib (USAN) |
D06414 |
CYP3A4, FMO3, UGT |
|
|
| Dasatinib laurylsulfate (USAN) |
D12609 |
CYP3A4, FMO3, UGT |
|
|
| Debrisoquin sulfate (USAN) |
D03664 |
CYP2D6 |
|
|
| Deferasirox (JAN/USAN/INN) |
D03669 |
UGT1A1, UGT1A3 |
CYP1A2, CYP2C8 |
CYP3A4 |
| Deflazacort (USAN/INN) |
D03671 |
CYP3A4 |
|
|
| Delamanid (JAN/USAN) |
D09785 |
CYP3A4, CYP1A1, CYP2D6, CYP2E1 |
|
|
| Delavirdine (INN) |
D07782 |
CYP3A |
CYP3A |
|
| Delavirdine mesylate (USAN) |
D00895 |
CYP3A |
CYP3A |
|
| Desvenlafaxine (INN) |
D07793 |
CYP3A4, UGT |
|
|
| Desvenlafaxine succinate (USAN) |
D02570 |
CYP3A4, UGT |
|
|
| Desvenlafaxine succinate anhydrous |
D11619 |
UGT; CYP3A4 |
|
|
| Deucravacitinib (JAN/USAN) |
D11817 |
CYP1A2; CYP2B6, CYP2D6, CES2, UGT1A9 |
|
|
| Dexamethasone (JP18/USP/INN) |
D00292 |
CYP3A4 |
|
CYP3A4 |
| Dexamethasone 21-acetate |
D07796 |
CYP3A4 |
|
CYP3A4 |
| Dexamethasone 21-tebutate |
D07799 |
CYP3A4 |
|
CYP3A4 |
| Dexamethasone 21-valerate |
D07800 |
CYP3A4 |
|
CYP3A4 |
| Dexamethasone acefurate (USAN/INN) |
D02591 |
CYP3A4 |
|
CYP3A4 |
| Dexamethasone acetate (JAN/USP) |
D02174 |
CYP3A4 |
|
CYP3A4 |
| Dexamethasone beloxil (USAN) |
D02592 |
CYP3A4 |
|
CYP3A4 |
| Dexamethasone cipecilate (JAN/INN) |
D07073 |
CYP3A4 |
|
CYP3A4 |
| Dexamethasone dipropionate (USAN) |
D01632 |
CYP3A4 |
|
CYP3A4 |
| Dexamethasone isonicotinate |
D07797 |
CYP3A4 |
|
CYP3A4 |
| Dexamethasone metasulfobenzoate sodium (JAN) |
D01510 |
CYP3A4 |
|
CYP3A4 |
| Dexamethasone palmitate (JAN) |
D01615 |
CYP3A4 |
|
CYP3A4 |
| Dexamethasone phenylpropionate |
D07801 |
CYP3A4 |
|
CYP3A4 |
| Dexamethasone phosphate |
D07802 |
CYP3A4 |
|
CYP3A4 |
| Dexamethasone sodium hemisulfate |
D07798 |
CYP3A4 |
|
CYP3A4 |
| Dexamethasone sodium phosphate (JAN/USP) |
D00975 |
CYP3A4 |
|
CYP3A4 |
| Dexamethasone valerate (JAN) |
D01948 |
CYP3A4 |
|
CYP3A4 |
| Dexchlorpheniramine (INN) |
D07803 |
CYP2D6, CYP3A |
CYP2D6 |
|
| Dexchlorpheniramine maleate (USP) |
D00668 |
CYP2D6, CYP3A |
CYP2D6 |
|
| Dexfenfluramine (INN) |
D07805 |
CYP2D6 |
|
|
| Dexfenfluramine hydrochloride (USAN) |
D03713 |
CYP2D6 |
|
|
| Dexlansoprazole (INN/USAN) |
D08903 |
CYP2C19, CYP3A4 |
CYP2C19 |
|
| Dexlansoprazole sesquihydrate |
D12816 |
CYP2C19, CYP3A4 |
CYP2C19 |
|
| Dexmedetomidine (USAN/INN) |
D00514 |
CYP2A6; CYP1A2, CYP2E1, CYP2D6, CYP2C19 |
|
|
| Dexmedetomidine hydrochloride (JAN/USP) |
D01205 |
CYP2A6; CYP1A2, CYP2E1, CYP2D6, CYP2C19 |
|
|
| Dextroamphetamine (USAN) |
D03740 |
CYP2D6 |
|
|
| Dextroamphetamine sulfate (USP) |
D02078 |
CYP2D6 |
|
|
| Dextromethorphan (USP) |
D03742 |
CYP2D6 |
|
|
| Dextromethorphan hydrobromide (USP) |
D00848 |
CYP2D6 |
|
|
| Dextromethorphan hydrobromide and bupropion hydrochloride |
D12493 |
CYP2D6 |
|
|
| Dextromethorphan hydrobromide and potassium cresolsulfonate |
D04340 |
CYP2D6, CYP3A4 |
|
|
| Dextromethorphan polistirex (USAN) |
D03744 |
CYP2D6 |
|
|
| Diazepam (JP18/USP/INN) |
D00293 |
CYP2C19, CYP3A4 |
|
|
| Diclofenac (USAN/INN) |
D07816 |
CYP2C9 |
|
|
| Diclofenac calcium |
D07819 |
CYP2C9 |
|
|
| Diclofenac diethylamine |
D07817 |
CYP2C9 |
|
|
| Diclofenac epolamine |
D07818 |
CYP2C9 |
|
|
| Diclofenac potassium (USP) |
D00903 |
CYP2C9 |
|
|
| Diclofenac sodium (JP18/USP) |
D00904 |
CYP2C9 |
|
|
| Dienogest (JAN/USAN/INN) |
D03799 |
CYP3A4 |
|
|
| Dienogest and estradiol valerate |
D10461 |
CYP3A |
|
|
| Digitoxin (JAN/USP/INN) |
D00297 |
CYP3A |
|
|
| Dihydrocodeine (INN) |
D07831 |
UGT2B7, UGT2B4; CYP3A4, CYP2D6 |
|
|
| Dihydrocodeine bitartrate (USP) |
D03825 |
UGT2B7, UGT2B4; CYP3A4, CYP2D6 |
|
|
| Dihydrocodeine phosphate (JP18) |
D01481 |
UGT2B7, UGT2B4; CYP3A4, CYP2D6 |
|
|
| Dihydrocodeine phosphate, dl-methylephedrine hydrochloride and Chlorpheniramine maleate |
D04313 |
UGT2B7, UGT2B4; CYP3A4, CYP2D6 |
|
|
| Dihydrocodeine phosphate, ephedrine hydrochloride and ammmonium chloride |
D04338 |
UGT2B7, UGT2B4; CYP3A4, CYP2D6 |
|
|
| Dihydrocodeine thiocyanate |
D07832 |
UGT2B7, UGT2B4; CYP3A4, CYP2D6 |
|
|
| Dihydroergotamine (INN) |
D07837 |
CYP3A4 |
|
|
| Dihydroergotamine mesylate (USP) |
D02211 |
CYP3A4 |
|
|
| Dihydroergotamine tartrate |
D07838 |
CYP3A4 |
|
|
| Dihydroergotoxine |
D07839 |
CYP3A4 |
|
|
| Diltiazem (INN) |
D07845 |
CYP3A4 |
|
|
| Diltiazem hydrochloride (JP18/USP) |
D00616 |
CYP3A4 |
|
|
| Diltiazem malate (USAN) |
D03830 |
CYP3A4 |
|
|
| Disopyramide (JP18/USAN/INN) |
D00303 |
CYP3A4 |
|
|
| Disopyramide phosphate (JAN/USP) |
D00637 |
CYP3A4 |
|
|
| Disulfiram (JP18/USP/INN) |
D00131 |
|
CYP2E1, CYP1A2 |
|
| Docetaxel (JAN/INN) |
D07866 |
CYP3A4 |
|
|
| Docetaxel (USP) |
D02165 |
CYP3A4 |
|
|
| Dolasetron (INN) |
D07867 |
CYP2D6, CYP3A |
|
|
| Dolasetron mesylate (USP) |
D00725 |
CYP2D6, CYP3A |
|
|
| Dolutegravir (USAN) |
D10066 |
UGT1A1; CYP3A4 |
|
|
| Dolutegravir sodium (JAN/USAN) |
D10113 |
UGT1A1; CYP3A4 |
|
|
| Dolutegravir sodium and rilpivirine hydrochloride |
D11282 |
CYP3A, UGT1A1 |
|
|
| Dolutegravir, abacavir and lamivudine |
D10600 |
UGT1A1; CYP3A4 |
|
|
| Domperidone (JP18/USAN/INN) |
D01745 |
CYP3A4 |
|
|
| Domperidone maleate |
D07868 |
CYP3A4 |
|
|
| Donepezil (JAN/INN) |
D07869 |
CYP3A4; CYP2D6 |
|
|
| Donepezil hydrochloride (JP18/USP) |
D00670 |
CYP3A4; CYP2D6 |
|
|
| Dopamine (INN) |
D07870 |
MAOB, COMT |
|
|
| Dopamine hydrochloride (JP18/USP) |
D00633 |
MAOB, COMT |
|
|
| Doravirine (JAN/USAN/INN) |
D10624 |
CYP3A |
|
|
| Doravirine, lamivudine and tenofovir disoproxil |
D11396 |
CYP3A |
|
|
| Dorzolamide (INN) |
D07871 |
CYP2C9, CYP2C19, CYP3A4 |
|
|
| Dorzolamide hydrochloride (JP18/USP) |
D00653 |
CYP2C9, CYP2C19, CYP3A4 |
|
|
| Dorzolamide hydrochloride and timolol maleate (JP18) |
D08493 |
CYP2C9, CYP2C19, CYP3A4, CYP2D6 |
|
|
| Dosulepin (INN) |
D07872 |
CYP2D6 |
|
|
| Dothiepin hydrochloride (USAN) |
D01546 |
CYP2D6 |
|
|
| Doxapram (INN) |
D07873 |
CYP3A4, CYP3A5 |
|
|
| Doxapram hydrochloride (USP) |
D01872 |
CYP3A4, CYP3A5 |
|
|
| Doxepin (INN) |
D07875 |
CYP2C19, CYP2D6; CYP1A2, CYP2C9 |
|
|
| Doxepin hydrochloride (USP) |
D00814 |
CYP2C19, CYP2D6; CYP1A2, CYP2C9 |
|
|
| Dronedarone (INN) |
D02537 |
CYP3A |
CYP3A, CYP2D6 |
|
| Dronedarone hydrochloride (USP) |
D03914 |
CYP3A |
CYP3A, CYP2D6 |
|
| Droperidol and fentanyl citrate |
D03852 |
CYP3A4 |
|
|
| Drospirenone (JAN/USP/INN) |
D03917 |
CYP3A4 |
|
|
| Drospirenone and estradiol |
D12497 |
CYP3A4 |
|
|
| Drospirenone and ethinylestradiol |
D09741 |
CYP3A4 |
|
|
| Drospirenone, ethinyl estradiol and levomefolate calcium |
D12130 |
CYP3A4 |
|
|
| Duloxetine (INN) |
D07880 |
CYP1A2; CYP2D6 |
CYP2D6 |
|
| Duloxetine hydrochloride (JAN/USP) |
D01179 |
CYP1A2; CYP2D6 |
CYP2D6 |
|
| Dutasteride (JAN/USP/INN) |
D03820 |
CYP3A4, CYP3A5 |
|
|
| Dutasteride and tamsulosin |
D11389 |
CYP3A4, CYP3A5, CYP2D6 |
|
|
| Dydrogesterone (JP18/USP/INN) |
D01217 |
CYP3A4 |
|
|
| Ebastine (JP18/USAN/INN) |
D01478 |
CYP2J2, CYP3A4 |
|
|
| Efavirenz (JAN/USP/INN) |
D00896 |
CYP3A4, CYP2B6 |
|
CYP2B6, CYP3A4 |
| Elacestrant (USAN/INN) |
D11671 |
CYP3A4; CYP2A6, CYP2C9 |
|
|
| Elacestrant hydrochloride (USAN) |
D11672 |
CYP3A4; CYP2A6, CYP2C9 |
|
|
| Elafibranor (USAN) |
D11208 |
|
|
CYP3A4 |
| Elagolix, estradiol and norethisterone |
D12137 |
CYP3A; CYP2D6, CYP2C8, UGT |
|
|
| Elbasvir (JAN/USAN/INN) |
D10625 |
CYP3A |
|
|
| Eletriptan (INN) |
D07887 |
CYP3A4 |
|
|
| Eletriptan hydrobromide (JAN/USAN) |
D01973 |
CYP3A4 |
|
|
| Eletriptan hydrobromide monohydrate |
D11617 |
CYP3A4 |
|
|
| Elexacaftor, ivacaftor and tezacaftor |
D11700 |
CYP3A |
|
|
| Eliglustat (USAN/INN) |
D09893 |
CYP2D6; CYP3A4 |
|
|
| Eliglustat tartrate (JAN/USAN) |
D09894 |
CYP2D6; CYP3A4 |
|
|
| Elvitegravir, cobicistat, emtricitabine and tenofovir disoproxil |
D10756 |
CYP3A; CYP2D6 |
CYP3A, CYP2D6 |
|
| Empagliflozin (JAN/USAN/INN) |
D10459 |
UGT2B7, UGT1A3, UGT1A8, UGT1A9 |
|
|
| Emtricitabine and tenofovir alafenamide |
D10835 |
CTSA, CYP3A |
|
|
| Emtricitabine, rilpivirine and tenofovir alafenamide |
