1. Oxidoreductases

   1.1  Acting on the CH-OH group of donors

     1.1.1  With NAD+ or NADP+ as acceptor

       1.1.1.1  alcohol dehydrogenase

       1.1.1.2  alcohol dehydrogenase (NADP+)

       1.1.1.3  homoserine dehydrogenase

       1.1.1.4  (R,R)-butanediol dehydrogenase

       1.1.1.6  glycerol dehydrogenase

       1.1.1.7  propanediol-phosphate dehydrogenase

       1.1.1.8  glycerol-3-phosphate dehydrogenase (NAD+)

       1.1.1.9  D-xylulose reductase

       1.1.1.10  L-xylulose reductase

       1.1.1.11  D-arabinitol 4-dehydrogenase

       1.1.1.12  L-arabinitol 4-dehydrogenase

       1.1.1.13  L-arabinitol 2-dehydrogenase

       1.1.1.14  L-iditol 2-dehydrogenase

       1.1.1.15  D-iditol 2-dehydrogenase

       1.1.1.16  galactitol 2-dehydrogenase

       1.1.1.17  mannitol-1-phosphate 5-dehydrogenase

       1.1.1.18  inositol 2-dehydrogenase

       1.1.1.19  glucuronate reductase

       1.1.1.20  glucuronolactone reductase

       1.1.1.21  aldose reductase

       1.1.1.22  UDP-glucose 6-dehydrogenase

       1.1.1.23  histidinol dehydrogenase

       1.1.1.24  quinate/shikimate dehydrogenase (NAD+)

       1.1.1.25  shikimate dehydrogenase (NADP+)

       1.1.1.26  glyoxylate reductase

       1.1.1.27  L-lactate dehydrogenase

       1.1.1.28  D-lactate dehydrogenase

       1.1.1.29  glycerate dehydrogenase

       1.1.1.30  3-hydroxybutyrate dehydrogenase

       1.1.1.31  3-hydroxyisobutyrate dehydrogenase

       1.1.1.34  hydroxymethylglutaryl-CoA reductase (NADPH)

       1.1.1.35  3-hydroxyacyl-CoA dehydrogenase

       1.1.1.36  acetoacetyl-CoA reductase

       1.1.1.37  malate dehydrogenase

       1.1.1.38  malate dehydrogenase (oxaloacetate-decarboxylating)

       1.1.1.39  malate dehydrogenase (decarboxylating)

       1.1.1.40  malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+)

       1.1.1.41  isocitrate dehydrogenase (NAD+)

       1.1.1.42  isocitrate dehydrogenase (NADP+)

       1.1.1.43  phosphogluconate 2-dehydrogenase

       1.1.1.44  phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating)

       1.1.1.45  L-gulonate 3-dehydrogenase

       1.1.1.46  L-arabinose 1-dehydrogenase

       1.1.1.47  glucose 1-dehydrogenase [NAD(P)+]

       1.1.1.48  D-galactose 1-dehydrogenase

       1.1.1.49  glucose-6-phosphate dehydrogenase (NADP+)

       1.1.1.50  3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)

       1.1.1.51  3(or 17)beta-hydroxysteroid dehydrogenase

       1.1.1.52  3alpha-hydroxycholanate dehydrogenase (NAD+)

       1.1.1.53  3alpha(or 20beta)-hydroxysteroid dehydrogenase

       1.1.1.54  allyl-alcohol dehydrogenase

       1.1.1.55  lactaldehyde reductase (NADPH)

       1.1.1.56  ribitol 2-dehydrogenase

       1.1.1.57  fructuronate reductase

       1.1.1.58  tagaturonate reductase

       1.1.1.59  3-hydroxypropionate dehydrogenase

       1.1.1.60  2-hydroxy-3-oxopropionate reductase

       1.1.1.61  4-hydroxybutyrate dehydrogenase

       1.1.1.62  17beta-estradiol 17-dehydrogenase

       1.1.1.64  testosterone 17beta-dehydrogenase (NADP+)

       1.1.1.65  pyridoxine 4-dehydrogenase

       1.1.1.66  omega-hydroxydecanoate dehydrogenase

       1.1.1.67  mannitol 2-dehydrogenase

       1.1.1.69  gluconate 5-dehydrogenase

       1.1.1.71  alcohol dehydrogenase [NAD(P)+]

       1.1.1.72  glycerol dehydrogenase (NADP+)

       1.1.1.73  octanol dehydrogenase

       1.1.1.75  (R)-aminopropanol dehydrogenase

       1.1.1.76  (S,S)-butanediol dehydrogenase

       1.1.1.77  lactaldehyde reductase

       1.1.1.78  methylglyoxal reductase (NADH)

       1.1.1.79  glyoxylate reductase (NADP+)

       1.1.1.80  isopropanol dehydrogenase (NADP+)

       1.1.1.81  hydroxypyruvate reductase

       1.1.1.82  malate dehydrogenase (NADP+)

       1.1.1.83  D-malate dehydrogenase (decarboxylating)

       1.1.1.84  dimethylmalate dehydrogenase

       1.1.1.85  3-isopropylmalate dehydrogenase

       1.1.1.86  ketol-acid reductoisomerase (NADP+)

       1.1.1.87  homoisocitrate dehydrogenase

       1.1.1.88  hydroxymethylglutaryl-CoA reductase

       1.1.1.90  aryl-alcohol dehydrogenase

       1.1.1.91  aryl-alcohol dehydrogenase (NADP+)

       1.1.1.92  oxaloglycolate reductase (decarboxylating)

       1.1.1.93  tartrate dehydrogenase

       1.1.1.94  glycerol-3-phosphate dehydrogenase [NAD(P)+]

       1.1.1.95  phosphoglycerate dehydrogenase

       1.1.1.96  diiodophenylpyruvate reductase

       1.1.1.97  3-hydroxybenzyl-alcohol dehydrogenase

       1.1.1.98  (R)-2-hydroxy-fatty-acid dehydrogenase

       1.1.1.99  (S)-2-hydroxy-fatty-acid dehydrogenase

       1.1.1.100  3-oxoacyl-[acyl-carrier-protein] reductase

       1.1.1.101  acylglycerone-phosphate reductase

       1.1.1.102  3-dehydrosphinganine reductase

       1.1.1.103  L-threonine 3-dehydrogenase

       1.1.1.104  4-oxoproline reductase

       1.1.1.105  all-trans-retinol dehydrogenase (NAD+)

       1.1.1.106  pantoate 4-dehydrogenase

       1.1.1.107  pyridoxal 4-dehydrogenase

       1.1.1.108  carnitine 3-dehydrogenase

       1.1.1.110  aromatic 2-oxoacid reductase

       1.1.1.111  3-(imidazol-5-yl)lactate dehydrogenase

       1.1.1.112  indanol dehydrogenase

       1.1.1.113  L-xylose 1-dehydrogenase

       1.1.1.114  apiose 1-reductase

       1.1.1.115  ribose 1-dehydrogenase (NADP+)

       1.1.1.116  D-arabinose 1-dehydrogenase (NAD+)

       1.1.1.117  D-arabinose 1-dehydrogenase [NAD(P)+]

       1.1.1.118  glucose 1-dehydrogenase (NAD+)

       1.1.1.119  glucose 1-dehydrogenase (NADP+)

       1.1.1.120  galactose 1-dehydrogenase (NADP+)

       1.1.1.121  aldose 1-dehydrogenase (NAD+)

       1.1.1.122  D-threo-aldose 1-dehydrogenase

       1.1.1.123  sorbose 5-dehydrogenase (NADP+)

       1.1.1.124  fructose 5-dehydrogenase (NADP+)

       1.1.1.125  2-deoxy-D-gluconate 3-dehydrogenase

       1.1.1.126  2-dehydro-3-deoxy-D-gluconate 6-dehydrogenase

       1.1.1.127  2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase

       1.1.1.129  L-threonate 3-dehydrogenase

       1.1.1.130  3-dehydro-L-gulonate 2-dehydrogenase

       1.1.1.131  mannuronate reductase

       1.1.1.132  GDP-mannose 6-dehydrogenase

       1.1.1.133  dTDP-4-dehydrorhamnose reductase

       1.1.1.134  dTDP-6-deoxy-L-talose 4-dehydrogenase (NADP+)

       1.1.1.135  GDP-6-deoxy-D-talose 4-dehydrogenase

       1.1.1.136  UDP-N-acetylglucosamine 6-dehydrogenase

       1.1.1.137  ribitol-5-phosphate 2-dehydrogenase

       1.1.1.138  mannitol 2-dehydrogenase (NADP+)

       1.1.1.140  sorbitol-6-phosphate 2-dehydrogenase

       1.1.1.141  15-hydroxyprostaglandin dehydrogenase (NAD+)

       1.1.1.142  D-pinitol dehydrogenase

       1.1.1.143  sequoyitol dehydrogenase

       1.1.1.144  perillyl-alcohol dehydrogenase

       1.1.1.145  3beta-hydroxy-Delta5-steroid dehydrogenase

       1.1.1.146  11beta-hydroxysteroid dehydrogenase

       1.1.1.147  16alpha-hydroxysteroid dehydrogenase

       1.1.1.148  estradiol 17alpha-dehydrogenase

       1.1.1.149  20alpha-hydroxysteroid dehydrogenase

       1.1.1.150  21-hydroxysteroid dehydrogenase (NAD+)

       1.1.1.151  21-hydroxysteroid dehydrogenase (NADP+)

       1.1.1.152  3alpha-hydroxy-5beta-androstane-17-one 3alpha-dehydrogenase

       1.1.1.153  sepiapterin reductase (L-erythro-7,8-dihydrobiopterin-forming)

       1.1.1.154  ureidoglycolate dehydrogenase [NAD(P)+]

       1.1.1.156  glycerol 2-dehydrogenase (NADP+)

       1.1.1.157  3-hydroxybutyryl-CoA dehydrogenase

       1.1.1.159  7alpha-hydroxysteroid dehydrogenase

       1.1.1.160  dihydrobunolol dehydrogenase

       1.1.1.162  erythrulose reductase

       1.1.1.163  cyclopentanol dehydrogenase

       1.1.1.164  hexadecanol dehydrogenase

       1.1.1.165  2-alkyn-1-ol dehydrogenase

       1.1.1.166  hydroxycyclohexanecarboxylate dehydrogenase

       1.1.1.167  hydroxymalonate dehydrogenase

       1.1.1.168  2-dehydropantolactone reductase (Re-specific)

       1.1.1.169  2-dehydropantoate 2-reductase

       1.1.1.170  3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating)

       1.1.1.172  2-oxoadipate reductase

       1.1.1.173  L-rhamnose 1-dehydrogenase

       1.1.1.174  cyclohexane-1,2-diol dehydrogenase

       1.1.1.175  D-xylose 1-dehydrogenase

       1.1.1.176  12alpha-hydroxysteroid dehydrogenase

       1.1.1.177  glycerol-3-phosphate 1-dehydrogenase (NADP+)

       1.1.1.178  3-hydroxy-2-methylbutyryl-CoA dehydrogenase

       1.1.1.179  D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming)

       1.1.1.181  cholest-5-ene-3beta,7alpha-diol 3beta-dehydrogenase

       1.1.1.183  geraniol dehydrogenase (NADP+)

       1.1.1.184  carbonyl reductase (NADPH)

       1.1.1.185  L-glycol dehydrogenase

       1.1.1.186  dTDP-galactose 6-dehydrogenase

       1.1.1.187  GDP-4-dehydro-D-rhamnose reductase

       1.1.1.188  prostaglandin-F synthase

       1.1.1.189  prostaglandin-E2 9-reductase

       1.1.1.190  indole-3-acetaldehyde reductase (NADH)

       1.1.1.191  indole-3-acetaldehyde reductase (NADPH)

       1.1.1.192  long-chain-alcohol dehydrogenase

       1.1.1.193  5-amino-6-(5-phosphoribosylamino)uracil reductase

       1.1.1.194  coniferyl-alcohol dehydrogenase

       1.1.1.195  cinnamyl-alcohol dehydrogenase

       1.1.1.196  15-hydroxyprostaglandin-D dehydrogenase (NADP+)

       1.1.1.197  15-hydroxyprostaglandin dehydrogenase (NADP+)

       1.1.1.198  (+)-borneol dehydrogenase

       1.1.1.199  (S)-usnate reductase

       1.1.1.200  aldose-6-phosphate reductase (NADPH)

       1.1.1.201  7beta-hydroxysteroid dehydrogenase (NADP+)

       1.1.1.202  1,3-propanediol dehydrogenase

       1.1.1.203  uronate dehydrogenase

       1.1.1.205  IMP dehydrogenase

       1.1.1.206  tropinone reductase I

       1.1.1.207  (-)-menthol dehydrogenase

       1.1.1.208  (+)-neomenthol dehydrogenase

       1.1.1.209  3(or 17)alpha-hydroxysteroid dehydrogenase

       1.1.1.210  3beta(or 20alpha)-hydroxysteroid dehydrogenase

       1.1.1.211  long-chain-3-hydroxyacyl-CoA dehydrogenase

       1.1.1.212  3-oxoacyl-[acyl-carrier-protein] reductase (NADH)

       1.1.1.213  3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)

       1.1.1.214  2-dehydropantolactone reductase (Si-specific)

       1.1.1.215  gluconate 2-dehydrogenase

       1.1.1.216  farnesol dehydrogenase (NADP+)

       1.1.1.217  benzyl-2-methyl-hydroxybutyrate dehydrogenase

       1.1.1.218  morphine 6-dehydrogenase

       1.1.1.219  dihydroflavonol 4-reductase

       1.1.1.220  6-pyruvoyltetrahydropterin 2'-reductase

       1.1.1.221  vomifoliol dehydrogenase

       1.1.1.223  isopiperitenol dehydrogenase

       1.1.1.224  mannose-6-phosphate 6-reductase

       1.1.1.225  chlordecone reductase

       1.1.1.226  trans-4-hydroxycyclohexanecarboxylate dehydrogenase

       1.1.1.227  (-)-borneol dehydrogenase

       1.1.1.228  (+)-sabinol dehydrogenase

       1.1.1.229  diethyl 2-methyl-3-oxosuccinate reductase

       1.1.1.230  3alpha-hydroxyglycyrrhetinate dehydrogenase

       1.1.1.231  15-hydroxyprostaglandin-I dehydrogenase (NADP+)

       1.1.1.232  15-hydroxyicosatetraenoate dehydrogenase

       1.1.1.233  N-acylmannosamine 1-dehydrogenase

       1.1.1.234  flavanone 4-reductase

       1.1.1.235  8-oxocoformycin reductase

       1.1.1.236  tropinone reductase II

       1.1.1.237  hydroxyphenylpyruvate reductase

       1.1.1.238  12beta-hydroxysteroid dehydrogenase

       1.1.1.239  3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)

       1.1.1.240  N-acetylhexosamine 1-dehydrogenase

       1.1.1.241  6-endo-hydroxycineole dehydrogenase

       1.1.1.243  carveol dehydrogenase

       1.1.1.244  methanol dehydrogenase

       1.1.1.245  cyclohexanol dehydrogenase

       1.1.1.247  codeinone reductase (NADPH)

       1.1.1.248  salutaridine reductase (NADPH)

       1.1.1.250  D-arabinitol 2-dehydrogenase

       1.1.1.251  galactitol-1-phosphate 5-dehydrogenase

       1.1.1.252  tetrahydroxynaphthalene reductase

       1.1.1.254  (S)-carnitine 3-dehydrogenase

       1.1.1.255  mannitol dehydrogenase

       1.1.1.256  fluoren-9-ol dehydrogenase

       1.1.1.257  4-(hydroxymethyl)benzenesulfonate dehydrogenase

       1.1.1.258  6-hydroxyhexanoate dehydrogenase

       1.1.1.259  3-hydroxypimeloyl-CoA dehydrogenase

       1.1.1.260  sulcatone reductase

       1.1.1.261  sn-glycerol-1-phosphate dehydrogenase

       1.1.1.262  4-hydroxythreonine-4-phosphate dehydrogenase

       1.1.1.263  1,5-anhydro-D-fructose reductase

       1.1.1.264  L-idonate 5-dehydrogenase

       1.1.1.265  3-methylbutanal reductase

       1.1.1.266  dTDP-4-dehydro-6-deoxyglucose reductase

       1.1.1.267  1-deoxy-D-xylulose-5-phosphate reductoisomerase

       1.1.1.268  2-(R)-hydroxypropyl-CoM dehydrogenase

       1.1.1.269  2-(S)-hydroxypropyl-CoM dehydrogenase

       1.1.1.270  3beta-hydroxysteroid 3-dehydrogenase

       1.1.1.271  GDP-L-fucose synthase

       1.1.1.272  D-2-hydroxyacid dehydrogenase (NADP+)

       1.1.1.273  vellosimine dehydrogenase

       1.1.1.274  2,5-didehydrogluconate reductase (2-dehydro-D-gluconate-forming)

       1.1.1.275  (+)-trans-carveol dehydrogenase

       1.1.1.276  serine 3-dehydrogenase (NADP+)

       1.1.1.277  3beta-hydroxy-5beta-steroid dehydrogenase

       1.1.1.278  3beta-hydroxy-5alpha-steroid dehydrogenase

       1.1.1.279  (R)-3-hydroxyacid-ester dehydrogenase

       1.1.1.280  (S)-3-hydroxyacid-ester dehydrogenase

       1.1.1.281  GDP-4-dehydro-6-deoxy-D-mannose reductase

       1.1.1.282  quinate/shikimate dehydrogenase [NAD(P)+]

       1.1.1.283  methylglyoxal reductase (NADPH)