D10836 |
CTSA, CYP3A |
|
|
| Encainide (INN) |
D07894 |
CYP2D6 |
|
|
| Encainide hydrochloride (USAN) |
D03991 |
CYP2D6 |
|
|
| Encorafenib (JAN/USAN/INN) |
D11053 |
CYP3A4 |
|
|
| Enflurane (JP18/USP/INN) |
D00543 |
CYP2E1 |
|
|
| Enoxacin (USAN/INN) |
D00310 |
|
CYP1A2 |
|
| Enoxacin hydrate (JP18) |
D05461 |
|
CYP1A2 |
|
| Ensitrelvir (USAN/INN) |
D12619 |
CYP3A |
CYP3A |
|
| Ensitrelvir fumarate (USAN) |
D12353 |
CYP3A |
CYP3A |
|
| Entacapone (JP18/USP/INN) |
D00781 |
|
CYP2C9, COMT |
|
| Entrectinib (JAN/USAN/INN) |
D10926 |
CYP3A4 |
CYP3A |
|
| Enzalutamide (JAN/USAN) |
D10218 |
CYP2C8; CYP3A4 |
|
|
| Epinephrine (USP/INN) |
D00095 |
COMT, MAO |
|
|
| Epinephrine and lidocaine hydrochloride |
D04052 |
CYP1A2, CYP3A4 |
|
|
| Epinephrine bitartrate (JAN/USP) |
D02149 |
COMT, MAO |
|
|
| Epinephrine hydrochloride (JAN) |
D00996 |
COMT, MAO |
|
|
| Eplerenone (JP18/USAN/INN) |
D01115 |
CYP3A4 |
|
|
| Erdafitinib (JAN/USAN/INN) |
D10927 |
CYP2C9, CYP3A4 |
|
|
| Ergoloid mesylates (USP) |
D02268 |
CYP3A4 |
|
|
| Ergometrine (INN) |
D07905 |
CYP3A4 |
|
|
| Ergonovine maleate (USP) |
D01163 |
CYP3A4 |
|
|
| Ergotamine (INN) |
D07906 |
CYP3A4 |
|
|
| Ergotamine tartrate (JP18/USP) |
D00679 |
CYP3A4 |
|
|
| Eribulin mesylate (USAN) |
D08914 |
CYP3A4 |
|
|
| Erlotinib (INN) |
D07907 |
CYP3A4, CYP1A2 |
|
|
| Erlotinib hydrochloride (JAN/USAN) |
D04023 |
CYP3A4, CYP1A2 |
|
|
| Ertugliflozin (USAN/INN) |
D10313 |
UGT1A9, UGT2B7 |
|
|
| Ertugliflozin and sitagliptin |
D11066 |
UGT1A9, UGT2B7 |
|
|
| Ertugliflozin pidolate |
D11043 |
UGT1A9, UGT2B7 |
|
|
| Erythromycin (JP18/USP/INN) |
D00140 |
CYP3A |
CYP3A |
|
| Erythromycin acistrate (USAN) |
D02523 |
CYP3A |
CYP3A |
|
| Erythromycin estolate (USP) |
D00851 |
CYP3A |
CYP3A |
|
| Erythromycin ethylsuccinate (JP18/USP) |
D01361 |
CYP3A |
CYP3A |
|
| Erythromycin gluceptate (USP) |
D02524 |
CYP3A |
CYP3A |
|
| Erythromycin lactobionate (JP18/USP) |
D02009 |
CYP3A |
CYP3A |
|
| Erythromycin propionate (USAN) |
D02525 |
CYP3A |
CYP3A |
|
| Erythromycin salnacedin (USAN) |
D04054 |
CYP3A |
CYP3A |
|
| Erythromycin stearate (JP18/USP) |
D02184 |
CYP3A |
CYP3A |
|
| Erythromycin stinoprate (INN) |
D07910 |
CYP3A |
CYP3A |
|
| Erythromycin thiocyanate |
D07909 |
CYP3A |
CYP3A |
|
| Esaxerenone (JAN/INN) |
D10892 |
CYP3A |
|
|
| Escitalopram (INN) |
D07913 |
CYP3A4, CYP2C19, CYP2D6; MAO, AOX1 |
CYP2D6 |
|
| Escitalopram oxalate (JAN/USP) |
D02567 |
CYP3A4, CYP2C19, CYP2D6; MAO, AOX1 |
CYP2D6 |
|
| Esflurbiprofen (JAN) |
D10254 |
CYP2C9 |
|
|
| Esflurbiprofen and mentha oil |
D10746 |
CYP2C9 |
|
|
| Esketamine (USAN/INN) |
D07283 |
CYP2B6, CYP3A4; CYP2C9, CYP2C19, UGT |
|
|
| Esketamine hydrochloride (JAN/USAN) |
D10627 |
CYP2B6, CYP3A4; CYP2C9, CYP2C19, UGT |
|
|
| Eslicarbazepine (USAN/INN) |
D09215 |
|
CYP2C19 |
CYP3A4 |
| Eslicarbazepine acetate (USAN) |
D09612 |
|
CYP2C19 |
CYP3A4 |
| Esomeprazole (INN) |
D07917 |
CYP2C19; CYP3A4 |
|
|
| Esomeprazole magnesium (USP) |
D01984 |
CYP2C19; CYP3A4 |
|
|
| Esomeprazole magnesium dihydrate |
D11114 |
CYP2C19; CYP3A4 |
|
|
| Esomeprazole potassium (USAN) |
D09339 |
CYP2C19; CYP3A4 |
|
|
| Esomeprazole sodium (USAN) |
D04056 |
CYP2C19; CYP3A4 |
|
|
| Esomeprazole strontium (USAN) |
D10120 |
CYP2C19; CYP3A4 |
|
|
| Estazolam (JP18/USP/INN) |
D00311 |
CYP3A |
|
|
| Estradiol (JAN/USP/INN) |
D00105 |
CYP3A4 |
|
|
| Estradiol 17 beta-hemisuccinate |
D07919 |
CYP3A4 |
|
|
| Estradiol acetate (USAN) |
D04061 |
CYP3A4 |
|
|
| Estradiol and levonorgestrel |
D09187 |
CYP3A4 |
|
|
| Estradiol and norethindrone |
D09188 |
CYP3A4 |
|
|
| Estradiol benzoate (JP18/USP) |
D01953 |
CYP3A4 |
|
|
| Estradiol cypionate (USP) |
D04063 |
CYP3A4 |
|
|
| Estradiol dipropionate (JAN) |
D01617 |
CYP3A4 |
|
|
| Estradiol enanthate (USAN) |
D04064 |
CYP3A4 |
|
|
| Estradiol hemihydrate |
D07918 |
CYP3A4 |
|
|
| Estradiol undecylate (USAN/INN) |
D04065 |
CYP3A4 |
|
|
| Estradiol valerate (JAN/USP/INN) |
D01413 |
CYP3A4 |
|
|
| Estrogens, conjugated (JAN/USP) |
D04070 |
CYP3A4 |
|
|
| Estrone (JAN/USP/INN) |
D00067 |
CYP3A4 |
|
|
| Estrone sodium sulfate |
D00312 |
CYP3A4 |
|
|
| Estropipate (USP) |
D00948 |
CYP3A4 |
|
|
| Eszopiclone (JAN/USP/INN) |
D02624 |
CYP3A4; CYP2E1 |
|
|
| Ethinyl estradiol (USP) |
D00554 |
CYP3A4 |
CYP3A4 |
|
| Ethinylestradiol propanesulfonate |
D07928 |
CYP3A4 |
CYP3A4 |
|
| Ethosuximide (JP18/USP/INN) |
D00539 |
CYP3A4 |
|
|
| Ethyl loflazepate (JP18/INN) |
D01293 |
CYP3A4 |
|
|
| Ethylmorphine (BAN) |
D07929 |
CYP3A4 |
|
|
| Ethylmorphine hydrochloride hydrate (JP18) |
D02205 |
CYP3A4 |
|
|
| Etizolam (JP18/INN) |
D01514 |
CYP2C9, CYP3A4 |
|
|
| Etrasimod (USAN) |
D10930 |
CYP2C8, CYP2C9, CYP3A4, UGT; CYP2C19, CYP2J2 |
|
|
| Etrasimod arginine (USAN) |
D10931 |
CYP2C8, CYP2C9, CYP3A4, UGT; CYP2C19, CYP2J2 |
|
|
| Etravirine (JAN/USAN/INN) |
D04112 |
CYP3A4, CYP2C9, CYP2C19 |
CYP2C9, CYP2C19 |
CYP3A4 |
| Everolimus (JAN/USAN/INN) |
D02714 |
CYP3A4 |
|
|
| Exemestane (JAN/USP/INN) |
D00963 |
CYP3A4 |
|
|
| Ezetimibe (JAN/USP/INN) |
D01966 |
UGT |
|
|
| Ezetimibe and atorvastatin |
D10385 |
CYP3A4 |
|
|
| Ezetimibe and rosuvastatin |
D11520 |
UGT |
|
|
| Famotidine (JP18/USP/INN) |
D00318 |
|
CYP1A2 |
|
| Favipiravir (JAN/USAN/INN) |
D09537 |
AOX1; XDH |
CYP2C8, AOX1 |
|
| Fedratinib (USAN/INN) |
D10630 |
CYP3A4, CYP2C19, FMO3 |
|
|
| Fedratinib hydrochloride (USAN) |
D11296 |
CYP3A4, CYP2C19, FMO3 |
|
|
| Felodipine (JP18/USP/INN) |
D00319 |
CYP3A4 |
|
|
| Fenfluramine (INN) |
D07945 |
CYP1A2, CYP2B6, CYP2D6; CYP2C9, CYP2C19, CYP3A4, CYP3A5 |
|
|
| Fenfluramine hydrochloride (JAN/USAN) |
D04148 |
CYP1A2, CYP2B6, CYP2D6; CYP2C9, CYP2C19, CYP3A4, CYP3A5 |
|
|
| Fenofibrate (JP18/USP/INN) |
D00565 |
UGT |
|
|
| Fentanyl (JAN/USP/INN) |
D00320 |
CYP3A4 |
|
|
| Fentanyl citrate (JP18/USP) |
D01399 |
CYP3A4 |
|
|
| Fentanyl hydrochloride (JAN) |
D10811 |
CYP3A4 |
|
|
| Fesoterodine (INN) |
D07226 |
CYP2D6, CYP3A4 |
|
|
| Fesoterodine fumarate (JAN/USAN) |
D08923 |
CYP2D6, CYP3A4 |
|
|
| Fexinidazole (USAN/INN) |
D11252 |
CYP3A4 |
|
|
| Fezolinetant (USAN) |
D11976 |
CYP1A2; CYP2C9, CYP2C19 |
|
|
| Fidaxomicin (JAN/USAN) |
D09394 |
|
CYP2C19, CYP2C9, CYP3A4 |
|
| Filgotinib (USAN/INN) |
D10871 |
CES1, CES2 |
|
|
| Filgotinib hydrochloride (USAN) |
D10872 |
CES1, CES2 |
|
|
| Filgotinib maleate (JAN/USAN) |
D11106 |
CES1, CES2 |
|
|
| Finasteride (JAN/USP/INN) |
D00321 |
CYP3A4 |
|
|
| Finasteride and tadalafil |
D12486 |
CYP3A4 |
|
|
| Finerenone (JAN/USAN/INN) |
D10633 |
CYP3A4; CYP2C8 |
|
|
| Fingolimod (INN) |
D10001 |
CYP4F2 |
|
|
| Fingolimod hydrochloride (JAN/USAN) |
D04187 |
CYP4F2 |
|
|
| Fingolimod lauryl sulfate |
D12549 |
CYP4F2 |
|
|
| Flecainide (INN) |
D07962 |
CYP2D6 |
|
|
| Flecainide acetate (JP18/USP) |
D00638 |
CYP2D6 |
|
|
| Flibanserin (USAN/INN) |
D02577 |
CYP3A4; CYP2C19 |
|
|
| Fluconazole (JP18/USP/INN) |
D00322 |
|
CYP2C19, CYP2C9, CYP3A4 |
|
| Flunarizine (INN) |
D07971 |
CYP2D6 |
|
|
| Flunarizine hydrochloride (JAN/USAN) |
D01303 |
CYP2D6 |
|
|
| Flunisolide (JAN/USP) |
D00324 |
CYP3A4 |
|
|
| Flunisolide acetate (USAN) |
D04214 |
CYP3A4 |
|
|
| Fluorouracil (JP18/USP/INN) |
D00584 |
DPYD |
|
|
| Fluorouracil sodium salt |
D07974 |
DPYD |
|
|
| Fluoxetine (USAN/INN) |
D00326 |
CYP2C9, CYP2D6 |
CYP2C19, CYP2D6, CYP3A |
|
| Fluoxetine hydrochloride (JAN/USP) |
D00823 |
CYP2C9, CYP2D6 |
CYP2C19, CYP2D6, CYP3A |
|
| Fluphenazine (INN) |
D07977 |
CYP2D6 |
|
|
| Fluphenazine decanoate (JAN/USP) |
D00793 |
CYP2D6 |
|
|
| Fluphenazine enanthate (JP18/USP) |
D00792 |
CYP2D6 |
|
|
| Fluphenazine hydrochloride (JAN/USP) |
D00791 |
CYP2D6 |
|
|
| Fluphenazine maleate (JAN) |
D02163 |
CYP2D6 |
|
|
| Flurbiprofen (JP18/USP/INN) |
D00330 |
CYP2C9 |
|
|
| Flurbiprofen axetil (JAN) |
D01475 |
CYP2C9 |
|
|
| Flurbiprofen sodium (USP) |
D02290 |
CYP2C9 |
|
|
| Fluticasone (INN) |
D07981 |
CYP3A4 |
|
|
| Fluticasone furoate (JAN/USAN/INN) |