       1.1.1.284  S-(hydroxymethyl)glutathione dehydrogenase

       1.1.1.285  3''-deamino-3''-oxonicotianamine reductase

       1.1.1.286  isocitrate---homoisocitrate dehydrogenase

       1.1.1.287  D-arabinitol dehydrogenase (NADP+)

       1.1.1.288  xanthoxin dehydrogenase

       1.1.1.289  sorbose reductase

       1.1.1.290  4-phosphoerythronate dehydrogenase

       1.1.1.291  2-hydroxymethylglutarate dehydrogenase

       1.1.1.292  1,5-anhydro-D-fructose reductase (1,5-anhydro-D-mannitol-forming)

       1.1.1.294  chlorophyll(ide) b reductase

       1.1.1.295  momilactone-A synthase

       1.1.1.296  dihydrocarveol dehydrogenase

       1.1.1.297  limonene-1,2-diol dehydrogenase

       1.1.1.298  3-hydroxypropionate dehydrogenase (NADP+)

       1.1.1.299  malate dehydrogenase [NAD(P)+]

       1.1.1.300  NADP-retinol dehydrogenase

       1.1.1.301  D-arabitol-phosphate dehydrogenase

       1.1.1.302  2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase

       1.1.1.303  diacetyl reductase [(R)-acetoin forming]

       1.1.1.304  diacetyl reductase [(S)-acetoin forming]

       1.1.1.305  UDP-glucuronic acid dehydrogenase (UDP-4-keto-hexauronic acid decarboxylating)

       1.1.1.306  S-(hydroxymethyl)mycothiol dehydrogenase

       1.1.1.307  D-xylose reductase [NAD(P)H]

       1.1.1.308  sulfopropanediol 3-dehydrogenase

       1.1.1.309  phosphonoacetaldehyde reductase (NADH)

       1.1.1.310  (S)-sulfolactate dehydrogenase

       1.1.1.311  (S)-1-phenylethanol dehydrogenase

       1.1.1.312  2-hydroxy-4-carboxymuconate semialdehyde hemiacetal dehydrogenase

       1.1.1.313  sulfoacetaldehyde reductase (NADPH)

       1.1.1.315  11-cis-retinol dehydrogenase

       1.1.1.316  L-galactose 1-dehydrogenase

       1.1.1.317  perakine reductase

       1.1.1.318  eugenol synthase

       1.1.1.319  isoeugenol synthase

       1.1.1.320  benzil reductase [(S)-benzoin forming]

       1.1.1.321  benzil reductase [(R)-benzoin forming]

       1.1.1.322  (-)-endo-fenchol dehydrogenase

       1.1.1.323  (+)-thujan-3-ol dehydrogenase

       1.1.1.324  8-hydroxygeraniol dehydrogenase

       1.1.1.325  sepiapterin reductase (L-threo-7,8-dihydrobiopterin-forming)

       1.1.1.326  zerumbone synthase

       1.1.1.327  5-exo-hydroxycamphor dehydrogenase

       1.1.1.328  nicotine blue oxidoreductase

       1.1.1.329  2-deoxy-scyllo-inosamine dehydrogenase

       1.1.1.330  very-long-chain 3-oxoacyl-CoA reductase

       1.1.1.331  secoisolariciresinol dehydrogenase

       1.1.1.332  chanoclavine-I dehydrogenase

       1.1.1.333  decaprenylphospho-beta-D-erythro-pentofuranosid-2-ulose 2-reductase

       1.1.1.334  methylecgonone reductase

       1.1.1.335  UDP-N-acetyl-2-amino-2-deoxyglucuronate dehydrogenase

       1.1.1.336  UDP-N-acetyl-D-mannosamine dehydrogenase

       1.1.1.337  L-2-hydroxycarboxylate dehydrogenase (NAD+)

       1.1.1.338  (2R)-3-sulfolactate dehydrogenase (NADP+)

       1.1.1.339  dTDP-6-deoxy-L-talose 4-dehydrogenase (NAD+)

       1.1.1.340  1-deoxy-11beta-hydroxypentalenate dehydrogenase

       1.1.1.341  CDP-abequose synthase

       1.1.1.342  CDP-paratose synthase

       1.1.1.343  phosphogluconate dehydrogenase (NAD+-dependent, decarboxylating)

       1.1.1.344  dTDP-6-deoxy-L-talose 4-dehydrogenase [NAD(P)+]

       1.1.1.345  D-2-hydroxyacid dehydrogenase (NAD+)

       1.1.1.346  2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming)

       1.1.1.347  geraniol dehydrogenase (NAD+)

       1.1.1.348  (3R)-2'-hydroxyisoflavanone reductase

       1.1.1.349  norsolorinic acid ketoreductase

       1.1.1.350  ureidoglycolate dehydrogenase (NAD+)

       1.1.1.351  phosphogluconate dehydrogenase [NAD(P)+-dependent, decarboxylating]

       1.1.1.352  5'-hydroxyaverantin dehydrogenase

       1.1.1.353  versiconal hemiacetal acetate reductase

       1.1.1.354  farnesol dehydrogenase (NAD+)

       1.1.1.355  2'-dehydrokanamycin reductase

       1.1.1.356  GDP-L-colitose synthase

       1.1.1.357  3alpha-hydroxysteroid 3-dehydrogenase

       1.1.1.358  2-dehydropantolactone reductase

       1.1.1.359  aldose 1-dehydrogenase [NAD(P)+]

       1.1.1.360  glucose/galactose 1-dehydrogenase

       1.1.1.361  glucose-6-phosphate 3-dehydrogenase

       1.1.1.362  aklaviketone reductase

       1.1.1.363  glucose-6-phosphate dehydrogenase [NAD(P)+]

       1.1.1.364  dTDP-4-dehydro-6-deoxy-alpha-D-gulose 4-ketoreductase

       1.1.1.365  D-galacturonate reductase

       1.1.1.366  L-idonate 5-dehydrogenase (NAD+)

       1.1.1.367  UDP-2-acetamido-2,6-beta-L-arabino-hexul-4-ose reductase

       1.1.1.368  6-hydroxycyclohex-1-ene-1-carbonyl-CoA dehydrogenase

       1.1.1.369  D-chiro-inositol 1-dehydrogenase

       1.1.1.370  scyllo-inositol 2-dehydrogenase (NAD+)

       1.1.1.371  scyllo-inositol 2-dehydrogenase (NADP+)

       1.1.1.372  D/L-glyceraldehyde reductase

       1.1.1.373  sulfolactaldehyde 3-reductase

       1.1.1.374  UDP-N-acetylglucosamine 3-dehydrogenase

       1.1.1.375  L-2-hydroxycarboxylate dehydrogenase [NAD(P)+]

       1.1.1.376  L-arabinose 1-dehydrogenase [NAD(P)+]

       1.1.1.377  L-rhamnose 1-dehydrogenase (NADP+)

       1.1.1.378  L-rhamnose 1-dehydrogenase [NAD(P)+]

       1.1.1.379  (R)-mandelate dehydrogenase

       1.1.1.380  L-gulonate 5-dehydrogenase

       1.1.1.381  3-hydroxy acid dehydrogenase

       1.1.1.382  ketol-acid reductoisomerase (NAD+)

       1.1.1.383  ketol-acid reductoisomerase [NAD(P)+]

       1.1.1.384  dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose 3-reductase

       1.1.1.385  dihydroanticapsin dehydrogenase

       1.1.1.386  ipsdienol dehydrogenase

       1.1.1.387  L-serine 3-dehydrogenase (NAD+)

       1.1.1.388  glucose-6-phosphate dehydrogenase (NAD+)

       1.1.1.389  2-dehydro-3-deoxy-L-galactonate 5-dehydrogenase

       1.1.1.390  sulfoquinovose 1-dehydrogenase

       1.1.1.391  3beta-hydroxycholanate 3-dehydrogenase (NAD+)

       1.1.1.392  3alpha-hydroxycholanate dehydrogenase (NADP+)

       1.1.1.393  3beta-hydroxycholanate 3-dehydrogenase (NADP+)

       1.1.1.394  aurachin B dehydrogenase

       1.1.1.395  3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase

       1.1.1.396  bacteriochlorophyllide a dehydrogenase

       1.1.1.397  beta-methylindole-3-pyruvate reductase

       1.1.1.398  2-glutathionyl-2-methylbut-3-en-1-ol dehydrogenase

       1.1.1.399  2-oxoglutarate reductase

       1.1.1.400  2-methyl-1,2-propanediol dehydrogenase

       1.1.1.401  2-dehydro-3-deoxy-L-rhamnonate dehydrogenase (NAD+)

       1.1.1.402  D-erythritol 1-phosphate dehydrogenase

       1.1.1.403  D-threitol dehydrogenase (NAD+)

       1.1.1.404  tetrachlorobenzoquinone reductase

       1.1.1.405  ribitol-5-phosphate 2-dehydrogenase (NADP+)

       1.1.1.406  galactitol 2-dehydrogenase (L-tagatose-forming)

       1.1.1.407  D-altritol 5-dehydrogenase

       1.1.1.408  4-phospho-D-threonate 3-dehydrogenase

       1.1.1.409  4-phospho-D-erythronate 3-dehydrogenase

       1.1.1.410  D-erythronate 2-dehydrogenase

       1.1.1.411  L-threonate 2-dehydrogenase

       1.1.1.412  2-alkyl-3-oxoalkanoate reductase

       1.1.1.413  A-factor type gamma-butyrolactone 1'-reductase (1S-forming)

       1.1.1.414  L-galactonate 5-dehydrogenase

       1.1.1.415  noscapine synthase

       1.1.1.416  isopyridoxal dehydrogenase (5-pyridoxolactone-forming)

       1.1.1.417  3beta-hydroxysteroid-4beta-carboxylate 3-dehydrogenase (decarboxylating)

       1.1.1.418  plant 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating)

       1.1.1.419  nepetalactol dehydrogenase

       1.1.1.420  D-apiose dehydrogenase

       1.1.1.421  D-apionate oxidoisomerase

       1.1.1.422  pseudoephedrine dehydrogenase

       1.1.1.423  (1R,2S)-ephedrine 1-dehydrogenase

       1.1.1.424  D-xylose 1-dehydrogenase (NADP+, D-xylono-1,4-lactone-forming)

       1.1.1.425  levoglucosan dehydrogenase

       1.1.1.426  UDP-N-acetyl-alpha-D-quinovosamine dehydrogenase

       1.1.1.427  D-arabinose 1-dehydrogenase (NADP+)

       1.1.1.428  4-methylthio 2-oxobutanoate reductase (NADH)

       1.1.1.429  (2S)-[(R)-hydroxy(phenyl)methyl]succinyl-CoA dehydrogenase

       1.1.1.430  D-xylose reductase (NADH)

       1.1.1.431  D-xylose reductase (NADPH)

       1.1.1.432  6-dehydroglucose reductase

       1.1.1.433  sulfoacetaldehyde reductase (NADH)

       1.1.1.434  2-dehydro-3-deoxy-L-fuconate 4-dehydrogenase

       1.1.1.435  L-fucose dehydrogenase

       1.1.1.436  lactate dehydrogenase (NAD+,ferredoxin)

       1.1.1.437  5-dehydrofumagillol 5-reductase

       1.1.1.438  cis-4-hydroxycyclohexanecarboxylate dehydrogenase

       1.1.1.439  17-dehydrostemmadenine reductase

       1.1.1.440  rhazimal reductase

       1.1.1.441  polyprenol dehydrogenase [NAD(P)H]

     1.1.2  With a cytochrome as acceptor

     1.1.3  With oxygen as acceptor

     1.1.5  With a quinone or similar compound as acceptor

     1.1.7  With an iron-sulfur protein as acceptor

     1.1.9  With a copper protein as acceptor

     1.1.98  With other, known, physiological acceptors

       1.1.98.2  glucose-6-phosphate dehydrogenase (coenzyme-F420)

       1.1.98.3  decaprenylphospho-beta-D-ribofuranose 2-dehydrogenase

       1.1.98.4  F420H2:quinone oxidoreductase

       1.1.98.5  secondary-alcohol dehydrogenase (coenzyme-F420)

       1.1.98.6  ribonucleoside-triphosphate reductase (formate)

       1.1.98.7  serine-type anaerobic sulfatase-maturating enzyme

     1.1.99  With unknown physiological acceptors

   1.2  Acting on the aldehyde or oxo group of donors

     1.2.1  With NAD+ or NADP+ as acceptor

       1.2.1.3  aldehyde dehydrogenase (NAD+)

       1.2.1.4  aldehyde dehydrogenase (NADP+)

       1.2.1.5  aldehyde dehydrogenase [NAD(P)+]

       1.2.1.7  benzaldehyde dehydrogenase (NADP+)

       1.2.1.8  betaine-aldehyde dehydrogenase

       1.2.1.9  glyceraldehyde-3-phosphate dehydrogenase (NADP+)

       1.2.1.10  acetaldehyde dehydrogenase (acetylating)

       1.2.1.11  aspartate-semialdehyde dehydrogenase

       1.2.1.12  glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)

       1.2.1.13  glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating)

       1.2.1.15  malonate-semialdehyde dehydrogenase

       1.2.1.16  succinate-semialdehyde dehydrogenase [NAD(P)+]

       1.2.1.17  glyoxylate dehydrogenase (acylating)

       1.2.1.18  malonate-semialdehyde dehydrogenase (acetylating)

       1.2.1.19  aminobutyraldehyde dehydrogenase

       1.2.1.20  glutarate-semialdehyde dehydrogenase

       1.2.1.21  glycolaldehyde dehydrogenase

       1.2.1.22  lactaldehyde dehydrogenase

       1.2.1.23  2-oxoaldehyde dehydrogenase (NAD+)

       1.2.1.24  succinate-semialdehyde dehydrogenase (NAD+)

       1.2.1.25  branched-chain alpha-keto acid dehydrogenase system

       1.2.1.26  2,5-dioxovalerate dehydrogenase

       1.2.1.27  methylmalonate-semialdehyde dehydrogenase (CoA-acylating)

       1.2.1.28  benzaldehyde dehydrogenase (NAD+)

       1.2.1.29  aryl-aldehyde dehydrogenase

       1.2.1.30  carboxylate reductase (NADP+)

       1.2.1.31  L-aminoadipate-semialdehyde dehydrogenase

       1.2.1.32  aminomuconate-semialdehyde dehydrogenase

       1.2.1.33  (R)-dehydropantoate dehydrogenase

       1.2.1.36  retinal dehydrogenase

       1.2.1.38  N-acetyl-gamma-glutamyl-phosphate reductase

       1.2.1.39  phenylacetaldehyde dehydrogenase

       1.2.1.41  glutamate-5-semialdehyde dehydrogenase

       1.2.1.42  hexadecanal dehydrogenase (acylating)

       1.2.1.44  cinnamoyl-CoA reductase

       1.2.1.46  formaldehyde dehydrogenase

       1.2.1.47  4-trimethylammoniobutyraldehyde dehydrogenase

       1.2.1.48  long-chain-aldehyde dehydrogenase

       1.2.1.49  2-oxoaldehyde dehydrogenase (NADP+)

       1.2.1.50  long-chain acyl-protein thioester reductase

       1.2.1.51  pyruvate dehydrogenase (NADP+)

       1.2.1.52  oxoglutarate dehydrogenase (NADP+)

       1.2.1.53  4-hydroxyphenylacetaldehyde dehydrogenase

       1.2.1.54  gamma-guanidinobutyraldehyde dehydrogenase

       1.2.1.57  butanal dehydrogenase

       1.2.1.58  phenylglyoxylate dehydrogenase (acylating)

       1.2.1.59  glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating)

       1.2.1.60  5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase

       1.2.1.61  4-hydroxymuconic-semialdehyde dehydrogenase

       1.2.1.62  4-formylbenzenesulfonate dehydrogenase

       1.2.1.63  6-oxohexanoate dehydrogenase

       1.2.1.64  4-hydroxybenzaldehyde dehydrogenase (NAD+)

       1.2.1.65  salicylaldehyde dehydrogenase

       1.2.1.67  vanillin dehydrogenase

       1.2.1.68  coniferyl-aldehyde dehydrogenase

       1.2.1.69  fluoroacetaldehyde dehydrogenase

       1.2.1.70  glutamyl-tRNA reductase

       1.2.1.71  succinylglutamate-semialdehyde dehydrogenase

       1.2.1.72  erythrose-4-phosphate dehydrogenase

       1.2.1.73  sulfoacetaldehyde dehydrogenase

       1.2.1.74  abieta-7,13-dien-18-al dehydrogenase

       1.2.1.75  malonyl-CoA reductase (malonate semialdehyde-forming)

       1.2.1.76  succinate-semialdehyde dehydrogenase (acylating)

       1.2.1.77  3,4-dehydroadipyl-CoA semialdehyde dehydrogenase (NADP+)

       1.2.1.78  2-formylbenzoate dehydrogenase

       1.2.1.79  succinate-semialdehyde dehydrogenase (NADP+)

       1.2.1.80  long-chain acyl-[acyl-carrier-protein] reductase

       1.2.1.81  sulfoacetaldehyde dehydrogenase (acylating)

       1.2.1.82  beta-apo-4'-carotenal dehydrogenase

       1.2.1.83  3-succinoylsemialdehyde-pyridine dehydrogenase

       1.2.1.84  alcohol-forming fatty acyl-CoA reductase (NADPH)

       1.2.1.85  2-hydroxymuconate-6-semialdehyde dehydrogenase

       1.2.1.86  geranial dehydrogenase

       1.2.1.87  propanal dehydrogenase (CoA-propanoylating)