D06315 |
CYP3A4 |
|
|
| Fluticasone furoate and vilanterol trifenatate |
D10501 |
CYP3A4 |
|
|
| Fluticasone propionate (JAN/USP) |
D01708 |
CYP3A4 |
|
|
| Fluticasone propionate and formoterol fumarate hydrate |
D10506 |
CYP3A4, UGT |
|
|
| Fluvastatin (INN) |
D07983 |
CYP2C9, CYP3A4 |
CYP2C9 |
|
| Fluvastatin sodium (JAN/USP) |
D00892 |
CYP2C9, CYP3A4 |
CYP2C9 |
|
| Fluvoxamine (INN) |
D07984 |
CYP2D6 |
CYP1A2, CYP2C19; CYP2C9, CYP2D6, CYP3A4 |
|
| Fluvoxamine maleate (JP18/USP) |
D00824 |
CYP2D6 |
CYP1A2, CYP2C19; CYP2C9, CYP2D6, CYP3A4 |
|
| Fomepizole (JAN/USAN/INN) |
D00707 |
|
CYP2D6, CYP2E1, CYP1A2, CYP2A6, CYP2C9, CYP3A4 |
|
| Formoterol (INN) |
D07990 |
UGT |
|
|
| Formoterol fumarate (USP) |
D01373 |
UGT |
|
|
| Formoterol fumarate hydrate (JP18) |
D05277 |
UGT |
|
|
| Fosamprenavir (INN) |
D02497 |
CYP3A4 |
CYP3A4 |
|
| Fosamprenavir calcium (USAN) |
D03835 |
CYP3A4 |
CYP3A4 |
|
| Fosamprenavir calcium hydrate (JAN) |
D02867 |
CYP3A4 |
CYP3A4 |
|
| Fosamprenavir sodium (USAN) |
D03837 |
CYP3A4 |
CYP3A4 |
|
| Fosaprepitant (INN) |
D10895 |
CYP3A4 |
CYP3A4 |
CYP3A4, CYP2C9 |
| Fosaprepitant dimeglumine (USAN) |
D06597 |
CYP3A4 |
CYP3A4 |
CYP3A4, CYP2C9 |
| Fosfluconazole (JAN/INN) |
D01429 |
|
CYP2C19, CYP2C9, CYP3A4 |
|
| Foslevodopa and foscarbidopa |
D12494 |
COMT, DDC |
|
|
| Fosnetupitant and palonosetron hydrochloride |
D10572 |
CYP3A4; CYP2C9, CYP2D6 |
|
|
| Fosphenytoin (INN) |
D07993 |
CYP2C9; CYP2C19 |
|
CYP3A4, CYP2B6 |
| Fosphenytoin sodium (USP) |
D02096 |
CYP2C9; CYP2C19 |
|
CYP3A4, CYP2B6 |
| Fosphenytoin sodium hydrate (JAN) |
D07595 |
CYP2C9; CYP2C19 |
|
CYP3A4, CYP2B6 |
| Fosravuconazole L-lysine ethanolate (JAN) |
D10762 |
|
CYP3A |
|
| Fostamatinib (USAN) |
D09347 |
CYP3A4 |
CYP3A |
|
| Fostamatinib disodium (USAN) |
D09348 |
CYP3A4 |
CYP3A |
|
| Fostemsavir (USAN) |
D10707 |
CYP3A |
|
|
| Fostemsavir tromethamine (USAN) |
D10708 |
CYP3A |
|
|
| Fruquintinib (JAN/USAN) |
D11977 |
CYP3A; CYP2C8, CYP2C9, CYP2C19 |
|
|
| Fulvestrant (JAN/USP/INN) |
D01161 |
CYP3A4 |
|
|
| Galantamine (USAN/INN) |
D04292 |
CYP2D6, CYP3A4 |
|
|
| Galantamine hydrobromide (JAN/USP) |
D02173 |
CYP2D6, CYP3A4 |
|
|
| Ganaxolone (USAN/INN) |
D04300 |
CYP3A4, CYP3A5, CYP2B6, CYP2C19, CYP2D6 |
|
|
| Gemfibrozil (JAN/USP/INN) |
D00334 |
|
CYP2C8 |
|
| Gemtuzumab ozogamicin (USAN) |
D03259 |
CYP3A4 |
|
|
| Gepirone hydrochloride (USAN) |
D04314 |
CYP3A4 |
|
|
| Gilteritinib (USAN/INN) |
D10709 |
CYP3A4 |
|
|
| Gilteritinib fumarate (JAN/USAN) |
D10800 |
CYP3A4 |
|
|
| Glimepiride (JP18/USP/INN) |
D00593 |
CYP2C9 |
|
|
| Glyburide (USP) |
D00336 |
CYP2C9, CYP3A4 |
|
|
| Glycopyrronium bromide and indacaterol maleate |
D10505 |
CYP3A4 |
|
|
| Granisetron (JAN/USAN/INN) |
D04370 |
CYP3A4, CYP1A1 |
|
|
| Granisetron hydrochloride (JAN/USP) |
D00677 |
CYP3A4, CYP1A1 |
|
|
| Grazoprevir (USAN) |
D10639 |
CYP3A |
CYP3A |
|
| Grazoprevir (USAN/INN) |
D11565 |
CYP3A |
CYP3A |
|
| Guanfacine (INN) |
D08031 |
CYP3A4, CYP3A5 |
|
|
| Guanfacine hydrochloride (JAN/USP) |
D00606 |
CYP3A4, CYP3A5 |
|
|
| Halofantrine (INN) |
D08033 |
|
CYP2D6 |
|
| Halofantrine hydrochloride (USAN) |
D02485 |
|
CYP2D6 |
|
| Haloperidol (JP18/USP/INN) |
D00136 |
CYP2D6, CYP3A4 |
|
|
| Haloperidol decanoate (JAN/USP) |
D01898 |
CYP2D6, CYP3A4 |
|
|
| Haloperidol lactate |
D08035 |
CYP2D6, CYP3A4 |
|
|
| Halothane (JP18/USP/INN) |
D00542 |
CYP2E1, CYP3A4 |
|
|
| Hemin (JAN) |
D10003 |
|
|
CYP3A4, CYP2D6 |
| Hydralazine (INN) |
D08044 |
NAT |
CYP2D6 |
|
| Hydralazine hydrochloride (JP18/USP) |
D01302 |
NAT |
CYP2D6 |
|
| Hydralazine polistirex (USAN) |
D04458 |
NAT |
CYP2D6 |
|
| Hydrocodone (INN) |
D08045 |
CYP3A4; CYP2D6, CYP2B6, CYP2C19 |
|
|
| Hydrocodone bitartrate (USP) |
D03725 |
CYP3A4; CYP2D6, CYP2B6, CYP2C19 |
|
|
| Hydrocodone hydrochloride |
D08046 |
CYP3A4; CYP2D6, CYP2B6, CYP2C19 |
|
|
| Hydrocodone polistirex (USAN) |
D04461 |
CYP3A4; CYP2D6, CYP2B6, CYP2C19 |
|
|
| Hydrocortisone (JP18/USP/INN) |
D00088 |
CYP3A |
|
|
| Hydrocortisone aceponate (INN) |
D06876 |
CYP3A |
|
|
| Hydrocortisone acetate (JP18/USP) |
D00165 |
CYP3A |
|
|
| Hydrocortisone butyrate (JP18/USP) |
D01619 |
CYP3A |
|
|
| Hydrocortisone caproate (JAN) |
D09796 |
CYP3A |
|
|
| Hydrocortisone cypionate |
D00976 |
CYP3A |
|
|
| Hydrocortisone hemisuccinate (USP) |
D04467 |
CYP3A |
|
|
| Hydrocortisone probutate (USAN) |
D01886 |
CYP3A |
|
|
| Hydrocortisone sodium phosphate (JP18/USP) |
D00977 |
CYP3A |
|
|
| Hydrocortisone sodium succinate (JP18/USP) |
D00978 |
CYP3A |
|
|
| Hydrocortisone succinate (JP18) |
D01442 |
CYP3A |
|
|
| Hydrocortisone valerate (USP) |
D02288 |
CYP3A |
|
|
| Hydromorphone (INN) |
D08047 |
UGT |
|
|
| Hydromorphone hydrochloride (JAN/USP) |
D00839 |
UGT |
|
|
| Hydroxychloroquine (INN) |
D08050 |
CYP2C8, CYP3A4 |
|
|
| Hydroxychloroquine sulfate (JAN/USP) |
D02114 |
CYP2C8, CYP3A4 |
|
|
| Ibrutinib (JAN/USAN) |
D10223 |
CYP3A |
|
|
| Ibuprofen (JP18/USP/INN) |
D00126 |
CYP2C9 |
|
|
| Ibuprofen aluminum (USAN) |
D04490 |
CYP2C9 |
|
|
| Ibuprofen arginine salt |
D08058 |
CYP2C9 |
|
|
| Ibuprofen lysine (USAN) |
D06606 |
CYP2C9 |
|
|
| Ibuprofen piconol (JP18/USAN) |
D01122 |
CYP2C9 |
|
|
| Ibuprofen sodium |
D08059 |
CYP2C9 |
|
|
| Ibuprofen sodium (USAN) |
D09760 |
CYP2C9 |
|
|
| Ibuprofen trelamine (USAN) |
D12597 |
CYP2C9 |
|
|
| Ibuprofen trelamine hydrochloride (USAN) |
D12598 |
CYP2C9 |
|
|
| Idelalisib (JAN/USAN/INN) |
D10560 |
CYP3A; UGT1A4 |
|
|
| Ifosfamide (JAN/USP/INN) |
D00343 |
CYP3A4 |
|
|
| Iguratimod (JAN/INN) |
D01146 |
NAT |
|
|
| Iloperidone (USAN/INN) |
D02666 |
CYP3A4, CYP2D6 |
|
|
| Imatinib (INN) |
D08066 |
CYP3A4 |
|
|
| Imatinib mesylate (USAN) |
D01441 |
CYP3A4 |
|
|
| Imidafenacin (JAN/INN) |
D06273 |
CYP3A4, UGT1A4 |
|
|
| Imipramine (INN) |
D08070 |
CYP2D6; CYP1A2, CYP3A4, CYP2C19 |
|
|
| Imipramine hydrochloride (JP18/USP) |
D00815 |
CYP2D6; CYP1A2, CYP3A4, CYP2C19 |
|
|
| Imipramine pamoate (USP) |
D08071 |
CYP2D6; CYP1A2, CYP3A4, CYP2C19 |
|
|
| Indacaterol (USAN/INN) |
D09318 |
CYP3A4 |
|
|
| Indacaterol acetate (JAN) |
D11009 |
CYP3A4 |
|
|
| Indacaterol maleate (JAN/USAN) |
D09319 |
CYP3A4 |
|
|
| Indinavir (USAN) |
D03833 |
CYP3A4 |
CYP3A4 |
|
| Indinavir sulfate (USP) |
D00897 |
CYP3A4 |
CYP3A4 |
|
| Indinavir sulfate ethanolate (JAN) |
D02861 |
CYP3A4 |
CYP3A4 |
|
| Insulin aspart (USP/INN) |
D04475 |
|
|
CYP1A2 |
| Insulin detemir (USAN/INN) |
D04539 |
|
|
CYP1A2 |
| Insulin glargine (USAN/INN) |
D03250 |
|
|
CYP1A2 |
| Insulin glulisine (USAN/INN) |
D04540 |
|
|
CYP1A2 |
| Insulin human (USP/INN) |
D03230 |
|
|
CYP1A2 |
| Insulin injection, biphasic isophane (BAN) |
D08080 |
|
|
CYP1A2 |
| Insulin lispro (USP/INN) |
D04477 |
|
|
CYP1A2 |
| Insulin zinc (USP) |
D04551 |
|
|
CYP1A2 |
| Insulin zinc, extended (USP) |
D04549 |
|
|
CYP1A2 |
| Insulin zinc, prompt (USP) |
D04550 |
|
|
CYP1A2 |
| Insulin, isophane (USP) |
D04547 |
|
|
CYP1A2 |
| Ipragliflozin (INN) |
D10196 |
UGT2B7 |
|
|
| Ipragliflozin L-proline (JAN) |
D10200 |
UGT2B7 |
|
|
| Iptacopan (USAN/INN) |
D12251 |
CYP2C8; CYP2D6, UGT1A1, UGT1A3, UGT1A8 |
|
|
| Iptacopan hydrochloride (USAN) |
D12252 |
CYP2C8; CYP2D6, UGT1A1, UGT1A3, UGT1A8 |
|
|
| Irbesartan (JP18/USP/INN) |
D00523 |
CYP2C9 |
|
|
| Irbesartan and amlodipine besilate (JP18) |
D10243 |
CYP3A4 |
|
|
| Irbesartan and trichlormethiazide |
D10480 |
CYP2C9, UGT |
|
|
| Irinotecan (INN) |
D08086 |
CES; CYP3A4, UGT1A1 |
|
|
| Irinotecan hydrochloride (USP) |
D01061 |
CES; CYP3A4, UGT1A1 |
|
|
| Irinotecan sucrosofate (USAN) |
D10642 |
CES; CYP3A4, UGT1A1 |
|
|
| Isavuconazonium (USAN) |
D10644 |
CYP3A |
CYP3A, UGT |
CYP2B6 |
| Isavuconazonium sulfate (JAN/USAN) |
D10643 |
CYP3A |
CYP3A, UGT |
CYP2B6 |
| Isoprenaline (INN) |
D08090 |
COMT |
|
|
| Isopropylantipyrine, ergotamine tartrate and anhydrous caffeine |
D07585 |
CYP3A4 |
|
|
| Isoproterenol hydrochloride (USP) |
D01390 |
COMT |
|
|