       1.2.1.88  L-glutamate gamma-semialdehyde dehydrogenase

       1.2.1.89  D-glyceraldehyde dehydrogenase (NADP+)

       1.2.1.90  glyceraldehyde-3-phosphate dehydrogenase [NAD(P)+]

       1.2.1.91  3-oxo-5,6-dehydrosuberyl-CoA semialdehyde dehydrogenase

       1.2.1.92  3,6-anhydro-alpha-L-galactose dehydrogenase

       1.2.1.94  farnesal dehydrogenase

       1.2.1.95  L-2-aminoadipate reductase

       1.2.1.96  4-hydroxybenzaldehyde dehydrogenase (NADP+)

       1.2.1.97  3-sulfolactaldehyde dehydrogenase

       1.2.1.98  2-hydroxy-2-methylpropanal dehydrogenase

       1.2.1.99  4-(gamma-glutamylamino)butanal dehydrogenase

       1.2.1.100  5-formyl-3-hydroxy-2-methylpyridine 4-carboxylic acid 5-dehydrogenase

       1.2.1.101  L-tyrosine reductase

       1.2.1.102  isopyridoxal dehydrogenase (5-pyridoxate-forming)

       1.2.1.103  [amino-group carrier protein]-6-phospho-L-2-aminoadipate reductase

       1.2.1.104  pyruvate dehydrogenase system

       1.2.1.105  2-oxoglutarate dehydrogenase system

       1.2.1.106  [amino-group carrier protein]-5-phospho-L-glutamate reductase

       1.2.1.107  glyceraldehyde-3-phosphate dehydrogenase (arsenate-transferring)

       1.2.1.108  alcohol-forming fatty acyl-CoA reductase (NADH)

     1.2.2  With a cytochrome as acceptor

     1.2.3  With oxygen as acceptor

     1.2.4  With a disulfide as acceptor

     1.2.5  With a quinone or similar compound as acceptor

     1.2.7  With an iron-sulfur protein as acceptor

       1.2.7.1  pyruvate synthase

       1.2.7.3  2-oxoglutarate synthase

       1.2.7.4  anaerobic carbon monoxide dehydrogenase

       1.2.7.5  aldehyde ferredoxin oxidoreductase

       1.2.7.6  glyceraldehyde-3-phosphate dehydrogenase (ferredoxin)

       1.2.7.7  3-methyl-2-oxobutanoate dehydrogenase (ferredoxin)

       1.2.7.8  indolepyruvate ferredoxin oxidoreductase

       1.2.7.10  oxalate oxidoreductase

       1.2.7.11  2-oxoacid oxidoreductase (ferredoxin)

       1.2.7.12  formylmethanofuran dehydrogenase

     1.2.98  With other, known, physiological acceptors

     1.2.99  With unknown physiological acceptors

   1.3  Acting on the CH-CH group of donors

     1.3.1  With NAD+ or NADP+ as acceptor

       1.3.1.1  dihydropyrimidine dehydrogenase (NAD+)

       1.3.1.2  dihydropyrimidine dehydrogenase (NADP+)

       1.3.1.3  Delta4-3-oxosteroid 5beta-reductase

       1.3.1.5  cucurbitacin Delta23-reductase

       1.3.1.6  fumarate reductase (NADH)

       1.3.1.7  meso-tartrate dehydrogenase

       1.3.1.8  acyl-CoA dehydrogenase (NADP+)

       1.3.1.9  enoyl-[acyl-carrier-protein] reductase (NADH)

       1.3.1.10  enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)

       1.3.1.11  2-coumarate reductase

       1.3.1.12  prephenate dehydrogenase

       1.3.1.13  prephenate dehydrogenase (NADP+)

       1.3.1.14  dihydroorotate dehydrogenase (NAD+)

       1.3.1.15  dihydroorotate dehydrogenase (NADP+)

       1.3.1.16  beta-nitroacrylate reductase

       1.3.1.17  3-methyleneoxindole reductase

       1.3.1.18  kynurenate-7,8-dihydrodiol dehydrogenase

       1.3.1.19  cis-1,2-dihydrobenzene-1,2-diol dehydrogenase

       1.3.1.20  trans-1,2-dihydrobenzene-1,2-diol dehydrogenase

       1.3.1.21  7-dehydrocholesterol reductase

       1.3.1.22  3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)

       1.3.1.24  biliverdin reductase

       1.3.1.25  1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase

       1.3.1.27  2-hexadecenal reductase

       1.3.1.28  2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase

       1.3.1.29  cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase

       1.3.1.31  2-enoate reductase

       1.3.1.32  maleylacetate reductase

       1.3.1.33  protochlorophyllide reductase

       1.3.1.34  2,4-dienoyl-CoA reductase [(2E)-enoyl-CoA-producing]

       1.3.1.36  geissoschizine dehydrogenase

       1.3.1.37  cis-2-enoyl-CoA reductase (NADPH)

       1.3.1.38  trans-2-enoyl-CoA reductase (NADPH)

       1.3.1.39  enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific)

       1.3.1.40  2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate reductase

       1.3.1.41  xanthommatin reductase

       1.3.1.42  12-oxophytodienoate reductase

       1.3.1.43  arogenate dehydrogenase

       1.3.1.44  trans-2-enoyl-CoA reductase (NAD+)

       1.3.1.45  2'-hydroxyisoflavone reductase

       1.3.1.46  biochanin-A reductase

       1.3.1.47  alpha-santonin 1,2-reductase

       1.3.1.48  13,14-dehydro-15-oxoprostaglandin 13-reductase

       1.3.1.49  cis-3,4-dihydrophenanthrene-3,4-diol dehydrogenase

       1.3.1.51  2'-hydroxydaidzein reductase

       1.3.1.53  (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate dehydrogenase

       1.3.1.54  precorrin-6A reductase

       1.3.1.56  cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase

       1.3.1.57  phloroglucinol reductase

       1.3.1.58  2,3-dihydroxy-2,3-dihydro-p-cumate dehydrogenase

       1.3.1.60  dibenzothiophene dihydrodiol dehydrogenase

       1.3.1.62  pimeloyl-CoA dehydrogenase

       1.3.1.64  phthalate 4,5-cis-dihydrodiol dehydrogenase

       1.3.1.65  5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline dehydrogenase

       1.3.1.66  cis-dihydroethylcatechol dehydrogenase

       1.3.1.67  cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate dehydrogenase

       1.3.1.68  1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate dehydrogenase

       1.3.1.69  zeatin reductase

       1.3.1.70  Delta14-sterol reductase

       1.3.1.71  Delta24(241)-sterol reductase

       1.3.1.72  Delta24-sterol reductase

       1.3.1.73  1,2-dihydrovomilenine 19,20-reductase

       1.3.1.74  2-alkenal reductase [NAD(P)+]

       1.3.1.75  3,8-divinyl protochlorophyllide a 8-vinyl-reductase (NADPH)

       1.3.1.76  precorrin-2 dehydrogenase

       1.3.1.77  anthocyanidin reductase [(2R,3R)-flavan-3-ol-forming]

       1.3.1.78  arogenate dehydrogenase (NADP+)

       1.3.1.79  arogenate dehydrogenase [NAD(P)+]

       1.3.1.81  (+)-pulegone reductase

       1.3.1.82  (-)-isopiperitenone reductase

       1.3.1.83  geranylgeranyl diphosphate reductase

       1.3.1.84  acrylyl-CoA reductase (NADPH)

       1.3.1.85  crotonyl-CoA carboxylase/reductase

       1.3.1.86  crotonyl-CoA reductase

       1.3.1.87  3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate dehydrogenase

       1.3.1.88  tRNA-dihydrouridine16/17 synthase [NAD(P)+]

       1.3.1.89  tRNA-dihydrouridine47 synthase [NAD(P)+]

       1.3.1.90  tRNA-dihydrouridine20a/20b synthase [NAD(P)+]

       1.3.1.91  tRNA-dihydrouridine20 synthase [NAD(P)+]

       1.3.1.92  artemisinic aldehyde Delta11(13)-reductase

       1.3.1.93  very-long-chain enoyl-CoA reductase

       1.3.1.94  polyprenal reductase

       1.3.1.95  acrylyl-CoA reductase (NADH)

       1.3.1.96  Botryococcus squalene synthase

       1.3.1.97  botryococcene synthase

       1.3.1.98  UDP-N-acetylmuramate dehydrogenase

       1.3.1.100  chanoclavine-I aldehyde reductase

       1.3.1.101  2,3-bis-O-geranylgeranyl-sn-glycerol 1-phosphate reductase [NAD(P)H]

       1.3.1.102  2-alkenal reductase (NADP+)

       1.3.1.103  2-haloacrylate reductase

       1.3.1.104  enoyl-[acyl-carrier-protein] reductase (NADPH)

       1.3.1.105  2-methylene-furan-3-one reductase

       1.3.1.106  cobalt-precorrin-6A reductase

       1.3.1.107  sanguinarine reductase

       1.3.1.108  caffeoyl-CoA reductase

       1.3.1.109  butanoyl-CoA dehydrogenase complex (NAD+, ferredoxin)

       1.3.1.111  geranylgeranyl-bacteriochlorophyllide a reductase

       1.3.1.112  anthocyanidin reductase [(2S)-flavan-3-ol-forming]

       1.3.1.113  (4-alkanoyl-5-oxo-2,5-dihydrofuran-3-yl)methyl phosphate reductase

       1.3.1.114  3-dehydro-bile acid Delta4,6-reductase

       1.3.1.115  3-oxocholoyl-CoA 4-desaturase

       1.3.1.116  7beta-hydroxy-3-oxochol-24-oyl-CoA 4-desaturase

       1.3.1.117  hydroxycinnamoyl-CoA reductase

       1.3.1.118  meromycolic acid enoyl-[acyl-carrier-protein] reductase

       1.3.1.119  chlorobenzene dihydrodiol dehydrogenase

       1.3.1.120  cyclohexane-1-carbonyl-CoA reductase (NADP+)

       1.3.1.121  4-amino-4-deoxyprephenate dehydrogenase

       1.3.1.122  (S)-8-oxocitronellyl enol synthase

       1.3.1.123  8-oxogeranial reductase

       1.3.1.124  2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]

       1.3.1.125  acrylate reductase

       1.3.1.126  2-epi-5-epi-valiolone dehydrogenase

       1.3.1.128  precondylocarpine acetate reductase

     1.3.2  With a cytochrome as acceptor

     1.3.3  With oxygen as acceptor

     1.3.4  With a disulfide as acceptor

       1.3.4.1  fumarate reductase (CoM/CoB)

     1.3.5  With a quinone or related compound as acceptor

     1.3.7  With an iron-sulfur protein as acceptor

     1.3.8  With a flavin as acceptor

       1.3.8.1  short-chain acyl-CoA dehydrogenase

       1.3.8.2  4,4'-diapophytoene desaturase (4,4'-diapolycopene-forming)

       1.3.8.3  (R)-benzylsuccinyl-CoA dehydrogenase

       1.3.8.4  isovaleryl-CoA dehydrogenase

       1.3.8.5  short-chain 2-methylacyl-CoA dehydrogenase

       1.3.8.6  glutaryl-CoA dehydrogenase (ETF)

       1.3.8.7  medium-chain acyl-CoA dehydrogenase

       1.3.8.8  long-chain acyl-CoA dehydrogenase

       1.3.8.9  very-long-chain acyl-CoA dehydrogenase

       1.3.8.10  cyclohex-1-ene-1-carbonyl-CoA dehydrogenase

       1.3.8.11  cyclohexane-1-carbonyl-CoA dehydrogenase (electron-transfer flavoprotein)

       1.3.8.12  (2S)-methylsuccinyl-CoA dehydrogenase

       1.3.8.13  crotonobetainyl-CoA reductase

       1.3.8.14  L-prolyl-[peptidyl-carrier protein] dehydrogenase

       1.3.8.15  3-(aryl)acrylate reductase

       1.3.8.16  2-amino-4-deoxychorismate dehydrogenase

       1.3.8.17  dehydro coenzyme F420 reductase

     1.3.98  With other, known, physiological acceptors

       1.3.98.1  dihydroorotate dehydrogenase (fumarate)

       1.3.98.3  coproporphyrinogen dehydrogenase

       1.3.98.4  5a,11a-dehydrotetracycline reductase

       1.3.98.5  hydrogen peroxide-dependent heme synthase

       1.3.98.6  AdoMet-dependent heme synthase

       1.3.98.7  [mycofactocin precursor peptide]-tyrosine decarboxylase

     1.3.99  With unknown physiological acceptors

       1.3.99.4  3-oxosteroid 1-dehydrogenase

       1.3.99.5  3-oxo-5alpha-steroid 4-dehydrogenase (acceptor)

       1.3.99.6  3-oxo-5beta-steroid 4-dehydrogenase

       1.3.99.8  2-furoyl-CoA dehydrogenase

       1.3.99.14  cyclohexanone dehydrogenase

       1.3.99.16  isoquinoline 1-oxidoreductase

       1.3.99.17  quinoline 2-oxidoreductase

       1.3.99.18  quinaldate 4-oxidoreductase

       1.3.99.19  quinoline-4-carboxylate 2-oxidoreductase

       1.3.99.23  all-trans-retinol 13,14-reductase

       1.3.99.25  carvone reductase

       1.3.99.26  all-trans-zeta-carotene desaturase

       1.3.99.27  1-hydroxycarotenoid 3,4-desaturase

       1.3.99.28  phytoene desaturase (neurosporene-forming)

       1.3.99.29  phytoene desaturase (zeta-carotene-forming)

       1.3.99.30  phytoene desaturase (3,4-didehydrolycopene-forming)

       1.3.99.31  phytoene desaturase (lycopene-forming)

       1.3.99.32  glutaryl-CoA dehydrogenase (acceptor)

       1.3.99.33  urocanate reductase

       1.3.99.36  cypemycin cysteine dehydrogenase (decarboxylating)

       1.3.99.37  1-hydroxy-2-isopentenylcarotenoid 3,4-desaturase

       1.3.99.38  menaquinone-9 beta-reductase

       1.3.99.39  carotenoid phi-ring synthase

       1.3.99.40  carotenoid chi-ring synthase

       1.3.99.41  3-(methylsulfanyl)propanoyl-CoA 2-dehydrogenase

   1.4  Acting on the CH-NH2 group of donors

     1.4.1  With NAD+ or NADP+ as acceptor

       1.4.1.1  alanine dehydrogenase

       1.4.1.2  glutamate dehydrogenase

       1.4.1.3  glutamate dehydrogenase [NAD(P)+]

       1.4.1.4  glutamate dehydrogenase (NADP+)

       1.4.1.5  L-amino-acid dehydrogenase

       1.4.1.7  serine 2-dehydrogenase

       1.4.1.8  valine dehydrogenase (NADP+)

       1.4.1.9  leucine dehydrogenase

       1.4.1.10  glycine dehydrogenase

       1.4.1.11  L-erythro-3,5-diaminohexanoate dehydrogenase

       1.4.1.12  2,4-diaminopentanoate dehydrogenase

       1.4.1.13  glutamate synthase (NADPH)

       1.4.1.14  glutamate synthase (NADH)

       1.4.1.15  lysine dehydrogenase

       1.4.1.16  diaminopimelate dehydrogenase

       1.4.1.17  N-methylalanine dehydrogenase

       1.4.1.18  lysine 6-dehydrogenase

       1.4.1.19  tryptophan dehydrogenase

       1.4.1.20  phenylalanine dehydrogenase

       1.4.1.21  aspartate dehydrogenase

       1.4.1.23  valine dehydrogenase (NAD+)

       1.4.1.24  3-dehydroquinate synthase II

       1.4.1.25  L-arginine dehydrogenase

       1.4.1.26  2,4-diaminopentanoate dehydrogenase (NAD+)

       1.4.1.27  glycine cleavage system

       1.4.1.28  secondary-alkyl amine dehydrogenase [NAD(P)+]

     1.4.2  With a cytochrome as acceptor

     1.4.3  With oxygen as acceptor

     1.4.4  With a disulfide as acceptor

     1.4.5  With a quinone or other compound as acceptor

     1.4.7  With an iron-sulfur protein as acceptor

     1.4.9  With a copper protein as acceptor

     1.4.99  With unknown physiological acceptors

   1.5  Acting on the CH-NH group of donors

     1.5.1  With NAD+ or NADP+ as acceptor

       1.5.1.1  1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase [NAD(P)H]

       1.5.1.2  pyrroline-5-carboxylate reductase

       1.5.1.3  dihydrofolate reductase

       1.5.1.5  methylenetetrahydrofolate dehydrogenase (NADP+)

       1.5.1.6  formyltetrahydrofolate dehydrogenase

       1.5.1.7  saccharopine dehydrogenase (NAD+, L-lysine-forming)

       1.5.1.8  saccharopine dehydrogenase (NADP+, L-lysine-forming)

       1.5.1.9  saccharopine dehydrogenase (NAD+, L-glutamate-forming)

       1.5.1.10  saccharopine dehydrogenase (NADP+, L-glutamate-forming)

       1.5.1.11  D-octopine dehydrogenase

       1.5.1.15  methylenetetrahydrofolate dehydrogenase (NAD+)

       1.5.1.16  D-lysopine dehydrogenase

       1.5.1.17  alanopine dehydrogenase

       1.5.1.18  ephedrine dehydrogenase

       1.5.1.19  D-nopaline dehydrogenase

       1.5.1.20  methylenetetrahydrofolate reductase [NAD(P)H]

       1.5.1.21  1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase (NADPH)