| Isoproterenol sulfate (USP) |
D02066 |
COMT |
|
|
| Istradefylline (JAN/USAN/INN) |
D04641 |
CYP1A1, CYP3A4, CYP3A5 |
CYP3A4, CYP3A5 |
|
| Itopride (INN) |
D08094 |
FMO1, FMO3 |
|
|
| Itopride hydrochloride (JAN) |
D02729 |
FMO1, FMO3 |
|
|
| Itraconazole (JP18/USP) |
D00350 |
CYP3A4 |
CYP3A4 |
|
| Ivabradine (USAN/INN) |
D07165 |
CYP3A4 |
|
|
| Ivabradine hydrochloride (JAN/USAN) |
D08095 |
CYP3A4 |
|
|
| Ivermectin (JAN/USP/INN) |
D00804 |
CYP3A4 |
|
|
| Ixabepilone (JAN/USAN/INN) |
D04645 |
CYP3A4 |
|
|
| Josamycin (JP18/USAN/INN) |
D01235 |
|
CYP3A4 |
|
| Josamycin propionate (JP18) |
D05351 |
|
CYP3A4 |
|
| Ketoconazole (JP18/USP) |
D00351 |
CYP3A4 |
CYP3A4 |
|
| Lacosamide (JAN/USAN/INN) |
D07299 |
CYP3A4, CYP2C9, CYP2C19 |
CYP2C19 |
|
| Lafutidine (JP18/INN) |
D01131 |
CYP3A4, CYP2D6 |
|
|
| Lamivudine, nevirapine and zidovudine |
D11521 |
CYP3A, CYP2B6, UGT |
|
CYP3A, CYP2B6 |
| Lamotrigine (JAN/USP/INN) |
D00354 |
UGT1A4 |
|
|
| Lanoconazole (JP18/INN) |
D01092 |
|
CYP2C9 |
|
| Lansoprazole (JP18/USP/INN) |
D00355 |
CYP2C19, CYP3A4 |
CYP2C19 |
|
| Lansoprazole, amoxicillin hydrate and metronidazole |
D09742 |
CYP2C19, CYP3A4 |
|
|
| Lapatinib (INN) |
D08108 |
CYP3A4, CYP3A5; CYP2C19, CYP2C8 |
|
|
| Lapatinib ditosylate (USAN) |
D04024 |
CYP3A4, CYP3A5; CYP2C19, CYP2C8 |
|
|
| Larotrectinib (USAN/INN) |
D11137 |
CYP3A |
|
|
| Larotrectinib sulfate (JAN/USAN) |
D11138 |
CYP3A |
|
|
| Lazertinib (USAN/INN) |
D11980 |
CYP3A4 |
|
|
| Lazertinib mesylate (USAN) |
D12245 |
CYP3A4 |
|
|
| Lefamulin (USAN/INN) |
D11631 |
CYP3A4 |
|
|
| Lefamulin acetate (USAN) |
D11632 |
CYP3A4 |
|
|
| Leflunomide (JAN/USP/INN) |
D00749 |
CYP3A4 |
CYP2C9 |
|
| Lemborexant (JAN/USAN/INN) |
D11022 |
CYP3A4; CYP3A5 |
|
|
| Lenacapavir (USAN/INN) |
D12161 |
UGT1A1, CYP3A |
|
|
| Lenacapavir sodium (JAN/USAN) |
D12162 |
UGT1A1, CYP3A |
|
|
| Leniolisib (USAN/INN) |
D11158 |
CYP3A4 |
|
|
| Leniolisib phosphate (JAN/USAN) |
D11159 |
CYP3A4 |
|
|
| Lenvatinib (USAN/INN) |
D09919 |
CYP3A |
|
|
| Lenvatinib mesylate (USAN) |
D09920 |
CYP3A |
|
|
| Lercanidipine (INN) |
D08111 |
CYP3A |
|
|
| Lercanidipine hydrochloride (JAN/USAN) |
D01849 |
CYP3A |
|
|
| Lesinurad (USAN/INN) |
D09921 |
CYP2C9 |
|
|
| Lesinurad sodium (USAN) |
D09922 |
CYP2C9 |
|
|
| Letermovir (JAN/USAN/INN) |
D10801 |
|
CYP3A |
CYP2C9, CYP2C19 |
| Letrozole (JAN/USP/INN) |
D00964 |
CYP3A4, CYP2A6 |
CYP2A6 |
|
| Levobupivacaine (INN) |
D08116 |
CYP3A4, CYP1A2 |
|
|
| Levobupivacaine hydrochloride (JAN/USAN) |
D01287 |
CYP3A4, CYP1A2 |
|
|
| Levocetirizine (USAN/INN) |
D07402 |
CYP3A4 |
|
|
| Levocetirizine dihydrochloride (USP) |
D08118 |
CYP3A4 |
|
|
| Levomethadyl acetate (USAN) |
D04716 |
CYP3A4 |
|
|
| Levomethadyl acetate hydrochloride (USAN) |
D00840 |
CYP3A4 |
|
|
| Lidocaine (JP18/USP/INN) |
D00358 |
CYP1A2, CYP3A4 |
|
|
| Lidocaine and prilocaine |
D02740 |
CYP1A2, CYP3A4 |
|
|
| Lidocaine and tetracaine |
D11553 |
CYP1A2; CYP3A4 |
|
|
| Lidocaine hydrochloride (JAN/USP) |
D02086 |
CYP1A2, CYP3A4 |
|
|
| Lidocaine hydrochloride and epinephrine bitartrate |
D04813 |
CYP1A2, CYP3A4 |
|
|
| Lidocaine hydrochloride monohydrate |
D08127 |
CYP1A2, CYP3A4 |
|
|
| Lomitapide (USAN/INN) |
D09637 |
CYP3A4 |
|
|
| Lomitapide mesylate (USAN) |
D09638 |
CYP3A4 |
|
|
| Loperamide (INN) |
D08144 |
CYP3A4, CYP2C8 |
|
|
| Loperamide hydrochloride (JAN/USP) |
D00729 |
CYP3A4, CYP2C8 |
|
|
| Loperamide oxide (INN) |
D07113 |
CYP3A4, CYP2C8 |
|
|
| Lopinavir (JAN/USP/INN) |
D01425 |
CYP3A |
CYP3A |
|
| Lopinavir and ritonavir |
D02498 |
CYP3A |
CYP3A |
|
| Loratadine (JAN/USP/INN) |
D00364 |
CYP2D6, CYP3A4 |
|
|
| Lorazepam (JP18/USP/INN) |
D00365 |
UGT2B7, UGT2B15 |
|
|
| Lorlatinib (JAN/USAN/INN) |
D11012 |
CYP3A |
|
CYP3A |
| Lornoxicam (JAN/USAN/INN) |
D01866 |
CYP2C9 |
|
|
| Losartan (INN) |
D08146 |
CYP2C9 |
|
|
| Losartan potassium (JP18/USP) |
D00357 |
CYP2C9 |
|
|
| Losartan potassium and hydrochlorothiazide (JP18) |
D07895 |
CYP2C9 |
|
|
| Lovastatin (USP/INN) |
D00359 |
CYP3A4 |
|
|
| Loxapine (USAN/INN) |
D02340 |
CYP1A2, CYP3A4, CYP2D6 |
|
|
| Loxapine hydrochloride |
D08148 |
CYP1A2, CYP3A4, CYP2D6 |
|
|
| Loxapine succinate (USP) |
D00794 |
CYP1A2, CYP3A4, CYP2D6 |
|
|
| Luliconazole (JAN/USAN/INN) |
D01980 |
|
CYP2B6, CYP2C8, CYP2C19, CYP3A4 |
|
| Lurasidone hydrochloride (JAN/USAN) |
D04820 |
CYP3A4 |
|
|
| Lusutrombopag (JAN/USAN/INN) |
D10476 |
CYP4A11 |
|
|
| Macitentan (JAN/USAN) |
D10135 |
CYP3A4 |
|
|
| Macitentan and tadalafil |
D12963 |
CYP3A; CYP2C8, CYP2C9, CYP2C19 |
|
|
| Manidipine (INN) |
D08155 |
CYP3A4 |
|
|
| Manidipine hydrochloride (JP18) |
D01553 |
CYP3A4 |
|
|
| Maprotiline (USAN) |
D02566 |
CYP2D6 |
|
|
| Maprotiline hydrochloride (JP18/USP) |
D00818 |
CYP2D6 |
|
|
| Maraviroc (JAN/INN) |
D06670 |
CYP3A4 |
|
|
| Maribavir (JAN/USAN/INN) |
D04859 |
CYP3A4; CYP1A2 |
|
|
| Mavacamten (JAN/USAN/INN) |
D12265 |
CYP2C19; CYP3A4, CYP2C9 |
|
|
| Mavorixafor (USAN) |
D11510 |
CYP3A4; CYP2D6 |
|
|
| Maxacalcitol (JAN/USAN/INN) |
D01098 |
CYP3A4 |
|
|
| Mefenamic acid (JP18/USP/INN) |
D00151 |
CYP2C9 |
|
|
| Mefloquine (USAN/INN) |
D04895 |
CYP3A |
|
|
| Mefloquine hydrochloride (JP18/USP) |
D00831 |
CYP3A |
|
|
| Melatonin (JAN) |
D08170 |
CYP1A2 |
|
|
| Meloxicam (JAN/USP/INN) |
D00969 |
CYP2C9; CYP3A4 |
|
|
| Mepenzolate bromide and phenobarbital |
D04059 |
|
|
CYP3A |
| Mephenytoin (USP/INN) |
D00375 |
CYP2C19 |
|
|
| Mephobarbital (JAN/USP) |
D00700 |
CYP2C19 |
|
|
| Mequitazine (JP18/INN) |
D01324 |
CYP2D6 |
|
|
| Metamfetamine (INN) |
D08187 |
CYP2D6 |
|
|
| Metformin hydrochloride and saxagliptin hydrochloride |
D10263 |
CYP3A4, CYP3A5 |
|
|
| Methadone (BAN) |
D08195 |
CYP3A4, CYP2B6; CYP2C8, CYP2C9, CYP2C19, CYP2D6 |
|
CYP3A4, CYP2B6 |
| Methadone hydrochloride (JAN/USP) |
D02102 |
CYP3A4, CYP2B6; CYP2C8, CYP2C9, CYP2C19, CYP2D6 |
|
CYP3A4, CYP2B6 |
| Methamphetamine hydrochloride (JP18/USP) |
D02242 |
CYP2D6 |
|
|
| Methoxsalen (JP18/USP) |
D00139 |
|
CYP2A6 |
|
| Methoxyflurane (USP/INN) |
D00544 |
CYP2E1, CYP3A4 |
|
|
| Methylene blue (USP) |
D02312 |
|
CYP1A2, CYP2B6, CYP2C9, CYP2C19 |
|
| Methylergometrine (INN) |
D08207 |
CYP3A4 |
|
|
| Methylergonovine maleate (USP) |
D00680 |
CYP3A4 |
|
|
| Methylprednisolone (JP18/USP/INN) |
D00407 |
CYP3A4 |
|
|
| Methylprednisolone aceponate (INN) |
D07203 |
CYP3A4 |
|
|
| Methylprednisolone acetate (JAN/USP) |
D00979 |
CYP3A4 |
|
|
| Methylprednisolone hemisuccinate (USP) |
D05000 |
CYP3A4 |
|
|
| Methylprednisolone sodium phosphate (USAN) |
D05001 |
CYP3A4 |
|
|
| Methylprednisolone sodium succinate (JAN/USP) |
D00751 |
CYP3A4 |
|
|
| Methylprednisolone suleptanate (USAN/INN) |
D05002 |
CYP3A4 |
|
|
| Methylthioninium chloride hydrate (JAN) |
D10537 |
|
CYP1A2, CYP2B6, CYP2C9, CYP2C19 |
|
| Metoclopramide (JP18/INN) |
D00726 |
CYP2D6 |
CYP2D6 |
|
| Metoclopramide hydrochloride (JAN) |
D02213 |
CYP2D6 |
CYP2D6 |
|
| Metoclopramide hydrochloride (USP) |
D05008 |
CYP2D6 |
CYP2D6 |
|
| Metoprolol (USAN/INN) |
D02358 |
CYP2D6 |
|
|
| Metoprolol and hydrochlorothiazide |
D10273 |
CYP2D6 |
|
|
| Metoprolol fumarate (USP) |
D05011 |
CYP2D6 |
|
|
| Metoprolol succinate (USP) |
D00635 |
CYP2D6 |
|
|
| Metoprolol tartrate (JP18/USP) |
D00601 |
CYP2D6 |
|
|
| Metronidazole (JP18/USP/INN) |
D00409 |
CYP2A6 |
CYP2C9 |
|
| Metronidazole benzoate (USP) |
D08214 |
CYP2A6 |
CYP2C9 |
|
| Metronidazole hydrochloride (USAN) |
D05016 |
CYP2A6 |
CYP2C9 |
|
| Metronidazole phosphate (USAN) |
D05017 |
CYP2A6 |
CYP2C9 |
|
| Mexazolam (JAN/INN) |
D01316 |
CYP3A4 |
|
|
| Mexiletine (INN) |
D08215 |
CYP1A2, CYP2D6 |
|
|
| Mexiletine hydrochloride (JP18/USP) |
D00639 |
CYP1A2, CYP2D6 |
|
|
| Mianserin (INN) |
D08216 |
CYP3A4, CYP1A2, CYP2D6 |
|
|
| Mianserin hydrochloride (JAN/USAN) |
D01358 |
CYP3A4, CYP1A2, CYP2D6 |
|
|
| Mibefradil (INN) |
D08217 |
|
CYP3A, CYP1A2, CYP2D6 |
|
| Mibefradil dihydrochloride (USAN) |
D05024 |
|
CYP3A, CYP1A2, CYP2D6 |
|
| Miconazole (JP18/USP/INN) |
D00416 |
|
CYP2C9, CYP3A |
|
| Miconazole nitrate (JP18/USP) |
D00882 |
|
CYP2C9, CYP3A |
|
| Midazolam (JAN/USP/INN) |
D00550 |
CYP3A4 |
|
|
| Midazolam hydrochloride (USAN) |
D00696 |
CYP3A4 |
|
|
| Midazolam maleate (USAN) |
D05028 |
CYP3A4 |
|
|
| Midecamycin (JP18/INN) |
D01339 |
|
CYP3A4 |
|
| Midecamycin acetate (JP18) |
D01636 |
|
CYP3A4 |
|
| Midodrine (INN) |
D08220 |
|
CYP2D6 |
|
| Midodrine hydrochloride (JAN/USP) |
D01307 |
|
CYP2D6 |
|
| Midostaurin (JAN/USAN/INN) |
D05029 |
CYP3A4 |
|
|
| Mifepristone (JAN/USAN/INN) |
D00585 |
CYP3A4 |
CYP3A |
|
| Mifepristone and misoprostol |
D12586 |
CYP3A |
CYP3A |
|
| Milrinone (JAN/USP/INN) |
D00417 |
UGT |
|
|
| Milrinone lactate |
D02085 |
UGT |
|
|
| Minaprine (USAN/INN) |
D05039 |
CYP2D6 |
|
|
| Minaprine hydrochloride (USAN) |
D05040 |
CYP2D6 |
|
|
| Mirabegron (JAN/USAN/INN) |
D09535 |
CYP3A4 |
CYP2D6 |
|
| Mirtazapine (JAN/USP/INN) |
D00563 |
CYP1A2, CYP2D6, CYP3A4 |
|
|
| Mirtazapine hydrate (JAN) |
D11056 |
CYP1A2, CYP2D6, CYP3A4 |
|
|
| Mirvetuximab soravtansine (USAN/INN) |
D10954 |
CYP3A4 |
|
|
| Mitiglinide calcium hydrate (JP18) |
D01854 |
UGT |
|
|
| Mobocertinib (USAN/INN) |
D12001 |
CYP3A |
|
|
| Mobocertinib succinate (JAN) |
D11969 |
CYP3A |
|
|
| Moclobemide (USAN/INN) |
D02561 |
CYP2C19 |
CYP2D6, CYP2C19 |
|
| Modafinil (JAN/USP/INN) |
D01832 |
CYP3A4 |
CYP2C9, CYP2C19 |
CYP1A2, CYP2B6, CYP3A4 |
| Mofezolac (JAN/INN) |
D01718 |
CYP2C9 |
|
|
| Momelotinib (USAN/INN) |
D10315 |
CYP3A4, CYP2C8, CYP2C9, CYP2C19, CYP1A2 |
|
|
| Momelotinib dihydrochloride (USAN) |
D10358 |
CYP3A4, CYP2C8, CYP2C9, CYP2C19, CYP1A2 |
|
|
| Momelotinib hydrochloride hydrate (JAN) |
D10889 |
CYP3A4, CYP2C8, CYP2C9, CYP2C19, CYP1A2 |
|
|
| Mometasone (INN) |
D08227 |
CYP3A4 |
|
|
| Mometasone furoate (JAN/USP) |
D00690 |
CYP3A4 |
|
|
| Mometasone furoate hydrate (JAN) |
D03325 |
CYP3A4 |
|
|
| Montelukast (INN) |
D08229 |
CYP2C8, CYP2C9, CYP3A4 |
|
|
| Montelukast sodium (JP18/USP) |
D00529 |
CYP2C8, CYP2C9, CYP3A4 |
|
|
| Moricizine (USAN) |
D05077 |
|
|
CYP1A2 |
| Moricizine hydrochloride (USP) |
D02087 |
|
|
CYP1A2 |
| Morphine (BAN) |
D08233 |
UGT |
|
|
| Morphine hydrochloride hydrate (JP18) |
D02271 |
UGT |
|
|
| Morphine sulfate (USP) |
D00842 |
UGT |
|
|
| Morphine tartrate |
D08234 |
UGT |
|
|
| Mosapride (INN) |
D08236 |
CYP3A4 |
|
|
| Mosapride citrate hydrate (JP18) |
D01994 |
CYP3A4 |
|
|
| Mozavaptane hydrochloride (JAN) |
D01855 |
CYP3A4, CYP2C8 |
|
|
| Naldemedine (USAN/INN) |
D10188 |
CYP3A4 |
|
|
| Naldemedine tosylate (JAN/USAN) |
D10478 |
CYP3A4 |
|
|
| Nalfurafine hydrochloride (JAN/USAN) |
D06405 |
CYP3A4 |
|
|
| Naloxegol (USAN/INN) |
D10479 |
CYP3A |
|
|
| Naloxegol oxalate (USAN) |
D10375 |
CYP3A |
|
|
| Naproxen and esomeprazole magnesium |
D11576 |
CYP2C9, CYP1A2, CYP2C19; CYP3A4 |
|
|
| Naratriptan (INN) |
D08255 |
CYP1A2, CYP2C9, CYP2D6, CYP2E1, CYP3A4, CYP3A5 |
|
|
| Naratriptan hydrochloride (JAN/USP) |
D00674 |
CYP1A2, CYP2C9, CYP2D6, CYP2E1, CYP3A4, CYP3A5 |
|
|
| Nateglinide (JP18/USP/INN) |
D01111 |
CYP2C9 |
|
|
| Nebivolol (USAN/INN) |
D05127 |
CYP2D6 |
|
|
| Nebivolol hydrochloride (USAN) |
D06622 |
CYP2D6 |
|
|
| Nelarabine (JAN/USAN/INN) |
D05134 |
ADA |
|
|
| Nelfinavir (INN) |
D08259 |
CYP3A4; CYP2C19 |
CYP3A4 |
|
| Nelfinavir mesylate (USAN/INN) |
D00899 |
CYP3A4; CYP2C19 |
CYP3A4 |
|
| Nemonapride (JAN/INN) |
D01468 |
CYP3A4 |
|
|
| Neratinib (USAN/INN) |
D08950 |
CYP3A4; FMO |
|
|
| Neratinib maleate |
D10898 |
CYP3A4; FMO |
|
|
| Netupitant (USAN/INN) |
D05152 |
CYP3A |
CYP3A |
|
| Nevirapine (JAN/USP/INN) |
D00435 |
CYP3A4, CYP2B6, CYP2D6 |
|
|
| Nicardipine (INN) |
D08270 |
CYP3A4 |
|
|
| Nicardipine hydrochloride (JP18/USAN) |
D00617 |
CYP3A4 |
|
|
| Nicotine (USP) |
D03365 |
CYP2A6 |
|
CYP1A2 |
| Nicotine bitartrate (USAN) |
D05156 |
CYP2A6 |
|
CYP1A2 |
| Nicotine polacrilex (USP) |
D05157 |
CYP2A6 |
|
CYP1A2 |
| Nifedipine (JP18/USP/INN) |
D00437 |
CYP3A4 |
|
|
| Nilotinib (USAN/INN) |
D08953 |
CYP3A4; CYP2C8 |
|
|
| Nilotinib hydrochloride dihydrate (JAN) |
D12444 |
CYP3A4; CYP2C8 |
|
|
| Nilotinib hydrochloride hydrate (JAN) |
D06413 |
CYP3A4; CYP2C8 |
|
|
| Nilotinib laurylsulfate (USAN) |
D12854 |
CYP3A4; CYP2C8 |
|
|
| Nilvadipine (JP18/USAN/INN) |
D01908 |
CYP3A4 |
|
|
| Nimodipine (USP/INN) |
D00438 |
CYP3A4 |
|
|
| Nintedanib (USAN/INN) |
D10481 |
UGT |
|
|
| Nintedanib esylate (USAN) |
D10396 |
UGT |
|
|
| Nirmatrelvir and ritonavir |
D12269 |
CYP3A4 |
CYP3A |
|
| Nirogacestat (USAN/INN) |
D10960 |
CYP3A4; CYP2C19, CYP2C9, CYP2D6 |
|
|
| Nirogacestat hydrobromide (USAN) |
D11453 |
CYP3A4; CYP2C19, CYP2C9, CYP2D6 |
|
|
| Nisoldipine (JAN/USAN/INN) |
D00618 |
CYP3A4 |
|
|
| Nitisinone (JAN/USAN/INN) |
D05177 |
|
CYP2C9 |
|
| Nitrendipine (JP18/USAN/INN) |
D00629 |
CYP3A4 |
|
|
| Noradrenaline (JP18) |
D00076 |
COMT, MAO |
|
|
| Nordazepam (INN) |
D08283 |
CYP2C19, CYP3A4 |
|
|
| Norepinephrine bitartrate (USP) |
D05206 |
COMT, MAO |
|
|
| Norepinephrine hydrochloride (JAN) |
D09794 |
COMT, MAO |
|
|
| Norepinephrine hydrochoride |
D08284 |
COMT, MAO |
|
|
| Norfloxacin (JP18/USP/INN) |
D00210 |
CYP1A2 |
CYP3A, CYP1A2 |
|
| Norfloxacin nicotinate |
D08287 |
CYP1A2 |
CYP3A, CYP1A2 |
|
| Norgestrel and ethinylestradiol tablets (JP18) |
D04463 |
CYP3A4, CYP2C9, CYP2C19 |
|
|
| Nortriptyline (INN) |
D08288 |
CYP2D6 |
|
|
| Nortriptyline hydrochloride (JP18/USP/INN) |
D00816 |
CYP2D6 |
|
|
| Ofloxacin (JP18/USP/INN) |
D00453 |
CYP3A4 |
|
|
| Ofloxacin hydrochloride |
D08291 |
CYP3A4 |
|
|
| Olanzapine (JAN/USP/INN) |
D00454 |
CYP1A2; CYP2D6 |
|
|
| Olanzapine pamoate (USAN) |
D06623 |
CYP1A2; CYP2D6 |
|
|
| Olaparib (JAN/USAN/INN) |
D09730 |
CYP3A |
|
|
| Olmesartan medoxomil and azelnidipine |
D09594 |
CYP3A4 |
|
|
| Olodaterol (USAN/INN) |
D10145 |
CYP2C9, CYP2C8, UGT2B7, UGT1A1, UGT1A7, UGT1A9 |
|
|
| Olodaterol hydrochloride (JAN/USAN) |
D10020 |
CYP2C9, CYP2C8, UGT2B7, UGT1A1, UGT1A7, UGT1A9 |
|
|
| Olutasidenib (USAN/INN) |
D12483 |
CYP3A4 |
|
|
| Omaveloxolone (USAN/INN) |
D10964 |
CYP3A; CYP2C8, CYP2J2 |
|
|
| Ombitasvir, paritaprevir and ritonavir |
D10745 |
CYP3A4, CYP3A5 |
CYP3A4 |
|
| Omeprazole (JP18/USP/INN) |
D00455 |
CYP2C19; CYP3A4 |
|
|
| Omeprazole and sodium bicarbonate |
D11706 |
CYP2C19; CYP3A4 |
|
|
| Omeprazole magnesium (USP) |
D05259 |
CYP2C19; CYP3A4 |
|
|
| Omeprazole magnesium, amoxicillin and rifabutin |
D11858 |
CYP3A, CYP2C19 |
CYP2C19 |
CYP3A |
| Omeprazole sodium (USAN) |
D01207 |
CYP2C19; CYP3A4 |
|
|
| Omeprazole sodium injection (JAN) |
D05261 |
CYP2C19; CYP3A4 |
|
|
| Omeprazole, clarithromycin and amoxicillin |
D10246 |
CYP2C19, CYP3A4 |
CYP3A4 |
|
| Omidenepag (USAN/INN) |
D10965 |
CES1 |
|
|
| Omidenepag isopropyl (JAN) |
D10966 |
CES1 |
|
|
| Ondansetron (JAN/USP/INN) |
D00456 |
CYP1A2, CYP3A4, CYP2D6 |
|
|
| Ondansetron hydrochloride hydrate (JAN/USP) |
D00678 |
CYP1A2, CYP2D6, CYP3A4 |
|
|
| Opicapone (JAN/USAN/INN) |
D10825 |
|
COMT |
|
| Osilodrostat (USAN/INN) |
D11061 |
CYP3A4, CYP2B6, CYP2D6, UGT |
|
|
| Osilodrostat phosphate (JAN/USAN) |
D11062 |
CYP3A4, CYP2B6, CYP2D6, UGT |
|
|
| Osimertinib mesylate (USAN) |
D10766 |
CYP3A |
|
|
| Oxcarbazepine (JAN/USP/INN) |
D00533 |
|
CYP2C19 |
CYP3A |
| Oxtriphylline (USP) |
D02017 |
CYP1A2 |
|
|
| Oxybutynin (USAN/INN) |
D00465 |
CYP3A4, CYP3A5 |
|
|
| Oxybutynin chloride (USP) |
D00722 |
CYP3A4, CYP3A5 |
|
|
| Oxycodone (USAN/INN) |
D05312 |
CYP3A4; CYP2D6 |
|
|
| Oxycodone and ibuprofen |
D11573 |
CYP3A4, CYP2A6 |
|
|
| Oxycodone hydrochloride (USP) |
D00847 |
CYP3A4; CYP2D6 |
|
|
| Oxycodone hydrochloride hydrate (JP18) |
D05462 |
CYP3A4; CYP2D6 |
|
|
| Oxycodone terephthalate (USP) |
D03783 |
CYP3A4; CYP2D6 |
|
|
| Ozenoxacin (JAN/USAN/INN) |
D09544 |
CYP3A4 |
|
|
| Paclitaxel (JAN/USP/INN) |
D00491 |
CYP2C8, CYP3A4 |
|
|
| Paclitaxel poliglumex (USAN/INN) |
D05333 |
CYP2C8, CYP3A4 |
|
|
| Pacritinib (USAN/INN) |
D11768 |
CYP3A4 |
|
|
| Palonosetron (INN) |
D07175 |
CYP1A2, CYP2D6, CYP3A4 |
|
|
| Palonosetron hydrochloride (JAN/USP) |
D05343 |
CYP1A2, CYP2D6, CYP3A4 |
|
|
| Palovarotene (JAN/USAN/INN) |
D09365 |
CYP3A4; CYP2C8, CYP2C19 |
|
|
| Panobinostat (USAN/INN) |
D10319 |
CYP3A4 |
CYP2D6 |
|
| Panobinostat lactate (JAN) |
D10019 |
CYP3A4 |
CYP2D6 |
|
| Pantoprazole (USAN/INN) |
D05353 |
CYP2C19; CYP3A4 |
|
|
| Pantoprazole sodium (USP) |
D02593 |
CYP2C19; CYP3A4 |
|
|
| Paroxetine (USP/INN) |
D02362 |
CYP2D6 |
CYP2D6 |
|
| Paroxetine hydrochloride (USP) |
D05374 |
CYP2D6 |
CYP2D6 |
|
| Paroxetine hydrochloride hemihydrate (USP) |
D02260 |
CYP2D6 |
CYP2D6 |
|
| Paroxetine mesylate (USAN) |
D05375 |
CYP2D6 |
CYP2D6 |
|
| Pazufloxacin (JAN/INN) |
D01153 |
|
CYP1A2 |
|
| Pazufloxacin mesilate (JP18) |
D05382 |
|
CYP1A2 |
|
| Peginterferon alfa-2b (USAN/INN) |
D02748 |
|
CYP1A2, CYP2D6 |
|
| Pemafibrate (JAN) |
D10711 |
CYP3A, CYP2C9, CYP2C8 |
|
|
| Pemigatinib (JAN/USAN/INN) |
D11417 |
CYP3A4 |
|
|
| Perampanel (USAN) |
D08964 |
CYP3A |
|
|
| Perampanel hydrate (JAN) |
D10780 |
CYP3A |
|
|
| Perhexiline (INN) |
D08340 |
CYP2D6 |
|
|
| Perhexiline maleate (USAN) |
D05442 |
CYP2D6 |
|
|
| Perphenazine (JP18/USP/INN) |
D00503 |
CYP2D6 |
|
|
| Perphenazine decanoate |
D08341 |
CYP2D6 |
|
|
| Perphenazine enantate |
D08342 |
CYP2D6 |
|
|
| Perphenazine fendizoate (JAN) |
D04038 |
CYP2D6 |
|
|
| Perphenazine hydrochloride |
D04965 |
CYP2D6 |
|
|
| Perphenazine maleate (JP18) |
D02037 |
CYP2D6 |
|
|
| Pexidartinib (USAN/INN) |
D11270 |
CYP3A4, UGT1A4 |
|
|
| Pexidartinib hydrochloride (JAN/USAN) |
D11271 |
CYP3A4, UGT1A4 |
|
|
| Phenformin (BAN) |
D08351 |
CYP2D6 |
|
|
| Phenformin hydrochloride |
D08352 |
CYP2D6 |
|
|
| Phenobarbital (JP18/USP/INN) |
D00506 |
|
|
CYP3A; CYP1A2, CYP2B6, CYP2C9 |
| Phenobarbital diethylamine |
D08356 |
|
|
CYP3A; CYP1A2, CYP2B6, CYP2C9 |
| Phenobarbital sodium (JAN/USP/INN) |
D00701 |
|
|
CYP3A; CYP1A2, CYP2B6, CYP2C9 |
| Phentermine and topiramate |
D11710 |
CYP3A4 |
|
|
| Phenylbutazone (JP18/USP/INN) |
D00510 |
|
CYP2C9 |
|
| Phenylbutazone calcium |
D08363 |
|
CYP2C9 |
|
| Phenylbutazone sodium |
D08364 |
|
CYP2C9 |
|
| Phenylpropanolamine (INN) |
D08368 |
|
CYP1A2 |
|
| Phenylpropanolamine hydrochloride (JAN/USP) |
D01224 |
|
CYP1A2 |
|
| Phenylpropanolamine polistirex (USAN) |
D05466 |
|
CYP1A2 |
|
| Phenytoin (JP18/USP/INN) |
D00512 |
CYP2C9; CYP2C19 |
|
CYP3A, CYP2B6 |
| Phenytoin and phenobarbital |
D07583 |
CYP2C9; CYP2C19 |
|
CYP3A, CYP2B6 |
| Phenytoin sodium (USP) |
D02103 |
CYP2C9; CYP2C19 |
|
CYP3A, CYP2B6 |
| Phenytoin, phenobarbital and caffeine and sodium benzoate |
D03844 |
CYP2C9, CYP2C19, CYP2B6, CYP3A |
|
|
| Pilocarpine (JAN/USP) |
D00525 |
CYP2A6 |
|
|
| Pilocarpine borate |
D08376 |
CYP2A6 |
|
|
| Pilocarpine hydrochloride (JP18/USP) |
D02200 |
CYP2A6 |
|
|
| Pilocarpine nitrate (USP) |
D05478 |
CYP2A6 |
|
|
| Pimavanserin tartrate (USAN) |
D08969 |
CYP3A4, CYP3A5; CYP2J2, CYP2D6 |
|
|
| Pimitespib (JAN) |
D11920 |
|
CYP3A |
|
| Pimozide (JP18/USP/INN) |
D00560 |
CYP3A4; CYP2D6 |
|
|
| Pindolol (JP18/USP/INN) |
D00513 |
CYP2D6 |
|
|
| Pioglitazone (INN) |
D08378 |
CYP2C8 |
|
|
| Pioglitazone hydrochloride (JP18/USP) |
D00945 |
CYP2C8 |
|
|
| Pioglitazone hydrochloride and glimepiride tablets (JP18) |
D09848 |
CYP2C8, CYP2C9 |
|
|
| Pipemidic acid (INN) |
D08379 |
|
CYP1A2 |
|
| Pipemidic acid hydrate (JP18) |
D01531 |
|
CYP1A2 |
|
| Pirfenidone (JAN/USAN/INN) |
D01583 |
CYP1A2; CYP2C9, CYP2C19, CYP2D6, CYP2E1 |
|
|
| Piroxicam (JP18/USP/INN) |
D00127 |
CYP2C9 |
|
|
| Piroxicam betadex (USAN) |
D05511 |
CYP2C9 |
|
|
| Piroxicam cinnamate (USAN) |
D05512 |
CYP2C9 |
|
|
| Piroxicam olamine (USAN) |
D05513 |
CYP2C9 |
|
|
| Pirtobrutinib (JAN/USAN) |
D12050 |
CYP3A4 |
CYP2C8, CYP2C19, CYP3A |
|
| Pitavastatin calcium (JAN) |
D01862 |
CYP2C9 |
|
|
| Pitavastatin calcium hydrate (JP18) |
D10568 |
CYP2C9 |
|
|
| Pitavastatin magnesium |
D11092 |
CYP2C9 |
|
|
| Pitolisant (USAN/INN) |
D10749 |
CYP2D6; CYP3A4 |
|
|
| Pitolisant hydrochloride (USAN) |
D11490 |
CYP2D6; CYP3A4 |
|
|
| Platycodon fluidextract, glycyrrhiza extract, plantago herb extract, peony root extract and dihydrocodeine phosphate |
D08697 |
UGT2B7, UGT2B4; CYP3A4, CYP2D6 |
|
|
| Polatuzumab vedotin (USAN) |
D10761 |
CYP3A |
|
|
| Pomalidomide (JAN/USAN/INN) |
D08976 |
CYP1A2, CYP3A4 |
|
|
| Ponatinib (USAN/INN) |
D09950 |
CYP3A |
|
|
| Ponatinib hydrochloride (JAN/USAN) |
D09951 |
CYP3A |
|
|
| Posaconazole (JAN/USAN/INN) |
D02555 |
|
CYP3A4 |
|
| Pranlukast (INN) |
D08408 |
CYP3A4 |
|
|
| Pranlukast hydrate (JP18) |
D02732 |
CYP3A4 |
|
|
| Praziquantel (JAN/USP/INN) |
D00471 |
CYP3A4 |
|
|
| Prednisolone (JP18/USP/INN) |
D00472 |
CYP3A |
|
|
| Procainamide (INN) |
D08421 |
NAT |
|
|
| Procainamide hydrochloride (JP18/USP) |
D00477 |
NAT |
|
|
| Procaterol (INN) |
D08424 |
CYP3A4 |
|
|
| Procaterol hydrochloride (USAN) |
D02404 |
CYP3A4 |
|
|
| Procaterol hydrochloride hydrate (JP18) |
D05366 |
CYP3A4 |
|
|
| Progesterone (JP18/USP/INN) |
D00066 |
CYP3A4, CYP2C19 |
|
|
| Proguanil (INN) |
D08428 |
CYP2C19 |
|
|
| Proguanil hydrochloride (JAN/USP) |
D02487 |
CYP2C19 |
|
|
| Promethazine (JAN/INN) |
D00494 |
CYP2D6 |
|
|
| Promethazine hibenzate |
D08768 |
CYP2D6 |
|
|
| Promethazine hydrochloride (JP18/USP) |
D00480 |
CYP2D6 |
|
|
| Promethazine maleate |
D08432 |
CYP2D6 |
|
|
| Promethazine methylenedisalicylate (JAN) |
D03290 |
CYP2D6 |
|
|
| Promethazine teoclate (JAN/INN) |
D01242 |
CYP2D6 |
|
|
| Propafenone (INN) |
D08435 |
CYP2D6, CYP3A4, CYP1A2 |
|
|
| Propafenone hydrochloride (JP18/USP) |
D00640 |
CYP2D6, CYP3A4, CYP1A2 |
|
|
| Propiverine (INN) |
D08441 |
CYP3A4 |
|
|
| Propiverine hydrochloride (JP18) |
D01007 |
CYP3A4 |
|
|
| Propranolol (INN) |
D08443 |
CYP2D6, CYP1A2, CYP2C19 |
|
|
| Propranolol hydrochloride (JP18/USP) |
D00483 |
CYP2D6, CYP1A2, CYP2C19 |
|
|
| Proxyphylline, ephedrine hydrochloride and phenobarbital |
D04307 |
|
|
CYP3A |
| Quazepam (JAN/USP/INN) |
D00457 |
CYP2C9, CYP3A4 |
|
|
| Quetiapine (INN) |
D08456 |
CYP3A4 |
|
|
| Quetiapine fumarate (JP18/USP) |
D00458 |
CYP3A4 |
|
|
| Quinine (BAN) |
D08460 |
CYP3A4 |
|
|
| Quinine ascorbate (USAN) |
D05681 |
CYP3A4 |
|
|
| Quinine dihydrochloride |
D08461 |
CYP3A4 |
|
|
| Quinine ethylcarbonate (JP18) |
D01663 |
CYP3A4 |
|
|
| Quinine hydrochloride hydrate (JP18) |
D02261 |
CYP3A4 |
|
|
| Quinine sulfate (USP) |
D02262 |
CYP3A4 |
|
|
| Quinupristin and dalfopristin |
D00854 |
|
CYP3A4 |
|
| Quizartinib (USAN/INN) |
D09955 |
CYP3A |
|
|
| Quizartinib dihydrochloride (USAN) |
D09956 |
CYP3A |
|
|
| Rabeprazole (INN) |
D08463 |
CYP2C19, CYP3A4 |
|
|
| Rabeprazole sodium (JP18/USP) |
D00724 |
CYP2C19, CYP3A4 |
|
|
| Rabeprazole, amoxicillin and clarithromycin |
D10519 |
CYP2C19, CYP3A4 |
CYP3A4 |
|
| Rabeprazole, amoxicillin and metronidazole |
D10520 |
CYP2C19, CYP3A4 |
|
|
| Raltegravir (INN) |
D06676 |
UGT1A1 |
|
|
| Raltegravir potassium (JAN/USAN) |
D07133 |
UGT1A1 |
|
|
| Ramelteon (JAN/USAN/INN) |
D02689 |
CYP1A2 |
|
|
| Ramosetron (INN) |
D08466 |
CYP1A2, CYP2D6 |
|
|
| Ramosetron hydrochloride (JAN) |
D02016 |
CYP1A2, CYP2D6 |
|
|
| Ranitidine (USAN/INN) |
D00422 |
|
CYP2D6, CYP3A |
|
| Ranitidine bismuth citrate (USAN) |
D05699 |
|
CYP2D6, CYP3A |
|
| Ranitidine hydrochloride (JP18/USP) |
D00673 |
|
CYP2D6, CYP3A |
|
| Ranolazine (USAN/INN) |
D05700 |
CYP3A |
CYP2D6 |
|
| Ranolazine hydrochloride (USAN) |
D05701 |
CYP3A |
CYP2D6 |
|
| Rasagiline (USAN/INN) |
D08469 |
CYP1A2 |
|
|
| Rasagiline mesylate (USAN) |
D02562 |
CYP1A2 |
|
|
| Rasagiline tartrate |
D10829 |
CYP1A2 |
|
|
| Ravuconazole (prop.INN) |
D02556 |
|
CYP3A |
|
| Rebamipide (JP18/INN) |
D01121 |
CYP3A4 |
|
|
| Regorafenib (USAN/INN) |
D10138 |
CYP3A4, UGT1A9 |
|
|
| Regorafenib hydrate (JAN) |
D10137 |
CYP3A4, UGT1A9 |
|
|
| Repaglinide (JAN/USP/INN) |
D00594 |
CYP2C8; CYP3A4 |
|
|
| Repotrectinib (JAN/USAN) |
D11454 |
CYP3A4 |
|
|
| Retinol acetate (JP18) |
D01621 |
CYP2C8 |
|
|
| Retinol palmitate (JP18) |
D00164 |
CYP2C8 |
|
|
| Retinol propionate |
D08477 |
CYP2C8 |
|
|
| Ribociclib (USAN/INN) |
D10883 |
CYP3A4 |
|
|
| Ribociclib succinate (USAN) |
D10979 |
CYP3A4 |
|
|
| Rifabutin (JAN/USP/INN) |
D00424 |
CYP3A4 |
|
CYP3A |
| Rifampicin sodium |
D08479 |
|
|
CYP3A4, UGT |
| Rifampin (USP) |
D00211 |
|
|
CYP3A4, UGT |
| Rifapentine (USAN/INN) |
D00879 |
|
|
CYP3A4, CYP2C8, CYP2C9 |
| Rifaximin (JAN/USAN/INN) |
D02554 |
CYP3A4 |
|
CYP3A4 |
| Rilmazafone (INN) |
D08481 |
CES, CYP3A4 |
|
|
| Rilmazafone hydrochloride hydrate (JP18) |
D01564 |
CES, CYP3A4 |
|
|
| Rilpivirine (JAN/USAN/INN) |
D09720 |
CYP3A |
|
|
| Rilpivirine hydrochloride (JAN/USAN) |
D09958 |
CYP3A |
|
|
| Rilpivirine hydrochloride, tenofovir disoproxil fumarate and emtricitabine |
D10571 |
CYP3A |
|
|
| Riluzole (JAN/USP/INN) |
D00775 |
CYP1A2 |
|
|
| Rimegepant (USAN/INN) |
D10662 |
CYP3A4; CYP2C9 |
|
|
| Rimegepant sulfate (USAN) |
D10663 |
CYP3A4; CYP2C9 |
|
|
| Riociguat (JAN/USAN/INN) |
D09572 |
CYP1A1, CYP2C8, CYP2J2, CYP3A |
|
|
| Risdiplam (JAN/USAN/INN) |
D11406 |
FMO1, FMO3, CYP1A1, CYP2J2, CYP3A4, CYP3A7 |
|
|
| Risperidone (JP18/USP/INN) |
D00426 |
CYP2D6, CYP3A4 |
|
|
| Ritlecitinib tosylate (USAN) |
D11970 |
|
CYP3A, CYP1A2 |
|
| Ritonavir (JAN/USP/INN) |
D00427 |
CYP3A, CYP2D6 |
CYP3A |
CYP1A2, CYP2C9, CYP2C19 |
| Rivaroxaban (JAN/USAN/INN) |
D07086 |
CYP3A4, CYP2J2 |
|
|
| Roflumilast (JAN/USAN/INN) |
D05744 |
CYP3A4, CYP1A2 |
|
|
| Rolapitant (USAN/INN) |
D10742 |
CYP3A4 |
CYP2D6 |
|
| Rolapitant hydrochloride (USAN) |
D08988 |
CYP3A4 |
CYP2D6 |
|
| Romidepsin (JAN/USAN/INN) |
D06637 |
CYP3A |
|
|
| Ropinirole (USAN/INN) |
D08489 |
CYP1A2 |
|
|
| Ropinirole hydrochloride (JAN/USP) |
D00784 |
CYP1A2 |
|
|
| Ropivacaine (INN) |
D08490 |
CYP1A2, CYP3A4 |
|
|
| Ropivacaine hydrochloride (USP) |
D04048 |
CYP1A2, CYP3A4 |
|
|
| Roxadustat (JAN/USAN/INN) |
D10593 |
CYP2C8, UGT1A9 |
|
|
| Roxithromycin (JP18/USAN/INN) |
D01710 |
CYP3A |
|
|
| Rufinamide (JAN/USP/INN) |
D05775 |
CES |
|
|
| Rupatadine (INN) |
D07407 |
CYP3A4 |
|
|
| Rupatadine fumarate (JAN) |
D08497 |
CYP3A4 |
|
|
| Ruxolitinib (USAN/INN) |
D09959 |
CYP3A4; CYP2C9 |
|
|
| Ruxolitinib phosphate (JAN/USAN) |
D09960 |
CYP3A4; CYP2C9 |
|
|
| Safinamide (USAN/INN) |
D10158 |
MAOA; CYP3A4 |
|
|
| Safinamide mesylate (USAN) |
D10191 |
MAOA; CYP3A4 |
|
|
| Salmeterol (USAN/INN) |
D05792 |
CYP3A4 |
|
|
| Salmeterol xinafoate (JAN/USP) |
D00687 |
CYP3A4 |
|
|
| Salmeterol xinafoate and fluticasone propionate |
D08699 |
CYP3A4 |
|
|
| Saquinavir (JAN/USP/INN) |
D00429 |
CYP3A4 |
|
|
| Saquinavir mesylate (USP) |
D01160 |
CYP3A4 |
|
|
| Sarpogrelate (INN) |
D08508 |
CYP1A2, CYP2B6, CYP2C9, CYP2C19, CYP2D6, CYP3A4 |
|
|
| Sarpogrelate hydrochloride (JP18) |
D01624 |
CYP1A2, CYP2B6, CYP2C9, CYP2C19, CYP2D6, CYP3A4 |
|
|
| Saxagliptin (USAN/INN) |
D08996 |
CYP3A4, CYP3A5 |
|
|
| Saxagliptin hydrate (JAN) |
D09753 |
CYP3A4, CYP3A5 |
|
|
| Saxagliptin hydrochloride |
D10262 |
CYP3A4, CYP3A5 |
|
|
| Selegiline (USAN/INN) |
D03731 |
CYP2B6, CYP2D6, CYP3A4; CYP2A6 |
|
|
| Selegiline hydrochloride (JAN/USP) |
D00785 |
CYP2B6, CYP2D6, CYP3A4; CYP2A6 |
|
|
| Selexipag (JAN/USAN/INN) |
D09994 |
CYP2C8, CYP3A4, UGT1A3, UGT2B7 |
|
|
| Selinexor (USAN/INN) |
D11222 |
CYP3A4, UGT, GST |
|
|
| Selpercatinib (JAN/USAN/INN) |
D11713 |
CYP3A4 |
|
|
| Selumetinib (USAN/INN) |
D09666 |
CYP3A4, UGT1A1, UGT1A3; CYP2C19, CYP1A2, CYP2C9, CYP2E1, CYP3A5 |
|
|
| Selumetinib sulfate (JAN/USAN) |
D10024 |
CYP3A4, UGT1A1, UGT1A3; CYP2C19, CYP1A2, CYP2C9, CYP2E1, CYP3A5 |
|
|
| Sertraline (INN) |
D02360 |
CYP2C19, CYP2C9, CYP2B6, CYP3A4 |
|
|
| Sertraline hydrochloride (JAN/USP) |
D00825 |
CYP2C19, CYP2C9, CYP2B6, CYP3A4 |
|
|
| Sildenafil (INN) |
D08514 |
CYP3A4; CYP2C9 |
|
|
| Sildenafil citrate (JAN/USP) |
D02229 |
CYP3A4; CYP2C9 |
|
|
| Silodosin (JP18/INN) |
D01965 |
CYP3A4, UGT |
|
|
| Simeprevir (JAN/USAN) |
D10081 |
CYP3A |
CYP3A |
|
| Simeprevir sodium (JAN) |
D10469 |
CYP3A |
CYP3A |
|
| Simvastatin (JP18/USP/INN) |
D00434 |
CYP3A4 |
|
|
| Siponimod (USAN/INN) |
D11460 |
CYP2C9; CYP3A4 |
|
|
| Siponimod fumarate (USAN) |
D11072 |
CYP2C9; CYP3A4 |
|
|
| Sirolimus (JAN/USAN/INN) |
D00753 |
CYP3A4 |
CYP3A4 |
|
| Sitagliptin and ipragliflozin |
D11064 |
UGT2B7 |
|
|
| Sodium aceneuramate (JAN) |
D09855 |
NPL |
|
|
| Sofosbuvir and velpatasvir |
D10827 |
CYP2B6, CYP2C8, CYP3A4 |
|
|
| Sofpironium bromide (JAN/USAN/INN) |
D10989 |
CYP2D6, CYP3A4 |
|
|
| Solifenacin (INN) |
D08522 |
CYP3A4 |
|
|
| Solifenacin succinate (JAN/USAN/INN) |
D01269 |
CYP3A4 |
|
|
| Somatropin (USP/INN) |
D02691 |
|
CYP2C19 |
|
| Sonidegib (USAN/INN) |
D10119 |
CYP3A |
|
|
| Sonidegib phosphate (USAN) |
D10729 |
CYP3A |
|
|
| Sotagliflozin (USAN/INN) |
D10669 |
UGT1A9; CYP3A4 |
|
|
| Sotorasib (JAN/USAN) |
D12055 |
CYP3A |
|
|
| Sparsentan (USAN/INN) |
D11776 |
CYP3A |
|
|
| Sparteine (INN) |
D01041 |
CYP2D6 |
|
|
| Sparteine sulfate (JAN/USAN) |
D02239 |
CYP2D6 |
|
|
| Stiripentol (JAN/USAN/INN) |
D05928 |
CYP1A2, CYP2C19, CYP3A4 |
CYP1A2, CYP3A4, CYP2D6, CYP2C19, CYP2C9 |
|
| Sumatriptan (JAN/USP/INN) |
D00451 |
MAOA |
|
|
| Sumatriptan succinate (JAN/USP) |
D00676 |
MAOA |
|
|
| Sunitinib (INN) |
D08552 |
CYP3A4 |
|
|
| Sunitinib malate (JAN/USAN) |
D06402 |
CYP3A4 |
|
|
| Suprofen (JAN/USP/INN) |
D00452 |
CYP2C9 |
|
|
| Suvorexant (JAN/USAN) |
D10082 |
CYP3A; CYP2C19 |
|
|
| Synthetic conjugated estrogens, B (USAN) |
D05987 |
CYP3A4 |
|
|
| Tacrine (INN) |
D08555 |
CYP1A2 |
|
|
| Tacrine hydrochloride (USP) |
D02068 |
CYP1A2 |
|
|
| Tacrolimus (INN) |
D08556 |
CYP3A4 |
|
|
| Tacrolimus (USP/INN) |
D00107 |
CYP3A4 |
|
|
| Tadalafil (JAN/USP/INN) |
D02008 |
CYP3A4 |
|
|
| Tamibarotene (JAN/USAN/INN) |
D01418 |
CYP3A4 |
|
|
| Tamoxifen (INN) |
D08559 |
CYP2D6, CYP3A4 |
|
|
| Tamoxifen citrate (JP18/USP) |
D00966 |
CYP2D6, CYP3A4 |
|
|
| Tapentadol (USAN/INN) |
D06007 |
UGT |
|
|
| Tapentadol hydrochloride (JAN) |
D10199 |
UGT |
|
|
| Tasimelteon (USAN/INN) |
D09388 |
CYP3A4, CYP1A2 |
|
|
| Tecovirimat (USAN/INN) |
D09390 |
UGT1A1, UGT1A4 |
|
|
| Tecovirimat hydrate (JAN) |
D11557 |
UGT1A1, UGT1A4 |
|
|
| Tegafur (JP18/USAN/INN) |
D01244 |
CYP2A6 |
|
|
| Tegaserod (USAN/INN) |
D06056 |
UGT |
|
|
| Tegaserod maleate (USAN) |
D02730 |
UGT |
|
|
| Telaprevir (JAN/USAN/INN) |
D09012 |
CYP3A4 |
CYP3A4, CYP3A5 |
|
| Telithromycin (JAN/USAN/INN) |
D01078 |
CYP3A, CYP2D6 |
CYP3A, CYP2D6 |
|
| Telmisartan (JP18/USP/INN) |
D00627 |
UGT |
|
|
| Telmisartan and amlodipine besilate (JP18) |
D09743 |
CYP3A4, UGT |
|
|
| Telmisartan and hydrochlorothiazide (JP18) |
D09219 |
UGT |
|
|
| Telmisartan, amlodipine and hydrochlorothiazide |
D10805 |
CYP3A4, UGT |
|
|
| Temsavir (USAN/INN) |
D10734 |
CYP3A |
|
|
| Temsirolimus (JAN/USAN/INN) |
D06068 |
CYP3A4 |
|
|
| Tenapanor (USAN/INN) |
D11652 |
CYP3A4, CYP3A5 |
|
|
| Tenapanor hydrochloride (JAN/USAN) |
D11653 |
CYP3A4, CYP3A5 |
|
|
| Teneligliptin (INN) |
D08616 |
CYP3A4, FMO1, FMO3 |
CYP2D6, CYP3A4, FMO |
|
| Teneligliptin and canagliflozin |
D10897 |
CYP3A4, FMO1, FMO3, UGT1A9, UGT2B4 |
|
|
| Teneligliptin hydrobromide (JAN) |
D11968 |
CYP3A4, FMO1, FMO3 |
CYP2D6, CYP3A4, FMO |
|
| Teneligliptin hydrobromide hydrate (JAN) |
D09756 |
CYP3A4, FMO1, FMO3 |
CYP2D6, CYP3A4, FMO |
|
| Tenoxicam (JAN/USAN/INN) |
D01767 |
CYP2C9 |
|
|
| Tepotinib (USAN/INN) |
D11717 |
CYP3A4, CYP2C8 |
|
|
| Tepotinib hydrochloride (USAN) |
D11073 |
CYP3A4, CYP2C8 |
|
|
| Terbinafine (USAN/INN) |
D02375 |
CYP2C9, CYP1A2, CYP3A4, CYP2C8, CYP2C19 |
CYP2D6 |
|
| Terbinafine hydrochloride (JP18/USP) |
D02219 |
CYP2C9, CYP1A2, CYP3A4, CYP2C8, CYP2C19 |
CYP2D6 |
|
| Terfenadine (JAN/USAN/INN) |
D00521 |
CYP3A |
|
|
| Tetrabenazine (JAN/INN) |
D08575 |
CYP2D6; CYP3A4, CYP1A2, CBR |
|
|
| Theophylline (JP18) |
D00371 |
CYP1A2 |
|
|
| Theophylline (USP) |
D06103 |
CYP1A2 |
|
|
| Theophylline sodium acetate (JAN) |
D01712 |
CYP1A2 |
|
|
| Theophylline sodium glycinate (USP) |
D06104 |
CYP1A2 |
|
|
| Ticagrelor (JAN/USAN/INN) |
D09017 |
CYP3A |
CYP3A |
|
| Ticlopidine (INN) |
D08594 |
|
CYP2C19, CYP1A2, CYP2B6, CYP2D6 |
|
| Ticlopidine hydrochloride (JP18/USP) |
D01028 |
|
CYP2C19, CYP1A2, CYP2B6, CYP2D6 |
|
| Timolol (INN) |
D08600 |
CYP2D6 |
|
|
| Timolol (USAN) |
D00378 |
CYP2D6 |
|
|
| Timolol maleate (JP18/USP) |
D00603 |
CYP2D6 |
|
|
| Tiotropium and olodaterol |
D10744 |
UGT |
|
|
| Tivozanib (USAN/INN) |
D09683 |
CYP3A4 |
|
|
| Tivozanib hydrochloride (USAN) |
D10190 |
CYP3A4 |
|
|
| Tizanidine (INN) |
D08611 |
CYP1A2 |
|
|
| Tizanidine hydrochloride (JP18/USP) |
D00776 |
CYP1A2 |
|
|
| Tofacitinib (USAN) |
D09970 |
CYP3A4; CYP2C19 |
|
|
| Tofacitinib citrate (JAN/USAN) |
D09783 |
CYP3A4; CYP2C19 |
|
|
| Tofogliflozin (USAN) |
D09978 |
CYP2C18, CYP4A11, CYP4F3 |
|
|
| Tolcapone (JAN/USP/INN) |
D00786 |
|
COMT |
|
| Tolterodine (USAN/INN) |
D00646 |
CYP2D6, CYP3A4 |
|
|
| Tolterodine tartrate (JAN/USP) |
D01148 |
CYP2D6, CYP3A4 |
|
|
| Tolvaptan (JAN/USAN/INN) |
D01213 |
CYP3A4 |
|
|
| Topiramate (JAN/USP/INN) |
D00537 |
CYP3A4 |
|
|
| Torasemide sodium |
D08619 |
CYP2C9, CYP2C8 |
|
|
| Toremifene (INN) |
D08620 |
CYP3A4 |
|
|
| Toremifene citrate (JAN/USAN) |
D00967 |
CYP3A4 |
|
|
| Torsemide (USP) |
D00382 |
CYP2C9, CYP2C8 |
|
|
| Trabectedin (JAN/USAN/INN) |
D06199 |
CYP3A4 |
|
|
| Tramadol (INN) |
D08623 |
CYP2D6, CYP3A4 |
|
|
| Tramadol hydrochloride (JP18/USP) |
D01355 |
CYP2D6, CYP3A4 |
|
|
| Tramadol hydrochloride and acetaminophen |
D09999 |
CYP2D6, CYP3A4 |
|
|
| Tranilast (JP18/USAN/INN) |
D02027 |
CYP2C9 |
|
|
| Trazodone (INN) |
D08626 |
CYP3A4, CYP2D6 |
|
|
| Trazodone hydrochloride (JAN/USP) |
D00820 |
CYP3A4, CYP2D6 |
|
|
| Trelagliptin (USAN) |
D10178 |
CYP2D6 |
|
|
| Trelagliptin succinate (JAN/USAN) |
D10179 |
CYP2D6 |
|
|
| Treprostinil (JAN/USAN/INN) |
D06213 |
CYP2C8 |
|
|
| Treprostinil diolamine (USAN) |
D10430 |
CYP2C8 |
|
|
| Treprostinil monosodium salt |
D08628 |
CYP2C8 |
|
|
| Treprostinil palmitil (USAN/INN) |
D12005 |
CYP2C8 |
|
|
| Treprostinil phosphate (USAN) |
D12629 |
CYP2C8 |
|
|
| Triazolam (JP18/USP/INN) |
D00387 |
CYP3A4 |
|
|
| Trimethoprim (JAN/USP/INN) |
D00145 |
|
CYP2C8 |
|
| Trimethoprim hydrochloride |
D11085 |
|
CYP2C8 |
|
| Trimethoprim lactate |
D08644 |
|
CYP2C8 |
|
| Trimethoprim sulfate (USP) |
D06236 |
|
CYP2C8 |
|
| Tripelennamine (INN) |
D08645 |
|
CYP2D6 |
|
| Tripelennamine citrate |
D06246 |
|
CYP2D6 |
|
| Tripelennamine hydrochloride (USP) |
D02091 |
|
CYP2D6 |
|
| Troglitazone (JAN/USAN/INN) |
D00395 |
|
|
CYP3A |
| Troleandomycin (USAN/INN) |
D01322 |
CYP3A4 |
CYP3A4 |
|
| Tucatinib (USAN/INN) |
D11141 |
CYP2C8; CYP3A |
|
|
| Tucatinib ethanolate (JAN) |
D12442 |
CYP2C8; CYP3A |
|
|
| Ubrogepant (USAN/INN) |
D10673 |
CYP3A4 |
|
|
| Umeclidinium (USAN) |
D10180 |
CYP2D6 |
|
|
| Umeclidinium bromide (JAN/USAN) |
D10181 |
CYP2D6 |
|
|
| Umeclidinium bromide and vilanterol |
D10533 |
CYP2D6, CYP3A4 |
|
|
| Upadacitinib (USAN/INN) |
D10994 |
CYP3A4; CYP2D6 |
|
|
| Upadacitinib hydrate (JAN) |
D11048 |
CYP3A4; CYP2D6 |
|
|
| Upadacitinib tartrate (USAN) |
D10995 |
CYP3A4; CYP2D6 |
|
|
| Urapidil (JP18/INN) |
D01333 |
CYP2D6 |
|
|
| Urapidil hydrochloride |
D08662 |
CYP2D6 |
|
|
| Valbenazine (USAN/INN) |
D10675 |
CYP3A4, CYP3A5; CYP2D6 |
|
|
| Valbenazine tosylate (USAN) |
D10999 |
CYP3A4, CYP3A5; CYP2D6 |
|
|
| Valsartan (JP18/USP/INN) |
D00400 |
CYP2C9 |
|
|
| Valsartan and amlodipine besilate |
D09745 |
CYP3A4 |
|
|
| Valsartan and cilnidipine |
D10525 |
CYP3A4; CYP2C19 |
|
|
| Vamorolone (USAN/INN) |
D11000 |
CYP3A4, CYP3A5, CYP2C8, UGT1A3, UGT2B7, UGT2B17 |
|
|
| Vandetanib (JAN/USAN/INN) |
D06407 |
CYP3A4 |
|
|
| Vaniprevir (JAN/USAN/INN) |
D09987 |
CYP3A |
|
|
| Vardenafil (USAN/INN) |
D08668 |
CYP3A4 |
|
|
| Vardenafil dihydrochoride (USAN) |
D02731 |
CYP3A4 |
|
|
| Vardenafil hydrochloride (USP) |
D09989 |
CYP3A4 |
|
|
| Vardenafil hydrochloride hydrate (JAN) |
D03260 |
CYP3A4 |
|
|
| Vemurafenib (JAN/USAN/INN) |
D09996 |
|
CYP1A2, CYP2C9 |
CYP3A4 |
| Venlafaxine (INN) |
D08670 |
CYP2D6; CYP3A4 |
|
|
| Venlafaxine besylate monohydrate |
D12403 |
CYP2D6; CYP3A4 |
|
|
| Venlafaxine hydrochloride (JAN/USP) |
D00821 |
CYP2D6; CYP3A4 |
|
|
| Verapamil (USAN/INN) |
D02356 |
CYP3A4 |
CYP3A4 |
|
| Verapamil hydrochloride (JP18/USP) |
D00619 |
CYP3A4 |
CYP3A4 |
|
| Vericiguat (JAN/USAN/INN) |
D11051 |
UGT1A9; UGT1A1 |
|
|
| Vibegron (JAN/USAN/INN) |
D10433 |
CYP3A4 |
|
|
| Vilazodone (USAN/INN) |
D09698 |
CYP3A4; CYP2D6, CYP2C19 |
|
|
| Vilazodone hydrochloride (USAN) |
D09699 |
CYP3A4; CYP2D6, CYP2C19 |
|
|
| Viloxazine (INN) |
D08673 |
CYP2D6, UGT1A9, UGT2B15 |
|
|
| Viloxazine hydrochloride (USAN) |
D02572 |
CYP2D6, UGT1A9, UGT2B15 |
|
|
| Vinblastine (INN) |
D08675 |
CYP3A4 |
|
|
| Vinblastine sulfate (JP18/USP) |
D01068 |
CYP3A4 |
|
|
| Vincristine (INN) |
D08679 |
CYP3A |
|
|
| Vincristine sulfate (JP18/USP) |
D02197 |
CYP3A |
|
|
| Vindesine (USAN/INN) |
D06304 |
CYP3A |
|
|
| Vindesine sulfate (JAN/USAN) |
D01769 |
CYP3A |
|
|
| Vinorelbine (INN) |
D08680 |
CYP3A4 |
|
|
| Vinorelbine tartrate (USP) |
D01935 |
CYP3A4 |
|
|
| Vitamin A (USP) |
D06543 |
CYP2C8 |
|
|
| Vitamin A oil (JP18) |
D00069 |
CYP2C8 |
|
|
| Voclosporin (JAN/USAN/INN) |
D09033 |
CYP3A4 |
|
|
| Vonoprazan (USAN/INN) |
D11784 |
CYP3A4; CYP2B6, CYP2C19, CYP2D6 |
|
|
| Vonoprazan and amoxicillin |
D12756 |
CYP3A4, CYP3A5, CYP2B6, CYP2C19, CYP2C9, CYP2D6 |
|
|
| Vonoprazan fumarate (JAN/USAN) |
D10466 |
CYP3A4; CYP2B6, CYP2C19, CYP2D6 |
|
|
| Vonoprazan, amoxicillin and clarithromycin |
D10775 |
CYP3A4; CYP2B6, CYP2C19, CYP2D6 |
CYP3A4 |
|
| Vonoprazan, amoxicillin and metronidazole |
D10774 |
CYP3A4; CYP2B6, CYP2C19, CYP2D6 |
|
|
| Vorapaxar (USAN/INN) |
D09765 |
CYP3A4, CYP2J2 |
|
|
| Vorapaxar sulfate (JAN/USAN) |
D09766 |
CYP3A4, CYP2J2 |
|
|
| Vorasidenib (USAN/INN) |
D11834 |
CYP1A2; CYP2B6, CYP2C8, CYP2C9, CYP2C19, CYP2D6, CYP3A |
|
|
| Vorasidenib citrate (USAN) |
D11835 |
CYP1A2; CYP2B6, CYP2C8, CYP2C9, CYP2C19, CYP2D6, CYP3A |
|
|
| Voriconazole (JP18/USP/INN) |
D00578 |
|
CYP3A |
|
| Vorinostat (JAN/USAN) |
D06320 |
UGT |
|
|
| Vortioxetine (USAN) |
D10184 |
CYP2D6; CYP3A4, CYP3A5, CYP2C19, CYP2C9, CYP2A6, CYP2C8, CYP2B6 |
|
|
| Vortioxetine hemihydrobromide (USAN) |
D12544 |
CYP2D6; CYP3A4, CYP3A5, CYP2C19, CYP2C9, CYP2A6, CYP2C8, CYP2B6 |
|
|
| Vortioxetine hydrobromide (JAN/USAN) |
D10185 |
CYP2D6; CYP3A4, CYP3A5, CYP2C19, CYP2C9, CYP2A6, CYP2C8, CYP2B6 |
|
|
| Voxelotor (USAN) |
D11330 |
CYP3A4; CYP2C19, CYP2B6, CYP2C9 |
|
|
| Warfarin (INN) |
D08682 |
CYP2C9 |
|
|
| Warfarin potassium (JP18) |
D01280 |
CYP2C9 |
|
|
| Warfarin sodium (USP) |
D00564 |
CYP2C9 |
|
|
| Zaleplon (JAN/USP/INN) |
D00530 |
AOX1, CYP3A4 |
|
|
| Zanubrutinib (JAN/USAN/INN) |
D11422 |
CYP3A |
|
|
| Zilucoplan (USAN/INN) |
D12357 |
CYP4F2 |
|
|
| Zilucoplan sodium (JAN) |
D12356 |
CYP4F2 |
|
|
| Zolmitriptan (JAN/USP/INN) |
D00415 |
CYP1A2, MAOA |
|
|
| Zolpidem (INN) |
D08690 |
CYP3A4; CYP2C9, CYP1A2 |
|
|
| Zolpidem tartrate (JP18/USP) |
D00706 |
CYP3A4; CYP2C9, CYP1A2 |
|
|
| Zonisamide (JP18/USP/INN) |
D00538 |
CYP3A |
|
|
| Zopiclone (JP18/INN) |
D01372 |
CYP3A4; CYP2C8 |
|
|
| Zuclopenthixol (INN) |
D03556 |
CYP2D6 |
|
|
| Zuclopenthixol acetate |
D08691 |
CYP2D6 |
|
|
| Zuclopenthixol decanoate |
D08692 |
CYP2D6 |
|
|
| Zuclopenthixol dihydrochloride |
D08693 |
CYP2D6 |
|
|
| Zuranolone (JAN/USAN/INN) |
D11793 |
CYP3A4 |
|
|
| dl-Methylephedrine hydrochloride, dihydrocodeine phosphate, diprophylline, diphenhydramine salicylate, acetaminophen and bromovalerylurea |
D08695 |
UGT2B7, UGT2B4; CYP3A4, CYP2D6 |
|
|
| l-Isoprenaline hydrochloride (JP18) |
D02150 |
COMT |
|
|
Drug Metabolizing Enzymes and Transporters