       1.5.1.22  strombine dehydrogenase

       1.5.1.23  tauropine dehydrogenase

       1.5.1.24  N5-(carboxyethyl)ornithine synthase

       1.5.1.25  thiomorpholine-carboxylate dehydrogenase

       1.5.1.26  beta-alanopine dehydrogenase

       1.5.1.27  1,2-dehydroreticulinium reductase (NADPH)

       1.5.1.28  opine dehydrogenase

       1.5.1.30  flavin reductase (NADPH)

       1.5.1.31  berberine reductase

       1.5.1.32  vomilenine reductase

       1.5.1.33  pteridine reductase

       1.5.1.34  6,7-dihydropteridine reductase

       1.5.1.36  flavin reductase (NADH)

       1.5.1.37  FAD reductase (NADH)

       1.5.1.38  FMN reductase (NADPH)

       1.5.1.39  FMN reductase [NAD(P)H]

       1.5.1.40  8-hydroxy-5-deazaflavin:NADPH oxidoreductase

       1.5.1.41  riboflavin reductase [NAD(P)H]

       1.5.1.42  FMN reductase (NADH)

       1.5.1.43  carboxynorspermidine synthase

       1.5.1.44  festuclavine dehydrogenase

       1.5.1.45  FAD reductase [NAD(P)H]

       1.5.1.46  agroclavine dehydrogenase

       1.5.1.47  dihydromethanopterin reductase [NAD(P)+]

       1.5.1.48  2-methyl-1-pyrroline reductase

       1.5.1.49  1-pyrroline-2-carboxylate reductase [NAD(P)H]

       1.5.1.50  dihydromonapterin reductase

       1.5.1.51  N-[(2S)-2-amino-2-carboxyethyl]-L-glutamate dehydrogenase

       1.5.1.52  staphylopine dehydrogenase

       1.5.1.53  methylenetetrahydrofolate reductase (NADPH)

       1.5.1.54  methylenetetrahydrofolate reductase (NADH)

       1.5.1.55  carboxyaminopropylagmatine dehydrogenase

       1.5.1.56  3,17-didehydrostemmadenine reductase

       1.5.1.57  18-hydroxynorfluorocurarine reductase

     1.5.3  With oxygen as acceptor

     1.5.4  With a disulfide as acceptor

     1.5.5  With a quinone or similar compound as acceptor

     1.5.7  With an iron-sulfur protein as acceptor

     1.5.8  With a flavin or flavoprotein as acceptor

     1.5.98  With other, known, physiological acceptors

     1.5.99  With unknown physiological acceptors

   1.6  Acting on NADH or NADPH

     1.6.1  With NAD+ or NADP+ as acceptor

     1.6.2  With a heme protein as acceptor

     1.6.3  With oxygen as acceptor

     1.6.5  With a quinone or similar compound as acceptor

       1.6.5.2  NAD(P)H dehydrogenase (quinone)

       1.6.5.4  monodehydroascorbate reductase (NADH)

       1.6.5.5  NADPH:quinone reductase

       1.6.5.6  p-benzoquinone reductase (NADPH)

       1.6.5.7  2-hydroxy-1,4-benzoquinone reductase

       1.6.5.9  NADH:quinone reductase (non-electrogenic)

       1.6.5.10  NADPH dehydrogenase (quinone)

       1.6.5.12  demethylphylloquinone reductase

     1.6.99  With unknown physiological acceptors

   1.7  Acting on other nitrogenous compounds as donors

     1.7.1  With NAD+ or NADP+ as acceptor

       1.7.1.1  nitrate reductase (NADH)

       1.7.1.2  nitrate reductase [NAD(P)H]

       1.7.1.3  nitrate reductase (NADPH)

       1.7.1.4  nitrite reductase [NAD(P)H]

       1.7.1.5  hyponitrite reductase

       1.7.1.6  azobenzene reductase

       1.7.1.7  GMP reductase

       1.7.1.9  nitroquinoline-N-oxide reductase

       1.7.1.10  hydroxylamine reductase (NADH)

       1.7.1.11  4-(dimethylamino)phenylazoxybenzene reductase

       1.7.1.12  N-hydroxy-2-acetamidofluorene reductase

       1.7.1.13  preQ1 synthase

       1.7.1.14  nitric oxide reductase [NAD(P)+, nitrous oxide-forming]

       1.7.1.15  nitrite reductase (NADH)

       1.7.1.16  nitrobenzene nitroreductase

       1.7.1.17  FMN-dependent NADH-azoreductase

     1.7.2  With a cytochrome as acceptor

       1.7.2.1  nitrite reductase (NO-forming)

       1.7.2.2  nitrite reductase (cytochrome; ammonia-forming)

       1.7.2.3  trimethylamine-N-oxide reductase

       1.7.2.4  nitrous-oxide reductase

       1.7.2.5  nitric oxide reductase (cytochrome c)

       1.7.2.6  hydroxylamine dehydrogenase

       1.7.2.7  hydrazine synthase

       1.7.2.8  hydrazine dehydrogenase

       1.7.2.9  hydroxylamine oxidase

     1.7.3  With oxygen as acceptor

     1.7.5  With a quinone or similar compound as acceptor

     1.7.6  With a nitrogenous group as acceptor

     1.7.7  With an iron-sulfur protein as acceptor

     1.7.99  With unknown physiological acceptors

       1.7.99.1  hydroxylamine reductase

   1.8  Acting on a sulfur group of donors

     1.8.1  With NAD+ or NADP+ as acceptor

       1.8.1.2  assimilatory sulfite reductase (NADPH)

       1.8.1.4  dihydrolipoyl dehydrogenase

       1.8.1.5  2-oxopropyl-CoM reductase (carboxylating)

       1.8.1.6  cystine reductase

       1.8.1.7  glutathione-disulfide reductase

       1.8.1.8  protein-disulfide reductase

       1.8.1.9  thioredoxin-disulfide reductase (NADPH)

       1.8.1.10  CoA-glutathione reductase

       1.8.1.11  asparagusate reductase

       1.8.1.12  trypanothione-disulfide reductase

       1.8.1.13  bis-gamma-glutamylcystine reductase

       1.8.1.14  CoA-disulfide reductase

       1.8.1.15  mycothione reductase

       1.8.1.16  glutathione amide reductase

       1.8.1.17  dimethylsulfone reductase

       1.8.1.18  NAD(P)H sulfur oxidoreductase (CoA-dependent)

       1.8.1.19  sulfide dehydrogenase

       1.8.1.20  4,4'-dithiodibutanoate disulfide reductase

       1.8.1.21  dissimilatory dimethyldisulfide reductase

       1.8.1.22  dissimilatory sulfite reductase system

     1.8.2  With a cytochrome as acceptor

     1.8.3  With oxygen as acceptor

     1.8.4  With a disulfide as acceptor

       1.8.4.1  glutathione---homocystine transhydrogenase

       1.8.4.2  protein-disulfide reductase (glutathione)

       1.8.4.3  glutathione---CoA-glutathione transhydrogenase

       1.8.4.4  glutathione---cystine transhydrogenase

       1.8.4.7  enzyme-thiol transhydrogenase (glutathione-disulfide)

       1.8.4.8  phosphoadenylyl-sulfate reductase (thioredoxin)

       1.8.4.9  adenylyl-sulfate reductase (glutathione)

       1.8.4.10  adenylyl-sulfate reductase (thioredoxin)

       1.8.4.11  peptide-methionine (S)-S-oxide reductase

       1.8.4.12  peptide-methionine (R)-S-oxide reductase

       1.8.4.13  L-methionine (S)-S-oxide reductase

       1.8.4.14  L-methionine (R)-S-oxide reductase

       1.8.4.15  protein dithiol oxidoreductase (disulfide-forming)

       1.8.4.16  thioredoxin:protein disulfide reductase

       1.8.4.17  sulfur-oxidizing heterodisulfide reductase-like enzyme system (type I)

     1.8.5  With a quinone or similar compound as acceptor

       1.8.5.1  glutathione dehydrogenase (ascorbate)

       1.8.5.2  thiosulfate dehydrogenase (quinone)

       1.8.5.3  respiratory dimethylsulfoxide reductase

       1.8.5.4  bacterial sulfide:quinone reductase

       1.8.5.5  thiosulfate reductase (quinone)

       1.8.5.6  sulfite dehydrogenase (quinone)

       1.8.5.7  glutathionyl-hydroquinone reductase

       1.8.5.8  eukaryotic sulfide quinone oxidoreductase

       1.8.5.9  protein dithiol:quinone oxidoreductase DsbB

       1.8.5.10  [DsrC]-trisulfide reductase

     1.8.7  With an iron-sulfur protein as acceptor

     1.8.98  With other, known, physiological acceptors

     1.8.99  With unknown physiological acceptors

   1.9  Acting on a heme group of donors

     1.9.6  With a nitrogenous group as acceptor

       1.9.6.1  nitrate reductase (cytochrome)

   1.10  Acting on diphenols and related substances as donors

     1.10.1  With NAD+ or NADP+ as acceptor

     1.10.3  With oxygen as acceptor

     1.10.5  With a quinone or related compound as acceptor

   1.11  Acting on a peroxide as acceptor

     1.11.1  Peroxidases

       1.11.1.1  NADH peroxidase

       1.11.1.2  NADPH peroxidase

       1.11.1.3  fatty-acid peroxidase

       1.11.1.5  cytochrome-c peroxidase

       1.11.1.6  catalase

       1.11.1.7  peroxidase

       1.11.1.8  iodide peroxidase

       1.11.1.9  glutathione peroxidase

       1.11.1.10  chloride peroxidase

       1.11.1.11  L-ascorbate peroxidase

       1.11.1.12  phospholipid-hydroperoxide glutathione peroxidase

       1.11.1.13  manganese peroxidase

       1.11.1.14  lignin peroxidase

       1.11.1.16  versatile peroxidase

       1.11.1.17  glutathione amide-dependent peroxidase

       1.11.1.18  bromide peroxidase

       1.11.1.19  dye decolorizing peroxidase

       1.11.1.20  prostamide/prostaglandin F2alpha synthase

       1.11.1.21  catalase-peroxidase

       1.11.1.22  hydroperoxy fatty acid reductase

       1.11.1.23  (S)-2-hydroxypropylphosphonic acid epoxidase

       1.11.1.24  thioredoxin-dependent peroxiredoxin

       1.11.1.25  glutaredoxin-dependent peroxiredoxin

       1.11.1.26  NADH-dependent peroxiredoxin

       1.11.1.27  glutathione-dependent peroxiredoxin

       1.11.1.28  lipoyl-dependent peroxiredoxin

       1.11.1.29  mycoredoxin-dependent peroxiredoxin

     1.11.2  Peroxygenases

   1.12  Acting on hydrogen as donor

     1.12.1  With NAD+ or NADP+ as acceptor

     1.12.2  With a cytochrome as acceptor

       1.12.2.1  cytochrome-c3 hydrogenase

     1.12.5  With a quinone or similar compound as acceptor

     1.12.7  With an iron-sulfur protein as acceptor

     1.12.98  With other, known, physiological acceptors

     1.12.99  With unknown physiological acceptors

       1.12.99.6  hydrogenase (acceptor)

   1.13  Acting on single donors with incorporation of molecular oxygen (oxygenases)

     1.13.11  With incorporation of two atoms of oxygen

       1.13.11.1  catechol 1,2-dioxygenase

       1.13.11.2  catechol 2,3-dioxygenase

       1.13.11.3  protocatechuate 3,4-dioxygenase

       1.13.11.4  gentisate 1,2-dioxygenase

       1.13.11.5  homogentisate 1,2-dioxygenase

       1.13.11.6  3-hydroxyanthranilate 3,4-dioxygenase

       1.13.11.8  protocatechuate 4,5-dioxygenase

       1.13.11.9  2,5-dihydroxypyridine 5,6-dioxygenase

       1.13.11.10  7,8-dihydroxykynurenate 8,8a-dioxygenase

       1.13.11.11  tryptophan 2,3-dioxygenase

       1.13.11.12  linoleate 13S-lipoxygenase

       1.13.11.14  2,3-dihydroxybenzoate 3,4-dioxygenase

       1.13.11.15  3,4-dihydroxyphenylacetate 2,3-dioxygenase

       1.13.11.16  3-carboxyethylcatechol 2,3-dioxygenase

       1.13.11.17  indole 2,3-dioxygenase

       1.13.11.18  persulfide dioxygenase

       1.13.11.19  cysteamine dioxygenase

       1.13.11.20  cysteine dioxygenase

       1.13.11.22  caffeate 3,4-dioxygenase

       1.13.11.23  2,3-dihydroxyindole 2,3-dioxygenase

       1.13.11.24  quercetin 2,3-dioxygenase

       1.13.11.25  3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione 4,5-dioxygenase

       1.13.11.26  peptide-tryptophan 2,3-dioxygenase

       1.13.11.27  4-hydroxyphenylpyruvate dioxygenase

       1.13.11.28  2,3-dihydroxybenzoate 2,3-dioxygenase

       1.13.11.29  stizolobate synthase

       1.13.11.30  stizolobinate synthase

       1.13.11.31  arachidonate 12-lipoxygenase

       1.13.11.33  arachidonate 15-lipoxygenase

       1.13.11.34  arachidonate 5-lipoxygenase

       1.13.11.35  pyrogallol 1,2-oxygenase

       1.13.11.36  chloridazon-catechol dioxygenase

       1.13.11.37  hydroxyquinol 1,2-dioxygenase

       1.13.11.38  1-hydroxy-2-naphthoate 1,2-dioxygenase

       1.13.11.39  biphenyl-2,3-diol 1,2-dioxygenase

       1.13.11.40  arachidonate 8-lipoxygenase

       1.13.11.41  2,4'-dihydroxyacetophenone dioxygenase

       1.13.11.43  lignostilbene alphabeta-dioxygenase

       1.13.11.45  linoleate 11-lipoxygenase

       1.13.11.46  4-hydroxymandelate synthase

       1.13.11.47  3-hydroxy-4-oxoquinoline 2,4-dioxygenase

       1.13.11.48  3-hydroxy-2-methylquinolin-4-one 2,4-dioxygenase

       1.13.11.49  chlorite O2-lyase

       1.13.11.50  acetylacetone-cleaving enzyme

       1.13.11.51  9-cis-epoxycarotenoid dioxygenase

       1.13.11.52  indoleamine 2,3-dioxygenase

       1.13.11.53  acireductone dioxygenase (Ni2+-requiring)

       1.13.11.54  acireductone dioxygenase [iron(II)-requiring]

       1.13.11.55  sulfur oxygenase/reductase

       1.13.11.56  1,2-dihydroxynaphthalene dioxygenase

       1.13.11.57  gallate dioxygenase

       1.13.11.58  linoleate 9S-lipoxygenase

       1.13.11.59  torulene dioxygenase

       1.13.11.60  linoleate 8R-lipoxygenase

       1.13.11.61  linolenate 9R-lipoxygenase

       1.13.11.62  linoleate 10R-lipoxygenase

       1.13.11.63  beta-carotene 15,15'-dioxygenase

       1.13.11.64  5-nitrosalicylate dioxygenase

       1.13.11.65  carotenoid isomerooxygenase

       1.13.11.66  hydroquinone 1,2-dioxygenase

       1.13.11.67  8'-apo-beta-carotenoid 14',13'-cleaving dioxygenase

       1.13.11.68  9-cis-beta-carotene 9',10'-cleaving dioxygenase

       1.13.11.69  carlactone synthase

       1.13.11.70  all-trans-10'-apo-beta-carotenal 13,14-cleaving dioxygenase

       1.13.11.71  carotenoid-9',10'-cleaving dioxygenase

       1.13.11.72  2-hydroxyethylphosphonate dioxygenase

       1.13.11.73  methylphosphonate synthase

       1.13.11.74  2-aminophenol 1,6-dioxygenase

       1.13.11.75  all-trans-8'-apo-beta-carotenal 15,15'-oxygenase

       1.13.11.76  2-amino-5-chlorophenol 1,6-dioxygenase

       1.13.11.77  oleate 10S-lipoxygenase

       1.13.11.78  2-amino-1-hydroxyethylphosphonate dioxygenase (glycine-forming)

       1.13.11.79  aerobic 5,6-dimethylbenzimidazole synthase

       1.13.11.80  (3,5-dihydroxyphenyl)acetyl-CoA 1,2-dioxygenase

       1.13.11.81  7,8-dihydroneopterin oxygenase

       1.13.11.82  8'-apo-carotenoid 13,14-cleaving dioxygenase

       1.13.11.83  4-hydroxy-3-prenylphenylpyruvate oxygenase

       1.13.11.84  crocetin dialdehyde synthase

       1.13.11.85  exo-cleaving rubber dioxygenase

       1.13.11.86  5-aminosalicylate 1,2-dioxygenase

       1.13.11.87  endo-cleaving rubber dioxygenase

       1.13.11.88  isoeugenol monooxygenase

       1.13.11.89  (hydroxymethyl)phosphonate dioxygenase

       1.13.11.90  [1-hydroxy-2-(trimethylamino)ethyl]phosphonate dioxygenase (glycine-betaine-forming)

       1.13.11.91  3-mercaptopropionate dioxygenase

       1.13.11.92  fatty acid alpha-dioxygenase

       1.13.11.93  2-oxoadipate dioxygenase/decarboxylase

       1.13.11.94  4-vinylguaiacol dioxygenase

       1.13.11.95  2-oxoethane-1-sulfonamide synthase

     1.13.12  With incorporation of one atom of oxygen (internal monooxygenases or internal mixed-function oxidases)

     1.13.99  Miscellaneous

   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen

     1.14.11  With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor

     1.14.12  With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor

     1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor

     1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor